MCID: SPR066
MIFTS: 28

Superficial Siderosis malady

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Superficial Siderosis

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Sources:
51Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Superficial Siderosis:

Name: Superficial Siderosis 51

Characteristics:

Orphanet epidemiological data:

51
superficial siderosis:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Orphanet51 247245
ICD10 via Orphanet28 I69.0

Summaries for Superficial Siderosis

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Wikipedia:68 Superficial hemosiderosis of the central nervous system is a disease of the brain resulting from chronic... more...

MalaCards based summary: Superficial Siderosis is related to superficial siderosis of the central nervous system and prostatitis. An important gene associated with Superficial Siderosis is FTH1 (Ferritin, Heavy Polypeptide 1), and among its related pathways are Insulin receptor recycling and Mineral absorption. Affiliated tissues include brain, breast and prostate, and related mouse phenotype liver/biliary system.

Related Diseases for Superficial Siderosis

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Graphical network of the top 20 diseases related to Superficial Siderosis:



Diseases related to superficial siderosis

Symptoms for Superficial Siderosis

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Drugs & Therapeutics for Superficial Siderosis

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Drugs for Superficial Siderosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IronapprovedPhase 410217439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Dexiron
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
Ed-In-Sol
 
Eisen
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feraheme
Feronate
Ferretts
Ferrlecit
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Infufer
Iron
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Venofer
Vitedyn-Slo
Yieronia
fer
ferrous ascorbate
ferrous fumarate
ferrous gluconate
ferrous glycine sulfate
ferrous iron
ferrous succinate
ferrous sulfate
hierro
2
DeferiproneapprovedPhase 45330652-11-02972
Synonyms:
1,2-Dimethyl-3-hydroxypyrid-4-one
3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
APO-066
CP-20
DN-180-01-AF
Deferipron
 
Deferiprona
Deferiproni
Deferipronum
Deferypron
Dimethylhydroxypyridone
Défériprone
Ferriprox
PL-1
3Iron Chelating AgentsPhase 4178
4Chelating AgentsPhase 4667

Interventional clinical trials:

idNameStatusNCT IDPhase
1Observational Study of Deferiprone (Ferriprox®) in the Treatment of Superficial SiderosisActive, not recruitingNCT01284127Phase 4
2Superficial Siderosis in Patients With Suspected Cerebral Amyloid AngiopathyRecruitingNCT01856699
3Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial HemosiderosisNot yet recruitingNCT02664571

Search NIH Clinical Center for Superficial Siderosis

Genetic Tests for Superficial Siderosis

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Anatomical Context for Superficial Siderosis

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MalaCards organs/tissues related to Superficial Siderosis:

33
Brain, Breast, Prostate, Lung, Bone, Kidney, Testes

Animal Models for Superficial Siderosis or affiliated genes

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MGI Mouse Phenotypes related to Superficial Siderosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.1FTH1, HMOX1

Publications for Superficial Siderosis

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Articles related to Superficial Siderosis:

(show top 50)    (show all 255)
idTitleAuthorsYear
1
Genetically Dissecting Cortical Neurons Involved in Epilepsy in Angelman Syndrome. (27054611)
2016
2
Association between the CTLA-4, CD226, FAS polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis. (25645050)
2015
3
Interstitial pulmonary amyloidosis with WaldenstrAPm's macroglobulinemia. (25748748)
2015
4
Factor Xa dimerization competes with prothrombinase complex formation on platelet-like membrane surfaces. (25572019)
2015
5
Case Report: Glioblastoma Multiforme Complicating Familial Cavernous Malformations. (23942770)
2013
6
High expression of survivin is prognostic of shorter survival but not predictive of adjuvant gemcitabine benefit in patients with resected pancreatic adenocarcinoma. (23124118)
2013
7
Breast sparganosis. (24165318)
2013
8
Tympanoplasty with intact canal wall mastoidectomy for cholesteatoma: Long-term hearing outcomes. (23686395)
2013
9
Prevention of hypoglycemia-induced neuronal death by minocycline. (22998689)
2012
10
P2Y6 receptor signaling pathway mediates inflammatory responses induced by monosodium urate crystals. (22102722)
2012
11
Transient global amnesia as a revealing sign of giant transtentorial meningioma: case report and review of the literature. (21629022)
2011
12
Frontotemporal dementia phenotype associated with MAPT gene duplication. (20634582)
2010
13
Autoantibodies against aquaporin-4 in patients with neuropsychiatric systemic lupus erythematosus and primary SjAPgren's syndrome. (20131265)
2010
14
N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway. (20693288)
2010
15
On the role of FOX transcription factors in adipocyte differentiation and insulin-stimulated glucose uptake. (19244248)
2009
16
While dysferlin and myoferlin are coexpressed in the human placenta, only dysferlin expression is responsive to trophoblast fusion in model systems. (19228595)
2009
17
Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis. (19891773)
2009
18
Absence of angiogenic genes modification in Italian ALS patients. (17113198)
2008
19
Milk composition studies in transgenic goats expressing recombinant human butyrylcholinesterase in the mammary gland. (18483775)
2008
20
Frequency of the IVS4+66A-G polymorphism in the alpha-synuclein gene in patients with Parkinson's disease in north-western Mexico]. (17199224)
2007
21
Vitamin D receptor gene polymorphisms and sputum conversion time in pulmonary tuberculosis patients. (17449323)
2007
22
Cordyceps sinensis mycelium extract induces human premyelocytic leukemia cell apoptosis through mitochondrion pathway. (17202585)
2007
23
Modified Echocardiographic views for concordant atrio-ventricular connection with discordant ventriculo-arterial connection or double outlet right ventricle and sub-pulmonary ventricular septal defect. (22368672)
2007
24
Deubiquitinating enzyme CYLD negatively regulates the ubiquitin- dependent kinase Tak1 and prevents abnormal T cell responses. (17548520)
2007
25
HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney. (16024913)
2005
26
Primary ciliary dyskinesia: clinical presentation, diagnosis and genetics. (16203616)
2005
27
Protein folding by the effects of macromolecular crowding. (14691228)
2004
28
Should renal vein catheterization for selective renin determination be performed in patients with suspected renovascular hypertension?]. (15515466)
2004
29
Impact of IL-1 genotype and smoking status on the prognosis of osseointegrated implants. (15248873)
2004
30
mu-1,2-Peroxobridged di-iron(III) dimer formation in human H-chain ferritin. (11988076)
2002
31
Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normal neonate. (11902741)
2002
32
Nutrient regulation of gene expression by the sterol regulatory element binding proteins: increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivo. (10841543)
2000
33
Role of platelet-activating factor in alveolar septal injury associated with experimentally induced pneumonic pasteurellosis in calves. (10714514)
2000
34
Intracranial hemorrhages in Alagille syndrome. (10802514)
2000
35
Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis. (10380879)
1999
36
Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans. (10469592)
1999
37
Interleukin-1 (IL-1), IL-1 receptor, IL-1 receptor antagonist (IL-1ra)]. (10635966)
1999
38
Adipose tissue metabolism in the postprandial period: microdialysis and arteriovenous techniques compared. (9575826)
1998
39
Investigation into the contractile response of melatonin in the guinea-pig isolated proximal colon: the role of 5-HT4 and melatonin receptors. (9283717)
1997
40
Development of human cytochrome P450-expressing cell lines: application in mutagenicity testing of ochratoxin A. (8542584)
1996
41
Differential alcohol dehydrogenase and malate dehydrogenase isozyme expression in long-term callus tissue cultures of Cereus peruvianus (Cactaceae). (8825939)
1995
42
Test of growth hormone secretion in adults: poor reproducibility of the insulin tolerance test. (7581946)
1995
43
Exploring the mammalian neuromuscular system by analysis of mutations: spinal muscular atrophy and myotonia. (8008830)
1994
44
A case with delayed sleep phase syndrome showing a significant seasonal variation in sleep-wake cycle. (1753481)
1991
45
A scanning electron microscopic study of dentin dysplasia type II in primary dentition. (6589579)
1984
46
Transformation of Fanconi's anemia to acute nonlymphocytic leukemia associated with emergence of monosomy 7. (6733270)
1984
47
Cerebellar capillary hemangioblastoma: its histogenesis studied by organ culture and electron microscopy. (163132)
1975
48
Long-term follow-up study of periarteritis nodosa. (4157287)
1967
49
SOME CLINICAL AND PSYCHOPATHOLOGICAL ASPECTS OF BESTIALITY. (14206452)
1964
50

Variations for Superficial Siderosis

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Expression for genes affiliated with Superficial Siderosis

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Search GEO for disease gene expression data for Superficial Siderosis.

Pathways for genes affiliated with Superficial Siderosis

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GO Terms for genes affiliated with Superficial Siderosis

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Biological processes related to Superficial Siderosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cellular iron ion homeostasisGO:00068799.4FTH1, HMOX1
2transmembrane transportGO:00550859.1FTH1, HMOX1

Sources for Superficial Siderosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet