MCID: SPP008
MIFTS: 40

Suppurative Otitis Media malady

Ear diseases category

Summaries for Suppurative Otitis Media

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A otitis media which involves inflammation of the middle ear with infected effusion containing pus.

MalaCards: Suppurative Otitis Media, also known as suppurative and unspecified otitis media, is related to otitis media and cholesteatoma. An important gene associated with Suppurative Otitis Media is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1). The compounds gabexate mesilate and tirofiban have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and testes.

Aliases & Classifications for Suppurative Otitis Media

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

suppurative otitis media 8 10 60
suppurative and unspecified otitis media 8
suppurative otitis media &/or left 8
otitis media with effusion - purulent 8
right &/or purulent otitis media 8
unspecified suppurative otitis media 8
purulent otitis media nos 8
infection - suppurative 60
suppurative otitis med. 8
purulent otitis media 8


External Ids:

Disease Ontology8 DOID:11506
MeSH34 D010035
ICD9CM27 382, 382.4
ICD1025 H66

Related Diseases for Suppurative Otitis Media

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Suppurative Otitis Media:



Diseases related to suppurative otitis media

Clinical Features for Suppurative Otitis Media

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Drugs & Therapeutics for Suppurative Otitis Media

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Suppurative Otitis Media

Drug clinical trials:

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Search NIH Clinical Center for Suppurative Otitis Media

Search CenterWatch for Suppurative Otitis Media

Genetic Tests for Suppurative Otitis Media

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Anatomical Context for Suppurative Otitis Media

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32MalaCards
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MalaCards organs/tissues related to Suppurative Otitis Media:

32
Bone, Brain, Testes, Temporal lobe

Animal Models for Suppurative Otitis Media or affiliated genes

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Publications for Suppurative Otitis Media

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Sources:
50PubMed
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Articles related to Suppurative Otitis Media:

(show top 50)    (show all 488)
idTitleAuthorsYear
1
Impact of swimming on chronic suppurative otitis media in Aboriginal children: a randomised controlled trial. (23829265)
2013
2
Chronic suppurative otitis media and its association with socio-econonic factors among rural primary school children of bangladesh. (23450091)
2012
3
Prevalence and associated socio-demographic factors of chronic suppurative otitis media among rural primary school children of Bangladesh. (22652497)
2012
4
Comparison of the effectiveness and safety of cefpodoxime and ciprofloxacin in acute exacerbation of chronic suppurative otitis media: A randomized, open-labeled, phase IV clinical trial. (23326103)
2012
5
Chronic suppurative otitis media in Nepal: ethnicity does not determine whether disease is associated with cholesteatoma or not. (20875194)
2011
6
Aetiological agents in chronic suppurative otitis media in Sri Lanka. (23386888)
2011
7
Observation of hearing loss in patients with chronic suppurative otitis media tubotympanic type. (20502081)
2009
8
The role of retinol in the etiology and outcome of suppurative otitis media. (18704470)
2009
9
Efficacy of tympanoplasty without mastoidectomy for chronic suppurative otitis media. (19015443)
2008
10
Chronic suppurative otitis media. (16973034)
2006
11
Antibiotics for the prevention of acute and chronic suppurative otitis media in children. (17054203)
2006
12
Bacteriological study of paediatric and adult chronic suppurative otitis media. (16761774)
2005
13
Ciprofloxacin in the treatment of chronic suppurative otitis media. (15257644)
2004
14
Chronic suppurative otitis media. (15865672)
2004
15
Ciliary count in chronic suppurative otitis media: comparative quantitative study between mucosal and squamous types using scanning electron microscopy and image analysis. (15165307)
2004
16
Chronic suppurative otitis media and sensorineural hearing loss: Is there a correlation? (23119929)
2003
17
Evaluation of topical povidone-iodine in chronic suppurative otitis media. (14568795)
2003
18
Cochlear implantation in chronic suppurative otitis media. (11773847)
2002
19
Treatment of chronic suppurative otitis media with ofloxacin in hydroxypropyl methylcellulose ear drops: a clinical/bacteriological study in a rural area of Malawi. (11879929)
2002
20
Topical and systemic treatment for chronic suppurative otitis media. (12199182)
2002
21
Chronic suppurative otitis media: a clinical overview. (12199189)
2002
22
Efficacy of ofloxacin and other ototopical preparations for chronic suppurative otitis media in children. (11176589)
2001
23
Correlation of pure tone audiogram results and hearing benefit of tympanoplasty for chronic suppurative otitis media. (10778893)
2000
24
Burow's solution in the treatment of active mucosal chronic suppurative otitis media: determining an effective dilution. (10962675)
2000
25
Chronic suppurative otitis media: prevalence and practices among rural South Indian children. (10402118)
1999
26
A new dosage regimen for topical application of ciprofloxacin in the management of chronic suppurative otitis media. (9627259)
1998
27
A double-blind comparative study of ofloxacin otic drops versus neomycin-polymyxin B-hydrocortisone otic drops in the medical treatment of chronic suppurative otitis media. (8733449)
1996
28
Classification of chronic suppurative otitis media: type IV. (8942081)
1996
29
Burkholderia (Pseudomonas) cepacia as a cause of brain abscesses secondary to chronic suppurative otitis media. (8605906)
1995
30
Chronic bilateral suppurative otitis media caused by Aspergillus terreus. (8559193)
1995
31
Cerebellar venous infarction in chronic suppurative otitis media. A case report with review of four other cases. (8165678)
1994
32
Acute suppurative otitis media. (8344177)
1993
33
Medical management of chronic suppurative otitis media without cholesteatoma in children--update 1992. (8122710)
1993
34
Medical treatment of chronic suppurative otitis media without cholesteatoma in children--a two-year follow-up. (1399301)
1992
35
Aerobic bacteriology of chronic suppurative otitis media without cholesteatoma in children. (1416643)
1992
36
Medical management of chronic suppurative otitis media without cholesteatoma in children. (2189979)
1990
37
Non-suppurative otitis media. (3235847)
1988
38
Relationship between acute suppurative otitis media and chronic secretory otitis media: role of antibiotics. (6332914)
1984
39
Antibiotics in suppurative otitis media. (854351)
1977
40
Bacteriology and antibiotics in acute suppurative otitis media. (9519)
1976
41
Current management of chronic suppurative otitis media. (5727857)
1968
42
Treatment of chronic suppurative otitis media. (20328551)
1966
43
Displacement therapy in chronic suppurative otitis media. (14779103)
1950
44
Lempert endaural subcortical mastoidotympanectomy for the cure of chronic persistent suppurative otitis media. (18110051)
1949
45
Operative treatment of chronic suppurative otitis media. (15394259)
1949
46
Facial palsy accompanying acute suppurative otitis media. (21001504)
1946
47
SOME REMARKS ON CHRONIC SUPPURATIVE OTITIS MEDIA ITS PREVENTION AND TREATMENT. (20318435)
1931
48
Two Cases of Chronic Suppurative Otitis Media, treated by Ionization. (19983901)
1924
49
Three Cases of Chronic Suppurative Otitis Media. (19976234)
1912
50
Temporo-sphenoidal Abscess following Chronic Suppurative Otitis Media; Operation; Death. (19976263)
1912

Genetic Variations for Suppurative Otitis Media

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Expression for genes affiliated with Suppurative Otitis Media

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Suppurative Otitis Media

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Pathways for genes affiliated with Suppurative Otitis Media

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Compounds for genes affiliated with Suppurative Otitis Media

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Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 24HMDB, 28IUPHAR, 2BitterDB
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Compounds related to Suppurative Otitis Media according to GeneCards/GeneDecks:

(show all 15)
idCompoundScoreTop Affiliating Genes
1gabexate mesilate449.3SERPINC1, CRP
2tirofiban44 1110.3SERPINC1, CRP
3tibolone449.3SERPINC1, CRP
4abciximab44 1110.3CRP, SERPINC1
5clopidogrel49 44 11 2412.3SERPINC1, CRP
6polyethylene glycol449.3SERPINC1, CRP
7homocysteine44 2410.2SERPINC1, CRP
8citrate449.2CRP, SERPINC1
9folate449.2SERPINC1, CRP
10prostacyclin449.1SERPINC1, CRP
11aspirin44 49 28 2412.1SERPINC1, CRP
12chloramphenicol44 2 1111.0CRP, SERPINC1
13fibrinogen449.0SERPINC1, CRP
14n acetylcysteine448.9SERPINC1, CRP
15ascorbic acid44 249.7SERPINC1, CRP

GO Terms for genes affiliated with Suppurative Otitis Media

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Products for genes affiliated with Suppurative Otitis Media

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  • Antibodies
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Sources for Suppurative Otitis Media

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet