MCID: SPP008
MIFTS: 41

Suppurative Otitis Media malady

Ear diseases category
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Summaries for Suppurative Otitis Media

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8Disease Ontology, 33MalaCards
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Disease Ontology:8 A otitis media which involves inflammation of the middle ear with infected effusion containing pus.

MalaCards: Suppurative Otitis Media, also known as suppurative and unspecified otitis media, is related to otitis media and cholesteatoma. An important gene associated with Suppurative Otitis Media is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1). The compounds gabexate mesilate and tirofiban have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and testes.

Aliases & Classifications for Suppurative Otitis Media

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Sources:
8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 27ICD9CM, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

suppurative otitis media 8 10 62
suppurative and unspecified otitis media 8
suppurative otitis media &/or left 8
otitis media with effusion - purulent 8
right &/or purulent otitis media 8
unspecified suppurative otitis media 8
purulent otitis media nos 8
suppurative otitis med. 8
infection - suppurative 62
purulent otitis media 8


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Disease Ontology8 DOID:11506
ICD9CM27 382, 382.4
MeSH35 D010035
ICD1025 H66

Related Diseases for Suppurative Otitis Media

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Suppurative Otitis Media:



Diseases related to suppurative otitis media

Symptoms for Suppurative Otitis Media

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Drugs & Therapeutics for Suppurative Otitis Media

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Suppurative Otitis Media

Search NIH Clinical Center for Suppurative Otitis Media

Genetic Tests for Suppurative Otitis Media

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Anatomical Context for Suppurative Otitis Media

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33MalaCards
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MalaCards organs/tissues related to Suppurative Otitis Media:

33
Bone, Brain, Testes, Temporal lobe

Animal Models for Suppurative Otitis Media or affiliated genes

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Publications for Suppurative Otitis Media

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52PubMed
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Articles related to Suppurative Otitis Media:

(show top 50)    (show all 485)
idTitleAuthorsYear
1
Microbiology of chronic suppurative otitis media in a tertiary care setup of uttarakhand state, India. (23724403)
2013
2
Computed tomography in chronic suppurative otitis media: value in surgical planning. (23998024)
2012
3
Chronic suppurative otitis media in Nepal: ethnicity does not determine whether disease is associated with cholesteatoma or not. (20875194)
2011
4
Biofilms in chronic suppurative otitis media and cholesteatoma: scanning electron microscopy findings. (20036033)
2011
5
Sarcoidosis of the middle ear and chronic suppurative otitis media: coexisting conditions? (21307811)
2011
6
Chronic suppurative otitis media, caloric testing, and rotational chair testing. (18046261)
2008
7
The role of anaerobic bacteria in chronic suppurative otitis media in children: implications for medical therapy. (19114112)
2008
8
Chronic suppurative otitis media: a review. (16198004)
2006
9
Chronic suppurative otitis media. (16973034)
2006
10
Topical quinolone vs. antiseptic for treating chronic suppurative otitis media: a randomized controlled trial. (15839875)
2005
11
Meningitis with bilateral acute suppurative otitis media caused by Group A streptococcus. (15695870)
2005
12
Mucosal biofilm formation on middle-ear mucosa in a nonhuman primate model of chronic suppurative otitis media. (16094127)
2005
13
Bacteriological study of paediatric and adult chronic suppurative otitis media. (16761774)
2005
14
Intracranial abscesses associated with chronic suppurative otitis media. (15959795)
2005
15
Emergence of ciprofloxacin-resistant pseudomonas in chronic suppurative otitis media. (15270816)
2004
16
Subjective evaluation and overall satisfaction after tympanoplasty for chronic simple suppurative otitis media. (15129591)
2004
17
Type V chronic suppurative otitis media. (10893828)
2000
18
Comparison of ofloxacin otic solution with oral amoxycillin plus chloramphenicol ear drop in treatment of chronic suppurative otitis media with acute exacerbation. (10710871)
2000
19
Chronic suppurative otitis media in a children's hospital in Addis Ababa, Ethiopia. (11961874)
1999
20
Clinical trial of ototopical ofloxacin for treatment of chronic suppurative otitis media. (9737834)
1998
21
Anaerobes and fungi in chronic suppurative otitis media. (9270427)
1997
22
Classification of chronic suppurative otitis media: type III. (8870360)
1996
23
Classification of chronic suppurative otitis media: type II. (8828267)
1996
24
Use of pre-reduced swabs in bacteriology of chronic suppurative otitis media. (8977860)
1996
25
Epidemiology of chronic suppurative otitis media and deafness in a rural area and developing an intervention strategy. (10829951)
1995
26
Burkholderia (Pseudomonas) cepacia as a cause of brain abscesses secondary to chronic suppurative otitis media. (8605906)
1995
27
Cochlear implants in chronic suppurative otitis media. (8588677)
1995
28
Chronic suppurative otitis media without cholesteatoma management. (8630764)
1995
29
Microbiology of chronic suppurative otitis media in children in Surabaya, Indonesia. (7729990)
1995
30
Chronic suppurative otitis media. (7803887)
1994
31
Therapeutic management of chronic suppurative otitis media with otic drops. (8393167)
1993
32
Chronic suppurative otitis media in Sudanese patients. (2354676)
1990
33
The early signs and symptoms of neurotologic complications of chronic suppurative otitis media. (2927213)
1989
34
Radiology in the management of chronic suppurative otitis media. (7236161)
1980
35
Analysis of suppurative otitis media in children: aetiology of non-suppurative otitis media. (1152752)
1975
36
Developmental variations of the temporal bone that influence the evolution of chronic suppurative otitis media and mastoiditis and the medical and surgical treatment of this syndrome. (4890239)
1969
37
The use of oestrogens in chronic suppurative otitis media. Report of two cases. (5796438)
1969
38
Treatment of chronic suppurative otitis media. (20328551)
1966
39
LATENT BRAIN ABSCESSES WHICH MANIFEST THEMSELVES AFTER MASTOIDECTOMY IN CHRONIC SUPPURATIVE OTITIS MEDIA. (14270832)
1964
40
Acute suppurative otitis media. (14825017)
1951
41
Acute exacerbation, chronic suppurative otitis media, left, with temporo-sphenoidal abscess. (18892970)
1948
42
A study of chronic suppurative otitis media at the Pennsylvania School for the Deaf. (21023139)
1946
43
Chronic Suppurative Otitis Media. Modified Radical Operation. (19991399)
1938
44
Chronic Suppurative Otitis Media. (20779844)
1936
45
Streptococcal Meningitis secondary to Acute Suppurative Otitis Media: Simple Mastoidectomy. Recovery. (19990217)
1935
46
Acute Exacerbation of Chronic Suppurative Otitis Media. Extradural Abscess. Complete Hemianopia. (19990096)
1935
47
SOME REMARKS ON CHRONIC SUPPURATIVE OTITIS MEDIA ITS PREVENTION AND TREATMENT. (20318435)
1931
48
Case of Traumatic Destruction of Labyrinth on the Left Side with Hysterical Deafness and Chronic Suppurative Otitis Media on the Right Side. (19986528)
1928
49
Chronic Suppurative Otitis-Media with a Fistula of the External Semi-Circular Canal. (20315106)
1924
50
Tuberculous (?) Septic (?) Meningitis following Chronic Suppurative Otitis Media; Operation; Repeated Lumbar Punctures; Prolonged Illness; Recovery. (19979388)
1916

Variations for Suppurative Otitis Media

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Expression for genes affiliated with Suppurative Otitis Media

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Suppurative Otitis Media

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Pathways for genes affiliated with Suppurative Otitis Media

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Compounds for genes affiliated with Suppurative Otitis Media

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45Novoseek, 11DrugBank, 51PharmGKB, 24HMDB, 29IUPHAR, 3BitterDB, 61Tocris Bioscience
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Compounds related to Suppurative Otitis Media according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1gabexate mesilate459.4CRP, SERPINC1
2tirofiban45 1110.3CRP, SERPINC1
3tibolone459.3CRP, SERPINC1
4abciximab45 1110.3CRP, SERPINC1
5clopidogrel45 51 24 1112.3SERPINC1, CRP
6polyethylene glycol459.3CRP, SERPINC1
7homocysteine45 2410.3CRP, SERPINC1
8citrate459.3SERPINC1, CRP
9folate459.3CRP, SERPINC1
10prostacyclin459.2SERPINC1, CRP
11aspirin45 51 29 2412.2CRP, SERPINC1
12chloramphenicol45 3 51 1112.2CRP, SERPINC1
13n acetylcysteine459.1CRP, SERPINC1
14ascorbic acid45 2410.1SERPINC1, CRP
15fibrinogen459.0CRP, SERPINC1
16vegf459.0CRP, SERPINC1
17creatinine458.9CRP, SERPINC1
18testosterone45 61 24 1111.7CRP, SERPINC1

GO Terms for genes affiliated with Suppurative Otitis Media

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Products for genes affiliated with Suppurative Otitis Media

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Sources for Suppurative Otitis Media

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet