MCID: SPP008
MIFTS: 41

Suppurative Otitis Media malady

Ear diseases category

Summaries for Suppurative Otitis Media

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9Disease Ontology, 34MalaCards
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Disease Ontology:9 A otitis media which involves inflammation of the middle ear with infected effusion containing pus.

MalaCards: Suppurative Otitis Media, also known as suppurative and unspecified otitis media, is related to otitis media and cholesteatoma. An important gene associated with Suppurative Otitis Media is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1). The compounds gabexate mesilate and tirofiban have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and testes.

Aliases & Classifications for Suppurative Otitis Media

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

suppurative otitis media 9 11 63
suppurative and unspecified otitis media 9
suppurative otitis media &/or left 9
otitis media with effusion - purulent 9
right &/or purulent otitis media 9
unspecified suppurative otitis media 9
purulent otitis media nos 9
suppurative otitis med. 9
infection - suppurative 63
purulent otitis media 9


External Ids:

Disease Ontology9 DOID:11506
ICD9CM28 382, 382.4
MeSH36 D010035
ICD1026 H66

Related Diseases for Suppurative Otitis Media

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Suppurative Otitis Media:



Diseases related to suppurative otitis media

Symptoms for Suppurative Otitis Media

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Drugs & Therapeutics for Suppurative Otitis Media

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Suppurative Otitis Media

Drug clinical trials:

Search ClinicalTrials for Suppurative Otitis Media

Search NIH Clinical Center for Suppurative Otitis Media

Search CenterWatch for Suppurative Otitis Media

Genetic Tests for Suppurative Otitis Media

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Anatomical Context for Suppurative Otitis Media

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34MalaCards
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MalaCards organs/tissues related to Suppurative Otitis Media:

34
Bone, Brain, Testes, Temporal lobe

Animal Models for Suppurative Otitis Media or affiliated genes

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Publications for Suppurative Otitis Media

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Sources:
53PubMed
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Articles related to Suppurative Otitis Media:

(show top 50)    (show all 485)
idTitleAuthorsYear
1
Microbiology of chronic suppurative otitis media in a tertiary care setup of uttarakhand state, India. (23724403)
2013
2
Computed tomography in chronic suppurative otitis media: value in surgical planning. (23998024)
2012
3
Chronic suppurative otitis media in Nepal: ethnicity does not determine whether disease is associated with cholesteatoma or not. (20875194)
2011
4
Biofilms in chronic suppurative otitis media and cholesteatoma: scanning electron microscopy findings. (20036033)
2011
5
Sarcoidosis of the middle ear and chronic suppurative otitis media: coexisting conditions? (21307811)
2011
6
Chronic suppurative otitis media, caloric testing, and rotational chair testing. (18046261)
2008
7
The role of anaerobic bacteria in chronic suppurative otitis media in children: implications for medical therapy. (19114112)
2008
8
Chronic suppurative otitis media: a review. (16198004)
2006
9
Chronic suppurative otitis media. (16973034)
2006
10
Topical quinolone vs. antiseptic for treating chronic suppurative otitis media: a randomized controlled trial. (15839875)
2005
11
Meningitis with bilateral acute suppurative otitis media caused by Group A streptococcus. (15695870)
2005
12
Mucosal biofilm formation on middle-ear mucosa in a nonhuman primate model of chronic suppurative otitis media. (16094127)
2005
13
Bacteriological study of paediatric and adult chronic suppurative otitis media. (16761774)
2005
14
Intracranial abscesses associated with chronic suppurative otitis media. (15959795)
2005
15
Emergence of ciprofloxacin-resistant pseudomonas in chronic suppurative otitis media. (15270816)
2004
16
Subjective evaluation and overall satisfaction after tympanoplasty for chronic simple suppurative otitis media. (15129591)
2004
17
Type V chronic suppurative otitis media. (10893828)
2000
18
Comparison of ofloxacin otic solution with oral amoxycillin plus chloramphenicol ear drop in treatment of chronic suppurative otitis media with acute exacerbation. (10710871)
2000
19
Chronic suppurative otitis media in a children's hospital in Addis Ababa, Ethiopia. (11961874)
1999
20
Clinical trial of ototopical ofloxacin for treatment of chronic suppurative otitis media. (9737834)
1998
21
Anaerobes and fungi in chronic suppurative otitis media. (9270427)
1997
22
Classification of chronic suppurative otitis media: type III. (8870360)
1996
23
Classification of chronic suppurative otitis media: type II. (8828267)
1996
24
Use of pre-reduced swabs in bacteriology of chronic suppurative otitis media. (8977860)
1996
25
Epidemiology of chronic suppurative otitis media and deafness in a rural area and developing an intervention strategy. (10829951)
1995
26
Burkholderia (Pseudomonas) cepacia as a cause of brain abscesses secondary to chronic suppurative otitis media. (8605906)
1995
27
Cochlear implants in chronic suppurative otitis media. (8588677)
1995
28
Chronic suppurative otitis media without cholesteatoma management. (8630764)
1995
29
Microbiology of chronic suppurative otitis media in children in Surabaya, Indonesia. (7729990)
1995
30
Chronic suppurative otitis media. (7803887)
1994
31
Therapeutic management of chronic suppurative otitis media with otic drops. (8393167)
1993
32
Chronic suppurative otitis media in Sudanese patients. (2354676)
1990
33
The early signs and symptoms of neurotologic complications of chronic suppurative otitis media. (2927213)
1989
34
Radiology in the management of chronic suppurative otitis media. (7236161)
1980
35
Analysis of suppurative otitis media in children: aetiology of non-suppurative otitis media. (1152752)
1975
36
Developmental variations of the temporal bone that influence the evolution of chronic suppurative otitis media and mastoiditis and the medical and surgical treatment of this syndrome. (4890239)
1969
37
The use of oestrogens in chronic suppurative otitis media. Report of two cases. (5796438)
1969
38
Treatment of chronic suppurative otitis media. (20328551)
1966
39
LATENT BRAIN ABSCESSES WHICH MANIFEST THEMSELVES AFTER MASTOIDECTOMY IN CHRONIC SUPPURATIVE OTITIS MEDIA. (14270832)
1964
40
Acute suppurative otitis media. (14825017)
1951
41
Acute exacerbation, chronic suppurative otitis media, left, with temporo-sphenoidal abscess. (18892970)
1948
42
A study of chronic suppurative otitis media at the Pennsylvania School for the Deaf. (21023139)
1946
43
Chronic Suppurative Otitis Media. Modified Radical Operation. (19991399)
1938
44
Chronic Suppurative Otitis Media. (20779844)
1936
45
Streptococcal Meningitis secondary to Acute Suppurative Otitis Media: Simple Mastoidectomy. Recovery. (19990217)
1935
46
Acute Exacerbation of Chronic Suppurative Otitis Media. Extradural Abscess. Complete Hemianopia. (19990096)
1935
47
SOME REMARKS ON CHRONIC SUPPURATIVE OTITIS MEDIA ITS PREVENTION AND TREATMENT. (20318435)
1931
48
Case of Traumatic Destruction of Labyrinth on the Left Side with Hysterical Deafness and Chronic Suppurative Otitis Media on the Right Side. (19986528)
1928
49
Chronic Suppurative Otitis-Media with a Fistula of the External Semi-Circular Canal. (20315106)
1924
50
Tuberculous (?) Septic (?) Meningitis following Chronic Suppurative Otitis Media; Operation; Repeated Lumbar Punctures; Prolonged Illness; Recovery. (19979388)
1916

Variations for Suppurative Otitis Media

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Expression for genes affiliated with Suppurative Otitis Media

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Suppurative Otitis Media

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Pathways for genes affiliated with Suppurative Otitis Media

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Compounds for genes affiliated with Suppurative Otitis Media

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Sources:
46Novoseek, 12DrugBank, 52PharmGKB, 25HMDB, 30IUPHAR, 3BitterDB, 62Tocris Bioscience
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Compounds related to Suppurative Otitis Media according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1gabexate mesilate469.4CRP, SERPINC1
2tirofiban46 1210.3CRP, SERPINC1
3tibolone469.3CRP, SERPINC1
4abciximab46 1210.3CRP, SERPINC1
5clopidogrel46 52 25 1212.3SERPINC1, CRP
6polyethylene glycol469.3CRP, SERPINC1
7homocysteine46 2510.3CRP, SERPINC1
8citrate469.3SERPINC1, CRP
9folate469.3CRP, SERPINC1
10prostacyclin469.2SERPINC1, CRP
11aspirin46 52 30 2512.2CRP, SERPINC1
12chloramphenicol46 3 52 1212.2CRP, SERPINC1
13n acetylcysteine469.1CRP, SERPINC1
14ascorbic acid46 2510.1SERPINC1, CRP
15fibrinogen469.0CRP, SERPINC1
16vegf469.0CRP, SERPINC1
17creatinine468.9CRP, SERPINC1
18testosterone46 62 25 1211.7CRP, SERPINC1

GO Terms for genes affiliated with Suppurative Otitis Media

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Products for genes affiliated with Suppurative Otitis Media

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  • Antibodies
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Sources for Suppurative Otitis Media

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet