MCID: SPP008
MIFTS: 40

Suppurative Otitis Media malady

Ear diseases category

Summaries for Suppurative Otitis Media

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A otitis media which involves inflammation of the middle ear with infected effusion containing pus.

MalaCards: Suppurative Otitis Media, also known as suppurative and unspecified otitis media, is related to otitis media and cholesteatoma. An important gene associated with Suppurative Otitis Media is SERPINC1 (serpin peptidase inhibitor, clade C (antithrombin), member 1). The compounds gabexate mesilate and tirofiban have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and testes.

Aliases & Classifications for Suppurative Otitis Media

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


Aliases & Descriptions:

suppurative otitis media 8 10 60
suppurative and unspecified otitis media 8
suppurative otitis media &/or left 8
otitis media with effusion - purulent 8
right &/or purulent otitis media 8
unspecified suppurative otitis media 8
purulent otitis media nos 8
infection - suppurative 60
suppurative otitis med. 8
purulent otitis media 8


External Ids:

Disease Ontology8 DOID:11506
MeSH34 D010035
ICD9CM27 382, 382.4
ICD1025 H66

Related Diseases for Suppurative Otitis Media

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Suppurative Otitis Media:



Diseases related to suppurative otitis media

Clinical Features for Suppurative Otitis Media

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Drugs & Therapeutics for Suppurative Otitis Media

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Suppurative Otitis Media

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Anatomical Context for Suppurative Otitis Media

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32MalaCards
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MalaCards organs/tissues related to Suppurative Otitis Media:

32
Bone, Brain, Testes, Temporal lobe

Animal Models for Suppurative Otitis Media or affiliated genes

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Publications for Suppurative Otitis Media

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50PubMed
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Articles related to Suppurative Otitis Media:

(show top 50)    (show all 488)
idTitleAuthorsYear
1
Co-morbidities in Children Presenting with Chronic Suppurative Otitis Media--A South African Study. (24401753)
2014
2
The role of readability in effective health communication: an experiment using a Japanese health information text on chronic suppurative otitis media. (23981023)
2013
3
Computed tomography in chronic suppurative otitis media: value in surgical planning. (23998024)
2012
4
Rarely reported ocular complications following surgery to correct chronic suppurative otitis media. (21626122)
2012
5
Ossicular chain status in chronic suppurative otitis media in adults. (22319706)
2010
6
The Bortnick Miller apparatus: a useful alternative to impedance audiometer for assessment of eustachian tube function in chronic suppurative otitis media. (23120621)
2009
7
The role of anaerobic bacteria in chronic suppurative otitis media in children: implications for medical therapy. (19114112)
2008
8
Acute suppurative otitis media. (18572776)
2008
9
Clinico-epidemiological study of complicated and uncomplicated chronic suppurative otitis media. (17666139)
2008
10
The prevalence of hearing loss among schoolchildren with chronic suppurative otitis media in Nigeria, and its effect on academic performance. (19105130)
2008
11
Clinical and demographic risk factors associated with chronic suppurative otitis media. (17643499)
2007
12
Socio-economic status and hearing loss in chronic suppurative otitis media in Nigeria. (18053346)
2007
13
Effect of climate on the bacteriology of chronic suppurative otitis media. (16190100)
2005
14
Microbiology and drug sensitivity patterns of chronic suppurative otitis media. (15321034)
2004
15
Mycoplasma bovis-associated suppurative otitis media and pneumonia in bull calves. (12921715)
2003
16
Epidemiology of chronic suppurative otitis media among Saudi children--a comparative study of two decades. (11852123)
2002
17
Topical quinolones in the treatment of chronic suppurative otitis media and recurrent otorrhea. (12199184)
2002
18
Type V chronic suppurative otitis media. (10893828)
2000
19
Comparison of ofloxacin otic solution with oral amoxycillin plus chloramphenicol ear drop in treatment of chronic suppurative otitis media with acute exacerbation. (10710871)
2000
20
Clinicomicrobiologic evaluation of active tubotympanic type chronic suppurative otitis media. (10883827)
2000
21
Ceftazidime for outpatient parenteral antibiotic therapy (OPAT) of chronic suppurative otitis media due to Pseudomonas aeruginosa. (10768520)
2000
22
Fungal and bacterial flora of chronic suppurative otitis media in amritsar (punjab). (23119409)
1998
23
A profile of 100 complicated cases of chronic suppurative otitis media. (9195829)
1997
24
Mastoidectomy in noncholesteatomatous chronic suppurative otitis media: is it necessary? (9419084)
1997
25
Use of pre-reduced swabs in bacteriology of chronic suppurative otitis media. (8977860)
1996
26
Bacteriological patterns of chronic suppurative otitis media in Ludhiana. (8979528)
1996
27
Cochlear implants in chronic suppurative otitis media. (8588677)
1995
28
Bacteriology of chronic suppurative otitis media. (7944167)
1994
29
The cellular mechanism of ossicular erosion in chronic suppurative otitis media. (8445302)
1993
30
Extracranial and intracranial complications of suppurative otitis media. Report of 102 cases. (8288994)
1993
31
Immunoglobulin-coated bacteria in effusions from secretory and chronic suppurative otitis media. (1928600)
1991
32
Current management of chronic suppurative otitis media in infants and children. (3217177)
1988
33
Microbiology of chronic suppurative otitis media in children. (3081881)
1986
34
Anaerobes in chronic suppurative otitis media. (7287104)
1981
35
The bacterial etiology of acute suppurative otitis media. (7373121)
1980
36
Anaerobic isolates in chronic recurrent suppurative otitis media. Treatment with carbenicillin alone and in combination with gentamicin. (41811)
1979
37
Tubing, as a treatment for recurrent infant suppurative otitis media. (1059313)
1975
38
Complications of chronic suppurative otitis media in Chiang Mai, Thailand. (4636840)
1972
39
ETIOLOGY OF CHRONIC SUPPURATIVE OTITIS MEDIA. (14051405)
1963
40
Studies on the effect of penicillin intramuscularly and orally in acute suppurative otitis media in children. (13748036)
1960
41
The surgery of the ear in the management of intracranial complications of chronic suppurative otitis media. (13252333)
1955
42
Dangers inherent in the nonsurgical concept of acute suppurative otitis media. (14362329)
1955
43
Chronic suppurative otitis media; study of sensitivity to antibiotics of bacteria commonly found in chronic otitis media. (13180064)
1954
44
A case of acute suppurative otitis media with tardy occurrence of perisinuous abscess and thrombosis of the sigmoid sinus. (21006614)
1945
45
ZINC IONIZATION IN THE TREATMENT OF SUPPURATIVE OTITIS MEDIA. (20773202)
1927
46
Streptococcal Leptomeningitis in a Child due to Chronic Suppurative Otitis Media; Rapid Development of Coma; Radical Mastoid Operation with Translabyrinthine and Lumbar Thecal Drainage, with Complete Recovery. (19981917)
1921
47
Chronic Osteomyelitis of the Labyrinth Capsule (Paralabyrinthitis) in Suppurative Otitis Media. (19979399)
1916
48
Res Judicatae: The Conservative Treatment of Suppurative Otitis Media. (20310303)
1912
49
The Predisposing Cause of Chronic Suppurative Otitis Media. (18734783)
1909
50
Primary Epithelioma (?) of Tympanum following Chronic Suppurative Otitis media. (19973285)
1908

Genetic Variations for Suppurative Otitis Media

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Expression for genes affiliated with Suppurative Otitis Media

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Suppurative Otitis Media

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Pathways for genes affiliated with Suppurative Otitis Media

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Compounds for genes affiliated with Suppurative Otitis Media

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Sources:
44Novoseek, 11DrugBank, 49PharmGKB, 24HMDB, 28IUPHAR, 2BitterDB
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Compounds related to Suppurative Otitis Media according to GeneCards/GeneDecks:

(show all 15)
idCompoundScoreTop Affiliating Genes
1gabexate mesilate449.3SERPINC1, CRP
2tirofiban44 1110.3SERPINC1, CRP
3tibolone449.3SERPINC1, CRP
4abciximab44 1110.3CRP, SERPINC1
5clopidogrel49 44 11 2412.3SERPINC1, CRP
6polyethylene glycol449.3SERPINC1, CRP
7homocysteine44 2410.2SERPINC1, CRP
8citrate449.2CRP, SERPINC1
9folate449.2SERPINC1, CRP
10prostacyclin449.1SERPINC1, CRP
11aspirin44 49 28 2412.1SERPINC1, CRP
12chloramphenicol44 2 1111.0CRP, SERPINC1
13fibrinogen449.0SERPINC1, CRP
14n acetylcysteine448.9SERPINC1, CRP
15ascorbic acid44 249.7SERPINC1, CRP

GO Terms for genes affiliated with Suppurative Otitis Media

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Products for genes affiliated with Suppurative Otitis Media

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  • Antibodies
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Sources for Suppurative Otitis Media

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet