MCID: SPR100
MIFTS: 19

Supranuclear Palsy, Progressive Atypical malady

Genetic diseases, Rare diseases, Neuronal diseases, Eye diseases, Mental diseases categories

Aliases & Classifications for Supranuclear Palsy, Progressive Atypical

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Sources:
46OMIM, 9diseasecard, 42NIH Rare Diseases, 48Orphanet, 61UMLS, 34MESH via Orphanet, 26ICD10 via Orphanet, 62UMLS via Orphanet
See all sources

Aliases & Descriptions for Supranuclear Palsy, Progressive Atypical:

Name: Supranuclear Palsy, Progressive Atypical 46 9
Atypical Psp 42 48
Parkinson-Dementia Syndrome Supranuclear Palsy, Progressive, 1, Atypical, Included 46
 
Supranuclear Palsy, Progressive, 1, Atypical 61
Atypical Progressive Supranuclear Palsy 48
Progressive Supranuclear Palsy Atypical 42


Classifications:



Characteristics (Orphanet epidemiological data):

48
atypical psp:
Prevalence: 1-9/100000 (Europe)


External Ids:

OMIM46 260540
Orphanet48 99750
MESH via Orphanet34 C537240
ICD10 via Orphanet26 G23.1
UMLS via Orphanet62 C1850077

Summaries for Supranuclear Palsy, Progressive Atypical

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MalaCards based summary: Supranuclear Palsy, Progressive Atypical, also known as atypical psp, is related to supranuclear palsy, progressive and lateral sclerosis, and has symptoms including ophthalmoparesis, dementia and parkinsonism. An important gene associated with Supranuclear Palsy, Progressive Atypical is MAPT (microtubule-associated protein tau). Affiliated tissues include eye.

Description from OMIM:46 260540

Related Diseases for Supranuclear Palsy, Progressive Atypical

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Diseases related to Supranuclear Palsy, Progressive Atypical via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1supranuclear palsy, progressive10.3
2lateral sclerosis10.3
3aphasia10.3
4apraxia10.3

Symptoms for Supranuclear Palsy, Progressive Atypical

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Symptoms by clinical synopsis from OMIM:

260540

Clinical features from OMIM:

260540

HPO human phenotypes related to Supranuclear Palsy, Progressive Atypical:

(show all 8)
id Description Frequency HPO Source Accession
1 ophthalmoparesis HP:0000597
2 dementia HP:0000726
3 parkinsonism HP:0001300
4 tremor HP:0001337
5 morphological abnormality of the pyramidal tract HP:0002062
6 rigidity HP:0002063
7 kyphoscoliosis HP:0002751
8 adult onset HP:0003581

Drugs & Therapeutics for Supranuclear Palsy, Progressive Atypical

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Drug clinical trials:

Search ClinicalTrials for Supranuclear Palsy, Progressive Atypical

Search NIH Clinical Center for Supranuclear Palsy, Progressive Atypical

Genetic Tests for Supranuclear Palsy, Progressive Atypical

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Anatomical Context for Supranuclear Palsy, Progressive Atypical

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MalaCards organs/tissues related to Supranuclear Palsy, Progressive Atypical:

31
Eye

Animal Models for Supranuclear Palsy, Progressive Atypical or affiliated genes

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Publications for Supranuclear Palsy, Progressive Atypical

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Variations for Supranuclear Palsy, Progressive Atypical

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Expression for genes affiliated with Supranuclear Palsy, Progressive Atypical

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Search GEO for disease gene expression data for Supranuclear Palsy, Progressive Atypical.

Pathways for genes affiliated with Supranuclear Palsy, Progressive Atypical

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Compounds for genes affiliated with Supranuclear Palsy, Progressive Atypical

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GO Terms for genes affiliated with Supranuclear Palsy, Progressive Atypical

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Sources for Supranuclear Palsy, Progressive Atypical

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet