MCID: SPR008
MIFTS: 44

Supratentorial Primitive Neuroectodermal Tumor

Categories: Rare diseases, Cancer diseases, Neuronal diseases

Aliases & Classifications for Supratentorial Primitive Neuroectodermal Tumor

MalaCards integrated aliases for Supratentorial Primitive Neuroectodermal Tumor:

Name: Supratentorial Primitive Neuroectodermal Tumor 12 49 14 69
Ewings Sarcoma-Primitive Neuroectodermal Tumor 69
Peripheral Neuroectodermal Tumor 49
Primative Neuroectodermal Tumor 49
Supratentorial Pnet 12
Pnet 49

Classifications:



External Ids:

Disease Ontology 12 DOID:4791
NCIt 46 C6968
SNOMED-CT 64 39781001 699318007
UMLS 69 C1336538

Summaries for Supratentorial Primitive Neuroectodermal Tumor

MalaCards based summary : Supratentorial Primitive Neuroectodermal Tumor, also known as ewings sarcoma-primitive neuroectodermal tumor, is related to merkel cell carcinoma and supratentorial primitive neuroectodermal tumors, childhood, and has symptoms including fever An important gene associated with Supratentorial Primitive Neuroectodermal Tumor is SYP (Synaptophysin), and among its related pathways/superpathways are Neuroscience and Tyrosine metabolism. The drugs Afinitor and Sutent have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and endothelial.

Related Diseases for Supratentorial Primitive Neuroectodermal Tumor

Diseases related to Supratentorial Primitive Neuroectodermal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Related Disease Score Top Affiliating Genes
1 merkel cell carcinoma 29.5 NCAM1 SYP
2 supratentorial primitive neuroectodermal tumors, childhood 12.4
3 primitive neuroectodermal tumor of the cervix uteri 11.3
4 soft tissue peripheral neuroepithelioma 11.1
5 primitive neuroectodermal tumor of the corpus uteri 11.1
6 medulloblastoma 10.6
7 esophageal neuroendocrine tumor 10.4 NCAM1 SYP
8 ovarian large-cell neuroendocrine carcinoma 10.4 NCAM1 SYP
9 lung combined type small cell carcinoma 10.4 NCAM1 SYP
10 cutaneous ganglioneuroma 10.4 NCAM1 SYP
11 gallbladder small cell carcinoma 10.4 NCAM1 SYP
12 extrahepatic bile duct adenocarcinoma 10.4 NCAM1 SYP
13 orbital cancer 10.4 NCAM1 SYP
14 pancreatic endocrine carcinoma 10.4 NCAM1 SYP
15 pancreatic serous cystadenoma 10.4 NCAM1 SYP
16 conventional angiosarcoma 10.4 NCAM1 SYP
17 endometrial small cell carcinoma 10.4 NCAM1 SYP
18 mediastinal cancer 10.4 NCAM1 SYP
19 subependymoma 10.4 NCAM1 SYP
20 primary hepatic neuroendocrine carcinoma 10.3 S100B SYP
21 angiomyoma 10.3 NCAM1 SYP
22 gastric squamous cell carcinoma 10.3 NCAM1 SYP
23 gastric small cell carcinoma 10.3 NCAM1 SYP
24 mixed type thymoma 10.3 S100B SYP
25 chordoid meningioma 10.3 S100B SYP
26 small cell neuroendocrine carcinoma 10.3 NCAM1 SYP
27 cervical clear cell adenocarcinoma 10.3 NCAM1 SYP
28 dysembryoplastic neuroepithelial tumor 10.3 S100B SYP
29 spermatocele 10.3 NCAM1 SYP
30 anaplastic ependymoma 10.3 S100B SYP
31 angiocentric glioma 10.3 S100B SYP
32 pineocytoma 10.3 S100B SYP
33 cervix small cell carcinoma 10.3 NCAM1 SYP
34 monophasic synovial sarcoma 10.3 RASSF1 S100B
35 papillary ependymoma 10.3 S100B SYP
36 papilloma of choroid plexus 10.3 S100B SYP
37 large cell neuroendocrine carcinoma 10.3 NCAM1 SYP
38 subependymal giant cell astrocytoma 10.3 S100B SYP
39 myxopapillary ependymoma 10.3 NCAM1 S100B
40 mixed ductal-endocrine carcinoma 10.3 NCAM1 SYP
41 adrenal rest tumor 10.3 NCAM1 SYP
42 olfactory neuroblastoma 10.3 S100B SYP
43 cerebral primitive neuroectodermal tumor 10.3 S100B SYP
44 ganglioneuroma 10.3 NCAM1 SYP
45 pancreatic gastrinoma 10.3 S100B SYP
46 ectopic cushing syndrome 10.2 S100B SYP
47 perineurioma 10.2 NCAM1 S100B
48 gangliocytoma 10.2 SYP TH
49 optic nerve glioma 10.2 S100B SYP
50 serine deficiency 10.2 DDC SYP

Graphical network of the top 20 diseases related to Supratentorial Primitive Neuroectodermal Tumor:



Diseases related to Supratentorial Primitive Neuroectodermal Tumor

Symptoms & Phenotypes for Supratentorial Primitive Neuroectodermal Tumor

UMLS symptoms related to Supratentorial Primitive Neuroectodermal Tumor:


fever

Drugs & Therapeutics for Supratentorial Primitive Neuroectodermal Tumor

FDA approved drugs:

# Drug Name Active Ingredient(s) 17 Company Approval Date
1
Afinitor 17 45 EVEROLIMUS Novartis March 2009
2
Sutent 17 45 SUNITINIB MALATE Pfizer May 2011/ January 2006

Drugs for Supratentorial Primitive Neuroectodermal Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 208)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vincristine Approved, Investigational Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
2
Etoposide Approved Phase 2, Phase 3, Phase 1 33419-42-0 36462
3
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
4
Methotrexate Approved Phase 3,Phase 2 1959-05-2, 59-05-2 126941
5
Melphalan Approved Phase 2, Phase 3,Phase 1 148-82-3 460612 4053
6
Carboplatin Approved Phase 2, Phase 3, Phase 1 41575-94-4 10339178 38904 498142
7
Cyclophosphamide Approved, Investigational Phase 2, Phase 3, Phase 1 50-18-0, 6055-19-2 2907
8
Dacarbazine Approved, Investigational Phase 2, Phase 3,Phase 1 4342-03-4 5351166
9
Temozolomide Approved, Investigational Phase 2, Phase 3, Phase 1 85622-93-1 5394
10 Thiotepa Approved, Investigational Phase 2, Phase 3, Phase 1 52-24-4 5453
11
Lenograstim Approved, Investigational Phase 3,Phase 2,Phase 1 135968-09-1
12
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
13
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
14
Topotecan Approved, Investigational Phase 3,Phase 2,Phase 1 119413-54-6, 123948-87-8 60700
15
Donepezil Approved Phase 3,Early Phase 1 120014-06-4 3152
16
Histamine Approved, Investigational Phase 3,Phase 2 51-45-6, 75614-87-8 774
17
Cyproheptadine Approved Phase 3,Phase 2 129-03-3 2913
18
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
19
Ondansetron Approved Phase 3 99614-02-5 4595
20
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
21
Isotretinoin Approved Phase 3,Phase 1 4759-48-2 5282379 5538
22
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
23
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
24
Levoleucovorin Approved, Investigational Phase 3,Phase 2 68538-85-2
25
leucovorin Approved, Nutraceutical Phase 3,Phase 2 58-05-9 143 6006
26
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-30-3 6037
27 Trofosfamide Investigational Phase 2, Phase 3 22089-22-1
28 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
29
Doxil Approved June 1999 Phase 3,Phase 2 31703
30 Alkylating Agents Phase 2, Phase 3, Phase 1
31 Adjuvants, Immunologic Phase 3,Phase 2,Phase 1
32 Folic Acid Antagonists Phase 3,Phase 2
33 Topoisomerase Inhibitors Phase 2, Phase 3, Phase 1
34 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
35 Dermatologic Agents Phase 3,Phase 2,Phase 1
36 Vitamin B Complex Phase 3,Phase 2
37 Etoposide phosphate Phase 2, Phase 3, Phase 1
38 Immunosuppressive Agents Phase 2, Phase 3, Phase 1
39 Antimetabolites Phase 3,Phase 2
40 Antimetabolites, Antineoplastic Phase 3,Phase 2
41 Protective Agents Phase 3,Phase 2,Phase 1
42 Antimitotic Agents Phase 3,Phase 2,Phase 1
43 Antineoplastic Agents, Phytogenic Phase 2, Phase 3, Phase 1
44 Antirheumatic Agents Phase 3,Phase 2,Phase 1
45
Histamine Phosphate Phase 3,Phase 2 51-74-1 65513
46 Dexamethasone acetate Phase 3,Phase 2,Phase 1 1177-87-3
47
Serotonin Phase 3,Phase 2 50-67-9 5202
48 Isophosphamide mustard Phase 3,Phase 2,Phase 1 0
49 Analgesics Phase 3,Phase 2
50 topoisomerase I inhibitors Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 116)

# Name Status NCT ID Phase Drugs
1 Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors Unknown status NCT00179803 Phase 2, Phase 3
2 Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children Unknown status NCT00749723 Phase 2, Phase 3 carboplatin;etoposide;temozolomide;thiotepa, carboplatin, etoposide;temozolomide, thiotepa;etoposide;trofosfamide/etoposide
3 Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors Unknown status NCT00278239 Phase 3
4 Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors Unknown status NCT00392886 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide;methotrexate;temozolomide;thiotepa;vincristine sulfate
5 Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma Completed NCT00336024 Phase 3 etoposide;cyclophosphamide;cisplatin;carboplatin;thiotepa;methotrexate;leucovorin calcium;vincristine sulfate
6 Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor Completed NCT00006461 Phase 3 cisplatin;cyclophosphamide;vincristine sulfate;etoposide
7 Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS Completed NCT00003859 Phase 3 carboplatin;cyclophosphamide;etoposide;vincristine sulfate
8 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
9 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
10 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
11 Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma Recruiting NCT00392327 Phase 3 Vincristine Sulfate;Carboplatin;Cisplatin;Cyclophosphamide;Isotretinoin
12 Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor Active, not recruiting NCT00085202 Phase 3 cisplatin;cyclophosphamide;vincristine
13 Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Active, not recruiting NCT01231906 Phase 3 vincristine sulfate;doxorubicin hydrochloride;cyclophosphamide;ifosfamide;etoposide;topotecan hydrochloride
14 Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer Active, not recruiting NCT01987596 Phase 3
15 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
16 Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors Unknown status NCT00274911 Phase 2 cisplatin;lomustine;vincristine sulfate
17 Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors Unknown status NCT00281905 Phase 2 carboplatin;cisplatin;cyclophosphamide;methotrexate;vincristine sulfate
18 Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor Completed NCT00003211 Phase 2 amifostine trihydrate;cisplatin;cyclophosphamide;vincristine sulfate
19 Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma Completed NCT00006258 Phase 2 cisplatin;cyclophosphamide;etoposide;methotrexate;vincristine sulfate
20 Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor Completed NCT00047177 Phase 2 Oxaliplatin
21 Concurrent Carboplatin and Reduced Dose Craniospinal Radiation for Medulloblastoma and Primitive Neuroectodermal Tumor (PNET) Completed NCT01542736 Phase 2 Carboplatin;Vincristine
22 Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer Completed NCT00002466 Phase 2 cyclophosphamide;doxorubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
23 Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors Completed NCT00025077 Phase 2 carboplatin;cyclophosphamide;thiotepa
24 A Study of Pemetrexed in Children With Recurrent Cancer Completed NCT00520936 Phase 2 pemetrexed
25 A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma Completed NCT00668148 Phase 2
26 Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00006102 Phase 2 becatecarin
27 Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer Completed NCT00003309 Phase 2 cisplatin;cyclophosphamide;etoposide;vincristine sulfate
28 Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors Completed NCT00003203 Phase 2 carboplatin;cisplatin;cyclophosphamide;vincristine sulfate
29 Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma Completed NCT00070525 Phase 2 tipifarnib
30 Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors Completed NCT00005952 Phase 1, Phase 2 temozolomide
31 Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma Completed NCT00008008 Phase 2 cyclophosphamide;thiotepa
32 Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors Completed NCT00003846 Phase 2 carboplatin;cyclophosphamide;thiotepa;vincristine sulfate
33 Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment Completed NCT00066248 Phase 2 cyproheptadine hydrochloride;megestrol acetate
34 Lobradimil and Carboplatin in Treating Children With Brain Tumors Completed NCT00019422 Phase 2 carboplatin;lobradimil
35 Vinorelbine in Treating Children With Recurrent or Refractory Cancers Completed NCT00003234 Phase 2 vinorelbine tartrate
36 Phenylacetate in Treating Children With Recurrent or Progressive Brain Tumors Completed NCT00003241 Phase 2 phenylacetate
37 Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors Completed NCT00002463 Phase 2 MOPP Regimen;Leucovorin Calcium;Mechlorethamine Hydrochloride;Methotrexate;Prednisone;Procarbazine Hydrochloride;Vincristine Sulfate
38 Docetaxel in Treating Children With Recurrent Solid Tumors Completed NCT00002825 Phase 2 docetaxel
39 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
40 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Completed NCT00002752 Phase 1, Phase 2
41 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2 levetiracetam;pregabalin
42 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
43 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
44 Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma Active, not recruiting NCT01977677 Phase 1, Phase 2 temozolomide;plerixafor
45 Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma Active, not recruiting NCT00602667 Phase 2 Induction Chemotherapy;Low-Risk Therapy;High-Risk Therapy;Intermediate-Risk Therapy
46 Crizotinib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma Active, not recruiting NCT00939770 Phase 1, Phase 2 crizotinib
47 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
48 A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720) Terminated NCT00617890 Phase 2
49 Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor Withdrawn NCT00003273 Phase 2 carboplatin;cisplatin;cyclophosphamide;etoposide;leucovorin calcium;methotrexate;temozolomide;thiotepa;vincristine sulfate
50 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1 verteporfin

Search NIH Clinical Center for Supratentorial Primitive Neuroectodermal Tumor

Genetic Tests for Supratentorial Primitive Neuroectodermal Tumor

Anatomical Context for Supratentorial Primitive Neuroectodermal Tumor

MalaCards organs/tissues related to Supratentorial Primitive Neuroectodermal Tumor:

38
Brain, Bone, Endothelial, Bone Marrow, Spinal Cord, T Cells, Pineal

Publications for Supratentorial Primitive Neuroectodermal Tumor

Articles related to Supratentorial Primitive Neuroectodermal Tumor:

(show all 50)
# Title Authors Year
1
Outcome for children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor (CNS-PNET) - a retrospective analysis spanning 40 years of treatment. ( 28325133 )
2017
2
Radiation-Induced Supratentorial Primitive Neuroectodermal Tumor after Treatment for Non-Hodgkin's Lymphoma. ( 26242031 )
2015
3
Treatment outcome and patterns of failure in patients of non-pineal supratentorial primitive neuroectodermal tumor: review of literature and clinical experience form a regional cancer center in north India. ( 25990846 )
2015
4
MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system . ( 24470553 )
2014
5
A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children. ( 24470556 )
2014
6
Supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhage in adult. ( 24966562 )
2014
7
A supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhage in a 42-year-old man: a case report and review of the literature. ( 23537064 )
2013
8
Proton radiation therapy for pediatric medulloblastoma and supratentorial primitive neuroectodermal tumors: outcomes for very young children treated with upfront chemotherapy. ( 23790826 )
2013
9
Supratentorial primitive neuroectodermal tumor in an adult: a case report and review of the literature. ( 23095172 )
2012
10
Severe allergic reactions to thiol-based cytoprotective agents mesna and amifostine in a child with a supratentorial primitive neuroectodermal tumor. ( 21646919 )
2011
11
Supratentorial primitive neuroectodermal tumors of the central nervous system in adults: molecular and histopathologic analysis of 12 cases. ( 21378543 )
2011
12
Supratentorial primitive neuroectodermal tumor (PNET): an uncommon location. ( 22297899 )
2011
13
Treatment of a supratentorial primitive neuroectodermal tumor using magnetic resonance-guided laser-induced thermal therapy. ( 22044371 )
2011
14
Late complete remission of supratentorial primitive neuroectodermal tumor (CNS-PNET) after multiple relapses. ( 21113945 )
2011
15
Reduced-dose craniospinal radiotherapy followed by high-dose chemotherapy and autologous stem cell rescue for children with newly diagnosed high-risk medulloblastoma or supratentorial primitive neuroectodermal tumor. ( 21120191 )
2010
16
Supratentorial primitive neuroectodermal tumor metastasis to the abdomen via a ventriculoperitoneal shunt. ( 20526591 )
2010
17
Successful radiation therapy for supratentorial primitive neuroectodermal tumor and epidermolysis bullosa simplex. ( 19760773 )
2010
18
Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas. ( 20515335 )
2010
19
Therapeutic Difficulty in a Case of Supratentorial Primitive Neuroectodermal Tumor Diagnosed during Pregnancy. ( 19242570 )
2009
20
Frequent IDH1 mutations in supratentorial primitive neuroectodermal tumors (sPNET) of adults but not children. ( 19411854 )
2009
21
Secondary supratentorial primitive neuroectodermal tumor following treatment of childhood osteosarcoma. ( 19434734 )
2009
22
Lipomatous supratentorial primitive neuroectodermal tumor with glioblastomatous differentiation. ( 19118780 )
2009
23
A supratentorial primitive neuroectodermal tumor in an adult: a case report and review of the literature. ( 17713720 )
2008
24
High-dose chemotherapy and autologous stem cell rescue in children with newly diagnosed high-risk or relapsed medulloblastoma or supratentorial primitive neuroectodermal tumor. ( 17066462 )
2007
25
Supratentorial primitive neuroectodermal tumor during pregnancy. Case report. ( 17505462 )
2007
26
[Different hypermethylation status of RASSF1A in medulloblastoma and supratentorial primitive neuroectodermal tumor]. ( 17374234 )
2007
27
Supratentorial primitive neuroectodermal tumor (sPNET). ( 16612986 )
2006
28
Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells. ( 17016591 )
2006
29
High-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors. ( 16783165 )
2006
30
Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials. ( 16575007 )
2006
31
Long-term relapse-free survival with supratentorial primitive neuroectodermal tumor in an adult: a case report. ( 16528456 )
2006
32
Molecular genetics of supratentorial primitive neuroectodermal tumors and pineoblastoma. ( 16398467 )
2005
33
High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors. ( 15719272 )
2005
34
Secondary supratentorial primitive neuroectodermal tumor following irradiation in a patient with low-grade astrocytoma. ( 15661719 )
2005
35
Supratentorial primitive neuroectodermal tumor in an aged patient--case report--. ( 16247240 )
2005
36
Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor. ( 15712180 )
2005
37
[Supratentorial primitive neuroectodermal tumor: report of a surgical case]. ( 15352632 )
2004
38
Somatostatin receptor subtype 2 is expressed by supratentorial primitive neuroectodermal tumors of childhood and can be targeted for somatostatin receptor imaging. ( 15131035 )
2004
39
Patterns of failure in relation to radiotherapy fields in supratentorial primitive neuroectodermal tumor. ( 15001261 )
2004
40
Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor. ( 15310781 )
2004
41
Valproic acid induces differentiation of a supratentorial primitive neuroectodermal tumor. ( 15739631 )
2004
42
PTEN and DMBT1 homozygous deletion and expression in medulloblastomas and supratentorial primitive neuroectodermal tumors. ( 15547761 )
2004
43
A novel case of a CAT to AAT transversion in codon 179 of the p53 gene in a supratentorial primitive neuroectodermal tumor harbored by a young girl. Case report and review of the literature. ( 12837982 )
2003
44
Unusual aberration involving the short arm of chromosome 11 in an 8-month-old patient with a supratentorial primitive neuroectodermal tumor. ( 12606132 )
2003
45
Mediastinal T-cell lymphoma in a boy 7 years after treatment of supratentorial primitive neuroectodermal tumor. ( 12902924 )
2003
46
Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: results of a collaborative study. ( 11352962 )
2001
47
Cytogenetic and histopathologic studies of congenital supratentorial primitive neuroectodermal tumors: a case report. ( 11349224 )
2001
48
Supratentorial primitive neuroectodermal tumor in children: clinical features, treatment outcome and prognostic factors. ( 10447606 )
1999
49
A continuous cell line (KK-2) from a supratentorial primitive neuroectodermal tumor. ( 1323907 )
1992
50
Immunophenotype profile of childhood medulloblastomas and supratentorial primitive neuroectodermal tumors using 16 monoclonal antibodies. ( 2196109 )
1990

Variations for Supratentorial Primitive Neuroectodermal Tumor

Expression for Supratentorial Primitive Neuroectodermal Tumor

Search GEO for disease gene expression data for Supratentorial Primitive Neuroectodermal Tumor.

Pathways for Supratentorial Primitive Neuroectodermal Tumor

GO Terms for Supratentorial Primitive Neuroectodermal Tumor

Cellular components related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 9.33 DDC S100B TH
2 terminal bouton GO:0043195 8.96 SYP TH
3 synaptic vesicle GO:0008021 8.8 DDC SYP TH

Biological processes related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 memory GO:0007613 9.51 S100B TH
2 cellular response to drug GO:0035690 9.49 DDC TH
3 cellular response to growth factor stimulus GO:0071363 9.48 DDC TH
4 regulation of neuronal synaptic plasticity GO:0048168 9.46 S100B SYP
5 multicellular organism aging GO:0010259 9.43 DDC TH
6 cellular response to alkaloid GO:0071312 9.4 DDC TH
7 dopamine biosynthetic process GO:0042416 9.37 DDC TH
8 catecholamine biosynthetic process GO:0042423 9.32 DDC TH
9 aminergic neurotransmitter loading into synaptic vesicle GO:0015842 9.26 DDC TH
10 response to pyrethroid GO:0046684 9.16 DDC TH
11 isoquinoline alkaloid metabolic process GO:0033076 8.96 DDC TH
12 phytoalexin metabolic process GO:0052314 8.62 DDC TH

Molecular functions related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 amino acid binding GO:0016597 8.62 DDC TH

Sources for Supratentorial Primitive Neuroectodermal Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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