MCID: SPR008
MIFTS: 34

Supratentorial Primitive Neuroectodermal Tumor malady

Rare diseases, Neuronal diseases, Cancer diseases categories

Aliases & Classifications for Supratentorial Primitive Neuroectodermal Tumor

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Aliases & Descriptions for Supratentorial Primitive Neuroectodermal Tumor:

Name: Supratentorial Primitive Neuroectodermal Tumor 8 42 10 61
Ewings Sarcoma-Primitive Neuroectodermal Tumor 61
Peripheral Neuroectodermal Tumor 42
 
Primative Neuroectodermal Tumor 42
Supratentorial Pnet 8
Pnet 42


Classifications:



External Ids:

Disease Ontology8 DOID:4791
SNOMED-CT56 39781001
NCIt39 C6968

Summaries for Supratentorial Primitive Neuroectodermal Tumor

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MalaCards based summary: Supratentorial Primitive Neuroectodermal Tumor, also known as ewings sarcoma-primitive neuroectodermal tumor, is related to medulloblastoma and merkel cell carcinoma. An important gene associated with Supratentorial Primitive Neuroectodermal Tumor is SLITRK6 (SLIT and NTRK-like family, member 6), and among its related pathways are SIDS Susceptibility Pathways and Neuroscience. The compounds 111in-pentetreotide and amine have been mentioned in the context of this disorder. Affiliated tissues include t cells, and related mouse phenotypes are nervous system and behavior/neurological.

Related Diseases for Supratentorial Primitive Neuroectodermal Tumor

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Diseases related to Supratentorial Primitive Neuroectodermal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 84)
idRelated DiseaseScoreTop Affiliating Genes
1medulloblastoma31.1SSTR2, SYP, S100B
2merkel cell carcinoma30.9SYP
3neuroblastoma30.8SYP
4neuroendocrine tumor30.7SSTR2
5pilocytic astrocytoma30.4SYP, S100B
6olfactory neuroblastoma30.0S100B, SYP
7neuroectodermal tumor11.2
8supratentorial primitive neuroectodermal tumors, childhood10.6
9sarcoma10.6
10malignant peripheral neuroectodermal tumor of the cervix uteri10.5
11malignant peripheral neuroectodermal tumor of the corpus uteri10.4
12atypical teratoid rhabdoid tumor10.4
13epidermolysis bullosa simplex10.4
14childhood medulloblastoma10.4
15astrocytoma10.4
16epidermolysis bullosa10.4
17mediastinitis10.4
18pineoblastoma10.4
19pineoblastoma, childhood10.4
20subependymal giant cell astrocytoma10.4SYP
21dysembryoplastic neuroepithelial tumor10.4SYP
22glomus tumor10.4SYP
23peripheral primitive neuroectodermal tumor10.4
24pancreatitis10.3
25amyotrophic lateral sclerosis 110.2SYP
26rhabdoid tumor10.2
27ewing sarcoma10.2
28soft tissue peripheral neuroepithelioma10.2
29extraosseous ewing's sarcoma10.2
30prostatitis10.2
31vaginitis10.2
32teratocarcinoma10.1SYP, ASCL1
33medullary thyroid carcinoma, familial10.1ASCL1, SSTR2
34gastrinoma10.1SYP, SSTR2
35cerebral primitive neuroectodermal tumor10.1
36neuronitis10.1
37cerebritis10.1
38glioblastoma10.1
39multiple endocrine neoplasia10.1
40papillary ependymoma10.1S100B, SYP
41choroid plexus papilloma10.1SYP, S100B
42papillary carcinoma10.0SYP, SSTR2
43pineocytoma10.0S100B, SYP
44granular cell tumor10.0SYP, S100B
45ganglioneuroblastoma10.0SYP, S100B
46hemangioblastoma10.0SYP, S100B
47pancreatic cancer10.0SYP, SSTR2
48ganglioglioma10.0S100B, SYP
49ganglioneuroma10.0SYP, S100B
50neurofibroma10.0S100B, SYP

Graphical network of the top 20 diseases related to Supratentorial Primitive Neuroectodermal Tumor:



Diseases related to supratentorial primitive neuroectodermal tumor

Symptoms for Supratentorial Primitive Neuroectodermal Tumor

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Drugs & Therapeutics for Supratentorial Primitive Neuroectodermal Tumor

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Drug clinical trials:

Search ClinicalTrials for Supratentorial Primitive Neuroectodermal Tumor

Search NIH Clinical Center for Supratentorial Primitive Neuroectodermal Tumor

Genetic Tests for Supratentorial Primitive Neuroectodermal Tumor

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Anatomical Context for Supratentorial Primitive Neuroectodermal Tumor

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MalaCards organs/tissues related to Supratentorial Primitive Neuroectodermal Tumor:

31
T cells

Animal Models for Supratentorial Primitive Neuroectodermal Tumor or affiliated genes

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MGI Mouse Phenotypes related to Supratentorial Primitive Neuroectodermal Tumor:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.9ASCL1, SSTR2, SYP, SLITRK6, DDC
2MP:00053867.3SLITRK6, S100B, SSTR2, ASCL1, DDC

Publications for Supratentorial Primitive Neuroectodermal Tumor

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Articles related to Supratentorial Primitive Neuroectodermal Tumor:

(show all 45)
idTitleAuthorsYear
1
Supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhage in adult. (24966562)
2014
2
A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children. (24470556)
2014
3
A supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhage in a 42-year-old man: a case report and review of the literature. (23537064)
2013
4
Proton radiation therapy for pediatric medulloblastoma and supratentorial primitive neuroectodermal tumors: outcomes for very young children treated with upfront chemotherapy. (23790826)
2013
5
Supratentorial primitive neuroectodermal tumor in an adult: a case report and review of the literature. (23095172)
2012
6
Severe allergic reactions to thiol-based cytoprotective agents mesna and amifostine in a child with a supratentorial primitive neuroectodermal tumor. (21646919)
2011
7
Treatment of a supratentorial primitive neuroectodermal tumor using magnetic resonance-guided laser-induced thermal therapy. (22044371)
2011
8
Late complete remission of supratentorial primitive neuroectodermal tumor (CNS-PNET) after multiple relapses. (21113945)
2011
9
Supratentorial primitive neuroectodermal tumors of the central nervous system in adults: molecular and histopathologic analysis of 12 cases. (21378543)
2011
10
Supratentorial primitive neuroectodermal tumor (PNET): an uncommon location. (22297899)
2011
11
Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas. (20515335)
2010
12
Supratentorial primitive neuroectodermal tumor metastasis to the abdomen via a ventriculoperitoneal shunt. (20526591)
2010
13
Reduced-dose craniospinal radiotherapy followed by high-dose chemotherapy and autologous stem cell rescue for children with newly diagnosed high-risk medulloblastoma or supratentorial primitive neuroectodermal tumor. (21120191)
2010
14
Successful radiation therapy for supratentorial primitive neuroectodermal tumor and epidermolysis bullosa simplex. (19760773)
2010
15
Lipomatous supratentorial primitive neuroectodermal tumor with glioblastomatous differentiation. (19118780)
2009
16
Frequent IDH1 mutations in supratentorial primitive neuroectodermal tumors (sPNET) of adults but not children. (19411854)
2009
17
Secondary supratentorial primitive neuroectodermal tumor following treatment of childhood osteosarcoma. (19434734)
2009
18
Therapeutic Difficulty in a Case of Supratentorial Primitive Neuroectodermal Tumor Diagnosed during Pregnancy. (19242570)
2009
19
A supratentorial primitive neuroectodermal tumor in an adult: a case report and review of the literature. (17713720)
2008
20
Different hypermethylation status of RASSF1A in medulloblastoma and supratentorial primitive neuroectodermal tumor]. (17374234)
2007
21
High-dose chemotherapy and autologous stem cell rescue in children with newly diagnosed high-risk or relapsed medulloblastoma or supratentorial primitive neuroectodermal tumor. (17066462)
2007
22
Supratentorial primitive neuroectodermal tumor during pregnancy. Case report. (17505462)
2007
23
High-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors. (16783165)
2006
24
Supratentorial primitive neuroectodermal tumor (sPNET). (16612986)
2006
25
Long-term relapse-free survival with supratentorial primitive neuroectodermal tumor in an adult: a case report. (16528456)
2006
26
Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials. (16575007)
2006
27
Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells. (17016591)
2006
28
Molecular genetics of supratentorial primitive neuroectodermal tumors and pineoblastoma. (16398467)
2005
29
Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor. (15712180)
2005
30
High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors. (15719272)
2005
31
Supratentorial primitive neuroectodermal tumor in an aged patient--case report--. (16247240)
2005
32
Secondary supratentorial primitive neuroectodermal tumor following irradiation in a patient with low-grade astrocytoma. (15661719)
2005
33
Somatostatin receptor subtype 2 is expressed by supratentorial primitive neuroectodermal tumors of childhood and can be targeted for somatostatin receptor imaging. (15131035)
2004
34
Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor. (15310781)
2004
35
Patterns of failure in relation to radiotherapy fields in supratentorial primitive neuroectodermal tumor. (15001261)
2004
36
Supratentorial primitive neuroectodermal tumor: report of a surgical case]. (15352632)
2004
37
Valproic acid induces differentiation of a supratentorial primitive neuroectodermal tumor. (15739631)
2004
38
PTEN and DMBT1 homozygous deletion and expression in medulloblastomas and supratentorial primitive neuroectodermal tumors. (15547761)
2004
39
Unusual aberration involving the short arm of chromosome 11 in an 8-month-old patient with a supratentorial primitive neuroectodermal tumor. (12606132)
2003
40
Mediastinal T-cell lymphoma in a boy 7 years after treatment of supratentorial primitive neuroectodermal tumor. (12902924)
2003
41
A novel case of a CAT to AAT transversion in codon 179 of the p53 gene in a supratentorial primitive neuroectodermal tumor harbored by a young girl. Case report and review of the literature. (12837982)
2003
42
Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: results of a collaborative study. (11352962)
2001
43
Supratentorial primitive neuroectodermal tumor in children: clinical features, treatment outcome and prognostic factors. (10447606)
1999
44
A continuous cell line (KK-2) from a supratentorial primitive neuroectodermal tumor. (1323907)
1992
45
Immunophenotype profile of childhood medulloblastomas and supratentorial primitive neuroectodermal tumors using 16 monoclonal antibodies. (2196109)
1990

Variations for Supratentorial Primitive Neuroectodermal Tumor

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Expression for genes affiliated with Supratentorial Primitive Neuroectodermal Tumor

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Search GEO for disease gene expression data for Supratentorial Primitive Neuroectodermal Tumor.

Pathways for genes affiliated with Supratentorial Primitive Neuroectodermal Tumor

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Pathways related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
18.9SSTR2, ASCL1, DDC
28.6S100B, SYP, DDC

Compounds for genes affiliated with Supratentorial Primitive Neuroectodermal Tumor

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Compounds related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

(show all 32)
idCompoundScoreTop Affiliating Genes
1111in-pentetreotide449.7SYP, SSTR2
2amine449.7SYP, DDC
3spec-t449.6DDC, SSTR2
45-hydroxytryptamine449.6DDC, SYP
5s 100449.5SYP, S100B
6reticulin449.5S100B, SYP
7mucicarmine449.5S100B, SYP
8b 723449.5SYP, S100B
9hematoxylin449.4SYP, S100B
10dbc-amp449.4S100B, SYP
11agarose449.2DDC, S100B
12formaldehyde44 2410.2S100B, SYP
13histamine44 28 2411.1SSTR2, DDC, SYP
14l-amino acid449.0S100B, DDC, SYP
15catecholamine449.0DDC, S100B, SYP
16choline44 24 1111.0S100B, DDC, SYP
17gaba449.0S100B, SYP, DDC
18histidine449.0DDC, S100B, SYP
19norepinephrine44 24 1110.9S100B, SYP, DDC
20gtp44 289.9SYP, DDC, S100B
21acth448.9S100B, SYP, SSTR2
22ionomycin448.8S100B, SYP
23paraffin448.8SSTR2, SYP, S100B
24forskolin44 50 1110.8SSTR2, S100B, SYP
25glutamate448.8S100B, SYP, DDC
26progesterone44 28 60 24 1112.8SSTR2, S100B, SYP
27vegf448.7SSTR2, SYP, S100B
28retinoic acid44 249.6ASCL1, S100B, SYP
29estrogen448.5S100B, SSTR2, SYP
30glucose448.5SSTR2, S100B, DDC
31dopamine44 28 24 1110.9ASCL1, S100B, SYP, SSTR2, DDC
32tyrosine447.9DDC, ASCL1, SYP, SSTR2, S100B

GO Terms for genes affiliated with Supratentorial Primitive Neuroectodermal Tumor

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Cellular components related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1neuronal cell bodyGO:00430258.7S100B, ASCL1, DDC

Biological processes related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1axonogenesisGO:00074099.2SLITRK6, S100B
2regulation of neuronal synaptic plasticityGO:00481688.8S100B, SYP

Sources for Supratentorial Primitive Neuroectodermal Tumor

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet