Susac Syndrome disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Susac Syndrome

Sources:
⁴²NIH Rare Diseases, ³²MalaCards
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NIH Rare Diseases:⁴² Susac syndrome is an autoimmune condition that affects very fine blood vessels in the brain, retina, and cochlea (inner ear). it is characterized by three main symptoms: encephalopathy (which can cause headache, mild memory loss, personality changes, and confusion); sensorineural hearing loss; and vision loss. most people do not have all the symptoms of susac syndrome at the beginning of their illness but develop symptoms over the course of several years. susac syndrome affects women more than men and the age of onset is usually between 20 and 40 years. the cause of this condition is still unknown. corticosteroids, antiplatelets, anticoagulation, and cyclophosphamide have been used to treat susac syndrome. however, the extent to which individuals respond to treatment is not clear. improvement may occur spontaneously although in some cases there may be residual dysfunction. last updated: 7/21/2014

MalaCards based summary: Susac Syndrome, also known as retinocochleocerebral vasculopathy, is related to retinitis and retinal artery occlusion. Affiliated tissues include brain, retina and eye.

Aliases & Classifications for Susac Syndrome

Sources:
⁴²NIH Rare Diseases, ⁴⁸Orphanet, ⁶¹UMLS, ³⁵MESH via Orphanet, ²⁷ICD10 via Orphanet, ⁶²UMLS via Orphanet
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Susac Syndrome, Aliases & Descriptions:

Name: Susac Syndrome ⁴² ⁴⁸ ⁶¹

Retinocochleocerebral Vasculopathy ⁴² ⁴⁸ ⁶¹

Retinopathy-Encephalopathy-Deafness Associated with Microangiopathy ⁴⁸

Small Infarctions of Cochlear, Retinal and Encephalic Tissue ⁴⁸

Sicret Syndrome ⁴²

Sicret Syndrome ⁴⁸

Red-M ⁴⁸

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases, Ear diseases, Cardiovascular diseases

ICD10: ²⁷

Diseases of the circulatory system

Cerebrovascular diseases

Other cerebrovascular diseases

Cerebral arteritis, not elsewhere classified

Orphanet: ⁴⁸

Rare neurological diseases

Characteristics (Orphanet epidemiological data):

⁴⁸

retinocochleocerebral vasculopathy:
Age of onset: Variable; Age of death: Normal

External Ids:

MESH via Orphanet³⁵ D055955

ICD10 via Orphanet²⁷ I67.7

UMLS via Orphanet⁶² C2717757

Related Diseases for Susac Syndrome

Sources:
¹⁸GeneCards, ¹⁹GeneDecks
See all sources

Diseases related to Susac Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 16)

id	Related Disease	Score
1	retinitis	10.6
2	retinal artery occlusion	10.5
3	central retinal artery occlusion	10.4
4	multiple sclerosis	10.2
5	branch retinal artery occlusion	10.2
6	bipolar disorder	10.1
7	hepatitis	10.1
8	multifocal motor neuropathy	10.1
9	hepatitis c	10.1
10	sensorineural hearing loss	10.1
11	cauda equina syndrome	10.1
12	retinal vasculitis	10.1
13	cervicitis	10.1
14	neuropathy	10.1
15	vasculitis	10.1
16	endotheliitis	10.1

Graphical network of diseases related to Susac Syndrome:

Symptoms for Susac Syndrome

Drugs & Therapeutics for Susac Syndrome

Sources:
⁴¹NIH Clinical Center, ⁶ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Susac Syndrome

Search NIH Clinical Center for Susac Syndrome

Genetic Tests for Susac Syndrome

Anatomical Context for Susac Syndrome

Sources:
³²MalaCards
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MalaCards organs/tissues related to Susac Syndrome:

³²

Brain, Retina, Eye, Spinal cord, Endothelial

Animal Models for Susac Syndrome or affiliated genes

Publications for Susac Syndrome

Sources:
⁵¹PubMed
See all sources

Articles related to Susac Syndrome:

(show top 50) (show all 76)

id	Title	Authors	Year
1	Update on Susac syndrome: new insights in brain and retinal imaging and treatment options. (24662104)	DAPrr J.... Kleffner I.	2014
2	Susac syndrome: diverse clinical findings and treatment. (25295909)	Bardal R.C.... Maia M.	2014
3	Recurrence of Susac Syndrome following 23 Years of Remission. (24987361)	Feresiadou A.... Melberg A.	2014
4	Clinical, paraclinical and serological findings in Susac syndrome: an international multicenter study. (24606999)	Jarius S.... Wildemann B.	2014
5	Susac syndrome. (25337735)	Freua F.... Rabello G.D.	2014
6	Unilateral central retinal artery occlusion as the sole presenting sign of Susac syndrome in a young man: case report. (24232952)	Egan R.A.	2013
7	Susac syndrome: an Italian case. (23828373)	Ferrante E.... Protti A.	2013
8	Characteristics of Susac syndrome: a review of all reported cases. (23628737)	DAPrr J.... Kleffner I.	2013
9	Susac Syndrome Treated with Subcutaneous Immunoglobulin. (24335148)	Kleffner I.... Schilling M.	2013
10	A case of Susac syndrome. (24082778)	Cho H.J.... Kim J.W.	2013
11	Progression of retinal artery occlusion from one eye to the other seems to be a characteristic finding in Susac syndrome. (24510092)	Yildirim Y.... Kaya A.	2013
12	Unilateral central retinal artery occlusion as the sole presenting sign of Susac syndrome in a young man: case report. (23929083)	dos ApA^stolos-Pereira S.L.... Monteiro M.L.	2013
13	A case of Susac syndrome with cervical spinal cord involvement on MRI. (24365248)	Hua L.H.... Okuda D.T.	2013
14	Susac syndrome in a patient with human immunodeficiency virus infection. (23690260)	Longbrake E.E.... Clifford D.B.	2013
15	Reply: Progression of retinal artery occlusion in Susac syndrome. (24510093)	Monteiro M.L.	2013
16	Reply: Fibrin-like material in the retinal arterioles and fluorescein angiography findings in Susac syndrome. (24232953)	Monteiro M.L.	2013
17	Susac syndrome. A differential diagnosis for demyelination. (23291802)	Vattoth S.... Vaphiades M.S.	2013
18	Susac syndrome: clinical characteristics and treatment in 29 new cases. (22221557)	Mateen F.J.... Petty G.W.	2012
19	A brief review of Susac syndrome. (22640902)	Kleffner I.... Ringelstein E.B.	2012
20	Exacerbation of Susac syndrome retinopathy by interferon Beta-1a. (22801853)	Laird P.W.... Yeh S.	2012
21	Susac syndrome and pregnancy: disease management. (21325959)	Deane K.D.... Striebich C.C.	2011
22	Recurrent bilateral branch retinal artery occlusion with hearing loss and encephalopathy: the first case report of Susac syndrome in Korea. (22065912)	Joe S.G.... Yoon Y.H.	2011
23	Review of Susac syndrome. (21897238)	Bitra R.K.... Eggenberger E.	2011
24	Susac syndrome: outcome of unilateral cochlear implantation. (21481296)	Grover N.... Ramsden J.D.	2011
25	Gass plaques and fluorescein leakage in Susac Syndrome. (20880549)	Egan R.A.... Susac J.O.	2010
26	CT and MR imaging of Susac syndrome in a young male presenting with acute disorientation. (20189079)	Allmendinger A.M.... Destian S.	2010
27	Susac syndrome. (20686320)	LA^pez Ruiz D.J.... Bravo Rodriguez F.d.e. .A.	2010
28	Severe retention hyperkeratosis occurring with Susac syndrome. (21062602)	Harris K.... Bowen A.R.	2010
29	Susac syndrome as an example of a rare vasculopathy. (19341183)	Olszanecka-Glinianowicz M.... Hrycek A.	2009
30	Case 142: Susac syndrome. (19188329)	Demir M.K.	2009
31	Is Susac syndrome (microangiopathy of the inner ear, retina, and central nervous system) an underdiagnosed cause of sensorineural hearing loss? (18633920)	Westreich R.... Chandrasekhar S.	2008
32	Diffusion tensor imaging demonstrates fiber impairment in Susac syndrome. (17959768)	Kleffner I.... Ringelstein E.B.	2008
33	Susac syndrome and vestibular-evoked myogenic potentials. (18359373)	Magliulo G.... Stasolla A.	2008
34	Susac syndrome in a patient with hepatitis C. (17414876)	Chawla A.... Doran M.	2007
35	Long-term outcome in Susac syndrome. (17435589)	Aubart-Cohen F.... Papo T.	2007
36	Re: Susac syndrome in four male patients. (18040266)	Lubow M.	2007
37	Susac syndrome in a young child. (17476496)	Eluvathingal Muttikkal T.J.... Keluth Chavan V.N.	2007
38	Susac syndrome in four male patients. (17151493)	Snyers B.... Sindic C.	2006
39	Susac syndrome with frontal intermittent rhythmic delta activity (FIRDA). (17168166)	Woolridge D.... Hoppe B.	2006
40	Susac syndrome: retinocochleocerebral vasculopathy. (15185430)	SzilasiovA! J.... KlA-movA! E.	2004
41	Susac syndrome: serial diffusion-weighted MR imaging. (15607101)	Xu M.S.... Lim C.C.	2004
42	Evolution of lesions in Susac syndrome at serial MR imaging with diffusion-weighted imaging and apparent diffusion coefficient values. (15140708)	White M.L.... Smoker W.R.	2004
43	Susac syndrome. (12439681)	Sandhya V.... Anand N.	2002
44	Susac syndrome and multiple sclerosis. (11296064)	Sirikci A.	2001
45	Susac syndrome: a vasospastic disorder? (11456021)	Flammer J.... Haufschild T.	2001
46	A case of Susac syndrome. (11057732)	Yellin M.W.... Johnson T.W.	2000
47	Susac syndrome. (10844072)	Murata Y.... Negi A.	2000
48	Microangiopathy of the inner ear, retina, and brain (Susac syndrome): report of a case. (10628717)	Ayache D.... Gout O.	2000
49	Susac syndrome: microangiopathy of the retina, cochlea and brain. (11097286)	Saw V.P.... Watson J.D.	2000
50	Microangiopathy of the brain, retina, and cochlea (Susac syndrome). A report of five cases and a review of the literature. (9627654)	O'Halloran H.S.... Berger J.R.	1998