Susac Syndrome disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Aliases & Classifications for Susac Syndrome

Sources:
⁴⁵NIH Rare Diseases, ⁵¹Orphanet, ⁶⁵UMLS, ³⁷MESH via Orphanet, ⁶⁶UMLS via Orphanet, ²⁸ICD10 via Orphanet
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Aliases & Descriptions for Susac Syndrome:

Name: Susac Syndrome ⁴⁵ ⁵¹ ⁶⁵

Retinocochleocerebral Vasculopathy ⁴⁵ ⁵¹

Retinopathy-Encephalopathy-Deafness Associated with Microangiopathy ⁵¹

Small Infarctions of Cochlear, Retinal and Encephalic Tissue ⁵¹

Sicret Syndrome ⁴⁵

Sicret Syndrome ⁵¹

Red-M ⁵¹

Characteristics:

Orphanet epidemiological data:

⁵¹

susac syndrome:
Age of onset: All ages; Age of death: normal life expectancy

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Neuronal diseases, Ear diseases, Cardiovascular diseases

See all MalaCards categories (disease lists)

ICD10: ²⁸

Diseases of the circulatory system

Cerebrovascular diseases

Other cerebrovascular diseases

Cerebral arteritis, not elsewhere classified

Orphanet: ⁵¹

Rare neurological diseases

External Ids:

Orphanet⁵¹ 838

MESH via Orphanet³⁷ D055955

UMLS via Orphanet⁶⁶ C2717757

ICD10 via Orphanet²⁸ I67.7

UMLS⁶⁵ C2717757

Summaries for Susac Syndrome

Sources:
⁴⁵NIH Rare Diseases, ³³MalaCards
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NIH Rare Diseases:⁴⁵ Susac syndrome is an autoimmune condition that affects very fine blood vessels in the brain, retina, and cochlea (inner ear). it is characterized by three main symptoms: encephalopathy (which can cause headache, mild memory loss, personality changes, and confusion); sensorineural hearing loss; and vision loss. most people do not have all the symptoms of susac syndrome at the beginning of their illness but develop symptoms over the course of several years. susac syndrome affects women more than men and the age of onset is usually between 20 and 40 years. the cause of this condition is still unknown. corticosteroids, antiplatelets, anticoagulation, and cyclophosphamide have been used to treat susac syndrome. however, the extent to which individuals respond to treatment is not clear. improvement may occur spontaneously although in some cases there may be residual dysfunction. last updated: 7/21/2014

MalaCards based summary: Susac Syndrome, also known as retinocochleocerebral vasculopathy, is related to retinitis and retinal artery occlusion, and has symptoms including neuromuscular manifestations, neurobehavioral manifestations and vasculitic rash. Affiliated tissues include retina, brain and eye.

Related Diseases for Susac Syndrome

Sources:
²⁰GeneCards, ¹⁹GeneAnalytics
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Diseases related to Susac Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)

id	Related Disease	Score
1	retinitis	10.4
2	retinal artery occlusion	10.3
3	central retinal artery occlusion	10.1
4	branch retinal artery occlusion	10.0
5	encephalopathy	10.0
6	bipolar disorder	9.8
7	hepatitis	9.8
8	multifocal motor neuropathy	9.8
9	sensorineural hearing loss	9.8
10	retinal vasculitis	9.8
11	cauda equina syndrome	9.8
12	hepatitis c	9.8
13	cervicitis	9.8
14	vasculitis	9.8
15	neuropathy	9.8
16	central serous chorioretinopathy	9.8
17	endotheliitis	9.8

Graphical network of diseases related to Susac Syndrome:

Symptoms for Susac Syndrome

Sources:
⁶⁵UMLS
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UMLS symptoms related to Susac Syndrome:

neuromuscular manifestations, neurobehavioral manifestations, vasculitic rash, cupulolithiasis, eye pain, photophobia, vertigo, seizures, reflex, abnormal, paresis, pain, meningism, eye manifestations, earache

Drugs & Therapeutics for Susac Syndrome

Sources:
⁴⁴NIH Clinical Center, ⁴ClinicalTrials
See all MalaCards sources

Interventional clinical trials:

id	Name	Status	NCT ID
1	Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome	Recruiting	NCT01481662
2	Investigation of Biomarkers in Susac Syndrome	Recruiting	NCT01273792
3	Establishment of Biomarkers for Fabry Disease	Recruiting	NCT01165697

Search NIH Clinical Center for Susac Syndrome

Genetic Tests for Susac Syndrome

Anatomical Context for Susac Syndrome

Sources:
³³MalaCards
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MalaCards organs/tissues related to Susac Syndrome:

³³

Retina, Brain, Eye, Cortex, Lung, Endothelial, Prostate

Animal Models for Susac Syndrome or affiliated genes

Publications for Susac Syndrome

Sources:
⁵⁴PubMed
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Articles related to Susac Syndrome:

(show top 50) (show all 97)

id	Title	Authors	Year
1	Teen with Encephalopathy: Early Recognition of and Intervention for Susac Syndrome. (26991403)	Bullock D.R.... Hobday P.M.	2016
2	Potential benefits of early aggressive immunotherapy in Susac syndrome. (26786477)	London F.... Sindic C.J.	2016
3	Treatment of Susac Syndrome. (26715396)	Vodopivec I.... Prasad S.	2016
4	Do not forget susac syndrome in patients with unexplained acute confusion. (25680663)	Star M.... Biller J.	2015
5	SUSAC SYNDROME. (26352322)	Patel K.H.... McDonald H.R.	2015
6	Retinal pathology in Susac syndrome detected by spectral-domain optical coherence tomography. (26203089)	Ringelstein M.... DAPrr J.	2015
7	A case of susac syndrome. (25553231)	Zande J.L.... Farooq M.U.	2015
8	Central Serous Chorioretinopathy in Susac Syndrome. (25786202)	Artunay O.... Ertugay C.K.	2015
9	Update on Susac syndrome: new insights in brain and retinal imaging and treatment options. (24662104)	DAPrr J.... Kleffner I.	2014
10	Susac syndrome: diverse clinical findings and treatment. (25295909)	Bardal R.C.... Maia M.	2014
11	Recurrence of Susac Syndrome following 23 Years of Remission. (24987361)	Feresiadou A.... Melberg A.	2014
12	What is Susac syndrome? - A brief review of articles. (25632332)	Nazari F.... Abdi S.	2014
13	Unilateral central retinal artery occlusion as the sole presenting sign of Susac syndrome in a young man: case report. (24232952)	Egan R.A.	2013
14	Susac syndrome: an Italian case. (23828373)	Ferrante E.... Protti A.	2013
15	Characteristics of Susac syndrome: a review of all reported cases. (23628737)	DAPrr J.... Kleffner I.	2013
16	Susac Syndrome Treated with Subcutaneous Immunoglobulin. (24335148)	Kleffner I.... Schilling M.	2013
17	A case of Susac syndrome. (24082778)	Cho H.J.... Kim J.W.	2013
18	Progression of retinal artery occlusion from one eye to the other seems to be a characteristic finding in Susac syndrome. (24510092)	Yildirim Y.... Kaya A.	2013
19	Unilateral central retinal artery occlusion as the sole presenting sign of Susac syndrome in a young man: case report. (23929083)	dos ApA^stolos-Pereira S.L.... Monteiro M.L.	2013
20	A case of Susac syndrome with cervical spinal cord involvement on MRI. (24365248)	Hua L.H.... Okuda D.T.	2013
21	Susac syndrome: clinical characteristics and treatment in 29 new cases. (22221557)	Mateen F.J.... Petty G.W.	2012
22	A brief review of Susac syndrome. (22640902)	Kleffner I.... Ringelstein E.B.	2012
23	Exacerbation of Susac syndrome retinopathy by interferon Beta-1a. (22801853)	Laird P.W.... Yeh S.	2012
24	Susac syndrome and pregnancy: disease management. (21325959)	Deane K.D.... Striebich C.C.	2011
25	Recurrent bilateral branch retinal artery occlusion with hearing loss and encephalopathy: the first case report of Susac syndrome in Korea. (22065912)	Joe S.G.... Yoon Y.H.	2011
26	Review of Susac syndrome. (21897238)	Bitra R.K.... Eggenberger E.	2011
27	Gass plaques and fluorescein leakage in Susac Syndrome. (20880549)	Egan R.A.... Susac J.O.	2010
28	CT and MR imaging of Susac syndrome in a young male presenting with acute disorientation. (20189079)	Allmendinger A.M.... Destian S.	2010
29	Susac syndrome as an example of a rare vasculopathy. (19341183)	Olszanecka-Glinianowicz M.... Hrycek A.	2009
30	Case 142: Susac syndrome. (19188329)	Demir M.K.	2009
31	Is Susac syndrome (microangiopathy of the inner ear, retina, and central nervous system) an underdiagnosed cause of sensorineural hearing loss? (18633920)	Westreich R.... Chandrasekhar S.	2008
32	Diffusion tensor imaging demonstrates fiber impairment in Susac syndrome. (17959768)	Kleffner I.... Ringelstein E.B.	2008
33	Susac syndrome and vestibular-evoked myogenic potentials. (18359373)	Magliulo G.... Stasolla A.	2008
34	Susac syndrome in a patient with hepatitis C. (17414876)	Chawla A.... Doran M.	2007
35	Long-term outcome in Susac syndrome. (17435589)	Aubart-Cohen F.... Papo T.	2007
36	Re: Susac syndrome in four male patients. (18040266)	Lubow M.	2007
37	Susac syndrome in a young child. (17476496)	Eluvathingal Muttikkal T.J.... Keluth Chavan V.N.	2007
38	Susac syndrome in four male patients. (17151493)	Snyers B.... Sindic C.	2006
39	Susac syndrome with frontal intermittent rhythmic delta activity (FIRDA). (17168166)	Woolridge D.... Hoppe B.	2006
40	Treatment of Susac syndrome with gamma globulin and corticosteroids. (17052732)	Fox R.J.... Markowitz C.E.	2006
41	Susac syndrome: retinocochleocerebral vasculopathy. (15185430)	SzilasiovA! J.... KlA-movA! E.	2004
42	Susac syndrome: serial diffusion-weighted MR imaging. (15607101)	Xu M.S.... Lim C.C.	2004
43	Susac syndrome. (12439681)	Sandhya V.... Anand N.	2002
44	Susac syndrome and multiple sclerosis. (11296064)	Sirikci A.	2001
45	Susac syndrome: a vasospastic disorder? (11456021)	Flammer J.... Haufschild T.	2001
46	A case of Susac syndrome. (11057732)	Yellin M.W.... Johnson T.W.	2000
47	Susac syndrome. (10844072)	Murata Y.... Negi A.	2000
48	Microangiopathy of the inner ear, retina, and brain (Susac syndrome): report of a case. (10628717)	Ayache D.... Gout O.	2000
49	Susac syndrome: microangiopathy of the retina, cochlea and brain. (11097286)	Saw V.P.... Watson J.D.	2000
50	Microangiopathy of the brain, retina, and cochlea (Susac syndrome). A report of five cases and a review of the literature. (9627654)	O'Halloran H.S.... Berger J.R.	1998