MCID: SSC001
MIFTS: 24

Susac Syndrome malady

Rare diseases, Neuronal diseases, Ear diseases, Cardiovascular diseases categories

Aliases & Classifications for Susac Syndrome

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Sources:
41NIH Rare Diseases, 47Orphanet, 60UMLS, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Susac Syndrome, Aliases & Descriptions:

Name: Susac Syndrome 41 47 60
Retinopathy-Encephalopathy-Deafness Associated with Microangiopathy 41 47
Small Infarctions of Cochlear, Retinal and Encephalic Tissue 41 47
Retinocochleocerebral Vasculopathy 41 47
 
Sicret Syndrome 41 47
Red-M 41 47
Sicret Syndrome 41


Classifications:



Characteristics (Orphanet epidemiological data):

47
susac syndrome:
Age of onset: All ages; Age of death: normal life expectancy


External Ids:

Orphanet47 838
MESH via Orphanet34 D055955
ICD10 via Orphanet26 I67.7
UMLS via Orphanet61 C2717757

Summaries for Susac Syndrome

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NIH Rare Diseases:41 Susac syndrome is an autoimmune condition that affects very fine blood vessels in the brain, retina, and cochlea (inner ear). it is characterized by three main symptoms: encephalopathy (which can cause headache, mild memory loss, personality changes, and confusion); sensorineural hearing loss; and vision loss. most people do not have all the symptoms of susac syndrome at the beginning of their illness but develop symptoms over the course of several years. susac syndrome affects women more than men and the age of onset is usually between 20 and 40 years. the cause of this condition is still unknown. corticosteroids, antiplatelets, anticoagulation, and cyclophosphamide have been used to treat susac syndrome. however, the extent to which individuals respond to treatment is not clear. improvement may occur spontaneously although in some cases there may be residual dysfunction. last updated: 7/21/2014

MalaCards based summary: Susac Syndrome, also known as retinopathy-encephalopathy-deafness associated with microangiopathy, is related to retinitis and retinal artery occlusion. Affiliated tissues include brain, retina and eye.

Related Diseases for Susac Syndrome

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Diseases related to Susac Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
idRelated DiseaseScoreTop Affiliating Genes
1retinitis10.6
2retinal artery occlusion10.5
3central retinal artery occlusion10.4
4branch retinal artery occlusion10.2
5bipolar disorder10.1
6hepatitis10.1
7multifocal motor neuropathy10.1
8hepatitis c10.1
9cauda equina syndrome10.1
10retinal vasculitis10.1
11sensorineural hearing loss10.1
12cervicitis10.1
13neuropathy10.1
14vasculitis10.1
15central serous chorioretinopathy10.1
16endotheliitis10.1

Graphical network of diseases related to Susac Syndrome:



Diseases related to susac syndrome

Symptoms for Susac Syndrome

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Drugs & Therapeutics for Susac Syndrome

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Drug clinical trials:

Search ClinicalTrials for Susac Syndrome

Search NIH Clinical Center for Susac Syndrome

Genetic Tests for Susac Syndrome

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Anatomical Context for Susac Syndrome

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MalaCards organs/tissues related to Susac Syndrome:

31
Brain, Retina, Eye, Spinal cord, Endothelial

Animal Models for Susac Syndrome or affiliated genes

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Publications for Susac Syndrome

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Articles related to Susac Syndrome:

(show top 50)    (show all 81)
idTitleAuthorsYear
1
Do not forget susac syndrome in patients with unexplained acute confusion. (25680663)
2015
2
A case of susac syndrome. (25553231)
2015
3
Central Serous Chorioretinopathy in Susac Syndrome. (25786202)
2015
4
Update on Susac syndrome: new insights in brain and retinal imaging and treatment options. (24662104)
2014
5
Susac syndrome: diverse clinical findings and treatment. (25295909)
2014
6
Recurrence of Susac Syndrome following 23 Years of Remission. (24987361)
2014
7
What is Susac syndrome? - A brief review of articles. (25632332)
2014
8
Clinical, paraclinical and serological findings in Susac syndrome: an international multicenter study. (24606999)
2014
9
Unilateral central retinal artery occlusion as the sole presenting sign of Susac syndrome in a young man: case report. (24232952)
2013
10
Susac syndrome: an Italian case. (23828373)
2013
11
Characteristics of Susac syndrome: a review of all reported cases. (23628737)
2013
12
Susac Syndrome Treated with Subcutaneous Immunoglobulin. (24335148)
2013
13
A case of Susac syndrome. (24082778)
2013
14
Progression of retinal artery occlusion from one eye to the other seems to be a characteristic finding in Susac syndrome. (24510092)
2013
15
Unilateral central retinal artery occlusion as the sole presenting sign of Susac syndrome in a young man: case report. (23929083)
2013
16
A case of Susac syndrome with cervical spinal cord involvement on MRI. (24365248)
2013
17
Susac syndrome in a patient with human immunodeficiency virus infection. (23690260)
2013
18
Reply: Progression of retinal artery occlusion in Susac syndrome. (24510093)
2013
19
Reply: Fibrin-like material in the retinal arterioles and fluorescein angiography findings in Susac syndrome. (24232953)
2013
20
Susac syndrome: clinical characteristics and treatment in 29 new cases. (22221557)
2012
21
A brief review of Susac syndrome. (22640902)
2012
22
Exacerbation of Susac syndrome retinopathy by interferon Beta-1a. (22801853)
2012
23
Susac syndrome and pregnancy: disease management. (21325959)
2011
24
Recurrent bilateral branch retinal artery occlusion with hearing loss and encephalopathy: the first case report of Susac syndrome in Korea. (22065912)
2011
25
Review of Susac syndrome. (21897238)
2011
26
Gass plaques and fluorescein leakage in Susac Syndrome. (20880549)
2010
27
CT and MR imaging of Susac syndrome in a young male presenting with acute disorientation. (20189079)
2010
28
Susac syndrome as an example of a rare vasculopathy. (19341183)
2009
29
Case 142: Susac syndrome. (19188329)
2009
30
Is Susac syndrome (microangiopathy of the inner ear, retina, and central nervous system) an underdiagnosed cause of sensorineural hearing loss? (18633920)
2008
31
Diffusion tensor imaging demonstrates fiber impairment in Susac syndrome. (17959768)
2008
32
Susac syndrome and vestibular-evoked myogenic potentials. (18359373)
2008
33
Susac syndrome in a patient with hepatitis C. (17414876)
2007
34
Long-term outcome in Susac syndrome. (17435589)
2007
35
Re: Susac syndrome in four male patients. (18040266)
2007
36
Susac syndrome in a young child. (17476496)
2007
37
Susac syndrome in four male patients. (17151493)
2006
38
Susac syndrome with frontal intermittent rhythmic delta activity (FIRDA). (17168166)
2006
39
Treatment of Susac syndrome with gamma globulin and corticosteroids. (17052732)
2006
40
Susac syndrome: retinocochleocerebral vasculopathy. (15185430)
2004
41
Susac syndrome: serial diffusion-weighted MR imaging. (15607101)
2004
42
Evolution of lesions in Susac syndrome at serial MR imaging with diffusion-weighted imaging and apparent diffusion coefficient values. (15140708)
2004
43
Susac syndrome. (12439681)
2002
44
Susac syndrome and multiple sclerosis. (11296064)
2001
45
Susac syndrome: a vasospastic disorder? (11456021)
2001
46
A case of Susac syndrome. (11057732)
2000
47
Susac syndrome. (10844072)
2000
48
Microangiopathy of the inner ear, retina, and brain (Susac syndrome): report of a case. (10628717)
2000
49
Susac syndrome: microangiopathy of the retina, cochlea and brain. (11097286)
2000
50
Microangiopathy of the brain, retina, and cochlea (Susac syndrome). A report of five cases and a review of the literature. (9627654)
1998

Variations for Susac Syndrome

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Expression for genes affiliated with Susac Syndrome

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Search GEO for disease gene expression data for Susac Syndrome.

Pathways for genes affiliated with Susac Syndrome

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Compounds for genes affiliated with Susac Syndrome

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GO Terms for genes affiliated with Susac Syndrome

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Products for genes affiliated with Susac Syndrome

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Sources for Susac Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet