MCID: SWT001
MIFTS: 41

Sweat Gland Carcinoma malady

Cancer diseases, Endocrine diseases categories

Aliases & Classifications for Sweat Gland Carcinoma

About this section

Aliases & Descriptions for Sweat Gland Carcinoma:

Name: Sweat Gland Carcinoma 10 65
Malignant Neoplasm of Sweat Gland 10 65
Sweat Gland Neoplasms 65 36
Primary Malignant Neoplasm of Sweat Gland 65
Malignant Tumor of the Sweat Gland 10
Carcinoma of the Sweat Gland 10
Sweat Gland Adenocarcinoma 65
 
Tumor of the Sweat Gland 10
Neoplasm of Sweat Gland 10
Sweat Gland Tumor Nos 10
Sweat Gland Neoplasm 10
Sweat Gland Cancer 10
Sweat Gland Tumor 10


Classifications:



Summaries for Sweat Gland Carcinoma

About this section
MalaCards based summary: Sweat Gland Carcinoma, also known as malignant neoplasm of sweat gland, is related to apocrine sweat gland neoplasm and breast cancer. An important gene associated with Sweat Gland Carcinoma is KRT20 (Keratin 20, Type I), and among its related pathways are Cytoskeletal Signaling and Glucocorticoid receptor regulatory network. Affiliated tissues include breast, skin and lymph node, and related mouse phenotypes are limbs/digits/tail and no phenotypic analysis.

Related Diseases for Sweat Gland Carcinoma

About this section

Diseases related to Sweat Gland Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 350)
idRelated DiseaseScoreTop Affiliating Genes
1apocrine sweat gland neoplasm30.7ERBB2, MUC1, PGR, PIP
2breast cancer28.4ERBB2, ESR1, KRT14, KRT20, KRT5, KRT7
3eccrine sweat gland cancer10.4
4oral leukoedema10.4KRT20, KRT7
5vulva basal cell carcinoma10.4KRT20, KRT7
6plexiform neurofibroma10.4KRT20, KRT7
7qazi markouizos syndrome10.4KRT20, KRT7
8placental choriocarcinoma10.4KRT20, KRT7
9cloacogenic carcinoma10.3KRT20, KRT7
10splenic artery aneurysm10.3MUC1, PGR
11chronic cholangitis10.3KRT20, KRT7
12null-cell leukemia10.3KRT20, KRT7
13vaginal benign neoplasm10.3KRT20, KRT7
14vaginal cancer10.3KRT20, KRT7
15aggressive digital papillary adenocarcinoma10.3
16papillary adenocarcinoma10.3
17synovial angioma10.3KRT20, KRT7
18dyschromatosis universalis10.3KRT7, KRT8
19endomyocardial fibroelastosis10.3KRT7, KRT8
20bicervical bicornuate uterus and blind hemivagina10.3KRT20, KRT7
21spiradenoma10.3
22residual stage of open angle glaucoma10.3KRT20, MUC1
23hepatic flexure cancer10.3KRT20, KRT7
24cowpox10.3KRT20, KRT7
25eccrine acrospiroma10.3
26hepatorenal syndrome10.3KRT20, KRT7
27malignant teratocarcinosarcoma10.3MUC1, PGR
28paralytic poliomyelitis10.3KRT20, MUC1
29endometriosis of intestine10.3MUC1, PGR
30supraglottic laryngeal cancer10.3KRT20, PIP
31benign multicystic peritoneal mesothelioma10.3KRT7, PGR
32dermal unilateral segmental cavernous angioma10.3KRT20, KRT8
33sinus cancer10.3MUC1, SYP
34renal pelvis transitional cell carcinoma10.3KRT20, KRT7
35cervical incompetence10.3MUC1, SYP
36verrucous carcinoma10.3MUC1, TP53
37vulvar nodular hidradenoma10.3MUC1, PIP
38ophthalmia neonatorum10.3MUC1, SYP
39intrahepatic bile duct adenoma10.3PGR, PIP
40congenital adrenal hyperplasia10.3PGR, SYP
41seminal vesicle tumor10.3PGR, SYP
42spindle cell liposarcoma10.3KRT8, MUC1
43cowden disease10.3PGR, TP53
44bladder squamous cell carcinoma10.3KRT20, TP53
45mixed gonadal dysgenesis10.3MUC1, SYP
46ampulla of vater carcinoma10.3KRT20, MUC1
47calloso-genital dysplasia10.3KRT8, TP53
48urogenital tuberculosis10.3KRT20, TP53
49basal cell carcinoma 710.3MUC1, TP53
50bile duct carcinoma10.3KRT20, KRT7, MUC1

Graphical network of the top 20 diseases related to Sweat Gland Carcinoma:



Diseases related to sweat gland carcinoma

Symptoms for Sweat Gland Carcinoma

About this section

Drugs & Therapeutics for Sweat Gland Carcinoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Sweat Gland Carcinoma


Cochrane evidence based reviews: Sweat Gland Neoplasms

Genetic Tests for Sweat Gland Carcinoma

About this section

Anatomical Context for Sweat Gland Carcinoma

About this section

MalaCards organs/tissues related to Sweat Gland Carcinoma:

33
Breast, Skin, Lymph node, Lung, Kidney, Bone, Salivary gland

Animal Models for Sweat Gland Carcinoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Sweat Gland Carcinoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.3ERBB2, ESR1, KRT5, PGR, TP53
2MP:00030128.1ESR1, KRT5, MUC1, PGR, SYP, TP53
3MP:00053897.3ERBB2, ESR1, KRT14, KRT8, PGR, PIP
4MP:00020067.1ERBB2, ESR1, KRT14, MUC1, PGR, TP53
5MP:00107716.9ERBB2, ESR1, KRT14, KRT5, MUC1, PGR
6MP:00053816.7ERBB2, ESR1, KRT14, KRT5, KRT8, MUC1

Publications for Sweat Gland Carcinoma

About this section

Articles related to Sweat Gland Carcinoma:

(show top 50)    (show all 126)
idTitleAuthorsYear
1
Merkel cell carcinoma with glandular differentiation admixed with sweat gland carcinoma and spindle cell carcinoma: histogenesis of merkel cell carcinoma from hair follicle stem cells. (25699980)
2015
2
Primary Cutaneous Endocrine Mucin-Producing Sweat Gland Carcinoma Co-occurring Simultaneously With Low-Grade Ductal Mucinous Breast Cancer: A Clinicopathologic Conundrum. (25014107)
2014
3
Considerations before accepting an extra-facial location of endocrine mucin-producing sweat gland carcinoma. (25487867)
2014
4
Primary cutaneous sweat gland carcinoma. (25022402)
2014
5
Aggressiveness of poorly differentiated sweat gland carcinoma in kidney transplant recipient. (23829827)
2013
6
Mucin-producing sweat gland carcinoma of the eyelid: diagnostic and prognostic considerations. (23218693)
2013
7
Apocrine sweat gland carcinoma: initial evaluation, staging, and response monitoring using 18F-FDG PET/CT. (23377411)
2013
8
Endocrine mucin producing sweat gland carcinoma: a clinicopathological analysis of three cases. (22935981)
2012
9
Clinicopathologic characteristics of 12 patients with vulvar sweat gland carcinoma. (20606537)
2010
10
Sweat gland carcinoma - a case report. (21661469)
2010
11
Endocrine mucin-producing sweat gland carcinoma: report of a case and review of the literature. (17177942)
2006
12
Sweat gland carcinoma with lung metastases. (17998708)
2006
13
Endocrine mucin-producing sweat gland carcinoma: twelve new cases suggest that it is a precursor of some invasive mucinous carcinomas. (16160476)
2005
14
Treatment of synchronous mucinous carcinoma and endocrine mucin-producing sweat gland carcinoma with Mohs' micrographic surgery. (15841644)
2005
15
Sweat gland carcinoma. (14964551)
2004
16
Recurrent polymorphous sweat gland carcinoma of the skin. (12063490)
2002
17
Histiocytoid variant of eccrine sweat gland carcinoma of the eyelid and orbit: report of five cases. (11874761)
2002
18
Facial sweat gland carcinoma metastasizing to neck nodes: a diagnostic and therapeutic challenge. (11735822)
2001
19
Metastatic sweat gland carcinoma. (11762625)
2001
20
Apocrine sweat gland carcinoma. (11339615)
2001
21
Malignant apocrine sweat gland carcinoma of the caruncle. (12045959)
2000
22
Sweat gland carcinoma with multiple local recurrences: a case report. (10655575)
1999
23
Epidermal growth factor, estrogen, and progesterone receptor expression in primary sweat gland carcinomas and primary and metastatic mammary carcinomas. (10463481)
1999
24
Sweat gland carcinoma: a clinicopathologic analysis of an expanded series in a single institution. (9727435)
1998
25
Endocrine mucin-producing sweat gland carcinoma: a cutaneous neoplasm analogous to solid papillary carcinoma of breast. (9414195)
1997
26
Sweat gland carcinoma. (9149787)
1997
27
Sweat gland carcinoma in a human immunodeficiency virus-infected patient. (7539911)
1995
28
Prognostic value of immunohistochemical staining for proliferating cell nuclear antigen, p53, and c-erbB-2 in sebaceous gland carcinoma and sweat gland carcinoma: comparison with histopathological parameter. (7909154)
1994
29
A case of ductal sweat gland carcinoma connected to syringocystadenoma papilliferum arising in nevus sebaceus. (7699123)
1994
30
Giant primary mucinous sweat gland carcinoma of the scalp. (8403482)
1993
31
Sweat gland carcinoma with mucinous and infiltrating duct-like patterns. (1331212)
1992
32
Sweat gland carcinoma ex eccrine spiradenoma. (2847574)
1987
33
Mucinous (adenocystic) sweat gland carcinoma of the great toe. (2833541)
1987
34
Inguinal sweat gland carcinoma with choriocarcinomatous differentiation. (2425551)
1986
35
Axillary sweat gland carcinoma versus amelanotic malignant melanoma. (4089996)
1985
36
Extramammary Paget's disease. Arising in knee region in association with sweat gland carcinoma. (6205637)
1984
37
Metastasizing eccrine sweat gland carcinoma. Report of a case. (6721544)
1984
38
Sweat gland carcinoma with hypercalcemia. (7132372)
1982
39
Primary mucinous sweat gland carcinoma of the eyelid simulating metastatic carcinoma. (219696)
1979
40
Sustained complete remission of metastatic sweat gland carcinoma following regional hyperthermic perfusion. (660813)
1978
41
Metastatic sweat gland carcinoma. (703462)
1978
42
Sweat gland carcinoma: a clinico-pathological reappraisal. (1249938)
1976
43
Sweat gland carcinoma. Report of a case in an unusual location and review of literature. (4823258)
1974
44
Sweat gland carcinoma of the hand. (4825405)
1974
45
Sweat gland carcinoma arising in irradiated skin. (5011405)
1972
46
Sweat gland carcinoma: a clinico-pathologic study of 83 patients. (5100098)
1971
47
Apocrine sweat gland carcinoma. Report of a case. (5476740)
1970
48
APOCRINE GLAND CARCINOMA (SWEAT GLAND CARCINOMA) OF THE BREAST. (14119212)
1964
49
Metastasizing sweat-gland carcinoma; notes on the surgical therapy. (13636656)
1959
50
Sweat-gland carcinoma of eyelid. (14430109)
1959

Variations for Sweat Gland Carcinoma

About this section

Expression for genes affiliated with Sweat Gland Carcinoma

About this section
Search GEO for disease gene expression data for Sweat Gland Carcinoma.

Pathways for genes affiliated with Sweat Gland Carcinoma

About this section

Pathways related to Sweat Gland Carcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.2KRT20, KRT5, KRT7, KRT8
29.1KRT14, KRT5, TP53
39.1ERBB2, MUC1, TP53
49.0ESR1, KRT8, TP53
5
Show member pathways
8.8KRT14, KRT5, KRT7, KRT8

GO Terms for genes affiliated with Sweat Gland Carcinoma

About this section

Cellular components related to Sweat Gland Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:00450959.4KRT14, KRT5, KRT7, KRT8
2intermediate filamentGO:00058828.7KRT14, KRT15, KRT20, KRT5, KRT7, KRT8
3nucleusGO:00056346.1ERBB2, ESR1, KRT14, KRT15, KRT5, KRT7

Biological processes related to Sweat Gland Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:00069789.8MUC1, TP53
2hemidesmosome assemblyGO:00315819.4KRT14, KRT5
3epidermis developmentGO:00085448.7KRT14, KRT15, KRT5

Molecular functions related to Sweat Gland Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:00971109.9KRT15, KRT5, KRT8
2structural constituent of cytoskeletonGO:00052008.6KRT14, KRT15, KRT20, KRT5
3structural molecule activityGO:00051988.6KRT14, KRT15, KRT20, KRT5, KRT7, KRT8
4protein bindingGO:00055155.0ERBB2, ESR1, KRT14, KRT15, KRT20, KRT5

Sources for Sweat Gland Carcinoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet