MCID: SWN001
MIFTS: 43

Swine Influenza malady

Respiratory diseases category

Summaries for Swine Influenza

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8Disease Ontology, 3CDC, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An influenza that results in infection located in respiratory tract of pigs and humans, has material basis in influenza c virus, or has material basis in influenza a virus subtypes (h1n1, h1n2, h3n1, h3n2, and h2n3), which are transmitted by direct contact with infected pigs. the infection in humans has symptom fever, has symptom lethargy, has symptom lack of appetite, has symptom coughing, has symptom runny nose, has symptom sore throat, has symptom nausea, has symptom vomiting, and has symptom diarrhea.

MalaCards: Swine Influenza, also known as influenza due to influenza a virus subtype h1n1, is related to influenza and avian influenza, and has symptoms including diarrhea, vomiting and nausea. An important gene associated with Swine Influenza is NEU1 (sialidase 1 (lysosomal sialidase)). The compounds mannose and alanine have been mentioned in the context of this disorder. Affiliated tissues include respiratory tract of pigs, testes and lung.

CDC:3 Swine influenza (swine flu) is a respiratory disease of pigs caused by type A influenza viruses that regularly cause outbreaks of influenza in pigs. Influenza viruses that commonly circulate in swine are called “swine influenza viruses” or “swine flu viruses.” Like human influenza viruses, there are different subtypes and strains of swine influenza viruses. The main swine influenza viruses circulating in U.S. pigs in recent years are:

Wikipedia:63 Swine influenza, also called pig influenza, swine flu, hog flu and pig flu, is an infection caused by... more...

Aliases & Classifications for Swine Influenza

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8Disease Ontology, 44Novoseek, 60UMLS, 25ICD10
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Related Diseases for Swine Influenza

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17GeneCards, 18GeneDecks
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Diseases related to Swine Influenza via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 29)
idRelated DiseaseScoreTop Affiliating Genes
1influenza32.1NEU1
2avian influenza10.8
3pneumonia10.8
4cerebritis10.2
5systemic lupus erythematosus10.2
6legionnaires' disease10.2
7lupus erythematosus10.2
8lymphopenia10.2
9respiratory failure10.2
10pleuropneumonia10.1
11narcolepsy10.1
12vaccinia10.1
13brain edema10.1
14viral pneumonia10.1
15appendicitis10.1
16chronic fatigue syndrome10.1
17arthritis10.1
18hematologic cancer10.1
19mouth disease10.1
20myocardial infarction10.1
21myocarditis10.1
22neuropathy10.1
23optic atrophy10.1
24plague10.1
25rheumatoid arthritis10.1
26thrombocytopenia10.1
27vesiculitis10.0GP2
28hemolytic anemia10.0NEU1, SLC4A1
29primary hyperoxaluria10.0SLC4A1, TREH, NEU1

Graphical network of the top 20 diseases related to Swine Influenza:



Diseases related to swine influenza

Clinical Features for Swine Influenza

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8Disease Ontology
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Symptoms:

8 (show all 9)
  • diarrhea
  • vomiting
  • nausea
  • sore throat
  • runny nose
  • coughing
  • lack of appetite
  • lethargy
  • fever

Drugs & Therapeutics for Swine Influenza

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Swine Influenza

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Anatomical Context for Swine Influenza

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Swine Influenza:

32
Testes, Lung, T cells, Brain, Bone, Bone marrow

FMA organs/tissues related to Swine Influenza:

14
Respiratory tract of pigs

Animal Models for Swine Influenza or affiliated genes

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Publications for Swine Influenza

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50PubMed
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Articles related to Swine Influenza:

(show top 50)    (show all 515)
idTitleAuthorsYear
1
Immunization of pigs with an attenuated pseudorabies virus recombinant expressing the hemagglutinin of pandemic swine origin H1N1 influenza A virus. (24431235)
2014
2
Comparative analysis of receptor-binding specificity and pathogenicity in natural reassortant and non-reassortant H3N2 swine influenza virus. (24305615)
2014
3
In hospitalized adults the combined presence of leukocytosis, relative lymphopenia, and thrombocytopenia is predictive of swine influenza (H1N1). (23911963)
2013
4
Isolation of a novel swine influenza virus from Oklahoma in 2011 which is distantly related to human influenza C viruses. (23408893)
2013
5
Dynamics of influenza A virus infections in permanently infected pig farms: evidence of recurrent infections, circulation of several swine influenza viruses and reassortment events. (24007505)
2013
6
Genetic and biological characterisation of an avian-like H1N2 swine influenza virus generated by reassortment of circulating avian-like H1N1 and H3N2 subtypes in Denmark. (24047399)
2013
7
Clinicopathological features of Swine influenza. (23404579)
2013
8
Awareness and practices regarding zoonotic influenza prevention in Romanian swine workers. (24224817)
2013
9
Enhanced replication of swine influenza viruses in dexamethasone-treated juvenile and layer turkeys. (23123174)
2013
10
Capsular sialic acid of Streptococcus suis serotype 2 binds to swine influenza virus and enhances bacterial interactions with virus-infected tracheal epithelial cells. (24082069)
2013
11
Precise H1N1 swine influenza detection using stuffer-free multiplex ligation-dependent probe amplification in conformation-sensitive capillary electrophoresis. (22342882)
2012
12
Virus survival in slurry: analysis of the stability of foot-and-mouth disease, classical swine fever, bovine viral diarrhoea and swine influenza viruses. (22226541)
2012
13
Naturally occurring swine influenza A virus PB1-F2 phenotypes that contribute to superinfection with Gram-positive respiratory pathogens. (22674997)
2012
14
Molecular characterization and pathogenicity of swine influenza H9N2 subtype virus A/swine/HeBei/012/2008/(H9N2). (21978155)
2011
15
Reassortment events among swine influenza A viruses in China: implications for the origin of the 2009 influenza pandemic. (21795347)
2011
16
Seroconversion to pandemic (H1N1) 2009 virus and cross-reactive immunity to other swine influenza viruses. (22000365)
2011
17
Identification and characterization of H2N3 avian influenza virus from backyard poultry and comparison with novel H2N3 swine influenza virus. (22312981)
2011
18
Immunogenicity and protective efficacy of an elastase-dependent live attenuated swine influenza virus vaccine administered intranasally in pigs. (20708697)
2010
19
Reassortment between swine influenza A viruses increased their adaptation to humans in pandemic H1N1/09. (20117250)
2010
20
Swine influenza vaccines: current status and future perspectives. (20462470)
2010
21
Swine influenza A (H1N1) strikes a potential for global disaster. (19561969)
2009
22
Life-threatening respiratory failure from H1N1 influenza 09 (human swine influenza). (19645645)
2009
23
Against the new H1N1 influenza (swine influenza): vaccinate or don't vaccinate (all)? That is currently the question! (19768383)
2009
24
Population dynamics of swine influenza virus in farrow-to-finish and specialised finishing herds in the Netherlands. (19181461)
2009
25
Human swine influenza A [H1N1]: practical advice for clinicians early in the pandemic. (19651387)
2009
26
Homologous recombination evidence in human and swine influenza A viruses. (18721995)
2008
27
Rapid microchip-based electrophoretic immunoassays for the detection of swine influenza virus. (18651074)
2008
28
Swine influenza (H3N2) infection in a child and possible community transmission, Canada. (18258037)
2007
29
An ethicist's commentary on using compounded aspirin versus licensed drugs on swine influenza. (16536226)
2006
30
First outbreak of respiratory disease associated with swine influenza H1N2 virus in pigs in Korea. (15825500)
2005
31
Evaluation of the ESPLINE INFLUENZA A&B-N Kit for the diagnosis of avian and swine influenza. (16365531)
2005
32
Exposure of sero-positive gilts to swine influenza virus may cause a few stillbirths per litter. (15352547)
2004
33
The emergence of novel swine influenza viruses in North America. (12034486)
2002
34
H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes. (11867515)
2002
35
Genomic analysis of matrix gene and antigenic studies of its gene product (M1) of a swine influenza virus (H1N1) causing chronic respiratory disease in pigs. (11129631)
2000
36
Genomic study of hemagglutinins of swine influenza (H1N1) viruses associated with acute and chronic respiratory diseases in pigs. (9125053)
1997
37
Pathogenicity of concurrent infection of pigs with porcine respiratory coronavirus and swine influenza virus. (1334565)
1992
38
Antigenic variant of swine influenza virus causing proliferative and necrotizing pneumonia in pigs. (1333815)
1992
39
Swine influenza virus infections. Transmission from ill pigs to humans at a Wisconsin agricultural fair and subsequent probable person-to-person transmission. (1845913)
1991
40
Reassessment of the association between Guillain-BarrAc syndrome and receipt of swine influenza vaccine in 1976-1977: results of a two-state study. Expert Neurology Group. (1851395)
1991
41
Response of calves to exposure with swine influenza virus. (2820279)
1987
42
Outbreaks of classical swine influenza in pigs in England in 1986. (2820111)
1987
43
Responses of cattle, sheep and poultry to a recombinant vaccinia virus expressing a swine influenza haemagglutinin. (3764100)
1986
44
Ultrastructural morphometric investigation of early lesions in the pulmonary alveolar region of pigs during experimental swine influenza infection. (3006499)
1986
45
The swine influenza vaccination controversy. (4051841)
1985
46
Statistical analysis of results of a survey on antibody against swine influenza virus in pigs by single radial hemolysis and hemagglutination-inhibition tests. (7078660)
1982
47
The epidemiology and ecology of swine influenza as a zoonotic disease. (6258844)
1980
48
Influenza HI antibodies in pig and man in Malaysia (with special reference to swine influenza). (548720)
1979
49
Swine influenza: lessons learned. (83459)
1978
50
Outbreaks of classical swine influenza in Italy in 1976. (217205)
1978

Genetic Variations for Swine Influenza

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Expression for genes affiliated with Swine Influenza

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Swine Influenza

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Pathways for genes affiliated with Swine Influenza

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Compounds for genes affiliated with Swine Influenza

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44Novoseek
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Compounds related to Swine Influenza according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1mannose449.3SLC4A1, NEU1
2alanine448.9SLC4A1, RNASEH1, TREH

GO Terms for genes affiliated with Swine Influenza

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Products for genes affiliated with Swine Influenza

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Swine Influenza

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet