MCID: SWN001
MIFTS: 43

Swine Influenza malady

Respiratory diseases category

Summaries for Swine Influenza

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8Disease Ontology, 3CDC, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An influenza that results in infection located in respiratory tract of pigs and humans, has material basis in influenza c virus, or has material basis in influenza a virus subtypes (h1n1, h1n2, h3n1, h3n2, and h2n3), which are transmitted by direct contact with infected pigs. the infection in humans has symptom fever, has symptom lethargy, has symptom lack of appetite, has symptom coughing, has symptom runny nose, has symptom sore throat, has symptom nausea, has symptom vomiting, and has symptom diarrhea.

MalaCards: Swine Influenza, also known as influenza due to influenza a virus subtype h1n1, is related to influenza and avian influenza, and has symptoms including diarrhea, vomiting and nausea. An important gene associated with Swine Influenza is NEU1 (sialidase 1 (lysosomal sialidase)). The compounds mannose and alanine have been mentioned in the context of this disorder. Affiliated tissues include respiratory tract of pigs, testes and lung.

CDC:3 Swine influenza (swine flu) is a respiratory disease of pigs caused by type A influenza viruses that regularly cause outbreaks of influenza in pigs. Influenza viruses that commonly circulate in swine are called “swine influenza viruses” or “swine flu viruses.” Like human influenza viruses, there are different subtypes and strains of swine influenza viruses. The main swine influenza viruses circulating in U.S. pigs in recent years are:

Wikipedia:63 Swine influenza, also called pig influenza, swine flu, hog flu and pig flu, is an infection caused by... more...

Aliases & Classifications for Swine Influenza

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8Disease Ontology, 44Novoseek, 60UMLS, 25ICD10
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Related Diseases for Swine Influenza

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17GeneCards, 18GeneDecks
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Diseases related to Swine Influenza via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 29)
idRelated DiseaseScoreTop Affiliating Genes
1influenza32.1NEU1
2avian influenza10.8
3pneumonia10.8
4cerebritis10.2
5systemic lupus erythematosus10.2
6legionnaires' disease10.2
7lupus erythematosus10.2
8lymphopenia10.2
9respiratory failure10.2
10pleuropneumonia10.1
11narcolepsy10.1
12vaccinia10.1
13brain edema10.1
14viral pneumonia10.1
15appendicitis10.1
16chronic fatigue syndrome10.1
17arthritis10.1
18hematologic cancer10.1
19mouth disease10.1
20myocardial infarction10.1
21myocarditis10.1
22neuropathy10.1
23optic atrophy10.1
24plague10.1
25rheumatoid arthritis10.1
26thrombocytopenia10.1
27vesiculitis10.0GP2
28hemolytic anemia10.0NEU1, SLC4A1
29primary hyperoxaluria10.0SLC4A1, TREH, NEU1

Graphical network of the top 20 diseases related to Swine Influenza:



Diseases related to swine influenza

Clinical Features for Swine Influenza

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8Disease Ontology
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Symptoms:

8 (show all 9)
  • diarrhea
  • vomiting
  • nausea
  • sore throat
  • runny nose
  • coughing
  • lack of appetite
  • lethargy
  • fever

Drugs & Therapeutics for Swine Influenza

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Swine Influenza

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Anatomical Context for Swine Influenza

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Swine Influenza:

32
Testes, Lung, T cells, Brain, Bone, Bone marrow

FMA organs/tissues related to Swine Influenza:

14
Respiratory tract of pigs

Animal Models for Swine Influenza or affiliated genes

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Publications for Swine Influenza

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50PubMed
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Articles related to Swine Influenza:

(show top 50)    (show all 515)
idTitleAuthorsYear
1
Genesis and genetic constellations of swine influenza viruses in Thailand. (24095146)
2013
2
Swine influenza virus vaccines: to change or not to change-that's the question. (22976350)
2013
3
Subcellular proteomic analysis of human host cells infected with H3N2 swine influenza virus. (24115376)
2013
4
Phylogeography of swine influenza H3N2 in the United States: translational public health for zoonotic disease surveillance. (23137647)
2013
5
Implications of narcolepsy link with swine-influenza vaccine. (23755397)
2013
6
Swine, human or avian influenza viruses differentially activates porcine dendritic cells cytokine profile. (23689011)
2013
7
Swine Influenza in Sub-Saharan Africa - Current Knowledge and Emerging Insights. (23826898)
2013
8
An eight-segment swine influenza virus harboring H1 and H3 hemagglutinins is attenuated and protective against H1N1 and H3N2 subtypes in pigs. (23843633)
2013
9
Retraction. Triple reassortant swine influenza A (H3N2) virus in waterfowl. (23260489)
2013
10
Swine influenza: clinical, serological, pathological, and virological cross-sectional studies in nine farms in Argentina. (24224814)
2013
11
Imported pigs may have introduced the first classical swine influenza viruses into Mainland China. (23567818)
2013
12
Emergence of novel reassortant H3N2 swine influenza viruses with the 2009 pandemic H1N1 genes in the United States. (22198410)
2012
13
Genome sequence of a monoreassortant H1N1 swine influenza virus isolated from a pig in Hungary. (23118459)
2012
14
Isolation and phylogenetic analysis of avian-origin European H1N1 swine influenza viruses in Jiangsu, China. (22198611)
2012
15
Seroprevalence and risk factors for swine influenza zoonotic transmission in swine workers from northwestern Mexico. (21801341)
2012
16
Migration of the swine influenza virus I'-cluster hemagglutinin N-linked glycosylation site from N142 to N144 results in loss of antibody cross-reactivity. (22815146)
2012
17
Isolation and Phylogenetic Analysis of H1N1 Swine Influenza Virus from Sick Pigs in Southern China. (23637505)
2011
18
Swine influenza (H1N1) pneumonia in hospitalized adults: chest film findings. (21545936)
2011
19
Severe swine influenza A (H1N1) versus severe human seasonal influenza A (H3N2): clinical comparisons. (21545937)
2011
20
Long-term evolution and transmission dynamics of swine influenza A virus. (21614079)
2011
21
Antigenic categorization of contemporary H3N2 Swine influenza virus isolates using a high-throughput serum neutralization assay. (20453207)
2010
22
Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distribution. (20158900)
2010
23
The pandemic 2009 (H1N1) swine influenza virus is mild compared to the pandemic 1918 (H1N1) virus because of a proline-to-serine substitution in the receptor-binding site of its hemagglutinin - a hypothesis. (19819081)
2010
24
Legionnaires' disease mimicking swine influenza (H1N1) pneumonia during the "herald wave" of the pandemic. (20457347)
2010
25
Occurrence of a pig respiratory disease associated with swine influenza A (H1N2) virus in Tochigi Prefecture, Japan. (20035121)
2010
26
Swine influenza (H1N1) pneumonia: elevated serum procalcitonin levels not due to superimposed bacterial pneumonia. (20188520)
2010
27
Swine influenza H1N1 virus induces acute inflammatory immune responses in pig lungs: a potential animal model for human H1N1 influenza virus. (20719941)
2010
28
Human infection with a triple-reassortant swine influenza A(H1N1) virus containing the hemagglutinin and neuraminidase genes of seasonal influenza virus. (20199242)
2010
29
Summary of the Australasian Society for Infectious Diseases and the Thoracic Society of Australia and New Zealand guidelines: treatment and prevention of H1N1 influenza 09 (human swine influenza) with antiviral agents. (19645641)
2009
30
Genetic and antigenic evolution of swine influenza viruses in Europe and evaluation of their zoonotic potential. (19497089)
2009
31
Swine influenza. (19433408)
2009
32
Swine influenza H1N1. Is your laboratory prepared? (19617998)
2009
33
Genetic diversity of swine influenza viruses isolated from pigs during 2000 to 2005 in Thailand. (19453423)
2008
34
A recombinant pseudorabies virus encoding the HA gene from H3N2 subtype swine influenza virus protects mice from virulent challenge. (16621018)
2006
35
Receptor-binding properties of swine influenza viruses isolated and propagated in MDCK cells. (15996787)
2005
36
Comparison of a commercial enzyme-linked immunosorbent assay with hemagglutination inhibition assay for serodiagnosis of swine influenza virus (H1N1) infection. (14974854)
2004
37
Antigenic and genetic diversity among swine influenza A H1N1 and H1N2 viruses in Europe. (11907321)
2002
38
Detection and subtyping of swine influenza H1N1, H1N2 and H3N2 viruses in clinical samples using two multiplex RT-PCR assays. (11879692)
2002
39
Herd-level seroprevalence of swine-influenza virus in Korea. (11937238)
2002
40
Comparison of embryonated chicken eggs with MDCK cell culture for the isolation of swine influenza virus. (11989733)
2002
41
An immunoperoxidase monolayer assay for the detection of antibodies against swine influenza virus. (11939342)
2002
42
Antigenic conservation of H1N1 swine influenza viruses. (2558159)
1989
43
Hemagglutinin polymorphism as the basis for low- and high-yield phenotypes of swine influenza virus. (3174662)
1988
44
Swine influenza vaccine and Guillain-BarrAc syndrome: lies, damn lies, and ... (3753271)
1986
45
Epidemiological study of swine influenza virus as a component of the respiratory disease complex of feeder calves. (3517990)
1986
46
Guillain-BarrAc syndrome and its relationship to swine influenza vaccination in Michigan, 1976-1977. (6731430)
1984
47
Isolation of viruses antigenically related to the swine influenza virus from an outbreak of respiratory disease in turkey farms in Israel. (6328732)
1984
48
Monoclonal antibodies to the hemagglutinin Sa antigenic site of a/pr/8/34 influenza virus distinguish biologic mutants of swine influenza virus. (6194531)
1983
49
Surveillance of the swine influenza vaccination program at the Royal Military College, Kingston. (657050)
1978
50
Investigations on the involvement of swine influenza A virus (Hsw1N1) in the influenza outbreak recorded in a town of Romania during the 1976--1977 winter season. (567886)
1978

Genetic Variations for Swine Influenza

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Expression for genes affiliated with Swine Influenza

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Swine Influenza

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Pathways for genes affiliated with Swine Influenza

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Compounds for genes affiliated with Swine Influenza

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44Novoseek
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Compounds related to Swine Influenza according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1mannose449.3SLC4A1, NEU1
2alanine448.9SLC4A1, RNASEH1, TREH

GO Terms for genes affiliated with Swine Influenza

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Products for genes affiliated with Swine Influenza

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Swine Influenza

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet