MCID: SYR002
MIFTS: 42

Syringocystadenoma Papilliferum malady

Categories: Rare diseases, Skin diseases, Cancer diseases

Aliases & Classifications for Syringocystadenoma Papilliferum

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Sources:
65UMLS, 10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Syringocystadenoma Papilliferum:

Name: Syringocystadenoma Papilliferum 10 45 12 51 65
Fistulous Vegetative Verrucous Hydradenoma 45 51
Naevus Syringocystadenomatosus Papilliferus 51
Syringadenoma Papilliferum 51
 
Papillary Syringadenoma 10
Papillary Hidradenoma 65
Scap 51

Characteristics:

Orphanet epidemiological data:

51
syringocystadenoma papilliferum:
Inheritance: Not applicable; Age of onset: Childhood

Classifications:



External Ids:

Disease Ontology10 DOID:5445
NCIt42 C4172
Orphanet51 840
SNOMED-CT59 239121009, 8934006
ICD10 via Orphanet28 D23.9
UMLS via Orphanet66 C0406803
UMLS65 C0406803

Summaries for Syringocystadenoma Papilliferum

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Wikipedia:68 Syringocystadenoma papilliferum (also known as \"Syringadenoma papilliferum\") is an apocrine tumor. more...

MalaCards based summary: Syringocystadenoma Papilliferum, also known as fistulous vegetative verrucous hydradenoma, is related to lymphoma and leukemia, and has symptoms including abnormal hair quantity, abnormal blistering of the skin and neoplasm of the skin. An important gene associated with Syringocystadenoma Papilliferum is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways are Negative regulation of MAPK pathway and MAPK Signaling: Oxidative Stress Pathway. Affiliated tissues include skin, prostate and t cells, and related mouse phenotypes are renal/urinary system and limbs/digits/tail.

Related Diseases for Syringocystadenoma Papilliferum

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Graphical network of the top 20 diseases related to Syringocystadenoma Papilliferum:



Diseases related to syringocystadenoma papilliferum

Symptoms for Syringocystadenoma Papilliferum

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Symptoms:

 51
  • follicular/erythematous/edematous papules/milium
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • hypotrichosis/atrichia/atrichiasis/scalp hairlessness
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • capillary hemangioma/nevus/naevus flammeus/port-wine stain
  • skin/cutaneous neoplasm/tumor/carcinoma/cancer (excluding melanoma)

HPO human phenotypes related to Syringocystadenoma Papilliferum:

id Description Frequency HPO Source Accession
1 abnormal hair quantity hallmark (90%) HP:0011362
2 abnormal blistering of the skin typical (50%) HP:0008066
3 neoplasm of the skin occasional (7.5%) HP:0008069

Drugs & Therapeutics for Syringocystadenoma Papilliferum

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Syringocystadenoma Papilliferum

Genetic Tests for Syringocystadenoma Papilliferum

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Anatomical Context for Syringocystadenoma Papilliferum

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MalaCards organs/tissues related to Syringocystadenoma Papilliferum:

33
Skin, Prostate, T cells, Heart, Endothelial, Liver, Thyroid

Animal Models for Syringocystadenoma Papilliferum or affiliated genes

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MGI Mouse Phenotypes related to Syringocystadenoma Papilliferum:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.4BRAF, KRAS, PORCN, SALL1
2MP:00053718.3KRAS, KRT5, PORCN, SALL1
3MP:00053828.2BRAF, KRAS, KRT5, PORCN
4MP:00053817.8BRAF, KRAS, KRT5, PORCN, SALL1
5MP:00053787.2AZGP1, BRAF, KRAS, KRT5, PORCN, SALL1

Publications for Syringocystadenoma Papilliferum

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Articles related to Syringocystadenoma Papilliferum:

(show top 50)    (show all 140)
idTitleAuthorsYear
1
Aniridia after blunt trauma and presumed wound dehiscence in a pseudophakic eye. (26840167)
2016
2
Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants: Consensus Communication. (26760846)
2016
3
Periostitis ossificans managed with endodontic treatment. (25909844)
2015
4
Primary hyperparathyroidism in pregnancy: a two-case report and literature review. (25893124)
2015
5
Fascin and EMMPRIN expression in primary mucinous tumors of ovary: a tissue microarray study. (25155376)
2014
6
A Fas-Associated via Death Domain Promoter Polymorphism (rs10898853, -16C/T) as a Risk Factor for Papillary Thyroid Cancer. (24434721)
2014
7
Curative effect study of pulsed dye laser in the treatment of 43 patients with hand infantile hemangioma. (24413474)
2014
8
CMT-associated mutations in glycyl- and tyrosyl-tRNA synthetases exhibit similar pattern of toxicity and share common genetic modifiers in Drosophila. (24807208)
2014
9
Transcatheter closure of a pulmonary arteriovenous malformation in a patient with hereditary hemorrhagic telangiectasia. (24928099)
2014
10
BB-UVA vs. NB-UVB in the treatment of vitiligo: a randomized controlled clinical study (single blinded). (24001379)
2013
11
Safety and impact on diagnostic accuracy of early analgesia in suspected acute appendicitis: a meta-analysis. (23973418)
2013
12
Acute disseminated encephalomyelitis. (23622336)
2013
13
Itga2b regulation at the onset of definitive hematopoiesis and commitment to differentiation. (22952660)
2012
14
Structure of factor H-binding protein B (FhbB) of the periopathogen, Treponema denticola: insights into progression of periodontal disease. (22371503)
2012
15
Pulmonary angiocentric lymphoma (lymphomatoid granulomatosis) in a donkey. (21571299)
2012
16
Disturbed emotion recognition in patients with narcissistic personality disorder. (22406389)
2012
17
Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptor. (21840393)
2011
18
Renal tubular acidosis due to Wilson's disease presenting as metabolic bone disease. (22688476)
2011
19
Swine influenza (H1N1) and acute appendicitis. (20633930)
2010
20
Goiter depicted in Byzantine artworks. (21112867)
2010
21
Orlistat for overweight subjects with nonalcoholic steatohepatitis. (19492425)
2009
22
Genetic and environmental contributors to cryptorchidism. (19550382)
2009
23
Correlation of DNA mismatch repair protein hMSH2 immunohistochemistry with p53 and apoptosis in cervical carcinoma. (17352217)
2007
24
Association of CHRM2 with IQ: converging evidence for a gene influencing intelligence. (17160701)
2007
25
Increased soluble E-cadherin in melanoma patients. (16685144)
2006
26
Notch signaling enhances nestin expression in gliomas. (17217625)
2006
27
Evidence for the presence of toll-like receptor 4 system in the human endometrium. (15509642)
2005
28
Long-term hormone replacement therapy does not cause increased platelet activation. (16169320)
2005
29
Diagnostic and prognostic value of heart-type fatty acid-binding protein (H-FABP), an early biochemical marker of myocardial injury]. (16435602)
2005
30
Pharmacoutilization of statin therapy after acute myocardial infarction. A real practice analysis based on administrative data. (15086141)
2004
31
Compartmentalization of visual centers in the Drosophila brain requires Slit and Robo proteins. (15525663)
2004
32
Medical treatment of nephrolithiasis. (12474645)
2002
33
Detection of Bacillus anthracis DNA by LightCycler PCR. (12149348)
2002
34
Effect of race on biochemical disease-free outcome in patients with prostate cancer treated with definitive radiation therapy in an equal-access health care system: radiation oncology report of the Department of Defense Center for Prostate Disease Research. (12409575)
2002
35
Human piebaldism: six novel mutations of the proto-oncogene KIT. (12204004)
2002
36
Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosis. (11972529)
2002
37
Warfarin resistance and enteral feedings: 2 case reports and a supporting in vitro study. (11552202)
2001
38
L-NAME-induced dispersion of melanosomes in melanophores activates PKC, MEK and ERK1. (11775057)
2001
39
Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2. (10799509)
2000
40
Angiotensin-converting enzyme (ACE) inhibition in the secondary prevention of vascular disease: the Heart Outcomes Prevention Evaluation (HOPE) Trial and its substudies. (11122766)
2000
41
Cutting edge: C-C chemokine receptor 6 is essential for arrest of a subset of memory T cells on activated dermal microvascular endothelial cells under physiologic flow conditions in vitro. (11120783)
2000
42
Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements. (10022872)
1999
43
X-linked mental retardation with variable stature, head circumference, and testicular volume linked to Xq12-q21. (10398233)
1999
44
Alpha interferon inhibits human herpesvirus 8 (HHV-8) reactivation in primary effusion lymphoma cells and reduces HHV-8 load in cultured peripheral blood mononuclear cells. (10196299)
1999
45
Effects of colestipol alone and in combination with simvastatin on apolipoprotein B metabolism. (8620338)
1996
46
Mediation of noradrenaline-induced contractions of rat aorta by the alpha 1B-adrenoceptor subtype. (7773533)
1995
47
Bovine angiotensin converting enzyme cDNA cloning and regulation. Increased expression during endothelial cell growth arrest. (1315639)
1992
48
Human insulin and hypoglycemia]. (2237055)
1990
49
Fibromuscular dysplasia of the extracranial carotid arteries. Case reports. (6695295)
1984
50

Variations for Syringocystadenoma Papilliferum

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Expression for genes affiliated with Syringocystadenoma Papilliferum

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Search GEO for disease gene expression data for Syringocystadenoma Papilliferum.

Pathways for genes affiliated with Syringocystadenoma Papilliferum

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GO Terms for genes affiliated with Syringocystadenoma Papilliferum

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Cellular components related to Syringocystadenoma Papilliferum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrionGO:00057399.1BRAF, KRAS, KRT5

Biological processes related to Syringocystadenoma Papilliferum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron apoptotic processGO:00435249.4BRAF, KRAS
2somatic stem cell population maintenanceGO:00350199.3BRAF, SALL1

Sources for Syringocystadenoma Papilliferum

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet