SCAP
MCID: SYR002
MIFTS: 41

Syringocystadenoma Papilliferum (SCAP) malady

Categories: Rare diseases, Skin diseases, Cancer diseases

Aliases & Classifications for Syringocystadenoma Papilliferum

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Sources:
11Disease Ontology, 13DISEASES, 31ICD10 via Orphanet, 45NCIt, 48NIH Rare Diseases, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Syringocystadenoma Papilliferum:

Name: Syringocystadenoma Papilliferum 11 48 54 13 68
Fistulous Vegetative Verrucous Hydradenoma 48 54
Naevus Syringocystadenomatosus Papilliferus 54
Syringadenoma Papilliferum 54
 
Papillary Syringadenoma 11
Papillary Hidradenoma 68
Scap 54

Characteristics:

Orphanet epidemiological data:

54
syringocystadenoma papilliferum:
Inheritance: Not applicable; Age of onset: Adolescent,Childhood,Infancy,Neonatal

Classifications:

Orphanet: 54 
Rare skin diseases


External Ids:

Disease Ontology11 DOID:5445
NCIt45 C4172
Orphanet54 ORPHA840
SNOMED-CT62 239121009, 8934006
UMLS via Orphanet69 C0406803
ICD10 via Orphanet31 D23.9

Summaries for Syringocystadenoma Papilliferum

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Wikipedia:71 Syringocystadenoma papilliferum (also known as \"Syringadenoma papilliferum\") is a benign apocrine... more...

MalaCards based summary: Syringocystadenoma Papilliferum, also known as fistulous vegetative verrucous hydradenoma, is related to sebaceous adenoma and adenoma, and has symptoms including Array, Array and Array. An important gene associated with Syringocystadenoma Papilliferum is DES (Desmin), and among its related pathways are Aurora B signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include skin, breast and lung, and related mouse phenotypes are Decreased viability and Decreased cell migration.

Related Diseases for Syringocystadenoma Papilliferum

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Diseases related to Syringocystadenoma Papilliferum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 202)
idRelated DiseaseScoreTop Affiliating Genes
1sebaceous adenoma29.9DES, MUC1, VIM
2adenoma10.5
3apocrine adenoma10.4
4basal cell carcinoma10.4
5glucosidase acid-1,4-alpha deficiency10.3DES, GFAP
6hidradenoma10.3
7invasive malignant thymoma10.2DES, MUC1
813q12.3 microdeletion syndrome10.2DES, VIM
9episodic ataxia10.2DES, MUC1
10polydactyly cleft lip palate psychomotor retardation10.2DES, MUC1
11inflammatory linear verrucous epidermal nevus10.2DES, VIM
12lymphomatous thyroiditis10.2DES, VIM
13intrahepatic bile duct cystadenoma10.2DES, S100B
14osteomyelitis10.2DES, VIM
15congenital myasthenic syndrome10.2DES, VIM
16malignant dermis tumor10.2DES, VIM
17adult endodermal sinus tumor10.2DES, VIM
18foix-alajouanine syndrome10.2DES, S100B
19pseudohermaphrodism anorectal anomalies10.2DES, MUC1
20biemond syndrome10.2DES, VIM
21liver angiosarcoma10.2DES, VIM
22intestinal obstruction10.2DES, VIM
23bronchial mucus gland adenoma10.2GFAP, S100B
24male urethral cancer10.2DES, VIM
25nephrogenic adenoma of urinary bladder10.2GFAP, VIM
26adenofibroma10.2GFAP, S100B
27adult brainstem gliosarcoma10.2GFAP, VIM
28lucey-driscoll syndrome10.2MUC1, S100B
29secondary pulmonary hemosiderosis10.2MUC1, S100B
30invasive mole10.2MUC1, S100B
31glomangioma10.2DES, VIM
32pemphigus vegetans10.2MUC1, S100B
33immunodeficiency due to a classical component pathway complement deficiency10.2MUC1, VIM
34piussan lenaerts mathieu syndrome10.2GFAP, S100B
35corneal intraepithelial neoplasm10.2MUC1, S100B
36bladder adenocarcinoma10.2MUC1, VIM
37calcific tendinitis10.2GFAP, VIM
38avian influenza10.2MUC1, VIM
39endocardium cancer10.2MUC1, S100B
40testicular granulosa cell tumor10.2MUC1, VIM
41auricular cancer10.2GFAP, S100B
42vulvar angiokeratoma10.2MUC1, VIM
43t-cell childhood lymphoblastic lymphoma10.2DES, VIM
44progeria10.2MUC1, VIM
45pediculus humanus corporis infestation10.2GFAP, S100B
46lupus - neurological sequelae10.2S100B, VIM
47childhood medulloblastoma10.2DES, GFAP
48benign schwannoma10.2S100B, VIM
49pilar sheath acanthoma10.2DES, VIM
50gestational trophoblastic neoplasm10.2MUC1, VIM

Graphical network of the top 20 diseases related to Syringocystadenoma Papilliferum:



Diseases related to syringocystadenoma papilliferum

Symptoms & Phenotypes for Syringocystadenoma Papilliferum

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Human phenotypes related to Syringocystadenoma Papilliferum:

 54 64
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 subcutaneous nodule64 54 Very frequent (99-80%) HP:0001482
2 sparse scalp hair64 54 Very frequent (99-80%) HP:0002209
3 abnormal blistering of the skin64 54 Frequent (79-30%) HP:0008066
4 nevus sebaceous64 54 Occasional (29-5%) HP:0010815
5 papule64 54 Very frequent (99-80%) HP:0200034

GenomeRNAi Phenotypes related to Syringocystadenoma Papilliferum according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00381-A-19.3BRAF, KRAS, MUC1
2GR00055-A-18.9BRAF, KRAS, MUC1, VIM

MGI Mouse Phenotypes related to Syringocystadenoma Papilliferum according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.0BRAF, DES, GFAP, KRAS, S100B, VIM
2MP:00053697.7BRAF, DES, GFAP, KRAS, VIM

Drugs & Therapeutics for Syringocystadenoma Papilliferum

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Syringocystadenoma Papilliferum

Genetic Tests for Syringocystadenoma Papilliferum

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Anatomical Context for Syringocystadenoma Papilliferum

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MalaCards organs/tissues related to Syringocystadenoma Papilliferum:

36
Skin, Breast, Lung

Publications for Syringocystadenoma Papilliferum

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Articles related to Syringocystadenoma Papilliferum:

(show top 50)    (show all 147)
idTitleAuthorsYear
1
Syringocystadenoma Papilliferum of the Scalp Arising from a Nevus Sebaceous. (27761094)
2016
2
Syringocystadenoma papilliferum of the external auditory canal. Case report and literature review. (27658577)
2016
3
Syringocystadenoma papilliferum with multiple lung metastases and long survival. (27837643)
2016
4
Tubulopapillary Cystic Adenoma With Apocrine Differentiation: A Unifying Concept for Syringocystadenoma Papilliferum, Apocrine Gland Cyst, and Tubular Papillary Adenoma. (28033156)
2016
5
Somatic V600E BRAF Mutation in Linear and Sporadic Syringocystadenoma Papilliferum. (25950823)
2015
6
Tricholemmoma, sebaceoma, syringocystadenoma papilliferum, basal cell carcinoma, trichilemmal cyst arising within a nevus sebaceous. (26224239)
2015
7
Fifteen year natural history of lower eyelid syringocystadenoma papilliferum in a young girl. (26097022)
2015
8
Syringocystadenoma papilliferum in an unusual location. (26734876)
2015
9
Somatic BRAF c.1799T>A p.V600E Mosaicism syndrome characterized by a linear syringocystadenoma papilliferum, anaplastic astrocytoma, and ocular abnormalities. (26360803)
2015
10
A case of syringocystadenoma papilliferum of eyelid with literature review. (26265653)
2015
11
Multiple pigmented trichoblastomas, sebaceous carcinoma and syringocystadenoma papilliferum arising within a nevus sebaceous. (25906325)
2015
12
Activating mutations in the RAS/mitogen-activated protein kinase signaling pathway in sporadic trichoblastoma and syringocystadenoma papilliferum. (25532942)
2015
13
Basal Cell Carcinoma and Syringocystadenoma Papilliferum Arising in Nevus Sebaceous on Face-A Rare Entity. (26677302)
2015
14
Trichoblastoma, syringocystadenoma papilliferum, desmoplastic trichilemmoma, and tumor of the follicular infundibulum with signet-ring cells, all arising in nevus sebaceus. (25761672)
2015
15
Eruptive Syringocystadenoma Papilliferum, Keratoacanthoma, and Verruca Vulgaris in a Keratinocytic Epidermal Nevus on the Leg. (26790513)
2015
16
Cytological diagnosis of syringocystadenoma papilliferum a rare adnexal tumor. (26229253)
2015
17
Syringocystadenoma papilliferum of the male nipple. (26269194)
2015
18
Syringocystadenoma papilliferum arising on naevus sebaceus: A 6-year-old child case described with dermoscopic features. (25900640)
2015
19
Syringocystadenoma papilliferum developing over hyperkeratosis of the nipple in a pregnant woman. (24629369)
2014
20
Syringocystadenoma papilliferum of the upper lip. (25364565)
2014
21
Linear syringocystadenoma papilliferum on female breast: a rare appendageal tumour on an uncommon location. (25756479)
2014
22
Syringocystadenoma papilliferum: an unusual presentation. (24995228)
2014
23
A case of syringocystadenoma papilliferum on lower leg: a rare location. (24082194)
2013
24
Syringocystadenoma papilliferum in the right lower abdomen: a case report and review of literature. (23569386)
2013
25
Syringocystadenoma papilliferum of the bony external auditory canal: a rare tumor in a rare location. (23762705)
2013
26
Syringocystadenoma papilliferum of the scalp in an adult male - a case report. (23730665)
2013
27
Linear syringocystadenoma papilliferum: a case report with review of literature. (24082219)
2013
28
Syringocystadenoma papilliferum on the dorsum of the foot. (23621843)
2013
29
Agminated syringocystadenoma papilliferum: a new clinical presentation of a rare benign adnexal neoplasm. (24021448)
2013
30
Follicular hybrid cyst with isthmic-catagen, pilomatrical, and syringocystadenoma papilliferum components. (22699865)
2013
31
Syringocystadenoma papilliferum arising on the scrotum. (22612442)
2013
32
Giant linear syringocystadenoma papilliferum of the back. (22199089)
2012
33
Adult-onset linear syringocystadenoma papilliferum over the inguinal fold: a case report with emphasis on mast cell staining pattern. (23217957)
2012
34
Carcino-sarcoma in a case of syringocystadenoma papilliferum: a rare entity. (24765470)
2012
35
Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary-like glands: report of a case and review of the literature. (22262361)
2012
36
Squamous cell carcinoma, syringocystadenoma papilliferum and apocrine adenoma arising in a nevus sebaceus of Jadassohn. (21393932)
2011
37
Linear syringocystadenoma papilliferum: an unusual location. (21276059)
2011
38
Syringocystadenoma papilliferum on the male nipple. (21914158)
2011
39
Linear syringocystadenoma papilliferum: an uncommon event with a favorable prognosis. (21906485)
2011
40
Dermoscopic aspects of syringocystadenoma papilliferum associated with nevus sebaceus. (22281917)
2011
41
Syringocystadenoma papilliferum. (22372162)
2011
42
Syringocystadenoma Papilliferum in Co-existence with Tubular Apocrine Adenoma on the Calf. (22148043)
2011
43
Syringocystadenoma papilliferum of the back combined with a tubular apocrine adenoma. (22148038)
2011
44
Basal cell carcinoma, syringocystadenoma papilliferum, trichilemmoma, and sebaceoma arising within a nevus sebaceus associated with pigmented nevi. (22093024)
2011
45
Lipomatous apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. (21854651)
2011
46
What is your diagnosis? Syringocystadenoma papilliferum. (22017063)
2011
47
Report of 3 histopathologically documented cases of syringocystadenoma papilliferum involving the eyelid. (21784220)
2011
48
Syringocystadenoma papilliferum: Unusual location. (21696687)
2011
49
Syringocystadenoma papilliferum in an unusual location beyond the head and neck region: a case report and review of literature. (21062598)
2010
50
A case of zonal syringocystadenoma papilliferum of the axilla mimicking verruca vulgaris. (20098083)
2010

Variations for Syringocystadenoma Papilliferum

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Expression for genes affiliated with Syringocystadenoma Papilliferum

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Search GEO for disease gene expression data for Syringocystadenoma Papilliferum.

Pathways for genes affiliated with Syringocystadenoma Papilliferum

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GO Terms for genes affiliated with Syringocystadenoma Papilliferum

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Cellular components related to Syringocystadenoma Papilliferum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.7DES, GFAP
2intermediate filamentGO:00058829.6DES, GFAP, VIM
3cytoplasmGO:00057377.3BRAF, DES, GFAP, KRAS, MUC1, S100B

Biological processes related to Syringocystadenoma Papilliferum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament organizationGO:004510910.2DES, VIM
2muscle filament slidingGO:003004910.2DES, VIM
3long-term synaptic potentiationGO:006029110.0BRAF, S100B
4visual learningGO:00085429.0BRAF, KRAS
5positive regulation of gene expressionGO:00106289.0BRAF, KRAS, VIM

Molecular functions related to Syringocystadenoma Papilliferum according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.2DES, GFAP, VIM
2identical protein bindingGO:00428028.6BRAF, DES, GFAP, S100B, VIM

Sources for Syringocystadenoma Papilliferum

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet