MCID: SYR003
MIFTS: 37

Syringoma malady

Categories: Rare diseases, Cancer diseases, Skin diseases

Aliases & Classifications for Syringoma

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Aliases & Descriptions for Syringoma:

Name: Syringoma 10 45 47 12 36 65
 
Syringoma Nos 10

Classifications:



External Ids:

Disease Ontology10 DOID:2065
MeSH36 D018252
NCIt42 C3761
UMLS65 C0206673

Summaries for Syringoma

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NIH Rare Diseases:45 Syringomas are firm yellowish, translucent, or skin colored papules that are often found on the face, particularly around the eyes. they may occur suddenly in crops or multiples. they arise from the sweat ducts. they usually cause no symptoms. they are not associated with underlying abnormality. they are found more commonly in caucasians, and in females at puberty or near middle-age. last updated: 8/6/2009

MalaCards based summary: Syringoma, also known as syringoma nos, is related to vulvar syringoma and malignant syringoma. An important gene associated with Syringoma is S100B (S100 Calcium Binding Protein B), and among its related pathways are Aurora B signaling and Striated Muscle Contraction. Affiliated tissues include skin, breast and eye.

Wikipedia:68 Syringomas are harmless eccrine sweat duct tumors, typically found clustered on eyelids, although they... more...

Related Diseases for Syringoma

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Diseases in the Syringoma family:

Malignant Syringoma

Diseases related to Syringoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 143)
idRelated DiseaseScoreTop Affiliating Genes
1vulvar syringoma12.1
2malignant syringoma12.1
3chondroid syringoma of the vulva11.9
4syringomas natal teeth oligodontia11.9
5malignant acrospiroma10.9
6meningothelial meningioma10.6MUC1, S100B
7situs inversus10.6ESR1, MUC1
8breast granular cell tumor10.5ESR1, MUC1
9benign deep fibrous histiocytoma10.5DES, S100B
10atrophoderma vermiculata10.5DES, S100B
11familial syringomyelia10.5DES, MUC1
12benign peritoneal mesothelioma10.5ESR1, MUC1
13pancreatic invasive mucinous cystadenocarcinoma10.5ESR1, MUC1
14nerve compression syndrome10.5DES, ESR1
15pediatric mesenchymal chondrosarcoma10.5DES, MUC1
16malignant ovarian brenner tumor10.4MUC1, VIM
17absence of fingerprints congenital milia10.4MUC1, VIM
18proliferative fasciitis10.4DES, S100B
19vulvar clear cell hidradenocarcinoma10.4KRT1, MUC1
20thymus lipoma10.4DES, ESR1
21cutaneous ganglioneuroma10.4S100B, VIM
22ovarian mucinous cystadenocarcinoma10.4MUC1, VIM
23myelomeningocele10.4DES, MUC1
24parachordoma10.4MUC1, VIM
25headache10.4GFAP, S100B
26esophageal lipoma10.4DES, VIM
27gingival hypertrophy10.4DES, VIM
28congenital fibrosis of the extraocular muscles10.4DES, VIM
29pinheiro freire-maia miranda syndrome10.4GFAP, S100B
30papillary carcinoma10.4MUC1, VIM
31spindle cell variant squamous cell breast carcinoma10.3DES, VIM
32adult malignant schwannoma10.3GFAP, MUC1
33uveal diseases10.3DES, ESR1
34benign multicystic peritoneal mesothelioma10.3DES, VIM
35ependymoblastoma10.3GFAP, S100B
36adult mesoblastic nephroma10.3DES, VIM
37iris spindle cell melanoma10.3DES, VIM
38clear cell ependymoma10.3GFAP, S100B
39uterine corpus adenocarcinofibroma10.3DES, VIM
40ulcer of lower limbs10.3GFAP, S100B
41lymphoplasmacyte-rich meningioma10.3MUC1, VIM
42asthenopia10.2ESR1, MUC1
43lung leiomyosarcoma10.2DES, VIM
44brain ischemia10.2GFAP, S100B
45head and neck carcinoma10.2ESR1, GFAP
46familial short qt syndrome10.2MUC1, VIM
47small intestine leiomyosarcoma10.2ESR1, GFAP
4846xy sex reversal 510.2DES, VIM
49childhood cerebellar neoplasm10.2GFAP, VIM
50childhood cerebral astrocytoma10.2GFAP, S100B

Graphical network of the top 20 diseases related to Syringoma:



Diseases related to syringoma

Symptoms for Syringoma

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Drugs & Therapeutics for Syringoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Trial of Radiotherapy and Panitumumab in Salivary Gland MalignanciesWithdrawnNCT00984217Phase 2

Search NIH Clinical Center for Syringoma


Cochrane evidence based reviews: syringoma

Genetic Tests for Syringoma

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Anatomical Context for Syringoma

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MalaCards organs/tissues related to Syringoma:

33
Skin, Breast, Eye, Lung, Brain, T cells, Salivary gland

Animal Models for Syringoma or affiliated genes

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Publications for Syringoma

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Articles related to Syringoma:

(show top 50)    (show all 350)
idTitleAuthorsYear
1
Chondroid syringoma with extensive bone formation: a case report and review of the literature. (25478357)
2014
2
Chondroid syringoma with extensive osseous differentiation: a rare finding. (24943789)
2014
3
Chondroid syringoma of the medial canthus. (24744935)
2014
4
A curious serendipitous finding: Spitz naevus combined with a syringoma. (22671019)
2013
5
Penile syringoma: reports and review of patients with syringoma located on the penis. (23882308)
2013
6
Giant chondroid syringoma of the eyelid. (23931483)
2013
7
Facial localization of malignant chondroid syringoma: a rare case report. (23476847)
2013
8
Eruptive milium-like syringoma showing eccrine duct origin of milia. (22150478)
2012
9
Mohs micrographic surgery for recurrent chondroid syringoma of the eyebrow. (22309155)
2012
10
Commentary: treatment of syringoma using an ablative 10,600-nm carbon dioxide fractional laser. (21481062)
2011
11
Chondroid syringoma of the scalp: case report and discussion of clinical features, histopathology, and treatment. (21500172)
2011
12
Malignant chondroid syringoma: report of a case with lymph node metastasis 12 years after local excision. (21971270)
2011
13
Eruptive widespread papular eruption on the abdomen: a quiz. Clear cell syringoma, eruptive variant. (21264456)
2011
14
Autosomal dominant multiple syringomas linked to chromosome 16q22. (20132207)
2010
15
Eruptive syringoma associated with hyperthyroidism. (20527152)
2010
16
Milia with calcium deposits on the palms and soles in a patient with multiple syringoma. (20653855)
2010
17
Autoimmune acrosyringitis with ductal cysts: reclassification of case of eruptive syringoma. (19522848)
2009
18
Chondroid syringoma: a rare tumor of orofacial region. (19633639)
2009
19
Eruptive syringoma developed over a waxing skin area. (18645310)
2008
20
Syringoma-like eccrine sweat duct proliferation induced by radiation. (16469082)
2006
21
Periorbital syringoma: a pilot study of the efficacy of low-voltage electrocoagulation. (17034373)
2006
22
A rare case of chondroid syringoma arising from the lower eyelid with ectropion. (17051093)
2006
23
Elevated levels of serum carcinoembryonic antigen in a patient with eruptive syringoma. (16112373)
2005
24
Eruptive syringoma in four Black South African children. (15550160)
2004
25
Chondroid syringoma. Cytokeratin 20 immunolocalization of Merkel cells and reappraisal of apocrine folliculo-sebaceous differentiation. (15335266)
2004
26
Chondroid syringoma of the upper lip: a case report. (16027488)
2004
27
Cutaneous benign mixed tumor (chondroid syringoma) of the eyelid: clinical presentation and management. (15083078)
2004
28
Brooke-Spiegler syndrome associated with cylindroma, trichoepithelioma, spiradenoma, and syringoma. (14739501)
2004
29
Multiple syringomas in an unusual distribution. (14673269)
2003
30
Chondroid syringoma. A case report. (12038117)
2002
31
High-dose-rate endobronchial brachytherapy in endobronchial metastatic malignant chondroid syringoma. (11464090)
2001
32
Vulvar syringoma causing pruritus and carcinophobia: treatment by argon laser. (11360416)
1999
33
Eruptive syringoma. (20921761)
1998
34
Chondroid syringoma: an immunohistochemical study using antibodies to Ca 15-3, KA-93, Ca 19-9, CD44 and BM-1. (9001983)
1996
35
Milium-like syringoma in the perianal region. (8534946)
1995
36
Chondroid syringoma. A rare occurrence in the hallux. (8394420)
1993
37
Fine needle aspiration cytology of chondroid syringoma and syringocystadenoma papilliferum. A report of two cases. (8392255)
1993
38
Eruptive syringoma. (8388104)
1993
39
Subclinical syringoma coexisting with nevocellular nevus on the vulva. (8478501)
1993
40
Generalised eruptive syringoma--a papular dermatosis. (1965678)
1990
41
Syringoma presenting as milia. (3819065)
1987
42
Multiple penile papules. Syringoma. (3662576)
1987
43
Syringoma of the ankle. (6715599)
1984
44
Syringoma of the forehead. (6840942)
1983
45
Acral syringoma: electron microscopic studies on its origin. (6175141)
1982
46
Chondroid syringoma (mixed tumour) of radius. (6266947)
1981
47
Ultrastructure of chondroid syringoma: role of the myoepithelial cell in the development of the mixed tumor of the skin and soft tissues. (222430)
1979
48
Metastasising chondroid syringoma. (4352760)
1973
49
50

Variations for Syringoma

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Cosmic variations for Syringoma:

7
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1COSM214343CYLDskin,face,adnexal tumour,trichoepithelioma4

Expression for genes affiliated with Syringoma

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Search GEO for disease gene expression data for Syringoma.

Pathways for genes affiliated with Syringoma

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GO Terms for genes affiliated with Syringoma

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Cellular components related to Syringoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.3DES, VIM
2keratin filamentGO:00450959.2KRT1, KRT14

Biological processes related to Syringoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament-based processGO:00451039.5GFAP, VIM
2epithelial cell differentiationGO:00308559.3KRT14, MUC1

Sources for Syringoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet