MCID: SYR003
MIFTS: 36

Syringoma malady

Categories: Rare diseases, Cancer diseases, Skin diseases

Aliases & Classifications for Syringoma

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Aliases & Descriptions for Syringoma:

Name: Syringoma 10 45 47 12 36 65
 
Syringoma Nos 10

Classifications:



External Ids:

Disease Ontology10 DOID:2065
MeSH36 D018252
NCIt42 C3761
UMLS65 C0206673

Summaries for Syringoma

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NIH Rare Diseases:45 Syringomas are firm yellowish, translucent, or skin colored papules that are often found on the face, particularly around the eyes. they may occur suddenly in crops or multiples. they arise from the sweat ducts. they usually cause no symptoms. they are not associated with underlying abnormality. they are found more commonly in caucasians, and in females at puberty or near middle-age. last updated: 8/6/2009

MalaCards based summary: Syringoma, also known as syringoma nos, is related to papillary carcinoma and large cell neuroendocrine carcinoma. An important gene associated with Syringoma is S100B (S100 Calcium Binding Protein B), and among its related pathways are Aurora B signaling and Striated Muscle Contraction. Affiliated tissues include skin, eye and bone.

Wikipedia:68 Syringomas are harmless eccrine sweat duct tumors, typically found clustered on eyelids, although they... more...

Related Diseases for Syringoma

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Diseases in the Syringoma family:

Malignant Syringoma

Diseases related to Syringoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 351)
idRelated DiseaseScoreTop Affiliating Genes
1papillary carcinoma30.2MUC1, VIM
2large cell neuroendocrine carcinoma29.9DES, VIM
3estrogen-receptor positive breast cancer29.6ESR1, KRT14, MUC1
4melanoma29.5DES, MUC1, S100B, VIM
5vulvar syringoma12.4
6malignant syringoma12.3
7chondroid syringoma of the vulva12.3
8syringomas natal teeth oligodontia12.3
9malignant acrospiroma11.3
10meningothelial meningioma10.4MUC1, S100B
11situs inversus10.4ESR1, MUC1
12breast granular cell tumor10.3ESR1, MUC1
13benign deep fibrous histiocytoma10.3DES, S100B
14atrophoderma vermiculata10.3DES, S100B
15familial syringomyelia10.3DES, MUC1
16benign peritoneal mesothelioma10.3ESR1, MUC1
17pancreatic invasive mucinous cystadenocarcinoma10.3ESR1, MUC1
18nerve compression syndrome10.3DES, ESR1
19pediatric mesenchymal chondrosarcoma10.3DES, MUC1
20malignant ovarian brenner tumor10.3MUC1, VIM
21absence of fingerprints congenital milia10.3MUC1, VIM
22proliferative fasciitis10.3DES, S100B
23vulvar clear cell hidradenocarcinoma10.3KRT1, MUC1
24thymus lipoma10.3DES, ESR1
25cutaneous ganglioneuroma10.3S100B, VIM
26ovarian mucinous cystadenocarcinoma10.3MUC1, VIM
27myelomeningocele10.3DES, MUC1
28parachordoma10.3MUC1, VIM
29headache10.2GFAP, S100B
30esophageal lipoma10.2DES, VIM
31gingival hypertrophy10.2DES, VIM
32congenital fibrosis of the extraocular muscles10.2DES, VIM
33pinheiro freire-maia miranda syndrome10.2GFAP, S100B
34spindle cell variant squamous cell breast carcinoma10.2DES, VIM
35adult malignant schwannoma10.2GFAP, MUC1
36uveal diseases10.2DES, ESR1
37benign multicystic peritoneal mesothelioma10.2DES, VIM
38ependymoblastoma10.2GFAP, S100B
39breast cancer10.2
40thyroiditis10.2
41endotheliitis10.2
42adult mesoblastic nephroma10.2DES, VIM
43iris spindle cell melanoma10.2DES, VIM
44clear cell ependymoma10.2GFAP, S100B
45uterine corpus adenocarcinofibroma10.2DES, VIM
46ulcer of lower limbs10.2GFAP, S100B
47lymphoplasmacyte-rich meningioma10.2MUC1, VIM
48hepatitis10.2
49lymphoma10.2
50tuberculosis10.2

Graphical network of the top 20 diseases related to Syringoma:



Diseases related to syringoma

Symptoms for Syringoma

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Drugs & Therapeutics for Syringoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Trial of Radiotherapy and Panitumumab in Salivary Gland MalignanciesWithdrawnNCT00984217Phase 2

Search NIH Clinical Center for Syringoma


Cochrane evidence based reviews: syringoma

Genetic Tests for Syringoma

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Anatomical Context for Syringoma

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MalaCards organs/tissues related to Syringoma:

33
Skin, Eye, Bone, Salivary gland, Lung, T cells, Endothelial

Animal Models for Syringoma or affiliated genes

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Publications for Syringoma

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Articles related to Syringoma:

(show top 50)    (show all 339)
idTitleAuthorsYear
1
A pre-eclampsia-associated Epstein-Barr virus antibody cross-reacts with placental GPR50. (27181993)
2016
2
Reactivation of coccidioidomycosis: a prosthetic joint infection in Spain. (26638217)
2016
3
Fascin and EMMPRIN expression in primary mucinous tumors of ovary: a tissue microarray study. (25155376)
2014
4
The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis. (24666267)
2014
5
Peliosis hepatis: a complicating finding in a case of biliary colic. (24072833)
2013
6
Study on TRPV1-mediated mechanism for the hypersecretion of mucus in respiratory inflammation. (22935106)
2013
7
A case of parosteal osteosarcoma with a rare complication of myositis ossificans. (23194024)
2012
8
Effect of inflammatory response on in vivo competition between two chlamydial variants in the guinea pig model of inclusion conjunctivitis. (22144478)
2012
9
Investigation of autoantibody profiles for cerebrospinal fluid biomarker discovery in patients with relapsing-remitting multiple sclerosis. (22177943)
2012
10
Periodontal disease and type 2 diabetes mellitus: is the HMGB1-RAGE axis the missing link? (22800803)
2012
11
Possible unilateral ultraviolet keratoconjunctivitis during an expedition-length desert race. (20591383)
2010
12
Kappa opioid receptor contributes to EGF-stimulated neurite extension in development. (20133770)
2010
13
Strength training does not influence serum brain-derived neurotrophic factor. (20467874)
2010
14
TRPC6 channel protects retinal ganglion cells in a rat model of retinal ischemia/reperfusion-induced cell death. (20554625)
2010
15
Serenoa Repens: Does It have Any Role in the Management of Androgenetic Alopecia? (20300369)
2009
16
Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype. (19422052)
2009
17
Involvement of the chromatin-remodeling factor BRG1/SMARCA4 in human cancer. (18437052)
2008
18
Type 1 von Willebrand disease. (17635702)
2007
19
CD163 expression confers susceptibility to porcine reproductive and respiratory syndrome viruses. (17494075)
2007
20
Dofetilide: a new class III antiarrhythmic agent. (17187453)
2007
21
Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle. (17360977)
2007
22
Thrombin generation in vascular tissue. (16409451)
2006
23
Primary amenorrhea. Varied etiology. (16155669)
2005
24
Association of Gly972Arg variant of insulin receptor substrate-1 with metabolic features in women with polycystic ovary syndrome. (16084882)
2005
25
Gene therapy]. (15773357)
2005
26
The protective effect of delta-aminolevulinic acid dehydratase 1-2 and 2-2 isozymes against blood lead with higher hematologic parameters. (15064157)
2004
27
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease. (15276015)
2004
28
Bone mineral density and bone metabolism are not related to leptin in hemodialyzed and peritoneally dialyzed uremic patients. (16538212)
2004
29
Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells. (14699076)
2004
30
Enhanced glucose-dependent glucagon-like peptide-1 and insulin secretion in Crohn patients with terminal ileum disease is unrelated to disease activity or ileal resection. (15370686)
2004
31
Protein-c deficiency in a patient with Legg-CalvAc-Perthes disease and recurrent deep vein thrombosis. (12046918)
2002
32
Osteochondroma of the C5 lamina with cord compression: case report and review of the literature. (10806510)
2000
33
Molecular behavior of mutant Lewis enzymes in vivo. (10089211)
1999
34
Angiotensin II signal transduction in vascular smooth muscle: pathways activated by specific tyrosine kinases. (9892142)
1999
35
Calcineurin enhances MEF2 DNA binding activity in calcium-dependent survival of cerebellar granule neurons. (10521511)
1999
36
cDNA characterization and chromosome mapping of the human GAS2 gene. (9521882)
1998
37
Complex regulation of transferrin receptors during erythropoietin-induced differentiation of J2E erythroid cells--elevated transcription and mRNA stabilisation produce only a modest rise in protein content. (9363756)
1997
38
Influence of different techniques of breath holding on the measurement of cerebrovascular reserve in carotid artery disease. (8650728)
1996
39
Characterization of acute promyelocytic leukemia cases with PML-RAR alpha break/fusion sites in PML exon 6: identification of a subgroup with decreased in vitro responsiveness to all-trans retinoic acid. (7632962)
1995
40
The effect of feed intake and growth hormone-releasing factor on lactating dairy cows. (7540632)
1995
41
The role of Chlamydia pneumoniae in severe acute tonsillitis. (8163914)
1994
42
Isomeric selectivity at dopamine D3 receptors. (8223909)
1993
43
Gliofibroma: immunohistochemical analysis. (1557951)
1992
44
Increased plasma pyridoxal-5'-phosphate levels before and after pyridoxine loading in carriers of perinatal/infantile hypophosphatasia. (2079838)
1990
45
Spino-cerebellar degeneration with polyneuropathy associated with ceroid lipofuscinosis in one family. (3422677)
1988
46
Noninvasive method to assess cor pulmonale in patients with chronic obstructive pulmonary disease. (2954775)
1987
47
Sporotrichosis in India: first authentic case report from the north-western region and a critical literature review. (3746583)
1986
48
Vulvovaginitis in Children. (20781430)
1938
49
50

Variations for Syringoma

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Cosmic variations for Syringoma:

7
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1COSM214343CYLDskin,face,adnexal tumour,trichoepithelioma1

Expression for genes affiliated with Syringoma

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Search GEO for disease gene expression data for Syringoma.

Pathways for genes affiliated with Syringoma

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GO Terms for genes affiliated with Syringoma

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Cellular components related to Syringoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.3DES, VIM
2keratin filamentGO:00450959.2KRT1, KRT14

Biological processes related to Syringoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament-based processGO:00451039.5GFAP, VIM
2epithelial cell differentiationGO:00308559.3KRT14, MUC1

Sources for Syringoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet