Systemic Lupus Erythematosus 16 malady
Categories: Genetic diseases, Rare diseases, Immune diseases, Skin diseases, Bone diseases
Aliases & Descriptions for Systemic Lupus Erythematosus 16:
systemic lupus erythematosus 16:
Inheritance: autosomal recessive inheritance
Global: Genetic diseases, Rare diseases
Anatomical: Immune diseases, Skin diseases, Bone diseases
UniProtKB/Swiss-Prot:67 Systemic lupus erythematosus 16: A rare autosomal recessive form of systemic lupus erythematosus with childhood onset, characterized by high frequency of anti-neutrophil cytoplasmic antibodies and lupus nephritis. Systemic lupus erythematosus is a chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
MalaCards based summary: Systemic Lupus Erythematosus 16, also known as sleb16, is related to systemic lupus erythematosus, and has symptoms including nephritisand systemic lupus erythematosus. An important gene associated with Systemic Lupus Erythematosus 16 is DNASE1L3 (Deoxyribonuclease I Like 3). Affiliated tissues include bone, skin and bone marrow.
Description from OMIM:49 614420
Diseases in the Lupus Erythematosus family:
Diseases related to Systemic Lupus Erythematosus 16 via text searches within MalaCards or GeneCards Suite gene sharing:
Drugs for Systemic Lupus Erythematosus 16 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show top 50) (show all 92)
Interventional clinical trials:(show all 24)
Search NIH Clinical Center for Systemic Lupus Erythematosus 16
MalaCards organs/tissues related to Systemic Lupus Erythematosus 16:33
Bone, Skin, Bone marrow, Kidney, Neutrophil, Endothelial
Search GEO for disease gene expression data for Systemic Lupus Erythematosus 16.
28ICD10 via Orphanet
37MESH via Orphanet
50OMIM via Orphanet
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
66UMLS via Orphanet