MCID: SYS061
MIFTS: 22

Systemic Lupus Erythematosus 16 malady

Genetic diseases, Bone diseases, Rare diseases, Immune diseases, Skin diseases categories

Summaries for Systemic Lupus Erythematosus 16

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MalaCards based summary: Systemic Lupus Erythematosus 16, also known as autosomal recessive systemic lupus erythematosus, is related to systemic lupus erythematosus and lupus erythematosus, and has symptoms including autosomal recessive inheritanceand nephritis. An important gene associated with Systemic Lupus Erythematosus 16 is DNASE1L3 (deoxyribonuclease I-like 3). The compound calcium have been mentioned in the context of this disorder. Affiliated tissues include bone.

Description from OMIM:46 614420

Aliases & Classifications for Systemic Lupus Erythematosus 16

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Sources:
46OMIM, 61UMLS, 48Orphanet, 27ICD10 via Orphanet
See all sources

Systemic Lupus Erythematosus 16, Aliases & Descriptions:

Name: Systemic Lupus Erythematosus 16 46 61
Autosomal Recessive Systemic Lupus Erythematosus 48
Familial Systemic Lupus Erythematosus 48
 
Autosomal Recessive Sle 48
Familial Sle 48


Classifications:



Characteristics (Orphanet epidemiological data):

48
autosomal recessive systemic lupus erythematosus:
Inheritance: Autosomal recessive; Prevalence: <1/1000000; Age of onset: Childhood


External Ids:

OMIM46 614420
ICD10 via Orphanet27 M32.8

Related Diseases for Systemic Lupus Erythematosus 16

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Graphical network of diseases related to Systemic Lupus Erythematosus 16:



Diseases related to systemic lupus erythematosus 16

Symptoms for Systemic Lupus Erythematosus 16

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Symptoms by clinical synopsis from OMIM:

614420

Clinical features from OMIM:

614420

HPO human phenotypes related to Systemic Lupus Erythematosus 16:

id Description Frequency HPO Source Accession
1 autosomal recessive inheritance HP:0000007
2 nephritis HP:0000123

Drugs & Therapeutics for Systemic Lupus Erythematosus 16

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Drug clinical trials:

Search ClinicalTrials for Systemic Lupus Erythematosus 16

Search NIH Clinical Center for Systemic Lupus Erythematosus 16

Genetic Tests for Systemic Lupus Erythematosus 16

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Anatomical Context for Systemic Lupus Erythematosus 16

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MalaCards organs/tissues related to Systemic Lupus Erythematosus 16:

32
Bone

Animal Models for Systemic Lupus Erythematosus 16 or affiliated genes

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Publications for Systemic Lupus Erythematosus 16

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Variations for Systemic Lupus Erythematosus 16

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Clinvar genetic disease variations for Systemic Lupus Erythematosus 16:

7
id Gene Name Type Significance SNP ID Assembly Location
1DNASE1L3DNASE1L3, 1-BP DEL, 643TdeletionPathogenic

Expression for genes affiliated with Systemic Lupus Erythematosus 16

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Expression patterns in normal tissues for genes affiliated with Systemic Lupus Erythematosus 16

Search GEO for disease gene expression data for Systemic Lupus Erythematosus 16.

Pathways for genes affiliated with Systemic Lupus Erythematosus 16

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Compounds for genes affiliated with Systemic Lupus Erythematosus 16

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Sources:
44Novoseek, 50PharmGKB, 25HMDB, 12DrugBank
See all sources

Compounds related to Systemic Lupus Erythematosus 16 according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium44 50 25 1212.1DNASE1L3, PRKCD

GO Terms for genes affiliated with Systemic Lupus Erythematosus 16

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Products for genes affiliated with Systemic Lupus Erythematosus 16

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Systemic Lupus Erythematosus 16

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet