MCID: SYS061
MIFTS: 22

Systemic Lupus Erythematosus 16 malady

Genetic diseases, Bone diseases, Rare diseases, Immune diseases, Skin diseases categories
Download this MalaCard

Summaries for Systemic Lupus Erythematosus 16

About this section


Fully expand this MalaCard
MalaCards based summary: Systemic Lupus Erythematosus 16, also known as autosomal recessive systemic lupus erythematosus, is related to systemic lupus erythematosus and lupus erythematosus, and has symptoms including An important gene associated with Systemic Lupus Erythematosus 16 is DNASE1L3 (deoxyribonuclease I-like 3). The compound calcium have been mentioned in the context of this disorder. Affiliated tissues include bone.

Description from OMIM:46 614420

Aliases & Classifications for Systemic Lupus Erythematosus 16

About this section
Sources:
46OMIM, 62UMLS, 48Orphanet, 26ICD10 via Orphanet
See all sources

Systemic Lupus Erythematosus 16, Aliases & Descriptions:

Name: Systemic Lupus Erythematosus 16 46 62
Autosomal Recessive Systemic Lupus Erythematosus 48
Familial Systemic Lupus Erythematosus 48
 
Autosomal Recessive Sle 48
Familial Sle 48


Classifications:



Characteristics (Orphanet epidemiological data):

48
autosomal recessive systemic lupus erythematosus:
Inheritance: Autosomal recessive; Prevalence: <1/1000000; Age of onset: Childhood


External Ids:

OMIM46 614420
ICD10 via Orphanet26 M32.8

Related Diseases for Systemic Lupus Erythematosus 16

About this section

Graphical network of diseases related to Systemic Lupus Erythematosus 16:



Diseases related to systemic lupus erythematosus 16

Symptoms for Systemic Lupus Erythematosus 16

About this section

Symptoms by clinical synopsis from OMIM:

614420

Clinical features from OMIM:

614420

HPO human phenotypes related to Systemic Lupus Erythematosus 16:

id Description Frequency HPO Source Accession
1 autosomal recessive inheritance HP:0000007
2 nephritis HP:0000123

Drugs & Therapeutics for Systemic Lupus Erythematosus 16

About this section

Drug clinical trials:

Search ClinicalTrials for Systemic Lupus Erythematosus 16

Search NIH Clinical Center for Systemic Lupus Erythematosus 16

Genetic Tests for Systemic Lupus Erythematosus 16

About this section

Anatomical Context for Systemic Lupus Erythematosus 16

About this section

MalaCards organs/tissues related to Systemic Lupus Erythematosus 16:

32
Bone

Animal Models for Systemic Lupus Erythematosus 16 or affiliated genes

About this section

Publications for Systemic Lupus Erythematosus 16

About this section

Variations for Systemic Lupus Erythematosus 16

About this section

Clinvar genetic disease variations for Systemic Lupus Erythematosus 16:

6
id Gene Name Type Significance SNP ID Assembly Location
1DNASE1L3DNASE1L3, 1-BP DEL, 643TdeletionPathogenic

Expression for genes affiliated with Systemic Lupus Erythematosus 16

About this section
Expression patterns in normal tissues for genes affiliated with Systemic Lupus Erythematosus 16

Search GEO for disease gene expression data for Systemic Lupus Erythematosus 16.

Pathways for genes affiliated with Systemic Lupus Erythematosus 16

About this section

Compounds for genes affiliated with Systemic Lupus Erythematosus 16

About this section
Sources:
44Novoseek, 50PharmGKB, 24HMDB, 11DrugBank
See all sources

Compounds related to Systemic Lupus Erythematosus 16 according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium44 50 24 1112.1DNASE1L3, PRKCD

GO Terms for genes affiliated with Systemic Lupus Erythematosus 16

About this section

Products for genes affiliated with Systemic Lupus Erythematosus 16

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Systemic Lupus Erythematosus 16

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet