MCID: TCL012
MIFTS: 25

T-Cell/histiocyte Rich Large B Cell Lymphoma malady

Blood diseases, Cancer diseases, Immune diseases categories

Summaries for T-Cell/histiocyte Rich Large B Cell Lymphoma

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32MalaCards
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MalaCards: T-Cell/histiocyte Rich Large B Cell Lymphoma, also known as t-cell rich/histiocyte-rich large b-cell lymphoma, is related to hodgkin's lymphoma and bone lymphoma. An important gene associated with T-Cell/histiocyte Rich Large B Cell Lymphoma is VSIG4 (V-set and immunoglobulin domain containing 4), and among its related pathways are Senescence and Autophagy and Development PDGF signaling via STATs and NF-kB. The compounds agarose and staurosporin have been mentioned in the context of this disorder. Affiliated tissues include b cells and t cells.

Aliases & Classifications for T-Cell/histiocyte Rich Large B Cell Lymphoma

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48Orphanet, 60UMLS, 57SNOMED-CT via Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Blood diseases, Immune diseases


Aliases & Descriptions:

t-cell/histiocyte rich large b cell lymphoma 48
t-cell rich/histiocyte-rich large b-cell lymphoma 60
thrlbcl 48


External Ids:

SNOMED-CT via Orphanet57 450959001
ICD10 via Orphanet26 C83.3

Related Diseases for T-Cell/histiocyte Rich Large B Cell Lymphoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to T-Cell/histiocyte Rich Large B Cell Lymphoma:



Diseases related to t-cell/histiocyte rich large b cell lymphoma

Clinical Features for T-Cell/histiocyte Rich Large B Cell Lymphoma

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Drugs & Therapeutics for T-Cell/histiocyte Rich Large B Cell Lymphoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for T-Cell/histiocyte Rich Large B Cell Lymphoma

Drug clinical trials:

Search ClinicalTrials for T-Cell/histiocyte Rich Large B Cell Lymphoma

Search NIH Clinical Center for T-Cell/histiocyte Rich Large B Cell Lymphoma

Search CenterWatch for T-Cell/histiocyte Rich Large B Cell Lymphoma

Genetic Tests for T-Cell/histiocyte Rich Large B Cell Lymphoma

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Anatomical Context for T-Cell/histiocyte Rich Large B Cell Lymphoma

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32MalaCards
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MalaCards organs/tissues related to T-Cell/histiocyte Rich Large B Cell Lymphoma:

32
B cells, T cells

Animal Models for T-Cell/histiocyte Rich Large B Cell Lymphoma or affiliated genes

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Publications for T-Cell/histiocyte Rich Large B Cell Lymphoma

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Genetic Variations for T-Cell/histiocyte Rich Large B Cell Lymphoma

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Expression for genes affiliated with T-Cell/histiocyte Rich Large B Cell Lymphoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with T-Cell/histiocyte Rich Large B Cell Lymphoma

Search GEO for disease gene expression data for T-Cell/histiocyte Rich Large B Cell Lymphoma.

Pathways for genes affiliated with T-Cell/histiocyte Rich Large B Cell Lymphoma

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37NCBI BioSystems Database, 29KEGG, 51QIAGEN
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Pathways related to T-Cell/histiocyte Rich Large B Cell Lymphoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.0BCL2, IFNG
2
Development PDGF signaling via STATs and NF-kB
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9.0BCL2, IFNG
39.0IFNG, BCL2
4
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9.0BCL2, IFNG
59.0BCL2, IFNG
69.0BCL2, IFNG

Compounds for genes affiliated with T-Cell/histiocyte Rich Large B Cell Lymphoma

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44Novoseek, 49PharmGKB, 11DrugBank
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Compounds related to T-Cell/histiocyte Rich Large B Cell Lymphoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1agarose449.3BCL2, IGH
2staurosporin449.2BCL2, IFNG
3triptolide449.1BCL2, IFNG
4suberoylanilide hydroxamic acid449.1BCL2, IFNG
5pdtc449.0IFNG, BCL2
6carboplatin44 49 1110.9BCL2, IFNG
7lactacystin448.7BCL2, IFNG

GO Terms for genes affiliated with T-Cell/histiocyte Rich Large B Cell Lymphoma

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16Gene Ontology
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Biological processes related to T-Cell/histiocyte Rich Large B Cell Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1defense response to virusGO:0516079.0BCL2, IFNG
2humoral immune responseGO:0069598.7BCL2, IFNG

Products for genes affiliated with T-Cell/histiocyte Rich Large B Cell Lymphoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for T-Cell/histiocyte Rich Large B Cell Lymphoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet