MCID: TKY002
MIFTS: 60

Takayasu Arteritis malady

Categories: Rare diseases, Cardiovascular diseases, Nephrological diseases, Bone diseases

Aliases & Classifications for Takayasu Arteritis

About this section
Sources:
50OMIM, 11Disease Ontology, 46NIH Rare Diseases, 13DISEASES, 52Orphanet, 37MeSH, 66UMLS, 28ICD10, 30ICD9CM, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Takayasu Arteritis:

Name: Takayasu Arteritis 50 11 46 52 37 66
Aortic Arch Syndromes 37 66
Takayasu's Arteritis 11 13
Aortic Arch Syndrome 11 46
Idiopathic Aortitis 11 66
Young Female Arteritis 46
 
Aortic Arch Arteritis 11
Aortic Arches Defect 46
Takayasu's Disease 11
Pulseless Disease 46
Takayasu Disease 46
Ta 46

Characteristics:

Orphanet epidemiological data:

52
takayasu arteritis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe),<1/1000000 (United Kingdom),1-9/100000 (Japan),1-9/1000000 (Sweden),1-9/1000000 (United Kingdom); Age of onset: Adolescent,Adult; Age of death: adult

Classifications:



External Ids:

OMIM50 207600
Disease Ontology11 DOID:2508
ICD1028 M31.4
ICD9CM30 446.7
Orphanet52 ORPHA3287
ICD10 via Orphanet29 M31.4
MESH via Orphanet38 D013625
UMLS via Orphanet67 C0039263

Summaries for Takayasu Arteritis

About this section
NIH Rare Diseases:46 Takayasu arteritis is a condition that causes inflammation of the main blood vessel that carries blood from the heart to the rest of the body (aorta) and its associated branched blood vessels. as a result of the inflammation, the blood vessel walls become thick and make it difficult for blood to flow. over time, impaired blood flow causes damage to the heart and various other organs of the body.  although the cause remains unknown, takayasu arteritis appears to be an autoimmune condition, in which cells that fight infection and disease are wrongly targeted against the body's own tissues. last updated: 11/3/2013

MalaCards based summary: Takayasu Arteritis, also known as aortic arch syndromes, is related to common variable immunodeficiency and renovascular hypertension, and has symptoms including hyperhidrosis, weight loss and aneurysm. An important gene associated with Takayasu Arteritis is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways are Legionellosis and Pertussis. The drug alprostadil has been mentioned in the context of this disorder. Affiliated tissues include heart, t cells and skin, and related mouse phenotypes are respiratory system and digestive/alimentary.

Disease Ontology:11 A syndrome that involves inflammation of the aorta that carries blood from the heart to the rest of the body.

Description from OMIM:50 207600

Related Diseases for Takayasu Arteritis

About this section

Diseases related to Takayasu Arteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 353)
idRelated DiseaseScoreTop Affiliating Genes
1common variable immunodeficiency31.1HLA-B, HLA-DRB1, TNF
2renovascular hypertension30.8CD40LG, HLA-DRB1, IL2, TNF
3pyoderma gangrenosum30.3IL2, IL6, TNF
4myocardial infarction27.9CRP, IL6, MMP3, MMP9, PON1, THBD
5systemic lupus erythematosus27.2CD40LG, CRP, HLA-DPB1, HLA-DRB1, IL2, IL6
6atypical coarctation of aorta11.2
7isotretinoin embryopathy-like syndrome11.2
8cervical aortic arch11.1
9rhizomelic dysplasia, scoliosis, and retinitis pigmentosa10.9MMP3, MMP9
10linitis plastica10.8IL2, TNF
11hernia of ovary and fallopian tube10.8HLA-B, HLA-DRB1, TNF
12branch retinal artery occlusion10.8HLA-A, HLA-B
13lymphocytic colitis10.8HLA-DRB1, IL6, TNF
14mastocytosis cutaneous with short stature conductive hearing loss and microtia10.8HLA-DRB1, IL6, TNF
15corneal intraepithelial neoplasm10.8HLA-B, IL6, TNF
16aneurysm of sinus of valsalva10.8CRP, IL6
17panner disease10.8CRP, IL6, TNF
18keloids10.8IL6, MMP3, TNF
19maligant granulosa cell tumor of ovary10.7IL2, IL6, TNF
20vitreoretinochoroidopathy dominant10.7HLA-B, HLA-DRB1, IL2
21islet cell tumor10.7CRP, IL6, TNF
22splenic manifestation of prolymphocytic leukemia10.7IL2, IL6, TNF
23proximal symphalangism10.7HLA-DRB1, MMP9, TNF
24paraneoplastic polyneuropathy10.7CRP, IL6, TNF
25progressive locomotor ataxia10.7HLA-A, HLA-B, HLA-DRB1
26mechanical lagophthalmos10.7CRP, IL6, TNF
27oral candidiasis10.7CRP, IL6, TNF
28large cell carcinoma with rhabdoid phenotype10.7CRP, MMP9, TNF
29human herpesvirus 810.7HLA-A, HLA-B, IL6
30burn scar10.7IL6, MMP9, TNF
31cervix erosion10.7CRP, IL6, TNF
32c1 inhibitor deficiency10.7CRP, IL6, TNF
33mitochondrial encephalomyopathy10.7HLA-A, HLA-B, HLA-DRB1
34nervous system cancer10.7IL6, MMP9, TNF
35hypercementosis10.7HLA-A, HLA-B, HLA-DRB1
36vertebral artery occlusion10.7IL6, MMP3, MMP9
37foster-kennedy syndrome10.7HLA-A, HLA-B, HLA-DRB1
38bardet-biedl syndrome 810.7CRP, IL6, TNF
39serous labyrinthitis10.7IL2, IL6, TNF
40benign peritoneal mesothelioma10.7CRP, IL6, TNF
41alopecia10.7CRP, IL6, TNF
42spinal stenosis10.7IL6, MMP9, TNF
43aseptic osteitis10.7HLA-A, HLA-B, HLA-DRB1
44periodic paralyses10.7IL2, IL6, PON1
45cutaneous porphyria10.7CRP, IL6, TNF
46midline interhemispheric variant of holoprosencephaly10.7CRP, IL2, IL6
47spondylolysis10.7CRP, IL6, TNF
48anaerobic pneumonia10.7IL6, PON1, TNF
49iridocyclitis10.7HLA-DRB1, IL2, IL6
50common cold10.7IL2, IL6, TNF

Graphical network of the top 20 diseases related to Takayasu Arteritis:



Diseases related to takayasu arteritis

Symptoms for Takayasu Arteritis

About this section

Symptoms by clinical synopsis from OMIM:

207600

Clinical features from OMIM:

207600

Symptoms:

 52 (show all 38)
  • retinopathy
  • hypertension
  • hyperhidrosis
  • seizures
  • muscle weakness
  • arthritis
  • subcutaneous nodule
  • hypertrophic cardiomyopathy
  • abnormality of the aortic valve
  • abnormality of the heart valves
  • myocardial infarction
  • weight loss
  • anemia
  • fever
  • anorexia
  • migraine
  • pulmonary hypertension
  • hemoptysis
  • neurological speech impairment
  • aneurysm
  • vasculitis
  • cerebral ischemia
  • abnormal pattern of respiration
  • arthralgia
  • myalgia
  • abnormality of the endocardium
  • reduced consciousness/confusion
  • dilatation of the ascending aorta
  • gastrointestinal infarctions
  • fatigue
  • increased inflammatory response
  • inflammatory abnormality of the eye
  • arterial stenosis
  • amaurosis fugax
  • hypertensive crisis
  • chest pain
  • gangrene
  • skin ulcer

HPO human phenotypes related to Takayasu Arteritis:

(show all 40)
id Description Frequency HPO Source Accession
1 hyperhidrosis hallmark (90%) HP:0000975
2 weight loss hallmark (90%) HP:0001824
3 aneurysm hallmark (90%) HP:0002617
4 vasculitis hallmark (90%) HP:0002633
5 abnormality of temperature regulation hallmark (90%) HP:0004370
6 hypertensive crisis hallmark (90%) HP:0100735
7 abnormality of the aorta hallmark (90%) HP:0001679
8 visual impairment typical (50%) HP:0000505
9 seizures typical (50%) HP:0001250
10 muscle weakness typical (50%) HP:0001324
11 arthritis typical (50%) HP:0001369
12 hypertrophic cardiomyopathy typical (50%) HP:0001639
13 abnormality of the aortic valve typical (50%) HP:0001646
14 coronary artery disease typical (50%) HP:0001677
15 anemia typical (50%) HP:0001903
16 anorexia typical (50%) HP:0002039
17 migraine typical (50%) HP:0002076
18 pulmonary hypertension typical (50%) HP:0002092
19 abnormal pattern of respiration typical (50%) HP:0002793
20 myalgia typical (50%) HP:0003326
21 dilatation of the ascending aorta typical (50%) HP:0005111
22 inflammatory abnormality of the eye typical (50%) HP:0100533
23 chest pain typical (50%) HP:0100749
24 gangrene typical (50%) HP:0100758
25 skin ulcer typical (50%) HP:0200042
26 respiratory insufficiency typical (50%) HP:0002093
27 apnea typical (50%) HP:0002104
28 retinopathy occasional (7.5%) HP:0000488
29 hemoptysis occasional (7.5%) HP:0002105
30 neurological speech impairment occasional (7.5%) HP:0002167
31 cerebral ischemia occasional (7.5%) HP:0002637
32 arthralgia occasional (7.5%) HP:0002829
33 abnormality of the endocardium occasional (7.5%) HP:0004306
34 reduced consciousness/confusion occasional (7.5%) HP:0004372
35 gastrointestinal infarctions occasional (7.5%) HP:0005244
36 amaurosis fugax occasional (7.5%) HP:0100576
37 asthma occasional (7.5%) HP:0002099
38 recurrent respiratory infections occasional (7.5%) HP:0002205
39 feeding difficulties in infancy occasional (7.5%) HP:0008872
40 arteritis HP:0012089

UMLS symptoms related to Takayasu Arteritis:


vasculitic rash

Drugs & Therapeutics for Takayasu Arteritis

About this section

Drugs for Takayasu Arteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AbataceptPhase 2188332348-12-610237
Synonyms:
CTLA4-Ig
 
CTLA4-IgG4m
CTLA4Ig
CTLA4IgG4m
2
PrednisonePhase 2131853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
3glucocorticoidsPhase 24756
4INTERLEUKIN-2Phase 2537
5
infliximabPhase 2364170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
6
AldesleukinPhase 239185898-30-2, 110942-02-4
Synonyms:
125-L-serine-2-133-interleukin 2 (human reduced)
 
Interleukin-2 aldesleukin
Interleukin-2(2-133),125-ser
Recombinant interleukin-2 human
7Epoetin alfaPhase 1, Phase 2638113427-24-0
8
Miconazole357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
9
Prednisolone111850-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
10
Methylprednisolone111883-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
11lenograstim1178
12Alkylating Agents4573
13
Cyclophosphamide275650-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
14PREDNISOLONE ACETATE1118
15
GlucosamineNutraceutical1653416-24-8439213
Synonyms:
(+)-2-amino-2-deoxy-D-glucopyranose
(2R,3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
(2S,5R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol
14257-69-3
2-Amino-2-deoxy-D-Glucose
2-Amino-2-deoxy-D-glucopyranose
2-Amino-2-deoxy-D-glucose
2-Amino-2-deoxy-beta-D-glucopyranose
2-Amino-2-deoxyglucose
2-Aminoglucose
2-Deoxy-2-amino-D-glucose
2-Deoxy-2-aminoglucose
2-amino-2-deoxy-D-glucopyranose
2-amino-2-deoxyglucose
2351-15-7
28905-10-4
2B4D44B2-D5AC-4DA4-9BE6-A4AE9574E4A6
3416-24-8
4-04-00-02017 (Beilstein Handbook Reference)
58-87-7
58267-75-7
6490-70-6
880765-44-6
90-77-7
911653-84-4
AC1L2D1C
AC1L96WB
AC1L9B8P
AC1Q4UBH
BRN 1724602
BSPBio_002086
C00329
C08349
CHEBI:28393
CHEBI:47977
CHEMBL234432
CID18897
CID439213
CID441477
CPD0-1193
Chitosamine
Cosamin
D-(+)-Glucosamine
 
D-Glucosamine
D-glucosamine
D04334
DB01296
DivK1c_000261
EINECS 222-311-2
GCS
Glucosamina
Glucosamina [INN-Spanish]
Glucosamine (USAN/INN)
Glucosamine [USAN:INN]
Glucosaminum
Glucosaminum [INN-Latin]
HMS500N03
HSDB 7469
IDI1_000261
InChI=1/C6H13NO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1,7H2/t2-,3-,4-,5-,6-/m1/s1
KBio1_000261
KBio2_001311
KBio2_003879
KBio2_006447
KBio3_001306
KBioGR_000970
KBioSS_001311
LS-71671
MolPort-002-507-091
MolPort-003-944-937
NCGC00164421-01
NCGC00178826-01
NINDS_000261
SPBio_000477
STK801823
Spectrum2_000519
Spectrum3_000443
Spectrum4_000565
Spectrum5_000756
Spectrum_000831
Viartril-S
beta-D-Glucosamine
bmse000247
chitosamine
glucosamine
nchembio.189-comp4
nchembio.2007.41-comp7
nchembio.412-comp5
partially N-deacetylated poly-beta-1,6-N-acetyl-D-glucosamine
16KavaNutraceutical1379000-38-8

Interventional clinical trials:

(show all 27)
idNameStatusNCT IDPhase
1Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein LevelsTerminatedNCT00578578Phase 4
2Efficacy and Tolerance of Tocilizumab In Takayasu ArteritisNot yet recruitingNCT02101333Phase 3
3Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's ArteritisCompletedNCT00556439Phase 2
4Clinical Study of Anti-tumor Necrosis Factor Therapy in Patients With Takayasu ArteritisRecruitingNCT02457585Phase 2
5Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory DiseasesRecruitingNCT01988506Phase 2
6Erythropoetin Neuroprotection for Neonatal Cardiac SurgeryActive, not recruitingNCT00513240Phase 1, Phase 2
7Impact and Utility of PET Versus Clinical Score for the Assessment of Inflammatory Activity in Takayasu ArteritisCompletedNCT01532167
8Carotid Artery Neovascularization in Takayasu's and Giant Cell ArteritisCompletedNCT01795456
9Educational Needs of Patients With Systemic VasculitisCompletedNCT02190929
10Reproductive Health in Men and Women With VasculitisCompletedNCT02176070
11Vasculitis Illness Perception (VIP) StudyCompletedNCT02190916
12Impact of Vasculitis on Employment and IncomeCompletedNCT02476292
13Magnetic Resonance Angiography vs Ultrasonography in Systemic Large vEssel vasculitiSCompletedNCT02042092
14Cerebral Perfusion During Neonatal Cardiac SurgeryCompletedNCT01032876
15Determining Disease Activity Biomarkers in Individuals With Takayasu's ArteritisRecruitingNCT00315471
16Use of MRI and PET for Assessing Disease Activity in Takayasu's ArteritisRecruitingNCT00744952
17Exercise in Sjogren, Myositis and Takayasu's ArteritisRecruitingNCT01501019
18American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic VasculitisRecruitingNCT01066208
19Pediatric Vasculitis InitiativeRecruitingNCT02006134
20Vasculitis Pregnancy RegistryRecruitingNCT02593565
21Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory DiseasesRecruitingNCT02925351
22One-Time DNA Study for VasculitisRecruitingNCT01241305
23Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune DiseasesActive, not recruitingNCT00006055
24Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence StudyActive, not recruitingNCT01663129
25Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart SyndromeActive, not recruitingNCT01135485
26VCRC Patient Contact Registry Patient-Reported Data Validation StudyEnrolling by invitationNCT02190942
27Aortic Arch ReconstructionTerminatedNCT00277940

Search NIH Clinical Center for Takayasu Arteritis

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: takayasu arteritis

Genetic Tests for Takayasu Arteritis

About this section

Anatomical Context for Takayasu Arteritis

About this section

MalaCards organs/tissues related to Takayasu Arteritis:

34
Heart, T cells, Skin, Eye, Bone, Thyroid

Animal Models for Takayasu Arteritis or affiliated genes

About this section

MGI Mouse Phenotypes related to Takayasu Arteritis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053887.9IL12B, IL2, IL6, MMP9, PTPN22, SELE
2MP:00053817.6IL12B, IL2, IL6, MMP9, PTPN22, THBD
3MP:00053846.4CD40LG, IL2, IL6, MMP9, PON1, PTPN22
4MP:00053976.2CD40LG, IL12B, IL2, IL6, MMP3, MMP9
5MP:00053876.1CD40LG, CRP, IL12B, IL2, IL6, MMP3
6MP:00053855.9CD40LG, CRP, IL2, IL6, MMP9, PON1
7MP:00053765.3CD40LG, CRP, IL12B, IL2, IL6, MMP3

Publications for Takayasu Arteritis

About this section

Articles related to Takayasu Arteritis:

(show top 50)    (show all 128)
idTitleAuthorsYear
1
(18)F]-Sodium fluoride uptake in Takayasu arteritis. (27506703)
2016
2
Early Assessment of Treatment Response in Takayasu Arteritis: An 18FDG PET Procedure. (27280904)
2016
3
Effects of immunosuppressive and biological agents on refractory Takayasu arteritis patients unresponsive to glucocorticoid treatment. (27567177)
2016
4
Takayasu arteritis presenting with malignant hypertension; a rare manifestation of a rare disease: a case report and review of the literature. (27216226)
2016
5
Absence of mycobacterial DNA in peripheral blood and artery specimens in patients with Takayasu arteritis. (27604701)
2016
6
Inflammatory disease of the aorta: Patterns and classification of giant cell aortitis, Takayasu arteritis, and nonsyndromic aortitis. (25218529)
2014
7
An unusual case of Coats disease associated with Takayasu arteritis. (25448151)
2014
8
Clinical Features and Radiological Findings in Large Vessel Vasculitis: Are Takayasu Arteritis and Giant Cell Arteritis 2 Different Diseases or a Single Entity? (25399386)
2014
9
Dilated cardiomyopathy being the presenting manifestation of takayasu arteritis and treated with renal angioplasty. (25324267)
2014
10
Incidentally diagnosed Takayasu arteritis on thyroid ultrasonography showing prominent collateral vessels of thyroidal arteries and common carotid artery occlusion. (25038813)
2014
11
A case of infantile Takayasu arteritis with a p.D382E NOD2 mutation: an unusual phenotype of Blau syndrome/early-onset sarcoidosis? (22821420)
2013
12
Tonic pupil, anterior ischemic optic neuropathy in a teenager with Takayasu arteritis. (24314433)
2013
13
Clinical and vascular features of Takayasu arteritis at the time of ischemic stroke. (24435029)
2013
14
Takayasu arteritis combined with congenital supravalvular aortic stenosis. (23886030)
2013
15
Treatment of cerebral aneurysms associated with Takayasu arteritis. (23422136)
2013
16
Role of FDG-PET/CT in diagnosis of aortitis caused by Takayasu arteritis and IgG4-related systemic disease. (23933571)
2013
17
Critical ostial left main and right coronary artery stenosis secondary to takayasu arteritis in a young female simulating pulmonary embolism at presentation. (23388240)
2013
18
Renovascular hypertension--is it fibromuscular dysplasia or Takayasu arteritis. (22453736)
2013
19
New human leukocyte antigen risk allele in Japanese patients with Takayasu arteritis. (22664757)
2012
20
Cardiac manifestations in a young man with Takayasu arteritis associated with antiphospholipid syndrome. (23393717)
2012
21
Rescue treatment with tocilizumab for Takayasu arteritis resistant to TNF-I+ blockers. (22410150)
2012
22
Bronchiectasis and hoarseness of voice in takayasu arteritis: a rare presentation. (22905814)
2012
23
Takayasu arteritis presenting with internal carotid artery dissection. (22456469)
2012
24
Ghrelin and adipokines as circulating markers of disease activity in patients with Takayasu arteritis. (23259466)
2012
25
Surgical bypass vs endovascular treatment for patients with supra-aortic arterial occlusive disease due to Takayasu arteritis. (22119246)
2012
26
A novel approach to the treatment of recurrent non-atherosclerotic carotid stenosis in a patient with Takayasu arteritis. (22121053)
2012
27
Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, Takayasu arteritis) and polymyalgia rheumatica. (22674883)
2012
28
Immunoglobulin G4-related disease with lymphoplasmacytic aortitis mimicking Takayasu arteritis. (22089986)
2011
29
The role of tumor necrosis factor-I+ promoter genetic variation in Takayasu arteritis susceptibility and medical treatment. (21965637)
2011
30
Takayasu arteritis initially mimicking infective endocarditis. (22084654)
2011
31
EULAR/PRINTO/PRES criteria for Henoch-SchAPnlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria. (20413568)
2010
32
Left main coronary artery aneurysm in a patient with Takayasu arteritis: parellel images from aortography, computed tomography, and magnetic resonance tomography. (20857459)
2010
33
Pericardial effusion as primary manifestation of Takayasu arteritis. (19193462)
2010
34
Rapid progression of aortic regurgitation with thoracic aortic aneurysm due to Takayasu arteritis associated with ulcerative colitis. (20519817)
2010
35
A rare cause of renovascular hypertension: Takayasu arteritis with only renal artery involvement. (19462284)
2009
36
A case of Takayasu arteritis complicated by Castleman's disease. (18825473)
2008
37
Comparison distribution of HLA-B alleles in mexican patients with takayasu arteritis and tuberculosis. (17462513)
2007
38
Carotidynia in Takayasu arteritis. (17216692)
2007
39
A case of Takayasu arteritis complicated with glomerulonephropathy mimicking membranoproliferative glomerulonephritis: a case report and review of the literature. (16830159)
2006
40
Takayasu arteritis with high titre of antiphospholipid antibodies and MTHFR Polymorphism. (16133896)
2005
41
Reactive thrombocytosis: an early manifestation of Takayasu arteritis. (16357775)
2005
42
A case of Takayasu arteritis complicated with glomerulonephropathy mimicking membranoproliferative glomerulonephritis. (15801074)
2004
43
Malignant hypertension as a presenting symptom of Takayasu arteritis. (12583535)
2003
44
Stroke related to carotid artery dissection in a young patient with Takayasu arteritis, systemic lupus erythematosus and antiphospholipid antibody syndrome. (11810014)
2002
45
Takayasu arteritis and renovascular hypertension. (11269685)
2001
46
Association of HLA-DRB1*1602 and DRB1*1001 with Takayasu arteritis in Colombian mestizos as markers of Amerindian ancestry. (10980348)
2000
47
Interleukin-6 and RANTES in Takayasu arteritis: a guide for therapeutic decisions? (10393681)
1999
48
Takayasu arteritis presenting as amaurosis fugax in a man. (9517701)
1998
49
Successful pregnancy and long-term follow-up (12 years) in a patient with Takayasu arteritis and renovascular hypertension as a first clinical sign. (9247789)
1997
50
Comprehensive analysis of HLA genes in Takayasu arteritis in Japan. (9119528)
1996

Variations for Takayasu Arteritis

About this section

Expression for genes affiliated with Takayasu Arteritis

About this section
Search GEO for disease gene expression data for Takayasu Arteritis.

Pathways for genes affiliated with Takayasu Arteritis

About this section

Pathways related to Takayasu Arteritis according to GeneCards Suite gene sharing:

(show all 39)
idSuper pathwaysScoreTop Affiliating Genes
19.8IL12B, IL6, TNF
29.8IL12B, IL6, TNF
39.8HLA-A, HLA-B, MICA
49.7IL6, MMP9, TNF
59.6IL6, MMP9, THBD
69.5HLA-A, HLA-B, HLA-DPB1, HLA-DRB1
79.5HLA-A, HLA-B, HLA-DPB1, HLA-DRB1
89.5MMP3, MMP9, SELE
99.5IL12B, IL2, IL6
10
Show member pathways
9.4HLA-A, IL2, TNF
119.4IL2, IL6, SELE
129.3HLA-DPB1, HLA-DRB1, IL12B, IL6, TNF
139.3CD40LG, IL6, TNF, VCAM1
14
Show member pathways
9.3CD40LG, IL2, TNF
15
Show member pathways
9.2CD40LG, HLA-DPB1, HLA-DRB1, IL12B, TNF
16
Show member pathways
9.2IL12B, IL2, IL6, TNF
17
Show member pathways
9.2HLA-A, HLA-DRB1, IL12B, IL2
18
Show member pathways
9.2HLA-DPB1, HLA-DRB1, IL12B, IL2
199.2IL12B, IL6, SELE, TNF, VCAM1
209.2HLA-DPB1, HLA-DRB1, IL6, MMP3, TNF
21
Show member pathways
9.1HLA-A, HLA-B, HLA-DPB1, HLA-DRB1, VCAM1
229.1CD40LG, HLA-A, HLA-B, MICA, VCAM1
239.1IL2, IL6, THBD, TNF
249.1IL2, IL6, MMP9, TNF
259.0CD40LG, IL6, SELE, TNF, VCAM1
269.0IL6, SELE, THBD, TNF, VCAM1
279.0IL2, IL6, TNF, VCAM1
289.0HLA-DRB1, IL12B, IL2, IL6, TNF
29
Show member pathways
9.0HLA-A, HLA-B, IL2, MICA, TNF
308.9CD40LG, IL12B, IL2, IL6, TNF
31
Show member pathways
8.8HLA-A, HLA-B, IL12B, IL2, IL6, TNF
32
Show member pathways
8.6CD40LG, HLA-DPB1, HLA-DRB1, IL12B, IL2, TNF
338.6IL6, MMP3, MMP9, SELE, TNF, VCAM1
348.5CD40LG, HLA-A, HLA-B, HLA-DPB1, HLA-DRB1, SELE
35
Show member pathways
8.3HLA-A, HLA-B, HLA-DPB1, HLA-DRB1, IL12B, IL2
368.1CD40LG, IL2, PTPN22, TNF, VCAM1
378.1HLA-A, HLA-B, HLA-DPB1, HLA-DRB1, IL2, IL6
38
Show member pathways
7.8CD40LG, HLA-A, HLA-B, HLA-DPB1, HLA-DRB1, IL12B
39
Show member pathways
6.6CD40LG, CRP, HLA-A, HLA-B, HLA-DPB1, HLA-DRB1

GO Terms for genes affiliated with Takayasu Arteritis

About this section

Cellular components related to Takayasu Arteritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class I protein complexGO:004261210.7HLA-A, HLA-B
2integral component of lumenal side of endoplasmic reticulum membraneGO:007155610.2HLA-A, HLA-B, HLA-DPB1, HLA-DRB1
3ER to Golgi transport vesicle membraneGO:001250710.2HLA-A, HLA-B, HLA-DPB1, HLA-DRB1
4external side of plasma membraneGO:00098979.7CD40LG, IL6, TNF, VCAM1
5cell surfaceGO:00099868.0CD40LG, HLA-A, HLA-B, HLA-DPB1, HLA-DRB1, MICA
6extracellular regionGO:00055767.0CRP, IL12B, IL2, IL6, MMP3, MMP9
7extracellular spaceGO:00056156.3CD40LG, CRP, IL12B, IL2, IL6, MICA

Biological processes related to Takayasu Arteritis according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.7IL6, TNF
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:000248010.7HLA-A, HLA-B
3regulation of immunoglobulin secretionGO:005102310.5CD40LG, TNF
4positive regulation of tissue remodelingGO:003410510.4IL12B, IL2
5negative regulation of lipid storageGO:001088810.3CRP, IL6, TNF
6positive regulation of immunoglobulin secretionGO:005102410.3IL2, IL6
7antigen processing and presentationGO:001988210.3HLA-A, HLA-B, MICA
8leukocyte tethering or rollingGO:005090110.2SELE, TNF, VCAM1
9leukocyte cell-cell adhesionGO:000715910.0CD40LG, SELE, VCAM1
10positive regulation of interferon-gamma productionGO:00327299.7HLA-DPB1, IL12B, IL2, TNF
11defense response to Gram-positive bacteriumGO:00508309.7CRP, IL6, TNF
12interferon-gamma-mediated signaling pathwayGO:00603339.7HLA-A, HLA-B, HLA-DPB1, HLA-DRB1, VCAM1
13inflammatory responseGO:00069549.5CD40LG, CRP, IL6, SELE, TNF
14regulation of immune responseGO:00507769.4CD40LG, HLA-A, HLA-B, MICA, VCAM1
15T cell costimulationGO:00312959.4CD40LG, HLA-DPB1, HLA-DRB1
16leukocyte migrationGO:00509009.3MMP9, SELE, THBD, TNF
17extracellular matrix organizationGO:00301989.0MMP9, TNF, VCAM1, VWF
18positive regulation of T cell proliferationGO:00421028.5CD40LG, HLA-DPB1, IL12B, IL2, IL6, VCAM1
19response to lipopolysaccharideGO:00324968.5IL6, PTPN22, SELE, THBD, VCAM1

Molecular functions related to Takayasu Arteritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1beta-2-microglobulin bindingGO:003088110.4HLA-A, MICA
2peptide antigen bindingGO:00426059.5HLA-A, HLA-B, HLA-DPB1, HLA-DRB1
3cytokine activityGO:00051258.6CD40LG, IL12B, IL2, IL6, TNF

Sources for Takayasu Arteritis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet