MCID: TNY001
MIFTS: 28

Tanycytic Ependymoma malady

Category: Cancer diseases

Aliases & Classifications for Tanycytic Ependymoma

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Aliases & Descriptions for Tanycytic Ependymoma:

Name: Tanycytic Ependymoma 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:5504
SNOMED-CT60 397378002, 57706008
NCIt43 C6903

Summaries for Tanycytic Ependymoma

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MalaCards based summary: Tanycytic Ependymoma is related to ependymoma and grubben de cock borghgraef syndrome. An important gene associated with Tanycytic Ependymoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways are Deactivation of the beta-catenin transactivating complex and Neuroscience. Affiliated tissues include spinal cord, and related mouse phenotypes are neoplasm and muscle.

Related Diseases for Tanycytic Ependymoma

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Diseases related to Tanycytic Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 164)
idRelated DiseaseScoreTop Affiliating Genes
1ependymoma11.8
2grubben de cock borghgraef syndrome10.8GFAP, SYP
3papillary glioneuronal tumor10.8GFAP, SYP
4bladder flat intraepithelial lesion10.8GFAP, SYP
5chiari malformation type 410.8GFAP, SYP
6cauda equina neoplasm10.8GFAP, SYP
7vulvar benign neoplasm10.7GFAP, SYP
8hypersensitivity reaction type ii disease10.7GFAP, SYP
9noninvasive malignant thymoma10.7GFAP, NF2
10brainstem intraparenchymal clear cell meningioma10.7GFAP, SYP
11chordoid glioma10.7GFAP, NF2
12renal pelvis inverted papilloma10.7GFAP, NF2
13pilomyxoid astrocytoma10.7GFAP, SYP
14choroid disease10.7GFAP, SYP
15vitamin metabolic disorder10.7GFAP, SYP
16pineoblastoma10.7GFAP, SYP
17external ear disease10.7GFAP, NF2
18malignant granular cell esophageal tumor10.7GFAP, SYP
19gallbladder adenoma10.7GFAP, SYP
20pineal parenchymal tumor of intermediate differenciation10.7GFAP, SYP
21tropical spastic paraparesis10.7GFAP, NF2
22multiple mucosal neuroma10.7GFAP, NF2
23childhood central nervous system primitive neuroectodermal neoplasm10.7GFAP, SMARCB1
24distal trisomy 16q10.6NF2, SMARCB1
25colonic pseudo-obstruction10.6GFAP, SMARCB1
26plexiform schwannoma10.6NF2, SMARCB1
27mesenchymoma10.6GFAP, SYP
28adult choroid plexus cancer10.6GFAP, SMARCB1
29large cell carcinoma10.6SMARCB1, SYP
30lactic acidosis10.6RBFOX3, SYP
31empty sella syndrome10.6GFAP, NES
32colloid carcinoma of the pancreas10.6RBFOX3, SYP
33anaplastic oligodendroglioma10.6GFAP, NES
34adult mesenchymal chondrosarcoma10.5SMARCB1, SYP
35cervical alveolar soft part sarcoma10.5GFAP, NES
36pancreatic cancer10.5GFAP, SMARCB1
37toxascariasis10.5NF2, SMARCB1
38surfactant metabolism dysfunction, pulmonary, 510.5NF2, SMARCB1
39sm-ahnmd10.5NES, SYP
40gallbladder leiomyosarcoma10.5GFAP, SYP
41uterine corpus epithelioid leiomyosarcoma10.5GFAP, NES
42grade iii astrocytoma10.5GFAP, SYP
43central centrifugal cicatricial alopecia10.5GFAP, NF2, SYP
44pearson syndrome10.4MEN1, SYP
45non-congenital cyst of kidney10.4NF2, SYP
46reactive arthritis10.4SMARCB1, SYP
47melanotic medulloblastoma10.4GFAP, SYP
48cervical benign neoplasm10.4GFAP, NES
49hyperammonemia due to carbonic anhydrase va deficiency10.4KDM6A, KMT2D
50pulmonary plasma cell granuloma10.4GFAP, SMARCB1, SYP

Graphical network of the top 20 diseases related to Tanycytic Ependymoma:



Diseases related to tanycytic ependymoma

Symptoms for Tanycytic Ependymoma

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Drugs & Therapeutics for Tanycytic Ependymoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Tanycytic Ependymoma

Genetic Tests for Tanycytic Ependymoma

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Anatomical Context for Tanycytic Ependymoma

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MalaCards organs/tissues related to Tanycytic Ependymoma:

34
Spinal cord

Animal Models for Tanycytic Ependymoma or affiliated genes

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MGI Mouse Phenotypes related to Tanycytic Ependymoma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.1KMT2D, MEN1, NF2, OLIG2, SMARCB1
2MP:00053697.9GFAP, KDM6A, KMT2D, MEN1, OLIG2, SMARCB1
3MP:00053786.8CHGA, GFAP, KDM6A, KMT2D, MEN1, NF2

Publications for Tanycytic Ependymoma

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Articles related to Tanycytic Ependymoma:

(show all 35)
idTitleAuthorsYear
1
Tanycytic ependymoma of cervical cord presenting with spontaneous intratumoral hemorrhage. (27033310)
2016
2
Imaging features of spinal tanycytic ependymoma. (26755489)
2016
3
Supratentorial tanycytic ependymoma in an adult male: case report and review of literature. (25873884)
2015
4
Features of intraventricular tanycytic ependymoma: report of a case and review of literature. (25031767)
2014
5
Tanycytic ependymoma in a 76-year-old Puerto Rican male. (25550817)
2014
6
Mystery case: tanycytic ependymoma of the conus medullaris: a rare cause of low back pain. (24960834)
2014
7
Pediatric supratentorial cortical tanycytic ependymoma associated with absence seizures. (24569174)
2014
8
Vestibular schwannoma or tanycytic ependymoma: Immunohistologic staining reveals. (25506503)
2014
9
Spinal tanycytic ependymoma associated with neurofibromatosis type 2. (24495349)
2014
10
intraventricular tanycytic ependymoma: an uncommon fibrillary variant. (24823737)
2014
11
Tanycytic ependymoma of the filum terminale associated with multiple endocrine neoplasia type 1: first reported case. (23562332)
2013
12
A 40-year-old male with an intraventricular tumor. Combined tanycytic ependymoma and subependymoma. (23587142)
2013
13
A cortical cystic epileptogenic lesion: tanycytic ependymoma. (23160807)
2013
14
Tanycytic ependymoma: a challenging histological diagnosis. (23476839)
2013
15
Tanycytic ependymoma of filum terminale: a case report. (22056760)
2012
16
Spinal tanycytic ependymoma with diffusion restriction on MRI. (22427295)
2012
17
A rare case of spinal dumbbell tanycytic ependymoma. (21270701)
2011
18
Supratentorial tanycytic ependymoma: an uncommon fibrillary ependymoma variant. (21877052)
2011
19
Spinal cord tanycytic ependymoma associated with neurofibromatosis type 2. (20403699)
2010
20
Rapid spontaneous malignant progression of supratentorial tanycytic ependymoma with sarcomatous features - "Ependymosarcoma". (19853384)
2010
21
Tanycytic ependymoma of the spinal cord with anaplastic cytological features. (19408091)
2009
22
Tanycytic ependymoma of the filum terminale with pleomorphic giant cells. (19856219)
2009
23
Tanycytic ependymoma arising from the right lateral ventricle: a case report and review of the literature. (18312548)
2008
24
Pediatric tanycytic ependymoma of the cauda equina: case report and review of the literature. (18401036)
2008
25
A case of tanycytic ependymoma arising from the cerebral hemisphere. (18095125)
2006
26
A case of cervicomedullary junction tanycytic ependymoma associated with marked cyst formation. (18095101)
2005
27
Intraventricular tanycytic ependymoma: case report and review of the literature. (15690137)
2005
28
Spinal tanycytic ependymoma with hematomyelia--case report--. (15782011)
2005
29
Supratentorial tanycytic ependymoma. (15519882)
2004
30
Tanycytic ependymoma of the spinal cord. Case report and review of the literature. (14735006)
2003
31
Tanycytic ependymoma in association with neurofibromatosis type 2. (11430494)
2001
32
Spinal tanycytic ependymoma associated with neurofibromatosis type 2--case report. (11760389)
2001
33
Intraoperative diagnosis of tanycytic ependymoma: pitfalls and differential diagnosis. (11285628)
2001
34
The tanycytic ependymoma of the lateral ventricle: case report. (10667826)
1999
35
Tanycytic ependymoma. (9090024)
1997

Variations for Tanycytic Ependymoma

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Expression for genes affiliated with Tanycytic Ependymoma

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Search GEO for disease gene expression data for Tanycytic Ependymoma.

Pathways for genes affiliated with Tanycytic Ependymoma

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Pathways related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5KMT2D, MEN1
29.1GFAP, NF2, RBFOX3, SYP
39.1KDM6A, MEN1, SMARCB1
48.8GFAP, NES, OLIG2, SYP

GO Terms for genes affiliated with Tanycytic Ependymoma

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Cellular components related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MLL3/4 complexGO:00446669.8KDM6A, KMT2D
2histone methyltransferase complexGO:00350978.8KDM6A, KMT2D, MEN1

Biological processes related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1histone H3-K4 methylationGO:00515689.7KDM6A, KMT2D
2brain developmentGO:00074209.0MEN1, NES, NF2

Molecular functions related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1histone-lysine N-methyltransferase activityGO:00180249.9KMT2D, MEN1
2protein bindingGO:00055155.5CHGA, GFAP, KDM6A, KMT2D, MEN1, NES

Sources for Tanycytic Ependymoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet