MCID: TNY001
MIFTS: 27

Tanycytic Ependymoma

Categories: Cancer diseases

Aliases & Classifications for Tanycytic Ependymoma

MalaCards integrated aliases for Tanycytic Ependymoma:

Name: Tanycytic Ependymoma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5504
NCIt 47 C6903
SNOMED-CT 64 397378002 57706008
UMLS 69 C1370500

Summaries for Tanycytic Ependymoma

MalaCards based summary : Tanycytic Ependymoma is related to ependymoma and devriendt syndrome. An important gene associated with Tanycytic Ependymoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include spinal cord and brain, and related phenotypes are Increased proliferation and muscle

Related Diseases for Tanycytic Ependymoma

Diseases related to Tanycytic Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 155)
id Related Disease Score Top Affiliating Genes
1 ependymoma 11.5
2 devriendt syndrome 10.8 GFAP SYP
3 hypogonadotropic hypogonadism-frontoparietal alopecia syndrome 10.8 GFAP SYP
4 dystonia 10.8 GFAP SYP
5 chilaiditi syndrome 10.8 GFAP SYP
6 cerebellar astrocytoma 10.8 GFAP SYP
7 renal pelvis urothelial papilloma 10.8 GFAP NF2
8 anovulation 10.8 GFAP NF2
9 cauda equina intradural extramedullary astrocytoma 10.8 GFAP SYP
10 rh isoimmunization 10.8 GFAP SYP
11 malignant granular cell myoblastoma 10.8 GFAP SYP
12 behcet's syndrome arthropathy 10.8 GFAP SYP
13 third cranial nerve disease 10.8 GFAP NF2
14 papillary glioneuronal tumor 10.8 GFAP SYP
15 central neurocytoma 10.7 GFAP SYP
16 demyelinating disease 10.7 GFAP NF2
17 benign pleural mesothelioma 10.7 GFAP NF2
18 subependymal giant cell astrocytoma 10.7 GFAP NF2
19 pneumothorax 10.7 GFAP SYP
20 nodular medulloblastoma 10.7 GFAP SMARCB1
21 distal trisomy 6q 10.7 NF2 SMARCB1
22 functional colonic disease 10.7 GFAP SMARCB1
23 thymus large cell carcinoma 10.6 SMARCB1 SYP
24 olfactory nerve neoplasm 10.6 RBFOX3 SYP
25 sella turcica neoplasm 10.6 GFAP NES
26 pacinian tumor 10.6 GFAP SYP
27 anaplastic plasmacytoma 10.6 GFAP NES
28 osteoclast-like giant cell neoplasm of the pancreas 10.6 RBFOX3 SYP
29 macular retinal edema 10.6 GFAP NES
30 pleural empyema 10.5 GFAP NF2 SYP
31 cauda equina neoplasm 10.5 GFAP NF2 SYP
32 anaplastic oligodendroglioma 10.5 GFAP NF2 SYP
33 ascaridiasis 10.5 NF2 SMARCB1
34 cataract 24, anterior polar 10.5 GFAP SMARCB1
35 aggressive systemic mastocytosis 10.5 GFAP NES
36 atypical choroid plexus papilloma 10.5 GFAP SMARCB1
37 lymphopenia 10.5 GFAP NES
38 pemphigus foliaceus 10.4 MEN1 SYP
39 myoblastoma 10.4 RBFOX3 SYP
40 breast reconstruction 10.4 GFAP NES
41 temporal lobe neoplasm 10.4 GFAP SMARCB1 SYP
42 melanotic medulloblastoma 10.4 GFAP SMARCB1 SYP
43 basosquamous carcinoma 10.4 GFAP NF2 SMARCB1
44 epidermal appendage tumor 10.4 GFAP RBFOX3 SYP
45 small cell sarcoma 10.4 NF2 SMARCB1 SYP
46 brain glioma 10.3 GFAP NES SYP
47 adenofibroma 10.3 GFAP NES SYP
48 axonal neuropathy 10.3 GFAP NES SYP
49 space motion sickness 10.3 GFAP NES SYP
50 mixed epithelial stromal tumour 10.3 GFAP NES SYP

Graphical network of the top 20 diseases related to Tanycytic Ependymoma:



Diseases related to Tanycytic Ependymoma

Symptoms & Phenotypes for Tanycytic Ependymoma

GenomeRNAi Phenotypes related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.8 MEN1 NF2 SMARCB1

MGI Mouse Phenotypes related to Tanycytic Ependymoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.63 GFAP KDM6A KMT2D MEN1 OLIG2 SMARCB1
2 neoplasm MP:0002006 9.35 KMT2D MEN1 NF2 OLIG2 SMARCB1
3 nervous system MP:0003631 9.23 GFAP KDM6A KMT2D MEN1 NF2 OLIG2

Drugs & Therapeutics for Tanycytic Ependymoma

Search Clinical Trials , NIH Clinical Center for Tanycytic Ependymoma

Genetic Tests for Tanycytic Ependymoma

Anatomical Context for Tanycytic Ependymoma

MalaCards organs/tissues related to Tanycytic Ependymoma:

39
Spinal Cord, Brain

Publications for Tanycytic Ependymoma

Articles related to Tanycytic Ependymoma:

(show all 39)
id Title Authors Year
1
Two Cases of Spinal Tanycytic Ependymoma Associated with Neurofibromatosis Type 2. ( 28345553 )
2017
2
Tanycytic ependymoma of the brain stem, presentations of rare cystic disease variants and review of literature. ( 28884561 )
2017
3
Tanycytic ependymoma of cervical cord presenting with spontaneous intratumoral hemorrhage. ( 27033310 )
2016
4
Tanycytic ependymoma vs pilocytic astrocytoma? Pitfalls in diagnosis. ( 27773093 )
2016
5
Squash cytology of tanycytic ependymoma: A report of two cases. ( 27879059 )
2016
6
Imaging features of spinal tanycytic ependymoma. ( 26755489 )
2016
7
Supratentorial tanycytic ependymoma in an adult male: case report and review of literature. ( 25873884 )
2015
8
Features of intraventricular tanycytic ependymoma: report of a case and review of literature. ( 25031767 )
2014
9
Tanycytic ependymoma in a 76-year-old Puerto Rican male. ( 25550817 )
2014
10
intraventricular tanycytic ependymoma: an uncommon fibrillary variant. ( 24823737 )
2014
11
Mystery case: tanycytic ependymoma of the conus medullaris: a rare cause of low back pain. ( 24960834 )
2014
12
Spinal tanycytic ependymoma associated with neurofibromatosis type 2. ( 24495349 )
2014
13
Pediatric supratentorial cortical tanycytic ependymoma associated with absence seizures. ( 24569174 )
2014
14
Vestibular schwannoma or tanycytic ependymoma: Immunohistologic staining reveals. ( 25506503 )
2014
15
Tanycytic ependymoma of the filum terminale associated with multiple endocrine neoplasia type 1: first reported case. ( 23562332 )
2013
16
A 40-year-old male with an intraventricular tumor. Combined tanycytic ependymoma and subependymoma. ( 23587142 )
2013
17
A cortical cystic epileptogenic lesion: tanycytic ependymoma. ( 23160807 )
2013
18
Tanycytic ependymoma: a challenging histological diagnosis. ( 23476839 )
2013
19
Tanycytic ependymoma of filum terminale: a case report. ( 22056760 )
2012
20
Spinal tanycytic ependymoma with diffusion restriction on MRI. ( 22427295 )
2012
21
A rare case of spinal dumbbell tanycytic ependymoma. ( 21270701 )
2011
22
Supratentorial tanycytic ependymoma: an uncommon fibrillary ependymoma variant. ( 21877052 )
2011
23
Spinal cord tanycytic ependymoma associated with neurofibromatosis type 2. ( 20403699 )
2010
24
Rapid spontaneous malignant progression of supratentorial tanycytic ependymoma with sarcomatous features - "Ependymosarcoma". ( 19853384 )
2010
25
Tanycytic ependymoma of the filum terminale with pleomorphic giant cells. ( 19856219 )
2009
26
Tanycytic ependymoma of the spinal cord with anaplastic cytological features. ( 19408091 )
2009
27
Pediatric tanycytic ependymoma of the cauda equina: case report and review of the literature. ( 18401036 )
2008
28
Tanycytic ependymoma arising from the right lateral ventricle: a case report and review of the literature. ( 18312548 )
2008
29
A case of tanycytic ependymoma arising from the cerebral hemisphere. ( 18095125 )
2006
30
A case of cervicomedullary junction tanycytic ependymoma associated with marked cyst formation. ( 18095101 )
2005
31
Spinal tanycytic ependymoma with hematomyelia--case report--. ( 15782011 )
2005
32
Intraventricular tanycytic ependymoma: case report and review of the literature. ( 15690137 )
2005
33
Supratentorial tanycytic ependymoma. ( 15519882 )
2004
34
Tanycytic ependymoma of the spinal cord. Case report and review of the literature. ( 14735006 )
2003
35
Intraoperative diagnosis of tanycytic ependymoma: pitfalls and differential diagnosis. ( 11285628 )
2001
36
Tanycytic ependymoma in association with neurofibromatosis type 2. ( 11430494 )
2001
37
Spinal tanycytic ependymoma associated with neurofibromatosis type 2--case report. ( 11760389 )
2001
38
The tanycytic ependymoma of the lateral ventricle: case report. ( 10667826 )
1999
39
Tanycytic ependymoma. ( 9090024 )
1997

Variations for Tanycytic Ependymoma

Expression for Tanycytic Ependymoma

Search GEO for disease gene expression data for Tanycytic Ependymoma.

Pathways for Tanycytic Ependymoma

Pathways related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.77 GFAP NF2 RBFOX3 SYP
2 10.83 GFAP NES OLIG2 SYP

GO Terms for Tanycytic Ependymoma

Cellular components related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 MLL3/4 complex GO:0044666 8.96 KDM6A KMT2D
2 histone methyltransferase complex GO:0035097 8.8 KDM6A KMT2D MEN1

Biological processes related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.46 NES OLIG2 RBFOX3 SMARCB1
2 histone H3-K4 methylation GO:0051568 8.96 KDM6A KMT2D
3 covalent chromatin modification GO:0016569 8.92 KDM6A KMT2D MEN1 SMARCB1

Sources for Tanycytic Ependymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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