MCID: TNY001
MIFTS: 29

Tanycytic Ependymoma

Categories: Cancer diseases

Aliases & Classifications for Tanycytic Ependymoma

MalaCards integrated aliases for Tanycytic Ependymoma:

Name: Tanycytic Ependymoma 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5504
NCIt 46 C6903
SNOMED-CT 64 397378002 57706008
UMLS 69 C1370500

Summaries for Tanycytic Ependymoma

MalaCards based summary : Tanycytic Ependymoma is related to ependymoma and pilocytic astrocytoma. An important gene associated with Tanycytic Ependymoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include spinal cord and brain, and related phenotypes are Increased proliferation and muscle

Related Diseases for Tanycytic Ependymoma

Diseases related to Tanycytic Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 ependymoma 32.6 GFAP NES NF2 SYP
2 pilocytic astrocytoma 30.2 GFAP OLIG2 SYP
3 astrocytoma 29.7 GFAP NES OLIG2 SYP
4 multiple endocrine neoplasia, type i 29.5 CHGA MEN1 SYP
5 subependymoma 29.4 CHGA GFAP NES SYP
6 desmoplastic infantile ganglioglioma 10.6 GFAP SYP
7 extraventricular neurocytoma 10.6 GFAP SYP
8 lung combined type small cell carcinoma 10.6 GFAP SYP
9 cerebral convexity meningioma 10.5 GFAP NF2
10 pilomyxoid astrocytoma 10.5 GFAP SYP
11 intraventricular meningioma 10.5 GFAP NF2
12 subependymal glioma 10.5 GFAP SYP
13 chiari malformation 10.5 GFAP SYP
14 cornea cancer 10.5 GFAP NF2
15 cerebral neuroblastoma 10.5 GFAP SYP
16 pineal gland cancer 10.5 GFAP SYP
17 spinal cancer 10.5 GFAP NF2
18 melanotic neuroectodermal tumor 10.5 GFAP SYP
19 chordoid glioma 10.5 GFAP NF2
20 angiocentric glioma 10.5 GFAP SYP
21 obstructive hydrocephalus 10.5 GFAP SYP
22 plexiform schwannoma 10.5 GFAP NF2
23 atypical neurofibroma 10.5 GFAP NF2
24 malignant ependymoma 10.5 GFAP NF2
25 pineoblastoma 10.5 GFAP SYP
26 papilloma of choroid plexus 10.5 GFAP SYP
27 melanotic medulloblastoma 10.5 GFAP SMARCB1
28 monosomy 22 10.4 NF2 SMARCB1
29 nodular medulloblastoma 10.4 GFAP SMARCB1
30 schwannomatosis 1 10.4 NF2 SMARCB1
31 extraosseous chondrosarcoma 10.4 SMARCB1 SYP
32 cystic teratoma 10.4 GFAP SYP
33 central nervous system teratoma 10.4 GFAP NES
34 anaplastic ganglioglioma 10.4 GFAP NES
35 sella turcica neoplasm 10.4 RBFOX3 SYP
36 tuberculum sellae meningioma 10.4 RBFOX3 SYP
37 central nervous system germ cell tumor 10.4 GFAP NES
38 benign ependymoma 10.4 GFAP NF2 SYP
39 anaplastic ependymoma 10.4 GFAP NF2 SYP
40 ependymoblastoma 10.3 GFAP NES
41 choroid plexus cancer 10.3 GFAP SMARCB1
42 neurofibromatosis, type iv, of riccardi 10.3
43 small cell sarcoma 10.3 NF2 SMARCB1
44 neurilemmomatosis 10.3 NF2 SMARCB1
45 gliomatosis cerebri 10.3 GFAP NES
46 pineal parenchymal tumor of intermediate differentiation 10.3 RBFOX3 SYP
47 brain ischemia 10.3 GFAP NES
48 pancreatic somatostatinoma 10.3 MEN1 SYP
49 atypical teratoid rhabdoid tumor 10.3 GFAP SMARCB1 SYP
50 medullomyoblastoma 10.3 GFAP SMARCB1 SYP

Graphical network of the top 20 diseases related to Tanycytic Ependymoma:



Diseases related to Tanycytic Ependymoma

Symptoms & Phenotypes for Tanycytic Ependymoma

GenomeRNAi Phenotypes related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.8 MEN1 NF2 SMARCB1

MGI Mouse Phenotypes related to Tanycytic Ependymoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.63 GFAP KDM6A KMT2D MEN1 OLIG2 SMARCB1
2 neoplasm MP:0002006 9.35 SMARCB1 KMT2D MEN1 NF2 OLIG2
3 nervous system MP:0003631 9.23 SMARCB1 SYP GFAP KDM6A KMT2D MEN1

Drugs & Therapeutics for Tanycytic Ependymoma

Search Clinical Trials , NIH Clinical Center for Tanycytic Ependymoma

Genetic Tests for Tanycytic Ependymoma

Anatomical Context for Tanycytic Ependymoma

MalaCards organs/tissues related to Tanycytic Ependymoma:

38
Spinal Cord, Brain

Publications for Tanycytic Ependymoma

Articles related to Tanycytic Ependymoma:

(show all 38)
# Title Authors Year
1
Two Cases of Spinal Tanycytic Ependymoma Associated with Neurofibromatosis Type 2. ( 28345553 )
2017
2
Tanycytic ependymoma of the brain stem, presentations of rare cystic disease variants and review of literature. ( 28884561 )
2017
3
Tanycytic ependymoma vs pilocytic astrocytoma? Pitfalls in diagnosis. ( 27773093 )
2016
4
Squash cytology of tanycytic ependymoma: A report of two cases. ( 27879059 )
2016
5
Tanycytic ependymoma of cervical cord presenting with spontaneous intratumoral hemorrhage. ( 27033310 )
2016
6
Imaging features of spinal tanycytic ependymoma. ( 26755489 )
2016
7
Supratentorial tanycytic ependymoma in an adult male: case report and review of literature. ( 25873884 )
2015
8
Vestibular schwannoma or tanycytic ependymoma: Immunohistologic staining reveals. ( 25506503 )
2014
9
Tanycytic ependymoma in a 76-year-old Puerto Rican male. ( 25550817 )
2014
10
Spinal tanycytic ependymoma associated with neurofibromatosis type 2. ( 24495349 )
2014
11
Mystery case: tanycytic ependymoma of the conus medullaris: a rare cause of low back pain. ( 24960834 )
2014
12
Pediatric supratentorial cortical tanycytic ependymoma associated with absence seizures. ( 24569174 )
2014
13
intraventricular tanycytic ependymoma: an uncommon fibrillary variant. ( 24823737 )
2014
14
Features of intraventricular tanycytic ependymoma: report of a case and review of literature. ( 25031767 )
2014
15
Tanycytic ependymoma: a challenging histological diagnosis. ( 23476839 )
2013
16
A 40-year-old male with an intraventricular tumor. Combined tanycytic ependymoma and subependymoma. ( 23587142 )
2013
17
Tanycytic ependymoma of the filum terminale associated with multiple endocrine neoplasia type 1: first reported case. ( 23562332 )
2013
18
A cortical cystic epileptogenic lesion: tanycytic ependymoma. ( 23160807 )
2013
19
Tanycytic ependymoma of filum terminale: a case report. ( 22056760 )
2012
20
Spinal tanycytic ependymoma with diffusion restriction on MRI. ( 22427295 )
2012
21
A rare case of spinal dumbbell tanycytic ependymoma. ( 21270701 )
2011
22
Supratentorial tanycytic ependymoma: an uncommon fibrillary ependymoma variant. ( 21877052 )
2011
23
Rapid spontaneous malignant progression of supratentorial tanycytic ependymoma with sarcomatous features - "Ependymosarcoma". ( 19853384 )
2010
24
Spinal cord tanycytic ependymoma associated with neurofibromatosis type 2. ( 20403699 )
2010
25
Tanycytic ependymoma of the spinal cord with anaplastic cytological features. ( 19408091 )
2009
26
Pediatric tanycytic ependymoma of the cauda equina: case report and review of the literature. ( 18401036 )
2008
27
Tanycytic ependymoma arising from the right lateral ventricle: a case report and review of the literature. ( 18312548 )
2008
28
A case of tanycytic ependymoma arising from the cerebral hemisphere. ( 18095125 )
2006
29
A case of cervicomedullary junction tanycytic ependymoma associated with marked cyst formation. ( 18095101 )
2005
30
Spinal tanycytic ependymoma with hematomyelia--case report--. ( 15782011 )
2005
31
Intraventricular tanycytic ependymoma: case report and review of the literature. ( 15690137 )
2005
32
Supratentorial tanycytic ependymoma. ( 15519882 )
2004
33
Tanycytic ependymoma of the spinal cord. Case report and review of the literature. ( 14735006 )
2003
34
Spinal tanycytic ependymoma associated with neurofibromatosis type 2--case report. ( 11760389 )
2001
35
Intraoperative diagnosis of tanycytic ependymoma: pitfalls and differential diagnosis. ( 11285628 )
2001
36
Tanycytic ependymoma in association with neurofibromatosis type 2. ( 11430494 )
2001
37
The tanycytic ependymoma of the lateral ventricle: case report. ( 10667826 )
1999
38
Tanycytic ependymoma. ( 9090024 )
1997

Variations for Tanycytic Ependymoma

Expression for Tanycytic Ependymoma

Search GEO for disease gene expression data for Tanycytic Ependymoma.

Pathways for Tanycytic Ependymoma

Pathways related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.79 GFAP NF2 RBFOX3 SYP
2 10.82 GFAP NES OLIG2 SYP

GO Terms for Tanycytic Ependymoma

Cellular components related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MLL3/4 complex GO:0044666 8.96 KDM6A KMT2D
2 histone methyltransferase complex GO:0035097 8.8 KDM6A KMT2D MEN1

Biological processes related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.46 NES OLIG2 RBFOX3 SMARCB1
2 histone H3-K4 methylation GO:0051568 8.96 KDM6A KMT2D
3 covalent chromatin modification GO:0016569 8.92 KDM6A KMT2D MEN1 SMARCB1

Sources for Tanycytic Ependymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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