Tardbp-related Amyotrophic Lateral Sclerosis malady

MalaCards: Tardbp-related Amyotrophic Lateral Sclerosis, also known as amyotrophic lateral sclerosis 10 (disorder), is related to amyotrophic lateral sclerosis and lateral sclerosis. An important gene associated with Tardbp-related Amyotrophic Lateral Sclerosis is TARDBP (TAR DNA binding protein). The drug riluzole has been mentioned in the context of this disorder.

GeneReviews summary for tardbp-als

tardbp-related amyotrophic lateral sclerosis 15 16 amyotrophic lateral sclerosis 10 (disorder) 43 amyotrophic lateral sclerosis 10 16

amyotrophic lateral sclerosis 43 als 10 16

Diseases related to tardbp-related amyotrophic lateral sclerosis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 420)

id	Related Disease	Score	Top Affiliating Genes
1	amyotrophic lateral sclerosis	16.1
2	lateral sclerosis	16.0
3	amyotrophic lateral sclerosis (als)	12.2
4	dementia	11.6
5	motor neuron disease	10.3
6	amyotrophic lateral sclerosis with frontotemporal dementia	10.2
7	amyotrophic lateral sclerosis, type 4	9.9
8	amyotrophic lateral sclerosis type 2	9.9
9	frontotemporal dementia	9.7
10	neurodegeneration	9.7
11	alzheimer's disease	9.5
12	amyotrophic lateral sclerosis type 8	9.5
13	setx-related amyotrophic lateral sclerosis	9.5
14	amyotrophic lateral sclerosis type 11	9.3
15	amyotrophic lateral sclerosis type 3	9.3
16	amyotrophic lateral sclerosis type 7	9.3
17	amyotrophic lateral sclerosis type 9	9.3
18	amyotrophic lateral sclerosis-parkinsonism/dementia complex 1	9.3
19	fig4-related amyotrophic lateral sclerosis	9.3
20	neurodegenerative disease	9.3
21	parkinson's disease	9.0
22	ubqln2-related amyotrophic lateral sclerosis/frontotemporal dementia	9.0
23	vapb-related amyotrophic lateral sclerosis	9.0
24	amyotrophic lateral sclerosis type 10	9.0
25	amyotrophic lateral sclerosis type 5	9.0
26	amyotrophic lateral sclerosis type 6	9.0
27	muscular atrophy	9.0
28	optn-related amyotrophic lateral sclerosis	8.6
29	pfn1-related amyotrophic lateral sclerosis	8.6
30	sod1-related amyotrophic lateral sclerosis	8.6
31	amyotrophic lateral sclerosis multi-gene panels	8.6
32	spinal muscular atrophy	8.6
33	amyotrophic lateral sclerosis-parkinsonism/dementia complex 2	8.6
34	vcp-related amyotrophic lateral sclerosis/frontotemporal dementia	8.6
35	amyotrophic lateral sclerosis-5, juvenile recessive	8.6
36	amyotrophic lateral sclerosis 6, autosomal recessive, with or without frontotemporal dementia	8.6
37	amyotrophic lateral sclerosis 10, with or without ftd	8.6
38	amyotrophic lateral sclerosis, due to sod1 deficiency	8.6
39	amyotrophic lateral sclerosis, chmp2b-related	8.6
40	ang-related amyotrophic lateral sclerosis	8.6
41	autosomal recessive juvenile amyotrophic lateral sclerosis	8.6
42	c9orf72-related amyotrophic lateral sclerosis/frontotemporal dementia	8.6
43	fus-related amyotrophic lateral sclerosis	8.6
44	al amyloidosis	8.2
45	down syndrome	8.1
46	foot drop	8.1
47	hereditary neuropathies	8.1
48	inclusion body myopathy with early-onset paget disease and frontotemporal dementia	8.1
49	multiple system atrophy	8.1
50	poliomyelitis	8.1

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 riluzole

Genetic tests related to tardbp-related amyotrophic lateral sclerosis:

id	Genetic test	Affiliating Genes
1	Tardbp-related Amyotrophic Lateral Sclerosis clinical/research	TARDBP

Genes related to tardbp-related amyotrophic lateral sclerosis according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	TARDBP	TAR DNA binding protein	11.1	Disorders