MCID: TRD001
MIFTS: 13

Tardbp-Related Amyotrophic Lateral Sclerosis malady

Genetic diseases, Neuronal diseases, Rare diseases, Mental diseases categories

Aliases & Classifications for Tardbp-Related Amyotrophic Lateral Sclerosis

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Aliases & Descriptions for Tardbp-Related Amyotrophic Lateral Sclerosis:

Name: Tardbp-Related Amyotrophic Lateral Sclerosis 21 22
Amyotrophic Lateral Sclerosis 10, with 22
 
Als 10 22


Classifications:



Summaries for Tardbp-Related Amyotrophic Lateral Sclerosis

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MalaCards based summary: Tardbp-Related Amyotrophic Lateral Sclerosis, also known as amyotrophic lateral sclerosis 10, with, is related to amyotrophic lateral sclerosis type 10 and amyotrophic lateral sclerosis 10, with or without ftd. An important gene associated with Tardbp-Related Amyotrophic Lateral Sclerosis is TARDBP (TAR DNA Binding Protein).

GeneReviews summary for tardbp-als

Related Diseases for Tardbp-Related Amyotrophic Lateral Sclerosis

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Diseases in the Amyotrophic Lateral Sclerosis 2, Juvenile family:

Amyotrophic Lateral Sclerosis 19 Amyotrophic Lateral Sclerosis 17
Amyotrophic Lateral Sclerosis 21 Amyotrophic Lateral Sclerosis 11
Amyotrophic Lateral Sclerosis 16, Juvenile Amyotrophic Lateral Sclerosis 4, Juvenile
Amyotrophic Lateral Sclerosis 12 Amyotrophic Lateral Sclerosis 20
Amyotrophic Lateral Sclerosis 9 Amyotrophic Lateral Sclerosis 5, Juvenile
Amyotrophic Lateral Sclerosis 18 Amyotrophic Lateral Sclerosis 3
Amyotrophic Lateral Sclerosis 7 Amyotrophic Lateral Sclerosis 8
Amyotrophic Lateral Sclerosis 1 Amyotrophic Lateral Sclerosis Type 5
Amyotrophic Lateral Sclerosis Type 4 Amyotrophic Lateral Sclerosis Type 6
Amyotrophic Lateral Sclerosis Type 2 Amyotrophic Lateral Sclerosis Type 10
Amyotrophic Lateral Sclerosis Type 16 Amyotrophic Lateral Sclerosis Type 15
Amyotrophic Lateral Sclerosis Type 14 tardbp-related amyotrophic lateral sclerosis
Als5-Related Amyotrophic Lateral Sclerosis Erbb4-Related Amyotrophic Lateral Sclerosis
Ang-Related Amyotrophic Lateral Sclerosis Autosomal Recessive Juvenile Amyotrophic Lateral Sclerosis
Fig4-Related Amyotrophic Lateral Sclerosis Fus-Related Amyotrophic Lateral Sclerosis
Optn-Related Amyotrophic Lateral Sclerosis Pfn1-Related Amyotrophic Lateral Sclerosis
Setx-Related Amyotrophic Lateral Sclerosis Sigmar1-Related Amyotrophic Lateral Sclerosis
Sod1-Related Amyotrophic Lateral Sclerosis Vapb-Related Amyotrophic Lateral Sclerosis

Diseases related to Tardbp-Related Amyotrophic Lateral Sclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1amyotrophic lateral sclerosis type 1010.5
2amyotrophic lateral sclerosis 10, with or without ftd10.5
3lateral sclerosis10.5

Symptoms for Tardbp-Related Amyotrophic Lateral Sclerosis

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Drugs & Therapeutics for Tardbp-Related Amyotrophic Lateral Sclerosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Tardbp-Related Amyotrophic Lateral Sclerosis

Genetic Tests for Tardbp-Related Amyotrophic Lateral Sclerosis

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Genetic tests related to Tardbp-Related Amyotrophic Lateral Sclerosis:

id Genetic test Affiliating Genes
1 Tardbp-Related Amyotrophic Lateral Sclerosis22 TARDBP

Anatomical Context for Tardbp-Related Amyotrophic Lateral Sclerosis

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Animal Models for Tardbp-Related Amyotrophic Lateral Sclerosis or affiliated genes

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Publications for Tardbp-Related Amyotrophic Lateral Sclerosis

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Articles related to Tardbp-Related Amyotrophic Lateral Sclerosis:

idTitleAuthorsYear
1
TARDBP-Related Amyotrophic Lateral Sclerosis (20301761)
1993

Variations for Tardbp-Related Amyotrophic Lateral Sclerosis

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Clinvar genetic disease variations for Tardbp-Related Amyotrophic Lateral Sclerosis:

5 (show all 16)
id Gene Variation Type Significance SNP ID Assembly Location
1TARDBPNM_007375.3(TARDBP): c.1150G> C (p.Gly384Arg)single nucleotide variantPathogenicrs797044594GRCh38Chr 1, 11022559: 11022559
2TARDBPNM_007375.3(TARDBP): c.1153T> G (p.Trp385Gly)single nucleotide variantPathogenicrs797044595GRCh38Chr 1, 11022562: 11022562
3TARDBPNM_007375.3(TARDBP): c.*83T> Csingle nucleotide variantPathogenicrs80356744GRCh37Chr 1, 11082794: 11082794
4TARDBPNM_007375.3(TARDBP): c.1144G> A (p.Ala382Thr)single nucleotide variantPathogenicrs367543041GRCh37Chr 1, 11082610: 11082610
5TARDBPNM_007375.3(TARDBP): c.881G> T (p.Gly294Val)single nucleotide variantPathogenicrs80356721GRCh37Chr 1, 11082347: 11082347
6TARDBPNM_007375.3(TARDBP): c.883G> A (p.Gly295Ser)single nucleotide variantPathogenicrs80356723GRCh37Chr 1, 11082349: 11082349
7TARDBPNM_007375.3(TARDBP): c.1009A> G (p.Met337Val)single nucleotide variantPathogenicrs80356730GRCh37Chr 1, 11082475: 11082475
8TARDBPNM_007375.3(TARDBP): c.991C> A (p.Gln331Lys)single nucleotide variantPathogenicrs80356727GRCh37Chr 1, 11082457: 11082457
9TARDBPNM_007375.3(TARDBP): c.881G> C (p.Gly294Ala)single nucleotide variantPathogenicrs80356721GRCh37Chr 1, 11082347: 11082347
10TARDBPNM_007375.3(TARDBP): c.869G> C (p.Gly290Ala)single nucleotide variantPathogenicrs121908395GRCh37Chr 1, 11082335: 11082335
11TARDBPNM_007375.3(TARDBP): c.892G> A (p.Gly298Ser)single nucleotide variantPathogenicrs4884357GRCh37Chr 1, 11082358: 11082358
12TARDBPNM_007375.3(TARDBP): c.506A> G (p.Asp169Gly)single nucleotide variantPathogenicrs80356717GRCh37Chr 1, 11078893: 11078893
13TARDBPNM_007375.3(TARDBP): c.1042G> T (p.Gly348Cys)single nucleotide variantPathogenicrs80356733GRCh37Chr 1, 11082508: 11082508
14TARDBPNM_007375.3(TARDBP): c.1028A> G (p.Gln343Arg)single nucleotide variantPathogenicrs80356731GRCh37Chr 1, 11082494: 11082494
15TARDBPNM_007375.3(TARDBP): c.943G> A (p.Ala315Thr)single nucleotide variantPathogenicrs80356726GRCh37Chr 1, 11082409: 11082409
16TARDBPNM_007375.3(TARDBP): c.*697G> Asingle nucleotide variantPathogenicrs387906334GRCh37Chr 1, 11083408: 11083408

Expression for genes affiliated with Tardbp-Related Amyotrophic Lateral Sclerosis

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Search GEO for disease gene expression data for Tardbp-Related Amyotrophic Lateral Sclerosis.

Pathways for genes affiliated with Tardbp-Related Amyotrophic Lateral Sclerosis

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GO Terms for genes affiliated with Tardbp-Related Amyotrophic Lateral Sclerosis

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Sources for Tardbp-Related Amyotrophic Lateral Sclerosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet