MCID: TRD001
MIFTS: 12

Tardbp-Related Amyotrophic Lateral Sclerosis malady

Categories: Genetic diseases, Neuronal diseases, Rare diseases, Mental diseases

Aliases & Classifications for Tardbp-Related Amyotrophic Lateral Sclerosis

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Aliases & Descriptions for Tardbp-Related Amyotrophic Lateral Sclerosis:

Name: Tardbp-Related Amyotrophic Lateral Sclerosis 21 22
Amyotrophic Lateral Sclerosis 10 22 65
 
Als 10 22

Classifications:



External Ids:

UMLS65 C3502417

Summaries for Tardbp-Related Amyotrophic Lateral Sclerosis

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MalaCards based summary: Tardbp-Related Amyotrophic Lateral Sclerosis, also known as amyotrophic lateral sclerosis 10, is related to amyotrophic lateral sclerosis 10, with or without ftd and amyotrophic lateral sclerosis type 10. An important gene associated with Tardbp-Related Amyotrophic Lateral Sclerosis is TARDBP (TAR DNA Binding Protein).

GeneReviews summary for NBK5942

Related Diseases for Tardbp-Related Amyotrophic Lateral Sclerosis

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Diseases in the Amyotrophic Lateral Sclerosis 2, Juvenile family:

Amyotrophic Lateral Sclerosis 19 Amyotrophic Lateral Sclerosis 17
Amyotrophic Lateral Sclerosis 21 Amyotrophic Lateral Sclerosis 11
Amyotrophic Lateral Sclerosis 16, Juvenile Amyotrophic Lateral Sclerosis 4, Juvenile
Amyotrophic Lateral Sclerosis 12 Amyotrophic Lateral Sclerosis 20
Amyotrophic Lateral Sclerosis 9 Amyotrophic Lateral Sclerosis 5, Juvenile
Amyotrophic Lateral Sclerosis 18 Amyotrophic Lateral Sclerosis 3
Amyotrophic Lateral Sclerosis 7 Amyotrophic Lateral Sclerosis 8
Amyotrophic Lateral Sclerosis 1 Amyotrophic Lateral Sclerosis Type 2
Amyotrophic Lateral Sclerosis Type 4 Amyotrophic Lateral Sclerosis Type 5
Amyotrophic Lateral Sclerosis Type 6 Amyotrophic Lateral Sclerosis Type 10
Amyotrophic Lateral Sclerosis Type 14 Amyotrophic Lateral Sclerosis Type 15
Amyotrophic Lateral Sclerosis Type 16 tardbp-related amyotrophic lateral sclerosis
Als5-Related Amyotrophic Lateral Sclerosis Erbb4-Related Amyotrophic Lateral Sclerosis
Hnrnpa1-Related Amyotrophic Lateral Sclerosis Ang-Related Amyotrophic Lateral Sclerosis
Autosomal Recessive Juvenile Amyotrophic Lateral Sclerosis Fig4-Related Amyotrophic Lateral Sclerosis
Fus-Related Amyotrophic Lateral Sclerosis Optn-Related Amyotrophic Lateral Sclerosis
Pfn1-Related Amyotrophic Lateral Sclerosis Setx-Related Amyotrophic Lateral Sclerosis
Sigmar1-Related Amyotrophic Lateral Sclerosis Sod1-Related Amyotrophic Lateral Sclerosis
Vapb-Related Amyotrophic Lateral Sclerosis

Diseases related to Tardbp-Related Amyotrophic Lateral Sclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1amyotrophic lateral sclerosis 10, with or without ftd12.9
2amyotrophic lateral sclerosis type 1012.0
3chediak-higashi syndrome10.4

Symptoms for Tardbp-Related Amyotrophic Lateral Sclerosis

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Drugs & Therapeutics for Tardbp-Related Amyotrophic Lateral Sclerosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Tardbp-Related Amyotrophic Lateral Sclerosis

Genetic Tests for Tardbp-Related Amyotrophic Lateral Sclerosis

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Genetic tests related to Tardbp-Related Amyotrophic Lateral Sclerosis:

id Genetic test Affiliating Genes
1 Tardbp-Related Amyotrophic Lateral Sclerosis22 TARDBP

Anatomical Context for Tardbp-Related Amyotrophic Lateral Sclerosis

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Animal Models for Tardbp-Related Amyotrophic Lateral Sclerosis or affiliated genes

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Publications for Tardbp-Related Amyotrophic Lateral Sclerosis

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Articles related to Tardbp-Related Amyotrophic Lateral Sclerosis:

idTitleAuthorsYear
1
PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK-and IRE1alpha-mediated unfolded protein response. (23103912)
2012

Variations for Tardbp-Related Amyotrophic Lateral Sclerosis

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Clinvar genetic disease variations for Tardbp-Related Amyotrophic Lateral Sclerosis:

5
id Gene Variation Type Significance SNP ID Assembly Location
1TARDBPNM_007375.3(TARDBP): c.1144G> A (p.Ala382Thr)single nucleotide variantPathogenicrs367543041GRCh37Chr 1, 11082610: 11082610
2TARDBPNM_007375.3(TARDBP): c.*697G> Asingle nucleotide variantPathogenicrs387906334GRCh37Chr 1, 11083408: 11083408

Expression for genes affiliated with Tardbp-Related Amyotrophic Lateral Sclerosis

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Search GEO for disease gene expression data for Tardbp-Related Amyotrophic Lateral Sclerosis.

Pathways for genes affiliated with Tardbp-Related Amyotrophic Lateral Sclerosis

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GO Terms for genes affiliated with Tardbp-Related Amyotrophic Lateral Sclerosis

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Sources for Tardbp-Related Amyotrophic Lateral Sclerosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet