MCID: TMP012
MIFTS: 24

Temple Syndrome malady

Genetic diseases, Neuronal diseases, Endocrine diseases, Fetal diseases, Rare diseases categories

Aliases & Classifications for Temple Syndrome

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Sources:
46OMIM, 20GeneTests, 48Orphanet, 22GTR, 26ICD10 via Orphanet
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Summaries for Temple Syndrome

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OMIM:46 Temple syndrome is a short stature disorder of imprinting. The cardinal features are low birth weight, hypotonia and... (616222) more...

MalaCards based summary: Temple Syndrome, also known as maternal uniparental disomy of chromosome 14, is related to prader-willi syndrome and west syndrome. An important gene associated with Temple Syndrome is DLK1 (delta-like 1 homolog (Drosophila)). Related mouse phenotypes are muscle and liver/biliary system.

Related Diseases for Temple Syndrome

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Diseases related to Temple Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1prader-willi syndrome10.5
2west syndrome10.5
3precocious puberty10.5
4central precocious puberty10.5
5houlston ironton temple syndrome10.4
6curry jones syndrome10.1
7atrioventricular defect - blepharophimosis -radial defects10.1

Graphical network of diseases related to Temple Syndrome:



Diseases related to temple syndrome

Symptoms for Temple Syndrome

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Clinical features from OMIM:

616222

Drugs & Therapeutics for Temple Syndrome

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Drug clinical trials:

Search ClinicalTrials for Temple Syndrome

Search NIH Clinical Center for Temple Syndrome

Genetic Tests for Temple Syndrome

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Genetic tests related to Temple Syndrome:

id Genetic test Affiliating Genes
1 Maternal Uniparental Disomy, Chromosome 1420
2 Uniparental Disomy of Chromosome 14, Maternal22

Anatomical Context for Temple Syndrome

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Animal Models for Temple Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Temple Syndrome:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.0DLK1, MEG3
2MP:00053708.7DLK1, MEG3
3MP:00053808.6DLK1, MEG3, RTL1
4MP:00053788.5DLK1, MEG3, RTL1
5MP:00107688.4RTL1, MEG3, DLK1

Publications for Temple Syndrome

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Variations for Temple Syndrome

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Expression for genes affiliated with Temple Syndrome

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Search GEO for disease gene expression data for Temple Syndrome.

Pathways for genes affiliated with Temple Syndrome

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Compounds for genes affiliated with Temple Syndrome

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GO Terms for genes affiliated with Temple Syndrome

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Biological processes related to Temple Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1multicellular organismal developmentGO:00072759.3DLK1, RTL1

Sources for Temple Syndrome

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet