MCID: TMP001
MIFTS: 50

Temporal Lobe Epilepsy malady

Category: Neuronal diseases

Aliases & Classifications for Temporal Lobe Epilepsy

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Aliases & Descriptions for Temporal Lobe Epilepsy:

Name: Temporal Lobe Epilepsy 35 11 13
Epilepsy, Temporal Lobe 11 39 68
 
Epilepsy Temporal Lobe 50

Classifications:



External Ids:

Disease Ontology11 DOID:3328
MeSH39 D004833

Summaries for Temporal Lobe Epilepsy

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Wikipedia:71 Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent,... more...

MalaCards based summary: Temporal Lobe Epilepsy, also known as epilepsy, temporal lobe, is related to idiopathic generalized epilepsy and personality disorder, and has symptoms including seizures and seizures, focal. An important gene associated with Temporal Lobe Epilepsy is RELN (Reelin), and among its related pathways are GPCRs, Class C Metabotropic glutamate, pheromone and Astrocytic Glutamate-Glutamine Uptake And Metabolism. The drugs phenytoin sodium and phenytoin have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe, brain and amygdala, and related mouse phenotypes are no phenotypic analysis and cellular.

Related Diseases for Temporal Lobe Epilepsy

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Diseases related to Temporal Lobe Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 103)
idRelated DiseaseScoreTop Affiliating Genes
1idiopathic generalized epilepsy29.8BDNF, CALB1, GFAP, LGI1, NPY, PVALB
2personality disorder29.6BDNF, GAD1, HTR1A, PDYN, PVALB, RELN
3schizophrenia28.7BDNF, CALB1, GABBR1, GAD1, GRIK1, HTR1A
4mesial temporal lobe epilepsy with hippocampal sclerosis12.2
5benign familial mesial temporal lobe epilepsy12.1
6infantile-onset mesial temporal lobe epilepsy with severe cognitive regression12.1
7epilepsy, familial temporal lobe, 112.0
8epilepsy, familial temporal lobe, 711.8
9epilepsy, familial temporal lobe, 211.8
10epilepsy, familial temporal lobe, 311.8
11epilepsy, familial temporal lobe, 511.7
12epilepsy, familial temporal lobe, 411.7
13epilepsy, familial temporal lobe, 611.6
14epilepsy, familial temporal lobe, 811.6
15autosomal dominant partial epilepsy with auditory features11.3
16urbach-wiethe disease11.3
17epilepsy11.2
18febrile seizures, familial, 1111.1
19temporal epilepsy, familial11.1
20autosomal dominant epilepsy with auditory features11.1
21mental retardation, anterior maxillary protrusion, and strabismus11.0
22epilepsy, familial focal with variable foci 211.0
23neuronitis10.5
24berardinelli-seip congenital lipodystrophy10.3LGI1, RELN
25status epilepticus10.3
26febrile seizures10.3
27neurogenic thoracic outlet syndrome10.3LGI1, RELN
28cancerophobia10.2CALB1, PVALB
29postencephalitic parkinson disease10.2BDNF, HTR1A, TSPO
30thrombocythemia 310.2SLC1A2, SLC1A3
31cytomegalovirus disease in patients with impaired cell mediated immunity deemed at risk10.2BDNF, PVALB, SLC1A3
32persistent vegetative state10.2CALB1, PVALB, RELN
33encephalitis10.2
34ovarian mucinous adenocarcinoma10.2BDNF, GFAP, SLC1A2
35severe intellectual disability-progressive spastic diplegia syndrome10.2GABBR1, GABBR2
36cerebritis10.1
37chronic conjunctivitis10.1BDNF, GAD1, HTR1A, RELN
38hepatitis d10.1BDNF, HTR1A, NPY, TSPO
39encephalocele10.1
40limbic encephalitis10.1
41brain glioblastoma multiforme10.1BDNF, GAD1, HTR1A, RELN
42siberian tick typhus10.1BDNF, HTR1A, LGI1, PDYN, TSPO
43mucopolysaccharidosis iv10.1BDNF, PVALB, SLC1A2
44meconium aspiration syndrome10.1HTR1A, PDYN
45ovarian cancer10.1GAD1, GFAP, SLC1A2, SLC1A3
46plantar fasciitis10.1GFAP, LGI1, TSPO
47syncope10.0
48preeclampsia/eclampsia 510.0BDNF, GABBR1, GAD1, HTR1A, NPY, PDYN
49parametritis10.0
50mononeuritis multiplex10.0GABBR1, GAD1, LGI1, RELN, SCN1B

Graphical network of the top 20 diseases related to Temporal Lobe Epilepsy:



Diseases related to temporal lobe epilepsy

Symptoms & Phenotypes for Temporal Lobe Epilepsy

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UMLS symptoms related to Temporal Lobe Epilepsy:


seizures, seizures, focal

MGI Mouse Phenotypes related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.3BDNF, GAD1, HTR1A, PDYN, PVALB, SCN1B
2MP:00053848.9BDNF, CASP2, GAD1, GFAP, PVALB, RELN
3MP:00053768.5ACOT7, BDNF, GABBR1, GABBR2, GAD1, GFAP
4MP:00053788.2ACOT7, BDNF, GABBR1, GABBR2, GAD1, GFAP
5MP:00028737.8BDNF, CALB1, GAD1, GFAP, GRIK1, NPY
6MP:00107687.7BDNF, CASP2, GABBR1, GABBR2, GAD1, GFAP
7MP:00053866.8ACOT7, BDNF, CALB1, GABBR1, GABBR2, GAD1
8MP:00036316.6ACOT7, BDNF, CALB1, CASP2, GABBR1, GABBR2

Drugs & Therapeutics for Temporal Lobe Epilepsy

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Drugs for Temporal Lobe Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 70)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CitalopramapprovedPhase 451259729-33-82771
Synonyms:
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
1,3-dihydro[3,4]benzofuran-5-carbonitrile
1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
59729-33-8
AB00513896
AC-12214
AC1L1EFH
AE-641/00603021
Akarin
BPBio1_000929
BRD-A47598013-004-02-0
BSPBio_000843
Bonitrile
C07572
C20H21FN2O
CHEBI:3723
CHEMBL549
CID2771
CPD000465669
Celapram
Celexa
Celius
Ciazil
Cilift
Cipram
Cipramil
Ciprapine
Citabax
Citadur
Citadur (TN)
Citalec
Citalopram (USP/INN)
Citalopram Hydrobromide
Citalopram [Celexa]
Citalopram [INN:BAN]
Citalopram hydrobromide
Citalopramum
Citalopramum [INN-Latin]
 
Citol
Citopam
Citox
Citrol
Cytalopram
D07704
DB00215
Dalsan
EINECS 261-891-1
Elopram
HMS2090O09
HMS2093A14
Humorup
I01-0382
InChI=1/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
L001223
LS-84327
Lopac0_000258
Lu 10-171
Lu-10-171
MolPort-003-666-794
NCGC00015267-07
NCGC00025160-02
Nitalapram
Oropram
Pramcit
Prestwick3_000692
Recital
SAM002589960
ST069372
STL058639
Seropram
Talam
Talohexal
Temperax
UNII-0DHU5B8D6V
Vodelax
Zentius
Zetalo
[3H]Citalopram
citalopram
2
PerphenazineapprovedPhase 49358-39-94748
Synonyms:
.gamma.-[4-(.beta.-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine
1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina
1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina [Italian]
1-(2-Hydroxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine
1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine
1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, trihydrochloride
2-(4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol
2-(4-[3-(2-chloro-10H-Phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol
2-Chloro-10-(3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine
2-Chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine
2-Chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl phenothiazine
2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl]propyl phenothiazine
2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine
2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
2-chloro-10-(3-(4-(2-Hydroxyethyl)piperazin-1-yl)propyl)phenothiazine
2-{4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethanol
2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol
4-(3-(2-Chlorophenothiazin-10-yl)propyl)-1-piperazineethanol
4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol
4-[3-(2-chloro-10H-Phenothiazin-10-yl)propyl]-1-piperazineethanol
58-39-9
AB00052390
AC-12196
AC1L1IVB
AI3-50151
AKOS000664046
Apo-Perphenazine
BAS 00139131
BIDD:GT0150
BPBio1_000188
BRD-K10995081-001-05-5
BSPBio_000170
BSPBio_002376
C07427
C21H26ClN3OS
CAS-58-39-9
CHEBI:8028
CHEMBL567
CID4748
CPD000058180
Chlorperphenazine
Chlorpiprazine
D00503
D010546
DB00850
Decentan
DivK1c_000880
EINECS 200-381-5
EU-0072164
EU-0100930
Emesinal
Etaperazin
Etaperazine
Ethaperazine
Etrafon-A
Etrafon-Forte
F-Mon
F-mon
Fentazin
HMS1568I12
HMS1922M14
HMS2093M15
HMS502L22
HSDB 3379
I06-1508
IDI1_000880
KBio1_000880
KBio2_002090
KBio2_004658
 
KBio2_007226
KBio3_001596
KBioGR_001445
KBioSS_002090
L000919
LS-112185
Lopac-P-6402
Lopac0_000930
MLS000069637
MLS001146929
MolPort-001-727-942
NCGC00015826-01
NCGC00015826-02
NCGC00015826-03
NCGC00015826-06
NCGC00015826-10
NCGC00024092-03
NCGC00024092-04
NCGC00024092-05
NCGC00024092-06
NINDS_000880
NSC 150866
NSC150866
Oprea1_603835
P 6402
P6402_SIGMA
PZC
Perfenazina
Perfenazina [INN-Spanish]
Perfenazina [Italian]
Perfenazine
Perphenan
Perphenazin
Perphenazine (JP15/USP/INN)
Perphenazine [INN:BAN:JAN]
Perphenazine [Trilafon]
Perphenazine maleate
Perphenazinum
Perphenazinum [INN-Latin]
Perphénazine
Prestwick0_000125
Prestwick1_000125
Prestwick2_000125
Prestwick3_000125
Prestwick_536
SAM002264637
SCH-3940
SMR000058180
SPBio_001603
SPBio_002109
SPECTRUM1503934
SR-01000000137-4
STK019818
STOCK1S-21551
Sch 3940
Spectrum2_001602
Spectrum3_000758
Spectrum4_000843
Spectrum5_001493
Spectrum_001610
Thilatazin
Tranquisan
Trifaron
Trilafon
Trilifan
Triphenot
UNII-FTA7XXY4EZ
WLN: T C666 BN ISJ EG B3- AT6N DNTJ D2Q
gamma-(4-(beta-Hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine
nchembio873-comp26
perphenazine
3
AmitriptylineapprovedPhase 411050-48-62160
Synonyms:
10,11-Dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-delta(5),gamma-propylamine
10,11-dihydro-5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,D)cycloheptene
10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene
10,11-dihydro-N,N-Dimethyl-5H-dibenzo(a,D)heptalene-delta(5),gamma-propylamine
17086-03-2 (pamoate (2:1))
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N,N-dimethylpropylamin
3-(10,11-dihydro-5H-Dibenzo(a,D)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
3-(10,11-dihydro-5H-Dibenzo[a,D]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine
3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine
30227-34-0 (maleate (1:1))
5-(3'-Dimethylaminopropylidene)-dibenzo-(a,d)(1,4)-cycloheptadiene
5-(3'-Dimethylaminopropylidene)-dibenzo-[a,d][1,4]-cycloheptadiene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptatriene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(3-Dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene
5-(3-dimethylaminopropylidene)dibenzo[a,d][1,4]-cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(gamma-Dimethylaminopropylidene)-5H-Dibenzo[a,d][1,4]cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,D][1,4]cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,d]10,11-dihydrocycloheptene
5-(gamma-Dimethylaminopropylidine)-5H-dibenzo(a,d)(1,4)cycloheptadiene
50-48-6
549-18-8 (hydrochloride)
AB00514631
AC1L1D20
AKOS000512694
Adepress
Adepril
Amitid
Amitril
Amitriprolidine
Amitriptilina
Amitriptilina [INN-Spanish]
Amitriptilina [Italian]
Amitriptylin
Amitriptylin [German]
Amitriptyline
Amitriptyline (INN)
Amitriptyline HCL
Amitriptyline Hydrochloride
Amitriptyline [INN:BAN]
Amitriptylinum
Amitriptylinum [INN-Latin]
Amitryptiline
Amitryptyline
Amytriptiline
Amytriptylin
BAS 00269727
BIDD:GT0115
BPBio1_000317
BRD-K53737926-003-05-4
BRN 2217885
BSPBio_000287
BSPBio_001836
C06824
CAS-549-18-8
CCRIS 9174
CHEBI:2666
CHEMBL629
CID2160
D07448
DB00321
Damilan
Damilen
Damitriptyline
DivK1c_000766
EINECS 200-041-6
 
Elanil
Elavil
Endep
Flavyl
Hexathane
Horizon
IDI1_000766
KBio1_000766
KBio2_000424
KBio2_002261
KBio2_002992
KBio2_004829
KBio2_005560
KBio2_007397
KBio3_001336
KBio3_002741
KBioGR_000592
KBioGR_002261
KBioSS_000424
KBioSS_002262
L001041
LS-60747
Lantron
Laroxil
Laroxyl
Laroxyl (TN)
Lentizol
Lopac-A-8404
Lopac0_000112
MK 230
MolPort-001-662-651
N 750
NCGC00015095-01
NCGC00015095-02
NCGC00015095-03
NCGC00015095-10
NCGC00024433-04
NINDS_000766
NSC169910
Oprea1_479304
PDSP1_001564
PDSP2_001548
Prestwick0_000074
Prestwick1_000074
Prestwick2_000074
Prestwick3_000074
Proheptadiene
Redomex
Ro 4-1575
SPBio_000082
SPBio_002208
STK525215
STOCK1S-56825
Saroten
Sarotex
Seroten
Spectrum2_000101
Spectrum3_000298
Spectrum4_000146
Spectrum5_000806
Spectrum_000044
Sylvemid
TP0
Triptanol
Triptilin
Triptisol
Tryptanol
Tryptizol
UNII-1806D8D52K
[3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-dimethyl-amine
amitriptyline
cMAP_000001
dAmitriptyline
4
Lidocaineapproved, vet_approvedPhase 41317137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
5
SerotoninPhase 4, Phase 2362750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
6Peripheral Nervous System AgentsPhase 4, Phase 323689
7Serotonin AgentsPhase 4, Phase 23156
8Antidepressive AgentsPhase 42736
9ParasympatholyticsPhase 41085
10Serotonin Uptake InhibitorsPhase 41587
11Psychotropic DrugsPhase 4, Phase 1, Phase 26430
12Neurotransmitter Uptake InhibitorsPhase 43521
13Antiparkinson AgentsPhase 41574
14Antidepressive Agents, Second-GenerationPhase 41311
15Cholinergic AgentsPhase 43992
16Autonomic AgentsPhase 4, Phase 310150
17Cholinergic AntagonistsPhase 41706
18Neurotransmitter AgentsPhase 4, Phase 1, Phase 218340
19Muscarinic AntagonistsPhase 41166
20Central Nervous System DepressantsPhase 4, Phase 1, Phase 213403
21Tranquilizing AgentsPhase 4, Phase 1, Phase 24265
22AnestheticsPhase 4, Phase 39596
23Sodium Channel BlockersPhase 41593
24Diuretics, Potassium SparingPhase 41917
25Antipsychotic AgentsPhase 42401
26Analgesics, Non-NarcoticPhase 46501
27AnalgesicsPhase 411733
28Amitriptyline, perphenazine drug combinationPhase 4110
29Adrenergic AgentsPhase 45352
30Anesthetics, LocalPhase 43492
31Anti-Arrhythmia AgentsPhase 43093
32Antidepressive Agents, TricyclicPhase 4304
33
MentholapprovedPhase 326062216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
34
Dexamethasoneapproved, investigational, vet_approvedPhase 3217150-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
35AnticonvulsantsPhase 3, Phase 2, Phase 12695
36HIV Protease InhibitorsPhase 35470
37Hormone AntagonistsPhase 313180
38Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 313168
39glucocorticoidsPhase 35103
40
protease inhibitorsPhase 35471
Synonyms:
 
protease inhibitors
41HormonesPhase 314415
42AntiemeticsPhase 34022
43Anti-Inflammatory AgentsPhase 310729
44Gastrointestinal AgentsPhase 38402
45Antineoplastic Agents, HormonalPhase 35592
46BB 1101Phase 32171
47Dexamethasone acetatePhase 321711177-87-3
48Dexamethasone 21-phosphatePhase 32171
49PiracetamapprovedPhase 21757491-74-9
50
Valproic Acidapproved, investigationalPhase 1, Phase 232799-66-13121
Synonyms:
(N-C3H7)2CHCOOH
(S)-2-propyl-4-pentanoate
(S)-2-propyl-4-pentanoic acid
2 PP (base)
2-N-Propyl-N-valeric acid
2-Propyl-Pentanoate
2-Propyl-Pentanoic acid
2-Propylpentanoate
2-Propylpentanoic Acid
2-Propylpentanoic acid
2-Propylvaleric Acid
2-Propylvaleric acid
2-n-Propyl-n-valeric acid
2-n-propyl-n-valeric acid
2-propyl-pentanoic acid
2-propylvaleric acid
4-Heptanecarboxylic acid
4-heptanecarboxylic acid
76584-70-8 (hydrochloride salt (2:1))
99-66-1
AC1L1F7T
AC1Q2ULA
AI3-10500
APO-divalproex
Abbott 44090
Acide valproique
Acide valproique [INN-French]
Acide valproique [inn-french]
Acido valproico
Acido valproico [INN-Spanish]
Acido valproico [inn-spanish]
Acidum valproicum
Acidum valproicum [INN-Latin]
Acidum valproicum [inn-latin]
Alti-Valproic
Alti-valproic
Apo-valproic
Apo-valproic syrup
Avugane
BIDD:GT0858
BRN 1750447
Baceca
C07185
CHEBI:39867
CHEMBL109
CID3121
CPD000499581
Convulex
Convulsofin
D00399
DB00313
DOM-divalproex
DOM-valproic
DOM-valproic acid E.C.
DPA
Delepsine
Depacon
Depakene
Depakene (TN)
Depakin
Depakin chrono
Depakine
Depakine chrono
Depakote
Depakote (TM)
Deproic
Di-N-propylacetic acid
Di-N-propylessigsaure
Di-N-propylessigsaure [german]
Di-n-propylacetic acid
Di-n-propylessigsaeure
Di-n-propylessigsaure
Di-n-propylessigsaure [German]
Di-n-propylessigsäure
Dipropyl Acetate
Dipropylacetate
Dipropylacetic acid
DivK1c_000273
Divalproex
Dom-Valproic
Dom-valproate
Dom-valproic acid
Dom-valproic acid syrup
EINECS 202-777-3
Epiject I.V.
Epilex
Epilim
Epival
Epival er
Ergenyl
G2M-777
Gen-divalproex
HMS2089J06
HSDB 3582
I04-0211
InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
KBio1_000273
KBio2_001001
KBio2_002277
KBio2_003569
KBio2_004845
 
KBio2_006137
KBio2_007413
KBio3_002626
KBio3_002757
KBioGR_000871
KBioGR_002277
KBioSS_001001
KBioSS_002278
Kyselina 2-propylvalerova
Kyselina 2-propylvalerova [Czech]
LS-161170
LS-2068
MLS001076682
MLS001335927
MLS001335928
MLS002415770
Med Valproic
Med valproic
MolPort-001-791-895
Mylproin
Myproate
Myproic Acid
Myproic acid
N-DPA
N-Dipropylacetic acid
NCGC00091149-01
NCGC00091149-02
NCGC00091149-03
NCGC00091149-04
NINDS_000273
NSC 93819
NSC93819
Novo-Valproic
Novo-Valproic - ECC
Novo-divalproex
Novo-valproic
Novo-valproic soft gel cap
Nu-Valproic
Nu-valproic
P0823
P6273_SIGMA
PEAC
PHL-valproate
PHL-valproic acid
PHL-valproic acid E.C.
PMS-Divalproex
PMS-Valproic Acid
PMS-valproate
PMS-valproic acid
PMS-valproic acid E.C.
Penta-Valproic
Penta-valproic
Propylvaleric acid
Ratio-Valproic - ECC
S(-)-4-En-valproate
S(-)-4-En-valproic acid
S-2-N-Propyl-4-pentenoate
S-2-N-Propyl-4-pentenoic acid
SAM002564230
SBB065764
SMR000499581
SPBio_000912
Sandoz valproic
Savicol
Semisodium Valproate
Sodium hydrogen divalproate
Spectrum2_000946
Spectrum3_001733
Spectrum4_000376
Spectrum_000521
Sprinkle
Stavzor
UNII-614OI1Z5WI
VALPROIC ACID
VPA
Valcote
Valparin
Valproate
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum seminatricum [Latin]
Valproic Acid, Sodium Salt (2:1)
Valproic acid
Valproic acid (USP)
Valproic acid USP
Valproic acid USP24
Valproic acid [USAN:INN:BAN]
Valproic acid [usan:ban:inn]
Valproinsaeure
Valproinsäure
Vupral
WLN: QVY3 & 3
acide valproïque
acidum valproicum
di-n-propylacetic acid
n-DPA
n-Dipropylacetic acid
nchembio.79-comp4
nchembio815-comp21
valproate
valproic acid
ácido valproico

Interventional clinical trials:

(show top 50)    (show all 52)
idNameStatusNCT IDPhase
1Escitalopram Treatment of Major Depression in Patients With Temporal Lobe EpilepsyCompletedNCT00595699Phase 4
2Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed MigrainesEnrolling by invitationNCT02090998Phase 4
3Early Surgical Intervention to Treat EpilepsyCompletedNCT00040326Phase 3
4Radiosurgery or Open Surgery for Epilepsy TrialActive, not recruitingNCT00860145Phase 3
5Dexamethasone in Herpes Simplex Virus EncephalitisNot yet recruitingNCT03084783Phase 3
6A Multicenter Study of Hippocampal Electrical Stimulation (HS, in Mesial Temporal Lobe EpilepsyTerminatedNCT00717431Phase 3
7Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)CompletedNCT01044758Phase 2
8A Dose Ranging Pilot Study to Assess Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Temporal SeizuresRecruitingNCT02899611Phase 1, Phase 2
9PRX-00023 Therapy in Localization-Related EpilepsyEnrolling by invitationNCT01281956Phase 2
10Buspirone Therapy for Localized EpilepsyTerminatedNCT01496612Phase 2
11Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe EpilepsyCompletedNCT00916266Phase 1
12Efficacy of TDCS for Treating Working Memory Dysfunction and Depression in Temporal Lobe EpilepsyWithdrawnNCT02268578Phase 1
13Controlled Randomized Stimulation Versus Resection (CoRaStiR)Unknown statusNCT00431457
14Emotional Processing and Memory Evaluation in Epilepsy PatientsUnknown statusNCT00486239Early Phase 1
15CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy PatientsCompletedNCT02262156
16Serum Profile of Inflammatory Factors, Immune and Angiogenic in Temporal Lobe EpilepsyCompletedNCT01563627
17Study of [11C]DPA-713 for Temporal Lobe EpilepsyCompletedNCT01793532
18Language and Emotional Function in Patients With Temporal Lobe EpilepsyCompletedNCT00081432
19GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major DepressionCompletedNCT00931619
20Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With EpilepsyCompletedNCT00001672
21Electrical Brain Stimulation to Reduce Epileptic SeizuresCompletedNCT00344877
22Light Scattering Spectroscopy to Determine Brain TumorsCompletedNCT00067418
23Language Mapping in Patients With EpilepsyCompletedNCT00706160
24Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction?CompletedNCT01054599
25Neocortical Epilepsies - Do They Progress?CompletedNCT00610558
26Cartography of Functional and Epileptic Cerebral Areas by Functional MRI and Electroencephalography in Epileptic Patients Before and After SurgeryCompletedNCT03102957
27Arterial Spin Labeling MRI Focal Abnormalities in Refractory EpilepsyCompletedNCT01772654
28MRI in Autosomal Dominant Partial Epilepsy With Auditory FeaturesCompletedNCT00072813
29Serotonin Receptors in Seizure DisordersCompletedNCT00001932
30The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment StudyCompletedNCT01335425
31Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe EpilepsyRecruitingNCT02151175
32Low Frequency Electrical Stimulation of the Fornix in Intractable Mesial Temporal Lobe Epilepsy (MTLE)RecruitingNCT02383407
33Stereotactic Laser Ablation for Temporal Lobe EpilepsyRecruitingNCT02844465
34Treating Deep Seizure Foci With Noninvasive Surface Brain StimulationRecruitingNCT02339376
35Low Frequency TMS for Depression in EpilepsyRecruitingNCT03105700
36Surgery as a Treatment for Medically Intractable EpilepsyRecruitingNCT01273129
37Feasibility Study on LITT for Medical Refractory EpilepsyRecruitingNCT02820740
38Brain P-gp and Inflammation in People With EpilepsyRecruitingNCT01663545
39fMRI Guided TMS Enhancement of Associative Memory NetworksRecruitingNCT02749422
40Longitudinal Monitoring of Cerebral Connectivity 3T MRI in Patients With a Transcient Global AmnesiaRecruitingNCT02796287
41Evaluation and Treatment of Patients With EpilepsyRecruitingNCT00013845
42Single Neurons Responses During Visual Recognition in Epileptic PatientsRecruitingNCT02877576
43Heart Rate Variability (HRV) Analysis in Patients With Nocturnal Epileptic SeizuresRecruitingNCT02469844
44Study of Specimens Obtained During Epilepsy SurgeryRecruitingNCT00025714
45Functional Link Between Hippocampal and Vestibular Systems: a Pilot Study in Epilepsy SurgeryActive, not recruitingNCT01285921
46Controlled Randomized Vagus Nerve Stimulation (VNS) Therapy Versus Resection (CoRaVNStiR)Not yet recruitingNCT02089243
47Subcutaneous EEG in EpilepsyNot yet recruitingNCT02946151
48Application of Diffusion Tensor Imaging and Tractography in Epilepsy SurgeryNot yet recruitingNCT02590419
49COMETE Study : COgnitive Rehabilitation of MEmory in Temporal EpilepsyNot yet recruitingNCT02589470
50Near Death Experience (NDE) and MigraineNot yet recruitingNCT02854930

Search NIH Clinical Center for Temporal Lobe Epilepsy

Inferred drug relations via UMLS68/NDF-RT46:

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Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Temporal Lobe Epilepsy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Temporal Lobe Epilepsy:
Autologous bone marrow-derived mononuclear stem cells for treatment of temporal lobe epilepsy
Embryonic/Adult Cultured Cells Related to Temporal Lobe Epilepsy:
Bone marrow-derived mononuclear cells (family)


Cochrane evidence based reviews: epilepsy, temporal lobe

Genetic Tests for Temporal Lobe Epilepsy

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Anatomical Context for Temporal Lobe Epilepsy

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MalaCards organs/tissues related to Temporal Lobe Epilepsy:

36
Temporal lobe, Brain, Amygdala, Cortex, Bone, Testes, Heart

Publications for Temporal Lobe Epilepsy

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Articles related to Temporal Lobe Epilepsy:

(show top 50)    (show all 980)
idTitleAuthorsYear
1
Genome-Wide DNA Methylation Patterns Analysis of Noncoding RNAs in Temporal Lobe Epilepsy Patients. (28058582)
2017
2
Immunohistochemical study of Metallothionein in patients with temporal lobe epilepsy. (28087193)
2017
3
A Prediction Algorithm for Drug Response in Patients with Mesial Temporal Lobe Epilepsy Based on Clinical and Genetic Information. (28052106)
2017
4
Altered Expression of CXCL13 and CXCR5 in Intractable Temporal Lobe Epilepsy Patients and Pilocarpine-Induced Epileptic Rats. (27873133)
2017
5
Rabies Tracing of Birthdated Dentate Granule Cells in Rat Temporal Lobe Epilepsy. (28470680)
2017
6
Lack of heart rate variability during sleep-related apnea in patients with temporal lobe epilepsy (TLE)-an indirect marker of SUDEP? (28091857)
2017
7
Severe intermittent anxiety attacks. A diagnosis challenge in temporal lobe epilepsy. (28064331)
2017
8
Sex differences in verbal and nonverbal learning before and after temporal lobe epilepsy surgery. (28033547)
2017
9
Preoperative automated fibre quantification predicts postoperative seizure outcome in temporal lobe epilepsy. (28031219)
2017
10
Navigation-assisted trans-inferotemporal cortex selective amygdalohippocampectomy for mesial temporal lobe epilepsy; preserving the temporal stem. (28067149)
2017
11
Smad anchor for receptor activation contributes to seizures in temporal lobe epilepsy. (28035691)
2017
12
Editorial: Limbic Encephalitis: Autoimmune Impact on Inhibitory GABAergic Neuronal Pathways in Temporal Lobe Epilepsy. (27014186)
2016
13
In response: Brain atrophy in seizure-free temporal lobe epilepsy: Implications for predicting pharmacoresistance. (27160803)
2016
14
Naringenin ameliorates kainic acid-induced morphological alterations in the dentate gyrus in a mouse model of temporal lobe epilepsy. (27584687)
2016
15
Effects of Swimming Exercise on Learning and Memory in the Kainate-Lesion Model of Temporal Lobe Epilepsy. (28050361)
2016
16
Prevalence and incidence of drug-resistant mesial temporal lobe epilepsy in the United States. (28034810)
2016
17
Systemic lupus erythematosus manifested as drug-resistant mesial temporal lobe epilepsy. (27592110)
2016
18
Interictal serum brain-derived neurotrophic factor level reflects white matter integrity, epilepsy severity, and cognitive dysfunction in chronic temporal lobe epilepsy. (27152461)
2016
19
Usage of SWI (susceptibility weighted imaging) acquired at 7T for qualitative evaluation of temporal lobe epilepsy patients with histopathological and clinical correlation: An initial pilot study. (27653870)
2016
20
Exploring psychiatric comorbidities and their effects on quality of life in patients with temporal lobe epilepsy and juvenile myoclonic epilepsy. (28025856)
2016
21
Alteration of the alertness-related network in patients with right temporal lobe epilepsy: A resting state fMRI study. (27661438)
2016
22
Interhemispheric functional and structural alterations and their relationships with alertness in unilateral temporal lobe epilepsy. (27160125)
2016
23
Large-scale brain networks are distinctly affected in right and left mesial temporal lobe epilepsy. (27133613)
2016
24
Investigation of hippocampal substructures in focal temporal lobe epilepsy with and without hippocampal sclerosis at 7T. (27564217)
2016
25
An SNP site in pri-miR-124, a brain expressed miRNA gene, no contribution to mesial temporal lobe epilepsy in an Italian sample. (27188998)
2016
26
Social cognition in temporal lobe epilepsy: A systematic review and meta-analysis. (27179192)
2016
27
Does antiepileptic drug withdrawal predispose patients undergoing temporal lobe epilepsy surgery to late onset of psychiatric morbidity? A report of three cases. (27570392)
2016
28
Epilepsy: Tau pathology found in temporal lobe epilepsy. (27562549)
2016
29
Hippocampal malrotation is an anatomic variant and has no clinical significance in MRI-negative temporal lobe epilepsy. (27562507)
2016
30
Brain atrophy in seizure-free temporal lobe epilepsy: Implications for predicting pharmacoresistance. (27160802)
2016
31
Screening LGI1 in a cohort of 26 lateral temporal lobe epilepsy patients with auditory aura from Turkey detects a novel de novo mutation. (26773249)
2016
32
Gray Matter Abnormalities in Temporal Lobe Epilepsy: Relationships with Resting-State Functional Connectivity and Episodic Memory Performance. (27171178)
2016
33
Mesial temporal lobe epilepsy with hippocampal sclerosis as a neuroimmunological disorder. (27170276)
2016
34
The impact of intelligence on memory and executive functions of children with temporal lobe epilepsy: Methodological concerns with clinical relevance. (28089585)
2016
35
Contribution of NRG1 Gene Polymorphisms in Temporal Lobe Epilepsy. (26071373)
2016
36
MBD3 expression and DNA binding patterns are altered in a rat model of temporal lobe epilepsy. (27650712)
2016
37
Lithium therapy in comorbid temporal lobe epilepsy and cycloid psychosis. (28031853)
2016
38
Auditory temporal processing in patients with temporal lobe epilepsy. (27179714)
2016
39
More Severe Extratemporal Damages in Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis Than That With Other Lesions: A Multimodality MRI Study. (26962820)
2016
40
Neuronal autoantibodies in mesial temporal lobe epilepsy with hippocampal sclerosis. (27151964)
2016
41
Long-term drug-resistant temporal lobe epilepsy associated with a mixed ganglioglioma and dysembryoplastic neuroepithelial tumor in an elderly patient. (27127715)
2016
42
Temporal lobe epilepsy associated with GAD autoimmunity. (27638303)
2016
43
Electrophysiological resting-state biomarker for diagnosing mesial temporal lobe epilepsy with hippocampal sclerosis. (28043064)
2016
44
Optimizing memory function in temporal lobe epilepsy. (27164312)
2016
45
Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy. (27162079)
2016
46
Distinctive Structural and Effective Connectivity Changes of Semantic Cognition Network across Left and Right Mesial Temporal Lobe Epilepsy Patients. (28018680)
2016
47
Prognostic factors for seizure outcome in patients with MRI-negative temporal lobe epilepsy: A meta-analysis and systematic review. (27182689)
2016
48
Down-regulation of adenylate kinase 5 in temporal lobe epilepsy patients and rat model. (27288770)
2016
49
Apolipoprotein E I/4 Allele was Associated With Nonlesional Mesial Temporal Lobe Epilepsy in Han Chinese Population. (26945380)
2016
50
White matter abnormalities in patients with temporal lobe epilepsy and amygdala enlargement: Comparison with hippocampal sclerosis and healthy subjects. (27635630)
2016

Variations for Temporal Lobe Epilepsy

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Expression for genes affiliated with Temporal Lobe Epilepsy

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Search GEO for disease gene expression data for Temporal Lobe Epilepsy.

Pathways for genes affiliated with Temporal Lobe Epilepsy

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GO Terms for genes affiliated with Temporal Lobe Epilepsy

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Cellular components related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1G-protein coupled receptor heterodimeric complexGO:003803910.7GABBR1, GABBR2
2axonGO:00304249.9CALB1, GAD1, PVALB, SLC1A2
3synapseGO:00452028.8CALB1, GABBR1, GABBR2, GAD1, GRIK1, LGI1

Biological processes related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1behaviorGO:000761010.7HTR1A, NPY
2D-aspartate importGO:007077910.6SLC1A2, SLC1A3
3regulation of behaviorGO:005079510.6HTR1A, RELN
4positive regulation of synaptic transmissionGO:005080610.6LGI1, SLC1A3
5L-glutamate importGO:005193810.6SLC1A2, SLC1A3
6L-glutamate transmembrane transportGO:008971110.6SLC1A2, SLC1A3
7L-glutamate transportGO:001581310.6SLC1A2, SLC1A3
8gamma-aminobutyric acid biosynthetic processGO:000944910.6GAD1, SLC1A3
9axon guidanceGO:000741110.4BDNF, LGI1, RELN, SCN1B
10response to painGO:004826510.1RELN, TSPO
11ion transportGO:00068119.9GRIK1, SCN1B, SLC1A2, SLC1A3, TSPO
12response to drugGO:00424939.8GAD1, SLC1A2, SLC1A3, TSPO
13chemical synaptic transmissionGO:00072689.3GABBR2, GAD1, GRIK1, NPY, PDYN, SCN1B

Molecular functions related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1G-protein coupled GABA receptor activityGO:000496510.4GABBR1, GABBR2
2glutamate:sodium symporter activityGO:001550110.3SLC1A2, SLC1A3
3glutamate bindingGO:001659510.2GAD1, SLC1A3
4high-affinity glutamate transmembrane transporter activityGO:000531410.2SLC1A2, SLC1A3
5L-glutamate transmembrane transporter activityGO:00053139.9SLC1A2, SLC1A3

Sources for Temporal Lobe Epilepsy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet