MCID: TMP001
MIFTS: 51

Temporal Lobe Epilepsy malady

Categories: Neuronal diseases, Blood diseases

Aliases & Classifications for Temporal Lobe Epilepsy

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Aliases & Descriptions for Temporal Lobe Epilepsy:

Name: Temporal Lobe Epilepsy 35 11 13
Epilepsy, Temporal Lobe 11 39 68
 
Epilepsy Temporal Lobe 50

Classifications:



External Ids:

Disease Ontology11 DOID:3328
MeSH39 D004833

Summaries for Temporal Lobe Epilepsy

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Wikipedia:71 Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent,... more...

MalaCards based summary: Temporal Lobe Epilepsy, also known as epilepsy, temporal lobe, is related to epilepsy and schizophrenia, and has symptoms including seizures, focal and seizures. An important gene associated with Temporal Lobe Epilepsy is RELN (Reelin), and among its related pathways are GPCRs, Class C Metabotropic glutamate, pheromone and Neurotransmitter uptake and Metabolism In Glial Cells. The drugs phenytoin sodium,extended and phenytoin sodium,prompt have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe, brain and bone, and related mouse phenotypes are no phenotypic analysis and cellular.

Related Diseases for Temporal Lobe Epilepsy

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Diseases related to Temporal Lobe Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 108)
idRelated DiseaseScoreTop Affiliating Genes
1epilepsy31.4BDNF, CALB1, GFAP, LGI1, NPY, PVALB
2schizophrenia26.0BDNF, CALB1, GABBR1, GAD1, GRIK1, GRIN1
3mesial temporal lobe epilepsy with hippocampal sclerosis12.2
4benign familial mesial temporal lobe epilepsy12.1
5infantile-onset mesial temporal lobe epilepsy with severe cognitive regression12.1
6epilepsy, familial temporal lobe, 111.9
7epilepsy, familial temporal lobe, 711.8
8epilepsy, familial temporal lobe, 311.8
9epilepsy, familial temporal lobe, 211.8
10epilepsy, familial temporal lobe, 511.7
11epilepsy, familial temporal lobe, 611.6
12epilepsy, familial temporal lobe, 411.6
13epilepsy, familial temporal lobe, 811.6
14urbach-wiethe disease11.3
15autosomal dominant partial epilepsy with auditory features11.3
16temporal epilepsy, familial11.2
17febrile seizures, familial, 1111.1
18autosomal dominant epilepsy with auditory features11.1
19mental retardation, anterior maxillary protrusion, and strabismus11.0
20epilepsy, familial focal, with variable foci 211.0
21autosomal dominant tubulointerstitial kidney disease, muc1-related10.6LGI1, RELN
22peters anomaly-cataract syndrome10.6LGI1, RELN
23neuronitis10.5
24gastroschisis10.5HTR1A, PDYN
25adult central nervous system teratoma10.4CALB1, PVALB
26mixed malaria10.4BDNF, HTR1A, TSPO
27active vestibular meniere's disease10.4BDNF, LGI1
28status epilepticus10.3
29febrile seizures10.3
30transsexualism10.3BDNF, HTR1A, LGI1, PDYN
31ovarian mucinous cystadenocarcinoma10.3BDNF, GFAP, SLC1A2
32glandular cystitis10.3GFAP, SLC1A2, SLC1A3
33o'sullivan-mcleod syndrome10.3CALB1, PVALB, RELN
34iodine hypothyroidism10.3GFAP, NPY
35enthesopathy10.2BDNF, HTR1A, NPY, TSPO
36severe congenital nemaline myopathy10.2GABBR1, GABBR2
37prostatic acinar adenocarcinoma10.2CALB1, GFAP, PVALB
38purpura10.2BDNF, GFAP, HTR1A, NPY
39encephalitis10.2
40spinal stenosis10.2BDNF, GFAP, GRIN1
41cerebritis10.1
42encephalocele10.1
43limbic encephalitis10.1
44intracystic papillary adenoma10.1GFAP, GRIN1
45aplasia of lacrimal and salivary glands10.0SLC1A1, SLC1A3
46syncope10.0
47neurogenic bowel10.0SLC1A1, SLC1A2, TSPO
48parametritis10.0
49idiopathic generalized epilepsy10.0
50systemic lupus erythematosus9.9

Graphical network of the top 20 diseases related to Temporal Lobe Epilepsy:



Diseases related to temporal lobe epilepsy

Symptoms & Phenotypes for Temporal Lobe Epilepsy

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UMLS symptoms related to Temporal Lobe Epilepsy:


seizures, focal, seizures

MGI Mouse Phenotypes related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.9BDNF, GAD1, GRIN1, HTR1A, PDYN, PVALB
2MP:00053848.5BDNF, GAD1, GFAP, GRIN1, PVALB, RELN
3MP:00053918.2BDNF, GFAP, GRIN1, LGI1, RELN, SCN1B
4MP:00053768.1BDNF, GABBR1, GABBR2, GAD1, GFAP, GRIN1
5MP:00053787.9BDNF, GABBR1, GABBR2, GAD1, GFAP, GRIK1
6MP:00028737.9BDNF, CALB1, GAD1, GFAP, GRIK1, GRIN1
7MP:00107687.5BDNF, GABBR1, GABBR2, GAD1, GFAP, GRIN1
8MP:00036316.3BDNF, CALB1, GABBR1, GABBR2, GAD1, GFAP
9MP:00053866.2BDNF, CALB1, GABBR1, GABBR2, GAD1, GFAP

Drugs & Therapeutics for Temporal Lobe Epilepsy

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Drugs for Temporal Lobe Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 56)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CitalopramapprovedPhase 450359729-33-82771
Synonyms:
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
1,3-dihydro[3,4]benzofuran-5-carbonitrile
1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
59729-33-8
AB00513896
AC-12214
AC1L1EFH
AE-641/00603021
Akarin
BPBio1_000929
BRD-A47598013-004-02-0
BSPBio_000843
Bonitrile
C07572
C20H21FN2O
CHEBI:3723
CHEMBL549
CID2771
CPD000465669
Celapram
Celexa
Celius
Ciazil
Cilift
Cipram
Cipramil
Ciprapine
Citabax
Citadur
Citadur (TN)
Citalec
Citalopram (USP/INN)
Citalopram Hydrobromide
Citalopram [Celexa]
Citalopram [INN:BAN]
Citalopram hydrobromide
Citalopramum
Citalopramum [INN-Latin]
 
Citol
Citopam
Citox
Citrol
Cytalopram
D07704
DB00215
Dalsan
EINECS 261-891-1
Elopram
HMS2090O09
HMS2093A14
Humorup
I01-0382
InChI=1/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
L001223
LS-84327
Lopac0_000258
Lu 10-171
Lu-10-171
MolPort-003-666-794
NCGC00015267-07
NCGC00025160-02
Nitalapram
Oropram
Pramcit
Prestwick3_000692
Recital
SAM002589960
ST069372
STL058639
Seropram
Talam
Talohexal
Temperax
UNII-0DHU5B8D6V
Vodelax
Zentius
Zetalo
[3H]Citalopram
citalopram
2
PerphenazineapprovedPhase 49458-39-94748
Synonyms:
.gamma.-[4-(.beta.-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine
1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina
1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina [Italian]
1-(2-Hydroxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine
1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine
1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, trihydrochloride
2-(4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol
2-(4-[3-(2-chloro-10H-Phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol
2-Chloro-10-(3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine
2-Chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine
2-Chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl phenothiazine
2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl]propyl phenothiazine
2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine
2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
2-chloro-10-(3-(4-(2-Hydroxyethyl)piperazin-1-yl)propyl)phenothiazine
2-{4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethanol
2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol
4-(3-(2-Chlorophenothiazin-10-yl)propyl)-1-piperazineethanol
4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol
4-[3-(2-chloro-10H-Phenothiazin-10-yl)propyl]-1-piperazineethanol
58-39-9
AB00052390
AC-12196
AC1L1IVB
AI3-50151
AKOS000664046
Apo-Perphenazine
BAS 00139131
BIDD:GT0150
BPBio1_000188
BRD-K10995081-001-05-5
BSPBio_000170
BSPBio_002376
C07427
C21H26ClN3OS
CAS-58-39-9
CHEBI:8028
CHEMBL567
CID4748
CPD000058180
Chlorperphenazine
Chlorpiprazine
D00503
D010546
DB00850
Decentan
DivK1c_000880
EINECS 200-381-5
EU-0072164
EU-0100930
Emesinal
Etaperazin
Etaperazine
Ethaperazine
Etrafon-A
Etrafon-Forte
F-Mon
F-mon
Fentazin
HMS1568I12
HMS1922M14
HMS2093M15
HMS502L22
HSDB 3379
I06-1508
IDI1_000880
KBio1_000880
KBio2_002090
KBio2_004658
 
KBio2_007226
KBio3_001596
KBioGR_001445
KBioSS_002090
L000919
LS-112185
Lopac-P-6402
Lopac0_000930
MLS000069637
MLS001146929
MolPort-001-727-942
NCGC00015826-01
NCGC00015826-02
NCGC00015826-03
NCGC00015826-06
NCGC00015826-10
NCGC00024092-03
NCGC00024092-04
NCGC00024092-05
NCGC00024092-06
NINDS_000880
NSC 150866
NSC150866
Oprea1_603835
P 6402
P6402_SIGMA
PZC
Perfenazina
Perfenazina [INN-Spanish]
Perfenazina [Italian]
Perfenazine
Perphenan
Perphenazin
Perphenazine (JP15/USP/INN)
Perphenazine [INN:BAN:JAN]
Perphenazine [Trilafon]
Perphenazine maleate
Perphenazinum
Perphenazinum [INN-Latin]
Perphénazine
Prestwick0_000125
Prestwick1_000125
Prestwick2_000125
Prestwick3_000125
Prestwick_536
SAM002264637
SCH-3940
SMR000058180
SPBio_001603
SPBio_002109
SPECTRUM1503934
SR-01000000137-4
STK019818
STOCK1S-21551
Sch 3940
Spectrum2_001602
Spectrum3_000758
Spectrum4_000843
Spectrum5_001493
Spectrum_001610
Thilatazin
Tranquisan
Trifaron
Trilafon
Trilifan
Triphenot
UNII-FTA7XXY4EZ
WLN: T C666 BN ISJ EG B3- AT6N DNTJ D2Q
gamma-(4-(beta-Hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine
nchembio873-comp26
perphenazine
3
AmitriptylineapprovedPhase 410750-48-62160
Synonyms:
10,11-Dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-delta(5),gamma-propylamine
10,11-dihydro-5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,D)cycloheptene
10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene
10,11-dihydro-N,N-Dimethyl-5H-dibenzo(a,D)heptalene-delta(5),gamma-propylamine
17086-03-2 (pamoate (2:1))
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N,N-dimethylpropylamin
3-(10,11-dihydro-5H-Dibenzo(a,D)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
3-(10,11-dihydro-5H-Dibenzo[a,D]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine
3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine
30227-34-0 (maleate (1:1))
5-(3'-Dimethylaminopropylidene)-dibenzo-(a,d)(1,4)-cycloheptadiene
5-(3'-Dimethylaminopropylidene)-dibenzo-[a,d][1,4]-cycloheptadiene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptatriene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(3-Dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene
5-(3-dimethylaminopropylidene)dibenzo[a,d][1,4]-cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(gamma-Dimethylaminopropylidene)-5H-Dibenzo[a,d][1,4]cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,D][1,4]cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,d]10,11-dihydrocycloheptene
5-(gamma-Dimethylaminopropylidine)-5H-dibenzo(a,d)(1,4)cycloheptadiene
50-48-6
549-18-8 (hydrochloride)
AB00514631
AC1L1D20
AKOS000512694
Adepress
Adepril
Amitid
Amitril
Amitriprolidine
Amitriptilina
Amitriptilina [INN-Spanish]
Amitriptilina [Italian]
Amitriptylin
Amitriptylin [German]
Amitriptyline
Amitriptyline (INN)
Amitriptyline HCL
Amitriptyline Hydrochloride
Amitriptyline [INN:BAN]
Amitriptylinum
Amitriptylinum [INN-Latin]
Amitryptiline
Amitryptyline
Amytriptiline
Amytriptylin
BAS 00269727
BIDD:GT0115
BPBio1_000317
BRD-K53737926-003-05-4
BRN 2217885
BSPBio_000287
BSPBio_001836
C06824
CAS-549-18-8
CCRIS 9174
CHEBI:2666
CHEMBL629
CID2160
D07448
DB00321
Damilan
Damilen
Damitriptyline
DivK1c_000766
EINECS 200-041-6
 
Elanil
Elavil
Endep
Flavyl
Hexathane
Horizon
IDI1_000766
KBio1_000766
KBio2_000424
KBio2_002261
KBio2_002992
KBio2_004829
KBio2_005560
KBio2_007397
KBio3_001336
KBio3_002741
KBioGR_000592
KBioGR_002261
KBioSS_000424
KBioSS_002262
L001041
LS-60747
Lantron
Laroxil
Laroxyl
Laroxyl (TN)
Lentizol
Lopac-A-8404
Lopac0_000112
MK 230
MolPort-001-662-651
N 750
NCGC00015095-01
NCGC00015095-02
NCGC00015095-03
NCGC00015095-10
NCGC00024433-04
NINDS_000766
NSC169910
Oprea1_479304
PDSP1_001564
PDSP2_001548
Prestwick0_000074
Prestwick1_000074
Prestwick2_000074
Prestwick3_000074
Proheptadiene
Redomex
Ro 4-1575
SPBio_000082
SPBio_002208
STK525215
STOCK1S-56825
Saroten
Sarotex
Seroten
Spectrum2_000101
Spectrum3_000298
Spectrum4_000146
Spectrum5_000806
Spectrum_000044
Sylvemid
TP0
Triptanol
Triptilin
Triptisol
Tryptanol
Tryptizol
UNII-1806D8D52K
[3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-dimethyl-amine
amitriptyline
cMAP_000001
dAmitriptyline
4
Lidocaineapproved, vet_approvedPhase 41226137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
5
SerotoninPhase 4, Phase 2356650-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
6Psychotropic DrugsPhase 4, Phase 1, Phase 26279
7Serotonin AgentsPhase 4, Phase 23102
8Antidepressive AgentsPhase 42666
9ParasympatholyticsPhase 41050
10Serotonin Uptake InhibitorsPhase 41570
11Peripheral Nervous System AgentsPhase 422776
12Autonomic AgentsPhase 49774
13Antiparkinson AgentsPhase 41527
14Antidepressive Agents, Second-GenerationPhase 41287
15Cholinergic AntagonistsPhase 41658
16Cholinergic AgentsPhase 43846
17Neurotransmitter Uptake InhibitorsPhase 43464
18Neurotransmitter AgentsPhase 4, Phase 2, Phase 117734
19Muscarinic AntagonistsPhase 41134
20Central Nervous System DepressantsPhase 4, Phase 1, Phase 212806
21Tranquilizing AgentsPhase 4, Phase 1, Phase 24164
22AnestheticsPhase 4, Phase 39001
23Sodium Channel BlockersPhase 41515
24Antipsychotic AgentsPhase 42359
25Diuretics, Potassium SparingPhase 41827
26Amitriptyline, perphenazine drug combinationPhase 4107
27Adrenergic AgentsPhase 45140
28AnalgesicsPhase 411287
29Analgesics, Non-NarcoticPhase 46260
30Anti-Arrhythmia AgentsPhase 42969
31Anesthetics, LocalPhase 43272
32Antidepressive Agents, TricyclicPhase 4293
33
MentholapprovedPhase 323532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
34AnticonvulsantsPhase 3, Phase 2, Phase 12620
35PiracetamapprovedPhase 21707491-74-9
36
Valproic Acidapproved, investigationalPhase 1, Phase 232299-66-13121
Synonyms:
(N-C3H7)2CHCOOH
(S)-2-propyl-4-pentanoate
(S)-2-propyl-4-pentanoic acid
2 PP (base)
2-N-Propyl-N-valeric acid
2-Propyl-Pentanoate
2-Propyl-Pentanoic acid
2-Propylpentanoate
2-Propylpentanoic Acid
2-Propylpentanoic acid
2-Propylvaleric Acid
2-Propylvaleric acid
2-n-Propyl-n-valeric acid
2-n-propyl-n-valeric acid
2-propyl-pentanoic acid
2-propylvaleric acid
4-Heptanecarboxylic acid
4-heptanecarboxylic acid
76584-70-8 (hydrochloride salt (2:1))
99-66-1
AC1L1F7T
AC1Q2ULA
AI3-10500
APO-divalproex
Abbott 44090
Acide valproique
Acide valproique [INN-French]
Acide valproique [inn-french]
Acido valproico
Acido valproico [INN-Spanish]
Acido valproico [inn-spanish]
Acidum valproicum
Acidum valproicum [INN-Latin]
Acidum valproicum [inn-latin]
Alti-Valproic
Alti-valproic
Apo-valproic
Apo-valproic syrup
Avugane
BIDD:GT0858
BRN 1750447
Baceca
C07185
CHEBI:39867
CHEMBL109
CID3121
CPD000499581
Convulex
Convulsofin
D00399
DB00313
DOM-divalproex
DOM-valproic
DOM-valproic acid E.C.
DPA
Delepsine
Depacon
Depakene
Depakene (TN)
Depakin
Depakin chrono
Depakine
Depakine chrono
Depakote
Depakote (TM)
Deproic
Di-N-propylacetic acid
Di-N-propylessigsaure
Di-N-propylessigsaure [german]
Di-n-propylacetic acid
Di-n-propylessigsaeure
Di-n-propylessigsaure
Di-n-propylessigsaure [German]
Di-n-propylessigsäure
Dipropyl Acetate
Dipropylacetate
Dipropylacetic acid
DivK1c_000273
Divalproex
Dom-Valproic
Dom-valproate
Dom-valproic acid
Dom-valproic acid syrup
EINECS 202-777-3
Epiject I.V.
Epilex
Epilim
Epival
Epival er
Ergenyl
G2M-777
Gen-divalproex
HMS2089J06
HSDB 3582
I04-0211
InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
KBio1_000273
KBio2_001001
KBio2_002277
KBio2_003569
KBio2_004845
 
KBio2_006137
KBio2_007413
KBio3_002626
KBio3_002757
KBioGR_000871
KBioGR_002277
KBioSS_001001
KBioSS_002278
Kyselina 2-propylvalerova
Kyselina 2-propylvalerova [Czech]
LS-161170
LS-2068
MLS001076682
MLS001335927
MLS001335928
MLS002415770
Med Valproic
Med valproic
MolPort-001-791-895
Mylproin
Myproate
Myproic Acid
Myproic acid
N-DPA
N-Dipropylacetic acid
NCGC00091149-01
NCGC00091149-02
NCGC00091149-03
NCGC00091149-04
NINDS_000273
NSC 93819
NSC93819
Novo-Valproic
Novo-Valproic - ECC
Novo-divalproex
Novo-valproic
Novo-valproic soft gel cap
Nu-Valproic
Nu-valproic
P0823
P6273_SIGMA
PEAC
PHL-valproate
PHL-valproic acid
PHL-valproic acid E.C.
PMS-Divalproex
PMS-Valproic Acid
PMS-valproate
PMS-valproic acid
PMS-valproic acid E.C.
Penta-Valproic
Penta-valproic
Propylvaleric acid
Ratio-Valproic - ECC
S(-)-4-En-valproate
S(-)-4-En-valproic acid
S-2-N-Propyl-4-pentenoate
S-2-N-Propyl-4-pentenoic acid
SAM002564230
SBB065764
SMR000499581
SPBio_000912
Sandoz valproic
Savicol
Semisodium Valproate
Sodium hydrogen divalproate
Spectrum2_000946
Spectrum3_001733
Spectrum4_000376
Spectrum_000521
Sprinkle
Stavzor
UNII-614OI1Z5WI
VALPROIC ACID
VPA
Valcote
Valparin
Valproate
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum seminatricum [Latin]
Valproic Acid, Sodium Salt (2:1)
Valproic acid
Valproic acid (USP)
Valproic acid USP
Valproic acid USP24
Valproic acid [USAN:INN:BAN]
Valproic acid [usan:ban:inn]
Valproinsaeure
Valproinsäure
Vupral
WLN: QVY3 & 3
acide valproïque
acidum valproicum
di-n-propylacetic acid
n-DPA
n-Dipropylacetic acid
nchembio.79-comp4
nchembio815-comp21
valproate
valproic acid
ácido valproico
37
Buspironeapproved, investigationalPhase 24536505-84-72477
Synonyms:
36505-84-7
8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione
8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione
8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione
AB00053432
AC1L1DRN
AKOS002313325
Ansial
Ansiced
Anxiron
Axoren
BAS 00928841
BIDD:GT0519
BPBio1_000547
BPBio1_001403
BRD-K93461745-001-01-5
BRD-K93461745-003-03-7
BRN 0964904
BSPBio_000497
Bespar
Biomol-NT_000108
Buspiron
Buspirona
Buspirona [INN-Spanish]
Buspirone
Buspirone (INN)
Buspirone [INN:BAN]
Buspirone-MDTS
Buspironum
Buspironum [INN-Latin]
Buspisal
C06861
C13H21NO2.C9H14N4
CAS-33386-08-2
CHEBI:3223
CHEMBL49
 
CID2477
D07593
DB00490
DivK1c_000921
EINECS 253-072-2
Gen-Buspirone
Gen-Buspirone (TN)
HMS2090K19
IDI1_000921
KBio1_000921
KBio2_002236
KBio2_004804
KBio2_007372
KBioSS_002236
L001110
LS-22723
Lopac-B-7148
Lopac0_000223
MJ-9022-1
MolPort-002-539-709
N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-1-cyclopentanediacetamide
NCGC00015162-01
NCGC00015162-06
NCGC00016820-01
NCGC00024905-01
NCGC00024905-02
NCGC00024905-03
NINDS_000921
Prestwick0_000369
Prestwick1_000369
Prestwick2_000369
Prestwick3_000369
SPBio_002418
STK086268
STOCK1S-11244
Spectrum_001756
Tocris-0962
UNII-TK65WKS8HL
buspirone
38EtiracetamPhase 2200
39Protective AgentsPhase 27190
40Neuroprotective AgentsPhase 21672
41Nootropic AgentsPhase 2701
42GABA AgentsPhase 1, Phase 21622
43Serotonin 5-HT1 Receptor AgonistsPhase 2203
44Antimanic AgentsPhase 1, Phase 2790
45NaluzotanPhase 23
46Anti-Anxiety AgentsPhase 21816
47
Dopamineapproved375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
48
Sertralineapproved29579617-96-268617
Synonyms:
(+)-Sertraline
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
(1S,4S)-Sertraline
(1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
(1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine
79559-97-0 (Hydrochloride)
79617-96-2
AB00514002
AB1004870
AC-15639
AC1L2A41
AC1Q3O5N
AC1Q3XJU
Apo-Sertraline
BIDD:GT0768
BIDD:PXR0193
BPBio1_001285
BRD-K82036761-003-02-1
BRN 5753709
BSPBio_001167
BSPBio_002698
C07246
C17H17Cl2N
CHEBI:9123
CHEMBL809
CID68617
CP 51974
Cp 51974
D02360
DB01104
DB08567
FT-0081122
HSDB 7037
KBio3_001918
 
KBioGR_001724
LS-94179
Lustral
MLS001195647
MLS002222308
MolPort-002-885-860
NCGC00092386-03
NCGC00092386-04
NCGC00092386-05
NCGC00092386-06
NCGC00092386-07
NCGC00092386-08
NCGC00092386-09
Prestwick3_001014
SMR000596516
SPBio_000385
SRE
Sertralina
Sertralina [Spanish]
Sertraline
Sertraline (INN)
Sertraline Hydrochloride
Sertraline [INN:BAN]
Sertraline [Zoloft]
Sertraline hydrochloride
Sertralinum
Sertralinum [Latin]
Spectrum2_000493
Spectrum3_001079
Spectrum4_001232
Sultamicillin Tosylate
UNII-QUC7NX6WMB
Zoloft
cis-(+)-Sertraline
sertraline
sertraline (Zoloft)
49
Memantineapproved, investigational17619982-08-24054
Synonyms:
1,3-Dimethyl-5-adamantanamine
1-Amino-3,5-dimethyladamantane
19982-08-2
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-adamantylamine
3,5-Dimethyl-1-aminoadamantane
3,5-Dimethyladamantan-1-ylamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
3,5-dimethyladamantan-1-amine
3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
41100-52-1 (Hydrochloride)
51052-62-1
AB00053600
AC1L1HB7
AKOS000113995
BBL000737
BPBio1_001117
BPBio1_001270
BSPBio_001015
Biomol-NT_000209
C13736
CBMicro_020348
CHEBI:152523
CHEMBL807
CID4054
D08174
DB01043
DMAA
DivK1c_000068
EU-0053634
Ebixa
Exiba
Exiba (TN)
HMS500D10
HSDB 7327
IDI1_000068
KBio1_000068
KBio2_001087
KBio2_003655
 
KBio2_006223
KBio3_001926
KBioGR_001543
KBioSS_001087
LS-157051
Lopac0_000861
Memantin
Memantina
Memantina [INN-Spanish]
Memantine
Memantine (INN)
Memantine HCL
Memantine Hydrochloride
Memantine [INN:BAN]
Memantine [INN]
Memantinum
Memantinum [INN-Latin]
MolPort-002-041-858
NCGC00015705-05
NCGC00024782-02
NCGC00024782-03
NINDS_000068
Namenda
Oprea1_480562
Prestwick0_000978
Prestwick1_000978
Prestwick2_000978
Prestwick3_000978
SPBio_001456
SPBio_002926
ST057652
STK520682
Spectrum2_001408
Spectrum3_000923
Spectrum4_001022
Spectrum5_001355
Spectrum_000607
UNII-W8O17SJF3T
ZERO/006024
memantine
50Excitatory Amino Acid Antagonists1282

Interventional clinical trials:

(show all 49)
idNameStatusNCT IDPhase
1Escitalopram Treatment of Major Depression in Patients With Temporal Lobe EpilepsyCompletedNCT00595699Phase 4
2Heart Rate Variability (HRV) Analysis in Patients With Nocturnal Epileptic SeizuresRecruitingNCT02469844Phase 4
3Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed MigrainesEnrolling by invitationNCT02090998Phase 4
4Early Surgical Intervention to Treat EpilepsyCompletedNCT00040326Phase 3
5Radiosurgery or Open Surgery for Epilepsy TrialActive, not recruitingNCT00860145Phase 3
6A Multicenter Study of Hippocampal Electrical Stimulation (HS, in Mesial Temporal Lobe EpilepsyTerminatedNCT00717431Phase 3
7Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)CompletedNCT01044758Phase 2
8PRX-00023 Therapy in Localization-Related EpilepsyRecruitingNCT01281956Phase 2
9A Dose Ranging Pilot Study to Assess Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Temporal SeizuresRecruitingNCT02899611Phase 1, Phase 2
10Buspirone Therapy for Localized EpilepsyTerminatedNCT01496612Phase 2
11Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe EpilepsyCompletedNCT00916266Phase 1
12fMRI Guided TMS Enhancement of Associative Memory NetworksRecruitingNCT02749422Phase 1
13Feasibility Study on LITT for Medical Refractory EpilepsyNot yet recruitingNCT02820740Phase 1
14Efficacy of TDCS for Treating Working Memory Dysfunction and Depression in Temporal Lobe EpilepsyWithdrawnNCT02268578Phase 1
15Controlled Randomized Stimulation Versus Resection (CoRaStiR)Unknown statusNCT00431457
16Emotional Processing and Memory Evaluation in Epilepsy PatientsUnknown statusNCT00486239Early Phase 1
17CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy PatientsCompletedNCT02262156
18Serum Profile of Inflammatory Factors, Immune and Angiogenic in Temporal Lobe EpilepsyCompletedNCT01563627
19Study of [11C]DPA-713 for Temporal Lobe EpilepsyCompletedNCT01793532
20Language and Emotional Function in Patients With Temporal Lobe EpilepsyCompletedNCT00081432
21GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major DepressionCompletedNCT00931619
22Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With EpilepsyCompletedNCT00001672
23Electrical Brain Stimulation to Reduce Epileptic SeizuresCompletedNCT00344877
24Light Scattering Spectroscopy to Determine Brain TumorsCompletedNCT00067418
25Language Mapping in Patients With EpilepsyCompletedNCT00706160
26Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction?CompletedNCT01054599
27Neocortical Epilepsies - Do They Progress?CompletedNCT00610558
28Arterial Spin Labeling MRI Focal Abnormalities in Refractory EpilepsyCompletedNCT01772654
29MRI in Autosomal Dominant Partial Epilepsy With Auditory FeaturesCompletedNCT00072813
30Serotonin Receptors in Seizure DisordersCompletedNCT00001932
31The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment StudyCompletedNCT01335425
32Low-intensity Focused Ultrasound Pulsation (LIFUP) for Treatment of Temporal Lobe EpilepsyRecruitingNCT02151175
33Low Frequency Electrical Stimulation of the Fornix in Intractable Mesial Temporal Lobe Epilepsy (MTLE)RecruitingNCT02383407
34Stereotactic Laser Ablation for Temporal Lobe EpilepsyRecruitingNCT02844465
35Treating Deep Seizure Foci With Noninvasive Surface Brain StimulationRecruitingNCT02339376
36Surgery as a Treatment for Medically Intractable EpilepsyRecruitingNCT01273129
37Brain P-gp and Inflammation in People With EpilepsyRecruitingNCT01663545
38Longitudinal Monitoring of Cerebral Connectivity 3T MRI in Patients With a Transcient Global AmnesiaRecruitingNCT02796287
39Evaluation and Treatment of Patients With EpilepsyRecruitingNCT00013845
40Single Neurons Responses During Visual Recognition in Epileptic PatientsRecruitingNCT02877576
41Study of Specimens Obtained During Epilepsy SurgeryRecruitingNCT00025714
42Functional Link Between Hippocampal and Vestibular Systems: a Pilot Study in Epilepsy SurgeryActive, not recruitingNCT01285921
43The Utility of NIOM During LITT for Refractory MTLENot yet recruitingNCT02913742
44Controlled Randomized Vagus Nerve Stimulation (VNS) Therapy Versus Resection (CoRaVNStiR)Not yet recruitingNCT02089243
45Subcutaneous EEG in EpilepsyNot yet recruitingNCT02946151
46Application of Diffusion Tensor Imaging and Tractography in Epilepsy SurgeryNot yet recruitingNCT02590419
47COMETE Study : COgnitive Rehabilitation of MEmory in Temporal EpilepsyNot yet recruitingNCT02589470
48Near Death Experience (NDE) and MigraineNot yet recruitingNCT02854930
49Efficacy and Safety of the Use of Memantine for Preserving Cognition in Adult Patients With EpilepsyWithdrawnNCT00986115

Search NIH Clinical Center for Temporal Lobe Epilepsy

Inferred drug relations via UMLS68/NDF-RT46:

Show with subtypes

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Temporal Lobe Epilepsy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Temporal Lobe Epilepsy:
Autologous bone marrow-derived mononuclear stem cells for treatment of temporal lobe epilepsy
Embryonic/Adult Cultured Cells Related to Temporal Lobe Epilepsy:
Bone marrow-derived mononuclear cells (family)


Cochrane evidence based reviews: epilepsy, temporal lobe

Genetic Tests for Temporal Lobe Epilepsy

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Anatomical Context for Temporal Lobe Epilepsy

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MalaCards organs/tissues related to Temporal Lobe Epilepsy:

36
Temporal lobe, Brain, Bone, Amygdala, Cortex, Heart, Testes

Publications for Temporal Lobe Epilepsy

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Articles related to Temporal Lobe Epilepsy:

(show top 50)    (show all 976)
idTitleAuthorsYear
1
Smad anchor for receptor activation contributes to seizures in temporal lobe epilepsy. (28035691)
2017
2
Preoperative automated fibre quantification predicts postoperative seizure outcome in temporal lobe epilepsy. (28031219)
2017
3
Genome-Wide DNA Methylation Patterns Analysis of Noncoding RNAs in Temporal Lobe Epilepsy Patients. (28058582)
2017
4
Immunohistochemical study of Metallothionein in patients with temporal lobe epilepsy. (28087193)
2017
5
Lack of heart rate variability during sleep-related apnea in patients with temporal lobe epilepsy (TLE)-an indirect marker of SUDEP? (28091857)
2017
6
A Prediction Algorithm for Drug Response in Patients with Mesial Temporal Lobe Epilepsy Based on Clinical and Genetic Information. (28052106)
2017
7
Sex differences in verbal and nonverbal learning before and after temporal lobe epilepsy surgery. (28033547)
2017
8
Navigation-assisted trans-inferotemporal cortex selective amygdalohippocampectomy for mesial temporal lobe epilepsy; preserving the temporal stem. (28067149)
2017
9
Severe intermittent anxiety attacks. A diagnosis challenge in temporal lobe epilepsy. (28064331)
2017
10
Pharmacological modulation in mesial temporal lobe epilepsy: Current status and future perspectives. (27659220)
2016
11
Decision-making in patients with temporal lobe epilepsy: Delay gratification ability is not impaired in patients with hippocampal sclerosis. (27206236)
2016
12
An SNP site in pri-miR-124, a brain expressed miRNA gene, no contribution to mesial temporal lobe epilepsy in an Italian sample. (27188998)
2016
13
Altered microRNA profiles in plasma exosomes from mesial temporal lobe epilepsy with hippocampal sclerosis. (27926529)
2016
14
Age of onset of mesial temporal lobe epilepsy with hippocampal sclerosis: the effect of apolipoprotein E and febrile seizures. (27875923)
2016
15
Lithium therapy in comorbid temporal lobe epilepsy and cycloid psychosis. (28031853)
2016
16
Adenosine A2A receptor and ecto-5'-nucleotidase/CD73 are upregulated in hippocampal astrocytes of human patients with mesial temporal lobe epilepsy (MTLE). (27650530)
2016
17
Interhemispheric functional and structural alterations and their relationships with alertness in unilateral temporal lobe epilepsy. (27160125)
2016
18
Apolipoprotein E I/4 Allele was Associated With Nonlesional Mesial Temporal Lobe Epilepsy in Han Chinese Population. (26945380)
2016
19
Neuronal autoantibodies in mesial temporal lobe epilepsy with hippocampal sclerosis. (27151964)
2016
20
Long-term Follow-up of Ictal Asystole in Temporal Lobe Epilepsy: Is Permanent Pacemaker Therapy Needed? (27172926)
2016
21
Epilepsy surgery in a liver-transplanted girl with temporal lobe epilepsy and hippocampal sclerosis following PRES with status epilepticus. (27133780)
2016
22
Mesial temporal lobe epilepsy with hippocampal sclerosis as a neuroimmunological disorder. (27170276)
2016
23
Hippocampal atrophy on MRI is predictive of histopathological patterns and surgical prognosis in mesial temporal lobe epilepsy with hippocampal sclerosis. (27842262)
2016
24
Naringenin ameliorates kainic acid-induced morphological alterations in the dentate gyrus in a mouse model of temporal lobe epilepsy. (27584687)
2016
25
Usage of SWI (susceptibility weighted imaging) acquired at 7T for qualitative evaluation of temporal lobe epilepsy patients with histopathological and clinical correlation: An initial pilot study. (27653870)
2016
26
Optimizing memory function in temporal lobe epilepsy. (27164312)
2016
27
Remote preoperative tonic-clonic seizures do not influence outcome after surgery for temporal lobe epilepsy. (27653919)
2016
28
Investigation of hippocampal substructures in focal temporal lobe epilepsy with and without hippocampal sclerosis at 7T. (27564217)
2016
29
Alteration of the alertness-related network in patients with right temporal lobe epilepsy: A resting state fMRI study. (27661438)
2016
30
Hippocampal malrotation is an anatomic variant and has no clinical significance in MRI-negative temporal lobe epilepsy. (27562507)
2016
31
Metabotropic glutamate receptor 2/3 density and its relation to the hippocampal neuropathology in a model of temporal lobe epilepsy in rats. (27565411)
2016
32
Long-term outcome of mild mesial temporal lobe epilepsy: A prospective longitudinal cohort study. (27164663)
2016
33
Gray Matter Abnormalities in Temporal Lobe Epilepsy: Relationships with Resting-State Functional Connectivity and Episodic Memory Performance. (27171178)
2016
34
In response: Brain atrophy in seizure-free temporal lobe epilepsy: Implications for predicting pharmacoresistance. (27160803)
2016
35
Increased expression of BDNF transcript with exon VI in hippocampi of patients with pharmaco-resistant temporal lobe epilepsy. (26621122)
2016
36
Interictal serum brain-derived neurotrophic factor level reflects white matter integrity, epilepsy severity, and cognitive dysfunction in chronic temporal lobe epilepsy. (27152461)
2016
37
Exploring psychiatric comorbidities and their effects on quality of life in patients with temporal lobe epilepsy and juvenile myoclonic epilepsy. (28025856)
2016
38
Increased expression of interleukin 17 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy. (27609289)
2016
39
Cognitive Function and Heat Shock Protein 70 in Children With Temporal Lobe Epilepsy. (27664194)
2016
40
MBD3 expression and DNA binding patterns are altered in a rat model of temporal lobe epilepsy. (27650712)
2016
41
The impact of intelligence on memory and executive functions of children with temporal lobe epilepsy: Methodological concerns with clinical relevance. (28089585)
2016
42
Cognitive changes in people with temporal lobe epilepsy over a 13-year period. (27585986)
2016
43
Small temporal pole encephalocele: A hidden cause of "normal" MRI temporal lobe epilepsy. (27020612)
2016
44
Distinctive Structural and Effective Connectivity Changes of Semantic Cognition Network across Left and Right Mesial Temporal Lobe Epilepsy Patients. (28018680)
2016
45
The evolving utility of diffusion tensor tractography in the surgical management of temporal lobe epilepsy: a review. (27566714)
2016
46
Systemic lupus erythematosus manifested as drug-resistant mesial temporal lobe epilepsy. (27592110)
2016
47
MRI-guided laser interstitial thermal therapy for treatment of medically refractory non-lesional mesial temporal lobe epilepsy: Outcomes, complications, and current limitations: A review. (28024732)
2016
48
Electrophysiological resting-state biomarker for diagnosing mesial temporal lobe epilepsy with hippocampal sclerosis. (28043064)
2016
49
The effect of transcranial direct current stimulation on seizure frequency of patients with mesial temporal lobe epilepsy with hippocampal sclerosis. (27450765)
2016
50
Brain atrophy in seizure-free temporal lobe epilepsy: Implications for predicting pharmacoresistance. (27160802)
2016

Variations for Temporal Lobe Epilepsy

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Expression for genes affiliated with Temporal Lobe Epilepsy

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Search GEO for disease gene expression data for Temporal Lobe Epilepsy.

Pathways for genes affiliated with Temporal Lobe Epilepsy

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Pathways related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

(show all 16)
idSuper pathwaysScoreTop Affiliating Genes
110.0GABBR1, GABBR2
2
Show member pathways
10.0SLC1A2, SLC1A3
39.7GABBR1, GABBR2, GAD1
4
Show member pathways
9.7BDNF, GRIN1, PDYN
5
Show member pathways
9.7GABBR1, GABBR2, HTR1A
69.5CALB1, HTR1A, TSPO
79.5BDNF, GFAP, GRIN1, PDYN
89.5BDNF, GAD1, GFAP, SLC1A3
9
Show member pathways
9.4GAD1, SLC1A1, SLC1A2, SLC1A3
109.3BDNF, GRIN1, HTR1A, SLC1A3
11
Show member pathways
9.3GRIN1, SLC1A1, SLC1A2, SLC1A3
12
Show member pathways
8.9BDNF, GABBR1, GABBR2, GRIN1, HTR1A, NPY
13
Show member pathways
8.5GABBR1, GABBR2, GRIK1, GRIN1, HTR1A, NPY
14
Show member pathways
8.3GABBR1, GABBR2, GAD1, GRIK1, GRIN1, SLC1A1
15
Show member pathways
8.0GABBR1, GABBR2, GAD1, GRIK1, GRIN1, HTR1A
167.1CALB1, GABBR1, GABBR2, GAD1, GFAP, GRIN1

GO Terms for genes affiliated with Temporal Lobe Epilepsy

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Cellular components related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1axolemmaGO:003067310.9GABBR1, SLC1A2
2G-protein coupled receptor heterodimeric complexGO:003803910.8GABBR1, GABBR2
3dendritic spineGO:004319710.4GABBR1, GRIN1, SLC1A3
4synaptic vesicleGO:000802110.2GABBR1, GRIN1, SV2B
5postsynaptic membraneGO:00452119.9GABBR1, GABBR2, GRIK1, GRIN1
6neuron projectionGO:00430059.9CALB1, GABBR2, GRIN1, SLC1A3
7cell junctionGO:00300549.8GABBR1, GABBR2, GRIK1, GRIN1, LGI1, SV2B
8neuronal cell bodyGO:00430259.3CALB1, GABBR1, GRIN1, PDYN, PVALB, SLC1A3
9terminal boutonGO:00431959.2CALB1, GRIN1, PVALB
10plasma membraneGO:00058867.8GABBR1, GABBR2, GAD1, GRIK1, GRIN1, HTR1A

Biological processes related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of adenylate cyclase activityGO:000719410.7GABBR1, GABBR2
2gamma-aminobutyric acid biosynthetic processGO:000944910.6GAD1, SLC1A3
3response to painGO:004826510.6RELN, TSPO
4positive regulation of glial cell proliferationGO:006025210.6GFAP, TSPO
5regulation of behaviorGO:005079510.5HTR1A, RELN
6ionotropic glutamate receptor signaling pathwayGO:003523510.5GRIK1, GRIN1
7positive regulation of synaptic transmissionGO:005080610.5LGI1, SLC1A3
8positive regulation of excitatory postsynaptic potentialGO:200046310.5GRIN1, RELN
9cerebral cortex developmentGO:002198710.5GRIN1, NPY, RELN
10D-aspartate importGO:007077910.4SLC1A1, SLC1A2, SLC1A3
11glutamate secretionGO:001404710.4SLC1A1, SLC1A2, SLC1A3
12L-glutamate importGO:005193810.3SLC1A1, SLC1A2, SLC1A3
13L-glutamate transmembrane transportGO:008971110.3SLC1A1, SLC1A2, SLC1A3
14L-glutamate transportGO:001581310.3SLC1A1, SLC1A2, SLC1A3
15axon guidanceGO:000741110.3BDNF, LGI1, RELN, SCN1B
16nervous system developmentGO:000739910.2BDNF, GRIK1, LGI1, SLC1A2
17long-term memoryGO:000761610.2CALB1, GRIN1, RELN
18ion transportGO:000681110.1SLC1A1, SLC1A2, SLC1A3, TSPO
19response to woundingGO:00096119.8GFAP, SLC1A2, SLC1A3
20chemical synaptic transmissionGO:00072688.3GABBR2, GAD1, GRIK1, GRIN1, NPY, PDYN

Molecular functions related to Temporal Lobe Epilepsy according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1G-protein coupled GABA receptor activityGO:000496510.4GABBR1, GABBR2
2glutamate:sodium symporter activityGO:001550110.3SLC1A1, SLC1A2
3extracellular-glutamate-gated ion channel activityGO:000523410.3GRIK1, GRIN1
4amino acid transmembrane transporter activityGO:001517110.1SLC1A1, SLC1A2, SLC1A3
5high-affinity glutamate transmembrane transporter activityGO:00053149.9SLC1A1, SLC1A2, SLC1A3
6L-glutamate transmembrane transporter activityGO:00053139.7SLC1A1, SLC1A2, SLC1A3
7glutamate bindingGO:00165959.5GAD1, GRIN1, SLC1A1, SLC1A3

Sources for Temporal Lobe Epilepsy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet