Aliases & Classifications for Tendinopathy

Aliases & Descriptions for Tendinopathy:

Name: Tendinopathy 39 38 69

Summaries for Tendinopathy

MalaCards based summary : Tendinopathy is related to tendinitis and tendinosis, and has symptoms including muscle cramp, muscle rigidity and muscle spasticity. An important gene associated with Tendinopathy is COL5A1 (Collagen Type V Alpha 1 Chain), and among its related pathways/superpathways are Degradation of the extracellular matrix and Matrix Metalloproteinases. The drugs Ibuprofen and Hyaluronic acid have been mentioned in the context of this disorder. Affiliated tissues include testes, bone and endothelial, and related phenotypes are homeostasis/metabolism and neoplasm

Wikipedia : 71 Tendinopathy refers to a disease of a tendon. The clinical presentation includes tenderness on palpation... more...

Related Diseases for Tendinopathy

Diseases related to Tendinopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
id Related Disease Score Top Affiliating Genes
1 tendinitis 11.7
2 tendinosis 11.3
3 cole disease 10.9
4 de quervain disease 10.8
5 patellar tendinitis 10.8
6 senile atrophy of choroid 10.1 MMP1 NOS2
7 acquired thrombocytopenia 10.1 MMP1 NOS2
8 hereditary night blindness 10.0 DCN MMP1
9 epicondylitis 10.0
10 acth-independent macronodular adrenal hyperplasia 10.0 DCN ENPP1
11 lubani-al saleh-teebi syndrome 10.0 DCN NOS2
12 adult-onset still's disease 10.0 MMP8 VCAN
13 mosaic variegated aneuploidy syndrome 2 10.0 MMP1 MMP8
14 peripheral vascular disease 10.0 MMP1 MMP8
15 bursitis 10.0
16 pasteurellosis 10.0 MMP1 MMP8
17 kashin-beck disease 10.0 DCN MMP1
18 vitreoretinopathy, neovascular inflammatory 10.0 MMP1 MMP8
19 germ cell and embryonal cancer 9.9 DCN MMP1
20 enthesopathy 9.9
21 neuronitis 9.9
22 autosomal recessive type iv ehlers-danlos syndrome 9.9 MMP1 MMP8
23 cholera 9.9 MMP1 MMP8
24 onychocytic matricoma 9.9 DCN MMP1 VCAN
25 mixed ductal-endocrine carcinoma 9.9 MMP1 MMP8
26 endotheliitis 9.9
27 fasciitis 9.9
28 chronic pain 9.9
29 renal oncocytoma 9.8 MMP1 MMP8
30 obesity 9.8
31 plantar fasciitis 9.8
32 hypoxia 9.8
33 optic nerve neoplasm 9.7 MMP1 MMP8
34 gout 9.6
35 shoulder impingement syndrome 9.6
36 giant cell tumor 9.6
37 pseudoachondroplasia 9.6
38 myopathy 9.6
39 osteoarthritis 9.6
40 spinal cord injury 9.6
41 tenosynovitis 9.6
42 parotitis 9.6
43 osteochondroma 9.6
44 cardiovascular disease risk factor ) 9.6
45 lyme disease 9.6
46 multiple epiphyseal dysplasia 9.6
47 chronic diarrhea due to guanylate cyclase 2c overactivity 9.0 COL5A1 DCN ENPP1 MMP1 MMP8 NOS2

Graphical network of the top 20 diseases related to Tendinopathy:



Diseases related to Tendinopathy

Symptoms & Phenotypes for Tendinopathy

UMLS symptoms related to Tendinopathy:


muscle cramp, muscle rigidity, muscle spasticity, muscle weakness, myalgia

MGI Mouse Phenotypes related to Tendinopathy:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.43 DCN ENPP1 MMP1 MMP8 NOS2 VCAN
2 neoplasm MP:0002006 8.92 DCN MMP1 MMP8 NOS2

Drugs & Therapeutics for Tendinopathy

Drugs for Tendinopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 193)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ibuprofen Approved Phase 4,Phase 3,Phase 2 15687-27-1 3672
2
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 2,Phase 3,Early Phase 1 9004-61-9 53477741 24759
3
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
4
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3 137-58-6 3676
5
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 124-94-7 31307
6
Cortisone acetate Approved Phase 4 1950-04-4, 50-04-4 5745
7
Polidocanol Approved Phase 4,Phase 2 9002-92-0
8
Epinephrine Approved, Vet_approved Phase 4,Phase 3 51-43-4 5816
9
Diclofenac Approved, Vet_approved Phase 4,Phase 2,Phase 3 15307-86-5 3033
10
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
11
Etanercept Approved, Investigational Phase 4 185243-69-0
12
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
13
Bupivacaine Approved, Investigational Phase 4,Phase 3 2180-92-9, 38396-39-3 2474
14
Etoricoxib Approved, Investigational Phase 4,Phase 3 202409-33-4 123619
15
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
16
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3 50-02-2 5743
17
Ketorolac Approved Phase 4,Phase 3 74103-06-3, 66635-83-4 3826
18
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
19
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 2 76-42-6 5284603
20
Guaifenesin Approved, Vet_approved Phase 4 93-14-1 3516
21
Cortisone Phase 4 53-06-5 222786
22 triamcinolone acetonide Phase 4,Phase 2,Phase 3
23 Betamethasone Valerate Phase 4,Phase 3 2152-44-5
24 Analgesics Phase 4,Phase 3,Phase 2
25 glucocorticoids Phase 4,Phase 3,Phase 2
26 Adjuvants, Immunologic Phase 4,Phase 2,Phase 3,Early Phase 1
27 Sodium Channel Blockers Phase 4,Phase 2,Phase 3
28 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2
29 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
30 Hormone Antagonists Phase 4,Phase 3,Phase 2
31 Anesthetics Phase 4,Phase 2,Phase 3
32 Triamcinolone diacetate Phase 4,Phase 2,Phase 3
33 Triamcinolone hexacetonide Phase 4,Phase 2,Phase 3
34 Hormones Phase 4,Phase 3,Phase 2
35 Diuretics, Potassium Sparing Phase 4,Phase 2,Phase 3
36 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
37 Anesthetics, Local Phase 4,Phase 2,Phase 3
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
39 Viscosupplements Phase 4,Phase 2,Phase 3,Early Phase 1
40 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2
41 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3
42 Anti-Asthmatic Agents Phase 4,Phase 3
43 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Early Phase 1
44 Protective Agents Phase 4,Phase 2,Phase 3,Early Phase 1
45 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
46 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2
47 Respiratory System Agents Phase 4,Phase 3
48 Antirheumatic Agents Phase 4,Phase 3,Phase 2
49 Betamethasone benzoate Phase 4,Phase 3
50 Betamethasone sodium phosphate Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 192)
id Name Status NCT ID Phase
1 A Randomized Trial to Evaluate the Effectiveness of Transferring the Flexor Hallucis Longus Tendon Unknown status NCT01341509 Phase 4
2 "NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes" Completed NCT00792376 Phase 4
3 The Value of Platelet-Rich Plasma in Chronic Midportion Achilles Tendinopathy: a Double-blind Randomized Clinical Trial Completed NCT00761423 Phase 4
4 The Efficacy of Polidocanol Injections as a Treatment of Chronic Achilles. Tendinopathy Completed NCT00377910 Phase 4
5 Shockwave Therapy of Chronic Achilles Tendinopathy Completed NCT00958620 Phase 4
6 Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to Corticosteroids Intrabursal Injection Completed NCT01652495 Phase 4
7 Achilles Tendinosis Study; Comparison of Radiofrequency to Surgical MicroDebridement Completed NCT00534781 Phase 4
8 Study Evaluating Etanercept for the Treatment of Refractory Heel Enthesitis in Spondylarthropathy Completed NCT00420303 Phase 4
9 Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer Completed NCT00950053 Phase 4
10 A Study of the Use of the Madrid Ultrasound Scoring System in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With Spondyloarthritis Completed NCT02960035 Phase 4
11 Bupivacaine Versus Lidocaine Local Anesthesia Completed NCT01751347 Phase 4
12 Achilles Tendinopathy Treated With Training and Injections Recruiting NCT02580630 Phase 4
13 Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy Recruiting NCT02978833 Phase 4
14 High-Volume Image-Guided Injection in Chronic Midportion Achilles Tendinopathy Recruiting NCT02996409 Phase 4
15 Celestone Versus Ketorolac Injection for the Treatment of DeQuervains Tenosyovitis Recruiting NCT02604537 Phase 4
16 Functional Improvement and UTC of the Achilles Tendon After Sodium Hyaluronate Injection for Plantaris Syndrome Recruiting NCT03077009 Phase 4
17 Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection Recruiting NCT02403856 Phase 4
18 Ultrasound-guided Injection for DeQuervain's Recruiting NCT02038634 Phase 4
19 Post-operative Analgesia in Elective, Soft-tissue Hand Surgery Enrolling by invitation NCT02029235 Phase 4
20 Effectiveness of Cortisone Injection and Splinting for Trigger Finger Not yet recruiting NCT03156829 Phase 4
21 Pain With Trigger Finger Injection: A Comparison of Steroid Alone Versus Steroid/Lidocaine Mixture Terminated NCT02421419 Phase 4
22 Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis Withdrawn NCT00420875 Phase 4
23 Effect of Plasma Rich in Growth Factors in Rotator Cuff Tendinopathy Unknown status NCT01915979 Phase 3
24 Treatment for Achilles Tendinopathy Unknown status NCT00835939 Phase 2, Phase 3
25 Eccentric Training With or Without Elbow Brace for Epicondylitis Unknown status NCT01273688 Phase 3
26 VIBration Training in EpicondylitiS Unknown status NCT01269879 Phase 3
27 Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff Tendinosis Unknown status NCT00196573 Phase 3
28 Epidemiology of Incidents and Accidents in Sport. Influence of Moisture. Unknown status NCT02346786 Phase 3
29 Efficacy and Safety of Salonsip Compared to Sabiá Plaster Unknown status NCT00970658 Phase 3
30 Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel Unknown status NCT01373697 Phase 3
31 Radial Extracorporeal Shock Wave Therapy (rESWT) Treatment of Subacromial Shoulder Pain Unknown status NCT01441830 Phase 3
32 To Evaluate the Efficacy and Safety Aliviador Compared to Gelol in Patients With Contusions, Sprains, Trauma and Muscle Injury. Unknown status NCT01097798 Phase 3
33 Autologous Tenocyte Implantation in Patients With Chronic Achilles Tendinopathy Completed NCT01343836 Phase 2, Phase 3
34 MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder Completed NCT01161615 Phase 3
35 Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis Completed NCT00352625 Phase 3
36 A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis Completed NCT01166282 Phase 3
37 Safety & Efficacy Study of MRX-7EAT Patch in the Treatment of Pain of the Shoulder Completed NCT01506154 Phase 3
38 Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3
39 Platelet Rich Plasma (PRP) in Chronic Epicondylitis Recruiting NCT01945528 Phase 3
40 Analgesic Benefit of PECS Blocks for Biceps Tenodesis Shoulder Surgery Recruiting NCT02741713 Phase 3
41 Study of Efficacy and Safety of Secukinumab in Psoriatic Arthritis and Axial Spondyloarthritis Patients With Active Enthesitis Including One Achilles Tendon Site Recruiting NCT02771210 Phase 3
42 Efficacy of Ultrasound Guided Hyaluronic Injection in Treatment of Trigger Finger Recruiting NCT03131882 Phase 2, Phase 3
43 Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders Recruiting NCT02266433 Phase 3
44 Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Active, not recruiting NCT01371656 Phase 3
45 Ultrasound Guided A1 Pulley Release For The Treatment of Trigger Finger Active, not recruiting NCT02830672 Phase 2, Phase 3
46 A Dynamic Elastic Garment (DEG) in Patients With Rotator Cuff Tendinopathy Not yet recruiting NCT03032432 Phase 3
47 Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy? Not yet recruiting NCT02967640 Phase 2, Phase 3
48 Glenohumeral Re-centering During Closed Kinetic Chain for Shoulder Physiotherapy. A Prospective and Randomized Study. Not yet recruiting NCT02874105 Phase 3
49 Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis Terminated NCT00426985 Phase 3
50 Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder Terminated NCT00876317 Phase 3

Search NIH Clinical Center for Tendinopathy

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tendinopathy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tendinopathy:
Autologous tenocyte implantation for damaged tendons
Embryonic/Adult Cultured Cells Related to Tendinopathy:
Tenocytes PMIDs: 24068695 23314880

Genetic Tests for Tendinopathy

Anatomical Context for Tendinopathy

MalaCards organs/tissues related to Tendinopathy:

39
Testes, Bone, Endothelial, Lung, Bone Marrow, Whole Blood, Spinal Cord

Publications for Tendinopathy

Articles related to Tendinopathy:

(show top 50) (show all 637)
id Title Authors Year
1
Revision Surgery for Failed Patellar Tendinopathy Exploration. ( 28045872 )
2017
2
Extensor tendinopathy of the elbow assessed with sonoelastography: histologic correlation. ( 28058481 )
2017
3
High-molecular-weight hyaluronic acid attenuated matrix metalloproteinase-1 and -3 expression via CD44 in tendinopathy. ( 28091588 )
2017
4
Calcific tendinopathy of the shoulder with intraosseous extension: outcomes of ultrasound-guided percutaneous irrigation. ( 27909786 )
2017
5
Acute rotator cuff tendinopathy: does ice, low load isometric exercise, or a combination of the two produce an analgaesic effect? ( 27166286 )
2016
6
Ultrasound-Guided Percutaneous Irrigation of Calcific Tendinopathy. ( 28002862 )
2016
7
Exercise and load modification versus corticosteroid injection versus 'wait and see' for persistent gluteus medius/minimus tendinopathy (the LEAP trial): a protocol for a randomised clinical trial. ( 27139495 )
2016
8
Can ultrasound imaging predict the development of Achilles and patellar tendinopathy? A systematic review and meta-analysis. ( 27633025 )
2016
9
Acute Calcific Bursitis After Ultrasound-Guided Percutaneous Barbotage of Rotator Cuff Calcific Tendinopathy: A Case Report. ( 26902864 )
2016
10
Reply to the Letter to the Editor: Is the flexion strength really increased after tenodesis for tendinopathy of the Long Head of the Biceps? ( 27106925 )
2016
11
Photobiomodulation therapy on collagen type I and III, vascular endothelial growth factor, and metalloproteinase in experimentally induced tendinopathy in aged rats. ( 27624782 )
2016
12
Extracorporeal shock wave therapy, ultrasound-guided percutaneous lavage, corticosteroid injection and combined treatment for the treatment of rotator cuff calcific tendinopathy: a network meta-analysis of RCTs. ( 27554465 )
2016
13
Forefoot and rearfoot contributions to the lunge position in individuals with and without insertional Achilles tendinopathy. ( 27209257 )
2016
14
Towards an Understanding of the Genetics of Tendinopathy. ( 27535252 )
2016
15
Reduction of the subacromial space in athletes with and without rotator cuff tendinopathy and its association with the strength of scapular muscles. ( 27102401 )
2016
16
Bridge Tenodesis: A Secure Fixation Technique for Biceps Long Head Tendinopathy During Arthroscopic Rotator Cuff Repair Using a Suture-Bridge Technique. ( 27909678 )
2016
17
Utility of clinical tests to diagnose MRI-confirmed gluteal tendinopathy in patients presenting with lateral hip pain. ( 27633027 )
2016
18
Proximal Hamstring Tendinopathy: Clinical Aspects of Assessment and Management. ( 27084841 )
2016
19
Dose-Related and Time-Dependent Development of Collagenase-Induced Tendinopathy in Rats. ( 27548063 )
2016
20
A 3-Arm Randomized Trial for Achilles Tendinopathy: Eccentric Training, Eccentric Training Plus a Dietary Supplement Containing Mucopolysaccharides, or Passive Stretching Plus a Dietary Supplement Containing Mucopolysaccharides. ( 28053674 )
2016
21
Human Genetic Variation, Sport and Exercise Medicine, and Achilles Tendinopathy: Role for Angiogenesis-Associated Genes. ( 27631191 )
2016
22
Vascular Endothelial Growth Factor Receptor-2 Polymorphisms Have Protective Effect against the Development of Tendinopathy in Volleyball Athletes. ( 27930691 )
2016
23
Degradation of elastic fiber and elavated elastase expression in long head of biceps tendinopathy. ( 27935111 )
2016
24
Role of VEGF, Nitric Oxide, and Sympathetic Neurotransmitters in the Pathogenesis of Tendinopathy: A Review of the Current Evidences. ( 27555817 )
2016
25
Effectiveness of eccentric exercise in upper limb tendinopathy? ( 27177871 )
2016
26
Adding a Transverse Scan in the Ultrasound Diagnosis of Extensor Tendinopathy. ( 27631387 )
2016
27
PRP Treatment Efficacy for Tendinopathy: A Review of Basic Science Studies. ( 27610386 )
2016
28
Increase in passive muscle tension of the quadriceps muscle heads in jumping athletes with patellar tendinopathy. ( 27539811 )
2016
29
Outcome of Extracorporeal Shock Wave Therapy for Insertional Achilles Tendinopathy with and without Haglund's Deformity. ( 28042570 )
2016
30
Polydeoxyribonucleotide injection in the treatment of chronic supraspinatus tendinopathy: a case-controlled, retrospective, comparative study of 6-month follow-up. ( 27914921 )
2016
31
Autologous Blood and Platelet Rich Plasma Injections in the Treatment of Achilles Tendinopathy: A Critically Appraised Topic. ( 27632817 )
2016
32
Comparison of three types of exercise in the treatment of rotator cuff tendinopathy/shoulder impingement syndrome: A randomized controlled trial. ( 27884499 )
2016
33
Low-Level Laser Therapy and Cryotherapy as Mono- and Adjunctive Therapies for Achilles Tendinopathy in Rats. ( 27627685 )
2016
34
Arthroscopic excision of giant cell tumor of the tendon sheath in the knee mimicking patellar tendinopathy: A case report. ( 27123148 )
2016
35
Surgical treatment of insertional Achilles tendinopathy: a systematic review. ( 28002910 )
2016
36
Fluoroquinolone-Associated Tendinopathy: Does Levofloxacin Pose the Greatest Risk? ( 27138564 )
2016
37
Cross-cultural adaptation of VISA-P score for patellar tendinopathy in Turkish population. ( 27652029 )
2016
38
Arthroscopic Treatment of Patellar Tendinopathy: Use of 70A^ Arthroscope and Superolateral Portal. ( 27909679 )
2016
39
Adipose-Derived Stem Cells Improve Collagenase-Induced Tendinopathy in a Rat Model. ( 27159294 )
2016
40
Increased Upper Trapezius Muscle Stiffness in Overhead Athletes with Rotator Cuff Tendinopathy. ( 27159276 )
2016
41
Treatment of proximal hamstring tendinopathy-related sciatic nerve entrapment: presentation of an ultrasound-guided "Intratissue Percutaneous Electrolysis" application. ( 27900300 )
2016
42
Intramuscular migration of calcific tendinopathy in the rotator cuff: ultrasound appearance and a review of the literature. ( 27635162 )
2016
43
CURRENT CONCEPTS IN THE TREATMENT OF PATELLAR TENDINOPATHY. ( 27904789 )
2016
44
Pain, not structural impairments may explain activity limitations in people with gluteal tendinopathy or hip osteoarthritis: A cross sectional study. ( 27951482 )
2016
45
Lateral elbow tendinopathy: Evidence of physiotherapy management. ( 27622145 )
2016
46
Association Between Cardiovascular Disease Risk Factors and Rotator Cuff Tendinopathy: Cross-Sectional Study. ( 28002354 )
2016
47
Clinical and Functional Outcomes of Gastrocnemius Recession for Chronic Achilles Tendinopathy. ( 27621265 )
2016
48
Comparison of peritendinous hyaluronan injections versus extracorporeal shock wave therapy in the treatment of painful Achilles tendinopathy: A randomized clinical efficacy and safety study. ( 27639439 )
2016
49
Fat pads adjacent to tendinopathy: more than a coincidence? ( 27553835 )
2016
50
Is the flexion strength really increased after tenodesis for tendinopathy of the long head of the biceps? ( 27216849 )
2016

Variations for Tendinopathy

Expression for Tendinopathy

Search GEO for disease gene expression data for Tendinopathy.

Pathways for Tendinopathy

GO Terms for Tendinopathy

Cellular components related to Tendinopathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.65 COL5A1 DCN ENPP1 MMP8 VCAN
2 extracellular region GO:0005576 9.63 COL5A1 DCN ENPP1 MMP1 MMP8 VCAN
3 Golgi lumen GO:0005796 9.37 DCN VCAN
4 proteinaceous extracellular matrix GO:0005578 9.35 COL5A1 DCN MMP1 MMP8 VCAN
5 lysosomal lumen GO:0043202 9.32 DCN VCAN
6 extracellular matrix GO:0031012 9.02 COL5A1 DCN MMP1 MMP8 VCAN

Biological processes related to Tendinopathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.5 COL5A1 DCN VCAN
2 glycosaminoglycan metabolic process GO:0030203 9.4 DCN VCAN
3 chondroitin sulfate biosynthetic process GO:0030206 9.37 DCN VCAN
4 chondroitin sulfate catabolic process GO:0030207 9.26 DCN VCAN
5 dermatan sulfate biosynthetic process GO:0030208 9.16 DCN VCAN
6 extracellular matrix disassembly GO:0022617 9.13 DCN MMP1 MMP8
7 collagen catabolic process GO:0030574 8.8 COL5A1 MMP1 MMP8

Molecular functions related to Tendinopathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.26 ENPP1 MMP1 MMP8 VCAN
2 extracellular matrix structural constituent GO:0005201 9.16 COL5A1 VCAN
3 glycosaminoglycan binding GO:0005539 8.62 DCN VCAN

Sources for Tendinopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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