Aliases & Classifications for Tendinosis

MalaCards integrated aliases for Tendinosis:

Name: Tendinosis 38 37 69

External Ids:

UMLS 69 C1568363

Summaries for Tendinosis

MalaCards based summary : Tendinosis is related to tendinopathy and tendinitis. An important gene associated with Tendinosis is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways are PAK Pathway and MAPK signaling pathway. The drugs Menthol and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, whole blood and bone, and related phenotypes are homeostasis/metabolism and behavior/neurological

Wikipedia : 72 Tendinosis, means or sometimes called chronic tendinitis, chronic tendinopathy, or chronic tendon... more...

Related Diseases for Tendinosis

Diseases related to Tendinosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 tendinopathy 30.3 DCN MMP1
2 tendinitis 11.3
3 presynaptic congenital myasthenic syndromes 10.5 CHAT SLC18A3
4 superior limbic keratoconjunctivitis 10.4 MMP1 MMP3
5 supranuclear palsy, progressive, 1 10.4 ACHE CHAT TH
6 hypoganglionosis 10.3 ACHE TH
7 spastic entropion 10.3 MMP1 MMP3
8 episodic pain syndrome, familial, 1 10.2
9 squamous cell carcinoma of the hypopharynx 10.2 MMP1 MMP3 TIMP1
10 conjunctivochalasis 10.2 MMP1 MMP3 TIMP1
11 aortic aneurysm, familial thoracic 1 10.2 MMP1 TGFB2 TGFBR2
12 varicose veins 10.2 MMP1 MMP3 TIMP1
13 bone inflammation disease 10.2 MMP1 MMP3 TIMP1
14 gingival fibromatosis 10.2 MMP1 MMP3 TIMP1
15 aortic aneurysm 10.1 TGFB2 TGFBR2 TIMP1
16 periodontitis 10.1 MMP1 MMP3 TIMP1
17 neonatal hypoxic and ischemic brain injury 10.1 BDNF TH
18 sydenham chorea 10.1 BDNF CXCL10
19 toxic encephalopathy 10.1 ACHE BDNF TH
20 periodontal disease 10.0 MMP1 MMP3 TIMP1
21 neuronitis 10.0
22 keratoconus 10.0 MMP1 MMP3 TGFB2 TIMP1
23 adult astrocytic tumour 10.0 BDNF MMP1 MMP3
24 nervous system disease 9.9 ACHE BDNF CHAT TH
25 paine syndrome 9.9
26 bursitis 9.9
27 chronic pain 9.9
28 eating disorder 9.9 BDNF CNR1 NPY
29 gingival overgrowth 9.8 DCN MMP1 MMP3 TIMP1
30 aortic aneurysm, familial abdominal, 1 9.8 DCN MMP1 MMP3 TIMP1
31 amnestic disorder 9.8 ACHE BDNF CHAT CNR1
32 cannabis abuse 9.8 BDNF CNR1
33 body mass index quantitative trait locus 11 9.8
34 body mass index quantitative trait locus 9 9.8
35 body mass index quantitative trait locus 8 9.8
36 body mass index quantitative trait locus 4 9.8
37 body mass index quantitative trait locus 10 9.8
38 body mass index quantitative trait locus 7 9.8
39 body mass index quantitative trait locus 12 9.8
40 body mass index quantitative trait locus 14 9.8
41 body mass index quantitative trait locus 18 9.8
42 epicondylitis 9.8
43 periarthritis 9.8
44 astrocytoma 9.8
45 mood disorder 9.8 BDNF NPY TH
46 drug dependence 9.7 BDNF CHRM2 CNR1
47 ewing sarcoma 9.7 MMP1 MMP3 NPY PDGFRB TGFBR2
48 central nervous system disease 9.7 ACHE BDNF CHAT CNR1 TH
49 parkinson disease, late-onset 9.6 ACHE BDNF CHAT CNR1 TH
50 amyotrophic lateral sclerosis 1 9.6 BDNF CHAT CNR1 SLC18A3 TH

Graphical network of the top 20 diseases related to Tendinosis:



Diseases related to Tendinosis

Symptoms & Phenotypes for Tendinosis

MGI Mouse Phenotypes related to Tendinosis:

43 (show all 19)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.46 ACHE BDNF CHAT CHRM2 CNR1 CXCL10
2 behavior/neurological MP:0005386 10.39 BDNF CHAT CHRM2 CNR1 DCN NPY
3 growth/size/body region MP:0005378 10.37 TIMP1 TNFRSF1A TGFBR2 TH ACHE BDNF
4 mortality/aging MP:0010768 10.32 ACHE BDNF CHAT CNR1 CXCL10 DCN
5 nervous system MP:0003631 10.28 PDGFRB SLC17A6 SLC18A3 TGFB2 TGFBR2 TH
6 cardiovascular system MP:0005385 10.22 CHAT CHRM2 CXCL10 PDGFRB TGFB2 TGFBR2
7 digestive/alimentary MP:0005381 10.2 BDNF CHAT CNR1 DCN NPY PDGFRB
8 endocrine/exocrine gland MP:0005379 10.14 TGFB2 TGFBR2 TH TIMP1 TNFRSF1A BDNF
9 adipose tissue MP:0005375 10.13 ACHE CNR1 NPY PDGFRB SLC17A6 TGFBR2
10 muscle MP:0005369 10.11 ACHE CHAT CHRM2 DCN PDGFRB SLC18A3
11 craniofacial MP:0005382 10.1 ACHE BDNF DCN PDGFRB TGFB2 TGFBR2
12 integument MP:0010771 10.1 SLC17A6 TH TNFRSF1A BDNF CHRM2 CNR1
13 normal MP:0002873 9.97 CHAT CNR1 DCN NPY PDGFRB SLC17A6
14 neoplasm MP:0002006 9.91 DCN MMP1 TGFBR2 TH TIMP1 TNFRSF1A
15 no phenotypic analysis MP:0003012 9.91 ACHE BDNF CNR1 SLC17A6 SLC18A3 TH
16 reproductive system MP:0005389 9.91 ACHE BDNF CHAT CNR1 DCN PDGFRB
17 respiratory system MP:0005388 9.9 ACHE BDNF CHAT CHRM2 DCN SLC17A6
18 skeleton MP:0005390 9.7 CHAT CNR1 DCN MMP3 NPY PDGFRB
19 vision/eye MP:0005391 9.32 PDGFRB TGFB2 TGFBR2 TH TNFRSF1A ACHE

Drugs & Therapeutics for Tendinosis

Drugs for Tendinosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Menthol Approved Phase 4 2216-51-5 16666
2
Lidocaine Approved, Vet_approved Phase 4,Phase 1,Phase 2 137-58-6 3676
3 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3
4 Anesthetics Phase 4,Phase 1,Phase 2
5 Anesthetics, Local Phase 4,Phase 1,Phase 2
6
Bupivacaine Approved, Investigational Phase 2, Phase 3 38396-39-3, 2180-92-9 2474
7
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3 83-43-2 6741
8
Prednisolone Approved, Vet_approved Phase 2, Phase 3 50-24-8 5755
9
Thrombin Approved, Investigational Phase 2, Phase 3
10 Antiemetics Phase 2, Phase 3
11 Anti-Inflammatory Agents Phase 2, Phase 3
12 Antineoplastic Agents, Hormonal Phase 2, Phase 3
13 Autonomic Agents Phase 2, Phase 3
14 Gastrointestinal Agents Phase 2, Phase 3
15 glucocorticoids Phase 2, Phase 3
16 Hormone Antagonists Phase 2, Phase 3
17 Hormones Phase 2, Phase 3
18 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3
19 Methylprednisolone acetate Phase 2, Phase 3
20 Methylprednisolone Hemisuccinate Phase 2, Phase 3
21 Neuroprotective Agents Phase 2, Phase 3
22 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 1
23 Prednisolone acetate Phase 2, Phase 3
24 Prednisolone hemisuccinate Phase 2, Phase 3
25 Prednisolone phosphate Phase 2, Phase 3
26 Protective Agents Phase 2, Phase 3
27 Calamus Nutraceutical Phase 2, Phase 3
28
Triamcinolone Approved, Vet_approved Phase 2 124-94-7 31307
29
Benzocaine Approved, Investigational Phase 2 1994-09-7, 94-09-7 2337
30 tannic acid Approved, Nutraceutical Phase 2
31 Anti-Arrhythmia Agents Phase 1, Phase 2
32 Central Nervous System Depressants Phase 1, Phase 2
33 Diuretics, Potassium Sparing Phase 1, Phase 2
34 Sodium Channel Blockers Phase 1, Phase 2
35 Immunosuppressive Agents Phase 2
36 triamcinolone acetonide Phase 2
37 Triamcinolone diacetate Phase 2
38 Triamcinolone hexacetonide Phase 2
39 Calcium, Dietary
40 Mitogens
41 Performance-Enhancing Substances

Interventional clinical trials:

(show all 31)

# Name Status NCT ID Phase Drugs
1 Achilles Tendinosis Study; Comparison of Radiofrequency to Surgical MicroDebridement Completed NCT00534781 Phase 4
2 Radio-frequency (RF)-Based Plasma Micro-tenotomy for the Treatment of Shoulder Impingement Syndrome Completed NCT01554670 Phase 4
3 Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer Completed NCT00950053 Phase 4
4 Bundang Rehabilitative Impact Study of the Elbow Epicondylitis Completed NCT02492945 Phase 4 3ml-Rejuvinex;3ml-15%-dextrose solution
5 The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis Not yet recruiting NCT03363789 Phase 4
6 Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy Terminated NCT02978833 Phase 4
7 Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis Withdrawn NCT00420875 Phase 4
8 Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff Tendinosis Unknown status NCT00196573 Phase 3
9 A Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral Epicondylitis Completed NCT00947765 Phase 2, Phase 3 Local corticosteroid injection
10 Impact of Autologous Platelet Rich Plasma on Healing of Rotator Cuff Repairs Completed NCT01000935 Phase 2, Phase 3
11 A Dynamic Elastic Garment (DEG) in Patients With Rotator Cuff Tendinopathy Recruiting NCT03032432 Phase 3 Corticosteroid injection
12 Hyaluronate Injection for Lateral Epicondylitis Recruiting NCT02258295 Phase 3 Intragel;Saline
13 A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection Completed NCT01600326 Phase 2 Ultrasound guided platelet rich plasma injection
14 Effectiveness of Dextrose Injection for Osgood-Schlatter Disease Completed NCT01300754 Phase 1, Phase 2
15 Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC) Recruiting NCT03449082 Phase 2 Fibrin glue;Normal saline
16 PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis Recruiting NCT03072381 Phase 2 Corticosteroid Control - Group 2
17 Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy Enrolling by invitation NCT01843504 Phase 2
18 Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis Terminated NCT02330146 Phase 1, Phase 2 RCT-01;Placebo
19 Exercise and Shoe Orthoses in Treatment of Posterior Tibial Tendon Dysfunction Completed NCT00279630 Phase 1
20 Radiofrequency Microtenotomy for Treatment of Rotator Cuff Tendinopathy Completed NCT02275689
21 Long Duration Therapeutic Ultrasound for Tendon Healing Completed NCT02466308
22 Steroid Versus Platelet Rich Plasma Injection for Chronic Low Back Pain Completed NCT02334475
23 Physiotherapy or Acupuncture for Lateral Epicondylitis Completed NCT02321696
24 Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) Injections Completed NCT01200875
25 Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients Recruiting NCT03000205
26 Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma Recruiting NCT01406821
27 Cellular & Biocellular Regenerative Therapy in Musculoskeletal Pain, Dysfunction,Degenerative or Inflammatory Disease Recruiting NCT03090672 Normal Saline
28 Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles Tendinopathy Recruiting NCT02732782
29 Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic Tendinosis Active, not recruiting NCT01833598
30 Effects of Isoinertial Training on Rotator Cuff Tendinopathy Not yet recruiting NCT02982460
31 Long-Term Follow-up of the Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis Withdrawn NCT02655042

Search NIH Clinical Center for Tendinosis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tendinosis cell therapies at LifeMap Discovery.

Genetic Tests for Tendinosis

Anatomical Context for Tendinosis

MalaCards organs/tissues related to Tendinosis:

38
Skin, Whole Blood, Bone, Bone Marrow

Publications for Tendinosis

Articles related to Tendinosis:

(show top 50) (show all 71)
# Title Authors Year
1
Greater trochanteric pain syndrome and gluteus medius and minimus tendinosis: nonsurgical treatment. ( 29182042 )
2018
2
Predicting Failure of Nonoperative Treatment for Insertional Achilles Tendinosis. ( 28884594 )
2017
3
Ultrasonic Percutaneous Tenotomy for Recalcitrant Calcific Triceps Tendinosis in a Competitive Strongman: A Case Report. ( 28498222 )
2017
4
Tendinosis (Tendinitis) ( 28846334 )
2017
5
Proximal Hamstring Tendinosis and Partial Ruptures. ( 28195608 )
2017
6
Platelet-Rich Plasma Injections as a Treatment for Refractory Patellar Tendinosis: A Meta-Analysis of Randomised Trials. ( 28854761 )
2017
7
Radiofrequency Microdebridement Versus Surgical Decompression for Achilles Tendinosis: A Randomized Controlled Trial. ( 28495412 )
2017
8
Greater Trochanteric Pain Syndrome: Percutaneous Tendon Fenestration Versus Platelet-Rich Plasma Injection for Treatment of Gluteal Tendinosis. ( 27663654 )
2016
9
Return to Sport and Physical Activity After Calcaneoplasty for Insertional Achilles Tendinosis. ( 27600485 )
2016
10
Comparison of Clinical Efficacy Among Endoscopy-Assisted Radio-Frequency Ablation, Extracorporeal Shockwaves, and Eccentric Exercises in Treatment of Insertional Achilles Tendinosis. ( 27723374 )
2016
11
Efficacy of Achilles Suture Bridge Technique for Insertional Achilles Tendinosis in an Obese and Athletic Patient. ( 27644578 )
2016
12
High Power Laser for Treatment of Achilles Tendinosis - a Single Blind Randomized Placebo Controlled Clinical Study. ( 27330704 )
2016
13
Technical Innovation Case Report: Ultrasound-Guided Prolotherapy Injection for Insertional Achilles Calcific Tendinosis. ( 27974984 )
2016
14
Surgical Technique: Jumper's Knee-Arthroscopic Treatment of Chronic Tendinosis of the Patellar Tendon. ( 28149740 )
2016
15
T2 * relaxation time in Achilles tendinosis and controls and its correlation with clinical score. ( 26605756 )
2016
16
Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. ( 27469590 )
2016
17
Plantaris Excision Reduces Pain in Midportion Achilles Tendinopathy Even in the Absence of Plantaris Tendinosis. ( 28203584 )
2016
18
CORR Insights(Ar): Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. ( 27572298 )
2016
19
Management of rotator cuff calcific tendinosis guided by ultrasound elastography. ( 26143386 )
2015
20
Quantitative MRI characterization of arthroscopically verified supraspinatus pathology: comparison of tendon tears, tendinosis and asymptomatic supraspinatus tendons with T2 mapping. ( 25739912 )
2015
21
Achilles tendinosis: treatment options. ( 25729512 )
2015
22
The molecular systemic and local effects of intra-tendinous injection of Platelet Rich Plasma in tendinosis: preliminary results on a rat model with ELISA method. ( 26261788 )
2015
23
Gastrocnemius tendinosis-A frequent finding on MRI knee examination. ( 26456309 )
2015
24
Amniotic Tissues for the Treatment of Chronic Plantar Fasciosis and Achilles Tendinosis. ( 26491722 )
2015
25
A retrospective comparison of the management of recalcitrant lateral elbow tendinosis: platelet-rich plasma injections versus surgery. ( 26034445 )
2015
26
Peroneal tendinosis as a predisposing factor for the acute lateral ankle sprain in runners. ( 25786820 )
2015
27
Retraction. Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. ( 25878311 )
2015
28
Update to the retraction of "Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results" by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. ( 26085535 )
2015
29
Asymptomatic Elite Adolescent Tennis Players' Signs of Tendinosis in Their Dominant Shoulder Compared With Their Nondominant Shoulder. ( 26651279 )
2015
30
The neuromechanical adaptations to Achilles tendinosis. ( 26046962 )
2015
31
Results of Surgical Treatment of Chronic Patellar Tendinosis (Jumper's Knee): A Systematic Review of the Literature. ( 26248496 )
2015
32
An Achilles tendinosis masking an intramedullary astrocytoma. ( 25322734 )
2014
33
Combined intra-tendinous injection of Platelet Rich Plasma and bevacizumab accelerates and improves healing compared to Platelet Rich Plasma in tendinosis: comprehensive assessment on a rat model. ( 25489554 )
2014
34
The impact of posture on wrist tendinosis among blue-collar workers: the San Francisco study. ( 24669549 )
2014
35
Sonoelastography findings of biceps tendinitis and tendinosis. ( 25368684 )
2014
36
Percutaneous ultrasonic tenotomy for chronic elbow tendinosis: a prospective study. ( 25306494 )
2014
37
Plantar Flexor Muscle Architecture Changes as a Result of Eccentric Exercise in Patients With Achilles Tendinosis. ( 25037955 )
2014
38
Trigger finger, tendinosis, and intratendinous gene expression. ( 22882155 )
2014
39
The plantaris tendon in association with mid-portion Achilles tendinosis: tendinosis-like morphological features and presence of a non-neuronal cholinergic system. ( 23378267 )
2013
40
Injectable treatments for noninsertional achilles tendinosis: a systematic review. ( 23637232 )
2013
41
Flexor hallucis longus tendon transfer in treatment of Achilles tendinosis. ( 23283373 )
2013
42
Acute calcific tendinosis of the flexor hallucis brevis: case report. ( 23729205 )
2013
43
Dynamic contrast enhanced magnetic resonance imaging in chronic Achilles tendinosis. ( 24261480 )
2013
44
Early weightbearing using Achilles suture bridge technique for insertional Achilles tendinosis: a review of 43 patients. ( 23669005 )
2013
45
Efficacy of intra-tendinous injection of platelet-rich plasma in treating tendinosis: comprehensive assessment of a rat model. ( 23801419 )
2013
46
Achilles tendon reattachment after surgical treatment of insertional tendinosis using the suture bridge technique: a case series. ( 22579354 )
2012
47
Is calcaneal inclination higher in patients with insertional Achilles tendinosis? A case-controlled, cross-sectional study. ( 22819613 )
2012
48
Is percutaneous radiofrequency coblation for treatment of Achilles tendinosis safe and effective? ( 22974813 )
2012
49
Tendinopathy: why the difference between tendinitis and tendinosis matters. ( 22553479 )
2012
50
Effects of tendon viscoelasticity in Achilles tendinosis on explosive performance and clinical severity in athletes. ( 22830527 )
2012

Variations for Tendinosis

Expression for Tendinosis

Search GEO for disease gene expression data for Tendinosis.

Pathways for Tendinosis

Pathways related to Tendinosis according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.07 BDNF CXCL10 PDGFRB TGFB2 TGFBR2 TIMP1
2 12.6 BDNF PDGFRB TGFB2 TGFBR2 TNFRSF1A
3
Show member pathways
12.58 DCN MMP1 MMP3 TGFB2 TIMP1
4
Show member pathways
12.4 CXCL10 TGFB2 TGFBR2 TNFRSF1A
5
Show member pathways
12.4 ACHE CHAT CHRM2 SLC17A6 SLC18A3 TH
6 12.27 PDGFRB TGFB2 TGFBR2 TNFRSF1A
7 11.89 MMP1 TGFB2 TGFBR2 TNFRSF1A
8 11.85 MMP1 MMP3 TIMP1
9 11.83 BDNF CHAT CHRM2 TH
10 11.81 CXCL10 MMP3 TNFRSF1A
11
Show member pathways
11.76 MMP1 MMP3 TIMP1
12 11.71 MMP1 MMP3 TGFB2
13 11.66 DCN TGFB2 TGFBR2
14 11.62 BDNF CHAT TH
15
Show member pathways
11.49 MMP1 MMP3 TNFRSF1A
16 11.46 MMP1 MMP3 TIMP1
17 11.35 ACHE TGFB2 TH
18 11.27 CXCL10 TIMP1 TNFRSF1A
19 11.2 MMP3 PDGFRB TGFB2 TIMP1
20 10.9 MMP1 TIMP1
21 10.88 BDNF CXCL10 PDGFRB TGFB2 TIMP1
22 10.84 TGFB2 TGFBR2
23
Show member pathways
10.67 ACHE CHAT TH
24 10.32 ACHE CHAT
25 10 ACHE CHAT SLC18A3 TH

GO Terms for Tendinosis

Cellular components related to Tendinosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 ACHE CXCL10 DCN MMP3 NPY TGFB2
2 synapse GO:0045202 9.65 ACHE CHAT CHRM2 SLC17A6 SLC18A3
3 extracellular matrix GO:0031012 9.35 DCN MMP1 MMP3 TGFB2 TIMP1
4 extracellular region GO:0005576 9.32 ACHE BDNF CXCL10 DCN MMP1 MMP3

Biological processes related to Tendinosis according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.93 CXCL10 PDGFRB TGFB2 TGFBR2 TIMP1
2 regulation of receptor activity GO:0010469 9.85 BDNF CXCL10 NPY TGFB2 TIMP1
3 animal organ morphogenesis GO:0009887 9.75 DCN TGFBR2 TH
4 negative regulation of angiogenesis GO:0016525 9.73 CXCL10 DCN TGFB2
5 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.65 DCN PDGFRB TGFB2
6 response to lipopolysaccharide GO:0032496 9.65 CNR1 CXCL10 DCN TH TNFRSF1A
7 extracellular matrix disassembly GO:0022617 9.62 DCN MMP1 MMP3 TIMP1
8 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.58 CHRM2 CNR1 NPY
9 positive regulation of protein oligomerization GO:0032461 9.57 MMP1 MMP3
10 pathway-restricted SMAD protein phosphorylation GO:0060389 9.55 TGFB2 TGFBR2
11 atrioventricular valve morphogenesis GO:0003181 9.52 TGFB2 TGFBR2
12 dopamine biosynthetic process GO:0042416 9.51 TGFB2 TH
13 membranous septum morphogenesis GO:0003149 9.49 TGFB2 TGFBR2
14 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007 9.43 TGFB2 TGFBR2
15 endocardial cushion fusion GO:0003274 9.37 TGFB2 TGFBR2
16 aging GO:0007568 9.35 CNR1 DCN PDGFRB TGFBR2 TIMP1
17 neurotransmitter biosynthetic process GO:0042136 9.33 ACHE CHAT TH
18 wound healing GO:0042060 9.02 DCN PDGFRB TGFB2 TGFBR2 TIMP1

Molecular functions related to Tendinosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acetylcholine binding GO:0042166 8.62 ACHE SLC18A3

Sources for Tendinosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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