Aliases & Classifications for Tendinosis

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Aliases & Descriptions for Tendinosis:

Name: Tendinosis 34 33 66

Summaries for Tendinosis

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Wikipedia:69 Tendinosis, sometimes called chronic tendinitis, chronic tendinopathy, or chronic tendon injury, is... more...

MalaCards based summary: Tendinosis is related to tendinitis and small intestine cancer, childhood. An important gene associated with Tendinosis is CHAT (Choline O-Acetyltransferase), and among its related pathways are Acetylcholine Synthesis and Immune response_Oncostatin M signaling via JAK-Stat in human cells. Affiliated tissues include skin, bone and bone marrow, and related mouse phenotypes are neoplasm and craniofacial.

Related Diseases for Tendinosis

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Diseases related to Tendinosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
idRelated DiseaseScoreTop Affiliating Genes
1tendinitis10.7
2small intestine cancer, childhood10.6MMP1, MMP3
3pathological gambling10.6MMP1, MMP3
4hypogonadism cardiomyopathy10.5ACHE, TH
5congenital chloride diarrhea10.5MMP1, MMP3
6melorheostosis10.4MMP1, MMP3, TIMP1
7salt and pepper syndrome10.4MMP1, MMP3, TIMP1
8granulomatous orchitis10.4MMP1, MMP3, TIMP1
9siberian tick typhus10.4ACHE, CHAT
10stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features10.4BDNF, CXCL10
11lung hilum cancer10.4MMP1, MMP3, TIMP1
12xanthomatosis10.4MMP1, MMP3, TIMP1
13chronic rhinitis10.3MMP1, MMP3, TIMP1
14immunodeficiency 27b, mycobacteriosis, ad10.3MMP3, TIMP1
15angiomyolipoma10.2BDNF, CHAT, TH
16transsexualism10.2BDNF, CHAT, CNR1
17juvenile astrocytoma10.2MMP1, MMP3
18tendinopathy10.1
19chronic intestinal vascular insufficiency10.1BDNF, CHAT, TH
20lymphosarcoma10.1BDNF, CNR1, NPY
21neuronitis10.1
22bursitis10.0
23chronic pain10.0
24purpura10.0BDNF, CNR1, NPY, TH
25parkinson disease, late-onset9.9BDNF, CHAT, CNR1, TH
26obesity9.8
27epicondylitis9.8
28periarthritis9.8
29astrocytoma9.8
30long qt syndrome 59.8BDNF, CHAT, CNR1, SLC18A3, TH
31narcolepsy 29.8BDNF, CHRM2, CNR1, NPY
32encephalopathy, neonatal severe9.7BDNF, CHAT, TH
3346 xy gonadal dysgenesis9.6TGFB2, TIMP1, TNFRSF1A
34malignant struma ovarii9.6TGFB2, TGFBR2, TIMP1
35adenosine monophosphate deaminase deficiency erythrocyte type9.6TGFB2, TGFBR2
36multiple sclerosis, disease progression, modifier of9.6BDNF, CNR1, CXCL10, TNFRSF1A
37childhood spinal cord tumor9.5TGFB2, TGFBR2, TIMP1
38west syndrome4.8ACHE, BDNF, CHAT, CHRM2, CNR1, CXCL10

Graphical network of the top 20 diseases related to Tendinosis:



Diseases related to tendinosis

Symptoms for Tendinosis

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Drugs & Therapeutics for Tendinosis

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Drugs for Tendinosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MentholPhase 421842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
2
LidocainePhase 4, Phase 1, Phase 21168137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
3PREDNISOLONE ACETATEPhase 2, Phase 31118
4THROMBINPhase 2, Phase 3284
5
PrednisolonePhase 2, Phase 3111850-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
6
MethylprednisolonePhase 2, Phase 3111883-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
7
BupivacainePhase 2, Phase 310562180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
8glucocorticoidsPhase 2, Phase 34756
9
Hyaluronic acidPhase 34199004-61-953477741, 24759
Synonyms:
Hyaluronan
Hyaluronate
Hyaluronic acid
Hylartil
Hyruan Plus
Luronit
 
Macronan
Mucoitin
Nutra-HAF
Q 5AQ
Sepracoat
Sepragel Sinus
Sofast
Synvisc
10
BenzocainePhase 217941994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
11tannic acidNutraceuticalPhase 21794

Interventional clinical trials:

(show all 23)
idNameStatusNCT IDPhase
1Achilles Tendinosis Study; Comparison of Radiofrequency to Surgical MicroDebridementCompletedNCT00534781Phase 4
2Radio-frequency (RF)-Based Plasma Micro-tenotomy for the Treatment of Shoulder Impingement SyndromeCompletedNCT01554670Phase 4
3Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon TransferCompletedNCT00950053Phase 4
4Bundang Rehabilitative Impact Study of the Elbow EpicondylitisEnrolling by invitationNCT02492945Phase 4
5Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar FasciosisWithdrawnNCT00420875Phase 4
6A Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral EpicondylitisCompletedNCT00947765Phase 2, Phase 3
7Impact of Autologous Platelet Rich Plasma on Healing of Rotator Cuff RepairsCompletedNCT01000935Phase 2, Phase 3
8Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff TendinosisActive, not recruitingNCT00196573Phase 3
9Hyaluronate Injection for Lateral EpicondylitisNot yet recruitingNCT02258295Phase 3
10Effectiveness of Dextrose Injection for Osgood-Schlatter DiseaseCompletedNCT01300754Phase 1, Phase 2
11Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles TendinosisActive, not recruitingNCT02330146Phase 1, Phase 2
12Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar TendinopathyEnrolling by invitationNCT01843504Phase 2
13Exercise and Shoe Orthoses in Treatment of Posterior Tibial Tendon DysfunctionCompletedNCT00279630Phase 1
14Radiofrequency Microtenotomy for Treatment of Rotator Cuff TendinopathyRecruitingNCT02275689Phase 1
15Long Duration Therapeutic Ultrasound for Tendon HealingCompletedNCT02466308
16Steroid Versus Platelet Rich Plasma Injection for Chronic Low Back PainCompletedNCT02334475
17Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich PlasmaRecruitingNCT01406821
18Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic TendinosisRecruitingNCT01833598
19Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles TendinopathyRecruitingNCT02732782
20Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) InjectionsRecruitingNCT01200875
21Physiotherapy or Acupuncture for Lateral EpicondylitisRecruitingNCT02321696
22A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma InjectionActive, not recruitingNCT01600326
23Long-Term Follow-up of the Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles TendinosisWithdrawnNCT02655042

Search NIH Clinical Center for Tendinosis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tendinosis cell therapies at LifeMap Discovery.

Genetic Tests for Tendinosis

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Anatomical Context for Tendinosis

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MalaCards organs/tissues related to Tendinosis:

34
Skin, Bone, Bone marrow

Animal Models for Tendinosis or affiliated genes

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MGI Mouse Phenotypes related to Tendinosis:

39 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7DCN, MMP1, TGFBR2, TH, TIMP1, TNFRSF1A
2MP:00053828.1ACHE, BDNF, DCN, PDGFRB, TGFB2, TGFBR2
3MP:00107718.1BDNF, CHRM2, CNR1, DCN, PDGFRB, SLC17A6
4MP:00053758.1ACHE, CNR1, NPY, PDGFRB, SLC17A6, TGFBR2
5MP:00030127.9ACHE, BDNF, CNR1, SLC17A6, SLC18A3, TH
6MP:00053897.9ACHE, BDNF, CHAT, CNR1, DCN, PDGFRB
7MP:00053797.5BDNF, DCN, PDGFRB, TGFB2, TGFBR2, TH
8MP:00053857.5CHAT, CHRM2, CXCL10, PDGFRB, TGFB2, TGFBR2
9MP:00028737.4BDNF, CHAT, CNR1, DCN, NPY, PDGFRB
10MP:00053817.3BDNF, CHAT, CNR1, DCN, NPY, PDGFRB
11MP:00053697.0ACHE, CHAT, CHRM2, DCN, PDGFRB, SLC18A3
12MP:00053887.0ACHE, BDNF, CHRM2, DCN, SLC17A6, TGFB2
13MP:00053916.9ACHE, BDNF, CHAT, CHRM2, DCN, PDGFRB
14MP:00053906.1CHAT, CNR1, DCN, MMP3, NPY, PDGFRB
15MP:00053865.6ACHE, BDNF, CHAT, CHRM2, CNR1, DCN
16MP:00053785.5ACHE, BDNF, CHAT, CHRM2, CNR1, DCN
17MP:00107685.2ACHE, BDNF, CHAT, CNR1, CXCL10, DCN
18MP:00036315.0ACHE, BDNF, CHAT, CHRM2, CNR1, CXCL10
19MP:00053763.6ACHE, BDNF, CHAT, CHRM2, CNR1, CXCL10

Publications for Tendinosis

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Articles related to Tendinosis:

(show top 50)    (show all 60)
idTitleAuthorsYear
1
T2 * relaxation time in Achilles tendinosis and controls and its correlation with clinical score. (26605756)
2016
2
Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. (27469590)
2016
3
Return to Sport and Physical Activity After Calcaneoplasty for Insertional Achilles Tendinosis. (27600485)
2016
4
Efficacy of Achilles Suture Bridge Technique for Insertional Achilles Tendinosis in an Obese and Athletic Patient. (27644578)
2016
5
Greater Trochanteric Pain Syndrome: Percutaneous Tendon Fenestration Versus Platelet-Rich Plasma Injection for Treatment of Gluteal Tendinosis. (27663654)
2016
6
CORR Insights(Ar): Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. (27572298)
2016
7
High Power Laser for Treatment of Achilles Tendinosis - a Single Blind Randomized Placebo Controlled Clinical Study. (27330704)
2016
8
Gastrocnemius tendinosis-A frequent finding on MRI knee examination. (26456309)
2015
9
Quantitative MRI characterization of arthroscopically verified supraspinatus pathology: comparison of tendon tears, tendinosis and asymptomatic supraspinatus tendons with T2 mapping. (25739912)
2015
10
Achilles tendinosis: treatment options. (25729512)
2015
11
Retraction. Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. (25878311)
2015
12
Asymptomatic Elite Adolescent Tennis Players' Signs of Tendinosis in Their Dominant Shoulder Compared With Their Nondominant Shoulder. (26651279)
2015
13
Update to the retraction of "Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results" by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. (26085535)
2015
14
The neuromechanical adaptations to Achilles tendinosis. (26046962)
2015
15
Peroneal tendinosis as a predisposing factor for the acute lateral ankle sprain in runners. (25786820)
2015
16
A retrospective comparison of the management of recalcitrant lateral elbow tendinosis: platelet-rich plasma injections versus surgery. (26034445)
2015
17
Management of rotator cuff calcific tendinosis guided by ultrasound elastography. (26143386)
2015
18
Amniotic Tissues for the Treatment of Chronic Plantar Fasciosis and Achilles Tendinosis. (26491722)
2015
19
Sonoelastography findings of biceps tendinitis and tendinosis. (25368684)
2014
20
Plantar Flexor Muscle Architecture Changes as a Result of Eccentric Exercise in Patients With Achilles Tendinosis. (25037955)
2014
21
An Achilles tendinosis masking an intramedullary astrocytoma. (25322734)
2014
22
Percutaneous ultrasonic tenotomy for chronic elbow tendinosis: a prospective study. (25306494)
2014
23
The impact of posture on wrist tendinosis among blue-collar workers: the San Francisco study. (24669549)
2014
24
Combined intra-tendinous injection of Platelet Rich Plasma and bevacizumab accelerates and improves healing compared to Platelet Rich Plasma in tendinosis: comprehensive assessment on a rat model. (25489554)
2014
25
Early weightbearing using Achilles suture bridge technique for insertional Achilles tendinosis: a review of 43 patients. (23669005)
2013
26
Injectable treatments for noninsertional achilles tendinosis: a systematic review. (23637232)
2013
27
Acute calcific tendinosis of the flexor hallucis brevis: case report. (23729205)
2013
28
The plantaris tendon in association with mid-portion Achilles tendinosis: tendinosis-like morphological features and presence of a non-neuronal cholinergic system. (23378267)
2013
29
Flexor hallucis longus tendon transfer in treatment of Achilles tendinosis. (23283373)
2013
30
Dynamic contrast enhanced magnetic resonance imaging in chronic Achilles tendinosis. (24261480)
2013
31
Platelet rich plasma treatment for chronic Achilles tendinosis. (22735279)
2012
32
Tendinopathy: why the difference between tendinitis and tendinosis matters. (22553479)
2012
33
Eccentric training for the rehabilitation of a high level wrestler with distal biceps tendinosis: a case report. (22893861)
2012
34
Ultrasonographic evaluation of canine supraspinatus calcifying tendinosis. (23033462)
2012
35
Is calcaneal inclination higher in patients with insertional Achilles tendinosis? A case-controlled, cross-sectional study. (22819613)
2012
36
Effects of tendon viscoelasticity in Achilles tendinosis on explosive performance and clinical severity in athletes. (22830527)
2012
37
Physical activity level in Achilles tendinosis is associated with blood levels of pain-related factors: a pilot study. (21819445)
2011
38
Increased expression of cannabinoid CBa88 receptors in Achilles tendinosis. (21931835)
2011
39
VGluT2 expression in painful Achilles and patellar tendinosis: evidence of local glutamate release by tenocytes. (18050306)
2008
40
In situ hybridization studies confirming recent findings of the existence of a local nonneuronal catecholamine production in human patellar tendinosis. (17661370)
2007
41
Extensive expression of markers for acetylcholine synthesis and of M2 receptors in tenocytes in therapy-resistant chronic painful patellar tendon tendinosis - a pilot study. (17289083)
2007
42
Studies on the importance of sympathetic innervation, adrenergic receptors, and a possible local catecholamine production in the development of patellar tendinopathy (tendinosis) in man. (17206652)
2007
43
Immunohistochemical and histochemical findings favoring the occurrence of autocrine/paracrine as well as nerve-related cholinergic effects in chronic painful patellar tendon tendinosis. (16830327)
2006
44
Calcific tendinosis and periarthritis: classic magnetic resonance imaging appearance and associated findings. (15100546)
2004
45
cDNA-arrays and real-time quantitative PCR techniques in the investigation of chronic Achilles tendinosis. (14554207)
2003
46
Increased expression of matrix metalloproteinase 1 (MMP1) in 11 patients with patellar tendinosis. (12553513)
2002
47
Expression of transforming growth factor-beta isoforms and their receptors in chronic tendinosis. (11554502)
2001
48
Increased cell proliferation and associated expression of PDGFRbeta causing hypercellularity in patellar tendinosis. (11285371)
2001
49
Re: "Comparison of results of retrocalcaneal decompression for retrocalcaneal bursitis and insertional Achilles tendinosis with calcific spur" by Dr. Anthony Watson et. al. (11475463)
2001
50
Comparison of results of retrocalcaneal decompression for retrocalcaneal bursitis and insertional achilles tendinosis with calcific spur. (10966360)
2000

Variations for Tendinosis

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Expression for genes affiliated with Tendinosis

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Search GEO for disease gene expression data for Tendinosis.

Pathways for genes affiliated with Tendinosis

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Pathways related to Tendinosis according to GeneCards Suite gene sharing:

(show all 23)
idSuper pathwaysScoreTop Affiliating Genes
110.1ACHE, CHAT
210.0MMP1, TIMP1
3
Show member pathways
9.8ACHE, CHAT, TH
4
Show member pathways
9.7MMP1, MMP3, TIMP1
59.7MMP1, MMP3, TIMP1
69.7BDNF, CHAT, TH
79.5ACHE, TGFB2, TH
89.4MMP1, MMP3, TGFB2
99.4CXCL10, MMP3, TNFRSF1A
109.4BDNF, CHAT, CHRM2, TH
11
Show member pathways
9.2MMP3, PDGFRB, TGFB2, TIMP1
129.1CNR1, NPY, SLC17A6, TH
139.1BDNF, PDGFRB, TGFB2, TIMP1
149.0ACHE, CHAT, SLC18A3, TH
15
Show member pathways
8.9DCN, TGFB2, TGFBR2
16
Show member pathways
8.9DCN, TGFB2, TGFBR2
17
Show member pathways
8.8DCN, MMP1, MMP3, TGFB2, TIMP1
188.6MMP1, TGFB2, TGFBR2, TNFRSF1A
198.6PDGFRB, TGFB2, TGFBR2, TNFRSF1A
20
Show member pathways
8.3BDNF, TGFB2, TGFBR2, TIMP1, TNFRSF1A
218.2BDNF, PDGFRB, TGFB2, TGFBR2, TNFRSF1A
22
Show member pathways
7.9ACHE, CHAT, CHRM2, CNR1, SLC17A6, SLC18A3
23
Show member pathways
7.7BDNF, CXCL10, PDGFRB, TGFB2, TGFBR2, TIMP1

GO Terms for genes affiliated with Tendinosis

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Cellular components related to Tendinosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1proteinaceous extracellular matrixGO:00055789.5DCN, MMP1, MMP3, TIMP1
2extracellular spaceGO:00056157.8ACHE, CXCL10, DCN, MMP3, NPY, TGFB2
3extracellular regionGO:00055766.9ACHE, BDNF, CXCL10, DCN, MMP1, MMP3

Biological processes related to Tendinosis according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of protein oligomerizationGO:003246110.6MMP1, MMP3
2neurotransmitter biosynthetic processGO:004213610.5ACHE, TH
3dopamine biosynthetic processGO:004241610.1TGFB2, TH
4positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formationGO:190500710.0TGFB2, TGFBR2
5pathway-restricted SMAD protein phosphorylationGO:00603899.9TGFB2, TGFBR2
6memoryGO:00076139.8CHAT, CNR1, TH
7response to nutrientGO:00075849.7CHAT, CNR1, TGFBR2
8extracellular matrix disassemblyGO:00226179.7DCN, MMP1, MMP3, TIMP1
9positive regulation of phosphatidylinositol 3-kinase signalingGO:00140689.6DCN, PDGFRB, TGFB2
10animal organ morphogenesisGO:00098879.6DCN, TGFBR2, TH
11G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerGO:00071879.6CHRM2, CNR1, NPY
12agingGO:00075689.1CNR1, DCN, TGFBR2, TIMP1
13response to lipopolysaccharideGO:00324969.0CNR1, CXCL10, DCN, TH, TNFRSF1A
14response to hypoxiaGO:00016668.8CHAT, TGFB2, TGFBR2, TH
15wound healingGO:00420608.4DCN, PDGFRB, TGFB2, TGFBR2, TIMP1
16positive regulation of cell proliferationGO:00082848.2CXCL10, PDGFRB, TGFB2, TGFBR2, TIMP1

Sources for Tendinosis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet