MCID: TRT001
MIFTS: 36

Teratocarcinoma malady

Category: Cancer diseases

Aliases & Classifications for Teratocarcinoma

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Aliases & Descriptions for Teratocarcinoma:

Name: Teratocarcinoma 10 47 12 36 65
 
Mixed Embryonal Carcinoma and Teratoma 10

Classifications:



External Ids:

Disease Ontology10 DOID:3305
MeSH36 D018243
SNOMED-CT59 67830002
NCIt42 C3756
UMLS65 C0206664

Summaries for Teratocarcinoma

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Disease Ontology:10 A mixed germ cell tumor that is a mixture of teratoma with embryonal carcinoma, or with choriocarcinoma, or with both.

MalaCards based summary: Teratocarcinoma, also known as mixed embryonal carcinoma and teratoma, is related to childhood teratocarcinoma of the testis and breast cancer. An important gene associated with Teratocarcinoma is TDGF1 (Teratocarcinoma-Derived Growth Factor 1), and among its related pathways are and Glypican 1 network. Affiliated tissues include testis, ovary and testis germ, and related mouse phenotypes are hearing/vestibular/ear and embryo.

Wikipedia:68 A germ cell tumor (GCT) is a neoplasm derived from germ cells. Germ cell tumors can be cancerous or... more...

Related Diseases for Teratocarcinoma

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Graphical network of the top 20 diseases related to Teratocarcinoma:



Diseases related to teratocarcinoma

Symptoms for Teratocarcinoma

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Drugs & Therapeutics for Teratocarcinoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Teratocarcinoma


Cochrane evidence based reviews: teratocarcinoma

Genetic Tests for Teratocarcinoma

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Anatomical Context for Teratocarcinoma

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MalaCards organs/tissues related to Teratocarcinoma:

33
Testis, Ovary, Testis germ, Lung, Breast, Skin, Prostate

Animal Models for Teratocarcinoma or affiliated genes

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MGI Mouse Phenotypes related to Teratocarcinoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053778.8BMP2, CRABP1, FGF2, RARA, RARB, RARG
2MP:00053808.3BMP2, ENPP2, JUN, LAMB1, NANOG, RARA
3MP:00028737.8BMP2, CRABP1, ENPP2, JUN, RARA, RARB

Publications for Teratocarcinoma

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Articles related to Teratocarcinoma:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
A significant association between BDNF promoter methylation and the risk of drug addiction. (26976342)
2016
2
Genetic Variants in ASCT2 Gene are Associated with the Prognosis of Transarterial Chemoembolisation-Treated Early- Stage Hepatocelluar Carcinoma. (25987094)
2015
3
A look behind the scenes: the risk and pathogenesis of primary osteoporosis. (25900210)
2015
4
Successful use of a modified Goeckerman regimen in the treatment of generalized prurigo nodularis. (25497953)
2015
5
Pathophysiology of medication overuse headache-an update. (24117004)
2014
6
Reliability of PAX8 in clinical practice to accurately determine primary site of origin in female pelvic or abdominal lesions. (24857336)
2014
7
Recurrent benign adrenal pheochromocytomas associated with hemihypertrophy. (25136447)
2014
8
Mitochondrial cofactors in Experimental Huntington's Disease: Behavioural, Biochemical and Histological Evaluation. (24393741)
2014
9
Leukodystrophy associated with mitochondrial complex I deficiency due to a novel mutation in the NDUFAF1 gene. (24963768)
2014
10
Increasing Occurrence of Antimicrobial-Resistant Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae Isolates in China. (24099919)
2014
11
Oxidative stress promotes D-GalN/LPS-induced acute hepatotoxicity by increasing glycogen synthase kinase 3I^ activity. (24531650)
2014
12
Dietary plant extracts alleviate diarrhea and alter immune responses of weaned pigs experimentally infected with a pathogenic Escherichia coli. (24045466)
2013
13
Does stress increase the risk of atopic dermatitis in adolescents? results of the Korea Youth Risk Behavior Web-based Survey (KYRBWS-VI). (23940513)
2013
14
Oxidative stress and MAPK involved into ATF2 expression in immortalized human urothelial cells treated by arsenic. (23591579)
2013
15
Pleural infection 55 years after plombage for pulmonary tuberculosis. (23430436)
2013
16
Hairy Cell Leukemia and cutaneous involvement. (22370038)
2012
17
Ivabradine in combination with beta-blocker improves symptoms and quality of life in patients with stable angina pectoris: results from the ADDITIONS study. (22231643)
2012
18
A prediction model of histological chorioamnionitis and funisitis in preterm prelabor rupture of membranes: analyses of multiple proteins in the amniotic fluid. (22372866)
2012
19
Portal vein thrombosis in inflammatory bowel diseases: a single-center case series. (22405175)
2012
20
Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer. (21271559)
2011
21
Calciphylaxis: a still unmet challenge. (21337312)
2011
22
Changing demographics in REM sleep behavior disorder: possible effect of autoimmunity and antidepressants. (21317035)
2011
23
Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA. (21474761)
2011
24
Erlotinib treatment for persistent spontaneous pneumothorax in non-small cell lung cancer: a case report. (22166539)
2010
25
Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity. (20881232)
2010
26
Assessment and management of neurogenic claudication associated with lumbar spinal stenosis in a UK primary care musculoskeletal service: a survey of current practice among physiotherapists. (19796387)
2009
27
Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner. (19297428)
2009
28
The CLCA gene family: putative therapeutic target for respiratory diseases. (19530997)
2009
29
Morbid obesity in an adolescent with Prader-Willi syndrome. (19543650)
2009
30
WT1 and Bcl2 expression in melanocytic lesions of the conjunctiva: an immunohistochemical study of 123 cases. (19667332)
2009
31
Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature. (19696615)
2009
32
Juvenile psoriatic arthritis: bathwater or baby? (19738207)
2009
33
Mechanism of basic calcium phosphate crystal-stimulated cyclo-oxygenase-1 up-regulation in osteoarthritic synovial fibroblasts. (18448481)
2008
34
Inflammatory cytokine signaling in insulin producing beta-cells enhances the colocalization correlation coefficient between L-type voltage-dependent calcium channel and calcium-sensing receptor. (18636168)
2008
35
Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors. (17662948)
2007
36
Our experience with transanal endorectal pull-through in Hirschsprung's disease. (17968790)
2007
37
Archaeal signal peptidases. (17259602)
2007
38
Glutamate receptor changes associated with transient anoxia/hypoglycaemia in hippocampal slice cultures. (16519662)
2006
39
Response to arachidonate 5-lipoxygenase variants in atherosclerosis, obesity, and bone traits. (16690886)
2006
40
p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2. (15318938)
2004
41
The non-invasive diagnosis of precancerous changes of stomach mucosa. (15631316)
2004
42
Development of proximal calciphylaxis with penile involvement after parathyroidectomy in a patient on hemodialysis. (14964582)
2004
43
The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. (11136707)
2001
44
Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination. (10518560)
1999
45
Prolactin-producing cells differentiate from G0/G1-arrested somatotrophs in vitro: an analysis of cell cycle phases and mammotroph differentiation. (10395227)
1998
46
Distribution of glutamate transporter subtypes during human brain development. (9375691)
1997
47
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. (9398840)
1997
48
Incidence of humoral immunodeficiency in children with recurrent infections]. (8834839)
1995
49
Studies on the cardiac actions of flosequinan in vitro. (1324061)
1992
50
A method to assess histamine-induced cyclic AMP production in isolated gastric mucosal cells from human biopsies. (1682955)
1991

Variations for Teratocarcinoma

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Expression for genes affiliated with Teratocarcinoma

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Search GEO for disease gene expression data for Teratocarcinoma.

Pathways for genes affiliated with Teratocarcinoma

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GO Terms for genes affiliated with Teratocarcinoma

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Biological processes related to Teratocarcinoma according to GeneCards Suite gene sharing:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1retinal pigment epithelium developmentGO:000340610.7RARB, RARG
2embryonic eye morphogenesisGO:004804810.6RARB, RARG
3cell migration involved in sprouting angiogenesisGO:000204210.6FGF2, TDGF1
4positive regulation of programmed cell deathGO:004306810.5RARB, RARG
5negative regulation of chondrocyte differentiationGO:003233110.5RARB, RARG
6trachea cartilage developmentGO:006053410.5RARA, RARG
7face developmentGO:006032410.5RARA, RARG
8corticotropin hormone secreting cell differentiationGO:006012810.5BMP2, FGF2
9chondroblast differentiationGO:006059110.5FGF2, RARA
10embryonic hindlimb morphogenesisGO:003511610.4RARB, RARG
11ventricular cardiac muscle cell differentiationGO:005501210.4RARA, RARB
12glandular epithelial cell developmentGO:000206810.3RARA, RARB, RARG
13outflow tract septum morphogenesisGO:000314810.3RARA, RARB
14negative regulation of cartilage developmentGO:006103710.3RARA, RARB, RARG
15steroid hormone mediated signaling pathwayGO:004340110.2RARA, RARB
16growth plate cartilage developmentGO:000341710.1RARB, RARG
17regulation of myelinationGO:003164110.1RARA, RARB, RARG
18bone developmentGO:006034810.0RARA, RARB, RARG
19activation of MAPK activityGO:000018710.0BMP2, FGF2, TDGF1
20multicellular organism growthGO:00352649.9RARA, RARB, RARG
21retinoic acid receptor signaling pathwayGO:00483849.7RARA, RARB, RARG
22negative regulation of apoptotic processGO:00430669.4JUN, RARA, RARB, RARG

Molecular functions related to Teratocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1retinoic acid bindingGO:00019729.8CRABP1, RARA

Sources for Teratocarcinoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet