MCID: TRT005
MIFTS: 15

Teratoma with Malignant Transformation malady

Category: Rare diseases

Aliases & Classifications for Teratoma with Malignant Transformation

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Aliases & Descriptions for Teratoma with Malignant Transformation:

Name: Teratoma with Malignant Transformation 48

Classifications:



Summaries for Teratoma with Malignant Transformation

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NIH Rare Diseases:48 A teratoma with malignant transformation (tmt) is a tumor that develops from germ cells when they grow and divide abnormally, forming a mass.  approximately 6% of teratomas develop into tmts by a process called malignant transformation, when some of the cells in the teratoma become cancerous.  tmts can occur anywhere in the body, but most are located in the testes in men or ovaries in women.  the cause of tmt is unknown.  treatment may include surgery and chemotherapy. last updated: 9/21/2012

MalaCards based summary: Teratoma with Malignant Transformation is related to teratoma and cystic teratoma. Affiliated tissues include testes and ovary.

Related Diseases for Teratoma with Malignant Transformation

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Diseases related to Teratoma with Malignant Transformation via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1teratoma10.4
2cystic teratoma10.1
3adenocarcinoma10.0
4mature teratoma9.9
5mediastinitis9.9
6squamous cell carcinoma9.8
7sacrococcygeal teratoma9.7
8mucinous adenocarcinoma9.7
9cerebritis9.7
10mediastinum teratoma9.7

Graphical network of diseases related to Teratoma with Malignant Transformation:



Diseases related to teratoma with malignant transformation

Symptoms & Phenotypes for Teratoma with Malignant Transformation

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Drugs & Therapeutics for Teratoma with Malignant Transformation

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Drugs for Teratoma with Malignant Transformation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
nivolumabapprovedPhase 2424946414-94-4
Synonyms:
BMS-936558
 
MDX-1106
ONO-4538
nivolumab
2ImmunoglobulinsPhase 26394
3Antibodies, MonoclonalPhase 24039
4AntibodiesPhase 26394

Interventional clinical trials:

idNameStatusNCT IDPhase
1Nivolumab and Ipilimumab in Treating Patients With Rare TumorsRecruitingNCT02834013Phase 2

Search NIH Clinical Center for Teratoma with Malignant Transformation

Genetic Tests for Teratoma with Malignant Transformation

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Anatomical Context for Teratoma with Malignant Transformation

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MalaCards organs/tissues related to Teratoma with Malignant Transformation:

36
Testes, Ovary

Publications for Teratoma with Malignant Transformation

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Articles related to Teratoma with Malignant Transformation:

(show all 31)
idTitleAuthorsYear
1
The Case of an Elderly Male Patient with Unknown Primary Mucinous Adenocarcinoma within Presacral Teratoma (Teratoma with Malignant Transformation). (25874143)
2015
2
Teratoma with malignant transformation: report of three cases and review of the literature. (24908364)
2014
3
Naturally occurring mediastinal teratoma with malignant transformation in an adult male. (24003416)
2013
4
Squamous cell carcinoma occurring in the pelvis after total hysterectomy and bilateral salpingo-oophorectomy for an ovarian mature teratoma with malignant transformation. (23040935)
2012
5
Re: towards the definition of the best management and prognostic factors of teratoma with malignant transformation: a single-institution case series and new proposal. (22494724)
2012
6
Mature cystic teratoma with malignant transformation to adenocarcinoma. (21619995)
2011
7
Towards the definition of the best management and prognostic factors of teratoma with malignant transformation: a single-institution case series and new proposal. (20868391)
2011
8
CT findings of mature cystic teratoma with malignant transformation: comparison with mature cystic teratoma. (21724123)
2011
9
Teratoma with malignant transformation: a case report with pathological, cytogenetic, and immunohistochemistry analysis. (21776193)
2011
10
Non-germ cell tumours arising in germ cell tumours (teratoma with malignant transformation) in men: CT and MR findings. (19056194)
2009
11
An unusual case of giant mediastinal teratoma with malignant transformation. (18573447)
2008
12
Teratoma with malignant transformation in the anterior mediastinum. (18603085)
2008
13
Preoperative diagnosis of mature cystic teratoma with malignant transformation: analysis of imaging findings and clinical and laboratory data. (16924513)
2007
14
Use of the collagen gel droplet embedded drug sensitivity test to determine drug sensitivity against ovarian mature cystic teratoma with malignant transformation to adenocarcinoma: a case report. (17308380)
2007
15
Eyelid metastasis from mediastinal teratoma with malignant transformation. (17851848)
2007
16
Chemotherapy in patients with teratoma with malignant transformation. (17081678)
2007
17
Teratoma with malignant transformation: experiences of the cooperative GPOH protocols MAKEI 83/86/89/96. (17080331)
2006
18
Cerebral mature teratoma with malignant transformation in a 52-year-old man: a case report. (16637568)
2006
19
Poor prognosis of intraoperative rupture of mature cystic teratoma with malignant transformation. (17175475)
2006
20
Chemotherapy for teratoma with malignant transformation. (14645417)
2003
21
Ovarian teratoma with malignant transformation: CT diagnosis. (12034646)
2002
22
Intraperitoneal cancer spread after laparoscopic cystectomy for mature teratoma with malignant transformation. (12013109)
2002
23
Case report: sacrococcygeal teratoma with malignant transformation in an adult female: CT and MRI findings. (12145137)
2002
24
Expression of cyclooxygenase-2 in ovarian mature cystic teratomas with malignant transformation. (11605016)
2001
25
Teratoma with malignant transformation in the anterior mediastinum: a case report. (11752948)
2000
26
A ruptured teratoma with malignant transformation. (10939511)
2000
27
Ovarian mature cystic teratoma with malignant transformation. An interphase cytogenetic study. (9785136)
1998
28
Teratoma with malignant transformation: diverse malignant histologies arising in men with germ cell tumors. (9400455)
1998
29
Testicular teratoma with malignant transformation, presenting as squamous cell carcinoma with metastatic localization in the penile corpus cavernosum. (9043522)
1997
30
Well-differentiated adenocarcinoma arising from mature cystic teratoma of the mediastinum (teratoma with malignant transformation). Report of a surgical case. (8160647)
1994
31
Teratoma with malignant transformation in germ cell tumors in men. (2990657)
1985

Variations for Teratoma with Malignant Transformation

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Expression for genes affiliated with Teratoma with Malignant Transformation

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Search GEO for disease gene expression data for Teratoma with Malignant Transformation.

Pathways for genes affiliated with Teratoma with Malignant Transformation

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GO Terms for genes affiliated with Teratoma with Malignant Transformation

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Sources for Teratoma with Malignant Transformation

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet