MCID: TST014
MIFTS: 54

Testicular Cancer

Categories: Rare diseases, Cancer diseases, Reproductive diseases

Aliases & Classifications for Testicular Cancer

MalaCards integrated aliases for Testicular Cancer:

Name: Testicular Cancer 12 49 36 51 40 3 14
Testicular Neoplasms 41 69
Testicular Malignant Germ Cell Tumor 69
Childhood Neoplasm of the Testis 12
Pediatric Testicular Neoplasm 12
Childhood Testicular Neoplasm 69
Malignant Neoplasm of Testis 69
Carcinoma of the Testis 69
Cancer of the Testes 49
Testicular Carcinoma 51
Testicular Neoplasm 28
Neoplasm of Testis 12
Testicular Tumor 12
Testis Neoplasm 12
Testis Cancer 12

Classifications:



Summaries for Testicular Cancer

MedlinePlus : 40 Testicles, or testes, make male hormones and sperm. They are two egg-shaped organs inside the scrotum, the loose sac of skin behind the penis. You can get cancer in one or both testicles. Testicular cancer mainly affects young men between the ages of 20 and 39. It is also more common in men who Have had abnormal testicle development Have had an undescended testicle Have a family history of the cancer Symptoms include pain, swelling, or lumps in your testicles or groin area. Doctors use a physical exam, lab tests, imaging tests, and a biopsy to diagnose testicular cancer. Most cases can be treated, especially if found early. Treatment options include surgery, radiation, and/or chemotherapy. Regular exams after treatment are important. Treatments may also cause infertility. If you may want children later on, you should consider sperm banking before treatment. NIH: National Cancer Institute

MalaCards based summary : Testicular Cancer, also known as testicular neoplasms, is related to testicular seminoma and cryptorchidism, unilateral or bilateral. An important gene associated with Testicular Cancer is INSL3 (Insulin Like 3), and among its related pathways/superpathways are G alpha (s) signalling events and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Cisplatin and Imiquimod have been mentioned in the context of this disorder. Affiliated tissues include the testicles, testis and bone.

Disease Ontology : 12 A male reproductive system cancer that is located in the testicles.

Wikipedia : 72 Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system.... more...

Related Diseases for Testicular Cancer

Diseases related to Testicular Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 152)
# Related Disease Score Top Affiliating Genes
1 testicular seminoma 31.7 CGA CGB3 TSPY1
2 cryptorchidism, unilateral or bilateral 31.6 AR CGA CGB5 INSL3 RXFP2 SHBG
3 testicular disease 31.4 CGA INSL3
4 teratoma 30.4 AFP CGA CGB3
5 testicular germ cell tumor 30.2 AFP AR STK11
6 nonseminomatous germ cell tumor 30.1 AFP CGB5
7 gynecomastia 29.9 AR CGA SHBG
8 androgen insensitivity syndrome 29.7 AR CGA SHBG
9 hydrocele 29.6 AFP CGA
10 choriocarcinoma 29.5 ALPP CGA CGB3 CGB5
11 seminoma 28.4 AFP ALPP CGA CGB3 CGB5 MAGEA4
12 rete testis neoplasm 12.0
13 testicular cancer, childhood 11.9
14 resistance to bleomycine in the treatment of testicular cancer 11.9
15 testicular microlithiasis 11.3
16 testicular germ cell cancer 11.2
17 embryonal carcinoma 11.0
18 rete testis adenocarcinoma 11.0
19 testis sarcoma 11.0
20 testicular leydig cell tumor 11.0
21 spermatocele 10.9
22 testicular brenner tumor 10.9
23 testis refractory cancer 10.9
24 ovarian mixed germ cell neoplasm 10.5 AFP CGA
25 polyembryoma 10.5 AFP CGA
26 sacrococcygeal teratoma 10.5 AFP CGA
27 malignant sertoli cell tumor 10.5 AFP CGB5
28 triploidy 10.5 AFP CGA
29 corpus luteum cyst 10.5 AFP CGB5
30 extragonadal germ cell cancer 10.5 AFP CGB5
31 tuberculous epididymitis 10.5 AFP CGB3
32 physical disorder 10.4 AFP INSL3 RXFP2
33 47, xxy 10.4 AR SHBG
34 penis agenesis 10.4 AR CGA
35 sertoli-leydig cell tumor 10.4 AFP INSL3
36 mixed germ cell tumor 10.4 AFP CGA CGB3
37 chromosomal triplication 10.4 AFP CGA CGB3
38 placental site trophoblastic tumor 10.3 CGB3 CGB5
39 postmenopausal atrophic vaginitis 10.3 AR SHBG
40 androgen insensitivity, partial 10.3 AR SHBG
41 prostatic adenoma 10.3 AR SHBG
42 hydatidiform mole, recurrent, 1 10.3 CGA CGB3 CGB5
43 ectopic pregnancy 10.3 CGA CGB3 CGB5
44 hermaphroditism 10.3 AR SHBG
45 seborrheic dermatitis 10.3 CGA SHBG
46 alopecia, androgenetic, 1 10.3 AR SHBG
47 complete androgen insensitivity syndrome 10.3 AR CGA SHBG
48 papillary hidradenoma 10.3 AR STK11
49 orofaciodigital syndrome viii 10.3 AFP CGA
50 anorchia 10.2 CGA CGB5 INSL3 RXFP2

Graphical network of the top 20 diseases related to Testicular Cancer:



Diseases related to Testicular Cancer

Symptoms & Phenotypes for Testicular Cancer

Drugs & Therapeutics for Testicular Cancer

Drugs for Testicular Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 305)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
2
Imiquimod Approved, Investigational Phase 4 99011-02-6 57469
3
Methyltestosterone Approved Phase 4,Phase 2,Phase 3 58-18-4 6010
4
Testosterone Approved, Investigational Phase 4,Phase 2,Phase 3 58-22-0 6013
5
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
6 Adjuvants, Immunologic Phase 4,Phase 3,Phase 1,Phase 2
7 interferons Phase 4,Phase 1,Phase 2
8 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3
9 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
10 Hormones Phase 4,Phase 2,Phase 3,Phase 1
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
12 Interferon Inducers Phase 4,Phase 1,Phase 2
13 Anabolic Agents Phase 4,Phase 2,Phase 3
14 Androgens Phase 4,Phase 2,Phase 3
15 Testosterone 17 beta-cypionate Phase 4,Phase 2,Phase 3
16
Testosterone enanthate Phase 4,Phase 2,Phase 3 315-37-7 9416
17 Testosterone undecanoate Phase 4,Phase 2,Phase 3
18 Estradiol 17 beta-cypionate Phase 4,Phase 3
19 Estradiol 3-benzoate Phase 4,Phase 3
20 Estradiol valerate Phase 4,Phase 3 979-32-8
21 Follicle Stimulating Hormone Phase 4
22 Polyestradiol phosphate Phase 4,Phase 3
23
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
24
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
25
Etoposide Approved Phase 3,Phase 2,Phase 1 33419-42-0 36462
26
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
27
Vinblastine Approved Phase 3 865-21-4 241903 13342
28
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
29
Bleomycin Approved, Investigational Phase 3,Phase 2 11056-06-7 5360373
30
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
31
Oxaliplatin Approved, Investigational Phase 3,Phase 2 61825-94-3 43805 6857599 5310940 9887054
32
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
33
Lenograstim Approved, Investigational Phase 2, Phase 3, Phase 1 135968-09-1
34
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
35
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
36
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
37
Ofloxacin Approved Phase 3 82419-36-1 4583
38
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
39
Captopril Approved Phase 3 62571-86-2 44093
40
Palivizumab Approved, Investigational Phase 3 188039-54-5
41
Ribavirin Approved Phase 3 36791-04-5 37542
42
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
43
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
44
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
45
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
46
Caspofungin Approved Phase 3,Phase 2 162808-62-0, 179463-17-3 2826718 468682
47
Diphenhydramine Approved, Investigational Phase 3 58-73-1, 147-24-0 3100
48
Promethazine Approved, Investigational Phase 3 60-87-7 4927
49
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
50
Moxifloxacin Approved, Investigational Phase 3 151096-09-2, 354812-41-2 152946

Interventional clinical trials:

(show top 50) (show all 284)

# Name Status NCT ID Phase Drugs
1 Taste, Smell and Chemotherapy (TASTY) Completed NCT01641172 Phase 4
2 Effect of Topical Imiquimod on Lentigo Maligna Completed NCT01161888 Phase 4 Imiquimod
3 Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters Recruiting NCT03203681 Phase 4 NATESTO® (4.5% nasal testosterone) Nasal Gel
4 Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors Unknown status NCT00002566 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide;ifosfamide;vinblastine sulfate
5 Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle Unknown status NCT00589537 Phase 3
6 Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma Unknown status NCT00004219 Phase 3 granisetron hydrochloride;lerisetron
7 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
8 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
9 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
10 Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors Unknown status NCT00274950 Phase 3 carboplatin;cisplatin;etoposide;ifosfamide;vinblastine sulfate
11 Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular Cancer Completed NCT00003014 Phase 3 carboplatin
12 Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles Completed NCT00324298 Phase 3 cisplatin;etoposide
13 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
14 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Completed NCT00053352 Phase 3 cisplatin;etoposide
15 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
16 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3 supersaturated calcium phosphate rinse
17 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3 levofloxacin
18 Androgen for Leydig Cell Proliferation Completed NCT01206270 Phase 2, Phase 3 Testosterone undecanoate;Castor Oil
19 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
20 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
21 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
22 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
23 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
24 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
25 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
26 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
27 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Completed NCT00716976 Phase 3 sodium thiosulfate
28 Study of Testosterone vs Placebo in Testicular Cancer Survivors Recruiting NCT02991209 Phase 2, Phase 3 Testosterone;Placebos
29 Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer Recruiting NCT02341989 Phase 3 Bleomycin Etoposide and Cisplatin;Carboplatin
30 Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours Recruiting NCT02582697 Phase 3 Bleomycin (active name: Bleomycin Sulfate);Etoposide;Cisplatin;Pegylated G-CSF (Pegfilgrastim);Filgrastim
31 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
32 Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours Active, not recruiting NCT01726374 Phase 3 BEP(500)
33 Hypofractionated, Dose Escalation Radiotherapy for High Risk Adenocarcinoma of the Prostate Active, not recruiting NCT01444820 Phase 3
34 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
35 Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant Terminated NCT00324324 Phase 3 moxifloxacin hydrochloride;Placebo
36 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
37 Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD) Terminated NCT00089141 Phase 3 mycophenolate mofetil;placebo
38 Sorafenib Monotherapy in Inoperable/Recurrent Germ Cell Carcinoma Refractory to Chemotherapy Unknown status NCT00772694 Phase 2 sorafenib
39 Peptide Vaccination in Treating Patients With Esophageal Cancer (STF-II) Unknown status NCT01267578 Phase 2
40 A Study With Peptide Vaccination in Treating Patients With Esophageal Cancer Unknown status NCT00995358 Phase 2
41 Sutent and Radiation as Treatment for Limited Extent Metastatic Cancer Unknown status NCT00463060 Phase 1, Phase 2 sunitinib malate (Sutent)
42 Phase II Study of S-488410 to Treat Non-small Cell Lung Cancer Unknown status NCT01592617 Phase 2 S-488410
43 Safety and Efficacy Study of Epitope Peptide To Treat HLA-A*02 Disease Controlled Advanced Non-small Cell Lung Cancer Unknown status NCT01949701 Phase 1, Phase 2
44 Pazopanib in Advanced and Cisplatin-resistant Germ Cell Tumors Unknown status NCT01743482 Phase 2 Pazopanib
45 Promotora-based Latino Family CVD Risk Reduction Unknown status NCT01714271 Phase 2
46 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
47 Trial of Gemcitabine, Cisplatin, and Ifosfamide in Patients With Relapsed Non-Seminomatous Germ-Cell Tumors Unknown status NCT00127049 Phase 2 gemcitabine, ifosfamide, cisplatin, G-CSF
48 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2 carboplatin;cisplatin;dexamethasone;etoposide;ifosfamide
49 Everolimus in Refractory Testicular Germ Cell Cancer Completed NCT01466231 Phase 2 Everolimus
50 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel

Search NIH Clinical Center for Testicular Cancer

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: testicular neoplasms

Genetic Tests for Testicular Cancer

Genetic tests related to Testicular Cancer:

# Genetic test Affiliating Genes
1 Testicular Neoplasm 28

Anatomical Context for Testicular Cancer

The Foundational Model of Anatomy Ontology organs/tissues related to Testicular Cancer:

18
The Testicles

MalaCards organs/tissues related to Testicular Cancer:

38
Testis, Bone, Bone Marrow, Testes, Lymph Node, T Cells, Lung

Publications for Testicular Cancer

Articles related to Testicular Cancer:

(show top 50) (show all 816)
# Title Authors Year
1
Late relapse in stage I of nonseminomatous germ cell testicular cancer on surveillance. ( 29405722 )
2018
2
Thromboprophylaxis and the route of administration of chemotherapy in testicular cancer patients in German-speaking countries. ( 29417289 )
2018
3
Further investigation of the role of ACYP2 and WFS1 pharmacogenomic variants in the development of cisplatin-induced ototoxicity in testicular cancer patients. ( 29358504 )
2018
4
Onco-testicular sperm extraction (Onco-TESE) from a single testis with metachronous bilateral testicular cancer: a case report. ( 29416867 )
2018
5
Testicular cancer in 2017: Sequencing advances understanding. ( 29256490 )
2018
6
Re: Multi-Institutional Assessment of Adverse Health Outcomes among North American Testicular Cancer Survivors after Modern Cisplatin-Based Chemotherapy. ( 29310185 )
2018
7
Adenomatoid tumor of the testis mimicking malignant testicular cancer on multiparametric ultrasound. ( 29325584 )
2018
8
Non-risk-adapted Surveillance for Stage I Testicular Cancer: Critical Review and Summary. ( 29338978 )
2018
9
Testicular Cancer: Epidemiology, Diagnosis, and Management. ( 29406056 )
2018
10
An X-linked agammaglobulinemia contiguous gene syndrome with metachronous coprimary testicular cancers. ( 29307603 )
2018
11
Re: Singh A<i>et al</i>. Robot-assisted retroperitoneal lymph node dissection: Feasibility and outcome in postchemotherapy residual mass in testicular cancer. Indian J Urol 2017;33:304-9. ( 29345697 )
2018
12
Physical activity and risk of testicular cancer: a systematic review. ( 29444652 )
2018
13
Reply to Christian D. Fankhauser, Nico C. Grossmann, Joerg Beyer, and Thomas Hermanns' Letter to the Editor re: Sophia C. Kamran, Thomas Seisen, Sarah C. Markt, et al. Contemporary treatment patterns and outcomes for clinical stage IS testicular cancer. Eur Urol 2018;73:262-70. ( 29358058 )
2018
14
Hearing loss before and after cisplatin-based chemotherapy in testicular cancer survivors: a longitudinal study. ( 29384420 )
2018
15
Testicular cancer from diagnosis to epigenetic factors. ( 29262668 )
2017
16
Metachronous Testicular Cancer After Orchiectomy: A Rare Case. ( 29333356 )
2017
17
Multidisciplinary management of testicular cancer complicated by thrombosis of the inferior vena cava: a case report. ( 28678675 )
2017
18
Testicular Cancer on the Web-an Appropriate Source of Patient Information in Concordance with the European Association of Urology Guidelines? ( 28776306 )
2017
19
Postnatal risk factors for testicular cancer: The EPSAM case-control study. ( 28699204 )
2017
20
Exploring men's preferred strategies for learning about testicular disorders inclusive of testicular cancer: A qualitative descriptive study. ( 28069149 )
2017
21
Evaluation of sperm DNA quality in men presenting with testicular cancer and lymphoma using alkaline and neutral Comet assays. ( 28950441 )
2017
22
Cancer Death Risk Related to Radiation Exposure from Computed Tomography Scanning Among Testicular Cancer Patients. ( 28179338 )
2017
23
Re: Predictors of Sperm Recovery after Cryopreservation in Testicular Cancer. ( 28505905 )
2017
24
Reimbursements and frequency of tests in privately insured testicular cancer patients in the United States: Implications to national guidelines. ( 28479767 )
2017
25
Cancer-Related Worry and Physical Well-Being in the Context of Perceived Stress in Young Adults with Testicular Cancer. ( 28128672 )
2017
26
Testicular cancer: Origin and evolution of TGCTs. ( 27922034 )
2017
27
Environmental Factors Affecting Growth and Occurrence of Testicular Cancer in Childhood: An Overview of the Current Epidemiological Evidence. ( 28067779 )
2017
28
Effects of high-intensity aerobic interval training on cardiovascular disease risk in testicular cancer survivors: A phase 2 randomized controlled trial. ( 28708930 )
2017
29
Recurrent Masses after Testicular Cancer: Growing Teratoma Syndrome. A Case Report and Review of the Literature. ( 29279691 )
2017
30
Early life risk factors for testicular cancer: a case-cohort study based on the Copenhagen School Health Records Register. ( 28080187 )
2017
31
Testicular cancer patients undergoing cisplatin based chemotherapy exhibit temporary olfactory threshold scores changes. ( 28429112 )
2017
32
Spontaneous CD4+ and CD8+ T-cell responses directed against cancer testis antigens are present in the peripheral blood of testicular cancer patients. ( 28555838 )
2017
33
Role of Pannexin1 channels in the resistance of I-10 testicular cancer cells to cisplatin mediated by ATP/IP3 pathway. ( 28780469 )
2017
34
Adjuvant chemotherapy and follow-up for recurrences in localized testicular cancer. ( 28481147 )
2017
35
New SNPs from Testicular Cancer GWAS. ( 28687564 )
2017
36
Fertility preservation of patients with testicular cancer. ( 29259474 )
2017
37
Testicular Tumour Size and Rete Testis Invasion as Prognostic Factors for the Risk of Relapse of Clinical Stage I Seminoma Testis Patients Under Surveillance: a Systematic Review by the Testicular Cancer Guidelines Panel. ( 29100813 )
2017
38
Stomach Cancer Following Hodgkin Lymphoma, Testicular Cancer and Cervical Cancer: A Pooled Analysis of Three International Studies with a Focus on Radiation Effects. ( 28118119 )
2017
39
Practice Makes Perfect: The Rest of the Story in Testicular Cancer as a Model Curable Neoplasm. ( 28854068 )
2017
40
Excess of Radiation Burden for Young Testicular Cancer Patients using Automatic Exposure Control and Contrast Agent on Whole-body Computed Tomography Imaging. ( 28740460 )
2017
41
Predictive Factors for Developing Venous Thrombosis during Cisplatin-Based Chemotherapy in Testicular Cancer. ( 28514776 )
2017
42
Re: Safety and Early Oncologic Effectiveness of Primary Robotic Retroperitoneal Lymph Node Dissection for Nonseminomatous Germ Cell Testicular Cancer. ( 29370608 )
2017
43
Deep exploration of the immune infiltrate and outcome prediction in testicular cancer by quantitative multiplexed immunohistochemistry and gene expression profiling. ( 28507813 )
2017
44
Multi-Institutional Assessment of Adverse Health Outcomes Among North American Testicular Cancer Survivors After Modern Cisplatin-Based Chemotherapy. ( 28240972 )
2017
45
A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention). ( 28673265 )
2017
46
Semen quality before cryopreservation and after thawing in 543 patients with testicular cancer. ( 28333030 )
2017
47
Management of testicular cancer: NYU case of the month, March 2017. ( 28522933 )
2017
48
Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer. ( 28448657 )
2017
49
Gene discovery will help identify testicular cancer risk. ( 28699433 )
2017
50
Impact of hospital case volume on testicular cancer outcomes and practice patterns. ( 28935185 )
2017

Variations for Testicular Cancer

Copy number variations for Testicular Cancer from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 61546 12 1 35400000 Gain Testicular cancer
2 202070 5 76900000 102800000 Loss Testicular cancer
3 217038 7 1 158821424 Gain Testicular cancer
4 237464 8 23300000 146274826 Gain Testicular cancer
5 262544 X 37500000 154913754 Gain Testicular cancer
6 262545 X 37500000 154913754 Gain Testicular cancer
7 266960 Y 174481503 174538309 Deletion AZF Testicular cancer

Expression for Testicular Cancer

Search GEO for disease gene expression data for Testicular Cancer.

Pathways for Testicular Cancer

GO Terms for Testicular Cancer

Biological processes related to Testicular Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 spermatogenesis GO:0007283 9.55 AR INSL3 PRSS21 STK11 TSPY1
2 cell-cell signaling GO:0007267 9.35 AR CGA CGB3 CGB5 INSL3
3 sex differentiation GO:0007548 9.32 AR TSPY1
4 female gamete generation GO:0007292 9.26 CGB3 CGB5
5 peptide hormone processing GO:0016486 8.8 CGA CGB3 CGB5

Molecular functions related to Testicular Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.13 CGA CGB3 INSL3
2 androgen binding GO:0005497 8.62 AR SHBG

Sources for Testicular Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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