MCID: TST014
MIFTS: 53

Testicular Cancer malady

Categories: Rare diseases, Cancer diseases, Reproductive diseases

Aliases & Classifications for Testicular Cancer

Aliases & Descriptions for Testicular Cancer:

Name: Testicular Cancer 12 50 29 52 41 3 14
Testicular Neoplasms 42 69
Testicular Malignant Germ Cell Tumor 69
Childhood Neoplasm of the Testis 12
Pediatric Testicular Neoplasm 12
Childhood Testicular Neoplasm 69
Malignant Neoplasm of Testis 69
Carcinoma of the Testis 69
Cancer of the Testes 50
Testicular Carcinoma 52
Neoplasm of Testis 12
Testicular Tumor 12
Testis Neoplasm 12
Testis Cancer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2998
ICD10 33 C62 C62.9 C62.90
ICD9CM 35 186
MeSH 42 D013736

Summaries for Testicular Cancer

MedlinePlus : 41 testicles, or testes, make male hormones and sperm. they are two egg-shaped organs inside the scrotum, the loose sac of skin behind the penis. you can get cancer in one or both testicles. testicular cancer mainly affects young men between the ages of 20 and 39. it is also more common in men who have had abnormal testicle development have had an undescended testicle have a family history of the cancer symptoms include pain, swelling, or lumps in your testicles or groin area. doctors use a physical exam, lab tests, imaging tests, and a biopsy to diagnose testicular cancer. most cases can be treated, especially if found early. treatment options include surgery, radiation, and/or chemotherapy. regular exams after treatment are important. treatments may also cause infertility. if you may want children later on, you should consider sperm banking before treatment. nih: national cancer institute

MalaCards based summary : Testicular Cancer, also known as testicular neoplasms, is related to mature teratoma and rete testis neoplasm. An important gene associated with Testicular Cancer is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors and Nongenotropic Androgen signaling. The drugs Cisplatin and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include testis, testes and lymph node.

Disease Ontology : 12 A male reproductive system cancer that is located in the testicles.

Wikipedia : 71 Testicular cancer is cancer that develops in the testicles, a part of the male reproductive... more...

Related Diseases for Testicular Cancer

Diseases related to Testicular Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 120)
id Related Disease Score Top Affiliating Genes
1 mature teratoma 29.5 ALPP AR DMRT1
2 rete testis neoplasm 11.9
3 testicular cancer, childhood 11.8
4 resistance to bleomycine in the treatment of testicular cancer 11.8
5 cryptorchidism 11.2
6 testicular microlithiasis 11.2
7 testicular germ cell cancer 11.1
8 embryonal carcinoma 10.9
9 rete testis adenocarcinoma 10.9
10 testis sarcoma 10.9
11 testicular leydig cell tumor 10.8
12 testicular brenner tumor 10.8
13 testicular disease 10.8
14 testis refractory cancer 10.7
15 renal pelvis transitional cell carcinoma 10.3 AFP CGA
16 pontine hemorrhage 10.3 AFP CGA
17 severe combined immunodeficiency 10.3 AFP CGA
18 infiltrating renal pelvis transitional cell carcinoma 10.3 AFP CGB5
19 dementia 10.3 AFP CGB5
20 trypanosomiasis, human east-african 10.3 AFP CGA
21 bagassosis 10.3 AFP CGB3
22 true unicornuate uterus 10.3 AFP CGA CGB3
23 microcephaly, seizures, and developmental delay 10.2 CGA CGB3 CGB5
24 novak syndrome 10.2 AFP CGB5
25 parameningeal embryonal rhabdomyosarcoma 10.2 CGA CGB3 CGB5
26 intraventricular meningioma 10.2 AR CGA SHBG
27 dystonia-parkinsonism, x-linked 10.2 AR SHBG
28 atopic dermatitis 10.2 AFP CGA CGB3
29 congenital articular rigidity 10.2 AR CGA SHBG
30 hypospadias 1, x-linked 10.2 AR CGA SHBG
31 atrophic rhinitis 10.2 AFP CGB5
32 capillary disease 10.2 AR CGA SHBG
33 retroperitoneal sarcoma 10.2 AZF1 CGA SHBG
34 periodic fever, aphthous stomatitis, pharyngitis and adenitis 10.2 AR CGA
35 tetrasomy x 10.2 CGA TSPY1
36 farmer's lung 10.1 CGB3 DMRT1 SHBG
37 antisynthetase syndrome 10.1 CGA CGB5 INSL3
38 prostate cancer, hereditary, x-linked 1 10.1 AFP AR DMRT1 STK11
39 ulceroglandular tularemia 10.1 AR SHBG
40 chromosome 11q duplication 10.1 AFP CGA
41 adult teratoma 10.0 AFP ALPP
42 seminoma 10.0
43 gaucher's disease 10.0 AR AZF1 INSL3 SHBG
44 prostatitis 9.9
45 ovarian mucinous cystadenocarcinoma 9.9 ALPP CGA CGB3 CGB5
46 encephalitis 9.9
47 infertility 9.9
48 teratoma 9.9
49 malignant teratocarcinosarcoma 9.8 AFP ALPP AR CGA CGB5
50 lymphoma 9.8

Graphical network of the top 20 diseases related to Testicular Cancer:



Diseases related to Testicular Cancer

Symptoms & Phenotypes for Testicular Cancer

Drugs & Therapeutics for Testicular Cancer

Drugs for Testicular Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 352)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
2
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
3
Imiquimod Approved, Investigational Phase 4 99011-02-6 57469
4
Leuprolide Approved, Investigational Phase 4,Phase 2 53714-56-0 3911 657181
5 Adjuvants, Immunologic Phase 4,Phase 3,Phase 1,Phase 2
6 interferons Phase 4,Phase 1,Phase 2
7 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
8 Antiemetics Phase 4,Phase 3,Phase 2
9 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
10 Autonomic Agents Phase 4,Phase 3,Phase 2
11 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1
12 Dexamethasone 21-phosphate Phase 4,Phase 3,Phase 2,Phase 1
13 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1 1177-87-3
14 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
15 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
16 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
17 Hormones Phase 4,Phase 2,Phase 3,Phase 1
18 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
19 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
20 Interferon Inducers Phase 4,Phase 1,Phase 2
21 Fertility Agents Phase 4,Phase 2
22 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2
23
protease inhibitors Phase 4,Phase 3,Phase 2
24
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
25
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
26
Etoposide Approved Phase 3,Phase 2,Phase 1,Early Phase 1 33419-42-0 36462
27
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
28
Vinblastine Approved Phase 3 865-21-4 13342 241903
29
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
30
Bleomycin Approved Phase 3,Phase 2 11056-06-7 5360373
31
Mechlorethamine Approved Phase 3,Phase 1,Phase 2 51-75-2 4033
32
Oxaliplatin Approved, Investigational Phase 3,Phase 2 61825-94-3 5310940 9887054 6857599, 9887054 43805
33
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
34
Lenograstim Approved Phase 2, Phase 3, Phase 1 135968-09-1
35
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
36
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
37
Ofloxacin Approved Phase 3 82419-36-1 4583
38
Methyltestosterone Approved Phase 2, Phase 3 58-18-4 6010
39
Testosterone Approved, Investigational Phase 2, Phase 3 58-22-0 6013
40
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
41
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
42
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
43
Caspofungin Approved Phase 3,Phase 2 179463-17-3, 162808-62-0 468682 2826718
44
Palivizumab Approved, Investigational Phase 3 188039-54-5
45
Ribavirin Approved Phase 3 36791-04-5 37542
46
Fluconazole Approved Phase 3 86386-73-4 3365
47
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
48
Captopril Approved Phase 3 62571-86-2 44093
49 Sodium thiosulfate Approved Phase 3
50
Asparaginase Approved Phase 3 9015-68-3

Interventional clinical trials:

(show top 50) (show all 351)
id Name Status NCT ID Phase
1 Taste, Smell and Chemotherapy (TASTY) Completed NCT01641172 Phase 4
2 Effect of Topical Imiquimod on Lentigo Maligna Completed NCT01161888 Phase 4
3 Efficacy and Safety Study of ELIGARD 22.5mg With Prostate Cancer Completed NCT01511874 Phase 4
4 Prevention of Cisplatin-Induced Hearing Loss by Intratympanic Dexamethasone Treatment Completed NCT01372904 Phase 4
5 Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors Unknown status NCT00002566 Phase 3
6 Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle Unknown status NCT00589537 Phase 3
7 Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma Unknown status NCT00004219 Phase 3
8 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3
9 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3
10 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
11 Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors Unknown status NCT00274950 Phase 3
12 Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular Cancer Completed NCT00003014 Phase 3
13 Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles Completed NCT00324298 Phase 3
14 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3
15 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3
16 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3
17 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3
18 Androgen for Leydig Cell Proliferation Completed NCT01206270 Phase 2, Phase 3
19 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3
20 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3
21 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3
22 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3
23 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3
24 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3
25 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3
26 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
27 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Completed NCT00716976 Phase 3
28 Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia Completed NCT00002816 Phase 3
29 Ondansetron With or Without Dexamethasone to Prevent Vomiting in Patients Receiving Radiation Therapy to the Upper Abdomen Completed NCT00016380 Phase 3
30 Dexamethasone Compared With Prednisone During Induction Therapy and MTX With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed NCT00075725 Phase 3
31 Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia Completed NCT00005945 Phase 3
32 Effectiveness of an Abstinence-Only HIV/Sexually Transmitted Disease Risk-Reduction Intervention for Young African-American Adolescents Completed NCT00640653 Phase 2, Phase 3
33 Study of Testosterone vs Placebo in Testicular Cancer Survivors Recruiting NCT02991209 Phase 2, Phase 3
34 Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer Recruiting NCT02341989 Phase 3
35 Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours Recruiting NCT02582697 Phase 3
36 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3
37 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3
38 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Recruiting NCT02883049 Phase 3
39 Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours Active, not recruiting NCT01726374 Phase 3
40 Hypofractionated, Dose Escalation Radiotherapy for High Risk Adenocarcinoma of the Prostate Active, not recruiting NCT01444820 Phase 3
41 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Active, not recruiting NCT00053352 Phase 3
42 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Active, not recruiting NCT00408005 Phase 3
43 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3
44 Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant Terminated NCT00324324 Phase 3
45 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3
46 Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD) Terminated NCT00089141 Phase 3
47 Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia Terminated NCT00002961 Phase 3
48 Sorafenib Monotherapy in Inoperable/Recurrent Germ Cell Carcinoma Refractory to Chemotherapy Unknown status NCT00772694 Phase 2
49 Study of Gemcitabine, Oxaliplatin, and Paclitaxel in Patients With Refractory Germ Cell Carcinoma Unknown status NCT00183820 Phase 2
50 A Study With Peptide Vaccination in Treating Patients With Esophageal Cancer Unknown status NCT00995358 Phase 2

Search NIH Clinical Center for Testicular Cancer

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: testicular neoplasms

Genetic Tests for Testicular Cancer

Genetic tests related to Testicular Cancer:

id Genetic test Affiliating Genes
1 Testicular Neoplasm 29

Anatomical Context for Testicular Cancer

MalaCards organs/tissues related to Testicular Cancer:

39
Testis, Testes, Lymph Node, Skin, Prostate, Lung, Breast

The Foundational Model of Anatomy Ontology organs/tissues related to Testicular Cancer:

18
The Testicles

Publications for Testicular Cancer

Articles related to Testicular Cancer:

(show top 50) (show all 771)
id Title Authors Year
1
Exploring men's preferred strategies for learning about testicular disorders inclusive of testicular cancer: A qualitative descriptive study. ( 28069149 )
2017
2
Testicular cancer patients undergoing cisplatin based chemotherapy exhibit temporary olfactory threshold scores changes. ( 28429112 )
2017
3
Testicular cancer: Origin and evolution of TGCTs. ( 27922034 )
2017
4
Reporting and Staging of Testicular Germ Cell Tumors: The International Society of Urological Pathology (ISUP) Testicular Cancer Consultation Conference Recommendations. ( 28368923 )
2017
5
Early life risk factors for testicular cancer: a case-cohort study based on the Copenhagen School Health Records Register. ( 28080187 )
2017
6
Re: PET/Computed Tomography in Renal, Bladder, and Testicular Cancer. ( 27979571 )
2017
7
Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer. ( 28448657 )
2017
8
Cancer Death Risk Related to Radiation Exposure from Computed Tomography Scanning Among Testicular Cancer Patients. ( 28179338 )
2017
9
Cancer-Related Worry and Physical Well-Being in the Context of Perceived Stress in Young Adults with Testicular Cancer. ( 28128672 )
2017
10
Environmental Factors Affecting Growth and Occurrence of Testicular Cancer in Childhood: An Overview of the Current Epidemiological Evidence. ( 28067779 )
2017
11
Metastatic testicular cancer, a Horner's syndrome and brachial plexopathy. ( 28472531 )
2017
12
Stomach Cancer Following Hodgkin Lymphoma, Testicular Cancer and Cervical Cancer: A Pooled Analysis of Three International Studies with a Focus on Radiation Effects. ( 28118119 )
2017
13
Midline Extraperitoneal Approach to Retroperitoneal Lymph Node Dissection in Testicular Cancer: Minimizing Surgical Morbidity. ( 28325537 )
2017
14
Semen quality before cryopreservation and after thawing in 543 patients with testicular cancer. ( 28333030 )
2017
15
Predictive Factors for Developing Venous Thrombosis during Cisplatin-Based Chemotherapy in Testicular Cancer. ( 28514776 )
2017
16
Reimbursements and frequency of tests in privately insured testicular cancer patients in the United States: Implications to national guidelines. ( 28479767 )
2017
17
Mildly elevated serum alpha-fetoprotein (AFP) among patients with testicular cancer may not be associated with residual cancer or need for treatment. ( 28137740 )
2017
18
Re: Predictors of Sperm Recovery after Cryopreservation in Testicular Cancer. ( 28505905 )
2017
19
Multi-Institutional Assessment of Adverse Health Outcomes Among North American Testicular Cancer Survivors After Modern Cisplatin-Based Chemotherapy. ( 28240972 )
2017
20
Management of testicular cancer: NYU case of the month, March 2017. ( 28522933 )
2017
21
Assessment of Volumetric versus Manual Measurement in Disseminated Testicular Cancer; No Difference in Assessment between Non-Radiologists and Genitourinary Radiologist. ( 28081195 )
2017
22
Sperm aneuploidy after testicular cancer treatment: data from a prospective multicenter study performed within the French Centre d'A8tude et de Conservation des Oeufs et du Sperme network. ( 28069184 )
2017
23
Deep exploration of the immune infiltrate and outcome prediction in testicular cancer by quantitative multiplexed immunohistochemistry and gene expression profiling. ( 28507813 )
2017
24
Adjuvant chemotherapy and follow-up for recurrences in localized testicular cancer. ( 28481147 )
2017
25
Re: Subfertility Increases Risk of Testicular Cancer: Evidence from Population-Based Semen Samples. ( 27479426 )
2016
26
Paratesticular Metastasis of a Clear-Cell Renal-Cell Carcinoma With Renal Vein Thrombus Mimicking Primary Testicular Cancer. ( 27450513 )
2016
27
Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death. ( 26024393 )
2016
28
Efficacy and safety of gemcitabine, oxaliplatin, and paclitaxel in cisplatin-refractory germ cell cancer in routine care-Registry data from an outcomes research project of the German Testicular Cancer Study Group. ( 26699830 )
2016
29
Andrological complications following retroperitoneal lymphnode dissection for testicular cancer: a narrative review. ( 27879966 )
2016
30
Testosterone Deficiency and Bone Metabolism Damage in Testicular Cancer Survivors. ( 27489147 )
2016
31
Conditional Risk of Relapse in Surveillance for Clinical Stage I Testicular Cancer. ( 27527805 )
2016
32
Predictors of spermatogenesis in radical orchiectomy specimen and potential implications for patients with testicular cancer. ( 27005273 )
2016
33
Preorchiectomy Leydig Cell Dysfunction in Patients With Testicular Cancer. ( 27524512 )
2016
34
Genetic changes associated with testicular cancer susceptibility. ( 27899190 )
2016
35
Re: A Comparative Analysis of Robotic vs Laparoscopic Retroperitoneal Lymph Node Dissection for Testicular Cancer. ( 27597070 )
2016
36
Association between Testicular Cancer and Epididymoorchitis: A Population-Based Case-Control Study. ( 26975877 )
2016
37
Testicular Cancer and Testicular Self-Examination; Knowledge, Attitudes and Practice in Final Year Medical Students in Nigeria ( 28032730 )
2016
38
Testosterone deficiency in testicular cancer survivors - a systematic review and meta-analysis. ( 27009402 )
2016
39
Testicular microlithiasis and testicular cancer: review of the literature. ( 27007613 )
2016
40
Management of Pelvic Metastases in Patients With Testicular Cancer. ( 27840253 )
2016
41
Androgen suppresses testicular cancer cell growth in vitro and in vivo. ( 27144435 )
2016
42
Regulatory network of microRNAs and genes in testicular cancer. ( 27900048 )
2016
43
Variation in the HFE gene is associated with the development of bleomycin-induced pulmonary toxicity in testicular cancer patients. ( 27033261 )
2016
44
Long-term health effects among testicular cancer survivors. ( 27169992 )
2016
45
Ongoing Clinical Trials in Testicular Cancer: The TIGER Trial. ( 27614956 )
2016
46
Resident Involvement in Radical Inguinal Orchiectomy for Testicular Cancer Does Not Adversely Impact Perioperative Outcomes - A Retrospective Study. ( 27577733 )
2016
47
Adherence to National Comprehensive Cancer Network Guidelines for Testicular Cancer. ( 27663460 )
2016
48
Epidemiology of Testicular Cancer in Oklahoma and the United States. ( 27885307 )
2016
49
Treatment of stage I seminoma, with one course of adjuvant carboplatin or surveillance, risk-adapted recommendations implementing patient autonomy: a report from the Swedish and Norwegian Testicular Cancer Group (SWENOTECA). ( 27052649 )
2016
50
Overall Survival After Whole-Brain Radiation Therapy for Intracerebral Metastases from Testicular Cancer. ( 27630334 )
2016

Variations for Testicular Cancer

Copy number variations for Testicular Cancer from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 61546 12 1 35400000 Gain Testicular cancer
2 202070 5 76900000 102800000 Loss Testicular cancer
3 217038 7 1 158821424 Gain Testicular cancer
4 237464 8 23300000 146274826 Gain Testicular cancer
5 262544 X 37500000 154913754 Gain Testicular cancer
6 262545 X 37500000 154913754 Gain Testicular cancer
7 266960 Y 174481503 174538309 Deletion AZF Testicular cancer

Expression for Testicular Cancer

Search GEO for disease gene expression data for Testicular Cancer.

Pathways for Testicular Cancer

GO Terms for Testicular Cancer

Biological processes related to Testicular Cancer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 spermatogenesis GO:0007283 9.65 AR DMRT1 INSL3 STK11 TSPY1
2 cell-cell signaling GO:0007267 9.55 AR CGA CGB3 CGB5 INSL3
3 female gamete generation GO:0007292 9.32 CGB3 CGB5
4 sex differentiation GO:0007548 9.13 AR DMRT1 TSPY1
5 peptide hormone processing GO:0016486 8.8 CGA CGB3 CGB5

Molecular functions related to Testicular Cancer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.13 CGA CGB3 INSL3
2 androgen binding GO:0005497 8.62 AR SHBG

Sources for Testicular Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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