MCID: TST016
MIFTS: 23

Testicular Granulosa Cell Tumor

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Testicular Granulosa Cell Tumor

MalaCards integrated aliases for Testicular Granulosa Cell Tumor:

Name: Testicular Granulosa Cell Tumor 12 14 69
Granulosa Cell Tumor of Testis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5331
NCIt 47 C6357
UMLS 69 C1336709

Summaries for Testicular Granulosa Cell Tumor

MalaCards based summary : Testicular Granulosa Cell Tumor, also known as granulosa cell tumor of testis, is related to adult type testicular granulosa cell tumor and juvenile type testicular granulosa cell tumor. An important gene associated with Testicular Granulosa Cell Tumor is CSH1 (Chorionic Somatomammotropin Hormone 1). The drugs Paclitaxel and Bleomycin have been mentioned in the context of this disorder. Affiliated tissues include testis, endothelial and ovary.

Related Diseases for Testicular Granulosa Cell Tumor

Diseases in the Testicular Granulosa Cell Tumor family:

Juvenile Type Testicular Granulosa Cell Tumor Adult Type Testicular Granulosa Cell Tumor

Diseases related to Testicular Granulosa Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
id Related Disease Score Top Affiliating Genes
1 adult type testicular granulosa cell tumor 12.3
2 juvenile type testicular granulosa cell tumor 12.2
3 childhood pleomorphic rhabdomyosarcoma 10.5 AFP WT1
4 congenital pulmonary alveolar proteinosis 10.5 AFP WT1
5 ovary neuroendocrine neoplasm 10.5 AFP WT1
6 testicular pure germ cell tumor 10.5 CSH1 CSH2
7 testicular malignant germ cell cancer 10.4 CSH1 CSH2
8 lung benign neoplasm 10.4 CD99 WT1
9 nasal cavity squamous cell carcinoma 10.4 AFP WT1
10 urethral obstruction sequence 10.4 AFP CEACAM5
11 clear cell variant infiltrating bladder urothelial carcinoma 10.4 AFP CEACAM5
12 intestine carcinoma in situ 10.4 AFP CEACAM5
13 nodular medulloblastoma 10.4 AFP CEACAM5
14 epidermolytic acanthoma 10.4 CSH1 CSH2
15 varicocele 10.4 AFP CEACAM5
16 testicular trophoblastic tumor 10.4 AFP CEACAM5
17 pigmented villonodular synovitis 10.4 AFP CEACAM5
18 ischemia 10.4 AFP WT1
19 sphenoid sinus squamous cell carcinoma 10.4 AFP CEACAM5
20 placental site trophoblastic tumor 10.4 CSH1 CSH2
21 hypogonadism 10.4 AFP WT1
22 tricuspid valve insufficiency 10.4 AFP CEACAM5
23 kallmann syndrome 10.3 CEACAM5 WT1
24 juxtacortical osteosarcoma 10.3 CD99 WT1
25 urethral villous adenoma 10.3 AFP CEACAM5
26 epidermolysis bullosa, junctional, herlitz type 10.3 AFP CEACAM5
27 anterolateral myocardial infarction 10.3 AFP CEACAM5
28 necrotic uveal melanoma 10.3 AFP CSH1
29 peripheral nervous system disease 10.3 CSH1 CSH2
30 female breast axillary tail cancer 10.3 CD99 CEACAM5
31 lobular neoplasia 10.3 CD99 CEACAM5
32 childhood ovarian endodermal sinus tumor 10.3 CEACAM5 WT1
33 peritoneal serous adenocarcinoma 10.3 AFP CEACAM5
34 avian influenza 10.3 CEACAM5 WT1
35 dextrocardia with situs inversus 10.2 CD99 WT1
36 sleep disorder 10.2 AFP CEACAM5
37 dental caries 10.2 CEACAM5 WT1
38 nasal cavity disease 10.2 CEACAM5 WT1
39 gestational choriocarcinoma 10.2 CD99 WT1
40 spondylolysis 10.1 CSH1 CSH2
41 testicular germ cell cancer 10.1 AFP CSH1 CSH2
42 articulation disorder 10.1 AFP CSH1 CSH2
43 thoracic outlet syndrome 10.1 AFP CSH1 CSH2
44 breast disease 10.1 AFP CSH1 CSH2
45 ectodermal dysplasia with natal teeth, turnpenny type 10.1 AFP CEACAM5
46 schnitzler syndrome 10.1 MLANA WT1
47 central nervous system disease 10.0 AFP CD99
48 cutaneous liposarcoma 10.0 MLANA WT1
49 malignant peritoneal solitary fibrous tumor 10.0 AFP CEACAM5 WT1
50 mesothelioma, somatic 10.0 CEACAM5 WT1

Graphical network of the top 20 diseases related to Testicular Granulosa Cell Tumor:



Diseases related to Testicular Granulosa Cell Tumor

Symptoms & Phenotypes for Testicular Granulosa Cell Tumor

Drugs & Therapeutics for Testicular Granulosa Cell Tumor

Drugs for Testicular Granulosa Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
2
Bleomycin Approved Phase 2 11056-06-7 5360373
3
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
4
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
5
Etoposide Approved Phase 2 33419-42-0 36462
6
Bevacizumab Approved, Investigational Phase 2 216974-75-3
7 Albumin-Bound Paclitaxel Phase 2
8 Antimitotic Agents Phase 2
9 Antineoplastic Agents, Phytogenic Phase 2
10 Anti-Bacterial Agents Phase 2
11 Antibiotics, Antitubercular Phase 2
12 Etoposide phosphate Phase 2
13 Topoisomerase Inhibitors Phase 2
14 Angiogenesis Inhibitors Phase 2
15 Angiogenesis Modulating Agents Phase 2
16 Antibodies Phase 2
17 Antibodies, Monoclonal Phase 2
18 Endothelial Growth Factors Phase 2
19 Immunoglobulins Phase 2
20 Mitogens Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Paclitaxel in Treating Patients With Ovarian Stromal Cancer Completed NCT00006227 Phase 2 Paclitaxel
2 Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors Recruiting NCT01042522 Phase 2 Carboplatin;Cisplatin;Etoposide Phosphate;Paclitaxel
3 Bevacizumab in Treating Patients With Recurrent Sex Cord-Stromal Tumors of the Ovary Active, not recruiting NCT00748657 Phase 2
4 International Ovarian & Testicular Stromal Tumor Registry Recruiting NCT01970696

Search NIH Clinical Center for Testicular Granulosa Cell Tumor

Genetic Tests for Testicular Granulosa Cell Tumor

Anatomical Context for Testicular Granulosa Cell Tumor

MalaCards organs/tissues related to Testicular Granulosa Cell Tumor:

39
Testis, Endothelial, Ovary

Publications for Testicular Granulosa Cell Tumor

Articles related to Testicular Granulosa Cell Tumor:

id Title Authors Year
1
Adult testicular granulosa cell tumor: a review of the literature for clinicopathologic predictors of malignancy. ( 21204721 )
2011
2
Response to antiangiogenesis therapy in a patient with advanced adult-type testicular granulosa cell tumor. ( 19777766 )
2009
3
Testicular granulosa cell tumor, adult type. ( 18723972 )
2008
4
Testicular granulosa cell tumor of adult type: a new case and a review of the literature. ( 17628299 )
2007
5
Adult-type testicular granulosa cell tumor: case report and review of the literature. ( 17095056 )
2006
6
Testicular granulosa cell tumor of the adult type. ( 1536615 )
1992

Variations for Testicular Granulosa Cell Tumor

Expression for Testicular Granulosa Cell Tumor

Search GEO for disease gene expression data for Testicular Granulosa Cell Tumor.

Pathways for Testicular Granulosa Cell Tumor

GO Terms for Testicular Granulosa Cell Tumor

Sources for Testicular Granulosa Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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