MCID: TST007
MIFTS: 26

Testicular Infarct malady

Categories: Reproductive diseases

Aliases & Classifications for Testicular Infarct

Aliases & Descriptions for Testicular Infarct:

Name: Testicular Infarct 12 14
Infarction of Testis 12 69
Testicular Infarction 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5104
NCIt 47 C27617
SNOMED-CT 64 33793000
UMLS 69 C0392041

Summaries for Testicular Infarct

MalaCards based summary : Testicular Infarct, also known as infarction of testis, is related to angiomyolipoma and childhood kidney cell carcinoma. An important gene associated with Testicular Infarct is PHYH (Phytanoyl-CoA 2-Hydroxylase), and among its related pathways/superpathways are Folate Metabolism and Wnt / Hedgehog / Notch. Affiliated tissues include testis, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and liver/biliary system

Related Diseases for Testicular Infarct

Diseases related to Testicular Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 74)
id Related Disease Score Top Affiliating Genes
1 angiomyolipoma 29.2 AFP POU5F1 TNFRSF8
2 childhood kidney cell carcinoma 10.3 AFP POU5F1
3 esophagus liposarcoma 10.3 AFP POU5F1
4 klatskin's tumor 10.3 AFP UCHL1
5 atrophic rhinitis 10.3 AFP POU5F1
6 kidney disease 10.3 AFP POU5F1
7 inhibited male orgasm 10.3 AFP POU5F1
8 pneumothorax 10.2 AFP POU5F1
9 uterine corpus myxoid leiomyosarcoma 10.2 PTPRC UCHL1
10 bladder carcinoma in situ 10.2 AFP FUT4
11 cervical polyp 10.2 CRP MTHFR
12 cutaneous porphyria 10.2 KIT UCHL1
13 mood disorder 10.2 AFP KIT
14 persian gulf syndrome 10.2 AFP FUT4
15 lung sarcoma 10.2 AFP FUT4
16 endometrial adenocarcinoma 10.2 HBB MTHFR
17 ovarian germ cell teratoma 10.1 AFP KIT
18 lymphosarcoma 10.1 PHYH PTPRC UCHL1
19 sphenoid sinus squamous cell carcinoma 10.1 AFP KIT
20 houlston ironton temple syndrome 10.1 CRP MTHFR
21 mental retardation, autosomal recessive 33 10.1 CRP MTHFR
22 ovary serous adenocarcinoma 10.1 CRP KIT
23 freemartinism 10.1 KIT PTPRC
24 arcus senilis 10.1 CRP MTHFR
25 rhabdoid cancer 10.1 KIT PTPRC
26 choriocarcinoma of ovary 10.1 KIT PTPRC
27 cranial nerve disease 10.1 AFP KIT
28 anterior optic tract meningioma 10.1 AFP TNFRSF8
29 central nervous system disease 10.1 AFP FUT4 POU5F1
30 endodermal sinus tumor 10.1 KIT PTPRC
31 toxascariasis 10.1 AFP FUT4 POU5F1
32 estrogen-receptor negative breast cancer 10.1 PTPRC UCHL1
33 herpetic whitlow 10.1 TNFRSF8 UCHL1
34 blepharochalasis 10.1 AFP CRP MTHFR
35 dysgammaglobulinemia 10.0 AFP MTHFR
36 arthus reaction 10.0 AFP KIT
37 atopic dermatitis 10.0 AFP KIT POU5F1
38 malignant pleural solitary fibrous tumor 10.0 AFP KIT POU5F1
39 akinetopsia 10.0 FUT4 PTPRC
40 tactile epilepsy 10.0 AFP FUT4
41 neurofibromatosis 10.0 KIT PTPRC
42 penile disease 10.0 PTPRC TNFRSF8
43 rectum leiomyoma 10.0 AFP KIT PTPRC
44 omodysplasia 2 10.0 PTPRC TNFRSF8
45 villous adenoma 10.0 CRP MTHFR
46 geniculate herpes zoster 10.0 AFP CRP PTPRC UCHL1
47 pediatric liposarcoma 10.0 AFP POU5F1 TNFRSF8
48 sensory organ benign neoplasm 10.0 PTPRC TNFRSF8
49 ureter transitional cell carcinoma 10.0 FUT4 TNFRSF8
50 gastrointestinal stromal tumor 10.0 KIT MTHFR UCHL1

Graphical network of the top 20 diseases related to Testicular Infarct:



Diseases related to Testicular Infarct

Symptoms & Phenotypes for Testicular Infarct

GenomeRNAi Phenotypes related to Testicular Infarct according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-109 9.6 PTPRC
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 9.6 PTPRC
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-148 9.6 CRP
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.6 MTHFR
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.6 PTPRC
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.6 MTHFR
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.6 MTHFR CRP
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.6 PTPRC
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.6 MTHFR
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.6 PTPRC CRP MTHFR
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.6 MTHFR
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-86 9.6 MTHFR
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.6 PTPRC
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.6 CRP
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.6 MTHFR
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-95 9.6 MTHFR

MGI Mouse Phenotypes related to Testicular Infarct:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.1 AFP KIT PHYH POU5F1 PTPRC UCHL1

Drugs & Therapeutics for Testicular Infarct

Search Clinical Trials , NIH Clinical Center for Testicular Infarct

Genetic Tests for Testicular Infarct

Anatomical Context for Testicular Infarct

MalaCards organs/tissues related to Testicular Infarct:

39
Testis

Publications for Testicular Infarct

Articles related to Testicular Infarct:

(show all 22)
id Title Authors Year
1
A case of testicular infarction from the complications of Klebsiella oxytoca induced acute epididymitis. ( 26643901 )
2016
2
Acute Epididymo-orchitis-Related Global Testicular Infarction: Clinical and Ultrasound Findings With an Emphasis on the Juxta-epididymal String-of-Bead Sign. ( 27556195 )
2016
3
Testicular infarction and rupture: an uncommon complication of epididymo-orchitis. ( 27165751 )
2016
4
Identify Before Orchiectomy: Segmental Testicular Infarct. ( 25945726 )
2015
5
Testicular infarction after angioembolization of an ipsilateral renal angiomyolipoma. ( 23978372 )
2013
6
Multidrug resistant epididymitis progressing to testicular infarct and orchiectomy. ( 24379982 )
2013
7
Global testicular infarction in the presence of epididymitis: clinical features, appearances on grayscale, color Doppler, and contrast-enhanced sonography, and histologic correlation. ( 23269723 )
2013
8
Significance of reversal of diastolic blood flow in the evolution of testicular infarction as a complication of epididymo-orchitis. ( 22470666 )
2009
9
Idiopathic testicular infarction in a boy initially suspected to have acute epididymo-orchitis associated with mycoplasma infection and Henoch-SchAPnlein purpura. ( 18753011 )
2009
10
Segmental testicular infarction due to cholesterol embolism: not the first case, but the first report. ( 18844943 )
2008
11
Idiopathic testicular infarction initially masquerading as urolithiasis and epididymitis. ( 17606112 )
2007
12
Bilateral testicular infarction and orchiectomy as a complication of polyarteritis nodosa. ( 18231620 )
2007
13
Testicular infarction secondary to protein S deficiency: a case report. ( 16827935 )
2006
14
[Testicular infarction without torsion in cryptorchism]. ( 12765076 )
2003
15
Testicular infarction associated with protein S deficiency. ( 11257684 )
2001
16
Testicular infarction in a patient with epididymitis. ( 9835481 )
1998
17
Special imaging casebook. Neonatal spermatic cord torsion and testicular infarction. ( 7830162 )
1994
18
Oversized "bullseye" with central activity. A scintigraphic appearance of hemorrhagic testicular infarct following traumatic rupture of the testicle. ( 8403724 )
1993
19
Malakoplakia of epididymis associated with testicular infarction. ( 10071557 )
1993
20
Bilateral testicular infarction caused by epididymitis. ( 1872237 )
1991
21
Postsurgical focal testicular infarct. ( 3727192 )
1986
22
Evolution of acute epididymitis to testicular infarction. Scintigraphic demonstration. ( 3006965 )
1986

Variations for Testicular Infarct

Expression for Testicular Infarct

Search GEO for disease gene expression data for Testicular Infarct.

Pathways for Testicular Infarct

Pathways related to Testicular Infarct according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.66 CRP HBB MTHFR
2 11.39 AFP FUT4 POU5F1
3 10.52 KIT PTPRC TNFRSF8

GO Terms for Testicular Infarct

Biological processes related to Testicular Infarct according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 T cell differentiation GO:0030217 8.62 KIT PTPRC

Molecular functions related to Testicular Infarct according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine binding GO:0019955 8.62 KIT POU5F1

Sources for Testicular Infarct

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....