MCID: TST007
MIFTS: 25

Testicular Infarct

Categories: Reproductive diseases

Aliases & Classifications for Testicular Infarct

MalaCards integrated aliases for Testicular Infarct:

Name: Testicular Infarct 12 14
Infarction of Testis 12 69
Testicular Infarction 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5104
NCIt 47 C27617
SNOMED-CT 64 33793000
UMLS 69 C0392041

Summaries for Testicular Infarct

MalaCards based summary : Testicular Infarct, also known as infarction of testis, is related to intracranial hypotension and breast secretory carcinoma. An important gene associated with Testicular Infarct is PHYH (Phytanoyl-CoA 2-Hydroxylase), and among its related pathways/superpathways are Wnt / Hedgehog / Notch and B Cell Development Pathways. Affiliated tissues include testis, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and liver/biliary system

Related Diseases for Testicular Infarct

Diseases related to Testicular Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
id Related Disease Score Top Affiliating Genes
1 intracranial hypotension 10.7 AFP POU5F1
2 breast secretory carcinoma 10.7 AFP UCHL1
3 macular retinal edema 10.7 AFP POU5F1
4 atypical lipomatous tumor 10.7 AFP POU5F1
5 malignant syringoma 10.6 AFP POU5F1
6 pneumothorax 10.6 AFP POU5F1
7 ethmoid sinus schneiderian papilloma 10.5 PTPRC UCHL1
8 intestine carcinoma in situ 10.5 AFP FUT4
9 estrogen-receptor positive breast cancer 10.5 PTPRC UCHL1
10 solitary bone cyst 10.4 PTPRC UCHL1
11 dental abscess 10.4 CRP MTHFR
12 rectosigmoid junction neoplasm 10.4 AFP FUT4
13 malignant peritoneal solitary fibrous tumor 10.4 AFP FUT4
14 frozen shoulder 10.4 CRP UCHL1
15 cutaneous porphyria 10.4 KIT UCHL1
16 glucosephosphate dehydrogenase deficiency 10.4 HBB MTHFR
17 giant adenofibroma of the breast 10.4 AFP KIT
18 arcus senilis 10.4 CRP MTHFR
19 gangliosidosis gm1 10.4 AFP KIT
20 tactile epilepsy 10.3 AFP FUT4
21 avian influenza 10.3 FUT4 PHYH
22 homologous wasting disease 10.3 CRP MTHFR
23 islet cell tumor 10.3 CRP MTHFR
24 sphenoid sinus squamous cell carcinoma 10.3 AFP KIT
25 malignant teratoma 10.3 AFP KIT
26 postcricoid region cancer 10.3 PHYH PTPRC UCHL1
27 spermatogenic failure 14 10.3 CRP MTHFR
28 urethral villous adenoma 10.3 AFP KIT
29 small intestinal vasoactive intestinal peptide producing tumor 10.3 CRP KIT
30 dysgammaglobulinemia 10.3 AFP MTHFR
31 hypersensitivity reaction type iii disease 10.3 AFP KIT
32 delta chain disease 10.3 FUT4 PTPRC
33 capillary hemangioma 10.2 AFP MTHFR
34 filamentary keratitis 10.2 KIT PTPRC
35 hepatocellular adenoma 10.2 CRP MTHFR
36 pericoronitis 10.2 KIT PTPRC
37 fallopian tube squamous cell carcinoma 10.2 KIT PTPRC
38 nasal cavity squamous cell carcinoma 10.2 AFP KIT
39 sleep disorder 10.2 AFP POU5F1
40 malignant histiocytosis 10.2 TNFRSF8 UCHL1
41 aryepiglottic fold cancer 10.2 AFP MTHFR
42 myositis 10.2 AFP TNFRSF8
43 neurodermatitis 10.2 AFP FUT4 POU5F1
44 thoracic outlet syndrome 10.1 AFP FUT4 POU5F1
45 breast disease 10.1 AFP CRP MTHFR
46 cholesteatoma 10.1 KIT PTPRC
47 lung clear cell-sugar-tumor 10.0 KIT UCHL1
48 central nervous system disease 10.0 AFP KIT POU5F1
49 brown-vialetto-van laere syndrome 10.0 AFP KIT POU5F1
50 penile disease 10.0 PTPRC TNFRSF8

Graphical network of the top 20 diseases related to Testicular Infarct:



Diseases related to Testicular Infarct

Symptoms & Phenotypes for Testicular Infarct

GenomeRNAi Phenotypes related to Testicular Infarct according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-109 9.6 PTPRC
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 9.6 PTPRC
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-148 9.6 CRP
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.6 MTHFR
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.6 PTPRC
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.6 MTHFR
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.6 CRP MTHFR
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.6 PTPRC
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.6 MTHFR
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.6 PTPRC CRP MTHFR
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.6 MTHFR
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-86 9.6 MTHFR
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.6 PTPRC
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.6 CRP
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.6 MTHFR
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-95 9.6 MTHFR

MGI Mouse Phenotypes related to Testicular Infarct:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.1 AFP KIT PHYH POU5F1 PTPRC UCHL1

Drugs & Therapeutics for Testicular Infarct

Search Clinical Trials , NIH Clinical Center for Testicular Infarct

Genetic Tests for Testicular Infarct

Anatomical Context for Testicular Infarct

MalaCards organs/tissues related to Testicular Infarct:

39
Testis

Publications for Testicular Infarct

Articles related to Testicular Infarct:

(show all 22)
id Title Authors Year
1
Testicular infarction and rupture: an uncommon complication of epididymo-orchitis. ( 27165751 )
2016
2
A case of testicular infarction from the complications of Klebsiella oxytoca induced acute epididymitis. ( 26643901 )
2016
3
Acute Epididymo-orchitis-Related Global Testicular Infarction: Clinical and Ultrasound Findings With an Emphasis on the Juxta-epididymal String-of-Bead Sign. ( 27556195 )
2016
4
Identify Before Orchiectomy: Segmental Testicular Infarct. ( 25945726 )
2015
5
Multidrug resistant epididymitis progressing to testicular infarct and orchiectomy. ( 24379982 )
2013
6
Testicular infarction after angioembolization of an ipsilateral renal angiomyolipoma. ( 23978372 )
2013
7
Global testicular infarction in the presence of epididymitis: clinical features, appearances on grayscale, color Doppler, and contrast-enhanced sonography, and histologic correlation. ( 23269723 )
2013
8
Significance of reversal of diastolic blood flow in the evolution of testicular infarction as a complication of epididymo-orchitis. ( 22470666 )
2009
9
Idiopathic testicular infarction in a boy initially suspected to have acute epididymo-orchitis associated with mycoplasma infection and Henoch-SchAPnlein purpura. ( 18753011 )
2009
10
Segmental testicular infarction due to cholesterol embolism: not the first case, but the first report. ( 18844943 )
2008
11
Idiopathic testicular infarction initially masquerading as urolithiasis and epididymitis. ( 17606112 )
2007
12
Bilateral testicular infarction and orchiectomy as a complication of polyarteritis nodosa. ( 18231620 )
2007
13
Testicular infarction secondary to protein S deficiency: a case report. ( 16827935 )
2006
14
[Testicular infarction without torsion in cryptorchism]. ( 12765076 )
2003
15
Testicular infarction associated with protein S deficiency. ( 11257684 )
2001
16
Testicular infarction in a patient with epididymitis. ( 9835481 )
1998
17
Special imaging casebook. Neonatal spermatic cord torsion and testicular infarction. ( 7830162 )
1994
18
Oversized "bullseye" with central activity. A scintigraphic appearance of hemorrhagic testicular infarct following traumatic rupture of the testicle. ( 8403724 )
1993
19
Malakoplakia of epididymis associated with testicular infarction. ( 10071557 )
1993
20
Bilateral testicular infarction caused by epididymitis. ( 1872237 )
1991
21
Evolution of acute epididymitis to testicular infarction. Scintigraphic demonstration. ( 3006965 )
1986
22
Postsurgical focal testicular infarct. ( 3727192 )
1986

Variations for Testicular Infarct

Expression for Testicular Infarct

Search GEO for disease gene expression data for Testicular Infarct.

Pathways for Testicular Infarct

Pathways related to Testicular Infarct according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.39 AFP FUT4 POU5F1
2 10.52 KIT PTPRC TNFRSF8

GO Terms for Testicular Infarct

Biological processes related to Testicular Infarct according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 T cell differentiation GO:0030217 8.62 KIT PTPRC

Molecular functions related to Testicular Infarct according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine binding GO:0019955 8.62 KIT POU5F1

Sources for Testicular Infarct

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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