MCID: TST007
MIFTS: 28

Testicular Infarct malady

Category: Reproductive diseases

Aliases & Classifications for Testicular Infarct

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Aliases & Descriptions for Testicular Infarct:

Name: Testicular Infarct 11 13
Infarction of Testis 11 66
 
Testicular Infarction 11

Classifications:



External Ids:

Disease Ontology11 DOID:5104
SNOMED-CT60 33793000
NCIt43 C27617

Summaries for Testicular Infarct

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MalaCards based summary: Testicular Infarct, also known as infarction of testis, is related to subglottic angioma and eccrine adenocarcinoma, and has symptoms including pain in testicle, epididymal tenderness and spermatic cord pain. An important gene associated with Testicular Infarct is PHYH (Phytanoyl-CoA 2-Hydroxylase), and among its related pathways are Folate Metabolism and Wnt / Hedgehog / Notch. Affiliated tissues include testis, and related mouse phenotype liver/biliary system.

Related Diseases for Testicular Infarct

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Diseases related to Testicular Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 98)
idRelated DiseaseScoreTop Affiliating Genes
1subglottic angioma10.6AFP, POU5F1
2eccrine adenocarcinoma10.6AFP, UCHL1
3cervical alveolar soft part sarcoma10.6AFP, POU5F1
4hereditary breast ovarian cancer10.6AFP, POU5F1
5adult teratoma10.6AFP, POU5F1
6mediastinum teratoma10.6AFP, POU5F1
7ovarian clear cell malignant adenofibroma10.5PTPRC, UCHL1
8polyneuropathy due to drug10.5CRP, UCHL1
9esophageal leukoplakia10.4AFP, FUT4
10sezary's disease10.4PTPRC, UCHL1
11coloboma-obesity-hypogenitalism-mental retardation syndrome10.4AFP, MTHFR
12dental abscess10.4CRP, MTHFR
13contact dermatitis10.4AFP, FUT4
14malignant epithelial mesothelioma10.4AFP, FUT4
15persian gulf syndrome10.4FUT4, PHYH
16solitary bone cyst10.4PTPRC, UCHL1
17congenital nonspherocytic hemolytic anemia10.4HBB, MTHFR
18homocystinuria due to defect in methylation cbl g10.4CRP, MTHFR
19reflex epilepsy10.4AFP, FUT4
20thbd-related atypical hemolytic-uremic syndrome10.3HBB, MTHFR
21islet cell tumor10.3CRP, MTHFR
22hepatocellular adenoma10.3CRP, MTHFR
23gangliosidosis gm210.3AFP, KIT
24pneumocystosis10.3CRP, MTHFR
25sphenoidal sinus cancer10.3AFP, KIT
26localized pulmonary fibrosis10.3AFP, KIT
27vein disease10.3PHYH, PTPRC, UCHL1
28peripheral nervous system disease10.3CRP, KIT
29mental retardation, autosomal recessive 3310.3CRP, MTHFR
30vibratory urticaria10.3AFP, KIT
31nephrogenic adenofibroma10.2AFP, KIT
32multiple chemical sensitivity10.2KIT, PTPRC
33olfactory nerve disease10.2KIT, PTPRC
34delta chain disease10.2FUT4, PTPRC
35ureter squamous cell carcinoma10.2KIT, PTPRC
36dermatitis10.2AFP, MTHFR
37nonsyndromic congenital nail disorder 210.2KIT, UCHL1
38pulmonary coin lesion10.2KIT, UCHL1
39breast squamous cell carcinoma10.2AFP, KIT
40tonsillar pillar cancer10.2KIT, PTPRC
41vulvar sebaceous carcinoma10.2KIT, UCHL1
42tibial adamantinoma10.2AFP, TNFRSF8
43lip carcinoma in situ10.2AFP, MTHFR
44psychosexual disorder10.2CRP, MTHFR
45soft palate cancer10.2TNFRSF8, UCHL1
46embryonal carcinoma10.1AFP, FUT4, POU5F1
47small cell sarcoma10.1AFP, FUT4, POU5F1
48cervix erosion10.1AFP, CRP, MTHFR
49spastic paraplegia 3a10.1HBB, MTHFR
50neurodermatitis10.0AFP, KIT, POU5F1

Graphical network of the top 20 diseases related to Testicular Infarct:



Diseases related to testicular infarct

Symptoms for Testicular Infarct

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UMLS symptoms related to Testicular Infarct:


pain in testicle, epididymal tenderness, spermatic cord pain

Drugs & Therapeutics for Testicular Infarct

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Testicular Infarct

Genetic Tests for Testicular Infarct

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Anatomical Context for Testicular Infarct

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MalaCards organs/tissues related to Testicular Infarct:

34
Testis

Animal Models for Testicular Infarct or affiliated genes

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MGI Mouse Phenotypes related to Testicular Infarct:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.6AFP, KIT, PHYH, POU5F1, PTPRC, UCHL1

Publications for Testicular Infarct

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Articles related to Testicular Infarct:

(show all 21)
idTitleAuthorsYear
1
Testicular infarction and rupture: an uncommon complication of epididymo-orchitis. (27165751)
2016
2
Acute Epididymo-orchitis-Related Global Testicular Infarction: Clinical and Ultrasound Findings With an Emphasis on the Juxta-epididymal String-of-Bead Sign. (27556195)
2016
3
Identify Before Orchiectomy: Segmental Testicular Infarct. (25945726)
2015
4
Testicular infarction after angioembolization of an ipsilateral renal angiomyolipoma. (23978372)
2013
5
Multidrug resistant epididymitis progressing to testicular infarct and orchiectomy. (24379982)
2013
6
Global testicular infarction in the presence of epididymitis: clinical features, appearances on grayscale, color Doppler, and contrast-enhanced sonography, and histologic correlation. (23269723)
2013
7
Significance of reversal of diastolic blood flow in the evolution of testicular infarction as a complication of epididymo-orchitis. (22470666)
2009
8
Idiopathic testicular infarction in a boy initially suspected to have acute epididymo-orchitis associated with mycoplasma infection and Henoch-SchAPnlein purpura. (18753011)
2009
9
Segmental testicular infarction due to cholesterol embolism: not the first case, but the first report. (18844943)
2008
10
Bilateral testicular infarction and orchiectomy as a complication of polyarteritis nodosa. (18231620)
2007
11
Idiopathic testicular infarction initially masquerading as urolithiasis and epididymitis. (17606112)
2007
12
Testicular infarction secondary to protein S deficiency: a case report. (16827935)
2006
13
Testicular infarction without torsion in cryptorchism]. (12765076)
2003
14
Testicular infarction associated with protein S deficiency. (11257684)
2001
15
Testicular infarction in a patient with epididymitis. (9835481)
1998
16
Special imaging casebook. Neonatal spermatic cord torsion and testicular infarction. (7830162)
1994
17
Oversized "bullseye" with central activity. A scintigraphic appearance of hemorrhagic testicular infarct following traumatic rupture of the testicle. (8403724)
1993
18
Malakoplakia of epididymis associated with testicular infarction. (10071557)
1993
19
Bilateral testicular infarction caused by epididymitis. (1872237)
1991
20
Postsurgical focal testicular infarct. (3727192)
1986
21
Evolution of acute epididymitis to testicular infarction. Scintigraphic demonstration. (3006965)
1986

Variations for Testicular Infarct

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Expression for genes affiliated with Testicular Infarct

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Search GEO for disease gene expression data for Testicular Infarct.

Pathways for genes affiliated with Testicular Infarct

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Pathways related to Testicular Infarct according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5HBB, MTHFR
29.3AFP, FUT4, POU5F1
3
Show member pathways
9.2CRP, HBB, MTHFR
48.6KIT, PTPRC, TNFRSF8

GO Terms for genes affiliated with Testicular Infarct

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Biological processes related to Testicular Infarct according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell differentiationGO:00302179.4KIT, PTPRC

Sources for Testicular Infarct

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet