MCID: TST007
MIFTS: 26

Testicular Infarct malady

Category: Reproductive diseases

Aliases & Classifications for Testicular Infarct

About this section

Aliases & Descriptions for Testicular Infarct:

Name: Testicular Infarct 11 13
Infarction of Testis 11 68
 
Testicular Infarction 11

Classifications:



External Ids:

Disease Ontology11 DOID:5104
SNOMED-CT62 33793000
NCIt45 C27617

Summaries for Testicular Infarct

About this section
MalaCards based summary: Testicular Infarct, also known as infarction of testis, is related to angiomyolipoma and childhood kidney cell carcinoma. An important gene associated with Testicular Infarct is PHYH (Phytanoyl-CoA 2-Hydroxylase), and among its related pathways are Wnt / Hedgehog / Notch and Folate Metabolism. Affiliated tissues include testis, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and liver/biliary system.

Related Diseases for Testicular Infarct

About this section

Diseases related to Testicular Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 74)
idRelated DiseaseScoreTop Affiliating Genes
1angiomyolipoma29.2AFP, POU5F1, TNFRSF8
2childhood kidney cell carcinoma10.3AFP, POU5F1
3esophagus liposarcoma10.3AFP, POU5F1
4klatskin's tumor10.3AFP, UCHL1
5atrophic rhinitis10.3AFP, POU5F1
6kidney disease10.3AFP, POU5F1
7inhibited male orgasm10.3AFP, POU5F1
8pneumothorax10.2AFP, POU5F1
9uterine corpus myxoid leiomyosarcoma10.2PTPRC, UCHL1
10bladder carcinoma in situ10.2AFP, FUT4
11cervical polyp10.2CRP, MTHFR
12cutaneous porphyria10.2KIT, UCHL1
13mood disorder10.2AFP, KIT
14persian gulf syndrome10.2AFP, FUT4
15lung sarcoma10.2AFP, FUT4
16endometrial adenocarcinoma10.2HBB, MTHFR
17ovarian germ cell teratoma10.1AFP, KIT
18lymphosarcoma10.1PHYH, PTPRC, UCHL1
19sphenoid sinus squamous cell carcinoma10.1AFP, KIT
20houlston ironton temple syndrome10.1CRP, MTHFR
21mental retardation, autosomal recessive 3310.1CRP, MTHFR
22ovary serous adenocarcinoma10.1CRP, KIT
23freemartinism10.1KIT, PTPRC
24arcus senilis10.1CRP, MTHFR
25rhabdoid cancer10.1KIT, PTPRC
26choriocarcinoma of ovary10.1KIT, PTPRC
27cranial nerve disease10.1AFP, KIT
28anterior optic tract meningioma10.1AFP, TNFRSF8
29central nervous system disease10.1AFP, FUT4, POU5F1
30endodermal sinus tumor10.1KIT, PTPRC
31toxascariasis10.1AFP, FUT4, POU5F1
32estrogen-receptor negative breast cancer10.1PTPRC, UCHL1
33herpetic whitlow10.1TNFRSF8, UCHL1
34blepharochalasis10.1AFP, CRP, MTHFR
35dysgammaglobulinemia10.0AFP, MTHFR
36arthus reaction10.0AFP, KIT
37atopic dermatitis10.0AFP, KIT, POU5F1
38malignant pleural solitary fibrous tumor10.0AFP, KIT, POU5F1
39akinetopsia10.0FUT4, PTPRC
40tactile epilepsy10.0AFP, FUT4
41neurofibromatosis10.0KIT, PTPRC
42penile disease10.0PTPRC, TNFRSF8
43rectum leiomyoma10.0AFP, KIT, PTPRC
44omodysplasia 210.0PTPRC, TNFRSF8
45villous adenoma10.0CRP, MTHFR
46geniculate herpes zoster10.0AFP, CRP, PTPRC, UCHL1
47pediatric liposarcoma10.0AFP, POU5F1, TNFRSF8
48sensory organ benign neoplasm10.0PTPRC, TNFRSF8
49ureter transitional cell carcinoma10.0FUT4, TNFRSF8
50gastrointestinal stromal tumor10.0KIT, MTHFR, UCHL1

Graphical network of the top 20 diseases related to Testicular Infarct:



Diseases related to testicular infarct

Symptoms & Phenotypes for Testicular Infarct

About this section

GenomeRNAi Phenotypes related to Testicular Infarct according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-849.8CRP, MTHFR, PTPRC

MGI Mouse Phenotypes related to Testicular Infarct according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.1AFP, KIT, PHYH, POU5F1, PTPRC, UCHL1

Drugs & Therapeutics for Testicular Infarct

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Testicular Infarct

Genetic Tests for Testicular Infarct

About this section

Anatomical Context for Testicular Infarct

About this section

MalaCards organs/tissues related to Testicular Infarct:

36
Testis

Publications for Testicular Infarct

About this section

Articles related to Testicular Infarct:

(show all 22)
idTitleAuthorsYear
1
A case of testicular infarction from the complications of Klebsiella oxytoca induced acute epididymitis. (26643901)
2016
2
Acute Epididymo-orchitis-Related Global Testicular Infarction: Clinical and Ultrasound Findings With an Emphasis on the Juxta-epididymal String-of-Bead Sign. (27556195)
2016
3
Testicular infarction and rupture: an uncommon complication of epididymo-orchitis. (27165751)
2016
4
Identify Before Orchiectomy: Segmental Testicular Infarct. (25945726)
2015
5
Testicular infarction after angioembolization of an ipsilateral renal angiomyolipoma. (23978372)
2013
6
Multidrug resistant epididymitis progressing to testicular infarct and orchiectomy. (24379982)
2013
7
Global testicular infarction in the presence of epididymitis: clinical features, appearances on grayscale, color Doppler, and contrast-enhanced sonography, and histologic correlation. (23269723)
2013
8
Significance of reversal of diastolic blood flow in the evolution of testicular infarction as a complication of epididymo-orchitis. (22470666)
2009
9
Idiopathic testicular infarction in a boy initially suspected to have acute epididymo-orchitis associated with mycoplasma infection and Henoch-SchAPnlein purpura. (18753011)
2009
10
Segmental testicular infarction due to cholesterol embolism: not the first case, but the first report. (18844943)
2008
11
Idiopathic testicular infarction initially masquerading as urolithiasis and epididymitis. (17606112)
2007
12
Bilateral testicular infarction and orchiectomy as a complication of polyarteritis nodosa. (18231620)
2007
13
Testicular infarction secondary to protein S deficiency: a case report. (16827935)
2006
14
Testicular infarction without torsion in cryptorchism]. (12765076)
2003
15
Testicular infarction associated with protein S deficiency. (11257684)
2001
16
Testicular infarction in a patient with epididymitis. (9835481)
1998
17
Special imaging casebook. Neonatal spermatic cord torsion and testicular infarction. (7830162)
1994
18
Oversized "bullseye" with central activity. A scintigraphic appearance of hemorrhagic testicular infarct following traumatic rupture of the testicle. (8403724)
1993
19
Malakoplakia of epididymis associated with testicular infarction. (10071557)
1993
20
Bilateral testicular infarction caused by epididymitis. (1872237)
1991
21
Postsurgical focal testicular infarct. (3727192)
1986
22
Evolution of acute epididymitis to testicular infarction. Scintigraphic demonstration. (3006965)
1986

Variations for Testicular Infarct

About this section

Expression for genes affiliated with Testicular Infarct

About this section
Search GEO for disease gene expression data for Testicular Infarct.

Pathways for genes affiliated with Testicular Infarct

About this section

Pathways related to Testicular Infarct according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3AFP, FUT4, POU5F1
2
Show member pathways
9.2CRP, HBB, MTHFR
38.6KIT, PTPRC, TNFRSF8

GO Terms for genes affiliated with Testicular Infarct

About this section

Biological processes related to Testicular Infarct according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell differentiationGO:00302179.4KIT, PTPRC

Molecular functions related to Testicular Infarct according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine bindingGO:00199559.5KIT, POU5F1

Sources for Testicular Infarct

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet