MCID: TST003
MIFTS: 21

Testicular Leukemia malady

Reproductive diseases category

Summaries for Testicular Leukemia

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32MalaCards
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MalaCards: Testicular Leukemia is related to leukemia and acute leukemia. An important gene associated with Testicular Leukemia is CCR10 (chemokine (C-C motif) receptor 10). Affiliated tissues include myeloid, monocytes and bone.

Aliases & Classifications for Testicular Leukemia

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 39NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


Aliases & Descriptions:

testicular leukemia 8 10 60


External Ids:

Disease Ontology8 DOID:12286
NCIt39 C9277

Related Diseases for Testicular Leukemia

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17GeneCards, 18GeneDecks
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Diseases related to Testicular Leukemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1leukemia30.9PREB
2acute leukemia10.2
3acute monocytic leukemia10.0
4acute lymphocytic leukemia10.0
5childhood leukemia10.0
6lymphoblastic leukemia10.0
7monocytic leukemia10.0
8testicular disease10.0

Graphical network of diseases related to Testicular Leukemia:



Diseases related to testicular leukemia

Clinical Features for Testicular Leukemia

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Drugs & Therapeutics for Testicular Leukemia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Testicular Leukemia

Drug clinical trials:

Search ClinicalTrials for Testicular Leukemia

Search NIH Clinical Center for Testicular Leukemia

Search CenterWatch for Testicular Leukemia

Genetic Tests for Testicular Leukemia

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Anatomical Context for Testicular Leukemia

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Sources:
32MalaCards
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MalaCards organs/tissues related to Testicular Leukemia:

32
Myeloid, Monocytes, Bone, Bone marrow, T cells

Animal Models for Testicular Leukemia or affiliated genes

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Publications for Testicular Leukemia

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50PubMed
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Articles related to Testicular Leukemia:

(show all 42)
idTitleAuthorsYear
1
Testicular Myeloid Sarcoma: An Unusual Presentation of Infant Acute Myeloid Leukemia. (24390442)
2014
2
Paraneoplastic autoimmunity associated with testicular myeloid sarcoma and chronic myelomonocytic leukemia. (24198985)
2013
3
Primary plasma cell leukemia followed by testicular plasmacytoma. (21229400)
2011
4
Overt testicular disease at diagnosis in childhood acute lymphoblastic leukemia: prognostic significance and role of testicular irradiation. (20589462)
2010
5
Testicular cancer developed in a chronic myeloid leukemia patient with a continued complete cytogenetic and molecular response to imatinib. A case report and review of the literature. (20359744)
2010
6
Relapsed testicular leukemia: local insights in to a vanishing disease. (20448368)
2010
7
Possible alternative strategy for stage I imatinib-sensitive testicular seminoma; lessons from a case associated with Philadelphia chromosome-positive acute lymphoblastic leukemia. (20080832)
2010
8
Adult T cell leukemia-lymphoma with testicular involvement. (18941745)
2009
9
Risk of leukemia among survivors of testicular cancer: a population-based study of 42,722 patients. (18433667)
2008
10
Decontamination of leukemic cells and enrichment of germ cells from testicular samples from rats with Roser's T-cell leukemia by flow cytometric sorting. (18042634)
2007
11
Overt testicular disease (OTD) at diagnosis is not associated with a poor prognosis in childhood acute lymphoblastic leukemia: results of the EORTC CLG Study 58881. (16358303)
2007
12
Isolated testicular and bone relapse in children with acute myeloblastic leukemia and chronic graft versus host disease after allogeneic BMT. (17907524)
2007
13
Overt testicular disease at diagnosis of childhood acute lymphoblastic leukemia: lack of therapeutic role of local irradiation. (15973454)
2005
14
Unilateral testicular mass in man with chronic myelomonocytic leukemia: unusual presentation of chronic myelomonocytic leukemia sequela. (15882745)
2005
15
Testicular leukemia inhibitory factor (LIF) and LIF receptor mediate phosphorylation of signal transducers and activators of transcription (STAT)-3 and STAT-1 and induce c-fos transcription and activator protein-1 activation in rat Sertoli but not germ cells. (9528974)
1998
16
Testicular leukemia relapse. Fine needle aspiration findings. (9568129)
1998
17
Multiple myeloma: a patient with unusual features including intracranial and meningeal involvement, testicular involvement, organomegaly, and plasma cell leukemia. (9423817)
1998
18
Secondary acute monocytic leukemia occurring during the treatment of a testicular germ cell tumor. A case report and review of the literature. (9253126)
1997
19
Ultrasound diagnosis and follow-up of testicular monocytic leukemia. (9321719)
1997
20
Overt testicular disease at diagnosis is associated with high risk features and a poor prognosis in patients with childhood acute lymphoblastic leukemia. (8941016)
1996
21
Testicular relapse, with Ph-positive chromosome after bone marrow transplantation for acute lymphocytic leukemia]. (8450610)
1993
22
Needle biopsy in the diagnosis of testicular leukemia in children. (2709505)
1989
23
Testicular relapse in adult acute lymphocytic leukemia: a case report and literature review. (2649778)
1989
24
Testicular enlargement as a presenting feature of monocytic leukemia in an infant. (2593063)
1989
25
Immunophenotyping to detect and characterize acute lymphocytic leukemia in testicular biopsies. (2787504)
1989
26
Occult testicular leukemia in a patient with acute monocytic leukemia. (3152942)
1987
27
The enigma of testicular leukemia: a critical review. (3537653)
1986
28
Testicular disease in Singapore children with acute leukemia. (6595957)
1984
29
Incidence and detection of testicular leukemia in children. (6590152)
1984
30
Treatment of murine testicular leukemia. (6722788)
1984
31
Management of children with isolated testicular leukemia. (6498764)
1984
32
The ultrasound diagnosis of testicular leukemia. (6400260)
1983
33
Ultrasound diagnosis of testicular leukemia. (6571758)
1983
34
Isolated testicular leukemia following bone marrow transplant for acute lymphocytic leukemia. The need for pretransplant testicular biopsies. (7046495)
1982
35
Diagnosis of testicular leukemia. (7201513)
1982
36
Occult testicular leukemia: testicular biopsy at three years continuous complete remission of childhood leukemia: a Southwest Oncology Group Study. (6939470)
1981
37
Proceedings of the tumor board of the Children's Hospital of Philadelphia. Testicular leukemia: incidence and management results. (6946280)
1981
38
Radiotherapy (2500 rad) for testicular leukemia: local control and subsequent clinical events: a Southwest Oncology Group study. (6994868)
1980
39
Clinical and occult testicular leukemia in long-term survivors of acute lymphoblastic leukemia. (6928464)
1980
40
Testicular involvement in plasma-cell leukemia. (4830641)
1974
41
Testicular leukemia. (5413403)
1970
42
Testicular leukemia. (5461011)
1970

Genetic Variations for Testicular Leukemia

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Expression for genes affiliated with Testicular Leukemia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Testicular Leukemia

Search GEO for disease gene expression data for Testicular Leukemia.

Pathways for genes affiliated with Testicular Leukemia

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Compounds for genes affiliated with Testicular Leukemia

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GO Terms for genes affiliated with Testicular Leukemia

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Products for genes affiliated with Testicular Leukemia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Testicular Leukemia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet