MCID: TST004
MIFTS: 33

Testicular Lymphoma malady

Immune diseases, Reproductive diseases categories

Summaries for Testicular Lymphoma

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Testicular Lymphoma, also known as malignant lymphoma of testis, is related to anaplastic large cell lymphoma and central nervous system lymphoma. An important gene associated with Testicular Lymphoma is PTPRC (protein tyrosine phosphatase, receptor type, C), and among its related pathways are Immune response Fc epsilon RI pathway and Lymphocyte Signaling. The compounds cycloheximide and 12-o-tetradecanoylphorbol 13-acetate have been mentioned in the context of this disorder. Affiliated tissues include testis, b cells and bone.

Aliases & Classifications for Testicular Lymphoma

About this section
Sources:
8Disease Ontology, 10DISEASES, 30LifeMap Discovery™, 60UMLS, 39NCIt, 56SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases, Reproductive diseases


Aliases & Descriptions:

testicular lymphoma 8 10 30
malignant lymphoma of testis 8 60
lymphoma of the testis 8


External Ids:

Disease Ontology8 DOID:12253
SNOMED-CT56 277664004
NCIt39 C6810

Related Diseases for Testicular Lymphoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Testicular Lymphoma:



Diseases related to testicular lymphoma

Clinical Features for Testicular Lymphoma

About this section

Drugs & Therapeutics for Testicular Lymphoma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 30LifeMap Discovery™
See all sources

Approved drugs:

Search CenterWatch for Testicular Lymphoma

Drug clinical trials:

Search ClinicalTrials for Testicular Lymphoma

Search NIH Clinical Center for Testicular Lymphoma

Search CenterWatch for Testicular Lymphoma

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Testicular Lymphoma cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Testicular Lymphoma:
Hematopoietic stem cells for treatment of hematologic malignancies
Embryonic/Adult Cultured Cells Related to Testicular Lymphoma:
Bone marrow-derived hematopoietic stem cells

Genetic Tests for Testicular Lymphoma

About this section

Anatomical Context for Testicular Lymphoma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Testicular Lymphoma:

32
Testis, B cells, Bone, T cells, Brain, Prostate, B lymphoblasts, Bone marrow

Animal Models for Testicular Lymphoma or affiliated genes

About this section

Publications for Testicular Lymphoma

About this section
Sources:
50PubMed
See all sources

Articles related to Testicular Lymphoma:

(show top 50)    (show all 108)
idTitleAuthorsYear
1
Cutaneous diffuse large B-cell lymphoma, leg type, secondary to testicular diffuse large B-cell lymphoma. (24354909)
2013
2
F18 FDG positron emission tomography revelation of primary testicular lymphoma with concurrent multiple extra nodal involvement. (24019676)
2013
3
Isolated primary testicular B lymphoblastic lymphoma: an unusual presentation. (23042023)
2013
4
The impact of systemic chemotherapy on testicular FDG activity in young men with Hodgkin's lymphoma. (23389428)
2013
5
Diffuse large B-cell lymphoma in immunoprivileged sites: association of vitreoretinal, testicular and central nervous system lymphoma. (23819861)
2013
6
Testicular lymphoma. (23945480)
2013
7
High prevalence of oncogenic MYD88 and CD79B mutations in primary testicular diffuse large B-cell lymphoma. (24253023)
2013
8
Primary testicular lymphoma with rupture: An unusual presentation. (23633871)
2013
9
Primary testicular lymphoma: experience with 13 cases and literature review. (23355262)
2013
10
Phenotype profiling of primary testicular diffuse large B-cell lymphomas. (23949965)
2013
11
Primary cutaneous diffuse large B-cell lymphoma, leg type and secondary cutaneous involvement by testicular B-cell lymphoma share identical clinicopathological and immunophenotypical features. (21816504)
2012
12
Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature. (22807960)
2012
13
Primary testicular lymphoma with cardiac involvement in an immunocompetent patient: case report and a concise review of literature. (23087799)
2012
14
Impact of chemotherapeutics and advanced testicular cancer or Hodgkin lymphoma on sperm deoxyribonucleic acid integrity. (19591994)
2010
15
Testicular lymphoma, intraocular (vitreoretinal) lymphoma, and brain lymphoma: involvement of three immunoprivileged sites in one patient. (20658596)
2010
16
Primary testicular lymphoma: the site matters. (20497004)
2010
17
Primary testicular lymphoma with extranodal involvement. (19736380)
2009
18
Primary testicular lymphoma involving the spermatic cord and gonadal vein. (19300051)
2009
19
Testicular lymphoma: an update for clinicians. (18854677)
2008
20
Primary testicular lymphoma. (17962036)
2008
21
Sperm aneuploidy frequencies analysed before and after chemotherapy in testicular cancer and Hodgkin's lymphoma patients. (18083744)
2008
22
Testicular relapse of primary central nervous system lymphoma. (17487747)
2007
23
Primary testicular non-Hodgkin's lymphoma with atrial mass as an initial presentation of acquired immunodeficiency syndrome. (17676218)
2007
24
Multiple cranial nerve palsies in testicular lymphoma: report of a case. (17622916)
2007
25
Primary testicular precursor B-lymphoblastic lymphoma: a rare entity. (17852709)
2007
26
Testicular lymphoma: a case report. (18159836)
2007
27
Primary testicular lymphoma. (17945289)
2007
28
The relationship between HLA class II polymorphisms and somatic deletions in testicular B cell lymphomas of Dutch patients. (16720210)
2006
29
Diagnosis of a primary testicular lymphoma by echography and magnetic resonance imaging. (16790401)
2006
30
Primary testicular diffuse large B-cell lymphomas have activated B-cell-like subtype characteristics. (16823896)
2006
31
Imaging diagnosis of testicular lymphoma. (16465583)
2006
32
Array comparative genomic hybridization reveals a very high frequency of deletions of the long arm of chromosome 6 in testicular lymphoma. (16865685)
2006
33
Primary testicular lymphoma--A case report. (16910327)
2006
34
Testicular ischemia due to intravascular large B-cell lymphoma: a novel presentation in an immunosuppressed individual. (14615832)
2003
35
Testicular natural killer/t-cell lymphoma, nasal type, of true natural killer-cell origin. (12456216)
2002
36
Testicular lymphoma: a literature review and report of a case with a zoster-like cutaneous recurrence. (11970763)
2002
37
Deletion 5p11 accompanied by multiple numerical changes in testicular lymphoma. (11734324)
2001
38
Bilateral testicular lymphoma treated with chemotherapy and radiation without orchiectomy: complete response relapsed at 52 months in the vitreous humor. (11248646)
2001
39
A case of bilateral testicular lymphoma. (10393369)
1999
40
Testicular lymphoma. (10375083)
1999
41
Lymphomas with testicular localisation show a consistent BCL-2 expression without a translocation (14;18): a molecular and immunohistochemical study. (7819053)
1995
42
Urinary retention due to prostatic involvement in testicular lymphoma: a case report. (8256685)
1993
43
Testicular lymphoma--the need for a new approach. (1763988)
1991
44
Testicular lymphoma with pancreatitis. (2041014)
1991
45
Sonographic appearance of primary testicular lymphoma. (1950870)
1991
46
Primary testicular lymphoma with central nervous system involvement. (1870344)
1991
47
Testicular lymphoma. A retrospective review of 17 cases. (6689088)
1983
48
Testicular lymphoma: a clinicopathologic study of 22 cases. (548480)
1979
49
Testicular lymphoma: a clinicopathologic study of 22 cases. (581582)
1978
50
Testicular lymphoma. (1090055)
1975

Genetic Variations for Testicular Lymphoma

About this section

Expression for genes affiliated with Testicular Lymphoma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Testicular Lymphoma

Search GEO for disease gene expression data for Testicular Lymphoma.

Pathways for genes affiliated with Testicular Lymphoma

About this section
Sources:
12EMD Millipore, 4Cell Signaling Technology, 37NCBI BioSystems Database
See all sources

Pathways related to Testicular Lymphoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1BCL6, PTPRC
29.1BCL6, PTPRC
39.1BCL6, PTPRC

Compounds for genes affiliated with Testicular Lymphoma

About this section
Sources:
44Novoseek
See all sources

Compounds related to Testicular Lymphoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cycloheximide449.1BCL6, PTPRC
212-o-tetradecanoylphorbol 13-acetate449.0BCL6, PTPRC
3paraffin448.8BCL6, PTPRC

GO Terms for genes affiliated with Testicular Lymphoma

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Testicular Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of B cell proliferationGO:0308909.1BCL6, PTPRC

Products for genes affiliated with Testicular Lymphoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Testicular Lymphoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet