MCID: TST025
MIFTS: 29

Testicular Microlithiasis malady

Reproductive category

Summaries for Testicular Microlithiasis

Sources:
64Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:64 Testicular microlithiasis is an unusual condition diagnosed on testicular ultrasound. It is found in... more...

MalaCards: Testicular Microlithiasis is related to testicular cancer and extragonadal germ cell tumor. An important gene associated with Testicular Microlithiasis is SLC34A2 (solute carrier family 34 (type II sodium/phosphate contransporter), member 2). The compounds oestriol and clomiphene citrate have been mentioned in the context of this disorder. Affiliated tissues include spleen, adrenal gland and testis.

Description from OMIM:47 610441

Aliases & Classifications for Testicular Microlithiasis

Sources:
47OMIM, 61UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive


Aliases & Descriptions:

testicular microlithiasis 47 61


Related Diseases for Testicular Microlithiasis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Testicular Microlithiasis:



Diseases related to testicular microlithiasis

Clinical Features for Testicular Microlithiasis

Sources:
47OMIM
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Clinical features from OMIM:

610441

Drugs & Therapeutics for Testicular Microlithiasis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Testicular Microlithiasis

Genetic Tests for Testicular Microlithiasis

Anatomical Context for Testicular Microlithiasis

Sources:
33MalaCards
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MalaCards organs/tissues related to Testicular Microlithiasis:

33
Spleen, Adrenal gland, Testis, Appendix, Testis germ

Animal Models for Testicular Microlithiasis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Testicular Microlithiasis

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51PubMed
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Articles related to Testicular Microlithiasis:

(show top 50)    (show all 187)
idTitleAuthorsYear
1
Testicular microlithiasis is not a risk factor for the production of antisperm antibody in infertile males. (22928752)
2013
2
Unusual combination of bilateral testicular microlithiasis and tubular ectasia of the rete testis with left intra- and extratesticular varicocele in a 17-year-old boy. (21953309)
2012
3
Extragonadal tumor and testicular microlithiasis. (21633007)
2011
4
Testicular microlithiasis: The importance of self-examination. (21392148)
2011
5
Prevalence of testicular microlithiasis in males with congenital adrenal hyperplasia and its association with testicular adrenal rest tumors. (20407230)
2010
6
Testicular microlithiasis and carcinoma in situ overview and proposed clinical guideline. (19207616)
2009
7
Testicular teratocarcinoma associated with testicular microlithiasis. (17464445)
2008
8
Testicular microlithiasis in siblings: clinical implications. (18246339)
2008
9
Testicular microlithiasis is worrisome in a selected patient population. (18520769)
2008
10
Words of wisdom. Re: a 5-year follow-up study of asymptomatic men with testicular microlithiasis. (19051380)
2008
11
A 5-year followup study of asymptomatic men with testicular microlithiasis. (18289592)
2008
12
Retroiliac ureters with bilateral testicular microlithiasis: simultaneous MDCT visualization of ureters and iliac arteries with biphasic contrast injection. (17377012)
2007
13
Testicular microlithiasis as a familial risk factor for testicular germ cell tumour. (17971766)
2007
14
Testicular microlithiasis: our experience of 10 years. (17592049)
2007
15
Testicular microlithiasis: prevalence and risk of concurrent and interval development of testicular tumor in a referred population. (17602308)
2007
16
Association between testicular microlithiasis, testicular cancer, cryptorchidism and history of ascending testis. (16953910)
2006
17
Testicular microlithiasis identified ultrasonographically in Japanese adult patients: prevalence and associated conditions. (16979721)
2006
18
Testicular microlithiasis heralding mixed germ cell tumor of the testis in a boy. (16553039)
2006
19
Testicular microlithiasis and antisperm antibodies following testicular biopsy in boys with cryptorchidism. (16217379)
2005
20
Heterotopic ossification in testicular microlithiasis. (15351599)
2004
21
Testicular microlithiasis: an unreported feature of McCune-Albright syndrome in males. (15520771)
2004
22
Case of mediastinal seminoma with testicular microlithiasis. (12028303)
2002
23
Testicular microlithiasis: prospective analysis of prevalence and associated tumor. (12147838)
2002
24
Testicular microlithiasis, chemotherapy for stage I seminoma, and chemotherapy for advanced extragonadal germ cell tumors. (16985684)
2002
25
Testicular microlithiasis, a premalignant condition: prevalence, histopathologic findings, and relation to testicular tumor. (11377326)
2001
26
Testicular microlithiasis: is it a benign condition with malignant potential? (11752862)
2001
27
Testicular microlithiasis. (10785850)
2000
28
Testicular microlithiasis in a patient with a mediastinal germ cell tumour. (10964739)
2000
29
The interval of development of testicular carcinoma in a patient with previously demonstrated testicular microlithiasis. (10604361)
2000
30
Testicular microlithiasis and carcinoma in situ. (9933079)
1999
31
Case no. 2. Right testicular pain. Testicular microlithiasis. (10374800)
1999
32
Unilateral testicular microlithiasis. (10431413)
1999
33
Testicular calcifications: incidence, histology and proposed pathological criteria for testicular microlithiasis. (9783919)
1998
34
Cystic dysplasia of the testis: sonographic diagnosis and differentiation from testicular microlithiasis. (9880640)
1998
35
Testicular microlithiasis with mediastinal choriocarcinoma: a case report. (9624568)
1998
36
Testicular microlithiasis and concomitant testicular intraepithelial neoplasia. (9696339)
1998
37
Klinefelter's syndrome associated with testicular microlithiasis and mediastinal germ-cell neoplasm. (9350572)
1997
38
Testicular carcinoma in a patient with previously demonstrated testicular microlithiasis. (8558689)
1996
39
Testicular microlithiasis and subsequent development of metastatic germ cell tumor. (8819375)
1996
40
Testicular microlithiasis associated with seminoma: Gray-scale and color Doppler ultrasound findings. (8961500)
1996
41
Testicular microlithiasis. A case report. (8127302)
1994
42
Testicular microlithiasis. (8140986)
1994
43
Radiological case of the month. Testicular microlithiasis. (7961314)
1994
44
Testicular microlithiasis and epididymo-orchitis: aetiological factor or coincidence? (8181448)
1993
45
Sonographically detected testicular microlithiasis and testicular carcinoma. (8396596)
1993
46
Testicular microlithiasis: sonographic features with pathologic correlation. (1927785)
1991
47
Ultrasonographic findings of testicular microlithiasis associated with intratubular germ cell neoplasia. (1846052)
1991
48
Sonography of testicular microlithiasis. (2660385)
1989
49
Testicular microlithiasis occurring in postorchiopexy testis. (2868557)
1986
50
Testicular microlithiasis with sterility. (7476)
1976

Genetic Variations for Testicular Microlithiasis

Expression for genes affiliated with Testicular Microlithiasis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Testicular Microlithiasis

Search GEO for disease gene expression data for Testicular Microlithiasis.

Pathways for genes affiliated with Testicular Microlithiasis

Compounds for genes affiliated with Testicular Microlithiasis

Sources:
45Novoseek, 11DrugBank, 60Tocris Bioscience, 29IUPHAR, 50PharmGKB, 24HMDB
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Compounds related to Testicular Microlithiasis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1oestriol459.4AFP, CGB
2clomiphene citrate459.3AFP, CGB
3ifosfamide45 1110.3CGB, AFP
4bleomycin45 1110.3AFP, CGB
5mifepristone45 60 29 1112.2AFP, CGB
6vincristine45 50 1111.2CGB, AFP
7thyroxine45 2410.1AFP, CGB
8etoposide45 50 60 1112.1AFP, CGB
9cyclophosphamide45 50 1111.0AFP, CGB
10methotrexate45 50 1110.8AFP, CGB

GO Terms for genes affiliated with Testicular Microlithiasis

Products for genes affiliated with Testicular Microlithiasis

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Sources for Testicular Microlithiasis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet