MCID: TTH004
MIFTS: 26

Tethered Spinal Cord Syndrome malady

Neuronal diseases category
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Summaries for Tethered Spinal Cord Syndrome

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NINDS:43 Tethered spinal cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column.

MalaCards based summary: Tethered Spinal Cord Syndrome, also known as spinal dysraphism, is related to myelomeningocele and occult spinal dysraphism. An important gene associated with Tethered Spinal Cord Syndrome is CASK (calcium/calmodulin-dependent serine protein kinase (MAGUK family)). The compound tyrosine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord.

Wikipedia:65 Tethered spinal cord syndrome (TCS) or occult spinal dysraphism sequence refers to a group of... more...

Aliases & Classifications for Tethered Spinal Cord Syndrome

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Tethered Spinal Cord Syndrome, Aliases & Descriptions:

Name: Tethered Spinal Cord Syndrome 8 43 10
 
Spinal Dysraphism 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology8 DOID:1089
ICD9CM27 741
MeSH34 D016135

Related Diseases for Tethered Spinal Cord Syndrome

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Graphical network of the top 20 diseases related to Tethered Spinal Cord Syndrome:



Diseases related to tethered spinal cord syndrome

Symptoms for Tethered Spinal Cord Syndrome

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Drugs & Therapeutics for Tethered Spinal Cord Syndrome

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Drug clinical trials:

Search ClinicalTrials for Tethered Spinal Cord Syndrome

Search NIH Clinical Center for Tethered Spinal Cord Syndrome

Genetic Tests for Tethered Spinal Cord Syndrome

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Anatomical Context for Tethered Spinal Cord Syndrome

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MalaCards organs/tissues related to Tethered Spinal Cord Syndrome:

32
Spinal cord

Animal Models for Tethered Spinal Cord Syndrome or affiliated genes

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Publications for Tethered Spinal Cord Syndrome

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Articles related to Tethered Spinal Cord Syndrome:

(show all 23)
idTitleAuthorsYear
1
Adult intradural lipoma with tethered spinal cord syndrome. (25073248)
2014
2
Tethered spinal cord syndrome detected during ultrasound for caudal block in a child with single urological anomaly. (23814660)
2013
3
MRI findings, surgical treatment and follow-up of a myelomeningocele with tethered spinal cord syndrome in a cat. (21439878)
2011
4
Electrophysiologically guided untethering of secondary tethered spinal cord syndrome. (20594001)
2010
5
Tethered spinal cord syndrome with symptomatic onset in adulthood. (19951591)
2009
6
Intermittent back and leg pain with numbness. Tethered spinal cord syndrome. (18841738)
2008
7
Tethered spinal cord syndrome--the importance of time for outcomes. (17638158)
2007
8
Tethered spinal cord syndrome. (17615225)
2007
9
Surgical treatment of tethered spinal cord syndrome in a dog with myelomeningocele. (11442238)
2001
10
Congenital tethered spinal cord syndrome in adults. (16749759)
2001
11
Successful pregnancies in a case of retrograde ejaculation associated with tethered spinal cord syndrome. (10955250)
2000
12
Unilateral hyperhidrosis, callosities, and nail dystrophy in a boy with tethered spinal cord syndrome. (9875980)
1998
13
Congenital tethered spinal cord syndrome in adults. (9609288)
1998
14
Urodynamic findings in the tethered spinal cord syndrome: does surgical release improve bladder function? (8996368)
1997
15
Intraoperative monitoring for tethered spinal cord syndrome. (1750002)
1991
16
Pre- and postoperative urodynamic findings in children with tethered spinal cord syndrome. (2022217)
1991
17
The tethered spinal cord syndrome: a correlation of radiological features and peroperative findings in 30 patients. (2717007)
1989
18
MR imaging in the tethered spinal cord syndrome. (2784267)
1989
19
Evaluation of children and young adults with tethered spinal cord syndrome. Utility of spinal and scalp recorded somatosensory evoked potentials. (3738717)
1986
20
Adult onset of tethered spinal cord syndrome due to fibrous diastematomyelia: case report. (3889701)
1985
21
Urinary tract dysfunctions in tethered spinal cord syndrome: improvement after surgical untethering. (3889376)
1985
22
The tethered spinal cord syndrome. (6395542)
1984
23
Neurogenic bladder and the tethered spinal cord syndrome. (458974)
1979

Variations for Tethered Spinal Cord Syndrome

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Expression for genes affiliated with Tethered Spinal Cord Syndrome

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Expression patterns in normal tissues for genes affiliated with Tethered Spinal Cord Syndrome

Search GEO for disease gene expression data for Tethered Spinal Cord Syndrome.

Pathways for genes affiliated with Tethered Spinal Cord Syndrome

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Compounds for genes affiliated with Tethered Spinal Cord Syndrome

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Sources:
44Novoseek
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Compounds related to Tethered Spinal Cord Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tyrosine449.1CASK, ITFG1

GO Terms for genes affiliated with Tethered Spinal Cord Syndrome

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Products for genes affiliated with Tethered Spinal Cord Syndrome

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  • Antibodies
  • Proteins
  • Lysates

Sources for Tethered Spinal Cord Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet