MCID: TTH004

Tethered Spinal Cord Syndrome malady

Summaries for Tethered Spinal Cord Syndrome

Sources:
31NINDS, 44Wikipedia, 22MalaCards
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NINDS: Tethered spinal cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column.31

MalaCards: Tethered Spinal Cord Syndrome, also known as spinal dysraphism, is related to occult spinal dysraphism and currarino syndrome. An important gene associated with Tethered Spinal Cord Syndrome is CHST14 (carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14). Affiliated tissues include spinal cord, and related mouse phenotypes are hearing/vestibular/ear and craniofacial.

Wikipedia: Tethered spinal cord syndrome or occult spinal dysraphism sequence refers to a group of neurological...44 more...

Aliases & Descriptions for Tethered Spinal Cord Syndrome

Sources:
6Disease Ontology, 31NINDS, 8DISEASES, 40SNOMED-CT, 24MeSH, 43UMLS, 19ICD9CM
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Aliases & Descriptions:

tethered spinal cord syndrome 6 31 8
spinal dysraphism 6

External Ids:

ICD9CM19 741

Related Diseases for Tethered Spinal Cord Syndrome

Sources:
13GeneCards, 14GeneDecks
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Diseases related to tethered spinal cord syndrome by text searches and GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1occult spinal dysraphism8.7
2currarino syndrome6.8
3spina bifida6.8

Clinical Features for Tethered Spinal Cord Syndrome

Drugs & Therapeutics for Tethered Spinal Cord Syndrome

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials
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Approved drugs:

Search CenterWatch for tethered spinal cord syndrome

Drug clinical trials:

Search ClinicalTrials for tethered spinal cord syndrome

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Search CenterWatch for tethered spinal cord syndrome

Genetic Tests for Tethered Spinal Cord Syndrome

Anatomical Context for Tethered Spinal Cord Syndrome

Sources:
22MalaCards
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MalaCards organs/tissues related to tethered spinal cord syndrome:

22
Spinal cord

Phenotypes for genes affiliated with Tethered Spinal Cord Syndrome

Sources:
25MGI
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MGI Mouse Phenotypes related to tethered spinal cord syndrome:

25
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1hearing/vestibular/ear phenotypeMP:00053778.9GDF6, CYS1, HOXA1
2craniofacial phenotypeMP:00053828.1LMNB1, CASK, HOXA1, GDF6
3nervous system phenotypeMP:00036317.8LMNB1, CASK, HOXA1, CYS1, GDF6

Publications for genes affiliated with Tethered Spinal Cord Syndrome

Expression for genes affiliated with Tethered Spinal Cord Syndrome

Sources:
1BioGPS
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Expression patterns in normal tissues for genes affiliated with Tethered Spinal Cord Syndrome

Pathways for genes affiliated with Tethered Spinal Cord Syndrome

Compounds for genes affiliated with Tethered Spinal Cord Syndrome

GO Terms for genes affiliated with Tethered Spinal Cord Syndrome

Sources:
12Gene Ontology
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Cellular components related to tethered spinal cord syndrome according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cilium membraneGO:0601709.2CASK, CYS1
2nuclear matrixGO:0163639.1LMNB1, CASK

Sources for Tethered Spinal Cord Syndrome

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS