MCID: TTH004
MIFTS: 26

Tethered Spinal Cord Syndrome malady

Neuronal diseases category

Summaries for Tethered Spinal Cord Syndrome

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45NINDS, 66Wikipedia, 34MalaCards
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NINDS:45 Tethered spinal cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column.

MalaCards: Tethered Spinal Cord Syndrome, also known as spinal dysraphism, is related to myelomeningocele and occult spinal dysraphism. An important gene associated with Tethered Spinal Cord Syndrome is CASK (calcium/calmodulin-dependent serine protein kinase (MAGUK family)). The compound tyrosine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord.

Wikipedia:66 Tethered spinal cord syndrome (TCS) or occult spinal dysraphism sequence refers to a group of... more...

Aliases & Classifications for Tethered Spinal Cord Syndrome

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9Disease Ontology, 45NINDS, 11DISEASES, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

tethered spinal cord syndrome 9 45 11
spinal dysraphism 9


External Ids:

Disease Ontology9 DOID:1089
ICD9CM28 741
MeSH36 D016135

Related Diseases for Tethered Spinal Cord Syndrome

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Tethered Spinal Cord Syndrome:



Diseases related to tethered spinal cord syndrome

Symptoms for Tethered Spinal Cord Syndrome

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Drugs & Therapeutics for Tethered Spinal Cord Syndrome

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Tethered Spinal Cord Syndrome

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Anatomical Context for Tethered Spinal Cord Syndrome

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34MalaCards
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MalaCards organs/tissues related to Tethered Spinal Cord Syndrome:

34
Spinal cord

Animal Models for Tethered Spinal Cord Syndrome or affiliated genes

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Publications for Tethered Spinal Cord Syndrome

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53PubMed
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Articles related to Tethered Spinal Cord Syndrome:

(show all 21)
idTitleAuthorsYear
1
Tethered spinal cord syndrome detected during ultrasound for caudal block in a child with single urological anomaly. (23814660)
2013
2
MRI findings, surgical treatment and follow-up of a myelomeningocele with tethered spinal cord syndrome in a cat. (21439878)
2011
3
Electrophysiologically guided untethering of secondary tethered spinal cord syndrome. (20594001)
2010
4
Tethered spinal cord syndrome with symptomatic onset in adulthood. (19951591)
2009
5
Intermittent back and leg pain with numbness. Tethered spinal cord syndrome. (18841738)
2008
6
Tethered spinal cord syndrome--the importance of time for outcomes. (17638158)
2007
7
Tethered spinal cord syndrome. (17615225)
2007
8
Surgical treatment of tethered spinal cord syndrome in a dog with myelomeningocele. (11442238)
2001
9
Congenital tethered spinal cord syndrome in adults. (16749759)
2001
10
Successful pregnancies in a case of retrograde ejaculation associated with tethered spinal cord syndrome. (10955250)
2000
11
Unilateral hyperhidrosis, callosities, and nail dystrophy in a boy with tethered spinal cord syndrome. (9875980)
1998
12
Congenital tethered spinal cord syndrome in adults. (9609288)
1998
13
Urodynamic findings in the tethered spinal cord syndrome: does surgical release improve bladder function? (8996368)
1997
14
Intraoperative monitoring for tethered spinal cord syndrome. (1750002)
1991
15
Pre- and postoperative urodynamic findings in children with tethered spinal cord syndrome. (2022217)
1991
16
The tethered spinal cord syndrome: a correlation of radiological features and peroperative findings in 30 patients. (2717007)
1989
17
MR imaging in the tethered spinal cord syndrome. (2784267)
1989
18
Adult onset of tethered spinal cord syndrome due to fibrous diastematomyelia: case report. (3889701)
1985
19
Urinary tract dysfunctions in tethered spinal cord syndrome: improvement after surgical untethering. (3889376)
1985
20
The tethered spinal cord syndrome. (6395542)
1984
21
Neurogenic bladder and the tethered spinal cord syndrome. (458974)
1979

Variations for Tethered Spinal Cord Syndrome

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Expression for genes affiliated with Tethered Spinal Cord Syndrome

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tethered Spinal Cord Syndrome

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Pathways for genes affiliated with Tethered Spinal Cord Syndrome

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Compounds for genes affiliated with Tethered Spinal Cord Syndrome

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46Novoseek
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Compounds related to Tethered Spinal Cord Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tyrosine469.1CASK, ITFG1

GO Terms for genes affiliated with Tethered Spinal Cord Syndrome

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Products for genes affiliated with Tethered Spinal Cord Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Tethered Spinal Cord Syndrome

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet