MCID: THR003
MIFTS: 47

Thoracic Aortic Aneurysm malady

Genetic diseases, Cardiovascular diseases, Rare diseases categories

Aliases & Classifications for Thoracic Aortic Aneurysm

About this section
Sources:
10Disease Ontology, 12DISEASES, 2CDC, 47Novoseek, 65UMLS, 36MeSH, 59SNOMED-CT, 29ICD9CM, 42NCIt, 27ICD10
See all sources

Aliases & Descriptions for Thoracic Aortic Aneurysm:

Name: Thoracic Aortic Aneurysm 10 12 2
Aortic Aneurysm, Thoracic 65 36
 
Aortic Aneurysm Thoracic 47


Classifications:



External Ids:

Disease Ontology10 DOID:14004
ICD9CM29 441.2
NCIt42 C27001
MeSH36 D017545
ICD1027 I71.2

Summaries for Thoracic Aortic Aneurysm

About this section
CDC:2 An aortic aneurysm is a balloon-like bulge in the aorta, the large artery that carries blood from the heart through the chest and torso.

MalaCards based summary: Thoracic Aortic Aneurysm, also known as aortic aneurysm, thoracic, is related to loeys-dietz syndrome type 2a and aortic disease. An important gene associated with Thoracic Aortic Aneurysm is FBN1 (Fibrillin 1), and among its related pathways are ALK1 signaling events and Glypican 1 network. Affiliated tissues include the thoracic aorta, heart and smooth muscle, and related mouse phenotypes are craniofacial and vision/eye.

Disease Ontology:10 An aortic aneurysm that is located in the thoracic aorta.

Related Diseases for Thoracic Aortic Aneurysm

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Diseases in the Thoracic Aortic Aneurysm family:

Aortic Aneurysm, Familial Thoracic 7 Aortic Aneurysm, Familial Thoracic 2
Aortic Aneurysm, Familial Thoracic 8 Aortic Aneurysm, Familial Thoracic 6
Aortic Aneurysm, Familial Thoracic 1 Aortic Aneurysm, Familial Thoracic 9
Aortic Aneurysm, Familial Thoracic 4

Diseases related to Thoracic Aortic Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 241)
idRelated DiseaseScoreTop Affiliating Genes
1loeys-dietz syndrome type 2a30.9TGFBR1, TGFBR2
2aortic disease29.5ACTA2, ELN, FBN1, MMP2, MYH11, SMAD3
3aortic aneurysm11.6
4aneurysm11.6
5familial thoracic aortic aneurysm and dissection11.0
6thoracic aortic aneurysms and aortic dissections10.8
7marfan syndrome10.8
8spondylosis10.7
9ischemia10.7
10paraplegia10.7
11dysphagia10.7
12aortic aneurysm, familial thoracic 110.6
13cerebritis10.6
14esophagitis10.6
15bowman's membrane folds or rupture10.6
16coronary aneurysm10.6
17heart aneurysm10.6
18abdominal aortic aneurysm10.5
19aortitis10.5
20coronary artery disease10.5
21coronary heart disease 510.5
22multisystemic smooth muscle dysfunction syndrome10.5
23patent ductus arteriosus10.5
24aortic coarctation10.5
25marfan syndrome/loeys-dietz syndrome/familial thoracic aortic aneurysms and dissections10.5
26acta2-related thoracic aortic aneurysms and aortic dissections10.5
27fbn1-related thoracic aortic aneurysms and aortic dissections10.5
28myh11-related thoracic aortic aneurysms and aortic dissections10.5
29tgfbr1-related thoracic aortic aneurysms and aortic dissections10.5
30tgfbr2-related thoracic aortic aneurysms and aortic dissections10.5
31lung cancer10.4
32loeys-dietz syndrome 110.4
33wiskott-aldrich syndrome10.4
34loeys-dietz syndrome10.4
35mediastinitis10.4
36prkg1-related thoracic aortic aneurysms and aortic dissections10.4
37mfap5-related thoracic aortic aneurysms and aortic dissections10.4
38mylk-related thoracic aortic aneurysms and aortic dissections10.4
39smad3-related thoracic aortic aneurysms and aortic dissections10.4
40coronary heart disease 210.3
41loeys-dietz syndrome 210.3
42aortic aneurysm, familial thoracic 610.3
43loeys-dietz syndrome 510.3
44aortic aneurysm, familial thoracic 410.3
45arthritis10.3
46pulmonary edema10.3
47limb ischemia10.3
48artery disease10.3
49congenital heart disease10.3
50connective tissue disease10.3

Graphical network of the top 20 diseases related to Thoracic Aortic Aneurysm:



Diseases related to thoracic aortic aneurysm

Symptoms for Thoracic Aortic Aneurysm

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Drugs & Therapeutics for Thoracic Aortic Aneurysm

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Drugs for Thoracic Aortic Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IopamidolapprovedPhase 43160166-93-0
Synonyms:
Isovue 200
Isovue 250
 
Isovue 300
Isovue 370
Isovue-m
Isovue-m 200
2
Morphineapproved, investigationalPhase 480557-27-25288826
Synonyms:
(-)(5.alpha.,6.alpha.)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(-)-Heroin hydrochloride
(-)-Morphine
(-)Morphine sulfate
(5R,6S,9R,13S,14R)-4,5-Epoxy-N-methyl-7-morphinen-3,6-diol
(5alpha,6alpha)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
(5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(5alpha,6alpha)-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL
(7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol
(−)-morphine
17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol
4,5alpha-Epoxy-17-methyl-7-morphinen-3,6alpha-diol
4-methyl-(13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol
47106-99-0
57-27-2
6211-15-0 (sulfate (2:1) (salt) pentahydrate)
64-31-3
64-31-3 (sulfate (2:1) (salt) anhydrous)
7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol
7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
8053-16-5
85201-37-2
Apokyn
Astramorph PF
Avinza
BIDD:GT0147
C01516
CCRIS 5762
CHEBI:17303
CHEMBL70
CID5288826
Cube juice
D-(-)-Morphine
DB00295
DEA No. 9300
DepoDur
Depodur
Diacetylmorphine hydrochloride
Diamorphine hydrochloride
Dolcontin
Dreamer
Dulcontin
Duramorph
Duramorph PF
Duromorph
EINECS 200-320-2
Epimorph
HSDB 2134
Hard stuff
Heroin hydrochloride
Heroine hydrochloride
Hocus
Infumorph
 
Kadian
LS-91748
M-Eslon
M.O.S
MOI
MORPHINE SULFATE
MORPHINE, (5A,6A)-7,8-DIDEHYDRO-4,5-EPOXY-17-METHYLMORPHINIAN-3,6-DIOL, MORPHIUM, MORPHIA, DOLCONTIN, DUROMORPH, MORPHINA, NEPENTHE
MS Contin
MS/L
MS/S
MSIR
Meconium
MolPort-003-849-273
Morfina
Morfina [Italian]
Morphia
Morphin
Morphin [German]
Morphina
Morphina [Italian]
Morphine
Morphine Extra-Forte
Morphine Forte
Morphine H.P
Morphine Sulfate
Morphine [BAN]
Morphinism
Morphinum
Morphitec
Morphium
Morpho
Moscontin
Ms Contin
Ms Emma
NSC11441
Nepenthe
O,O'-Diacetylmorphine hydrochloride
OMS Concentrate
Oramorph SR
Ospalivina
RMS
RMS Uniserts
Rescudose
Roxanol
Roxanol 100
Roxanol UD
SDZ 202-250
SDZ202-250
Statex
Statex Drops
Statex SR
UNII-76I7G6D29C
Unkie
l-Morphine
morphine
nchembio.317-comp1
nchembio.64-comp1
3
AcetazolamideapprovedPhase 46159-66-51986
Synonyms:
1424-27-7 (mono-hydrochloride salt)
1yda
1ydb
1ydd
1zsb
2-acetylamino-1,3,4-Thiadiazole-5-sulfonamide
2h4n
3czv
4-Diamox
5-ACETAMIDO-1,3,4-thiadiazole-2-sulfonamide
5-acetylamino-1,3,4-Thiadiazole-2-sulfonamide
5661-25-6
59-66-5
8017-69-4
A 6011
A6011_SIAL
A6011_SIGMA
AB00051906
AC-12779
AC1L1CO5
AI3-52458
AKOS000715163
Acetadiazol
Acetamidothiadiazolesulfonamide
Acetamox
Acetazolam
Acetazolamid
Acetazolamida
Acetazolamida [INN-Spanish]
Acetazolamide
Acetazolamide (AAZ)
Acetazolamide (JP15/USP/INN)
Acetazolamide Apotex Brand
Acetazolamide Chiesi Brand
Acetazolamide Dioptic Brand
Acetazolamide Grin Brand
Acetazolamide ICN Brand
Acetazolamide Jumer Brand
Acetazolamide Llorens Brand
Acetazolamide Medphano Brand
Acetazolamide Novopharm Brand
Acetazolamide Orion Brand
Acetazolamide Sodium
Acetazolamide Sodium, (Sterile)
Acetazolamide Wassermann Brand
Acetazolamide [INN:BAN:JAN]
Acetazolamide, Monosodium Salt
Acetazolamidum
Acetazolamidum [INN-Latin]
Acetazolamine
Acetazoleamide
Acetozalamide
Acétazolamide
Ak Zol
Ak-Zol
AkZol
Apo Acetazolamide
Apo-Acetazolamide
ApoAcetazolamide
Apotex Brand of Acetazolamide
Atenezol
Avva
BAS 01585728
BIDD:GT0643
BPBio1_000007
BSPBio_000005
BSPBio_001788
C06805
C4H6N4O3S2
CAS-59-66-5
CCRIS 5811
CHEBI:27690
CHEMBL20
CID1986
CPD0-1626
CPD000058394
Carbonic Anhydrase Inhibitor 6063
Carbonic Anhydrase Inhibitor No. 6063
Carbonic anhydrase inhibitor 6063
Chiesi Brand of Acetazolamide
Ciba Vision Brand of Acetazolamide
Cidamex
D000086
D00218
DB00819
Dazamide
Defiltran
Dehydratin
Diacarb
Diakarb
Diamox
Diamox (TN)
Diamox Sequels
Didoc
 
Diluran
Dioptic Brand of Acetazolamide
Diuramid
Diuramide
Diureticum-Holzinger
Diureticum-holzinger
Diuriwas
Diutazol
DivK1c_000017
Donmox
Duiramid
EINECS 200-440-5
EU-0100039
Edemox
Eumicton
Fonurit
Glauconox
Glaumox
Glaupax
Glupax
Grin Brand of Acetazolamide
HMS1568A07
HMS1920A05
HMS2091G05
HMS500A19
HSDB 3002
Huma Zolamide
Huma-Zolamide
HumaZolamide
I09-0425
ICN Brand of Acetazolamide
IDI1_000017
Jumer Brand of Acetazolamide
KBio1_000017
KBio2_000358
KBio2_002926
KBio2_005494
KBio3_001288
KBioGR_000558
KBioSS_000358
LS-10227
Llorens Brand of Acetazolamide
Lopac-A-6011
Lopac0_000039
MLS000028435
MLS001148438
Medphano Brand of Acetazolamide
MolPort-001-783-578
Monosodium Salt Acetazolamide
N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
N-[5-(Aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamide
NCGC00015074-01
NCGC00015074-02
NCGC00015074-03
NCGC00015074-06
NCGC00015074-11
NCGC00023455-03
NCGC00023455-04
NCGC00023455-05
NCGC00023455-06
NCGC00023455-07
NINDS_000017
NSC 145177
NSC145177
Natrionex
Nephramid
Nephramide
Novopharm Brand of Acetazolamide
Orion Brand of Acetazolamide
Phonurit
Prestwick0_000003
Prestwick1_000003
Prestwick2_000003
Prestwick3_000003
Prestwick_4
SAM002554883
SBB056640
SK-acetazolamide
SMR000058394
SPBio_000004
SPBio_001926
SPECTRUM1500102
Sk-Acetazolamide
Spectrum2_000082
Spectrum3_000284
Spectrum4_000139
Spectrum5_000738
Spectrum_000018
Storz Brand of Acetazolamide Preparation
Storzolamide
UNII-O3FX965V0I
Vetamox
WLN: T5NN DSJ CSZW EMV1
Wassermann Brand of Acetazolamide
Wyeth Brand of Acetazolamide Preparation
acetazolamide
4
MethylprednisoloneapprovedPhase 4103383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
5
PrednisoloneapprovedPhase 4103350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
6
Mannitolapproved, investigationalPhase 422069-65-8453, 6251
Synonyms:
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
(L)-Mannitol
1,2,3,4,5,6-Hexanehexol
123897-58-5
133-43-7
15719_ALDRICH
15719_RIEDEL
33440_RIEDEL
33440_SIGMA
36413-61-3
4-01-00-02841 (Beilstein Handbook Reference)
5149-40-6
63559_FLUKA
63559_SIGMA
63560_FLUKA
63565_FLUKA
63565_SIGMA
69-65-8
75398-80-0
85085-15-0
87-78-5
AB1002081
AC-12776
AC1L1M49
AC1Q28E5
AI3-19511
AR-1J3861
Ambap69-65-8
BRN 1721898
C00392
C6H14O6
CCRIS 369
CHEBI:16899
CHEMBL689
CID6251
Cordycepate
Cordycepic acid
D-(-)-Mannitol
D-Mannitol
D-Mannitol (JP15)
D-mannite
D-mannitol
D00062
D008353
DL-Mannitol
Diosmol
ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D
EINECS 200-711-8
EINECS 201-770-2
Fraxinine
HSDB 714
Hexahydroxyhexane
Hexanhexol
Invenex
Isotol
LS-1588
LS-89250
M0044
M1902_SIGMA
M4125_SIAL
M8429_SIAL
M9546_SIAL
M9647_SIAL
MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER
MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%
 
MANNITOL 25%
MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%
MLS001335977
MLS001335978
MTL
Manicol
Manitol
Maniton S
Maniton-S
Manna Sugar
Manna sugar
Mannazucker
Mannidex
Mannidex 16700
Mannigen
Mannistol
Mannit
Mannit p
Mannite
Mannitol
Mannitol (USP)
Mannitol (VAN)
Mannitol 10%
Mannitol 10% In Plastic Container
Mannitol 15%
Mannitol 15% In Plastic Container
Mannitol 20%
Mannitol 20% In Plastic Container
Mannitol 5%
Mannitol 5% In Plastic Container
Mannitol [USAN]
Mannitolum
Mannogem 2080
Marine Crystal
Marine crystal
MolPort-003-927-039
Mushroom sugar
NCGC00164246-01
NCI-C50362
NSC 407017
NSC 9256
OSMITROL 10% IN WATER IN PLASTIC CONTAINER
OSMITROL 15% IN WATER IN PLASTIC CONTAINER
OSMITROL 20% IN WATER IN PLASTIC CONTAINER
OSMITROL 5% IN WATER IN PLASTIC CONTAINER
Osmitrol
Osmitrol (TN)
Osmitrol 10% In Water
Osmitrol 15% In Water
Osmitrol 20% In Water
Osmitrol 5% In Water
Osmofundin
Osmosal
Resectisol
Resectisol In Plastic Container
SDM No. 35
SMR000857324
SORBITOL-MANNITOL IN PLASTIC CONTAINER
Sorbitol-Mannitol
TL806434
UNII-3OWL53L36A
ZINC02041302
bmse000099
cpd without stereochemical designation
e 421
e-421
e421
manita
mannitol
7
NicotineapprovedPhase 492354-11-5942, 89594
Synonyms:
(−
(+)-Nicotine
(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(+-)-Nicotine
(-)-3-(1-Methyl-2-pyrrolidyl)pyridine
(-)-3-(N-Methylpyrrolidino)pyridine
(-)-Nicotine
(-)-Nicotine solution
(2S) 3-(1-Methyl-pyrrolidin-2-yl)-pyridine
(R)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(R,S)-Nicotine
(R,S)-nicotine
(RS)-nicotine
(S)-(-)-NICOTINE, 3-[(2S)-1-METHYL-2-PYRROLIDINYL] PYRIDINE
(S)-(-)-Nicotine
(S)-3-(1-methylpyrrolidin-2-yl)pyridine
(S)-3-(N-methylpyrrolidin-2-yl)pyridine
(S)-Nicotine
(±)-nicotine
)-1-Methyl-2-(3-pyridyl)pyrrolidine
)-Nicotine
)-Nicotine solution
1-Methyl-2-(3-pyridal)-Pyrrolidine
1-Methyl-2-(3-pyridal)-pyrrolidene
1-Methyl-2-(3-pyridiyl)pyrrolidine
1-Methyl-2-(3-pyridyl)pyrrolidine
1uw6
2'-beta-H-Nicotine
3-(1-Methyl-2-pyrollidinyl)pyridine
3-(1-Methyl-2-pyrrolidinyl)-Pyridine
3-(1-Methyl-2-pyrrolidinyl)pyridine
3-(1-Methylpyrrolidin-2-yl)pyridine
3-(2-(N-methylpyrrolidinyl))pyridine
3-(N-Methylpyrollidino)pyridine
3-(N-Methylpyrrolidino)pyridine
3-N-Methylpyrrolidine
3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
36733_FLUKA
36733_RIEDEL
434F7990-3240-4A43-ACEC-E6CC1E495FA0
46343_FLUKA
46343_RIEDEL
54-11-5
AC1L3I79
AC1Q3ZOC
AI3-03424
American Fare Nicotine Transdermal System
BB_NC-0777
BIDD:GT0599
BRD-K05395900-322-02-1
Black Leaf
Black Leaf 40
C00745
CCRIS 1637
CHEBI:17688
CHEMBL3
CID89594
CPD000059074
Campbell's Nico-Soap
Careone Nicotine Transdermal System Step 1
Careone Nicotine Transdermal System Step 2
Careone Nicotine Transdermal System Step 3
Caswell No. 597
Commit
D-Nicotine
D03365
DL-tetrahydronicotyrine
Destruxol
Destruxol Orchid Spray
EINECS 200-193-3
ENT 3,424
EPA Pesticide Chemical Code 056702
Emo-Nik
Equaline Nicotine Transdermal System STEP 1
Exchange Select Nicotine Transdermal System STEP 3
Flux Maag
Fumeto bac
Fumetobac
HSDB 1107
Habitrol
Habitrol (TN)
Habitrol Patch Nicotine Transdermal System, Step 1
Habitrol Patch Nicotine Transdermal System, Step 2
Habitrol Patch Nicotine Transdermal System, Step 3
Healthmart Nicotine Transdermal System STEP 1
Healthmart Nicotine Transdermal System STEP 2
Healthmart Nicotine Transdermal System STEP 3
Kroger Nicotine Transdermal System STEP 1
Kroger Nicotine Transdermal System STEP 2
Kroger Nicotine Transdermal System STEP 3
L(-)-nicotine
L-3-(1-Methyl-2-pyrrolidyl)pyridine
L-Nicotine
LS-202
Leader Nicotine
Leader Nicotine Transdermal System STEP 1
Leader Nicotine Transdermal System STEP 2
Leader Nicotine Transdermal System STEP 3
MLS001055457
 
MLS001335905
Mach-Nic
Meijer Nicotine Transdermal System STEP 2
Meijer Nicotine Transdermal System Step 1
Meijer Nicotine Transdermal System Step 3
Methyl-2-pyrrolidinyl)pyridine
Micotine
MolPort-000-744-731
N3876_SIGMA
N5511_FLUKA
N5511_SIGMA
NCGC00090693-01
NCGC00090693-02
NCGC00090693-03
NCGC00090693-04
NCGC00090693-05
NCGC00090693-06
NCGC00090693-07
NCT
NICOTINE AND SALTS
NSC 5065
NSC97238
Niagara P.A. Dust
Nic-Sal
Nico-Dust
Nico-Fume
Nicocide
Nicoderm
Nicoderm CQ
Nicoderm Cq
Nicoderm Patch
Nicorette
Nicorette Plus
Nicotin
Nicotina
Nicotina [Italian]
Nicotine
Nicotine (USP)
Nicotine (compounds related to)
Nicotine Alkaloid
Nicotine Patch
Nicotine Polacrilex
Nicotine TRANSDERMAL SYSTEM
Nicotine Transdermal System PATCH KIT
Nicotine Transdermal System STEP 1
Nicotine Transdermal System STEP 2
Nicotine Transdermal System STEP 3
Nicotine Transdermal System Step 1
Nicotine Transdermal System Step 2
Nicotine Transdermal System Step 3
Nicotine [BSI:ISO]
Nicotine [UN1654]
Nicotine [UN1654] [Poison]
Nicotine [USAN]
Nicotine transdermal system
Nicotrol
Nicotrol (professional Sample)
Nicotrol Inhaler
Nicotrol Ns
Nictoine patch
Nikotin
Nikotin [German]
Nikotyna
Nikotyna [Polish]
Ortho N-4 Dust
Ortho N-5 Dust
PDSP1_000113
PDSP1_000465
PDSP2_000463
PDSP2_000555
Prostep
R)-(+)-Nicotine
RCRA waste no. P075
RCRA waste number P075
Rite Aid Nicotine Transdermal System Step 1
Rite Aid Nicotine Transdermal System Step 2
Rite Aid Nicotine Transdermal System Step 3
SAM002564224
SDCCGMLS-0066911.P001
SMR000059074
Safeway Nicotine Transdermal System STEP 1
Safeway Nicotine Transdermal System STEP 2
Safeway Nicotine Transdermal System STEP 3
Smart Sense Nicotine
Sunmark Nicotine
Sunmark Nicotine Transdermal System STEP 1
Sunmark Nicotine Transdermal System STEP 2
Sunmark Nicotine Transdermal System STEP 3
Tendust
Transdermal Nicotine
UN1654
a -N-Methylpyrrolidine
a-N-Methylpyrrolidine
alpha-N-Methylpyrrolidine
beta-Pyridyl-alpha-N-methyl pyrrolidine
beta-Pyridyl-alpha-N-methylpyrrolidine
bmse000105
delta-Nicotine
nicotine
nicotine replacement patch
8
DexmedetomidineapprovedPhase 4420113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
9
IodinePhase 44597553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
10cadexomer iodinePhase 4425
11Prednisolone hemisuccinatePhase 41033
12Prednisolone phosphatePhase 41033
13Methylprednisolone acetatePhase 41033
14Prednisolone acetatePhase 41033
15Methylprednisolone HemisuccinatePhase 41033
16Adrenergic alpha-2 Receptor AgonistsPhase 4732
17histidineNutraceuticalPhase 431
18TryptophanNutraceuticalPhase 451
19
LosartanapprovedPhase 3265114798-26-43961
Synonyms:
(2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
114798-26-4
124750-99-8 (mono-potassium salt)
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl-1H-imidazole-5-methanol
2-N-Butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5ylphenyl)benzyl]imidazole-5-methanol
2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-n-butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]methyl]imidazole
AC1L1H3Q
BIDD:GT0286
BRD-K76205745-001-02-5
BSPBio_002695
C07072
C22H23ClN6O
CHEBI:6541
CHEMBL191
CID3961
CL23623
Cozaar
D08146
DB00678
DUP 89
DuP 89
DuP-753
HMS1922J13
HMS2093E22
Hyzaar
I14-9710
Jsp001094
KBio2_002193
 
KBio2_004761
KBio2_007329
KBio3_001915
KBioGR_001611
KBioSS_002193
L000351
LOSARTAN POTASSIUM
LS-78746
Lacidipine
Lortaan
Losartan
Losartan (INN)
Losartan Potassium
Losartan [INN:BAN]
Losartan monopotassium salt
Losartic
Losartic (TN)
MK-954
MK954
MolPort-003-666-553
NCGC00095125-01
NCGC00095125-02
NCGC00095125-03
Oprea1_644635
SPBio_001893
SPECTRUM1504268
Spectrum2_001677
Spectrum3_000998
Spectrum4_001126
Spectrum5_001466
Spectrum_001713
UNII-JMS50MPO89
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
losartan
losartan potassium
20Angiotensin II Type 1 Receptor BlockersPhase 3928
21Natriuretic Peptide, BrainPhase 3167
22
Angiotensin IIPhase 398568521-88-0, 11128-99-7172198
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
23
NicardipineapprovedPhase 22855985-32-54474
Synonyms:
2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridine-3,5-dicarboxylate
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(benzylmethylamino)ethyl methyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-[methyl(phenylmethyl)amino]ethyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-(benzylmethylamino)ethyl methyl ester
5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
55985-32-5
AB00514658
AC-19947
AC1L1I8Y
AKOS001637090
Ambap55985-32-5
BIDD:GT0621
BPBio1_000623
BRD-A26711594-001-02-7
BRD-A26711594-003-05-6
BRN 0504321
BSPBio_000565
BSPBio_001389
BSPBio_002943
Bio1_000088
Bio1_000577
Bio1_001066
Bio2_000109
Bio2_000589
C07264
C26H29N3O6
CBiol_001802
CHEBI:507549
CHEMBL1484
CID4474
Cardene
Cardene (TN)
Cardene IV
Cardene Iv
Cardene SR
D08270
DB00622
DivK1c_000540
EINECS 259-932-3
HMS1791F11
HMS1989F11
HMS2089C09
IDI1_000540
IDI1_033859
KBio1_000540
 
KBio2_000109
KBio2_001852
KBio2_002677
KBio2_004420
KBio2_005245
KBio2_006988
KBio3_000217
KBio3_000218
KBio3_002443
KBioGR_000109
KBioGR_000744
KBioSS_000109
KBioSS_001852
L000715
LS-131263
Lopac0_000809
MolPort-002-484-049
NCGC00015747-06
NCGC00162262-01
NCGC00162262-02
NCGC00162262-03
NCGC00162262-04
NINDS_000540
Nicardipine (INN)
Nicardipine Hydrochloride
Nicardipine LA
Nicardipine [INN:BAN]
Nicardipino
Nicardipino [INN-Spanish]
Nicardipinum
Nicardipinum [INN-Latin]
Oprea1_436998
Prestwick0_000383
Prestwick1_000383
Prestwick2_000383
Prestwick3_000383
SPBio_001490
SPBio_002486
Spectrum2_001415
Spectrum3_001452
Spectrum4_000422
Spectrum5_001320
Spectrum_001372
UNII-CZ5312222S
Y-93
methyl 2-[methyl(phenylmethyl)amino]ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
nicardipine
24Calcium, DietaryPhase 23529
25
Heparinapproved, investigational6729005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
26Fluorodeoxyglucose F18340
27Deoxyglucose94
28Thrombin257
29calcium heparin672
30
31CalamusNutraceutical312

Interventional clinical trials:

(show top 50)    (show all 114)
idNameStatusNCT IDPhase
1Endovascular Repair of Descending Thoracic Aortic AneurysmsCompletedNCT00802984Phase 4
2Effects of a Surgery-induced Peripheral Inflammatory Response on the Blood Brain BarrierCompletedNCT00878371Phase 4
3Thoracoabdominal Arortic CTA StudyCompletedNCT02291718Phase 4
4Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm RepairCompletedNCT02677532Phase 4
5Prevalence of Abdominal Aortic Aneurysm in Patients Undergoing Coronary AngiographyCompletedNCT01239225Phase 4
6Coronary CT Angiography in Aneurysms Repaired With Open or Endovascular ApproachCompletedNCT01211548Phase 4
7Immunonutrition and Thoracoabdominal Aorta Aneurysm RepairRecruitingNCT00339053Phase 4
8Vasculopathic Injury and Plasma as Endothelial Rescue - OCTAplas Trial (EudraCT no. 2014-000452-28)RecruitingNCT02253082Phase 4
9Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery SurgeryRecruitingNCT01889498Phase 4
10Bloodtranfusions After Aortic SurgeryRecruitingNCT02299947Phase 4
11CUstodiol Versus RInger: whaT Is the Best Agent?RecruitingNCT02327611Phase 4
12Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)Active, not recruitingNCT00805948Phase 4
13Effect of Intraoperative Dexmedetomidine on LungNot yet recruitingNCT02678728Phase 4
14Dexmedetomidine for Postoperative Sedation in Patients Undergoing Repair of Thoracoabdominal Aortic AneurysmsTerminatedNCT00409344Phase 4
15Long-term Benefit of Aortic Stent-graft in Patients With Distal Aortic DissectionTerminatedNCT01354119Phase 4
16ATLANTIS:Extensive Type A Dissections and Thoracic/ Thoraco-Abdominal Aneurysms Repair With LupiAe Hybrid TechNiqueWithdrawnNCT01107366Phase 4
17VALOR: The Talent Thoracic Stent Graft System Clinical StudyCompletedNCT00604799Phase 2, Phase 3
18To Evaluate the Safety and Efficacy for GORE TAG Thoracic Endoprosthesis in the Treatment of Thoracic Aortic DiseaseCompletedNCT00757003Phase 3
19ARBITER-II: Aorfix™ Bifurcated Safety and Performance Trial: Phase II, Angulated VesselsCompletedNCT00442065Phase 2, Phase 3
20The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal FailureRecruitingNCT00110201Phase 3
21Valiant Evo US Clinical TrialNot yet recruitingNCT02652949Phase 3
22Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan SyndromeTerminatedNCT00763893Phase 3
23Study of GSK1278863 to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm RepairCompletedNCT01920594Phase 2
24GORE TAG® Thoracic Endoprosthesis - 45 mm for the Treatment of Aneurysms of the Descending Thoracic AortaCompletedNCT00608829Phase 2
25Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac SurgeryCompletedNCT00903604Phase 2
26Evaluation of the Vascutek Hybrid Graft for Use in the Replacement of the Aortic Arch and Concomitant Treatment of an Aneurysm/Dissection of the Descending Aorta in the Frozen Elephant Trunk ProcedureCompletedNCT01541410Phase 1, Phase 2
27Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic AneurysmRecruitingNCT00483249Phase 1, Phase 2
28Evaluation of Branch Endografts in the Treatment of Aortic AneurysmsRecruitingNCT01524211Phase 2
29Phase II Study of the Safety and Efficacy of the Relay Thoracic Stent-GraftActive, not recruitingNCT00435942Phase 2
30NICardipine Neuroprotection in AortiC Surgery (NICNACS)TerminatedNCT00508118Phase 2
31Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac SurgeryTerminatedNCT00628264Phase 2
32South American Thoracic Stent-Graft StudyCompletedNCT01082172Phase 1
33Endovascular Exclusion of Thoracic Aortic AneurysmsRecruitingNCT00583817Phase 1
34ENTRUST - TAArget® Thoracic Stent Graft Clinical TrialActive, not recruitingNCT01033214Phase 1
35Phase II Clinical Study of the Safety and Efficacy of the Relay Thoracic Stent-GraftApproved for marketingNCT01327742
36STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular GraftCompletedNCT00111176
37Valor II: The Valiant Thoracic Stent Graft System Clinical StudyCompletedNCT00413231
38Evaluation of the GORE TAG Thoracic Endoprosthesis in the Treatment of AneurysmsCompletedNCT00590759
39Evaluation of the Safety and Efficacy of the Multilayer StentCompletedNCT01756911
40Post Market Surveillance Study Evaluating BioFoam Surgical Matrix in Cardiovascular SurgeryCompletedNCT02164201
41A Comparison of Renal Perfusion in Thoracoabdominal Aortic Aneurysm (TAAA) RepairCompletedNCT00691756
42Risk Factors in the Initial Presentation of Specific Cardiovascular Disease SyndromesCompletedNCT01804439
43Radiation Dose From Computed Tomography Before and After Implementation of a High Pitch Dual Spiral TechniqueCompletedNCT01111760
44Computed Tomography Dose Reduction Using Sequential or Fast Pitch Sprial TechniqueCompletedNCT01272453
45Reduction of Myocardial Infarction by Preconditioning in Patients With Ruptured Abdominal Aortic AneurysmCompletedNCT00883363
46Endoprosthesis Treatment Effects on Human Abdominal Aorta Aneurysms (AAA) Metabolic ActivityCompletedNCT01253252
47Analysis of Risk Factors for Death After Blunt Traumatic Rupture of the Thoracic AortaCompletedNCT01632774
48Limb Remote Ischemic Preconditioning Reduces Heart and Lung Injury After Abdominal Aortic Aneurysm RepairCompletedNCT01344239
49Screening Programme for Abdominal Aortic Aneurysm by Hand-Held-Ultrasonography in Primary Health CareCompletedNCT01882634Phase 0
50Human Bronchial Microdialysis in Open Aortic Aneurysm RepairCompletedNCT01322295

Search NIH Clinical Center for Thoracic Aortic Aneurysm


Cochrane evidence based reviews: Aortic Aneurysm, Thoracic

Genetic Tests for Thoracic Aortic Aneurysm

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Anatomical Context for Thoracic Aortic Aneurysm

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MalaCards organs/tissues related to Thoracic Aortic Aneurysm:

33
Heart, Smooth muscle, Lung, Spinal cord, Testes, Thyroid, Kidney

FMA organs/tissues related to Thoracic Aortic Aneurysm:

16
The thoracic aorta

Animal Models for Thoracic Aortic Aneurysm or affiliated genes

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MGI Mouse Phenotypes related to Thoracic Aortic Aneurysm:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.7FBN1, MMP2, SMAD3, TGFB2, TGFBR2
2MP:00053918.4ACTA2, MMP2, SMAD3, TGFB2, TGFBR2
3MP:00020067.8MMP1, MMP2, SMAD3, TGFBR1, TGFBR2
4MP:00053907.7ELN, FBN1, MMP2, SMAD3, TGFB2, TGFBR1
5MP:00053787.7FBN1, MMP2, MYH11, SMAD3, TGFB2, TGFBR1
6MP:00053887.4ELN, FBN1, MMP2, MYH11, TGFB2, TGFBR1
7MP:00053697.3ACTA2, ELN, FBN1, MMP2, MYH11, TGFB2
8MP:00107687.2ELN, FBN1, MMP2, MYH11, SMAD3, TGFB2
9MP:00053877.1FBN1, MMP1, MMP2, SMAD3, TGFB2, TGFBR1
10MP:00053856.9ACTA2, ELN, FBN1, MMP2, MYH11, SMAD3
11MP:00053765.9ELN, FBN1, MMP1, MMP2, MYH11, SMAD3

Publications for Thoracic Aortic Aneurysm

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Articles related to Thoracic Aortic Aneurysm:

(show top 50)    (show all 603)
idTitleAuthorsYear
1
Phenotypic switching of vascular smooth muscle cells in animal model of rat thoracic aortic aneurysm. (25829166)
2015
2
Mechanical stretch-induced endoplasmic reticulum stress, apoptosis and inflammation contribute to thoracic aortic aneurysm and dissection. (25788370)
2015
3
Routine Genetic Testing for Thoracic Aortic Aneurysm and Dissection in a Clinical Setting. (26188975)
2015
4
Thoracic endovascular aortic repair for ruptured descending thoracic aortic aneurysm. (25545234)
2015
5
Successful Emergent Endovascular Repair of a Ruptured Mycotic Thoracic Aortic Aneurysm. (25733223)
2015
6
Re: "Endovascular repair of a right-sided thoracic aortic aneurysm with Kommerell diverticulum and aberrant left subclavian artery". (24675060)
2014
7
Successful long-term management of iris flocculi and miosis in a patient with a strong family history of thoracic aortic aneurysms and dissections associated with an MYH11 mutation. (24921172)
2014
8
Left untreated: the natural course of a thoracic aortic aneurysm. (23929542)
2013
9
Hybrid treatment for thoracic aortic aneurysm combined with aberrant right subclavian artery. (23407812)
2013
10
Endovascular repair of descending thoracic aortic aneurysm in patient with Wiskott-Aldrich syndrome. (23643280)
2013
11
Appearance of thoracic aortic aneurysm on myocardial perfusion imaging. (23177336)
2013
12
Open-stent grafting with a GORE TAG thoracic endoprosthesis for an extended severely atheromatous thoracic aortic aneurysm: report of a case. (22983735)
2013
13
Antero-lateral partial sternotomy for extensive thoracic aortic aneurysm. (23243031)
2013
14
Endovascular treatment of thoracic aortic aneurysm: a single-center experience. (23790762)
2013
15
Hybrid approach to treat total thoracic aortic aneurysm in a patient undergoing emergency surgery for descending aortic rupture. (23585222)
2013
16
Late neurological recovery of paraplegia after endovascular repair of an infected thoracic aortic aneurysm. (23146426)
2013
17
Repair of thoracic aortic aneurysm due to noninfectious aortitis. (22309320)
2012
18
The modified chimney technique with a thoracic aortic stent graft to preserve the blood flow of the left common carotid artery for treating descending thoracic aortic aneurysm and dissection. (22701139)
2012
19
Management of a parturient with a thoracic aortic aneurysm. (21441805)
2011
20
Superior nationwide outcomes of endovascular versus open repair for isolated descending thoracic aortic aneurysm in 11,669 patients. (20951252)
2010
21
Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome. (20189193)
2010
22
Elevation of ADAM10, ADAM17, MMP-2 and MMP-9 expression with media degeneration features CaCl2-induced thoracic aortic aneurysm in a rat model. (20621845)
2010
23
Meta-analysis of open versus endovascular repair for ruptured descending thoracic aortic aneurysm. (20347700)
2010
24
Ascending thoracic aortic aneurysms are associated with compositional remodeling and vessel stiffening but not weakening in age-matched subjects. (19154911)
2009
25
Endovascular repair of descending thoracic aortic aneurysm: review of literature. (20226348)
2009
26
Single-stage repair of extended thoracic aortic aneurysm. (19074457)
2009
27
I-131 visualization of thoracic aortic aneurysm after radioiodine administration for thyroid carcinoma. (18645377)
2008
28
Successful descending thoracic aortic aneurysm repair during a twin pregnancy: case report and literature review. (17349343)
2007
29
Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus. (16444274)
2006
30
Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation. (17000289)
2006
31
Primary lymphoma of the aorta presenting as a descending thoracic aortic aneurysm. (16181902)
2005
32
F-18 FDG PET imaging features of a perigraft leak and thrombus in a patient with dissecting descending thoracic aortic aneurysm. (15483501)
2004
33
Simultaneous endovascular exclusion of thoracic aortic aneurysm with open abdominal aortic aneurysm repair. (15350571)
2004
34
Thoracic aortic aneurysm with aortobronchial fistula: a thirteen-year experience. (15024377)
2004
35
Cardiopulmonary bypass for thoracic aortic aneurysm: a report on 488 cases. (15095837)
2004
36
Emergent surgery for 3 aged patients who refused elective operation for thoracic aortic aneurysm. (14529161)
2003
37
Salvage of an acutely ruptured thoracic aortic aneurysm during CPR. (12166844)
2002
38
Magnetic resonance imaging of thoracic aortic aneurysm and dissection. (11715325)
2001
39
Ischemic transverse myelopathy after endovascular repair of a thoracic aortic aneurysm. (11491268)
2001
40
Special cerebral perfusion in surgery for the ruptured thoracic aortic aneurysm. (10522790)
1999
41
Descending thoracic aortic aneurysm: thoracic CT findings after endovascular stent-graft placement. (10405738)
1999
42
Geriatrics photo quiz. Thoracic aortic aneurysm. (9307570)
1997
43
Liquefaction of thrombus in thoracic aortic aneurysm: MR findings. (7785614)
1995
44
Chronic posttraumatic thoracic aortic aneurysm presenting with dysphagia. (7674415)
1995
45
Thoracic aortic aneurysm and rupture in giant cell arteritis. A descriptive study of 41 cases. (7864947)
1994
46
Aortoesophageal fistula secondary to thoracic aortic aneurysm repair. (8282742)
1993
47
Functional aortic coarctation caused by thrombosis within a thoracic aortic aneurysm. (1572887)
1992
48
Ruptured thoracic aortic aneurysm with aorto-esophageal fistula. (3950966)
1986
49
Early diagnosis of tuberculous thoracic aortic aneurysm by computerized axial tomography. (699543)
1978
50
Traumatic thoracic aortic aneurysm. Report of a case with rupture into the left subpleural space. (5016736)
1972

Variations for Thoracic Aortic Aneurysm

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Expression for genes affiliated with Thoracic Aortic Aneurysm

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Search GEO for disease gene expression data for Thoracic Aortic Aneurysm.

Pathways for genes affiliated with Thoracic Aortic Aneurysm

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Pathways related to Thoracic Aortic Aneurysm according to GeneCards Suite gene sharing:

(show all 50)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7TGFBR1, TGFBR2
29.7TGFBR1, TGFBR2
3
p38 MAPK Signaling Pathway (WikiPathways)
Show member pathways
9.5TGFBR1, TGFBR2
4
Show member pathways
9.3SMAD3, TGFBR1, TGFBR2
59.3SMAD3, TGFBR1, TGFBR2
69.3SMAD3, TGFBR1, TGFBR2
7
Show member pathways
9.3SMAD3, TGFBR1, TGFBR2
8
Show member pathways
9.3SMAD3, TGFBR1, TGFBR2
99.3SMAD3, TGFBR1, TGFBR2
109.3SMAD3, TGFBR1, TGFBR2
11
Show member pathways
9.3SMAD3, TGFBR1, TGFBR2
129.3SMAD3, TGFBR1, TGFBR2
139.2TGFB2, TGFBR1, TGFBR2
149.2TGFB2, TGFBR1, TGFBR2
159.2TGFB2, TGFBR1, TGFBR2
169.1MMP1, MMP2
179.1MMP1, MMP2
189.1MMP1, MMP2
199.0ELN, MMP1
20
Show member pathways
9.0ELN, FBN1, TGFB2
21
Angiogenesis (CST)
Show member pathways
9.0ELN, FBN1, TGFB2
228.9MMP1, TGFBR1, TGFBR2
23
Show member pathways
8.8ACTA2, TGFB2, TGFBR1, TGFBR2
24
Show member pathways
8.8MMP2, SMAD3, TGFBR1, TGFBR2
25
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
268.8SMAD3, TGFB2, TGFBR1, TGFBR2
27
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
28
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
29
TGF-beta Signaling Pathway (sino)
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
30
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
318.8SMAD3, TGFB2, TGFBR1, TGFBR2
32
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
33
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
34
TGF-beta signaling pathway (KEGG)
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
35
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
368.8SMAD3, TGFB2, TGFBR1, TGFBR2
378.8SMAD3, TGFB2, TGFBR1, TGFBR2
388.8SMAD3, TGFB2, TGFBR1, TGFBR2
398.8SMAD3, TGFB2, TGFBR1, TGFBR2
40
Show member pathways
8.8SMAD3, TGFB2, TGFBR1, TGFBR2
41
Show member pathways
8.5ACTA2, MYH11, TGFB2, TGFBR1, TGFBR2
428.4ACTA2, SMAD3, TGFB2, TGFBR1, TGFBR2
43
Show member pathways
8.2ACTA2, ELN, FBN1, TGFB2, TGFBR1
44
Show member pathways
8.0ACTA2, MYH11, SMAD3, TGFB2, TGFBR1, TGFBR2
45
Show member pathways
7.7ELN, FBN1, MMP1, MMP2, TGFB2
467.4MMP1, MMP2, SMAD3, TGFB2, TGFBR1, TGFBR2
477.4MMP1, MMP2, SMAD3, TGFB2, TGFBR1, TGFBR2
48
Show member pathways
7.1ACTA2, ELN, FBN1, MYH11, SMAD3, TGFB2
49
Show member pathways
7.0ACTA2, MMP1, MMP2, SMAD3, TGFB2, TGFBR1
50
Show member pathways
6.2ACTA2, ELN, FBN1, MMP1, MMP2, MYH11

GO Terms for genes affiliated with Thoracic Aortic Aneurysm

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Cellular components related to Thoracic Aortic Aneurysm according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transforming growth factor beta receptor homodimeric complexGO:007002210.2TGFBR1, TGFBR2
2receptor complexGO:00432359.4SMAD3, TGFBR1, TGFBR2
3extracellular matrixGO:00310128.3FBN1, MMP1, MMP2, TGFB2
4proteinaceous extracellular matrixGO:00055788.1ELN, FBN1, MMP1, MMP2

Biological processes related to Thoracic Aortic Aneurysm according to GeneCards Suite gene sharing:

(show all 28)
idNameGO IDScoreTop Affiliating Genes
1response to cholesterolGO:007072310.3TGFBR1, TGFBR2
2peptidyl-threonine phosphorylationGO:001810710.3TGFBR1, TGFBR2
3positive regulation of epithelial cell migrationGO:001063410.2TGFB2, TGFBR2
4lens development in camera-type eyeGO:000208810.2TGFBR1, TGFBR2
5activin receptor signaling pathwayGO:003292410.2SMAD3, TGFBR1
6neuron fate commitmentGO:004866310.2TGFB2, TGFBR1
7regulation of transforming growth factor beta2 productionGO:003290910.1SMAD3, TGFB2
8gastrulationGO:000736910.1SMAD3, TGFBR2
9cardiac epithelial to mesenchymal transitionGO:006031710.1TGFB2, TGFBR1
10epithelial to mesenchymal transitionGO:000183710.1TGFB2, TGFBR1
11positive regulation of epithelial to mesenchymal transitionGO:001071810.1SMAD3, TGFB2
12face morphogenesisGO:00603259.9MMP2, TGFB2
13negative regulation of transforming growth factor beta receptor signaling pathwayGO:00305129.8SMAD3, TGFBR1, TGFBR2
14pathway-restricted SMAD protein phosphorylationGO:00603899.8TGFB2, TGFBR1, TGFBR2
15signal transduction by protein phosphorylationGO:00230149.8TGFB2, TGFBR1, TGFBR2
16in utero embryonic developmentGO:00017019.7SMAD3, TGFBR1, TGFBR2
17embryonic cranial skeleton morphogenesisGO:00487019.7SMAD3, TGFBR1, TGFBR2
18collagen fibril organizationGO:00301999.6TGFB2, TGFBR1
19cell cycle arrestGO:00070509.5SMAD3, TGFB2, TGFBR1
20angiogenesisGO:00015259.4MMP2, TGFB2, TGFBR1
21response to hypoxiaGO:00016669.3MMP2, SMAD3, TGFB2
22heart developmentGO:00075079.1FBN1, TGFB2, TGFBR1, TGFBR2
23positive regulation of gene expressionGO:00106289.0ACTA2, SMAD3, TGFB2, TGFBR1
24skeletal system developmentGO:00015019.0FBN1, SMAD3, TGFB2, TGFBR1
25transforming growth factor beta receptor signaling pathwayGO:00071799.0SMAD3, TGFB2, TGFBR1, TGFBR2
26wound healingGO:00420608.8SMAD3, TGFB2, TGFBR1, TGFBR2
27extracellular matrix disassemblyGO:00226178.1ELN, FBN1, MMP1, MMP2
28extracellular matrix organizationGO:00301987.7ELN, FBN1, MMP1, MMP2, TGFB2

Molecular functions related to Thoracic Aortic Aneurysm according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1transforming growth factor beta-activated receptor activityGO:000502410.1TGFBR1, TGFBR2
2type III transforming growth factor beta receptor bindingGO:003471410.0TGFB2, TGFBR2
3transmembrane receptor protein serine/threonine kinase activityGO:00046759.9TGFBR1, TGFBR2
4type II transforming growth factor beta receptor bindingGO:00051149.8TGFB2, TGFBR1
5transforming growth factor beta receptor bindingGO:00051609.6SMAD3, TGFB2
6transforming growth factor beta bindingGO:00504319.6TGFBR1, TGFBR2
7receptor signaling protein serine/threonine kinase activityGO:00047029.3TGFB2, TGFBR1, TGFBR2
8SMAD bindingGO:00463329.3SMAD3, TGFBR1, TGFBR2

Sources for Thoracic Aortic Aneurysm

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet