TAO
MCID: THR006
MIFTS: 77

Thromboangiitis Obliterans (TAO) malady

Rare diseases, Cardiovascular diseases, Nephrological diseases, Bone diseases, Blood diseases categories
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Summaries for Thromboangiitis Obliterans

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Sources:
43NIH Rare Diseases, 65Wikipedia, 47OMIM, 33MalaCards
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Fully expand this MalaCard
NIH Rare Diseases:43 Buerger disease is a disease that causes obstruction of the blood vessels of the hands and feet. it is caused by vasculitis, which is an inflammation of blood vessels. the blood vessels of the hands and feet are especially affected, becoming constricted or totally blocked. this reduces blood flow to the tissues of hands and feet, resulting in pain and eventually damage. last updated: 11/19/2009

MalaCards: Thromboangiitis Obliterans, also known as buerger disease, is related to thrombophlebitis and arteriosclerosis obliterans, and has symptoms including acute ischemia of the lower limbs, arterial pulse abolition and arterial embolism/thrombosis. An important gene associated with Thromboangiitis Obliterans is APOH (apolipoprotein H (beta-2-glycoprotein I)), and among its related pathways are Development Leptin signaling via JAK STAT and MAPK cascades and Endothelin. The drugs isoxsuprine and tolazoline and the compounds carvedilol and gliclazide have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and endothelial, and related mouse phenotypes are endocrine/exocrine gland and vision/eye.

Wikipedia:65 Thromboangiitis obliterans (also known as Buerger\'s disease, Buerger disease [English /b?r??r/; German... more...

Description from OMIM:47 211480

Aliases & Classifications for Thromboangiitis Obliterans

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Sources:
8Disease Ontology, 43NIH Rare Diseases, 49Orphanet, 31LifeMap Discovery™, 62UMLS, 45Novoseek, 47OMIM, 27ICD9CM, 58SNOMED-CT, 40NCIt, 35MeSH, 59SNOMED-CT via Orphanet, 26ICD10 via Orphanet, 25ICD10
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Classifications:



Characteristics (Orphanet epidemiological data):

49
thromboangiitis obliterans:
Prevalence: 1-5/10000; Age of onset: Adulthood; Age of death: Normal


Aliases & Descriptions:

thromboangiitis obliterans 8 43 49 31 62
buerger disease 43 45 49 47
buerger's disease 8 43
inflammatory occlusive peripheral vascular disease 43
occlusive peripheral vascular disease 43
thromboangiitis obliterans nos 8
presenile gangrene 8
tao 43


External Ids:

Disease Ontology8 DOID:12918
ICD9CM27 443.1
NCIt40 C35070
MeSH35 D013919
OMIM47 211480
SNOMED-CT via Orphanet59 52403007
ICD10 via Orphanet26 I73.1
ICD1025 I73.1

Related Diseases for Thromboangiitis Obliterans

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17GeneCards, 18GeneDecks
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Diseases related to Thromboangiitis Obliterans via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 140)
idRelated DiseaseScoreTop Affiliating Genes
1thrombophlebitis31.0APOH
2arteriosclerosis obliterans31.0VCAM1, ICAM1
3vascular disease30.9TIMP1, APOH
4arteriosclerosis30.9EDN1, ICAM1, VCAM1, NOS3, SERPINE1
5ischemia30.8NOS3, EDN1, SELE, ICAM1, PLAT
6vasculitis30.5VCAM1, APOH, SELE, ICAM1, SERPINB1
7peripheral vascular disease30.4SELE
8impotence30.4NOS3, EDN1
9atherosclerosis30.4ICAM1, EDN1, APOH, SELE, TIMP1, PLAT
10pulmonary embolism30.3APOH, PLAT
11venous thrombosis30.3PLAT, APOH, SERPINE1
12arthritis30.3TIMP1, SELE, MMP9, ICAM1
13thrombophilia30.2PLAT, SELE, SERPINE1, APOH
14hyperhomocysteinemia30.1PLAT, NOS3, VCAM1, SERPINE1, APOH, SELE
15obesity30.0SERPINE1, NOS3, HTR2A, SELE
16diabetes mellitus29.6ICAM1, NOS3, MMP9, EDN1, SERPINE1, PLAT
17cerebritis10.7
18endotheliitis10.6
19critical limb ischemia10.4
20limb ischemia10.4
21peripheral artery disease10.4
22artery disease10.4
23thyroiditis10.3
24chronic venous insufficiency10.2
25nicotine dependence10.2
26paronychia10.2
27cellulitis10.2
28diarrhea10.2
29dilated cardiomyopathy10.2
30eosinophilia10.2
31venous insufficiency10.2
32cogan's syndrome10.2
33rheumatic disease10.2
34blindness10.2
35retinal artery occlusion10.1APOH
36retinal vein occlusion10.1APOH
37low renin hypertension10.1EDN1
38carotid artery thrombosis10.1SERPINE1
39systemic scleroderma10.1EDN1
40heart valve disease10.1HTR2A, APOH
41malaria10.1ICAM1
42diabetic angiopathy10.1EDN1, SELE
43acute chest syndrome10.1NOS3, VCAM1
44plummer's disease10.1ICAM1, SELE
45cardiac rupture10.1PLAT
46central retinal artery occlusion10.1PLAT
47protein s deficiency10.1SERPINE1, APOH
48prinzmetal's variant angina10.1NOS3, EDN1
49hellp syndrome10.1APOH, SERPINE1
50immunoglobulin a vasculitis10.1ICAM1, VCAM1

Graphical network of the top 20 diseases related to Thromboangiitis Obliterans:



Diseases related to thromboangiitis obliterans

Symptoms for Thromboangiitis Obliterans

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47OMIM, 49Orphanet
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Symptoms by clinical synopsis from OMIM:

211480

Clinical features from OMIM:

211480

Symptoms:

49 (show all 12)
  • acute ischemia of the lower limbs
  • arterial pulse abolition
  • arterial embolism/thrombosis
  • articular/joint pain/arthralgia
  • acrocyanosis/raynaud's phenomenon/vasomotor disorders
  • chronic skin infection/ulcerations/ulcers/cancrum
  • sensitive trouble/deficit
  • gangrena/necrosis
  • paresthesia/dysesthesia/hypoesthesia/anesthesia/numbness
  • vascularitis/vasculitides/arteritis
  • insomnia
  • hyperhidrosis/increased sweating

Drugs & Therapeutics for Thromboangiitis Obliterans

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 31LifeMap Discovery™, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Thromboangiitis Obliterans

Search NIH Clinical Center for Thromboangiitis Obliterans

Inferred drug relations via UMLS62/NDF-RT41:

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Thromboangiitis Obliterans cell therapies at LifeMap Discovery.

Genetic Tests for Thromboangiitis Obliterans

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Anatomical Context for Thromboangiitis Obliterans

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31LifeMap Discovery™, 33MalaCards
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MalaCards organs/tissues related to Thromboangiitis Obliterans:

33
Bone, Skin, Endothelial, Bone marrow, Colon, Heart, Spinal cord, Kidney

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Thromboangiitis Obliterans:
id TissueAnatomical CompartmentCell Relevance
1 AdiposeSubcutaneous White AdiposeMesenchymal Stem Cells Potential therapeutic candidate
2 AdiposeSubcutaneous White AdiposeStromal Cells Potential therapeutic candidate

Animal Models for Thromboangiitis Obliterans or affiliated genes

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37MGI
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Publications for Thromboangiitis Obliterans

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52PubMed
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Articles related to Thromboangiitis Obliterans:

(show top 50)    (show all 296)
idTitleAuthorsYear
1
Temporal artery involvement as the presenting sign of thromboangiitis obliterans. (23519182)
2013
2
Imbalanced matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 activities in patients with thromboangiitis obliterans. (22402936)
2012
3
Buerger's disease (Thromboangiitis obliterans): a diagnostic challenge. (22679237)
2011
4
Buerger's Disease (Thromboangiitis Obliterans)- Management by Ilizarov's Technique of Horizontal Distraction. A Retrospective Study of 60 Cases. (22211037)
2011
5
Effectiveness of bosentan in the treatment of ischemic lesions in a case of thromboangiitis obliterans (Buerger disease): a case report. (21810389)
2011
6
Protective effect of Shenfu injection on thromboangiitis obliterans model rats. (21982791)
2011
7
Color doppler flows of corkscrew collaterals in Thromboangiitis obliterans (Buerger's disease) using color duplex ultrasonography. (21679855)
2011
8
Classification of corkscrew collaterals in thromboangiitis obliterans (Buerger's disease): relationship between corkscrew type and prevalence of ischemic ulcers. (20534945)
2010
9
Thromboangiitis obliterans and endothelial function. (20584171)
2010
10
Treatment of Buerger disease (thromboangiitis obliterans) with bosentan: a case report. (21686681)
2009
11
Thromboangiitis obliterans in the 21st century--a new face of disease. (19269635)
2009
12
Thromboangiitis obliterans (Buerger disease). (17418073)
2007
13
A prospective, case-control study of tobacco dependence in thromboangiitis obliterans (Buerger's Disease). (16444459)
2006
14
One of the most frequent vascular diseases in northeastern of Turkey: Thromboangiitis obliterans or Buerger's disease (experience with 344 cases). (16580754)
2006
15
Inflammatory joint disease and severe ischemia of the extremities revealing thromboangiitis obliterans in a female. (15681252)
2005
16
Thromboangiitis obliterans associated with peripheral blood and eosinophilic cellulitis-like skin lesions. (15985040)
2005
17
Involvement of the coronary artery in a patient with thromboangiitis obliterans. A case report. (12181595)
2002
18
Distribution of arterial involvement in thromboangiitis obliterans (Buerger's disease): results of a study conducted by the Intractable Vasculitis Syndromes Research Group in Japan. (10930225)
2000
19
Current status of thromboangiitis obliterans (Buerger's disease) in Japan. (10980360)
2000
20
Implantable spinal cord stimulator to treat the ischemic manifestations of thromboangiitis obliterans (Buerger's disease). (10231644)
1999
21
Study of anti-neutrophil cytoplasmic antibodies in patients with thromboangiitis obliterans (Buerger's disease). (9822265)
1998
22
Is the capillary microscopic determination of the visible capillary length a diagnostic criterion in thromboangiitis obliterans? (9612111)
1998
23
Inpatient treatment of severe nicotine dependence in a patient with thromboangiitis obliterans (Buerger's disease). (9621859)
1998
24
Thromboangiitis obliterans (Buerger's disease) in visceral vessels confirmed by angiographic and histological findings. (9854560)
1998
25
Thromboangiitis obliterans (Buerger's disease). (9189999)
1997
26
Pharmacokinetics and tolerability of oral iloprost in thromboangiitis obliterans patients. (9349930)
1997
27
Thromboangiitis obliterans with arthralgia, diarrhea and nodules as the first symptoms. (9190014)
1997
28
Thromboangiitis obliterans (Buerger's disease) (9119522)
1996
29
Case of thromboangiitis obliterans (Buerger's disease) of the upper lip. (7573750)
1995
30
Impotence as a cardinal sign in the thromboangiitis obliterans diagnosis. (8608695)
1995
31
Cerebral thromboangiitis obliterans: clinical and MRI findings in a case. (7671993)
1995
32
Thromboangiitis obliterans. (7518238)
1994
33
Buerger's disease (thromboangiitis obliterans). (2189162)
1990
34
Serum zinc and copper in patients with atherosclerosis and thromboangiitis obliterans. (2484753)
1989
35
CAT scan and immunohistochemical findings in a case of cerebral thromboangiitis obliterans (Buerger's disease). (6714279)
1984
36
Cellular sensitivity to collagen in thromboangiitis obliterans. (6835334)
1983
37
Buerger's disease (thromboangiitis obliterans): an analysis of the arteriograms of 119 cases. (7067357)
1982
38
Autoantibodies in thromboangiitis obliterans (Buerger's disease). (6751163)
1982
39
Factors influenced on prognosis of reconstructive surgery for peripheral arterial occlusion: comparative study between arteriosclerosis obliterans and thromboangiitis obliterans. (599159)
1977
40
Traditional chinese medicine in the treatment of thromboangiitis obliterans. Report of 136 cases. (5678364)
1968
41
Coexistence of thromboangiitis obliterans and arteriosclerosis: relationship to smoking. (5914684)
1966
42
Thromboangiitis obliterans and arteriosclerosis obliterans. (5833515)
1965
43
THROMBOANGIITIS OBLITERANS AND ARTERIOSCLEROSIS OBLITERANS. CLINICAL AND PROGNOSTIC DIFFERENCES. (14065946)
1963
44
Cogan's syndrome and systemic vascular disease. Analysis of pathologic features with reference to its relationship to thromboangiitis obliterans (Buerger). (13893233)
1961
45
Cerebral thromboangiitis obliterans. Neuropathologic aspects. (14489385)
1961
46
Thromboangiitis obliterans: a 30-year study. (13502019)
1958
47
Thromboangiitis obliterans in two brothers. (14952874)
1952
48
A follow-up study of patient with thromboangiitis obliterans (Buerger's disease). (15395864)
1949
49
Cerebral thromboangiitis obliterans. (20289123)
1947
50
Treatment of thromboangiitis obliterans. (21006071)
1945

Variations for Thromboangiitis Obliterans

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Expression for genes affiliated with Thromboangiitis Obliterans

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Thromboangiitis Obliterans

Search GEO for disease gene expression data for Thromboangiitis Obliterans.

Pathways for genes affiliated with Thromboangiitis Obliterans

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Sources:
50PathCards, 60Thomson Reuters, 55Reactome, 38NCBI BioSystems Database, 53QIAGEN, 5Cell Signaling Technology, 30KEGG, 54R&D Systems, 12EMD Millipore
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Pathways related to Thromboangiitis Obliterans according to GeneCards/GeneDecks:

(show all 27)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8EDN1, TIMP1
29.7EDN1, NOS3
39.7VCAM1, ICAM1
49.7VCAM1, ICAM1
59.7MMP9, SELE
69.5MMP9, NOS3
79.5MMP9, NOS3
8
Show member pathways
Angiogenesis38
9.5NOS3, MMP9
99.4VCAM1, ICAM1, SELE
109.4SELE, VCAM1, ICAM1
119.4VCAM1, ICAM1, SELE
129.3MMP9, PLAT
139.2NOS3, MMP9, TIMP1
149.2ICAM1, MMP9, VCAM1
159.0SERPINE1, PLAT
16
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades60
9.0NOS3, ICAM1, VCAM1, SELE
179.0VCAM1, NOS3, SELE, ICAM1
18
Show member pathways
Cytoskeleton remodeling FAK signaling60
Development Endothelin 1 EDNRA transactivation of EGFR60
8.9MMP9, NOS3, HTR2A, EDN1
198.9ICAM1, PLAT, MMP9
208.9SERPINE1, VCAM1, ICAM1
21
Show member pathways
thioredoxin pathway38
8.6PLAT, SERPINE1, ICAM1
228.5NOS3, EDN1, TIMP1, SERPINE1
238.5MMP9, SELE, ICAM1, EDN1, VCAM1
24
Show member pathways
8.3SERPINE1, ICAM1, VCAM1, MMP9
25
Show member pathways
8.2MMP9, SERPINE1, PLAT, TIMP1
26
Show member pathways
8.0ICAM1, MMP9, VCAM1, SERPINE1, TIMP1
27
Show member pathways
8.0TIMP1, SERPINE1, NOS3, SELE, PLAT

Compounds for genes affiliated with Thromboangiitis Obliterans

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Sources:
45Novoseek, 51PharmGKB, 29IUPHAR, 11DrugBank, 61Tocris Bioscience, 24HMDB, 3BitterDB
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Compounds related to Thromboangiitis Obliterans according to GeneCards/GeneDecks:

(show top 50)    (show all 213)
idCompoundScoreTop Affiliating Genes
1carvedilol45 51 29 1112.3VCAM1, EDN1, SELE, NOS3
2gliclazide45 51 1111.1PLAT, SELE, VCAM1, ICAM1
3iloprost61 29 45 1112.1PLAT, VCAM1, SELE, EDN1
4apocynin45 6110.0VCAM1, SELE, EDN1, ICAM1, NOS3
5polymyxin b458.9ICAM1, SERPINE1, SELE, VCAM1
6l-nmma458.8NOS3, EDN1, VCAM1, MMP9
7cytochalasin d45 619.8SELE, VCAM1, MMP9, ICAM1, TIMP1
8nebivolol45 119.8NOS3, SERPINE1, EDN1
9quinapril45 51 1110.7EDN1, SERPINE1, SELE, PLAT
10folate458.7NOS3, TIMP1, MMP9, VCAM1, SELE, APOH
11norepinephrine45 24 1110.7SELE, HTR2A, MMP9, VCAM1, TIMP1, EDN1
12hirudin458.6PLAT, SELE, SERPINE1, TIMP1
13herbimycin a45 619.6MMP9, SELE, TIMP1, ICAM1, VCAM1, EDN1
14ciglitazone45 299.5SERPINE1, MMP9, ICAM1, NOS3
15endotoxin458.5ICAM1, APOH, SERPINE1, SELE, VCAM1
16pravastatin45 51 29 24 1112.5NOS3, ICAM1, VCAM1, SELE, SERPINE1
17nifedipine45 29 51 1111.4TIMP1, MMP9, SELE, SERPINE1, EDN1
18histamine45 29 2410.4PLAT, VCAM1, EDN1, TIMP1, SELE, ICAM1
19losartan45 51 29 1111.4PLAT, VCAM1, SERPINE1, SELE, EDN1
20pge2458.3VCAM1, EDN1, TIMP1, SELE, MMP9, ICAM1
21lactate458.3TIMP1, APOH, ICAM1, SELE, VCAM1, MMP9
22sodium nitroprusside458.2VCAM1, PLAT, NOS3, SERPINE1, EDN1
23methotrexate51 45 1110.2TIMP1, APOH, MMP9, SELE, NOS3, SERPINE1
24cyclophosphamide45 51 1110.2APOH, NOS3, MMP9, VCAM1, SELE, SERPINE1
25rosiglitazone29 45 51 24 1112.2SELE, NOS3, MMP9, VCAM1, SERPINE1, TIMP1
26isoproterenol45 119.2SERPINE1, PLAT, SELE, EDN1, VCAM1
27homocysteine45 249.1APOH, VCAM1, PLAT, NOS3, SERPINE1, SELE
28aspirin45 51 29 2411.1SELE, NOS3, SERPINE1, TIMP1, APOH, PLAT
29fenofibrate45 51 1110.1SERPINE1, NOS3, SELE, VCAM1, MMP9, ICAM1
30phosphatidylinositol458.0MMP9, VCAM1, TIMP1, APOH, NOS3, EDN1
31nicotine45 29 51 1110.9SERPINE1, SELE, MMP9, ICAM1, PLAT
32troglitazone45 29 61 1110.8MMP9, VCAM1, SELE, PLAT, ICAM1, SERPINE1
33ly294002457.7MMP9, SELE, TIMP1, VCAM1, NOS3, ICAM1
34heparin45 29 24 1110.6APOH, SELE, PLAT, VCAM1, SERPINB1, TIMP1
35pd 98,059457.6VCAM1, SERPINE1, TIMP1, EDN1, ICAM1, NOS3
36nitric oxide45 24 119.6APOH, EDN1, ICAM1, TIMP1, SERPINE1, SELE
37fibrinogen457.6SELE, VCAM1, SERPINE1, ICAM1, PLAT, APOH
38aspartate457.5TIMP1, PLAT, VCAM1, SELE, SERPINE1, MMP9
39fluvastatin45 51 29 1110.5SELE, NOS3, VCAM1, MMP9, ICAM1, PLAT
40simvastatin45 51 61 29 24 1112.4SELE, PLAT, MMP9, ICAM1, VCAM1, SERPINE1
418-isoprostane457.4EDN1, VCAM1, NOS3, SELE, SERPINE1, MMP9
42cycloheximide457.4SERPINE1, SELE, PLAT, ICAM1, EDN1, TIMP1
43sb 20358045 618.4EDN1, SELE, VCAM1, MMP9, ICAM1, NOS3
44genistein45 29 61 3 24 1112.4MMP9, ICAM1, VCAM1, SELE, SERPINE1, TIMP1
45creatinine457.3SELE, EDN1, APOH, PLAT, MMP9, SERPINE1
46matrigel457.1SERPINE1, TIMP1, VCAM1, SELE, NOS3, MMP9
47vegf457.1TIMP1, APOH, SERPINE1, MMP9, SELE, NOS3
48actinomycin d457.1SELE, MMP9, EDN1, NOS3, TIMP1, ICAM1
49prostacyclin457.0ICAM1, VCAM1, SELE, SERPINE1, TIMP1, APOH
50atorvastatin45 51 29 24 1110.8TIMP1, SERPINE1, SELE, NOS3, PLAT, ICAM1

GO Terms for genes affiliated with Thromboangiitis Obliterans

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16Gene Ontology
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Cellular components related to Thromboangiitis Obliterans according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1caveolaGO:0059019.4HTR2A, SELE, NOS3
2extracellular matrixGO:0310128.5PLAT, SERPINE1, APOH
3extracellular regionGO:0055767.8EDN1, TIMP1, SERPINE1, MMP9, PLAT
4extracellular spaceGO:0056156.2SELE, APOH, SERPINE1, SERPINB1, VCAM1, MMP9

Biological processes related to Thromboangiitis Obliterans according to GeneCards/GeneDecks:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of smooth muscle cell apoptotic processGO:03439210.2APOH, EDN1
2artery smooth muscle contractionGO:01482410.1HTR2A, EDN1
3leukocyte tethering or rollingGO:05090110.1SELE, VCAM1
4regulation of systemic arterial blood pressure by endothelinGO:00310010.1NOS3, EDN1
5negative regulation of potassium ion transportGO:04326710.1HTR2A, NOS3
6membrane to membrane dockingGO:02261410.0ICAM1, VCAM1
7phosphatidylinositol 3-kinase signalingGO:01406510.0HTR2A, EDN1
8plasminogen activationGO:0316399.9APOH, PLAT
9negative regulation of calcium ion transportGO:0519269.9ICAM1, NOS3
10positive regulation of vasoconstrictionGO:0459079.9HTR2A, ICAM1
11agingGO:0075689.8TIMP1, VCAM1, HTR2A
12response to nicotineGO:0350949.8EDN1, VCAM1
13leukocyte cell-cell adhesionGO:0071599.8SELE, VCAM1, ICAM1
14heterophilic cell-cell adhesionGO:0071579.8ICAM1, VCAM1, SELE
15response to amino acidGO:0432009.7EDN1, ICAM1
16response to lipopolysaccharideGO:0324969.7VCAM1, SELE, EDN1
17negative regulation of fibrinolysisGO:0519189.7SERPINE1, APOH
18cellular response to glucose stimulusGO:0713339.7ICAM1, VCAM1
19cellular response to tumor necrosis factorGO:0713569.7EDN1, VCAM1, ICAM1
20positive regulation of blood coagulationGO:0301949.6APOH, SERPINE1
21positive regulation of nitric oxide biosynthetic processGO:0454299.5ICAM1, EDN1
22leukocyte migrationGO:0509009.5ICAM1, MMP9, SELE
23negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020429.4NOS3, SERPINE1
24negative regulation of blood coagulationGO:0301959.4SERPINE1, APOH, EDN1
25response to hypoxiaGO:0016669.4PLAT, VCAM1, EDN1
26cellular response to interleukin-1GO:0713479.3ICAM1, EDN1
27fibrinolysisGO:0427309.2SERPINE1, PLAT
28negative regulation of endopeptidase activityGO:0109519.1SERPINB1, SERPINE1, TIMP1
29extracellular matrix organizationGO:0301988.4ICAM1, MMP9, VCAM1, SERPINE1, TIMP1
30blood coagulationGO:0075968.4TIMP1, SERPINE1, SELE, PLAT, NOS3

Molecular functions related to Thromboangiitis Obliterans according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055156.4NOS3, PLAT, ICAM1, MMP9, SELE, SERPINE1

Products for genes affiliated with Thromboangiitis Obliterans

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Sources for Thromboangiitis Obliterans

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet