MCID: THR100
MIFTS: 35

Thrombocytopenic Purpura, Autoimmune malady

Rare diseases, Immune diseases, Blood diseases categories

Aliases & Classifications for Thrombocytopenic Purpura, Autoimmune

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Sources:
46OMIM, 8Disease Ontology, 9diseasecard, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 48Orphanet, 61UMLS, 39NCIt, 56SNOMED-CT, 33MeSH, 26ICD10 via Orphanet, 62UMLS via Orphanet, 34MESH via Orphanet, 25ICD10
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Aliases & Descriptions for Thrombocytopenic Purpura, Autoimmune:

Name: Thrombocytopenic Purpura, Autoimmune 46 9 42 48
Immune Thrombocytopenic Purpura 8 42 48 61
Autoimmune Thrombocytopenic Purpura 8 42 10
Idiopathic Thrombocytopenic Purpura 8 42
Immune Thrombocytopenia 42 48
Itp 42 48
 
Thrombocytopenia Due to Platelet Alloimmunization 61
Purpura, Thrombocytopenic, Idiopathic 61
Purpura Thrombocytopenic Idiopathic 44
Thrombocytopenic Purpura Autoimmune 42
Primary Thrombocytopenic Purpura 8


Classifications:



Characteristics (Orphanet epidemiological data):

48
thrombocytopenic purpura, autoimmune:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: All ages


External Ids:

OMIM46 188030
Disease Ontology8 DOID:8924
NCIt39 C3446
MeSH33 D016553
Orphanet48 3002
ICD10 via Orphanet26 D69.3
UMLS via Orphanet62 C0398650
MESH via Orphanet34 D016553
ICD1025 D69.3

Summaries for Thrombocytopenic Purpura, Autoimmune

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NIH Rare Diseases:42 Idiopathic thrombocytopenic purpura (itp) is a bleeding disorder characterized by too few platelets in the blood. this is because platelets are being destroyed by the immune system. symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. with treatment, the chance of remission (a symptom-free period) is good. rarely, itp may become a chronic ailment in adults and reappear, even after remission. last updated: 4/22/2011

MalaCards based summary: Thrombocytopenic Purpura, Autoimmune, also known as immune thrombocytopenic purpura, is related to purpura and thrombocytopenia, and has symptoms including autosomal dominant inheritance, thrombocytopenia and abnormal bleeding. An important gene associated with Thrombocytopenic Purpura, Autoimmune is FCGR2C (Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)). The drugs azathioprine and cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and skin.

Disease Ontology:8 A primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies.

OMIM:46 Autoimmune thrombocytopenic purpura is characterized by a low platelet count, normal bone marrow, and the absence of... (188030) more...

Wikipedia:64 Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenia, primary immune... more...

Related Diseases for Thrombocytopenic Purpura, Autoimmune

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Graphical network of the top 20 diseases related to Thrombocytopenic Purpura, Autoimmune:



Diseases related to thrombocytopenic purpura, autoimmune

Symptoms for Thrombocytopenic Purpura, Autoimmune

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Symptoms by clinical synopsis from OMIM:

188030

Clinical features from OMIM:

188030

HPO human phenotypes related to Thrombocytopenic Purpura, Autoimmune:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 thrombocytopenia HP:0001873
3 abnormal bleeding HP:0001892
4 platelet antibody positive HP:0003454

Drugs & Therapeutics for Thrombocytopenic Purpura, Autoimmune

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Drug clinical trials:

Search ClinicalTrials for Thrombocytopenic Purpura, Autoimmune

Search NIH Clinical Center for Thrombocytopenic Purpura, Autoimmune

Inferred drug relations via UMLS61/NDF-RT40:

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Genetic Tests for Thrombocytopenic Purpura, Autoimmune

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Anatomical Context for Thrombocytopenic Purpura, Autoimmune

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MalaCards organs/tissues related to Thrombocytopenic Purpura, Autoimmune:

31
Bone marrow, Bone, Skin

Animal Models for Thrombocytopenic Purpura, Autoimmune or affiliated genes

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Publications for Thrombocytopenic Purpura, Autoimmune

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Articles related to Thrombocytopenic Purpura, Autoimmune:

idTitleAuthorsYear
1
Autoimmune thrombocytopenic purpura, autoimmune hemolytic anemia and gastric cancer appeared in a patient with myasthenia gravis. (16679706)
2006
2
Rituximab for immune cytopenia in adults: idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, and Evans syndrome. (14601692)
2003
3
Eosinophilic fasciitis following idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia and Hashimoto's disease. (10592421)
1999
4
Cartilage hair hypoplasia with thrombocytopenic purpura, autoimmune haemolytic anaemia and cell-mediated immunodeficiency. (3950893)
1986

Variations for Thrombocytopenic Purpura, Autoimmune

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Expression for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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Search GEO for disease gene expression data for Thrombocytopenic Purpura, Autoimmune.

Pathways for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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Compounds for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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GO Terms for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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Sources for Thrombocytopenic Purpura, Autoimmune

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet