MCID: THR100
MIFTS: 35

Thrombocytopenic Purpura, Autoimmune malady

Rare diseases, Immune diseases, Blood diseases categories

Aliases & Classifications for Thrombocytopenic Purpura, Autoimmune

About this section
Sources:
45OMIM, 9Disease Ontology, 10diseasecard, 41NIH Rare Diseases, 11DISEASES, 43Novoseek, 47Orphanet, 60UMLS, 38NCIt, 55SNOMED-CT, 33MeSH, 26ICD10 via Orphanet, 61UMLS via Orphanet, 34MESH via Orphanet, 25ICD10
See all sources

Thrombocytopenic Purpura, Autoimmune, Aliases & Descriptions:

Name: Thrombocytopenic Purpura, Autoimmune 45 10 41 47
Immune Thrombocytopenic Purpura 9 41 47 60
Autoimmune Thrombocytopenic Purpura 9 41 11
Idiopathic Thrombocytopenic Purpura 9 41
Immune Thrombocytopenia 41 47
Itp 41 47
 
Thrombocytopenia Due to Platelet Alloimmunization 60
Purpura, Thrombocytopenic, Idiopathic 60
Purpura Thrombocytopenic Idiopathic 43
Thrombocytopenic Purpura Autoimmune 41
Primary Thrombocytopenic Purpura 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Immune diseases, Blood diseases


Characteristics (Orphanet epidemiological data):

47
thrombocytopenic purpura, autoimmune:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: All ages


External Ids:

OMIM45 188030
Disease Ontology9 DOID:8924
NCIt38 C3446
MeSH33 D016553
Orphanet47 3002
ICD10 via Orphanet26 D69.3
UMLS via Orphanet61 C0398650
MESH via Orphanet34 D016553
ICD1025 D69.3

Summaries for Thrombocytopenic Purpura, Autoimmune

About this section


NIH Rare Diseases:41 Idiopathic thrombocytopenic purpura (itp) is a bleeding disorder characterized by too few platelets in the blood. this is because platelets are being destroyed by the immune system. symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. with treatment, the chance of remission (a symptom-free period) is good. rarely, itp may become a chronic ailment in adults and reappear, even after remission. last updated: 4/22/2011

MalaCards based summary: Thrombocytopenic Purpura, Autoimmune, also known as immune thrombocytopenic purpura, is related to purpura and thrombocytopenia, and has symptoms including autosomal dominant inheritance, thrombocytopenia and abnormal bleeding. An important gene associated with Thrombocytopenic Purpura, Autoimmune is FCGR2C (Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)). The drugs azathioprine and cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and skin.

Disease Ontology:9 A primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies.

OMIM:45 Autoimmune thrombocytopenic purpura is characterized by a low platelet count, normal bone marrow, and the absence of... (188030) more...

Wikipedia:63 Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenia, primary immune... more...

Related Diseases for Thrombocytopenic Purpura, Autoimmune

About this section

Graphical network of the top 20 diseases related to Thrombocytopenic Purpura, Autoimmune:



Diseases related to thrombocytopenic purpura, autoimmune

Symptoms for Thrombocytopenic Purpura, Autoimmune

About this section

Symptoms by clinical synopsis from OMIM:

188030

Clinical features from OMIM:

188030

HPO human phenotypes related to Thrombocytopenic Purpura, Autoimmune:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 thrombocytopenia HP:0001873
3 abnormal bleeding HP:0001892
4 platelet antibody positive HP:0003454

Drugs & Therapeutics for Thrombocytopenic Purpura, Autoimmune

About this section

Drug clinical trials:

Search ClinicalTrials for Thrombocytopenic Purpura, Autoimmune

Search NIH Clinical Center for Thrombocytopenic Purpura, Autoimmune

Inferred drug relations via UMLS60/NDF-RT39:

Show with subtypes

Genetic Tests for Thrombocytopenic Purpura, Autoimmune

About this section

Anatomical Context for Thrombocytopenic Purpura, Autoimmune

About this section

MalaCards organs/tissues related to Thrombocytopenic Purpura, Autoimmune:

31
Bone marrow, Bone, Skin

Animal Models for Thrombocytopenic Purpura, Autoimmune or affiliated genes

About this section

Publications for Thrombocytopenic Purpura, Autoimmune

About this section

Articles related to Thrombocytopenic Purpura, Autoimmune:

idTitleAuthorsYear
1
Autoimmune thrombocytopenic purpura, autoimmune hemolytic anemia and gastric cancer appeared in a patient with myasthenia gravis. (16679706)
2006
2
Rituximab for immune cytopenia in adults: idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, and Evans syndrome. (14601692)
2003
3
Eosinophilic fasciitis following idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia and Hashimoto's disease. (10592421)
1999
4
Cartilage hair hypoplasia with thrombocytopenic purpura, autoimmune haemolytic anaemia and cell-mediated immunodeficiency. (3950893)
1986

Variations for Thrombocytopenic Purpura, Autoimmune

About this section

Expression for genes affiliated with Thrombocytopenic Purpura, Autoimmune

About this section
Search GEO for disease gene expression data for Thrombocytopenic Purpura, Autoimmune.

Pathways for genes affiliated with Thrombocytopenic Purpura, Autoimmune

About this section

Compounds for genes affiliated with Thrombocytopenic Purpura, Autoimmune

About this section

GO Terms for genes affiliated with Thrombocytopenic Purpura, Autoimmune

About this section

Products for genes affiliated with Thrombocytopenic Purpura, Autoimmune

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Thrombocytopenic Purpura, Autoimmune

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet