MCID: THR100
MIFTS: 36

Thrombocytopenic Purpura, Autoimmune malady

Rare diseases, Immune diseases, Blood diseases categories

Summaries for Thrombocytopenic Purpura, Autoimmune

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NIH Rare Diseases:43 Idiopathic thrombocytopenic purpura (itp) is a bleeding disorder characterized by too few platelets in the blood. this is because platelets are being destroyed by the immune system. symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. with treatment, the chance of remission (a symptom-free period) is good. rarely, itp may become a chronic ailment in adults and reappear, even after remission. last updated: 4/22/2011

MalaCards based summary: Thrombocytopenic Purpura, Autoimmune, also known as autoimmune thrombocytopenic purpura, is related to purpura and thrombocytopenia, and has symptoms including autosomal dominant inheritance, thrombocytopenia and abnormal bleeding. An important gene associated with Thrombocytopenic Purpura, Autoimmune is FCGR2C (Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)). Affiliated tissues include bone marrow, bone and skin.

Disease Ontology:10 A primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies.

OMIM:47 Autoimmune thrombocytopenic purpura is characterized by a low platelet count, normal bone marrow, and the absence of... (188030) more...

Wikipedia:65 Idiopathic thrombocytopenic purpura (ITP), also known as immune thrombocytopenia, primary immune... more...

Aliases & Classifications for Thrombocytopenic Purpura, Autoimmune

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Sources:
47OMIM, 11diseasecard, 43NIH Rare Diseases, 49Orphanet, 10Disease Ontology, 12DISEASES, 45Novoseek, 40NCIt, 57SNOMED-CT, 62UMLS, 35MeSH, 28ICD10 via Orphanet, 63UMLS via Orphanet, 36MESH via Orphanet, 27ICD10
See all sources

Thrombocytopenic Purpura, Autoimmune, Aliases & Descriptions:

Name: Thrombocytopenic Purpura, Autoimmune 47 11 43 49
Autoimmune Thrombocytopenic Purpura 10 43 12
Immune Thrombocytopenic Purpura 10 43 49
Idiopathic Thrombocytopenic Purpura 10 43
Immune Thrombocytopenia 43 49
 
Itp 43 49
Purpura Thrombocytopenic Idiopathic 45
Thrombocytopenic Purpura Autoimmune 43
Primary Thrombocytopenic Purpura 10


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Immune diseases, Blood diseases


Characteristics (Orphanet epidemiological data):

49
thrombocytopenic purpura, autoimmune:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: All ages


External Ids:

OMIM47 188030
Disease Ontology10 DOID:8924
NCIt40 C3446
MeSH35 D016553
Orphanet49 3002
ICD10 via Orphanet28 D69.3
UMLS via Orphanet63 C0398650
MESH via Orphanet36 D016553
ICD1027 D69.3

Related Diseases for Thrombocytopenic Purpura, Autoimmune

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Graphical network of the top 20 diseases related to Thrombocytopenic Purpura, Autoimmune:



Diseases related to thrombocytopenic purpura, autoimmune

Symptoms for Thrombocytopenic Purpura, Autoimmune

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Symptoms by clinical synopsis from OMIM:

188030

Clinical features from OMIM:

188030

HPO human phenotypes related to Thrombocytopenic Purpura, Autoimmune:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 thrombocytopenia HP:0001873
3 abnormal bleeding HP:0001892
4 platelet antibody positive HP:0003454

Drugs & Therapeutics for Thrombocytopenic Purpura, Autoimmune

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Drug clinical trials:

Search ClinicalTrials for Thrombocytopenic Purpura, Autoimmune

Search NIH Clinical Center for Thrombocytopenic Purpura, Autoimmune

Genetic Tests for Thrombocytopenic Purpura, Autoimmune

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Anatomical Context for Thrombocytopenic Purpura, Autoimmune

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MalaCards organs/tissues related to Thrombocytopenic Purpura, Autoimmune:

33
Bone marrow, Bone, Skin

Animal Models for Thrombocytopenic Purpura, Autoimmune or affiliated genes

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Publications for Thrombocytopenic Purpura, Autoimmune

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Articles related to Thrombocytopenic Purpura, Autoimmune:

idTitleAuthorsYear
1
Autoimmune thrombocytopenic purpura, autoimmune hemolytic anemia and gastric cancer appeared in a patient with myasthenia gravis. (16679706)
2006
2
Rituximab for immune cytopenia in adults: idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, and Evans syndrome. (14601692)
2003
3
Eosinophilic fasciitis following idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia and Hashimoto's disease. (10592421)
1999
4
Cartilage hair hypoplasia with thrombocytopenic purpura, autoimmune haemolytic anaemia and cell-mediated immunodeficiency. (3950893)
1986

Variations for Thrombocytopenic Purpura, Autoimmune

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Expression for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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Search GEO for disease gene expression data for Thrombocytopenic Purpura, Autoimmune.

Pathways for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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Compounds for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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GO Terms for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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Products for genes affiliated with Thrombocytopenic Purpura, Autoimmune

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Thrombocytopenic Purpura, Autoimmune

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet