MCID: THR015
MIFTS: 59

Thrombophilia malady

Categories: Genetic diseases, Blood diseases, Immune diseases, Rare diseases

Aliases & Classifications for Thrombophilia

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Aliases & Descriptions for Thrombophilia:

Name: Thrombophilia 11 24 27 50 2 39 13 68
 
Hypercoagulability State 11

Classifications:



External Ids:

Disease Ontology11 DOID:2452
ICD1030 D68.59
MeSH39 D019851
NCIt45 C84479

Summaries for Thrombophilia

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CDC:2 Many people who have or have had family members with hemophilia will ask that their baby boys get tested soon after birth.

MalaCards based summary: Thrombophilia, also known as hypercoagulability state, is related to thrombophilia due to activated protein c resistance and budd-chiari syndrome. An important gene associated with Thrombophilia is F5 (Coagulation Factor V), and among its related pathways are AGE-RAGE signaling pathway in diabetic complications and Dissolution of Fibrin Clot. Affiliated tissues include testes, liver and placenta, and related mouse phenotypes are Synthetic lethal with vaccinia virus (VACV) infection and liver/biliary system.

Wikipedia:71 Thrombophilia (sometimes hypercoagulability or a prothrombotic state) is an abnormality of blood... more...

Related Diseases for Thrombophilia

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Diseases in the Thrombophilia family:

Thrombophilia Due to Activated Protein C Resistance Thrombophilia, Familial, Due to Decreased Release of Plat
Thrombophilia Due to Thrombin Defect Thrombophilia Due to Thrombomodulin Defect
Prothrombin-Related Thrombophilia

Diseases related to Thrombophilia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 296)
idRelated DiseaseScoreTop Affiliating Genes
1thrombophilia due to activated protein c resistance33.1APOH, F2, F3, F5, MTHFR, SERPINC1
2budd-chiari syndrome30.3APOH, F2, F3, F5, MTHFR, SERPINC1
3hemolytic-uremic syndrome29.8F2, F3, SERPINC1
4lung cancer29.5APOH, F5, MTHFR
5ischemic optic neuropathy29.3APOH, F2, SERPINC1, SERPINE1, VWF
6essential thrombocythemia28.7F2, F3, F8, F9, SERPINC1, VWF
7myeloproliferative neoplasm28.7F2, F3, F8, SERPINC1, VWF
8myocardial infarction28.1F2, F3, F5, F8, MTHFR, PROCR
9prothrombin-related thrombophilia12.4
10factor v leiden thrombophilia12.2
11thrombophilia due to hrg deficiency12.2
12thrombophilia due to thrombin defect12.2
13thrombophilia due to protein c deficiency, autosomal recessive12.2
14thrombophilia due to antithrombin iii deficiency12.1
15thrombophilia due to protein s deficiency, autosomal recessive12.1
16thrombophilia due to protein s deficiency, autosomal dominant12.1
17thrombophilia due to thrombomodulin defect12.0
18thrombophilia, x-linked, due to factor ix defect12.0
19thrombophilia due to protein c deficiency, autosomal dominant12.0
20thrombophilia due to heparin cofactor ii deficiency12.0
21hereditary thrombophilia due to congenital protein s deficiency11.8
22protein c deficiency11.7
23thrombophilia, familial, due to decreased release of plat11.7
24factor v r2 mutation thrombophilia11.7
25factor vii marburg i variant thrombophilia11.7
26factor v cambridge thrombophilia11.7
27hereditary antithrombin deficiency11.2
28antiphospholipid syndrome11.1
29protein s deficiency11.1
30livedoid vasculopathy11.0
31mthfr thermolabile variant10.7
32thrombosis10.5
33multiple familial trichoepithelioma10.3F5, MTHFR
34congenital insensitivity to pain with severe intellectual disability10.3F2, F5
35med13l syndrome10.3APOH, F5
36scn8a-related epilepsy with encephalopathy10.3F2, MTHFR
37achard thiers syndrome10.3APOH, F5
38photosensitive epilepsy10.3F2, F5, MTHFR
39houlston ironton temple syndrome10.3F2, F5, MTHFR
40myosclerosis, congenital10.3F5, MTHFR, SERPINC1
41villous adenoma10.3F2, F5, MTHFR
42absence of innominate vein10.2F5, MTHFR, SERPINE1
43aminoaciduria10.2F5, MTHFR, SERPINE1
44porphyria10.2F2, MTHFR
45stt3a-cdg and stt3b-cdg10.2F5, SERPINC1, SERPINE1
46neutropenia10.2MTHFR, PROC, SERPINE1
47alpha-2-plasmin inhibitor deficiency10.2F2, MTHFR, SERPINC1
48periosteal chondrosarcoma10.2F2, SERPINC1, SERPINE1
49may-hegglin anomaly10.2APOH, F2, SERPINC1
50cleft lip10.2F5, MTHFR, SERPINC1

Graphical network of the top 20 diseases related to Thrombophilia:



Diseases related to thrombophilia

Symptoms & Phenotypes for Thrombophilia

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GenomeRNAi Phenotypes related to Thrombophilia according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00362-A8.9PROC, SERPINC1, SERPINE1, SERPINF2, THBD

MGI Mouse Phenotypes related to Thrombophilia according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.5F5, F9, PROC, PROS1, SERPINC1, SERPINE1
2MP:00053808.5F2, F3, F5, F9, PROCR, PROS1
3MP:00053877.2F2, F3, F8, F9, PROC, PROCR
4MP:00053857.1F2, F3, F5, F9, PROC, PROCR
5MP:00053976.7F2, F3, F8, F9, PROC, PROCR
6MP:00107685.5APOH, F2, F3, F5, F8, F9
7MP:00053765.1APOH, F2, F3, F5, F8, F9

Drugs & Therapeutics for Thrombophilia

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Drugs for Thrombophilia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 210)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Heparinapproved, investigationalPhase 4, Phase 3, Phase 28489005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Unfractionated heparin
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
2
DalteparinapprovedPhase 4, Phase 33179041-08-1
Synonyms:
Daltepariininatrium
Dalteparin Sodyum
Dalteparin sodium
Dalteparin sodná sůl
Dalteparin-nátrium
Dalteparina sódica
 
Dalteparinnatrium
Dalteparino natrio druska
Dalteparinum Natricum
Dalteparyna sodowa
Daltéparine sodique
Heparin Fragment KABI 2165
Tedelparin
3
Aspirinapproved, vet_approvedPhase 4, Phase 3115250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalicylsäure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide acetylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
Entericin
Enterophen
 
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
acide 2-(acétyloxy)benzoïque
acide acétylsalicylique
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
salicylic acid acetate
ácido acetilsalicílico
4
IronapprovedPhase 411657439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
5
BenzocaineapprovedPhase 4, Phase 320161994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
6
RivaroxabanapprovedPhase 4, Phase 3259366789-02-8
Synonyms:
 
Xarelto
bay 59-7939
7tannic acidapproved, NutraceuticalPhase 4, Phase 32016
8
Cholineapproved, nutraceuticalPhase 415462-49-7305
Synonyms:
(2-Hydroxyethyl)trimethyl ammonium
(2-Hydroxyethyl)trimethylammonium
(beta-hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethyl-ethanaminium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Biocolina
Biocoline
Choline
Choline cation
 
Choline ion
Cholinum
Hepacholine
Hormocline
Lipotril
N,N,N-Trimethylethanol-ammonium
N,N,N-Trimethylethanolammonium
N,N,N-trimethylethanol-ammonium
N-trimethylethanolamine
Neocolina
Paresan
trimethylethanolamine
9AntithrombinsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 1697
10Factor Xa InhibitorsPhase 4, Phase 3411
11Antithrombin IIIPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 1690
12Antibodies, AntiphospholipidPhase 429
13AntibodiesPhase 4, Phase 3, Phase 2, Phase 16394
14AnticoagulantsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 12623
15HIV Protease InhibitorsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 15470
16ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 16394
17Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 223689
18CoagulantsPhase 4, Phase 3, Phase 2, Phase 11500
19Serine Proteinase InhibitorsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 1878
20ThrombinPhase 4, Phase 2, Phase 3, Early Phase 1304
21
protease inhibitorsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 15471
Synonyms:
 
protease inhibitors
22Factor VIIIPhase 4, Phase 3, Phase 1, Phase 2316
23Platelet Aggregation InhibitorsPhase 4, Phase 3, Phase 2, Phase 12516
24Trace ElementsPhase 4, Phase 36001
25Calcium, DietaryPhase 4, Phase 35713
26Heparin, Low-Molecular-WeightPhase 4, Phase 3334
27Fibrinolytic AgentsPhase 4, Phase 3, Phase 22388
28calcium heparinPhase 4, Phase 3, Phase 2848
29AnalgesicsPhase 4, Phase 3, Phase 211733
30MicronutrientsPhase 4, Phase 36001
31Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 34443
32AntipyreticsPhase 4, Phase 31605
33Analgesics, Non-NarcoticPhase 4, Phase 36501
34Antirheumatic AgentsPhase 4, Phase 3, Phase 2, Phase 110956
35Anti-Inflammatory AgentsPhase 4, Phase 310729
36Cyclooxygenase InhibitorsPhase 4, Phase 32870
37Anti-Infective AgentsPhase 4, Phase 3, Early Phase 122062
38LactoferrinPhase 451
39Protein CPhase 4, Phase 2, Phase 3118
40Cytidine Diphosphate CholinePhase 430
41Nootropic AgentsPhase 4716
42serineNutraceuticalPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 1954
43Iron SupplementNutraceuticalPhase 4180
44
TicagrelorapprovedPhase 3, Phase 2316274693-27-59871419
Synonyms:
(1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-D)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
AZD 6140
 
AZD-6140
AZD6140
Brilinta
45
PhenprocoumonapprovedPhase 332435-97-29908, 54680692
Synonyms:
2-hydroxy-3-(1-phenylpropyl)chromen-4-one
3-(1'-Phenyl-propyl)-4-oxycoumarin
3-(1'-Phenyl-propyl)-4-oxycoumarin [German]
3-(1-Phenylpropyl)-4-hydroxycoumarin
3-(alpha-Ethylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenylpropyl)-4-hydroxycoumarin
4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one
435-97-2
AC1L1U3E
AKOS002126557
BRN 1291115
CHEBI:117471
CHEBI:50438
CHEMBL1465
CHEMBL16694
CID9908
D010644
D05457
DB00946
EINECS 207-108-9
Falithiom
Falithrom
Fencumar
Fenprocoumona
Fenprocoumona [INN-Spanish]
Fenprocumon
Fenprocumone
Fenprocumone [DCIT]
 
HSDB 3248
Hexal Brand of Phenprocoumon
LS-55203
Liquamar
Liquamar (TN)
Marcoumar
Marcumar
Marcuphen
MolPort-005-935-554
Oprea1_002598
PHENPROCOUMON
Phenprocoumalol
Phenprocoumarol
Phenprocoumarole
Phenprocoumon (USAN/INN)
Phenprocoumon [USAN:INN:BAN]
Phenprocoumone
Phenprocoumone [INN-French]
Phenprocoumonum
Phenprocoumonum [INN-Latin]
Phenprocumone
Phenprocumonum
Phenprogramma
Phenylpropylhydroxycumarinum
Ro 1-4849
Roche Brand of Phenprocoumon
S2188_Selleck
U29342
UNII-Q08SIO485D
Worwag Brand of Phenprocoumon
fenprocumon
46
rituximabapprovedPhase 3, Phase 2, Phase 11692174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
47
TiclopidineapprovedPhase 3, Phase 247155142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
48
Prednisoneapproved, vet_approvedPhase 3, Phase 2139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
49
WarfarinapprovedPhase 3, Phase 247081-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
50NadroparinapprovedPhase 3359041-08-1

Interventional clinical trials:

(show top 50)    (show all 220)
idNameStatusNCT IDPhase
1Low Molecular Weight Heparin in Prevention of Recurrent Arteriovenous Graft Thrombosis in Chronic Hemodialysis Patients.Unknown statusNCT01970280Phase 4
2Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated PregnanciesCompletedNCT01221844Phase 4
3The Effect of Heparin in Treatment IVF-ET FailureCompletedNCT01214772Phase 4
4Efficacy and Safety of DLBS1033 in Subjects With Type 2 Diabetes MellitusCompletedNCT01865474Phase 4
5Guilford Genomic Medicine Initiative (GGMI)CompletedNCT01372553Phase 4
6Implantation Failure and PGDCompletedNCT00547781Phase 4
7Investigation of Coagulation Parameters in Hereditary Haemorrhagic TelangiectasiaCompletedNCT00230659Phase 4
8Coagulation Profile in Patients Undergoing Video Assisted Thorascopic Surgery (VATS) for Lung CancerCompletedNCT01741506Phase 4
9Clinical Pharmacokinetics Study of ART-123 in Disseminated Intravascular Coagulation (DIC) Subjects With Renal ImpairmentCompletedNCT01704001Phase 4
10Retrospective Study to Capture Dosing and Treatment Outcome Data in Subjects With Severe Congenital Protein C Deficiency Who Were Treated With Protein C Concentrate Under an Emergency Use INDCompletedNCT00161720Phase 4
11Diagnosis and Treatment Strategy of Recurrent Spontaneous Abortion Associated With ThrombophillaRecruitingNCT02986594Phase 4
12Rivaroxaban for Antiphospholipid Antibody SyndromeRecruitingNCT02116036Phase 4
13Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)RecruitingNCT03046693Phase 4
14Safety Study of Alphanate in Previously Treated Patients With Severe Hemophilia ARecruitingNCT00323856Phase 4
15Atenativ Effect on Uterine Blood Flow and PreeclampsiaRecruitingNCT02278575Phase 4
16Aspirin and Enoxaparin for VTE in TraumaActive, not recruitingNCT02396732Phase 4
17Response of Recombinant Antithrombin in Heparin Resistant Patients Undergoing Cardiac SurgeryTerminatedNCT01547728Phase 4
18LMWH to Prevent Preeclampsia and Fetal Growth RestrictionTerminatedNCT00260520Phase 4
19Prophylactic Plasma Infusion Therapy for Congenital Thrombotic Thrombocytopenic PurpuraWithdrawnNCT01754545Phase 4
20Heparin for Pregnant Women With ThrombophiliaUnknown statusNCT01019655Phase 3
21ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft SurgeryUnknown statusNCT01046942Phase 3
22Safety and Efficacy of Low-Dose Ticagrelor in Chinese Patients With NSTE-ACSUnknown statusNCT02415803Phase 3
23Effects of the Concentrated Extract of Soy on Coagulation Factors After MenopauseUnknown statusNCT00925639Phase 3
24D-Dimer Guided Oral Anticoagulant Treatment (OAT)Unknown statusNCT00895505Phase 3
25TIPPS: Thrombophilia in Pregnancy Prophylaxis StudyCompletedNCT00967382Phase 3
26Biomarker Sub Study of the Compression Stockings to Prevent the Post-Thrombotic Syndrome (SOX) TrialCompletedNCT01615705Phase 3
27Low Weight Heparin prOphylaxis for Placental‐Mediated Complications of PrEgnancyCompletedNCT01388322Phase 3
28Low Molecular Weight Heparin and/or Aspirin in Prevention of Habitual AbortionCompletedNCT00959621Phase 3
29Vitamins C and Vitamin E and Cardiovascular RiskCompletedNCT00362518Phase 3
30An Open-label Study of KW-3357CompletedNCT01384903Phase 3
31A Clinical Study of KW-3357 in Patients With DICCompletedNCT01384396Phase 3
32Prevention of Maternal and Perinatal Complications by Enoxaparin in Women With Previous Severe PreeclampsiaCompletedNCT00986765Phase 3
33Study of Recombinant Factor IX Product, IB1001, in Previously Treated Pediatric Subjects With Hemophilia BCompletedNCT01271868Phase 3
34N-Acetylcysteine in Patients With Sickle Cell DiseaseCompletedNCT01849016Phase 3
35Efficacy and Safety Study of Protein C Concentrate in Subjects With Severe Congenital Protein C DeficiencyCompletedNCT00157118Phase 2, Phase 3
36Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or DeliveryCompletedNCT00110513Phase 3
37Study of Recombinant Factor IX Product, IB1001, in Subjects With Hemophilia BCompletedNCT00768287Phase 2, Phase 3
38Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations.CompletedNCT00056550Phase 3
39Xarelto Versus no Treatment for the Prevention of Recurrent Thrombosis in Patients With Chronic Portal Vein Thrombosis.RecruitingNCT02555111Phase 3
40Effects of Different Doses of Ticagrelor on Platelet Aggregation and Endothelial Function in Diabetic Patients With Stable Coronary Artery DiseaseRecruitingNCT02889549Phase 2, Phase 3
41A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge PatientsRecruitingNCT02111564Phase 3
42Safety, Pharmacokinetics and Efficacy of an AT-III Concentrate.RecruitingNCT00319228Phase 2, Phase 3
43Assess the Efficacy and Safety of Personalized Prophylaxis Human-cl rhFVIII in Patients With Severe Haemophilia ARecruitingNCT02256917Phase 3
44Follow-up Study for Patients Who Completed Study ALX0681-C301 (Post-HERCULES)RecruitingNCT02878603Phase 3
45Phase III Trial With Caplacizumab in Patients With Acquired Thrombotic Thrombocytopenic PurpuraRecruitingNCT02553317Phase 3
46Study of Cyclosporine or Corticosteroids as an Adjunct to Plasma Exchange in Thrombotic Thrombocytopenic Purpura (TTP)Active, not recruitingNCT00713193Phase 3
47Hydroxychloroquine for Prevention of Recurrent Miscarriage.Not yet recruitingNCT03165136Phase 3
48Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular CoagulationNot yet recruitingNCT02654561Phase 3
49Prevention of Unexplained Recurrent Abortion by EnoxaparineTerminatedNCT00740545Phase 3
50Weight Adjusted Low Molecular Weight Heparin in Recurrent Implantation Failure: a Randomized Open Labeled TrialTerminatedNCT02991950Phase 3

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Cochrane evidence based reviews: thrombophilia

Genetic Tests for Thrombophilia

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Genetic tests related to Thrombophilia:

id Genetic test Affiliating Genes
1 Thrombophilia27 24

Anatomical Context for Thrombophilia

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MalaCards organs/tissues related to Thrombophilia:

36
Testes, Liver, Placenta, Endothelial, Kidney, Bone, Heart

Publications for Thrombophilia

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Articles related to Thrombophilia:

(show top 50)    (show all 1001)
idTitleAuthorsYear
1
Impact of thrombophilia screening on venous thromboembolism management practices. (27931012)
2017
2
Whole Exome Sequencing Reveals Severe Thrombophilia in Acute Unprovoked Idiopathic Fatal Pulmonary Embolism. (28174134)
2017
3
Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation. (28057640)
2017
4
Thrombophilia Screening. (28049358)
2017
5
Non-vitamin K antagonist oral anticoagulants in patients with severe inherited thrombophilia: a series of 33 patients. (28079536)
2017
6
Cardiovascular risk factors in women with inheritable thrombophilia a decade after single or recurrent hypertensive disorder of pregnancy. (27322349)
2016
7
A Rare Case of Acute Myeloid Leukemia with a t(2;3) Chromosomal Translocation Characterized by Thrombophilia and Chemoresistance. (27334861)
2016
8
Efficacy of dabigatran versus warfarin in patients with acute venous thromboembolism in the presence of thrombophilia: Findings from RE-COVERAr, RE-COVERa8c II, and RE-MEDYa8c. (27807306)
2016
9
Thrombophilia testing results in patients with a first venous thromboembolic event - should the selection criteria for testing be revisited? (27096232)
2016
10
Thrombophilia after total gastrectomy for morbid obesity. (26911993)
2016
11
A case-based reasoning view of thrombophilia risk. (27404848)
2016
12
Congenital limb deficiencies with vascular etiology: Possible association with maternal thrombophilia. (27530094)
2016
13
Analysis of Thrombophilia Test Ordering Practices at an Academic Center: A Proposal for Appropriate Testing to Reduce Harm and Cost. (27176603)
2016
14
Thrombophilia prevalence among women with placenta-mediated pregnancy complications. (27113416)
2016
15
Re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of early-onset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results LMWH influencing fetal growth. (27149359)
2016
16
Hereditary risk factors of thrombophilia and probability of venous thromboembolism during pregnancy and the puerperium. (27613196)
2016
17
Re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of early-onset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results LMWH influencing fetal growth. (27149356)
2016
18
Impact of high risk thrombophilia status on recurrence among children and adults with VTE: An observational multicenter cohort study. (27838551)
2016
19
Authors' reply re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of early-onset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results. (27149358)
2016
20
Protection From Pregnancy Loss in Women With Hereditary Thrombophilia When Associated With Fibrinogen Polymorphism Thr331Ala. (27099386)
2016
21
Thrombophilia and assisted reproduction technology-any detrimental impact or unnecessary overuse? (27423663)
2016
22
Retinal vascular occlusion: a window to diagnosis of familial and acquired thrombophilia and hypofibrinolysis, with important ramifications for pregnancy outcomes. (27563233)
2016
23
The Impact of Inherited Thrombophilia Types and Low Molecular Weight Heparin Treatment on Pregnancy Complications in Women with Previous Adverse Outcome. (27401656)
2016
24
Hospitalization for pulmonary embolism associated with antecedent testosterone or estrogen therapy in patients found to have familial and acquired thrombophilia. (26958344)
2016
25
Asynchronous Bilateral Renal Infarction and Thrombophilia With Associated Gene Mutations in a 43-Year-Old Man: A Case Report. (27057875)
2016
26
Severe Asthma with Joint Pain, Thrombophilia, and Irritable Bowel Syndrome. (27587324)
2016
27
Management of inherited thrombophilia in pregnancy. (27638899)
2016
28
Bilateral Legg-Calve-Perthes Disease and Kienbock's Disease in a Child With Factor V Leiden Thrombophilia: A Case Report. (27698645)
2016
29
Authors' reply re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of earlyonset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results. (27149357)
2016
30
Inpatient inherited thrombophilia testing. (27782379)
2016
31
Genetic susceptibility to deep venous thromboembolism: the roles of inherited thrombophilia polymorphisms. (27023879)
2016
32
Direct Oral Anticoagulants in Patients with Thrombophilia: Challenges in Diagnostic Evaluation and Treatment. (28028988)
2016
33
Inherited thrombophilia in women with poor aPL-related obstetric history: prevalence and outcomes. Survey of 208A cases from the European Registry on Obstetric Antiphospholipid Syndrome cohort. (27401589)
2016
34
Fatal Pulmonary Embolism Due to Inherited Thrombophilia Factors in a Child With Wolfram Syndrome. (27379531)
2016
35
A meta-analysis of low-molecular-weight heparin to prevent pregnancy loss in women with inherited thrombophilia. (26837697)
2016
36
Hereditary Thrombophilia and Recurrent Pregnancy Loss. (27427827)
2016
37
The Prevalence of Thrombophilia in Women With Recurrent Fetal Loss and Outcome of Anticoagulation Therapy for the Prevention of Miscarriages. (27799457)
2016
38
Exome Sequencing and Clot Lysis Experiments Demonstrate the R458C Mutation of the Alpha Chain of Fibrinogen to be Associated with Impaired Fibrinolysis in a Family with Thrombophilia. (26581183)
2016
39
Coagulation, thrombophilia and patency of arteriovenous fistula in children undergoing haemodialysis compared with healthy volunteers: a prospective analysis. (26829282)
2016
40
Inherited thrombophilia: a double-edged sword. (27913455)
2016
41
Sickle cell disease: an inherited thrombophilia. (27913540)
2016
42
Thrombus-like small apical fibroma in patient with left ventricular dysfunction and thrombophilia: an unusual presentation. (27906779)
2016
43
Correlation with Platelet Parameters and Genetic Markers of Thrombophilia Panel (Factor II g.20210G>A, Factor V Leiden, MTHFR (C677T, A1298C), PAI-1, I^-Fibrinogen, Factor XIIIA (V34L), Glycoprotein IIIa (L33P)) in Ischemic Strokes. (26951304)
2016
44
Prethrombotic, prothrombotic, thrombophilic states, hypercoagulable state, thrombophilia etc.: semantics should be respected even in medical papers. (27864647)
2016
45
Combined oral contraceptives, thrombophilia and the risk of venous thromboembolism: a systematic review and meta-analysis. (27121914)
2016
46
No evidence for thrombophilia in patients with retinal venous occlusion: a systematic GRADE-based review. (27573507)
2016
47
The contribution of hereditary thrombophilia to increasing the frequency of thrombosis in patients with Ph negative myeloproliferative neoplasms, including the victims from the Chornobyl accident. (28027559)
2016
48
Impact of high-risk thrombophilia status on recurrence among children with a first non-central-venous-catheter-associated VTE: an observational multicentre cohort study. (27329967)
2016
49
Venous Thromboembolism After Knee Arthroscopy in Undiagnosed Familial Thrombophilia. (27459142)
2016
50
LMWH in the prevention of preeclampsia and fetal growth restriction in women without thrombophilia. A systematic review and meta-analysis. (27440387)
2016

Variations for Thrombophilia

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Copy number variations for Thrombophilia from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1151514202230000025600000LossTHBDThrombophilia

Expression for genes affiliated with Thrombophilia

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Search GEO for disease gene expression data for Thrombophilia.

Pathways for genes affiliated with Thrombophilia

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Pathways related to Thrombophilia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6F3, SERPINE1, THBD
29.5HRG, SERPINE1, SERPINF2
3
Show member pathways
9.4F2, F9, PROC, PROS1
49.4F2, F9, PROC, PROS1
5
Show member pathways
8.6F2, PROC, PROCR, PROS1, THBD
6
Show member pathways
7.6F2, F3, F5, F8, F9, PROC
7
Show member pathways
5.1F2, F3, F5, F8, F9, PROC
8
Show member pathways
5.1F2, F3, F5, F8, F9, PROC
9
Show member pathways
4.4APOH, F2, F3, F5, F8, F9

GO Terms for genes affiliated with Thrombophilia

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Cellular components related to Thrombophilia according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1platelet alpha granuleGO:003109110.2F5, VWF
2Golgi lumenGO:000579610.1F2, F9, PROC, PROS1
3blood microparticleGO:00725629.7F2, HRG, PROS1, SERPINC1, SERPINF2
4extracellular matrixGO:00310129.6APOH, F3, SERPINE1, VWF
5endoplasmic reticulum lumenGO:00057889.0F2, F5, F8, F9, PROC, SERPINC1
6cell surfaceGO:00099868.6APOH, F3, HRG, PROCR, SERPINF2, THBD
7platelet alpha granule lumenGO:00310937.9F5, F8, HRG, PROS1, SERPINE1, SERPINF2
8plasma membraneGO:00058867.0F2, F3, F5, F8, F9, HRG
9extracellular spaceGO:00056156.8APOH, F2, F3, F5, F8, F9
10extracellular exosomeGO:00700626.6APOH, F2, F3, F9, HRG, PROCR
11extracellular regionGO:00055765.5APOH, F2, F3, F5, F8, F9

Biological processes related to Thrombophilia according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of cell adhesion mediated by integrinGO:003362910.7HRG, SERPINE1
2negative regulation of platelet activationGO:001054410.6F2, THBD
3blood coagulation, extrinsic pathwayGO:000759810.5F3, F9
4negative regulation of plasminogen activationGO:001075710.4SERPINE1, SERPINF2
5negative regulation of coagulationGO:005081910.1PROC, PROCR
6positive regulation of blood coagulationGO:003019410.0APOH, F2, SERPINE1
7peptidyl-glutamic acid carboxylationGO:001718710.0F2, F9, PROC, PROS1
8post-translational protein modificationGO:00436879.8F5, PROC, SERPINC1, SERPIND1
9cellular protein metabolic processGO:00442679.8F2, F5, PROC, SERPINC1, SERPIND1
10negative regulation of peptidase activityGO:00104669.7SERPINC1, SERPIND1, SERPINE1, SERPINF2
11acute-phase responseGO:00069539.7F2, F8, SERPINF2
12negative regulation of blood coagulationGO:00301959.7APOH, PROC, PROS1, SERPINE1, THBD
13fibrinolysisGO:00427309.6F2, HRG, PROS1, SERPINE1, SERPINF2
14regulation of blood coagulationGO:00301939.5APOH, F2, HRG, SERPINC1
15signal peptide processingGO:00064659.4F2, F9, PROC, PROS1
16leukocyte migrationGO:00509009.3F2, PROC, PROCR, PROS1, THBD
17negative regulation of endopeptidase activityGO:00109519.3HRG, PROS1, SERPINC1, SERPIND1, SERPINE1, SERPINF2
18ER to Golgi vesicle-mediated transportGO:00068889.2F2, F5, F8, F9, PROC, PROS1
19platelet activationGO:00301689.2F2, F5, F8, HRG, VWF
20negative regulation of fibrinolysisGO:00519189.1APOH, F2, HRG, SERPINE1, SERPINF2, THBD
21blood coagulation, intrinsic pathwayGO:00075979.0APOH, F2, F8, F9, VWF
22platelet degranulationGO:00025768.0APOH, F5, F8, HRG, PROS1, SERPINE1
23blood coagulationGO:00075966.4F2, F3, F5, F8, F9, HRG
24hemostasisGO:00075996.4F2, F3, F5, F8, F9, HRG

Molecular functions related to Thrombophilia according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1immunoglobulin bindingGO:001986510.4HRG, VWF
2endopeptidase inhibitor activityGO:000486610.1PROS1, SERPIND1, SERPINF2
3calcium ion bindingGO:00055099.8F2, F9, PROC, PROS1, THBD
4peptidase inhibitor activityGO:00304149.7SERPINC1, SERPIND1, SERPINE1, SERPINF2
5heparin bindingGO:00082019.5APOH, F2, HRG, SERPINC1, SERPIND1
6protease bindingGO:00020209.1F3, SERPINC1, SERPINE1, SERPINF2, VWF
7serine-type endopeptidase activityGO:00042528.9F2, F3, F5, F8, F9, PROC
8serine-type endopeptidase inhibitor activityGO:00048678.8HRG, SERPINC1, SERPIND1, SERPINE1, SERPINF2

Sources for Thrombophilia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet