MCID: THR053
MIFTS: 15

Thrombophilia, Dysfibrinogenemic malady

Blood diseases category

Summaries for Thrombophilia, Dysfibrinogenemic

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32MalaCards
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MalaCards: Thrombophilia, Dysfibrinogenemic is related to myocardial infarction and afibrinogenemia. An important gene associated with Thrombophilia, Dysfibrinogenemic is FGG (fibrinogen gamma chain), and among its related pathways are Non-integrin membrane-ECM interactions and Cell adhesion ECM remodeling. The compounds fibrinogen and sucralfate have been mentioned in the context of this disorder.

Aliases & Classifications for Thrombophilia, Dysfibrinogenemic

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46OMIM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


Aliases & Descriptions:

thrombophilia, dysfibrinogenemic 46


Related Diseases for Thrombophilia, Dysfibrinogenemic

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17GeneCards, 18GeneDecks
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Diseases related to Thrombophilia, Dysfibrinogenemic via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1myocardial infarction10.0FGB
2afibrinogenemia10.0FGG, FGB

Clinical Features for Thrombophilia, Dysfibrinogenemic

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Drugs & Therapeutics for Thrombophilia, Dysfibrinogenemic

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Thrombophilia, Dysfibrinogenemic

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Anatomical Context for Thrombophilia, Dysfibrinogenemic

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Animal Models for Thrombophilia, Dysfibrinogenemic or affiliated genes

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Publications for Thrombophilia, Dysfibrinogenemic

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Genetic Variations for Thrombophilia, Dysfibrinogenemic

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Expression for genes affiliated with Thrombophilia, Dysfibrinogenemic

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Thrombophilia, Dysfibrinogenemic

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Pathways for genes affiliated with Thrombophilia, Dysfibrinogenemic

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Sources:
53Reactome, 12EMD Millipore, 51QIAGEN, 29KEGG, 37NCBI BioSystems Database, 52R&D Systems, 49PharmGKB
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Compounds for genes affiliated with Thrombophilia, Dysfibrinogenemic

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44Novoseek, 11DrugBank
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Compounds related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1fibrinogen449.1FGG, FGB
2sucralfate44 1110.0FGG, FGB
3rsai448.8FGG, FGB

GO Terms for genes affiliated with Thrombophilia, Dysfibrinogenemic

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16Gene Ontology
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Cellular components related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:0725629.3FGB, FGG
2fibrinogen complexGO:0055779.2FGG, FGB
3platelet alpha granuleGO:0310919.2FGG, FGB
4platelet alpha granule lumenGO:0310939.1FGB, FGG
5cell surfaceGO:0099869.1FGG, FGB
6cell cortexGO:0059389.0FGB, FGG
7external side of plasma membraneGO:0098978.8FGB, FGG

Biological processes related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein polymerizationGO:0512589.2FGB, FGG
2response to calcium ionGO:0515929.1FGB, FGG
3blood coagulationGO:0075969.1FGB, FGG
4platelet degranulationGO:0025769.0FGG, FGB
5platelet activationGO:0301688.8FGG, FGB

Molecular functions related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:0051029.1FGG, FGB
2protein binding, bridgingGO:0306748.8FGG, FGB

Products for genes affiliated with Thrombophilia, Dysfibrinogenemic

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Thrombophilia, Dysfibrinogenemic

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet