MCID: THR053
MIFTS: 11

Thrombophilia, Dysfibrinogenemic malady

Blood category

Summaries for Thrombophilia, Dysfibrinogenemic

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33MalaCards
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MalaCards: Thrombophilia, Dysfibrinogenemic is related to myocardial infarction and afibrinogenemia. An important gene associated with Thrombophilia, Dysfibrinogenemic is FGG (fibrinogen gamma chain), and among its related pathways are Non-integrin membrane-ECM interactions and Cell adhesion ECM remodeling. The compounds fibrinogen and sucralfate have been mentioned in the context of this disorder.

Aliases & Classifications for Thrombophilia, Dysfibrinogenemic

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47OMIM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood


Aliases & Descriptions:

thrombophilia, dysfibrinogenemic 47


Related Diseases for Thrombophilia, Dysfibrinogenemic

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17GeneCards, 18GeneDecks
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Diseases related to Thrombophilia, Dysfibrinogenemic via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1myocardial infarction10.0FGB
2afibrinogenemia10.0FGG, FGB

Clinical Features for Thrombophilia, Dysfibrinogenemic

Drugs & Therapeutics for Thrombophilia, Dysfibrinogenemic

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Thrombophilia, Dysfibrinogenemic

Anatomical Context for Thrombophilia, Dysfibrinogenemic

Animal Models for Thrombophilia, Dysfibrinogenemic or affiliated genes

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28inGenious Targeting Laboratory
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Publications for Thrombophilia, Dysfibrinogenemic

Genetic Variations for Thrombophilia, Dysfibrinogenemic

Expression for genes affiliated with Thrombophilia, Dysfibrinogenemic

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Thrombophilia, Dysfibrinogenemic

Search GEO for disease gene expression data for Thrombophilia, Dysfibrinogenemic.

Pathways for genes affiliated with Thrombophilia, Dysfibrinogenemic

Sources:
54Reactome, 12EMD Millipore, 52QIAGEN, 30KEGG, 38NCBI BioSystems Database, 53R&D Systems, 50PharmGKB
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Compounds for genes affiliated with Thrombophilia, Dysfibrinogenemic

Sources:
45Novoseek, 11DrugBank
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Compounds related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1fibrinogen459.1FGG, FGB
2sucralfate45 1110.0FGG, FGB
3rsai458.8FGG, FGB

GO Terms for genes affiliated with Thrombophilia, Dysfibrinogenemic

Sources:
16Gene Ontology
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Cellular components related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:0725629.3FGG, FGB
2fibrinogen complexGO:0055779.2FGG, FGB
3platelet alpha granuleGO:0310919.2FGG, FGB
4platelet alpha granule lumenGO:0310939.1FGB, FGG
5cell surfaceGO:0099869.1FGG, FGB
6cell cortexGO:0059389.0FGG, FGB
7external side of plasma membraneGO:0098978.8FGG, FGB

Biological processes related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein polymerizationGO:0512589.2FGG, FGB
2response to calcium ionGO:0515929.1FGG, FGB
3blood coagulationGO:0075969.1FGG, FGB
4platelet degranulationGO:0025769.0FGB, FGG
5platelet activationGO:0301688.8FGG, FGB

Molecular functions related to Thrombophilia, Dysfibrinogenemic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:0051029.1FGG, FGB
2protein binding, bridgingGO:0306748.8FGG, FGB

Products for genes affiliated with Thrombophilia, Dysfibrinogenemic

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Thrombophilia, Dysfibrinogenemic

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet