MCID: THR024
MIFTS: 57

Thrombosis malady

Categories: Cardiovascular diseases, Blood diseases

Aliases & Classifications for Thrombosis

Aliases & Descriptions for Thrombosis:

Name: Thrombosis 12 29 52 3 69
Thrombosis of Blood Vessel 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0060903

Summaries for Thrombosis

Disease Ontology : 12 A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.

MalaCards based summary : Thrombosis, also known as thrombosis of blood vessel, is related to budd-chiari syndrome and essential thrombocythemia. An important gene associated with Thrombosis is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Dalteparin and Heparin have been mentioned in the context of this disorder. Affiliated tissues include liver, endothelial and testes, and related phenotypes are homeostasis/metabolism and cardiovascular system

CDC : 3 Many people who have or have had family members with hemophilia will ask that their baby boys get tested soon after birth.

Wikipedia : 71 Thrombosis is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through... more...

Related Diseases for Thrombosis

Diseases related to Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 948)
id Related Disease Score Top Affiliating Genes
1 budd-chiari syndrome 31.3 APOH F2 F3 F5 GP6 MTHFR
2 essential thrombocythemia 31.1 F2 F3 F7 F9 GP1BA SERPINC1
3 thrombophilia due to activated protein c resistance 30.9 APOH F2 F3 F5 F7 JAK2
4 stroke, ischemic 30.2 F2 F3 F5 F7
5 lupus erythematosus 29.9 F3 P2RY12 PLAT SELP SERPINC1 VWF
6 lung cancer 29.7 APOH F5 MTHFR
7 myeloproliferative neoplasm 29.4 F10 F2 F3 GP1BA JAK2 SELP
8 craniopharyngioma 29.3 F3 SERPINE1 THBD
9 influenza 29.2 F2 F3 SERPINC1
10 prostatic hypertrophy 29.2 F2 F3 SELP VWF
11 may-hegglin anomaly 29.2 APOH F2 SERPINC1
12 seminoma 29.2 F2 F3 F7
13 neutropenia 29.2 MTHFR PROC SERPINE1
14 ischemic optic neuropathy 29.1 APOH F2 SELP SERPINC1 SERPINE1 VWF
15 herpes simplex 29.0 APOH THBD VWF
16 central retinal artery occlusion 29.0 APOH F2 F3 MTHFR SERPINC1
17 porphyria 29.0 F2 F7 MTHFR
18 subclavian artery aneurysm 28.9 F10 F3 SELP SERPINE1
19 obstructive jaundice 28.9 APOH F2 F5 MTHFR SERPINC1 THBD
20 pericarditis 28.7 APOH F3 F5 MTHFR PLAT SELP
21 myocardial infarction 28.5 F10 F2 F3 F5 F7 GP1BA
22 portal vein thrombosis 12.3
23 coronary thrombosis 12.2
24 cavernous sinus thrombosis 12.2
25 sagittal sinus thrombosis 12.1
26 intracranial thrombosis 12.0
27 lateral sinus thrombosis 12.0
28 carotid artery thrombosis 12.0
29 cerebral sinovenous thrombosis 12.0
30 intracranial sinus thrombosis 12.0
31 pulmonary hypertension, chronic thromboembolic, without deep vein thrombosis 11.8
32 thrombophilia due to thrombin defect 11.6
33 thrombophilia, x-linked, due to factor ix defect 11.4
34 thrombophilia 11.3
35 heparin-induced thrombocytopenia 11.3
36 factor v leiden thrombophilia 11.3
37 protein s deficiency 11.2
38 dysfibrinogenemia 11.1
39 protein c deficiency 11.1
40 antiphospholipid syndrome 11.1
41 post-thrombotic syndrome 11.1
42 thoracic outlet syndrome 11.1
43 hereditary antithrombin deficiency 11.0
44 pulmonary embolism 11.0
45 venous thoracic outlet syndrome 11.0
46 systemic lupus erythematosus 11.0
47 paroxysmal nocturnal hemoglobinuria 11.0
48 thrombophilia due to thrombomodulin defect 11.0
49 thrombocytosis 11.0
50 ischemia 10.9

Graphical network of the top 20 diseases related to Thrombosis:



Diseases related to Thrombosis

Symptoms & Phenotypes for Thrombosis

MGI Mouse Phenotypes related to Thrombosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.4 PROS1 SELP SERPINC1 SERPINE1 THBD VWF
2 cardiovascular system MP:0005385 10.32 F7 F9 PLAT PROC PROS1 SELP
3 hematopoietic system MP:0005397 10.31 GP6 JAK2 P2RY12 PLAT PROC PROS1
4 immune system MP:0005387 10.15 F2 F3 F9 GP6 JAK2 PLAT
5 mortality/aging MP:0010768 10.11 APOH F10 F2 F3 F5 F7
6 embryo MP:0005380 10.06 F2 F3 F5 F9 JAK2 PROS1
7 integument MP:0010771 10.02 F2 F3 F5 GP6 JAK2 MTHFR
8 liver/biliary system MP:0005370 9.91 PROC PROS1 SELP SERPINC1 SERPINE1 THBD
9 nervous system MP:0003631 9.7 F2 F3 F5 MTHFR PLAT PROC
10 respiratory system MP:0005388 9.17 F2 F3 PLAT PROC SELP SERPINE1

Drugs & Therapeutics for Thrombosis

Drugs for Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 866)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dalteparin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9041-08-1
2
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6 772 46507594
3
Abciximab Approved Phase 4,Phase 3,Phase 2 143653-53-6
4
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
5
Phenobarbital Approved Phase 4 50-06-6 4763
6
Alprostadil Approved, Investigational Phase 4,Phase 3,Phase 2 745-65-3 149351
7
Rivaroxaban Approved Phase 4,Phase 3,Phase 2,Phase 1 366789-02-8
8
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1 1197-18-8 5526
9
Tranylcypromine Approved Phase 4,Phase 3 155-09-9 441233
10
Nicorandil Approved Phase 4 65141-46-0 47528
11
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 274693-27-5 9871419
12
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2 50-28-2 5757 53477783
13
Norethindrone Approved Phase 4 68-22-4 6230
14
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
15
Salicylic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 69-72-7 338
16
Warfarin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 81-81-2 6691 54678486
17
Acenocoumarol Approved Phase 4,Phase 3 152-72-7 9052 54676537
18
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
19
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 73590-58-6 4594
20
Pantoprazole Approved Phase 4,Phase 3,Phase 1 102625-70-7 4679
21
Phenprocoumon Approved Phase 4,Phase 3,Phase 2 435-97-2 9908 54680692
22
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
23
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
24
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128270-60-0 16129704
25
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
26
Tirofiban Approved Phase 4,Phase 3 144494-65-5 60947
27
Nitric Oxide Approved Phase 4,Phase 2,Phase 3,Phase 1 10102-43-9 145068
28
Coal tar Approved Phase 4,Phase 2,Phase 3,Phase 1 8007-45-2
29
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 55-56-1 9552079 2713
30
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2 61825-94-3 5310940 9887054 6857599, 9887054 43805
31
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 188627-80-7 123610
32
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 3 71-58-9
33 Certoparin Approved Phase 4,Phase 3
34
Progesterone Approved, Vet_approved Phase 4,Phase 3 57-83-0 5994
35
Tenecteplase Approved Phase 4,Phase 3,Phase 2,Phase 1 191588-94-0
36 Nadroparin Approved Phase 4,Phase 3,Phase 2 9041-08-1
37
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 216974-75-3
38
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 124-94-7 31307
39
Tinzaparin Approved Phase 4,Phase 3,Phase 2 9005-49-6, 9041-08-1 25244225
40
Argatroban Approved, Investigational Phase 4,Phase 3,Phase 2 74863-84-6 152951
41
Cisplatin Approved Phase 4,Phase 3,Phase 2 15663-27-1 84093 441203 2767
42
Ethiodized oil Approved Phase 4,Phase 3,Phase 2 8008-53-5
43
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
44
Ezetimibe Approved Phase 4 163222-33-1 150311
45
Simvastatin Approved Phase 4,Phase 3,Early Phase 1 79902-63-9 54454
46
Acetylcholine Approved Phase 4,Phase 1 51-84-3 187
47
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 137-58-6 3676
48
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
49
Ranibizumab Approved Phase 4,Phase 2,Phase 3,Phase 1 347396-82-1 459903
50 Edoxaban Approved Phase 4,Phase 3,Phase 2,Phase 1 480449-70-5

Interventional clinical trials:

(show top 50) (show all 3705)
id Name Status NCT ID Phase
1 Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis Unknown status NCT00450645 Phase 4
2 Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis Unknown status NCT01252420 Phase 4
3 Rosuvastatin for Preventing Deep Vein Thrombosis Unknown status NCT01021488 Phase 4
4 Safety and Efficacy Study of OmniWave Endovascular System to Treat Deep Vein Thrombosis Unknown status NCT00640731 Phase 4
5 Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users Unknown status NCT01063426 Phase 4
6 Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Unknown status NCT01383785 Phase 4
7 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Unknown status NCT01245998 Phase 4
8 Hormones Inflammation and Thrombosis Unknown status NCT01875185 Phase 4
9 Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Non-ST-elevation Myocardial Infarction Study Unknown status NCT01013038 Phase 4
10 Hepatic Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Complicated by Portal Vein Tumor Thrombosis Unknown status NCT01350206 Phase 4
11 Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study. Unknown status NCT01914055 Phase 4
12 Antiaggregation in Primary Prevention of Vascular Access for Hemodialysis Unknown status NCT02055131 Phase 4
13 Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery Unknown status NCT00983112 Phase 4
14 Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside) Unknown status NCT00963781 Phase 4
15 Low Molecular Weight Heparin in Prevention of Recurrent Arteriovenous Graft Thrombosis in Chronic Hemodialysis Patients. Unknown status NCT01970280 Phase 4
16 Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction Unknown status NCT01156662 Phase 4
17 Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA Unknown status NCT01670474 Phase 4
18 Randomized Trial of Standard vs ClearWay-infused Abciximab and Thrombectomy for Myocardial Infarction Unknown status NCT01499407 Phase 4
19 The Use of Prostaglandin E1 in Head and Neck Microsurgery Unknown status NCT00733434 Phase 4
20 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4
21 Late Incomplete Stent Apposition Evaluation II: Comparison Between Polimer-based and No-polimer Stent System. IVUS Based Study Unknown status NCT01375855 Phase 4
22 Randomised Controlled Trial of Needle Free Access Devices in Preventing Hemodialysis Blood Stream Infection Unknown status NCT01082770 Phase 4
23 Effectiveness of Blood Clot Medication With Concomitant Blood Pressure Medication Unknown status NCT00424281 Phase 4
24 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4
25 Monitoring Response to Antiplatelet Therapy Unknown status NCT00327041 Phase 4
26 Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy Unknown status NCT02264743 Phase 4
27 Cost Effectiveness Analysis In Patients With Heart Valve Prosthesis Unknown status NCT02022527 Phase 4
28 Anticoagulation in Stent Intervention Unknown status NCT01141153 Phase 4
29 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4
30 Triple Therapy in Patients on Oral Anticoagulation After Drug Eluting Stent Implantation Unknown status NCT00776633 Phase 4
31 Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients Unknown status NCT01198379 Phase 4
32 Multivessel Stenting Versus Staged Revascularization With Zotarolimus-eluting Stent for STEMI Unknown status NCT01781715 Phase 4
33 Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction Unknown status NCT00976092 Phase 4
34 DEDICA (Dose of HEparin During Coronary Angioplasty) Trial Unknown status NCT01694459 Phase 4
35 EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography Unknown status NCT01371279 Phase 4
36 Reversal of the Antithrombotic Action of New Oral Anticoagulants Unknown status NCT01478282 Phase 4
37 Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents Unknown status NCT01268371 Phase 4
38 Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI Unknown status NCT02012140 Phase 4
39 A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction Unknown status NCT01942070 Phase 4
40 Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease Unknown status NCT01418794 Phase 4
41 MGuard Stent in ST-elevation Myocardial Infarction Unknown status NCT01124942 Phase 4
42 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4
43 Fixed-dose vs. Phenotype-based PrAsugrel Dose to MATCH Therapeutic Zone in Asians With Acute Coronary Syndrome Unknown status NCT01951001 Phase 4
44 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4
45 Safety and Efficacy of Six Months Dual Antiplatelet Therapy After Drug-Eluting Stenting Unknown status NCT00661206 Phase 4
46 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4
47 ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion Unknown status NCT00407940 Phase 4
48 Assessment of Surface Coverage of Two Types of DES in Diabetes Mellitus and Non- Diabetes Mellitus Unknown status NCT01023919 Phase 4
49 Efficacy and Safety of Different Dose of Tirofiban in Interventional Treatment of Complex Coronary Artery Disease Unknown status NCT02294994 Phase 4
50 Arterial Catheter to Monitor Glycemia Unknown status NCT01176279 Phase 4

Search NIH Clinical Center for Thrombosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Thrombosis

Genetic tests related to Thrombosis:

id Genetic test Affiliating Genes
1 Thrombosis 29

Anatomical Context for Thrombosis

MalaCards organs/tissues related to Thrombosis:

39
Liver, Endothelial, Testes, Heart, Brain, Lung, Kidney

Publications for Thrombosis

Articles related to Thrombosis:

(show top 50) (show all 6743)
id Title Authors Year
1
Portomesenteric vein thrombosis after laparoscopic sleeve gastrectomy for morbid obesity. ( 28069786 )
2017
2
Tissue Factor Pathway Inhibitor-1 Is a Valuable Marker for the Prediction of Deep Venous Thrombosis and Tumor Metastasis in Patients with Lung Cancer. ( 28246607 )
2017
3
Cerebral Venous Sinus Thrombosis Presenting Feature of Systemic Lupus Erythematosus. ( 28065614 )
2017
4
Pediatric cerebral sinovenous thrombosis following cranial surgery. ( 28091816 )
2017
5
Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis. ( 28533669 )
2017
6
Brucellosis and thrombosis of the inferior vena cava. ( 27871206 )
2017
7
Patterns of retinal hemorrhage associated with pediatric cerebral sinovenous thrombosis. ( 28087346 )
2017
8
Arteriosclerosis, Thrombosis, and Vascular Biology. ( 28062452 )
2017
9
Thrombosis in a bleeding disorder: case of thromboembolism in factor VII deficiency. ( 28265390 )
2017
10
Budd-Chiari syndrome secondary to catheter-associated inferior vena cava thrombosis. ( 28355402 )
2017
11
Endovascular treatment of an unusual membranous obstruction of the inferior vena cava in Budd-Chiari syndrome complicated by mural portal vein thrombosis. ( 28483616 )
2017
12
Predictive Factors for Developing Venous Thrombosis during Cisplatin-Based Chemotherapy in Testicular Cancer. ( 28514776 )
2017
13
Portal Vein Thrombosis in the Setting of Newly Diagnosed Cushing's Syndrome. ( 28491882 )
2017
14
Acute kidney injury and risk of deep vein thrombosis and pulmonary embolism in Taiwan: A nationwide retrospective cohort study. ( 28092798 )
2017
15
Endotoxaemia-augmented murine venous thrombosis is dependent on TLR-4 and ICAM-1, and potentiated by neutropenia. ( 27975098 )
2017
16
Letter to the Editor: Lateral sinus thrombosis: antithrombotic therapy and the issue of management of cerebellar swelling. ( 27767402 )
2017
17
Melioidosis with Portal Vein Thrombosis. ( 28473933 )
2017
18
Cerebral Sinovenous Thrombosis in the Asphyxiated Cooled Infants: A Prospective Observational Study. ( 27823842 )
2017
19
Right iliac vein thrombosis mimicking acute appendicitis in pregnancy: a case report. ( 28057056 )
2017
20
A novel mutation in exon 2 of FGB caused by c.221G>T (a8 ) substitution, predicting the replacement of the native Arginine at position 74 with a Leucine (p.Arg74Leu (a8 ) ) in a proband from a Kurdish family with dysfibrinogenaemia and familial venous and arterial thrombosis. ( 27812779 )
2017
21
Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study. ( 27923178 )
2017
22
The problem with incidental and chronic portal vein thrombosis. ( 28077255 )
2017
23
Management of thrombosis in paroxysmal nocturnal hemoglobinuria: a clinician's guide. ( 28246555 )
2017
24
Effect of Post-procedural Full Does Infusion of Bivalirudin on Acute Stent Thrombosis in Patients with ST-elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Outcomes in a large real-world population. ( 28083915 )
2017
25
Activated platelet-derived and leukocyte-derived circulating microparticles and the risk of thrombosis in heparin-induced thrombocytopenia: A role for pf4-bearing microparticles? ( 28052584 )
2017
26
Atypical bone change of spine caused by epidural venous thrombosis in systemic lupus erythematosus with antiphospholipid syndrome. ( 28063414 )
2017
27
CALR exon 9 mutations in idiopathic splanchnic vein thrombosis in an Australian cohort. ( 28024182 )
2017
28
Incidence rates and case fatality rates of portal vein thrombosis and Budd-Chiari Syndrome. ( 28180235 )
2017
29
Cerebral venous thrombosis due to pheochromocytoma in a patient with Von Hippel Lindau mutation. ( 28488641 )
2017
30
Antiproteinase 3 Positive Eosinophilic Granulomatosis with Polyangiitis Presenting with Heart Failure and Intraventricular Thrombosis. ( 28251013 )
2017
31
Lateral Sinus Thrombosis: The Importance of the Unaffected Sinus. ( 26853232 )
2016
32
Management of portal vein thrombosis in cirrhosis: More shadows than lights. ( 27053401 )
2016
33
Necrotic Gastric Gangrene as Complication of Congestive Portal Venopathy from Portal Vein Thrombosis. ( 27622195 )
2016
34
ST-elevation myocardial infarction in a young adult secondary to giant coronary aneurysm thrombosis: an important sequela of Kawasaki disease and a management challenge. ( 26791126 )
2016
35
Portal vein thrombosis in patients with cirrhosis: just a common finding or a predictor of poor outcome? ( 27740524 )
2016
36
Remarks about the study of an unusual presentation of venous thrombosis in a child with idiopathic membranous nephropathy. ( 27215268 )
2016
37
Cavernous Sinus Thrombosis due to Streptococcus mitis and Staphylococcus lugdunensis. ( 27790500 )
2016
38
Portal vein thrombosis relevance on liver cirrhosis: Italian Venous Thrombotic Events Registry. ( 27026379 )
2016
39
Correlative study between the JAK2V617F mutation and thrombosis in patients with myeloproliferative neoplasm. ( 27706633 )
2016
40
Prevalence of Isolated Asymptomatic Deep Vein Thrombosis in Varicose Vein Patients with Superficial Thrombophlebitis: A Single Center Experience in Japan. ( 27087866 )
2016
41
Cerebral venous thrombosis and secondary polycythemia in a case of nephrotic syndrome. ( 26997397 )
2016
42
Management of portal vein thrombosis in cirrhosis: an update. ( 27075588 )
2016
43
Predictors for the development of post-thrombotic syndrome in patients with primary lower limb deep venous thrombosis: A case-control study. ( 27083699 )
2016
44
Plasma homocysteine levels, methylene tetrahydrofolate reductase A1298C gene polymorphism and risk of retinal vein thrombosis. ( 26650461 )
2016
45
Optical Coherence Tomography Findings in Early Stent Thrombosis by Heparin-Induced Thrombocytopenia. ( 27818479 )
2016
46
Cerebral Sinovenous Thrombosis in Neonates and Children. ( 27396366 )
2016
47
Dysfunctional coagulation and fibrinolysis systems due to adenomyosis is a possible cause of thrombosis and menorrhagia. ( 27543913 )
2016
48
Disseminated Renal Burkitt Lymphoma With Malignant Inferior Vena Caval Thrombosis in a Child. ( 26993348 )
2016
49
Disseminated intravascular coagulation at diagnosis is a strong predictor for both arterial and venous thrombosis in newly diagnosed acute myeloid leukemia. ( 27354723 )
2016
50
Paralytic Ileus due to Superior Mesenteric Venous Thrombosis after Transarterial Injection for Hepatocellular Carcinoma. ( 26726083 )
2016

Variations for Thrombosis

Expression for Thrombosis

Search GEO for disease gene expression data for Thrombosis.

Pathways for Thrombosis

Pathways related to Thrombosis according to GeneCards Suite gene sharing:

(show all 16)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.21 APOH F10 F2 F3 F5 F7
2
Show member pathways
12.74 F10 F2 F3 F5 F7 F9
3
Show member pathways
12.21 F2 F7 MTHFR PLAT SERPINE1
4
Show member pathways
12.13 F2 GP6 PROC PROS1 SELP THBD
5
Show member pathways
12.04 F10 F2 F3 F5 F7 F9
6 11.9 GP1BA GP6 P2RY12 VWF
7
Show member pathways
11.88 F10 F2 F7 F9 PROC PROS1
8 11.79 F3 JAK2 SERPINE1 THBD
9
Show member pathways
11.73 F2 GP1BA VWF
10 11.58 F10 F2 F3 F5 F7 F9
11 11.44 F2 GP6 P2RY12 VWF
12 11.38 GP1BA PLAT SELP
13 10.91 F10 F2 F7 F9 PROC PROS1
14 10.75 GP1BA GP6 VWF
15 10.66 PLAT SERPINE1
16 10.54 GP1BA VWF

GO Terms for Thrombosis

Cellular components related to Thrombosis according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 9.89 APOH F3 PLAT SERPINE1 VWF
2 cell surface GO:0009986 9.87 APOH F3 GP1BA GP6 P2RY12 PLAT
3 platelet alpha granule lumen GO:0031093 9.71 F5 PROS1 SERPINE1 VWF
4 endoplasmic reticulum lumen GO:0005788 9.7 F10 F2 F5 F7 F9 PROC
5 platelet alpha granule GO:0031091 9.51 F5 VWF
6 intrinsic component of external side of plasma membrane GO:0031233 9.48 F10 F3
7 extracellular space GO:0005615 9.44 APOH F2 F3 F5 F7 F9
8 serine-type peptidase complex GO:1905286 9.43 F3 F7
9 Golgi lumen GO:0005796 9.43 F10 F2 F7 F9 PROC PROS1
10 plasma membrane GO:0005886 10.24 F10 F2 F3 F5 F7 F9
11 extracellular exosome GO:0070062 10.2 APOH F2 F3 F9 GP1BA GP6
12 extracellular region GO:0005576 10.07 APOH F10 F2 F3 F5 F7

Biological processes related to Thrombosis according to GeneCards Suite gene sharing:

(show all 26)
id Name GO ID Score Top Affiliating Genes
1 platelet activation GO:0030168 9.97 F2 F5 GP1BA GP6 P2RY12 VWF
2 cellular protein metabolic process GO:0044267 9.91 F2 F5 PROC SERPINC1
3 positive regulation of cell migration GO:0030335 9.88 F10 F3 F7 JAK2
4 blood coagulation GO:0007596 9.86 F10 F2 F3 F5 F7 F9
5 regulation of blood coagulation GO:0030193 9.84 APOH F2 GP1BA SERPINC1
6 positive regulation of blood coagulation GO:0030194 9.81 APOH F2 F7 SERPINE1
7 positive regulation of protein kinase B signaling GO:0051897 9.8 F10 F3 F7
8 fibrinolysis GO:0042730 9.8 F2 GP1BA PLAT PROS1 SERPINE1
9 signal peptide processing GO:0006465 9.8 F10 F2 F7 F9 PROC PROS1
10 negative regulation of fibrinolysis GO:0051918 9.78 APOH F2 SERPINE1 THBD
11 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.77 F2 JAK2 SELP
12 negative regulation of blood coagulation GO:0030195 9.77 APOH PROC PROS1 SERPINE1 THBD
13 blood coagulation, extrinsic pathway GO:0007598 9.73 F10 F3 F7 F9
14 blood coagulation, intrinsic pathway GO:0007597 9.73 APOH F10 F2 F9 GP1BA VWF
15 positive regulation of positive chemotaxis GO:0050927 9.63 F3 F7
16 peptidyl-glutamic acid carboxylation GO:0017187 9.63 F10 F2 F7 F9 PROC PROS1
17 enzyme linked receptor protein signaling pathway GO:0007167 9.62 GP6 JAK2
18 plasminogen activation GO:0031639 9.61 APOH PLAT
19 negative regulation of platelet activation GO:0010544 9.6 F2 THBD
20 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.58 F3 F7
21 response to vitamin K GO:0032571 9.57 F5 F7
22 hemostasis GO:0007599 9.47 F10 F2 F3 F5 F7 F9
23 proteolysis GO:0006508 10.1 F10 F2 F5 F7 F9 PLAT
24 leukocyte migration GO:0050900 10.02 F2 GP6 PROC PROS1 SELP THBD
25 platelet degranulation GO:0002576 10 APOH F5 PROS1 SELP SERPINE1 VWF
26 ER to Golgi vesicle-mediated transport GO:0006888 10 F10 F2 F5 F7 F9 PROC

Molecular functions related to Thrombosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.87 F10 F2 F7 F9 PROC PROS1
2 peptidase activity GO:0008233 9.85 F10 F2 F7 F9 PLAT PROC
3 receptor binding GO:0005102 9.83 F2 F7 JAK2 PLAT SERPINE1
4 heparin binding GO:0008201 9.71 APOH F2 SELP SERPINC1
5 phospholipid binding GO:0005543 9.63 APOH F10 F3
6 serine-type peptidase activity GO:0008236 9.63 F10 F2 F7 F9 PLAT PROC
7 protease binding GO:0002020 9.56 F3 SERPINC1 SERPINE1 VWF
8 glycoprotein binding GO:0001948 9.35 APOH F7 PLAT SELP VWF
9 serine-type endopeptidase activity GO:0004252 9.23 F10 F2 F3 F5 F7 F9

Sources for Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
41