MCID: THR024
MIFTS: 61

Thrombosis

Categories: Blood diseases, Cardiovascular diseases

Aliases & Classifications for Thrombosis

MalaCards integrated aliases for Thrombosis:

Name: Thrombosis 12 28 51 3 69
Thrombosis of Blood Vessel 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0060903

Summaries for Thrombosis

Disease Ontology : 12 A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.

MalaCards based summary : Thrombosis, also known as thrombosis of blood vessel, is related to sagittal sinus thrombosis and intracranial sinus thrombosis. An important gene associated with Thrombosis is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Dalteparin and Heparin have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and testes, and related phenotypes are homeostasis/metabolism and cardiovascular system

CDC : 3 Many people who have or have had family members with hemophilia will ask that their baby boys get tested soon after birth.

Related Diseases for Thrombosis

Diseases related to Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 998)
# Related Disease Score Top Affiliating Genes
1 sagittal sinus thrombosis 33.8 F2 F3 F5 SERPINC1
2 intracranial sinus thrombosis 33.7 F3 SERPINC1
3 portal vein thrombosis 33.4 APOH F2 F5 JAK2 MTHFR SERPINC1
4 cerebral sinovenous thrombosis 33.4 APOH F2 F3 F5 PROS1
5 intracranial thrombosis 33.3 APOH F3 F5 MTHFR SERPINC1 VWF
6 carotid artery thrombosis 33.2 F10 F3 PLAT SERPINE1
7 coronary thrombosis 33.1 F3 GP1BA PLAT SERPINC1 SERPINE1 VWF
8 budd-chiari syndrome 32.6 APOH F2 F3 F5 JAK2 MTHFR
9 heparin-induced thrombocytopenia 32.5 F10 F3 SERPINC1
10 may-thurner syndrome 32.4 APOH F5
11 post-thrombotic syndrome 32.3 F2 F5 SERPINC1 SERPINE1
12 dysfibrinogenemia 32.2 F2 F5 PLAT SERPINC1 THBD
13 thrombocytosis 32.1 F2 F3 JAK2 SERPINC1
14 factor v deficiency 32.0 F2 F3 F5 F9
15 shwartzman phenomenon 31.9 F3 SERPINE1 THBD
16 buerger disease 31.9 APOH F2 MTHFR SERPINE1
17 hepatic veno-occlusive disease 31.9 F3 PLAT SERPINC1 SERPINE1 THBD
18 homocysteinemia 31.8 F2 F5 MTHFR SERPINC1 SERPINE1
19 varicose veins 31.7 F2 F5 MTHFR SERPINC1 VWF
20 plasminogen activator inhibitor-1 deficiency 31.7 PLAT SERPINE1
21 factor vii deficiency 31.6 F10 F2 F3 F9
22 protein s deficiency 31.5 APOH F2 F3 F5 MTHFR PROS1
23 catastrophic antiphospholipid syndrome 31.5 APOH F3 F5 MTHFR PROC SERPINE1
24 protein z deficiency 31.5 F10 SERPINA10
25 essential thrombocythemia 31.4 F2 F3 JAK2 SERPINE1 THBD VWF
26 antithrombin iii deficiency 31.4 APOH F10 F2 F5 MTHFR SERPINC1
27 thrombophilia due to thrombin defect 31.0 APOH F10 F2 F3 F5 MTHFR
28 antiphospholipid syndrome 31.0 APOH F10 F2 F3 F5 MTHFR
29 protein c deficiency 30.8 F2 F5 F9 HRG MTHFR PROC
30 thrombocytopenia 30.6 APOH F3 GP1BA THBD
31 homocystinuria 30.5 F5 MTHFR SERPINC1
32 portal hypertension 30.4 F2 JAK2 VWF
33 lemierre's syndrome 30.4 F3 MTHFR SERPINE1
34 pulmonary embolism 30.3 APOH F10 F2 F3 F5 F9
35 splenic infarction 30.2 APOH F2
36 carotid artery occlusion 30.2 APOH F5 THBD
37 vein disease 30.1 F2 F3 F5 MTHFR PLAT PROC
38 acute myocardial infarction 30.1 F3 PLAT SERPINC1 SERPINE1 VWF
39 endocarditis 30.1 APOH F2 SERPINC1
40 venous insufficiency 29.9 F2 PLAT SERPINE1 VWF
41 factor xii deficiency 29.8 APOH F3 F5 F9 SERPINC1
42 thrombophlebitis 29.8 APOH F2 F5 MTHFR PLAT SERPINC1
43 sticky platelet syndrome 29.8 F5 SERPINC1 SERPINE1
44 stroke, ischemic 29.8 APOH F2 F3 F5 MTHFR PLAT
45 eisenmenger syndrome 29.8 PLAT THBD VWF
46 neonatal stroke 29.7 MTHFR PROC SERPINE1
47 patent foramen ovale 29.7 APOH F2 F5 MTHFR PLAT SERPINC1
48 cerebral palsy 29.7 F2 F5 MTHFR
49 factor xi deficiency 29.7 F2 F3 F9 SERPINC1
50 vasculitis 29.7 APOH THBD VWF

Graphical network of the top 20 diseases related to Thrombosis:



Diseases related to Thrombosis

Symptoms & Phenotypes for Thrombosis

MGI Mouse Phenotypes related to Thrombosis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.32 F3 MTHFR PLAT F5 APOH F9
2 cardiovascular system MP:0005385 10.3 F3 PLAT F5 F9 F10 F2
3 hematopoietic system MP:0005397 10.22 F3 PLAT CD55 F9 GP1BA F2
4 immune system MP:0005387 10.1 F3 PLAT CD55 F9 F2 JAK2
5 embryo MP:0005380 10.09 JAK2 F3 F5 F9 F2 THBD
6 integument MP:0010771 9.96 F3 MTHFR PLAT F5 F2 JAK2
7 mortality/aging MP:0010768 9.89 F3 MTHFR PLAT F5 APOH F9
8 liver/biliary system MP:0005370 9.76 JAK2 F5 F9 THBD SERPINC1 SERPINE1
9 nervous system MP:0003631 9.4 VWF MTHFR F3 F5 F2 SERPINA10

Drugs & Therapeutics for Thrombosis

Drugs for Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 891)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dalteparin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6
2
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6 46507594 772
3
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128270-60-0 16129704
4
Tenecteplase Approved Phase 4,Phase 3,Phase 2,Phase 1 191588-94-0
5
Tirofiban Approved Phase 4,Phase 3,Phase 2 144494-65-5 60947
6
Phenprocoumon Approved, Investigational Phase 4,Phase 3,Phase 2 435-97-2 54680692 9908
7
Abciximab Approved Phase 4,Phase 3,Phase 2 143653-53-6
8
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
9 Nadroparin Approved, Investigational Phase 4,Phase 3,Phase 2 9041-08-1
10
Warfarin Approved Phase 4,Phase 3,Phase 2,Phase 1 81-81-2 54678486 6691
11
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 120202-66-6, 113665-84-2 60606
12
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 274693-27-5 9871419
13
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
14
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
15
Thrombin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1
16
Phenobarbital Approved, Investigational Phase 4 50-06-6 4763
17
Alprostadil Approved, Investigational Phase 4,Phase 3,Phase 2 745-65-3 149351
18
Rivaroxaban Approved Phase 4,Phase 3,Phase 2,Phase 1 366789-02-8
19
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1 1197-18-8 5526
20
Tranylcypromine Approved, Investigational Phase 4,Phase 3 155-09-9 441233
21
Nicorandil Approved, Investigational Phase 4 65141-46-0 47528
22 Fondaparinux Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 104993-28-4
23
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2 50-28-2 5757
24
Norethindrone Approved Phase 4 68-22-4 6230
25
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
26
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 69-72-7 338
27
Acenocoumarol Approved, Investigational Phase 4,Phase 3 152-72-7 54676537 9052
28
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 73590-58-6 4594
29
Pantoprazole Approved Phase 4,Phase 3,Phase 1 102625-70-7 4679
30
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
31
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 46835353 6436030 5284616
32
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
33
Chromium Approved Phase 4,Phase 2,Phase 3 7440-47-3 27668
34
Nitric Oxide Approved Phase 4,Phase 2,Phase 3,Phase 1 10102-43-9 145068
35
Coal tar Approved Phase 4,Phase 2,Phase 3,Phase 1 8007-45-2
36
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 55-56-1 2713 9552079
37
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2 61825-94-3 43805 6857599 5310940 9887054
38
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 188627-80-7 123610
39
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 3 71-58-9
40 Certoparin Approved, Investigational Phase 4,Phase 3
41
Progesterone Approved, Vet_approved Phase 4,Phase 3 57-83-0 5994
42
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 216974-75-3
43
Ranibizumab Approved Phase 4,Phase 2,Phase 3,Phase 1 347396-82-1 459903
44
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
45
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 124-94-7 31307
46
Tinzaparin Approved Phase 4,Phase 3,Phase 2 9041-08-1, 9005-49-6 25244225
47
Cisplatin Approved Phase 4,Phase 3,Phase 2 15663-27-1 2767 441203 84093
48
Ethiodized oil Approved, Investigational Phase 4,Phase 3,Phase 2 8008-53-5
49 Edoxaban Approved Phase 4,Phase 3,Phase 2,Phase 1 480449-70-5
50
Ezetimibe Approved Phase 4 163222-33-1 150311

Interventional clinical trials:

(show top 50) (show all 4037)

# Name Status NCT ID Phase Drugs
1 Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis Unknown status NCT00450645 Phase 4 low molecular weight heparin
2 Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis Unknown status NCT01252420 Phase 4 Enoxaparin
3 Rosuvastatin for Preventing Deep Vein Thrombosis Unknown status NCT01021488 Phase 4 Rosuvastatin 20mg/d for 14days;enoxaparin only
4 Intracoronary Cocktail Injection Combined With Thrombus Aspiration in STEMI Patients Treated With Primary Angioplasty Unknown status NCT02592694 Phase 4 cocktail
5 Left Atrial Thrombus Reduction - Effect of Dabigatran Versus Phenprocoumon Unknown status NCT02591225 Phase 4 Dabigatranetexilate;Phenprocoumon
6 Safety and Efficacy Study of OmniWave Endovascular System to Treat Deep Vein Thrombosis Unknown status NCT00640731 Phase 4
7 Resolution of Left Atrial-Appendage Thrombus - Effects of Dabigatran in Patients With AF Unknown status NCT02256683 Phase 4 Dabigatran etexilate;Phenprocoumon
8 Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users Unknown status NCT01063426 Phase 4 High dose Atorvastatin+enoxaparin;Enoxaparin
9 Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Unknown status NCT01383785 Phase 4
10 The Effect of Anticoagulation After Endoscopic Therapy in Cirrhotic Patients With Portal Vein Thrombosis Unknown status NCT02398357 Phase 4 Nadroparin Calcium and Warfarin
11 Thrombus Aspiration in Patients With STEMI Unknown status NCT02606435 Phase 4
12 Rapid P2Y12 Receptor Inhibition Attenuates Inflammatory Cell Infiltration in Thrombus Aspirated From the STEMI Patients Unknown status NCT02639143 Phase 4 ticagrelor;Clopidogrel
13 Hormones Inflammation and Thrombosis Unknown status NCT01875185 Phase 4 Aspirin 81 mg PO daily x 7 days
14 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Unknown status NCT01245998 Phase 4 Dalteparin;Dalteparin
15 Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Non-ST-elevation Myocardial Infarction Study Unknown status NCT01013038 Phase 4
16 Hepatic Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Complicated by Portal Vein Tumor Thrombosis Unknown status NCT01350206 Phase 4
17 Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study. Unknown status NCT01914055 Phase 4
18 Antiaggregation in Primary Prevention of Vascular Access for Hemodialysis Unknown status NCT02055131 Phase 4 aspirin
19 Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery Unknown status NCT00983112 Phase 4 Human Fibrinogen and human thrombin (Evicel);Sodium Chlorure (Physiological saline)
20 Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside) Unknown status NCT00963781 Phase 4 Reduced duration (6 months) DAPT
21 Low Molecular Weight Heparin in Prevention of Recurrent Arteriovenous Graft Thrombosis in Chronic Hemodialysis Patients. Unknown status NCT01970280 Phase 4 Enoxaparin
22 Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA Unknown status NCT01670474 Phase 4 rt-PA (2mg/2mL) actilysis;rt-PA
23 Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction Unknown status NCT01156662 Phase 4
24 Randomized Trial of Standard vs ClearWay-infused Abciximab and Thrombectomy for Myocardial Infarction Unknown status NCT01499407 Phase 4 Abciximab
25 The Use of Prostaglandin E1 in Head and Neck Microsurgery Unknown status NCT00733434 Phase 4 Prostaglandin E1
26 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4 Tranexamic Acid 5%,5ml/amp;Tranexamic Acid 5%,5ml/amp;rivaroxaban (10mg);0.9% Normal Saline;0.9% Normal Saline
27 Late Incomplete Stent Apposition Evaluation II: Comparison Between Polimer-based and No-polimer Stent System. IVUS Based Study Unknown status NCT01375855 Phase 4
28 Randomised Controlled Trial of Needle Free Access Devices in Preventing Hemodialysis Blood Stream Infection Unknown status NCT01082770 Phase 4
29 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4 Nicorandil;normal saline
30 Effectiveness of Blood Clot Medication With Concomitant Blood Pressure Medication Unknown status NCT00424281 Phase 4 Arixtra (fondaparinux), 2.5 mg/day-what is bioavailability
31 Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy Unknown status NCT02264743 Phase 4 Femoston Conti;EVOREL® CONTI
32 Monitoring Response to Antiplatelet Therapy Unknown status NCT00327041 Phase 4
33 Cost Effectiveness Analysis In Patients With Heart Valve Prosthesis Unknown status NCT02022527 Phase 4 Acetyl Salicylic Acid;Warfarin;Placebo (for Aspirin)
34 Anticoagulation in Stent Intervention Unknown status NCT01141153 Phase 4 Acetylsalicylic Acid + clopidogrel + acenocoumarol;Acetylsalicylic Acid + clopidogrel
35 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4 omeprazole;Pantoprazole
36 Triple Therapy in Patients on Oral Anticoagulation After Drug Eluting Stent Implantation Unknown status NCT00776633 Phase 4 aspirin;clopidogrel;oral anticoagulation
37 Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients Unknown status NCT01198379 Phase 4 aspirin;Placebo
38 Multivessel Stenting Versus Staged Revascularization With Zotarolimus-eluting Stent for STEMI Unknown status NCT01781715 Phase 4
39 Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease Study Unknown status NCT02642419 Phase 4 Rivaroxaban and single antiplatelet drug (aspirin, clopidogrel or prasugrel);Rivaroxaban
40 Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction Unknown status NCT00976092 Phase 4 Prasugrel;Bivalirudin;Clopidogrel;Heparin
41 DEDICA (Dose of HEparin During Coronary Angioplasty) Trial Unknown status NCT01694459 Phase 4 Low-dose heparin;Standard dose heparin
42 EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography Unknown status NCT01371279 Phase 4
43 Reversal of the Antithrombotic Action of New Oral Anticoagulants Unknown status NCT01478282 Phase 4 Rivaroxaban;Dabigatran
44 Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI Unknown status NCT02012140 Phase 4 ticagrelor
45 Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents Unknown status NCT01268371 Phase 4
46 A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction Unknown status NCT01942070 Phase 4
47 Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease Unknown status NCT01418794 Phase 4
48 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4
49 Fixed-dose vs. Phenotype-based PrAsugrel Dose to MATCH Therapeutic Zone in Asians With Acute Coronary Syndrome Unknown status NCT01951001 Phase 4 Prasugrel
50 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4 Microbubbles

Search NIH Clinical Center for Thrombosis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Genetic Tests for Thrombosis

Genetic tests related to Thrombosis:

# Genetic test Affiliating Genes
1 Thrombosis 28

Anatomical Context for Thrombosis

MalaCards organs/tissues related to Thrombosis:

38
Liver, Heart, Testes, Endothelial, Lung, Kidney, Brain

Publications for Thrombosis

Articles related to Thrombosis:

(show top 50) (show all 6974)
# Title Authors Year
1
rLj-RGD3, a novel recombinant toxin protein from Lampetra japonica, prevents coronary thrombosis-induced acute myocardial infarction by inhibiting platelet functions in rats. ( 29407168 )
2018
2
Aneurysm of the inferior vena cava with thrombosis. ( 29445486 )
2018
3
Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis. ( 29445199 )
2018
4
Gastrointestinal: Duodenal variceal bleeding secondary to thrombophilia-related portal vein thrombosis. ( 29372608 )
2018
5
Regenerative nodular hyperplasia, portal vein thrombosis and primary myelofibrosis: An unusual triple association. ( 29368941 )
2018
6
Diagnosis and Treatment of Cerebral Venous Thrombosis: A Review. ( 29441008 )
2018
7
Successful Use of Intravenous Immunoglobulin G to Treat Refractory Heparin-Induced Thrombocytopenia With Thrombosis Complicating Peripheral Blood Stem Cell Harvest. ( 29404376 )
2018
8
Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity. ( 29444200 )
2018
9
The disseminated intravascular coagulation score is a novel predictor for portal vein thrombosis in cirrhotic patients with hepatitis B. ( 29178991 )
2018
10
Bland or tumor pulmonary artery stump thrombosis? ( 29448832 )
2018
11
Polymorphism in dural arteriovenous fistula: Matrix Metalloproteinase-2-1306 C/T as a potential risk factor for sinus thrombosis. ( 29431912 )
2018
12
The use of nonselective beta blockers is a risk factor for portal vein thrombosis in cirrhotic patients. ( 29451181 )
2018
13
Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study. ( 29427117 )
2018
14
The association between nonselective beta-blockers and portal venous thrombosis in cirrhotic patients: More questions on the horizon. ( 29451177 )
2018
15
What Are the Benefits of Anticoagulation for Portal VeinA Thrombosis in Individuals With Cirrhosis? ( 29352956 )
2018
16
Arteriosclerosis, Thrombosis, and Vascular Biology. ( 29282242 )
2018
17
Prospective longitudinal quality of life and survival outcomes in patients with advanced infiltrative hepatocellular carcinoma and portal vein thrombosis treated with Yttrium-90 radioembolization. ( 29329568 )
2018
18
Clinical and neuroimaging characteristics of cerebral sinovenous thrombosis in neonates undergoing cardiac surgery. ( 29221746 )
2018
19
Pediatric dural venous sinus thrombosis following closed head injury: an easily overlooked diagnosis with devastating consequences. ( 29350373 )
2018
20
Thoracic outlet syndrome presenting with subclavian vein thrombosis. ( 29369936 )
2018
21
Successful treatment of extensive splanchnic vein thrombosis in a patient with mycosis fungoides. ( 29437735 )
2018
22
Phase II Study of Sorafenib Combined with Concurrent Hepatic Arterial Infusion of Oxaliplatin, 5-Fluorouracil and Leucovorin for Unresectable Hepatocellular Carcinoma with Major Portal Vein Thrombosis. ( 29327075 )
2018
23
Risk of Venous Thrombosis in Antithrombin Deficiency: A Systematic Review and Bayesian Meta-analysis. ( 29452444 )
2018
24
An assessment of deep venous thrombosis in Irish older adults in an acute medical assessment unit. ( 29441431 )
2018
25
Endoscopic ultrasound-guided fine-needle aspiration of portal vein thrombosis in patients with chronic liver disease and suspicion of hepatocellular carcinoma. ( 29420366 )
2018
26
Thrombosis of the spleno-mesentiric portal axis following laparoscopic sleeve gastrectomy: A rare case report. ( 29438854 )
2018
27
Response to Portal vein thrombosis after hepatitis C eradication with direct acting antiviral therapy. ( 29272568 )
2018
28
A rare case of renal vein thrombosis secondary to<i>Klebsiella pneumoniae</i>pyelonephritis. ( 29416285 )
2018
29
Low-molecular-weight heparin treatment for portal vein thrombosis in liver cirrhosis: Efficacy and the risk of hemorrhagic complications. ( 29407630 )
2018
30
Anticoagulation for Portal Vein Thrombosis in Liver Cirrhosis: Not Only Recanalize the PortalA Vein. ( 29351835 )
2018
31
Ischaemic Events and Stent Thrombosis following Planned Discontinuation of Study Treatment with Ticagrelor or Clopidogrel in the PLATO Study. ( 29443375 )
2018
32
Sodium lactate improves renal microvascular thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an experimental randomized open label controlled study. ( 29445877 )
2018
33
Serial long term follow up of a medically managed aortic prosthetic valve thrombosis. ( 29452310 )
2018
34
Clot structure predicts recurrent thrombosis. ( 29449303 )
2018
35
Locked-in Syndrome and<sup>18</sup>F-fluorodeoxyglucose-positron Emission Tomography/Computed Tomography: Observations from a Case of Basilar Artery Thrombosis. ( 29430121 )
2018
36
Endovascular clot retrieval in extensive cerebral venous sinus thrombosis (CVST): a videographic report. ( 29445500 )
2018
37
Renal vein thrombosis complicating severe acute pyelonephritis with renal abscesses and associated bacteraemia caused by extended-spectrum beta-lactamase producing Escherichia coli. ( 29327131 )
2018
38
Liver Atrophy and Regeneration in Non-Cirrhotic Portal Vein Thrombosis: Effect of Surgical Shunts. ( 29377486 )
2018
39
Portal vein thrombosis: yes or no on anticoagulation therapy. ( 29432256 )
2018
40
Direct oral anticoagulant use in patients with thrombophilia, antiphospholipid syndrome or venous thrombosis of unusual sites: A narrative review. ( 29402471 )
2018
41
Missed Massive Pulmonary Embolism and the Hidden Threat of a Distal Deep Vein Thrombosis. ( 29435465 )
2018
42
Anticoagulation for Portal VeinA Thrombosis in Cirrhosis: Selection of Appropriate Patients. ( 29351830 )
2018
43
Reversible bioprosthetic valve thrombosis from eosinophilia. ( 29437808 )
2018
44
Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) as a Risk Factor for Arterial Thrombosis in Georgian Patients. ( 29439641 )
2018
45
Acquired hemophilia with thrombosis in a cancer patient: an unusual presentation. ( 29095762 )
2018
46
Coexistent Ipsilateral Internal Carotid Artery Occlusion and Cerebral Venous Thrombosis in Hepatitis C. ( 29349091 )
2018
47
Late diagnosis of homocystinuria in an adult after extensive cerebral venous thrombosis. ( 29175875 )
2018
48
Tissue plasminogen activator for neonatal coronary thrombosis presenting with mitral valve regurgitation and impaired ventricular function. ( 28140523 )
2017
49
Familial antithrombin III deficiency in a Malay patient with massive thrombosis. ( 28866705 )
2017
50
Thrombosis in adult patients with acute leukemia. ( 28841588 )
2017

Variations for Thrombosis

Expression for Thrombosis

Search GEO for disease gene expression data for Thrombosis.

Pathways for Thrombosis

Pathways related to Thrombosis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.16 APOH F10 F2 F3 F5 F9
2
Show member pathways
12.74 F10 F2 F3 F5 F9 PROC
3
Show member pathways
12.11 F2 MTHFR PLAT SERPINE1
4
Show member pathways
12.01 F2 PROC PROS1 THBD
5 11.94 CD55 F10 F2 F3 F5 F9
6
Show member pathways
11.8 F10 F2 F9 PROC PROS1
7 11.73 F3 JAK2 SERPINE1 THBD
8
Show member pathways
11.69 F2 GP1BA VWF
9
Show member pathways
11.67 F10 F2 F3 F5 F9 GP1BA
10 10.83 F10 F2 F9 PROC PROS1
11 10.69 HRG PLAT SERPINE1
12 10.62 GP1BA VWF
13 10.49 GP1BA VWF

GO Terms for Thrombosis

Cellular components related to Thrombosis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.92 APOH CD55 F3 GP1BA HRG PLAT
2 extracellular matrix GO:0031012 9.88 APOH F3 PLAT SERPINE1 VWF
3 blood microparticle GO:0072562 9.8 F2 HRG PROS1 SERPINC1
4 endoplasmic reticulum lumen GO:0005788 9.8 F10 F2 F5 F9 PROC SERPINA10
5 Golgi lumen GO:0005796 9.77 F10 F2 F9 PROC PROS1
6 extracellular space GO:0005615 9.77 APOH F2 F3 F5 F9 PLAT
7 platelet alpha granule lumen GO:0031093 9.55 F5 HRG PROS1 SERPINE1 VWF
8 extracellular region GO:0005576 9.53 APOH CD55 F10 F2 F3 F5
9 platelet alpha granule GO:0031091 9.51 F5 VWF
10 intrinsic component of external side of plasma membrane GO:0031233 9.46 F10 F3
11 plasma membrane GO:0005886 10.28 CD55 F10 F2 F3 F5 F9
12 extracellular exosome GO:0070062 10.22 APOH CD55 F2 F3 F9 GP1BA

Biological processes related to Thrombosis according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.99 APOH F5 HRG PROS1 SERPINE1 VWF
2 cellular protein metabolic process GO:0044267 9.95 F2 F5 PROC SERPINA10 SERPINC1
3 leukocyte migration GO:0050900 9.89 F2 PROC PROS1 THBD
4 regulation of blood coagulation GO:0030193 9.88 APOH F2 GP1BA HRG SERPINC1
5 negative regulation of peptidase activity GO:0010466 9.87 SERPINA10 SERPINC1 SERPINE1 TFPI
6 platelet activation GO:0030168 9.86 F2 GP1BA HRG VWF
7 blood coagulation GO:0007596 9.86 F10 F2 F3 F5 F9 GP1BA
8 signal peptide processing GO:0006465 9.83 F10 F2 F9 PROC PROS1
9 peptidyl-glutamic acid carboxylation GO:0017187 9.8 F10 F2 F9 PROC PROS1
10 fibrinolysis GO:0042730 9.8 F2 GP1BA HRG PLAT PROS1 SERPINE1
11 regulation of complement activation GO:0030449 9.78 CD55 F2 PROS1
12 negative regulation of fibrinolysis GO:0051918 9.77 APOH F2 HRG SERPINE1 THBD
13 blood coagulation, extrinsic pathway GO:0007598 9.76 F10 F3 F9 TFPI
14 blood coagulation, intrinsic pathway GO:0007597 9.73 APOH F10 F2 F9 GP1BA VWF
15 positive regulation of blood coagulation GO:0030194 9.71 APOH F2 SERPINE1
16 negative regulation of blood coagulation GO:0030195 9.63 APOH PROC PROS1 SERPINE1 TFPI THBD
17 plasminogen activation GO:0031639 9.6 APOH PLAT
18 negative regulation of cell adhesion mediated by integrin GO:0033629 9.58 HRG SERPINE1
19 negative regulation of platelet activation GO:0010544 9.58 F2 THBD
20 hemostasis GO:0007599 9.47 F10 F2 F3 F5 F9 GP1BA
21 ER to Golgi vesicle-mediated transport GO:0006888 10.04 CD55 F10 F2 F5 F9 PROC
22 negative regulation of endopeptidase activity GO:0010951 10 HRG PROS1 SERPINA10 SERPINC1 SERPINE1 TFPI

Molecular functions related to Thrombosis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.91 F10 F2 F9 PROC PROS1 THBD
2 peptidase activity GO:0008233 9.89 F10 F2 F9 PLAT PROC
3 receptor binding GO:0005102 9.85 F2 HRG JAK2 PLAT SERPINE1
4 peptidase inhibitor activity GO:0030414 9.71 SERPINA10 SERPINC1 SERPINE1 TFPI
5 phospholipid binding GO:0005543 9.65 APOH F10 F3
6 heparin binding GO:0008201 9.65 APOH F2 HRG SERPINA10 SERPINC1
7 protease binding GO:0002020 9.62 F3 SERPINC1 SERPINE1 VWF
8 serine-type peptidase activity GO:0008236 9.55 F10 F2 F9 PLAT PROC
9 serine-type endopeptidase activity GO:0004252 9.43 F10 F2 F3 F9 PLAT PROC
10 immunoglobulin binding GO:0019865 9.37 HRG VWF
11 serine-type endopeptidase inhibitor activity GO:0004867 9.02 HRG SERPINA10 SERPINC1 SERPINE1 TFPI

Sources for Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
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47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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