MCID: THR005
MIFTS: 53

Thrombotic Thrombocytopenic Purpura malady

Genetic diseases, Nephrological diseases, Blood diseases, Rare diseases, Immune diseases categories

Aliases & Classifications for Thrombotic Thrombocytopenic Purpura

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Sources:
9Disease Ontology, 21Genetics Home Reference, 11DISEASES, 47Orphanet, 60UMLS, 33MeSH, 55SNOMED-CT, 38NCIt, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Thrombotic Thrombocytopenic Purpura, Aliases & Descriptions:

Name: Thrombotic Thrombocytopenic Purpura 9 21 11 47
Purpura, Thrombotic Thrombocytopenic 21 60
Microangiopathic Hemolytic Anemia 21 60
Ttp 21 47
Congenital Thrombotic Thrombocytopenic Purpura 60
Familial Thrombotic Thrombocytopenic Purpura 60
 
Familial Thrombotic Thrombocytopenia Purpura 21
Thrombotic Microangiopathy, Familial 21
Moschcowitz's Syndrome 9
Moschcowitz Disease 47
Moschkowitz Disease 21


Classifications:



Characteristics (Orphanet epidemiological data):

47
thrombotic thrombocytopenic purpura:
Inheritance: Autosomal recessive,Multigenic/multifactorial; Prevalence: 1-9/1000000 (United States),1-5/10000 (Europe),1-9/1000000 (United Kingdom),1-9/1000000 (Europe); Age of onset: All ages; Age of death: any age


External Ids:

Disease Ontology9 DOID:10772
MeSH33 D011697
NCIt38 C78797
Orphanet47 54057
MESH via Orphanet34 D011697
ICD10 via Orphanet26 M31.1
UMLS via Orphanet61 C0034155

Summaries for Thrombotic Thrombocytopenic Purpura

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Genetics Home Reference:21 Thrombotic thrombocytopenic purpura is a rare disorder that causes blood clots (thrombi) to form in small blood vessels throughout the body. These clots can cause serious medical problems if they block vessels and restrict blood flow to organs such as the brain, kidneys, and heart. Resulting complications can include neurological problems (such as personality changes, headaches, confusion, and slurred speech), fever, abnormal kidney function, abdominal pain, and heart problems.

MalaCards based summary: Thrombotic Thrombocytopenic Purpura, also known as purpura, thrombotic thrombocytopenic, is related to purpura and hemolytic-uremic syndrome. An important gene associated with Thrombotic Thrombocytopenic Purpura is ADAMTS13 (ADAM metallopeptidase with thrombospondin type 1 motif, 13), and among its related pathways are Translocation of ZAP-70 to Immunological synapse and TCR signaling. The compounds ticlopidine and beraprost sodium have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and brain, and related mouse phenotypes are digestive/alimentary and immune system.

Wikipedia:63 Thrombotic thrombocytopenic purpura (TTP or Moschcowitz syndrome) is a rare disorder of the... more...

Related Diseases for Thrombotic Thrombocytopenic Purpura

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Diseases in the Thrombotic Thrombocytopenic Purpura family:

Thrombotic Thrombocytopenic Purpura, Familial Thrombotic Thrombocytopenic Purpura, Acquired

Diseases related to Thrombotic Thrombocytopenic Purpura via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 192)
idRelated DiseaseScoreTop Affiliating Genes
1purpura33.3ADAMTS13
2hemolytic-uremic syndrome31.8VWF, ADAMTS13, THBD
3systemic lupus erythematosus31.4THBD, VWF, ADAMTS13
4connective tissue disease31.3THBD, VWF
5hemolytic anemia31.3ADAMTS13, VWF
6hellp syndrome31.3ADAMTS13, VWF
7thrombocytopenia31.0VWF, THBD, ADAMTS13, WAS
8lupus nephritis30.9THBD, ADAMTS13
9thrombotic thrombocytopenic purpura, acquired30.9VWF, THBD, THBS1, ADAMTS13
10antiphospholipid syndrome30.9VWF, ADAMTS13, THBD
11disseminated intravascular coagulation30.8ADAMTS13, THBD, SERPINF2
12myocardial infarction30.8SERPINF2, VWF, ADAMTS13
13vasculitis30.7VWF, THBD
14essential thrombocythemia30.7THBD, VWF
15thrombophilia30.2SERPINF2, THBD, VWF
16acute myocardial infarction30.2THBD, SERPINF2, VWF, ADAMTS13
17vascular disease29.8THBS1, THBD, VWF, SERPINF2
18lupus erythematosus10.9
19thrombotic thrombocytopenic purpura, familial10.8
20pancreatitis10.8
21retinitis10.8
22hepatitis10.7
23acute pancreatitis10.7
24mixed connective tissue disease10.7
25adult-onset still's disease10.7
26endotheliitis10.7
27multiple myeloma10.6
28hepatitis c10.6
29myeloma10.6
30retinal detachment10.6
31bone marrow necrosis10.6
32retinal vein occlusion10.6
33central retinal vein occlusion10.6
34influenza10.6
35prostatitis10.6
36prostate cancer10.5
37glomerulonephritis10.5
38leukemia10.5
39hemoglobin c disease10.5
40cerebritis10.5
41adenocarcinoma10.5
42malignant hypertension10.5
43scleroderma10.5
44nephritis10.5
45sickle cell - hemoglobin c disease10.5
46malaria10.4ADAMTS13
47hemolytic uremic syndrome, atypical 110.4
48hemangioma thrombocytopenia syndrome10.4
49hepatitis c virus10.4
50wiskott-aldrich syndrome10.4

Graphical network of the top 20 diseases related to Thrombotic Thrombocytopenic Purpura:



Diseases related to thrombotic thrombocytopenic purpura

Symptoms for Thrombotic Thrombocytopenic Purpura

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Drugs & Therapeutics for Thrombotic Thrombocytopenic Purpura

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Drug clinical trials:

Search ClinicalTrials for Thrombotic Thrombocytopenic Purpura

Search NIH Clinical Center for Thrombotic Thrombocytopenic Purpura

Genetic Tests for Thrombotic Thrombocytopenic Purpura

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Anatomical Context for Thrombotic Thrombocytopenic Purpura

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MalaCards organs/tissues related to Thrombotic Thrombocytopenic Purpura:

31
Kidney, Heart, Brain, Liver, Bone marrow, Bone, Endothelial, Testes, B cells, Lung, Prostate, Retina, Breast, Cortex, Colon, Pancreas, Pancreatic islet, Pituitary, Neutrophil

Animal Models for Thrombotic Thrombocytopenic Purpura or affiliated genes

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MGI Mouse Phenotypes related to Thrombotic Thrombocytopenic Purpura:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.1VWF, THBD, THBS1, WAS
2MP:00053878.0ADAMTS13, WAS, THBS1, THBD, VWF
3MP:00053977.9VWF, THBD, THBS1, WAS, ADAMTS13
4MP:00053767.2ADAMTS13, WAS, SERPINF2, THBS1, THBD, VWF

Publications for Thrombotic Thrombocytopenic Purpura

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Articles related to Thrombotic Thrombocytopenic Purpura:

(show top 50)    (show all 749)
idTitleAuthorsYear
1
Current insights into thrombotic microangiopathies: Thrombotic thrombocytopenic purpura and pregnancy. (25903530)
2015
2
Thrombotic thrombocytopenic purpura and other thrombotic microangiopathic hemolytic anemias: Diagnosis and classification. (24418304)
2014
3
The spleen-derived autoimmune response to ADAMTS13 in Thrombotic Thrombocytopenic Purpura contains recurrent antigen-binding CDR3 motifs. (25261198)
2014
4
Thrombotic thrombocytopenic purpura in children. (23422353)
2013
5
Post-cardiac surgery thrombotic thrombocytopenic purpura with digital ischaemia. (23659403)
2013
6
Acquired thrombotic thrombocytopenic purpura (TTP) induced by silicone breast implants in 37-year old woman. (23477708)
2013
7
Multiple in silico tools predict phenotypic manifestations in congenital thrombotic thrombocytopenic purpura. (23346910)
2013
8
Treatment of refractory thrombotic thrombocytopenic purpura with N-acetylcysteine: a case report. (24117464)
2013
9
Thrombotic thrombocytopenic purpura (TTP)-like illness associated with intravenous Opana ER abuse--Tennessee, 2012. (23302815)
2013
10
Inherited thrombotic thrombocytopenic purpura in pregnancy. (24378452)
2013
11
Long term outcome and sequelae in patients after acute thrombotic thrombocytopenic purpura episodes. (23599034)
2013
12
Drop of residual plasmatic activity of ADAMTS13 to undetectable levels during acute disease in a patient with adult-onset congenital thrombotic thrombocytopenic purpura. (22981442)
2013
13
Inverse correlation of free and immune complex-sequestered anti-ADAMTS13 antibodies in a patient with acquired thrombotic thrombocytopenic purpura. (22044668)
2012
14
Management of Thrombotic Thrombocytopenic Purpura with Autoantibodies to ADAMTS-13 and Concurrent Preeclampsia in Pregnancy: Multidisciplinary Team Approach. (23946903)
2012
15
Thrombotic thrombocytopenic purpura triggered by influenza A virus subtype H1N1 infection. (22094185)
2012
16
Coexistence of systemic lupus erythematosus and thrombotic thrombocytopenic purpura: a case report. (22611780)
2012
17
Transfusion medicine illustrated. Massive hemolysis due to thrombotic thrombocytopenic purpura in a patient with AIDS. (22780894)
2012
18
Advantages and limits of ADAMTS13 testing in the prognostic assessment of thrombotic thrombocytopenic purpura. (22244722)
2012
19
Role of ADAMTS13 in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura. (23233642)
2012
20
Current management and therapeutical perspectives in thrombotic thrombocytopenic purpura. (22265954)
2012
21
Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura. (21535387)
2011
22
Complete recovery of ischemic cardiomyopathy from thrombotic thrombocytopenic purpura. (21487455)
2011
23
Is there a link between thrombotic thrombocytopenic purpura and anti-glomerular basement membrane disease? (21430178)
2011
24
Thrombotic thrombocytopenic purpura associated with disseminated varicella zoster in a multiple myeloma patient. (21260958)
2010
25
Postoperative thrombotic thrombocytopenic purpura after open heart operations. (20103218)
2010
26
Case series: splenectomy: does it still play a role in the management of thrombotic thrombocytopenic purpura? (20858382)
2010
27
High versus standard dose methylprednisolone in the acute phase of idiopathic thrombotic thrombocytopenic purpura: a randomized study. (20033409)
2010
28
Thrombotic thrombocytopenic purpura--the role of ADAMTS13 assay in clinical practice. (20977108)
2010
29
Rituximab as pre-emptive treatment in patients with thrombotic thrombocytopenic purpura and evidence of anti-ADAMTS13 autoantibodies. (19190804)
2009
30
Minor stroke as singular manifestation of hereditary thrombotic thrombocytopenic purpura in a young man. (19648879)
2009
31
Cognitive deficits after recovery from thrombotic thrombocytopenic purpura. (19222817)
2009
32
Brain lesions are most often reversible in acute thrombotic thrombocytopenic purpura. (19564586)
2009
33
Hypersensitivity to plasma exchange in a patient with thrombotic thrombocytopenic purpura. (19073012)
2009
34
Plasma exchange therapy for thrombotic thrombocytopenic purpura in pediatric patients with liver transplantation. (18929799)
2008
35
Synergistic interactions between interferon-gamma and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sensitivity to thrombotic thrombocytopenic purpura plasma-associated apoptosis. (18339897)
2008
36
Treatment of acquired thrombotic thrombocytopenic purpura (TTP) with plasma infusion plus rituximab. (18612551)
2008
37
Thrombotic thrombocytopenic purpura associated with severe acute pancreatitis in a context of decreased ADAMTS13 activity: a case report. (18989146)
2008
38
Congenital thrombotic thrombocytopenic purpura: Lessons for recognition and management of rare syndromes. (18360884)
2008
39
Pancreatitis preceding acute episodes of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: report of five patients with a systematic review of published reports. (17606444)
2007
40
ADAMTS13-binding IgG are present in patients with thrombotic thrombocytopenic purpura. (16676082)
2006
41
Thrombotic thrombocytopenic purpura. (16102032)
2005
42
Clinical features and laboratory findings of thrombotic thrombocytopenic purpura associated with ticlopidine]. (16104532)
2005
43
ADAMTS13, thrombotic thrombocytopenic purpura, and hemolytic uremic syndrome. (15865866)
2005
44
Thrombotic thrombocytopenic purpura complicating SjAPgren's syndrome with crescentic glomerulonephritis and membranous nephritis. (17143670)
2004
45
ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. (12637323)
2003
46
Acquired protein S deficiency in thrombotic thrombocytopenic purpura patients receiving solvent/detergent plasma exchange. (12877681)
2003
47
An update on the pathogenesis and management of acquired thrombotic thrombocytopenic purpura. (12858075)
2003
48
Schizocytosis in pernicious anemia mimicking thrombotic thrombocytopenic purpura. (12714141)
2003
49
Remission of thrombotic thrombocytopenic purpura in a patient with compound heterozygous deficiency of von Willebrand factor-cleaving protease by infusion of solvent/detergent plasma. (12434890)
2002
50
Thrombotic-thrombocytopenic purpura (Moschcowitz syndrome)]. (11450586)
2001

Variations for Thrombotic Thrombocytopenic Purpura

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Clinvar genetic disease variations for Thrombotic Thrombocytopenic Purpura:

6 (show all 24)
id Gene Variation Type Significance SNP ID Assembly Location
1ADAMTS13NM_139025.4(ADAMTS13): c.286C> G (p.His96Asp)single nucleotide variantPathogenicrs121908467GRCh37Chr 9, 136289554: 136289554
2ADAMTS13NM_139025.4(ADAMTS13): c.2851T> G (p.Cys951Gly)single nucleotide variantPathogenicrs121908468GRCh37Chr 9, 136313839: 136313839
3ADAMTS13NM_139025.4(ADAMTS13): c.304C> T (p.Arg102Cys)single nucleotide variantPathogenicrs121908469GRCh37Chr 9, 136289572: 136289572
4ADAMTS13NM_139025.4(ADAMTS13): c.587C> T (p.Thr196Ile)single nucleotide variantPathogenicrs121908470GRCh37Chr 9, 136291366: 136291366
5ADAMTS13NM_139025.4(ADAMTS13): c.1193G> A (p.Arg398His)single nucleotide variantPathogenicrs121908471GRCh37Chr 9, 136298598: 136298598
6ADAMTS13NM_139025.4(ADAMTS13): c.3070T> G (p.Cys1024Gly)single nucleotide variantPathogenicrs121908472GRCh37Chr 9, 136319562: 136319562
7ADAMTS13NM_139025.4(ADAMTS13): c.1582A> G (p.Arg528Gly)single nucleotide variantPathogenicrs121908473GRCh37Chr 9, 136303015: 136303015
8ADAMTS13ADAMTS13: c.3770dupT (p.Leu1257delinsLeuValfs)duplicationPathogenicrs387906341GRCh37Chr 9, 136321719: 136321720
9ADAMTS13ADAMTS13: c.2376_2401del26 (p.Pro792_Pro801delinsProProfs)deletionPathogenicrs387906342GRCh37Chr 9, 136308638: 136308663
10ADAMTS13ADAMTS13: c.4143_4144insA (p.Ser1381_Glu1382delinsSerArgGlufs)duplicationPathogenicrs387906343GRCh37Chr 9, 136324161: 136324162
11ADAMTS13NM_139025.4(ADAMTS13): c.3638G> A (p.Cys1213Tyr)single nucleotide variantPathogenicrs121908474GRCh37Chr 9, 136321260: 136321260
12ADAMTS13NM_139025.4(ADAMTS13): c.2074C> T (p.Arg692Cys)single nucleotide variantPathogenicrs121908475GRCh37Chr 9, 136307625: 136307625
13ADAMTS13ADAMTS13, IVS13DS, G-A, +5single nucleotide variantPathogenic
14ADAMTS13NM_139025.4(ADAMTS13): c.1345C> T (p.Gln449Ter)single nucleotide variantPathogenicrs121908476GRCh37Chr 9, 136301985: 136301985
15ADAMTS13NM_139025.4(ADAMTS13): c.803G> C (p.Arg268Pro)single nucleotide variantPathogenicrs121908477GRCh37Chr 9, 136293870: 136293870
16ADAMTS13NR_024514.1(ADAMTS13): n.993-2505C> Gsingle nucleotide variantPathogenicrs2301612GRCh37Chr 9, 136301982: 136301982
17ADAMTS13NM_139025.4(ADAMTS13): c.1423C> T (p.Pro475Ser)single nucleotide variantPathogenicrs11575933GRCh37Chr 9, 136302063: 136302063
18ADAMTS13ADAMTS13: c.1783_1784delTT (p.Leu595Glyfs)deletionPathogenicrs387906344GRCh37Chr 9, 136304564: 136304565
19ADAMTS13ADAMTS13, IVS4DS, G-A, +1single nucleotide variantPathogenic
20ADAMTS13NM_139025.4(ADAMTS13): c.749C> T (p.Ala250Val)single nucleotide variantPathogenicrs121908478GRCh37Chr 9, 136293816: 136293816
21ADAMTS13ADAMTS13, IVS3DS, G-Asingle nucleotide variantPathogenic
22ADAMTS13ADAMTS13: c.291_319del29 (p.Gln97_Asn107delinsGlnProfs)deletionPathogenicrs387906345GRCh37Chr 9, 136289559: 136289587
23ADAMTS13ADAMTS13: c.2930_2935delGTGCCC (p.Cys977_Arg979delinsTrp)deletionPathogenicrs387906346GRCh37Chr 9, 136314972: 136314977
24ADAMTS13ADAMTS13: c.1523G> A (p.Cys508Tyr)single nucleotide variantPathogenicrs281875305GRCh37Chr 9, 136302956: 136302956

Expression for genes affiliated with Thrombotic Thrombocytopenic Purpura

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Search GEO for disease gene expression data for Thrombotic Thrombocytopenic Purpura.

Pathways for genes affiliated with Thrombotic Thrombocytopenic Purpura

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Pathways related to Thrombotic Thrombocytopenic Purpura according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5WAS, HLA-DRB4
2
Show member pathways
9.5WAS, HLA-DRB4
3
Show member pathways
Complement Activation, Classical Pathway36
Complement and Coagulation Cascades36
8.7SERPINF2, THBD, VWF
4
Show member pathways
8.7SERPINF2, THBD, VWF
5
Show member pathways
8.6VWF, THBS1, SERPINF2
6
Show member pathways
8.1SERPINF2, THBS1, THBD, VWF

Compounds for genes affiliated with Thrombotic Thrombocytopenic Purpura

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Compounds related to Thrombotic Thrombocytopenic Purpura according to GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idCompoundScoreTop Affiliating Genes
1ticlopidine43 1211.0ADAMTS13, VWF
2beraprost sodium439.9VWF, THBD
311-dehydrothromboxane b2439.9THBD, VWF
4lm 609439.9VWF, THBS1
5perindopril43 49 1211.8THBD, VWF
6paricalcitol43 1210.7THBS1, THBD
7fitc439.7THBD, VWF
8cacl2439.6THBD, THBS1
9dermatan sulfate439.6THBD, VWF
10fluvastatin43 49 28 1212.5THBD, VWF
11fibrinopeptide a439.5SERPINF2, THBD
12ptca439.4THBD, SERPINF2
13raloxifene43 49 28 1212.3THBD, VWF, THBS1
14latex439.3VWF, THBS1, WAS
15n-formylmethionyl-leucylphenylalanine439.3THBD, THBS1
16atorvastatin43 49 28 24 1213.3THBD, THBS1, VWF
17epsilon aminocaproic acid439.3SERPINF2, THBS1
18cytochalasin d43 5910.3WAS, VWF, THBS1
19agarose439.3VWF, THBS1, THBD
20ristocetin439.3SERPINF2, ADAMTS13, VWF
21hyaluronic acid43 2410.3VWF, THBD, THBS1
22prostacyclin439.3VWF, THBD, THBS1
23phosphatidylserine43 28 1211.3THBS1, THBD, VWF
24warfarin43 49 24 1212.2THBD, VWF
25matrigel439.2VWF, THBD, THBS1
266-ketoprostaglandin f1alpha439.2SERPINF2, THBD, VWF
27methionine439.2THBS1, THBD, VWF
28thromboxane43 2410.1THBD, SERPINF2, VWF
29aprotinin43 1210.1SERPINF2, THBD, VWF
30endotoxin439.1ADAMTS13, SERPINF2, THBD
31thyroxine43 2410.1VWF, THBD, SERPINF2
32creatinine439.1VWF, ADAMTS13, THBD
33paraffin439.1VWF, THBS1, THBD
34cyclophosphamide43 49 1211.0ADAMTS13, VWF, THBS1, THBD
35cyclosporin a43 28 5911.0ADAMTS13, VWF, THBS1, THBD
36heparan sulfate43 249.9THBD, THBS1, SERPINF2
37desmopressin43 59 28 1211.8THBD, ADAMTS13, SERPINF2, VWF
38polysaccharide438.7THBD, THBS1, SERPINF2
39hirudin438.6THBS1, VWF, THBD, SERPINF2
40txb2438.5SERPINF2, VWF, THBD, THBS1
41kininogen438.5THBD, SERPINF2, THBS1, VWF
42adp43 28 2410.5SERPINF2, WAS, THBD, VWF
43cholesterol43 28 24 1211.5SERPINF2, VWF, THBD, THBS1
44vegf438.4VWF, THBD, THBS1, SERPINF2
45alanine438.4VWF, SERPINF2, THBS1, THBD
46fibrinogen438.2THBS1, VWF, SERPINF2, THBD, ADAMTS13
47heparin43 28 24 1211.2THBD, ADAMTS13, SERPINF2, THBS1, VWF
48lipid438.1THBD, THBS1, SERPINF2, WAS
49calcium43 49 24 1210.9THBS1, SERPINF2, VWF, WAS, ADAMTS13
50serine437.6THBS1, VWF, THBD, SERPINF2, WAS, ADAMTS13

GO Terms for genes affiliated with Thrombotic Thrombocytopenic Purpura

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Cellular components related to Thrombotic Thrombocytopenic Purpura according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granuleGO:00310919.3VWF, THBS1
2fibrinogen complexGO:00055779.0SERPINF2, THBS1
3platelet alpha granule lumenGO:00310938.7VWF, THBS1, SERPINF2
4external side of plasma membraneGO:00098978.7THBS1, HLA-DRB4, VWF
5cell surfaceGO:00099868.2THBD, THBS1, SERPINF2, ADAMTS13
6extracellular spaceGO:00056158.1THBS1, THBD, ADAMTS13, SERPINF2

Biological processes related to Thrombotic Thrombocytopenic Purpura according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1T cell receptor signaling pathwayGO:00508529.5HLA-DRB4, WAS
2negative regulation of plasminogen activationGO:00107578.9THBS1, SERPINF2
3negative regulation of fibrinolysisGO:00519188.7THBD, THBS1, SERPINF2
4platelet degranulationGO:00025768.6SERPINF2, THBS1, VWF
5immune responseGO:00069558.6WAS, HLA-DRB4, THBS1
6platelet activationGO:00301688.3SERPINF2, THBS1, VWF, ADAMTS13
7blood coagulationGO:00075967.7VWF, THBD, THBS1, SERPINF2, WAS

Molecular functions related to Thrombotic Thrombocytopenic Purpura according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glycoprotein bindingGO:00019489.4THBS1, VWF
2integrin bindingGO:00051789.2THBS1, VWF, ADAMTS13
3calcium ion bindingGO:00055099.0THBD, THBS1, ADAMTS13
4protease bindingGO:00020208.9VWF, SERPINF2
5identical protein bindingGO:00428028.8WAS, THBS1, VWF
6protein bindingGO:00055156.8SERPINF2, HLA-DRB4, ADAMTS13, THBS1, THBD, VWF

Products for genes affiliated with Thrombotic Thrombocytopenic Purpura

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Sources for Thrombotic Thrombocytopenic Purpura

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet