MCID: THY043
MIFTS: 32

Thymic Hyperplasia malady

Categories: Rare diseases, Endocrine diseases

Aliases & Classifications for Thymic Hyperplasia

About this section

Aliases & Descriptions for Thymic Hyperplasia:

Name: Thymic Hyperplasia 45
Hyperplasia of Thymus Gland 45
 
Thymus Hyperplasia 65

Classifications:



External Ids:

UMLS65 C0040115

Summaries for Thymic Hyperplasia

About this section
MalaCards based summary: Thymic Hyperplasia, also known as hyperplasia of thymus gland, is related to hepatitis and leukemia. An important gene associated with Thymic Hyperplasia is AKTIP (AKT Interacting Protein), and among its related pathways are amb2 Integrin signaling and Advanced glycosylation endproduct receptor signaling. Affiliated tissues include thymus, bone and prostate, and related mouse phenotypes are other and limbs/digits/tail.

Related Diseases for Thymic Hyperplasia

About this section

Graphical network of the top 20 diseases related to Thymic Hyperplasia:



Diseases related to thymic hyperplasia

Symptoms for Thymic Hyperplasia

About this section

Drugs & Therapeutics for Thymic Hyperplasia

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Role of the Thymus in Myasthenia GravisActive, not recruitingNCT01102192

Search NIH Clinical Center for Thymic Hyperplasia

Genetic Tests for Thymic Hyperplasia

About this section

Anatomical Context for Thymic Hyperplasia

About this section

MalaCards organs/tissues related to Thymic Hyperplasia:

33
Thymus, Bone, Prostate, Breast, T cells, Colon, Testes

Animal Models for Thymic Hyperplasia or affiliated genes

About this section

MGI Mouse Phenotypes related to Thymic Hyperplasia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.8RPE65, TSHR, XIAP
2MP:00053719.0AKTIP, TP63, TSHR, XIAP
3MP:00053867.4AGER, AKTIP, PTTG1, RPE65, TP63, TSHR

Publications for Thymic Hyperplasia

About this section

Articles related to Thymic Hyperplasia:

(show top 50)    (show all 181)
idTitleAuthorsYear
1
Synergistic effect of factor VII gene polymorphisms causing mild factor VII deficiency in a case of severe factor X deficiency. (26919454)
2016
2
Left ventricular noncompaction and athletes: looking for stratification criteria. (25560945)
2015
3
Prolactin and prolactin receptor expression in cervical intraepithelial neoplasia and cancer. (24990775)
2015
4
Association of polymorphisms in glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) with idiopathic azoospermia or oligospermia in Sichuan, China. (25532576)
2014
5
Fulminans in dermatology: a call to action: a recommendation for consideration of the term scleredema fulminans. (25013539)
2014
6
Sudden extramedullary blast crisis of chronic myeloid leukemia manifesting as T-cell lymphoblastic lymphoma. (23486000)
2013
7
Somnolence upon allergen provocation in a child with Hen's egg allergy. (23519753)
2013
8
Laparoscopic management of right renal angiomyolipoma with involvement of the inferior vena cava: case report and review of the literature. (23206184)
2013
9
Hetastarch-induced osmotic nephrosis. (22370625)
2012
10
A surgically treated case of chronic necrotizing aspergillosis with pleural invasion. (22363911)
2012
11
Effect of smoking and gender on pulmonary function and clinical features in sarcoidosis. (22773249)
2012
12
High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE. (23067351)
2012
13
Peritumoral p53 expression in oral carcinoma. (23397771)
2012
14
Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. (21255211)
2011
15
Late recovery with cyclosporine-A of an auto-immune sudden sensorineural hearing loss. (22323852)
2011
16
Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection. (21760719)
2011
17
Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis. (21239750)
2011
18
Childhood optic neuritis clinical features and outcome. (20554767)
2011
19
Tetracycline treatment in patients with progressive external ophthalmoplegia. (21649612)
2011
20
Inhibition of PKHD1 may cause S-phase entry via mTOR signaling pathway. (19524688)
2009
21
The control and surveillance of filariasis in Hainan Province, China. (18567440)
2008
22
Treatment of argyria after colloidal silver ingestion using Q-switched 1,064-nm Nd:YAG laser. (18657163)
2008
23
Perioperative management of a patient with Bernard-Soulier syndrome for third molar surgery. (17174124)
2007
24
Traditional methods for the treatment of presbyopia: spectacles, contact lenses, bifocal contact lenses. (16500526)
2006
25
Chemopreventive effect of protein extract of Asterina pectinifera in HT-29 human colon adenocarcinoma cells. (16596993)
2006
26
Short-term motor and sensory outcomes in acquired nonaccommodative esotropia of childhood. (16251139)
2005
27
Lactic acid still remains the real cause of exercise-induced metabolic acidosis. (16105825)
2005
28
Effects of CD147 on the production of matrix metalloproteinase-9 by fibroblasts and the invasion of melanoma cells]. (16045006)
2005
29
Prostate cancer in patients with screening serum prostate specific antigen values less than 4.0 ng/dl: results from the cooperative prostate cancer tissue resource. (15821483)
2005
30
Histone deacetylase inhibition and estrogen signalling in human breast cancer cells. (15313422)
2004
31
Pharmacokinetic/pharmacodynamic modelling of effects of dexamethasone and prednisolone in combination with endogenous cortisol on lymphocyte counts and systemic markers of bone turn over and inflammation in healthy and asthmatic men. (15150679)
2004
32
Therapeutic implications of epidermal growth factor receptor in lung cancer]. (14763145)
2003
33
Vitamin D receptor gene polymorphism in familial prostate cancer in a Japanese population. (12694466)
2003
34
Early growth-responsive-1-dependent manganese superoxide dismutase gene transcription mediated by platelet-derived growth factor. (11511524)
2001
35
Interleukin-1beta induces cyclooxygenase-2 and prostaglandin E(2) synthesis in human neuroblastoma cells: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB. (11032891)
2000
36
Study of gastrointestinal polypeptides controlling gastric acid secretion in patients with primary antibody deficiency. (10089787)
1999
37
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and risk of urothelial transitional cell carcinoma among Japanese. (10471074)
1999
38
Differentiating juvenile myelomonocytic leukemia from infectious disease. (9414312)
1998
39
Bone metabolism following bladder substitution with the ileal urethral Kock reservoir. (9117211)
1997
40
The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA. (9038151)
1997
41
CD4 lymphopenia in elderly patients. (8622438)
1996
42
Karyotypic evolution in a granulocytic sarcoma developing in a myeloproliferative disorder with a novel (3;4) translocation. (7794773)
1995
43
Case report 696: Chondroblastoma of the right acetabulum and superior pubic ramus. (1754919)
1991
44
Membrane lateral pressure as a modulator of glycerol-3-phosphate dehydrogenase activity. (2226800)
1990
45
Bacillary dysentery. (6386299)
1984
46
Many misjudge severity of orbital cellulitis. (7062533)
1982
47
Septicaemia in kwashiorkor. (349714)
1978
48
Peripheral dysostosis associated with juvenile nephronophthisis. (1182437)
1975
49
Steroid 17,20-desmolase deficiency: a new cause of male pseudohermaphroditism. (4352099)
1972
50
FUSION AMPLITUDE WITH ABNORMAL RETINAL CORRESPONDENCE? (18170757)
1962

Variations for Thymic Hyperplasia

About this section

Expression for genes affiliated with Thymic Hyperplasia

About this section
Search GEO for disease gene expression data for Thymic Hyperplasia.

Pathways for genes affiliated with Thymic Hyperplasia

About this section

Pathways related to Thymic Hyperplasia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5AGER, HMGB1
29.5AGER, HMGB1

GO Terms for genes affiliated with Thymic Hyperplasia

About this section

Biological processes related to Thymic Hyperplasia according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-12 productionGO:003273510.0AGER, HMGB1
2positive regulation of activated T cell proliferationGO:00421049.9AGER, HMGB1
3positive regulation of JNK cascadeGO:00463309.7CCL21, HMGB1
4dendritic cell chemotaxisGO:00024079.6CCL21, HMGB1
5activation of GTPase activityGO:00906309.6CCL21, CXCL13
6positive regulation of protein phosphorylationGO:00019349.5AGER, HMGB1
7chemokine-mediated signaling pathwayGO:00700989.3CCL21, CXCL13
8apoptotic processGO:00069158.7AKTIP, HMGB1, TP63, XIAP

Sources for Thymic Hyperplasia

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet