MCID: THY009
MIFTS: 53

Thyroid Lymphoma malady

Blood diseases, Cancer diseases, Rare diseases, Immune diseases categories

Summaries for Thyroid Lymphoma

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Wikipedia:64 Thyroid lymphoma is a rare malignant tumor constituting 1% to 2% of all thyroid malignancies and less... more...

MalaCards based summary: Thyroid Lymphoma is related to colitis and b-cell lymphomas. An important gene associated with Thyroid Lymphoma is CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)), and among its related pathways are IL-7 Signaling and its Primary Biological Effects in Different Immune Cell Types and 14-3-3 and Regulation of BAD Activity. The compounds depsipeptide and noxa have been mentioned in the context of this disorder. Affiliated tissues include thyroid, b cells and colon, and related mouse phenotypes are pigmentation and vision/eye.

Aliases & Classifications for Thyroid Lymphoma

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Thyroid Lymphoma, Aliases & Descriptions:

Name: Thyroid Lymphoma 9 11 48 61


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Blood diseases, Immune diseases


External Ids:

Disease Ontology9 DOID:10011
NCIt39 C5265

Related Diseases for Thyroid Lymphoma

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Diseases related to Thyroid Lymphoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 92)
idRelated DiseaseScoreTop Affiliating Genes
1colitis30.0IL7R, IL7, TNF
2b-cell lymphomas29.1TP53, FAS, FOXP1, CCNA2, CCNB1, BCL2
3leukemia27.6PICALM, BCL2, MAPK1, IL7R, IL7, CCNB1
4thyroiditis11.1
5actinic keratosis10.4TP53
6meningioma10.4CDKN2B, TP73
7lymphopenia10.3IL7R, IL7, FAS
8anaplastic oligodendroglioma10.3CDKN2B, CDKN2A
9gamma chain deficiency10.3IL7, IL7R
10neuroblastoma10.3TP53
11cutaneous t cell lymphoma10.2CDKN2B, IL7R, IL7, FAS
12colon cancer10.2
13oropharyngeal cancer, adult10.2CDKN2A, TP53
14burkitt's lymphoma10.2TP73, BCL2, CDKN2B
15acute leukemia10.2CCNA2, CCNB1, IL7, CDKN2B
16cervical intraepithelial neoplasia10.2CDKN2A, CDK1, TP73
17bladder transitional cell carcinoma10.2CDKN2B, TP53
18acute lymphoblastic leukemia, childhood10.2CCNA2, IL7, CDKN2A, CDKN2B
19leukemia, acute lymphoblastic 310.2TP73, IL7, CDKN2A, CDKN2B
20li-fraumeni syndrome10.2TP53, CDKN2A
21nasopharynx carcinoma10.2CDKN2A, TP53
22human immunodeficiency virus infectious disease10.1IL7R, IL7
23subacute thyroiditis10.1
24goiter10.1
25hyperthyroidism10.1
26kidney cancer10.1TP73, FAS, CCNB1, IL7
27colon adenocarcinoma10.1BCL2, CCNA2, FAS
28hematologic cancer10.1PICALM, TP73, CCNA2, IL7, CDKN2B
29medulloblastoma10.1TP53, TP73, CDKN2B
30bladder carcinoma10.1TP53, CCNA2, CDKN2A
31brain cancer10.1TP53, TP73, CCNB1, CDKN2B
32glioblastoma multiforme10.1CDKN2B, CDKN2A, CCNA2, TP53
33oligodendroglioma10.0TP53, TP73, CDKN2A, CDKN2B
34esophageal cancer10.0CDKN2B, CDKN2A, TP73, TP53
35papilloma10.0TP53, TP73, CDKN2A, CDKN2B
36graft versus host disease10.0TNF, FAS, IL7
37basal cell carcinoma10.0BCL2, CCNB1, TP53
38chronic lymphocytic leukemia10.0CCNA2, IL7, BCL2, CDK1, CDKN2B
39endometrial carcinoma10.0TP53, TP73, CCNB1, CDKN2A
40adult t-cell leukemia10.0
41diffuse large b-cell lymphoma10.0
42ulcerative colitis10.0
43multinodular goiter10.0
44graves' disease10.0
45cerebritis10.0
46hypothyroidism10.0
47laryngitis10.0
48papillary thyroid carcinoma10.0
49sarcoidosis10.0
50t-cell leukemia10.0

Graphical network of the top 20 diseases related to Thyroid Lymphoma:



Diseases related to thyroid lymphoma

Symptoms for Thyroid Lymphoma

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Drugs & Therapeutics for Thyroid Lymphoma

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Drug clinical trials:

Search ClinicalTrials for Thyroid Lymphoma

Search NIH Clinical Center for Thyroid Lymphoma

Genetic Tests for Thyroid Lymphoma

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Anatomical Context for Thyroid Lymphoma

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MalaCards organs/tissues related to Thyroid Lymphoma:

32
Thyroid, B cells, Colon, T cells

Animal Models for Thyroid Lymphoma or affiliated genes

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MGI Mouse Phenotypes related to Thyroid Lymphoma:

36 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.1TP53, FAS, BCL2, CDKN2A
2MP:00053918.7TNF, TP53, TP73, FAS, BCL2, CDKN2A
3MP:00053818.5TNF, TP53, TP73, FAS, FOXP1, BCL2
4MP:00053698.4TNF, TP53, FOXP1, MAPK1, BCL2, CDKN2A
5MP:00107718.4TNF, TP53, FAS, MAPK1, BCL2, CDKN2A
6MP:00053888.2TNF, TP53, TP73, FAS, FOXP1, MAPK1
7MP:00053828.2TNF, TP53, TP73, FAS, SSBP3, BCL2
8MP:00053708.2PICALM, TNF, TP53, FAS, MAPK1, CDK1
9MP:00053908.1CDKN2A, SSBP3, FAS, TP73, TP53, TNF
10MP:00053798.0TNF, TP53, TP73, FAS, BCL2, CDK1
11MP:00053857.9TNF, TP53, TP73, FAS, FOXP1, MAPK1
12MP:00020067.7TNF, TP53, TP73, FAS, MAPK1, BCL2
13MP:00053897.7TNF, TP53, TP73, FAS, MAPK1, BCL2
14MP:00053767.1PICALM, TNF, TP53, TP73, FAS, FOXP1
15MP:00036317.1EBF3, TNF, TP53, TP73, FAS, SSBP3
16MP:00053787.1PICALM, TNF, TP53, TP73, FAS, SSBP3
17MP:00053977.0CDKN2B, PICALM, TNF, TP53, TP73, FAS
18MP:00053877.0FOXP1, FAS, TP73, TP53, TNF, PICALM
19MP:00053806.9PICALM, TNF, TP53, TP73, SSBP3, FOXP1
20MP:00053846.6FOXP1, FAS, TP73, TP53, TNF, PICALM
21MP:00107685.1FAS, TP73, TP53, TNF, EBF3, PICALM

Publications for Thyroid Lymphoma

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Articles related to Thyroid Lymphoma:

(show top 50)    (show all 160)
idTitleAuthorsYear
1
Identification of primary thyroid lymphoma with medical imaging: A case report and review of the literature. (25364417)
2014
2
Primary thyroid lymphoma. (24935697)
2014
3
Ulcerative colitis associated with extranodal marginal zone B-cell thyroid lymphoma of mucosa-associated lymphoid tissue and Hashimoto thyroiditis: description of a case. (24714310)
2013
4
A rare coexistence of thyroid lymphoma with papillary thyroid carcinoma. (24005594)
2013
5
Patterns of care and treatment outcomes for primary thyroid lymphoma: a single institution study. (24501704)
2013
6
Is 18F-FDG PET/CT useful for distinguishing between primary thyroid lymphoma and chronic thyroiditis? (23816945)
2013
7
Thyroid lymphoma incidentally detected by 18F-fluorocholine (FCH) PET/CT. (23856826)
2013
8
Importance of core biopsy in the diagnosis of thyroid lymphoma. (22507512)
2012
9
Primary mucosa-associated lymphoid tissue thyroid lymphoma: a rare thyroid neoplasm of extrathyroid origin. (22532918)
2012
10
Fluorodeoxyglucose positron emission tomography in primary thyroid lymphoma with coexisting lymphocytic thyroiditis. (21875367)
2011
11
Untreated primary thyroid lymphoma in an elderly woman. (21727773)
2011
12
A case of anaplastic diffuse large B-cell thyroid lymphoma: unique immunophenotype and unusual clinical presentation. (21178391)
2010
13
Primary thyroid lymphoma (correction of lympoma): diagnostic and therapeutic dilemmas. (20620043)
2010
14
Thyroid Lymphoma as a Cause of Dysphagia and Dyspnea in a Patient without Palpable Nodules or Goiter. (19841755)
2009
15
Surgical treatment of primitive thyroid lymphoma. (20210235)
2009
16
Thyroid lymphoma: a rare tumor requiring combined management. (19671521)
2009
17
Thyroid lymphoma: beyond antigen stimulation. (19128828)
2009
18
Surgical trends in the management of thyroid lymphoma. (17604588)
2008
19
Thyroid lymphoma: early clinical suspicion may be critical for cure. (18852536)
2008
20
An evidence-based approach to the treatment of thyroid lymphoma. (17235456)
2007
21
FDG PET/CT for assessing therapy response in primary thyroid lymphoma. (17242576)
2007
22
High incidence of mucosa-associated lymphoid tissue in primary thyroid lymphoma: a clinicopathologic study of 18 cases in the Korean population. (17071486)
2006
23
Primary thyroid lymphoma mimicking subacute thyroiditis. (17152291)
2006
24
Anaplastic thyroid carcinoma, thyroid lymphoma, and metastasis to thyroid. (16882503)
2006
25
Anaplastic thyroid cancer and primary thyroid lymphoma: a review of these rare thyroid malignancies. (17131397)
2006
26
Fine needle aspiration cytology of primary thyroid lymphoma: a report of ten cases. (16336672)
2005
27
The incidence of primary thyroid lymphoma in thyroid malignancies. (16010091)
2004
28
Mucosa-associated lymphoid tissue thyroid lymphoma: a rare and not aggressive tumour. (12666700)
2002
29
Primary thyroid lymphoma is a heterogeneous disease. (11788631)
2002
30
Two unusual sites of colon cancer metastases and a rare thyroid lymphoma. Case 2. Chemotherapy-responsive right artial metastasis from colon carcinoma. (11481366)
2001
31
Frequent mutations of Fas gene in thyroid lymphoma. (11245438)
2001
32
A reassessment of primary thyroid lymphoma: high-grade MALT-type lymphoma as a distinct subtype of diffuse large B-cell lymphoma. (10931213)
2000
33
Down's syndrome with mucosa-associated lymphoid tissue, thyroid lymphoma and cerebral infarction. (10746421)
2000
34
Expression of interleukin-7 and its receptor in thyroid lymphoma. (11045564)
2000
35
Primary thyroid lymphoma. (10375088)
1999
36
Acute airway obstruction due to primary thyroid lymphoma. (9102733)
1996
37
Lethal tracheal dissolution during treatment for thyroid lymphoma. (7491567)
1995
38
Immunohistochemical detection of p53 and Bcl-2 proteins in Hashimoto's thyroiditis and primary thyroid lymphomas. (7730485)
1995
39
Thyroid lymphoma. The case for combined modality therapy. (8275426)
1994
40
Primary thyroid lymphoma: clinical features, treatment and outcome: a report of 8 cases. (8052462)
1994
41
The significance of MALT histology in thyroid lymphoma: a review of patients from the BNLI and Royal Marsden Hospital. (7826922)
1994
42
Monoclonal gammopathy as a clue to the presence of thyroid lymphoma associated with auto-immune thyroiditis. (1445050)
1992
43
MR imaging in patients with primary thyroid lymphoma. (1636536)
1992
44
Hashimoto's thyroiditis as a risk factor of thyroid lymphoma. (2220394)
1990
45
Hashimoto's disease, thyroid lymphoma and splenic atrophy. (2484910)
1989
46
Thyroid lymphoma. (2804581)
1989
47
MR imaging of primary thyroid lymphoma. (2723189)
1989
48
Laryngeal oedema complicating thyroid lymphoma. (3199019)
1988
49
Ultrasonography in the diagnosis of thyroid lymphoma. (3910657)
1985
50
Thyroid lymphoma in a patient with hyperthyroidism. (6702880)
1984

Variations for Thyroid Lymphoma

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Expression for genes affiliated with Thyroid Lymphoma

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Expression patterns in normal tissues for genes affiliated with Thyroid Lymphoma

Search GEO for disease gene expression data for Thyroid Lymphoma.

Pathways for genes affiliated with Thyroid Lymphoma

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Pathways related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 100)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7IL7R, IL7, BCL2
29.5TP73, BCL2, TNF
3
Show member pathways
9.5FAS, BCL2, TNF
49.4BCL2, MAPK1, TNF
59.3CCNA2, TP53, CCNB1
6
Show member pathways
ATM Signaling Pathway37
9.3CCNB1, TP53, TP73
79.2TP53, MAPK1, CDKN2B, CDKN2A
8
Show member pathways
9.2CDKN2A, TP73, TP53, BCL2
9
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation59
9.2CDKN2B, CDK1, CCNA2, CDKN2A
10
Show member pathways
Apoptosis and survival Apoptotic TNF family pathways59
9.1BCL2, FAS, TNF, TP53
119.1CDKN2A, TP53, MAPK1, BCL2
12
Show member pathways
9.1CCNB1, CCNA2, CDK1
139.1CCNA2, CCNB1, CDK1
14
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes59
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway59
9.1TNF, CCNA2, IL7, IL7R, MAPK1
15
Show member pathways
Alzheimers Disease37
9.1TNF, TP53, FAS, MAPK1
16
Show member pathways
9.1IL7, CDK1, MAPK1, IL7R
17
Show member pathways
9.0CDKN2A, TP53, CCNA2, MAPK1, CDKN2B
189.0TP53, IL7, MAPK1, IL7R, BCL2
19
Show member pathways
8.9CDK1, TP53, CCNB1
20
Show member pathways
Signaling Pathways in Glioblastoma37
8.9BCL2, CDKN2A, MAPK1, TP53, CDKN2B
21
Show member pathways
8.8TP53, CCNA2, CCNB1, CDKN2A, CDKN2B
228.8BCL2, MAPK1, FOXP1, CDKN2A, TP53
23
Show member pathways
Prostate Cancer37
Integrated Cancer pathway37
Steroid Biosynthesis37
8.8BCL2, CDK1, TP53, MAPK1
24
Show member pathways
Apoptosis and survival TNFR1 signaling pathway59
TWEAK Signaling Pathway37
Apoptosis Modulation by HSP7037
HIV-1 Nef- Negative effector of Fas and TNF-alpha37
8.8FAS, MAPK1, TNF, TP53, BCL2
25
Show member pathways
8.8FAS, TNF, TP53, MAPK1, BCL2
26
Show member pathways
8.8MAPK1, FAS, TP53, TNF, BCL2
27
Show member pathways
Cell cycle ESR1 regulation of G1 S transition59
Immune response MIF JAB1 signaling59
Cell cycle Cell cycle generic schema 59
8.8CCNB1, MAPK1, CDK1, CCNA2
28
Show member pathways
8.8CCNA2, CCNB1, MAPK1, CDK1
29
Show member pathways
PLK2 and PLK4 events37
Polo-like kinase signaling events in the cell cycle37
8.8CCNG2, CDKN2B, MAPK1, IL7R, CCNB1
308.7TP53, TP73, CCNB1, FAS, BCL2
318.7MAPK1, CDK1, TNF, TP53
328.7TP53, CDK1, CCNB1, CCNA2
338.7TP53, MAPK1, FAS, CDKN2B, CDKN2A, BCL2
34
Show member pathways
8.6BCL2, MAPK1, IL7R, IL7, TP53, TNF
35
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
8.6BCL2, TNF, TP53, TP73, FAS, CDKN2A
36
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
8.6MAPK1, BCL2, CCNA2, TP53, TNF, FAS
37
Show member pathways
DNA damage response (only ATM dependent)37
Wnt Signaling Pathway and Pluripotency37
8.4TP53, TP73, MAPK1, BCL2, CCNG2, CDKN2A
388.4CDK1, MAPK1, CCNA2, CDKN2B, TP53, CDKN2A
398.4CDKN2B, FAS, BCL2, MAPK1, CCNA2, TNF
40
Show member pathways
8.3TP53, FAS, IL7, BCL2, MAPK1, TNF
41
Show member pathways
Development EGFR signaling via PIP359
Development PDGF signaling via MAPK cascades59
Apoptosis and survival Anti apoptotic action of membrane bound ESR159
Signaling of Hepatocyte Growth Factor Receptor37
Development EGFR signaling via small GTPases59
Development Neurotrophin family signaling59
Apoptosis and survival NGF signaling pathway59
Apoptosis and survival Role of CDK5 in neuronal death and survival59
8.3TP53, FAS, CDK1, TP73, BCL2, MAPK1
42
Show member pathways
8.2TP53, CDK1, MAPK1, FAS, TNF, TP73
43
Show member pathways
Cell cycle37
8.2CDKN2A, CDK1, CDKN2B, CCNB1, CCNA2, TP53
44
Show member pathways
8.2CCNA2, CCNB1, MAPK1, BCL2, CDKN2A, CDKN2B
45
Show member pathways
8.2CCNB1, CDK1, CCNA2, TP73, TP53, CDKN2A
46
Show member pathways
8.1BCL2, IL7, TNF, TP53, IL7R, CDKN2B
47
Show member pathways
7.9TP53, CDKN2B, CDKN2A, CCNB1, MAPK1, CCNA2
48
Show member pathways
7.8CDKN2B, TP53, CCNA2, CCNB1, CCNG2, CDK1
49
Show member pathways
Proteasome Degradation37
Immune response Antigen presentation by MHC class I59
7.8TNF, TP53, CCNB1, BCL2, CDK1, FAS
50
Show member pathways
DNA damage response37
7.7CCNG2, CDK1, CDKN2A, FAS, TP53, CCNB1

Compounds for genes affiliated with Thyroid Lymphoma

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Compounds related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 151)
idCompoundScoreTop Affiliating Genes
1depsipeptide449.3FAS, CCNA2, BCL2, CDKN2A, TP53
2noxa449.2BCL2, FAS, TP73, TP53
3o6-methylguanine449.2CDKN2B, TP73, TP53, CDKN2A
4sulforaphane449.1MAPK1, FAS, BCL2, CCNA2, CCNB1
5c2ceramide448.9TP53, TNF, BCL2, MAPK1, FAS
6flavopiridol44 129.9CDKN2A, CDK1, BCL2, CCNA2, TP53
7vincristine44 50 1210.8BCL2, TP53, CDKN2A, CCNA2, CCNB1, TP73
8egcg448.8TNF, CDKN2A, BCL2, MAPK1, FAS, TP53
9thymidylate448.7FAS, CCNA2, TP53, CDK1, BCL2, CDKN2A
10cytarabine44 50 1210.6TP53, BCL2, FAS, CDKN2B, CDKN2A, CCNA2
11ceramide448.5CDK1, MAPK1, CCNA2, FAS, TNF, BCL2
12hydroxyurea44 50 1210.5TP53, CCNB1, CDKN2A, CCNA2, CDK1
13vinblastine44 50 1210.5CCNB1, CDK1, BCL2, CCNA2, TP53
145fluorouracil448.5BCL2, TP53, TP73, FAS, CCNA2, CDK1
15actinomycin d448.5BCL2, TP53, MAPK1, CDKN2A, FAS, TNF
16docetaxel44 50 60 1211.4TP53, CCNA2, CCNB1, BCL2, CDK1, CDKN2A
17adriamycin448.2FAS, TP53, CCNB1, BCL2, CDK1, CDKN2A
18ly294002448.2BCL2, CDK1, TNF, FAS, MAPK1, TP53
19olomoucine44 129.2TP53, CCNB1, CCNA2, MAPK1, BCL2, CDK1
20n acetylcysteine448.2MAPK1, FAS, TNF, TP53, BCL2, CDK1
21roscovitine448.2CCNA2, MAPK1, TP53, CDKN2A, CDK1, BCL2
22resveratrol44 60 25 1211.2CCNA2, FAS, BCL2, TP53, CCNB1, MAPK1
23mg 13244 609.2TNF, CDKN2A, TP53, FAS, CCNA2, CCNB1
24lactacystin448.1BCL2, TP53, CCNA2, CCNB1, MAPK1, CDK1
25camptothecin44 60 1210.0TP73, CCNA2, TP53, FAS, BCL2, CCNB1
26pd 98,059448.0TNF, CDKN2B, CDK1, BCL2, MAPK1, CCNB1
27paraffin448.0CDK1, BCL2, CCNB1, CCNA2, TP73, TP53
28progesterone44 29 60 25 1211.9TP53, CCNB1, CDKN2A, TP73, CDK1, CCNA2
29paclitaxel44 50 129.9FAS, CDKN2A, CDK1, BCL2, MAPK1, CCNB1
30rapamycin447.9CDK1, BCL2, FAS, IL7, CCNA2, CCNG2
31adpribose447.9CDK1, BCL2, CCNA2, FAS, TP53, TNF
32sp 60012544 608.9CDK1, BCL2, MAPK1, CCNB1, CCNA2, FAS
33thymidine44 258.8CDK1, TNF, TP53, FAS, CCNA2, MAPK1
34etoposide44 50 60 1210.8CCNA2, FAS, TP53, BCL2, CDK1, CCNB1
35sb 20358044 608.8TNF, TP53, FAS, CCNA2, CCNB1, MAPK1
36cycloheximide447.8MAPK1, TP53, FAS, TNF, IL7, CDKN2A
37doxorubicin44 50 129.8CCNA2, TP73, CCNB1, IL7, TP53, BCL2
38arsenite44 258.8MAPK1, TP53, FAS, CCNA2, CDKN2B, CCNB1
39genistein44 29 60 3 25 1212.7IL7, FAS, BCL2, TNF, CDKN2A, CDK1
40oxygen44 258.6TNF, CCNB1, CDK1, BCL2, IL7, CCNA2
41butyrate447.6CCNB1, MAPK1, BCL2, CDK1, CDKN2A, CCNA2
42oligonucleotide447.5SSBP3, IL7, CCNA2, CCNB1, BCL2, TP53
43h2o2447.5MAPK1, CDKN2A, CDK1, BCL2, CCNB1, CCNA2
44tyrosine447.4CDKN2B, CDK1, RHOH, MAPK1, IL7R, CCNB1
45threonine447.3SSBP3, CDK1, MAPK1, CCNB1, CCNA2, TP73
46vegf447.1IL7, CCNB1, BCL2, CDK1, TP73, TP53
47cisplatin44 50 60 129.9CDKN2A, CDK1, BCL2, CCNB1, CCNA2, MAPK1
48serine446.3CCNA2, CCNB1, IL7, CDK1, TNF, MAPK1
49estrogen446.2IL7, MAPK1, CDKN2B, CDKN2A, CDK1, CCNG2
50retinoic acid44 257.1TNF, CDKN2B, CDKN2A, CDK1, TP53, TP73

GO Terms for genes affiliated with Thyroid Lymphoma

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Cellular components related to Thyroid Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056548.1CCNA2, CCNB1, MAPK1, CDK1, CDKN2A, TP53
2cytosolGO:0058296.8TP53, TP73, FAS, CCNB1, MAPK1, BCL2
3cytoplasmGO:0057376.2CCNB1, CCNA2, FOXP1, FAS, TP53, CCNG2
4nucleusGO:0056345.1CDKN2B, PICALM, EBF3, TP53, TP73, FAS

Biological processes related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idNameGO IDScoreTop Affiliating Genes
1immunoglobulin productionGO:00237710.4FAS, IL7R
2regulation of G2/M transition of mitotic cell cycleGO:01038910.3CDKN2A, CCNA2
3renal system processGO:00301410.2BCL2, FAS
4negative regulation of phosphorylationGO:04232610.2RHOH, CDKN2A, CDKN2B
5T cell lineage commitmentGO:00236010.2IL7, TP53
6necroptotic signaling pathwayGO:09752710.2FAS, TNF
7transformed cell apoptotic processGO:00692710.2FAS, TNF
8spleen developmentGO:04853610.1FAS, BCL2, CDKN2B
9B cell lineage commitmentGO:00232610.1BCL2, TP53
10mitotic G1 DNA damage checkpointGO:03157110.1TP53, TP73
11replicative senescenceGO:09039910.0TP53, CDKN2A
12negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.0BCL2, IL7, TNF
13regulation of protein stabilityGO:0316479.9MAPK1, BCL2, CDKN2A
14release of cytochrome c from mitochondriaGO:0018369.9TP53, TP73, BCL2
15response to gamma radiationGO:0103329.9TP53, TP73, BCL2
16extrinsic apoptotic signaling pathway via death domain receptorsGO:0086259.9BCL2, FAS, TNF
17humoral immune responseGO:0069599.9TNF, IL7, BCL2
18intrinsic apoptotic signaling pathway in response to DNA damageGO:0086309.9TNF, TP73, BCL2
19regulation of cyclin-dependent protein serine/threonine kinase activityGO:0000799.9CDKN2B, CCNB1, CCNA2
20regulation of mitochondrial membrane permeabilityGO:0469029.9TP53, BCL2
21activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.9TNF, FAS, CDKN2A
22mitotic G2 DNA damage checkpointGO:0070959.9CCNA2, CDK1
23response to glucocorticoidGO:0513849.9BCL2, FAS, TNF
24cell cycle checkpointGO:0000759.9CDKN2A, CCNG2
25DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:0069789.8TP53, TP73
26organ morphogenesisGO:0098879.8MAPK1, IL7, TNF
27cell cycle arrestGO:0070509.8CDKN2B, CDKN2A, TP73, TP53
28response to salt stressGO:0096519.8TNF, TP53
29digestive tract morphogenesisGO:0485469.6BCL2, TP73
30cellular response to DNA damage stimulusGO:0069749.6TP53, TP73, MAPK1, BCL2
31cell agingGO:0075699.6CDK1, BCL2, TP53
32peptidyl-serine phosphorylationGO:0181059.5CDK1, BCL2, MAPK1
33ventricular cardiac muscle cell developmentGO:0550159.5CCNB1, CDK1
34cellular response to hypoxiaGO:0714569.5BCL2, CCNB1, TP53
35positive regulation of apoptotic processGO:0430659.5TNF, TP53, TP73, FAS
36MAPK cascadeGO:0001659.5TNF, MAPK1, CDK1
37negative regulation of cell growthGO:0303089.5CDKN2A, BCL2, TP53
38response to toxic substanceGO:0096369.4FAS, MAPK1, BCL2, CDK1
39activation of MAPK activityGO:0001879.3CDK1, MAPK1, TP73, TNF
40G2/M transition of mitotic cell cycleGO:0000869.3CCNA2, CCNB1, CDK1, CDKN2B
41negative regulation of cell proliferationGO:0082859.1TNF, TP53, CDKN2A, CDKN2B
42Ras protein signal transductionGO:0072659.0TP53, CCNA2, MAPK1, CDK1, CDKN2A
43mitotic cell cycleGO:0002789.0CDKN2B, CDKN2A, CDK1, CCNB1, CCNA2
44negative regulation of apoptotic processGO:0430669.0TP53, FAS, IL7, BCL2, CDK1
45response to drugGO:0424938.9TNF, CCNB1, BCL2, CDK1
46apoptotic processGO:0069158.6TNF, TP53, FAS, MAPK1, BCL2, CDK1
47positive regulation of transcription from RNA polymerase II promoterGO:0459448.6TNF, TP53, TP73, SSBP3, CDKN2A, CDKN2B
48positive regulation of transcription, DNA-templatedGO:0458938.3PICALM, EBF3, TNF, TP53, TP73, CCNA2
49transcription, DNA-templatedGO:0063518.1EBF3, TP73, SSBP3, FOXP1, MAPK1, CDKN2A
50protein complex assemblyGO:0064618.0CDK1, PICALM, TP53, FAS, SSBP3, CCNB1

Molecular functions related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.9CDKN2A, CDKN2B
2MDM2/MDM4 family protein bindingGO:0973719.9TP53, CDKN2A
3protein phosphatase 2A bindingGO:0517219.7BCL2, TP53
4p53 bindingGO:0020399.7CDKN2A, TP73, TP53
5protease bindingGO:0020209.4BCL2, TP53, TNF
6RNA polymerase II carboxy-terminal domain kinase activityGO:0083539.2CDK1, MAPK1
7transcription factor bindingGO:0081349.1TP53, TP73, MAPK1, BCL2, CDKN2A
8identical protein bindingGO:0428029.0TNF, TP53, TP73, FAS, BCL2
9protein kinase bindingGO:0199018.8TP53, TP73, CCNA2, CCNB1, CDKN2A, CDKN2B
10protein bindingGO:0055156.0CDKN2B, PICALM, TNF, TP53, TP73, FAS

Products for genes affiliated with Thyroid Lymphoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
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36MGI
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40NDF-RT
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44Novoseek
46OMIM
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51PubMed
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61UMLS
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