MCID: THY009
MIFTS: 54

Thyroid Lymphoma malady

Blood diseases, Cancer diseases, Rare diseases, Immune diseases categories
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Summaries for Thyroid Lymphoma

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65Wikipedia, 33MalaCards
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Wikipedia:65 Thyroid lymphoma is a rare malignant tumor constituting 1% to 2% of all thyroid malignancies and less... more...

MalaCards: Thyroid Lymphoma is related to colon cancer and thyroid cancer. An important gene associated with Thyroid Lymphoma is CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)), and among its related pathways are IL-7 Signaling and its Primary Biological Effects in Different Immune Cell Types and 14-3-3 and Regulation of BAD Activity. The compounds depsipeptide and noxa have been mentioned in the context of this disorder. Affiliated tissues include thyroid, b cells and colon, and related mouse phenotypes are pigmentation and vision/eye.

Aliases & Classifications for Thyroid Lymphoma

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8Disease Ontology, 10DISEASES, 49Orphanet, 62UMLS, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Blood diseases, Immune diseases


Aliases & Descriptions:

thyroid lymphoma 8 10 49 62


External Ids:

Disease Ontology8 DOID:10011
NCIt40 C5265

Related Diseases for Thyroid Lymphoma

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17GeneCards, 18GeneDecks
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Diseases related to Thyroid Lymphoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1colon cancer30.1TP53, TP73, FAS, CCNA2, IL7, MAPK1
2thyroid cancer29.9MAPK1, TP73, TP53, CCNB1
3b-cell lymphomas29.7BCL2, CDKN2B, CDKN2A, CCNB1, CCNA2, FOXP1
4leukemia29.4TNF, TP53, PICALM, CDKN2A, CDKN2B, TP73
5thyroiditis11.0
6subacute thyroiditis10.1
7goiter10.1
8hyperthyroidism10.1
9actinic keratosis10.1TP53
10meningioma10.1CDKN2B, TP73
11lymphopenia10.1FAS, IL7R, IL7
12anaplastic oligodendroglioma10.1CDKN2A, CDKN2B
13gamma chain deficiency10.1IL7R, IL7
14neuroblastoma10.1TP53
15cutaneous t cell lymphoma10.1CDKN2B, IL7R, IL7, FAS
16oropharyngeal cancer, adult10.0CDKN2A, TP53
17burkitt's lymphoma10.0TP73, BCL2, CDKN2B
18acute leukemia10.0CDKN2B, CCNA2, IL7, CCNB1
19lymphoma, diffuse large cell10.0CDKN2B, BCL2, PICALM
20bladder transitional cell carcinoma10.0CDKN2B, TP53
21cervical intraepithelial neoplasia10.0CDKN2A, CDK1, TP73
22acute lymphoblastic leukemia, childhood10.0CDKN2A, IL7, CDKN2B, CCNA2
23leukemia, acute lymphoblastic 310.0CDKN2B, TP73, CDKN2A, IL7
24li-fraumeni syndrome10.0CDKN2A, TP53
25nasopharynx carcinoma10.0CDKN2A, TP53
26human immunodeficiency virus infectious disease10.0IL7, IL7R
27kidney cancer10.0CCNB1, IL7, TP73, FAS
28colon adenocarcinoma10.0CCNA2, FAS, BCL2
29hematologic cancer10.0TP73, PICALM, CCNA2, IL7, CDKN2B
30medulloblastoma10.0TP53, CDKN2B, TP73
31bladder carcinoma10.0CDKN2A, CCNA2, TP53
32brain cancer10.0TP53, CDKN2B, CCNB1, TP73
33glioblastoma multiforme10.0CCNA2, TP53, CDKN2A, CDKN2B
34oligodendroglioma10.0CDKN2A, CDKN2B, TP73, TP53
35esophageal cancer10.0CDKN2A, TP73, CDKN2B, TP53
36papilloma10.0CDKN2A, CDKN2B, TP53, TP73
37graft versus host disease10.0TNF, FAS, IL7
38basal cell carcinoma10.0BCL2, CCNB1, TP53
39chronic lymphocytic leukemia10.0CDKN2B, CDK1, BCL2, IL7, CCNA2
40endometrial carcinoma10.0CDKN2A, CCNB1, TP53, TP73
41lung cancer10.0TP53, BCL2, CDKN2A
42breast cancer, invasive ductal10.0TP53, BCL2
43non-hodgkin lymphoma10.0CDKN2B, CDK1, IL7, FAS, BCL2
44chronic myeloid leukemia10.0CDKN2B, MAPK1, BCL2, CCNA2
45gastric adenocarcinoma10.0CDKN2B, FAS, MAPK1, BCL2
46oral cancer10.0TP73, CDKN2A, CDK1, CCNA2, TP53
47pancreatic cancer10.0FAS, MAPK1, CDKN2A
48lung benign neoplasm10.0CDKN2A, MAPK1, TP53
49multinodular goiter10.0
50cerebritis10.0

Graphical network of the top 20 diseases related to Thyroid Lymphoma:



Diseases related to thyroid lymphoma

Symptoms for Thyroid Lymphoma

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Drugs & Therapeutics for Thyroid Lymphoma

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Thyroid Lymphoma

Search NIH Clinical Center for Thyroid Lymphoma

Genetic Tests for Thyroid Lymphoma

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Anatomical Context for Thyroid Lymphoma

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33MalaCards
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MalaCards organs/tissues related to Thyroid Lymphoma:

33
Thyroid, B cells, Colon, T cells

Animal Models for Thyroid Lymphoma or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Thyroid Lymphoma:

37 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.1TP53, FAS, BCL2, CDKN2A
2MP:00053918.7TNF, TP53, TP73, FAS, BCL2, CDKN2A
3MP:00053818.5TNF, TP53, TP73, FAS, FOXP1, BCL2
4MP:00053698.4TNF, TP53, FOXP1, MAPK1, BCL2, CDKN2A
5MP:00107718.4TNF, TP53, FAS, MAPK1, BCL2, CDKN2A
6MP:00053888.2TNF, TP53, TP73, FAS, FOXP1, MAPK1
7MP:00053828.2TNF, TP53, TP73, FAS, SSBP3, BCL2
8MP:00053708.2PICALM, TNF, TP53, FAS, MAPK1, CDK1
9MP:00053908.1CDKN2A, SSBP3, FAS, TP73, TP53, TNF
10MP:00053798.0TNF, TP53, TP73, FAS, BCL2, CDK1
11MP:00053857.9TNF, TP53, TP73, FAS, FOXP1, MAPK1
12MP:00020067.7TNF, TP53, TP73, FAS, MAPK1, BCL2
13MP:00053897.7TNF, TP53, TP73, FAS, MAPK1, BCL2
14MP:00053767.1PICALM, TNF, TP53, TP73, FAS, FOXP1
15MP:00036317.1EBF3, TNF, TP53, TP73, FAS, SSBP3
16MP:00053787.1PICALM, TNF, TP53, TP73, FAS, SSBP3
17MP:00053977.0CDKN2B, PICALM, TNF, TP53, TP73, FAS
18MP:00053877.0FOXP1, FAS, TP73, TP53, TNF, PICALM
19MP:00053806.9PICALM, TNF, TP53, TP73, SSBP3, FOXP1
20MP:00053846.6FOXP1, FAS, TP73, TP53, TNF, PICALM
21MP:00107685.1FAS, TP73, TP53, TNF, EBF3, PICALM

Publications for Thyroid Lymphoma

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52PubMed
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Articles related to Thyroid Lymphoma:

(show top 50)    (show all 146)
idTitleAuthorsYear
1
A rare coexistence of thyroid lymphoma with papillary thyroid carcinoma. (24005594)
2013
2
Is 18F-FDG PET/CT useful for distinguishing between primary thyroid lymphoma and chronic thyroiditis? (23816945)
2013
3
Thyroid lymphoma incidentally detected by 18F-fluorocholine (FCH) PET/CT. (23856826)
2013
4
Importance of core biopsy in the diagnosis of thyroid lymphoma. (22507512)
2012
5
Primary mucosa-associated lymphoid tissue thyroid lymphoma: a rare thyroid neoplasm of extrathyroid origin. (22532918)
2012
6
Thyroid lymphoma: acute presentation and long-term outcome. (21835073)
2011
7
Fluorodeoxyglucose positron emission tomography in primary thyroid lymphoma with coexisting lymphocytic thyroiditis. (21875367)
2011
8
Untreated primary thyroid lymphoma in an elderly woman. (21727773)
2011
9
Primary thyroid lymphoma with elevated free thyroxine level. (21947158)
2011
10
Primary thyroid lymphoma (correction of lympoma): diagnostic and therapeutic dilemmas. (20620043)
2010
11
Thyroid Lymphoma as a Cause of Dysphagia and Dyspnea in a Patient without Palpable Nodules or Goiter. (19841755)
2009
12
Surgical treatment of primitive thyroid lymphoma. (20210235)
2009
13
Thyroid lymphoma: a rare tumor requiring combined management. (19671521)
2009
14
Thyroid lymphoma: beyond antigen stimulation. (19128828)
2009
15
Surgical trends in the management of thyroid lymphoma. (17604588)
2008
16
Thyroid lymphoma: early clinical suspicion may be critical for cure. (18852536)
2008
17
An evidence-based approach to the treatment of thyroid lymphoma. (17235456)
2007
18
FDG PET/CT for assessing therapy response in primary thyroid lymphoma. (17242576)
2007
19
HLA associations, microsatellite instability and epigenetic changes in thyroid lymphoma in Chinese. (17454594)
2007
20
High incidence of mucosa-associated lymphoid tissue in primary thyroid lymphoma: a clinicopathologic study of 18 cases in the Korean population. (17071486)
2006
21
Primary thyroid lymphoma mimicking subacute thyroiditis. (17152291)
2006
22
Anaplastic thyroid carcinoma, thyroid lymphoma, and metastasis to thyroid. (16882503)
2006
23
Anaplastic thyroid cancer and primary thyroid lymphoma: a review of these rare thyroid malignancies. (17131397)
2006
24
Fine needle aspiration cytology of primary thyroid lymphoma: a report of ten cases. (16336672)
2005
25
The incidence of primary thyroid lymphoma in thyroid malignancies. (16010091)
2004
26
Mucosa-associated lymphoid tissue thyroid lymphoma: a rare and not aggressive tumour. (12666700)
2002
27
Primary thyroid lymphoma is a heterogeneous disease. (11788631)
2002
28
Two unusual sites of colon cancer metastases and a rare thyroid lymphoma. Case 2. Chemotherapy-responsive right artial metastasis from colon carcinoma. (11481366)
2001
29
Frequent mutations of Fas gene in thyroid lymphoma. (11245438)
2001
30
A reassessment of primary thyroid lymphoma: high-grade MALT-type lymphoma as a distinct subtype of diffuse large B-cell lymphoma. (10931213)
2000
31
Down's syndrome with mucosa-associated lymphoid tissue, thyroid lymphoma and cerebral infarction. (10746421)
2000
32
Expression of interleukin-7 and its receptor in thyroid lymphoma. (11045564)
2000
33
Primary thyroid lymphoma. (10375088)
1999
34
Acute airway obstruction due to primary thyroid lymphoma. (9102733)
1996
35
Lethal tracheal dissolution during treatment for thyroid lymphoma. (7491567)
1995
36
Immunohistochemical detection of p53 and Bcl-2 proteins in Hashimoto's thyroiditis and primary thyroid lymphomas. (7730485)
1995
37
Immunologic type of thyroid lymphoma in an adult T-cell leukemia endemic area in Japan. (8580806)
1995
38
Thyroid lymphoma. The case for combined modality therapy. (8275426)
1994
39
Primary thyroid lymphoma: clinical features, treatment and outcome: a report of 8 cases. (8052462)
1994
40
The significance of MALT histology in thyroid lymphoma: a review of patients from the BNLI and Royal Marsden Hospital. (7826922)
1994
41
Monoclonal gammopathy as a clue to the presence of thyroid lymphoma associated with auto-immune thyroiditis. (1445050)
1992
42
MR imaging in patients with primary thyroid lymphoma. (1636536)
1992
43
Hashimoto's thyroiditis as a risk factor of thyroid lymphoma. (2220394)
1990
44
Hashimoto's disease, thyroid lymphoma and splenic atrophy. (2484910)
1989
45
Thyroid lymphoma. (2804581)
1989
46
MR imaging of primary thyroid lymphoma. (2723189)
1989
47
Laryngeal oedema complicating thyroid lymphoma. (3199019)
1988
48
Ultrasonography in the diagnosis of thyroid lymphoma. (3910657)
1985
49
Radiotherapeutic management of primary thyroid lymphoma. (3918965)
1985
50
Thyroid lymphoma in a patient with hyperthyroidism. (6702880)
1984

Variations for Thyroid Lymphoma

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Expression for genes affiliated with Thyroid Lymphoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Thyroid Lymphoma

Search GEO for disease gene expression data for Thyroid Lymphoma.

Pathways for genes affiliated with Thyroid Lymphoma

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Sources:
50PathCards, 54R&D Systems, 53QIAGEN, 38NCBI BioSystems Database, 55Reactome, 60Thomson Reuters, 30KEGG, 57SinoBiological, 5Cell Signaling Technology
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Pathways related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 100)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7IL7R, IL7, BCL2
29.5TP73, BCL2, TNF
3
Show member pathways
9.5FAS, BCL2, TNF
49.4BCL2, MAPK1, TNF
59.3CCNA2, TP53, CCNB1
6
Show member pathways
ATM Signaling Pathway38
9.3CCNB1, TP53, TP73
79.2TP53, MAPK1, CDKN2B, CDKN2A
8
Show member pathways
9.2CDKN2A, TP73, TP53, BCL2
9
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation60
9.2CDKN2B, CDK1, CCNA2, CDKN2A
10
Show member pathways
Apoptosis and survival Apoptotic TNF family pathways60
9.1BCL2, FAS, TNF, TP53
119.1CDKN2A, TP53, MAPK1, BCL2
12
Show member pathways
9.1CCNB1, CCNA2, CDK1
139.1CCNA2, CCNB1, CDK1
14
Show member pathways
IL-9 Signaling Pathway38
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway38
Immune response IL 9 signaling pathway60
9.1TNF, CCNA2, IL7, IL7R, MAPK1
15
Show member pathways
Alzheimers Disease38
9.1TNF, TP53, FAS, MAPK1
16
Show member pathways
9.1IL7, CDK1, MAPK1, IL7R
17
Show member pathways
9.0CDKN2A, TP53, CCNA2, MAPK1, CDKN2B
189.0TP53, IL7, MAPK1, IL7R, BCL2
19
Show member pathways
8.9CDK1, TP53, CCNB1
20
Show member pathways
Signaling Pathways in Glioblastoma38
8.9BCL2, CDKN2A, MAPK1, TP53, CDKN2B
21
Show member pathways
8.8TP53, CCNA2, CCNB1, CDKN2A, CDKN2B
228.8BCL2, MAPK1, FOXP1, CDKN2A, TP53
23
Show member pathways
Prostate Cancer38
Integrated Cancer pathway38
Steroid Biosynthesis38
8.8BCL2, CDK1, TP53, MAPK1
24
Show member pathways
Apoptosis and survival TNFR1 signaling pathway60
TWEAK Signaling Pathway38
Apoptosis Modulation by HSP7038
HIV-1 Nef- Negative effector of Fas and TNF-alpha38
8.8FAS, MAPK1, TNF, TP53, BCL2
25
Show member pathways
8.8FAS, TNF, TP53, MAPK1, BCL2
26
Show member pathways
8.8MAPK1, FAS, TP53, TNF, BCL2
27
Show member pathways
Cell cycle ESR1 regulation of G1 S transition60
Immune response MIF JAB1 signaling60
Cell cycle Cell cycle generic schema 60
8.8CCNB1, MAPK1, CDK1, CCNA2
28
Show member pathways
8.8CCNA2, CCNB1, MAPK1, CDK1
29
Show member pathways
PLK2 and PLK4 events38
Polo-like kinase signaling events in the cell cycle38
8.8CCNG2, CDKN2B, MAPK1, IL7R, CCNB1
308.7TP53, TP73, CCNB1, FAS, BCL2
318.7MAPK1, CDK1, TNF, TP53
328.7TP53, CDK1, CCNB1, CCNA2
338.7TP53, MAPK1, FAS, CDKN2B, CDKN2A, BCL2
34
Show member pathways
8.6BCL2, MAPK1, IL7R, IL7, TP53, TNF
35
Show member pathways
Apoptosis Modulation and Signaling38
Apoptosis38
8.6BCL2, TNF, TP53, TP73, FAS, CDKN2A
36
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
8.6MAPK1, BCL2, CCNA2, TP53, TNF, FAS
37
Show member pathways
DNA damage response (only ATM dependent)38
Wnt Signaling Pathway and Pluripotency38
8.4TP53, TP73, MAPK1, BCL2, CCNG2, CDKN2A
388.4CDK1, MAPK1, CCNA2, CDKN2B, TP53, CDKN2A
398.4CDKN2B, FAS, BCL2, MAPK1, CCNA2, TNF
40
Show member pathways
8.3TP53, FAS, IL7, BCL2, MAPK1, TNF
41
Show member pathways
Development EGFR signaling via PIP360
Development PDGF signaling via MAPK cascades60
Apoptosis and survival Anti apoptotic action of membrane bound ESR160
Signaling of Hepatocyte Growth Factor Receptor38
Development EGFR signaling via small GTPases60
Development Neurotrophin family signaling60
Apoptosis and survival NGF signaling pathway60
Apoptosis and survival Role of CDK5 in neuronal death and survival60
8.3TP53, FAS, CDK1, TP73, BCL2, MAPK1
42
Show member pathways
8.2TP53, CDK1, MAPK1, FAS, TNF, TP73
43
Show member pathways
Cell cycle38
8.2CDKN2A, CDK1, CDKN2B, CCNB1, CCNA2, TP53
44
Show member pathways
8.2CCNA2, CCNB1, MAPK1, BCL2, CDKN2A, CDKN2B
45
Show member pathways
8.2CCNB1, CDK1, CCNA2, TP73, TP53, CDKN2A
46
Show member pathways
8.1BCL2, IL7, TNF, TP53, IL7R, CDKN2B
47
Show member pathways
7.9TP53, CDKN2B, CDKN2A, CCNB1, MAPK1, CCNA2
48
Show member pathways
7.8CDKN2B, TP53, CCNA2, CCNB1, CCNG2, CDK1
49
Show member pathways
Proteasome Degradation38
Immune response Antigen presentation by MHC class I60
7.8TNF, TP53, CCNB1, BCL2, CDK1, FAS
50
Show member pathways
DNA damage response38
7.7CCNG2, CDK1, CDKN2A, FAS, TP53, CCNB1

Compounds for genes affiliated with Thyroid Lymphoma

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Sources:
45Novoseek, 11DrugBank, 51PharmGKB, 61Tocris Bioscience, 24HMDB, 29IUPHAR, 3BitterDB
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Compounds related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 151)
idCompoundScoreTop Affiliating Genes
1depsipeptide459.3FAS, CCNA2, BCL2, CDKN2A, TP53
2noxa459.2BCL2, FAS, TP73, TP53
3o6-methylguanine459.2CDKN2B, TP73, TP53, CDKN2A
4sulforaphane459.1MAPK1, FAS, BCL2, CCNA2, CCNB1
5c2ceramide458.9TP53, TNF, BCL2, MAPK1, FAS
6flavopiridol45 119.9CDKN2A, CDK1, BCL2, CCNA2, TP53
7vincristine45 51 1110.8BCL2, TP53, CDKN2A, CCNA2, CCNB1, TP73
8egcg458.8TNF, CDKN2A, BCL2, MAPK1, FAS, TP53
9thymidylate458.7FAS, CCNA2, TP53, CDK1, BCL2, CDKN2A
10cytarabine45 51 1110.6TP53, BCL2, FAS, CDKN2B, CDKN2A, CCNA2
11ceramide458.5CDK1, MAPK1, CCNA2, FAS, TNF, BCL2
12hydroxyurea45 51 1110.5TP53, CCNB1, CDKN2A, CCNA2, CDK1
13vinblastine45 51 1110.5CCNB1, CDK1, BCL2, CCNA2, TP53
145fluorouracil458.5BCL2, TP53, TP73, FAS, CCNA2, CDK1
15actinomycin d458.5BCL2, TP53, MAPK1, CDKN2A, FAS, TNF
16docetaxel45 51 61 1111.4TP53, CCNA2, CCNB1, BCL2, CDK1, CDKN2A
17adriamycin458.2FAS, TP53, CCNB1, BCL2, CDK1, CDKN2A
18ly294002458.2BCL2, CDK1, TNF, FAS, MAPK1, TP53
19olomoucine45 119.2TP53, CCNB1, CCNA2, MAPK1, BCL2, CDK1
20n acetylcysteine458.2MAPK1, FAS, TNF, TP53, BCL2, CDK1
21roscovitine458.2CCNA2, MAPK1, TP53, CDKN2A, CDK1, BCL2
22resveratrol45 61 24 1111.2CCNA2, FAS, BCL2, TP53, CCNB1, MAPK1
23mg 13245 619.2TNF, CDKN2A, TP53, FAS, CCNA2, CCNB1
24lactacystin458.1BCL2, TP53, CCNA2, CCNB1, MAPK1, CDK1
25camptothecin45 61 1110.0TP73, CCNA2, TP53, FAS, BCL2, CCNB1
26pd 98,059458.0TNF, CDKN2B, CDK1, BCL2, MAPK1, CCNB1
27paraffin458.0CDK1, BCL2, CCNB1, CCNA2, TP73, TP53
28progesterone45 29 61 24 1111.9TP53, CCNB1, CDKN2A, TP73, CDK1, CCNA2
29paclitaxel45 51 119.9FAS, CDKN2A, CDK1, BCL2, MAPK1, CCNB1
30rapamycin457.9CDK1, BCL2, FAS, IL7, CCNA2, CCNG2
31adpribose457.9CDK1, BCL2, CCNA2, FAS, TP53, TNF
32sp 60012545 618.9CDK1, BCL2, MAPK1, CCNB1, CCNA2, FAS
33thymidine45 248.8CDK1, TNF, TP53, FAS, CCNA2, MAPK1
34etoposide45 51 61 1110.8CCNA2, FAS, TP53, BCL2, CDK1, CCNB1
35sb 20358045 618.8TNF, TP53, FAS, CCNA2, CCNB1, MAPK1
36cycloheximide457.8MAPK1, TP53, FAS, TNF, IL7, CDKN2A
37doxorubicin45 51 119.8CCNA2, TP73, CCNB1, IL7, TP53, BCL2
38arsenite45 248.8MAPK1, TP53, FAS, CCNA2, CDKN2B, CCNB1
39genistein45 29 61 3 24 1112.7IL7, FAS, BCL2, TNF, CDKN2A, CDK1
40oxygen45 248.6TNF, CCNB1, CDK1, BCL2, IL7, CCNA2
41butyrate457.6CCNB1, MAPK1, BCL2, CDK1, CDKN2A, CCNA2
42oligonucleotide457.5SSBP3, IL7, CCNA2, CCNB1, BCL2, TP53
43h2o2457.5MAPK1, CDKN2A, CDK1, BCL2, CCNB1, CCNA2
44tyrosine457.4CDKN2B, CDK1, RHOH, MAPK1, IL7R, CCNB1
45threonine457.3SSBP3, CDK1, MAPK1, CCNB1, CCNA2, TP73
46vegf457.1IL7, CCNB1, BCL2, CDK1, TP73, TP53
47cisplatin45 51 61 119.9CDKN2A, CDK1, BCL2, CCNB1, CCNA2, MAPK1
48serine456.3CCNA2, CCNB1, IL7, CDK1, TNF, MAPK1
49estrogen456.2IL7, MAPK1, CDKN2B, CDKN2A, CDK1, CCNG2
50retinoic acid45 247.1TNF, CDKN2B, CDKN2A, CDK1, TP53, TP73

GO Terms for genes affiliated with Thyroid Lymphoma

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Sources:
16Gene Ontology
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Cellular components related to Thyroid Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056548.1CCNA2, CCNB1, MAPK1, CDK1, CDKN2A, TP53
2cytosolGO:0058296.8TP53, TP73, FAS, CCNB1, MAPK1, BCL2
3cytoplasmGO:0057376.2CCNB1, CCNA2, FOXP1, FAS, TP53, CCNG2
4nucleusGO:0056345.1CDKN2B, PICALM, EBF3, TP53, TP73, FAS

Biological processes related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idNameGO IDScoreTop Affiliating Genes
1immunoglobulin productionGO:00237710.4FAS, IL7R
2regulation of G2/M transition of mitotic cell cycleGO:01038910.3CDKN2A, CCNA2
3renal system processGO:00301410.2BCL2, FAS
4negative regulation of phosphorylationGO:04232610.2RHOH, CDKN2A, CDKN2B
5T cell lineage commitmentGO:00236010.2IL7, TP53
6necroptotic signaling pathwayGO:09752710.2FAS, TNF
7transformed cell apoptotic processGO:00692710.2FAS, TNF
8spleen developmentGO:04853610.1FAS, BCL2, CDKN2B
9B cell lineage commitmentGO:00232610.1BCL2, TP53
10mitotic G1 DNA damage checkpointGO:03157110.1TP53, TP73
11replicative senescenceGO:09039910.0TP53, CDKN2A
12negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.0BCL2, IL7, TNF
13regulation of protein stabilityGO:0316479.9MAPK1, BCL2, CDKN2A
14release of cytochrome c from mitochondriaGO:0018369.9TP53, TP73, BCL2
15response to gamma radiationGO:0103329.9TP53, TP73, BCL2
16extrinsic apoptotic signaling pathway via death domain receptorsGO:0086259.9BCL2, FAS, TNF
17humoral immune responseGO:0069599.9TNF, IL7, BCL2
18intrinsic apoptotic signaling pathway in response to DNA damageGO:0086309.9TNF, TP73, BCL2
19regulation of cyclin-dependent protein serine/threonine kinase activityGO:0000799.9CDKN2B, CCNB1, CCNA2
20regulation of mitochondrial membrane permeabilityGO:0469029.9TP53, BCL2
21activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.9TNF, FAS, CDKN2A
22mitotic G2 DNA damage checkpointGO:0070959.9CCNA2, CDK1
23response to glucocorticoidGO:0513849.9BCL2, FAS, TNF
24cell cycle checkpointGO:0000759.9CDKN2A, CCNG2
25DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:0069789.8TP53, TP73
26organ morphogenesisGO:0098879.8MAPK1, IL7, TNF
27cell cycle arrestGO:0070509.8CDKN2B, CDKN2A, TP73, TP53
28response to salt stressGO:0096519.8TNF, TP53
29digestive tract morphogenesisGO:0485469.6BCL2, TP73
30cellular response to DNA damage stimulusGO:0069749.6TP53, TP73, MAPK1, BCL2
31cell agingGO:0075699.6CDK1, BCL2, TP53
32peptidyl-serine phosphorylationGO:0181059.5CDK1, BCL2, MAPK1
33ventricular cardiac muscle cell developmentGO:0550159.5CCNB1, CDK1
34cellular response to hypoxiaGO:0714569.5BCL2, CCNB1, TP53
35positive regulation of apoptotic processGO:0430659.5TNF, TP53, TP73, FAS
36MAPK cascadeGO:0001659.5TNF, MAPK1, CDK1
37negative regulation of cell growthGO:0303089.5CDKN2A, BCL2, TP53
38response to toxic substanceGO:0096369.4FAS, MAPK1, BCL2, CDK1
39activation of MAPK activityGO:0001879.3CDK1, MAPK1, TP73, TNF
40G2/M transition of mitotic cell cycleGO:0000869.3CCNA2, CCNB1, CDK1, CDKN2B
41negative regulation of cell proliferationGO:0082859.1TNF, TP53, CDKN2A, CDKN2B
42Ras protein signal transductionGO:0072659.0TP53, CCNA2, MAPK1, CDK1, CDKN2A
43mitotic cell cycleGO:0002789.0CDKN2B, CDKN2A, CDK1, CCNB1, CCNA2
44negative regulation of apoptotic processGO:0430669.0TP53, FAS, IL7, BCL2, CDK1
45response to drugGO:0424938.9TNF, CCNB1, BCL2, CDK1
46apoptotic processGO:0069158.6TNF, TP53, FAS, MAPK1, BCL2, CDK1
47positive regulation of transcription from RNA polymerase II promoterGO:0459448.6TNF, TP53, TP73, SSBP3, CDKN2A, CDKN2B
48positive regulation of transcription, DNA-templatedGO:0458938.3PICALM, EBF3, TNF, TP53, TP73, CCNA2
49transcription, DNA-templatedGO:0063518.1EBF3, TP73, SSBP3, FOXP1, MAPK1, CDKN2A
50protein complex assemblyGO:0064618.0CDK1, PICALM, TP53, FAS, SSBP3, CCNB1

Molecular functions related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.9CDKN2A, CDKN2B
2MDM2/MDM4 family protein bindingGO:0973719.9TP53, CDKN2A
3protein phosphatase 2A bindingGO:0517219.7BCL2, TP53
4p53 bindingGO:0020399.7CDKN2A, TP73, TP53
5protease bindingGO:0020209.4BCL2, TP53, TNF
6RNA polymerase II carboxy-terminal domain kinase activityGO:0083539.2CDK1, MAPK1
7transcription factor bindingGO:0081349.1TP53, TP73, MAPK1, BCL2, CDKN2A
8identical protein bindingGO:0428029.0TNF, TP53, TP73, FAS, BCL2
9protein kinase bindingGO:0199018.8TP53, TP73, CCNA2, CCNB1, CDKN2A, CDKN2B
10protein bindingGO:0055156.0CDKN2B, PICALM, TNF, TP53, TP73, FAS

Products for genes affiliated with Thyroid Lymphoma

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Sources for Thyroid Lymphoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet