MCID: THY009
MIFTS: 47

Thyroid Lymphoma malady

Categories: Blood diseases, Rare diseases, Cancer diseases, Immune diseases, Endocrine diseases

Aliases & Classifications for Thyroid Lymphoma

Summaries for Thyroid Lymphoma

MalaCards based summary : Thyroid Lymphoma is related to lymphoma and thyroiditis, and has symptoms including pain, respiratory distress and stridor. An important gene associated with Thyroid Lymphoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Cell Cycle, Mitotic and Cellular Senescence. The drugs rituximab and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include thyroid, b cells and colon, and related phenotypes are hematopoietic system and immune system

Wikipedia : 71 Thyroid lymphoma is a rare malignant tumor constituting 1% to 2% of all thyroid malignancies and less... more...

Related Diseases for Thyroid Lymphoma

Diseases related to Thyroid Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
id Related Disease Score Top Affiliating Genes
1 lymphoma 10.6
2 thyroiditis 10.6
3 clear cell adenofibroma 10.2 CDKN2A TP53
4 lacrimal gland adenoid cystic carcinoma 10.2 CDKN2A TP53
5 pericardium leiomyoma 10.2 CDKN2A TP53
6 spondylarthropathy 10.2 CDKN2A TP53
7 lacrimal gland squamous cell carcinoma 10.2 CDKN2A TP53
8 endometrial squamous cell carcinoma 10.2 CDKN2A TP53
9 coccidiosis 10.2 CDKN2A TP53
10 postpoliomyelitis syndrome 10.2 CDKN2A TP53
11 paraphimosis 10.2 CDKN2A TP53
12 anal carcinoma in situ 10.2 CDKN2A TP53
13 oro-mandibular-limb hypogenesis syndrome 10.2 CDKN2A TP53
14 brain stem medulloblastoma 10.2 CDKN2A TP53
15 fragile x-associated tremor/ataxia syndrome 10.2 CDKN2A TP53
16 spastic ataxia 5 10.2 CDKN2A TP53
17 gallbladder pleomorphic giant cell adenocarcinoma 10.2 CDKN2A TP53
18 adult epithelioid sarcoma 10.2 CDKN2A TP53
19 cervical verrucous carcinoma 10.2 CDKN2A TP53
20 uterine cervix leukoplakia 10.2 CDKN2A TP53
21 house allergic alveolitis 10.2 CDKN2A TP53
22 acquired hemangioma 10.2 CDKN2A TP53
23 urethral verrucous carcinoma 10.2 CDKN2A TP53
24 chronic monocytic leukemia 10.2 CDKN2A TP53
25 ossifying fibromyxoid tumor 10.2 CDKN2A TP53
26 thymus squamous cell carcinoma 10.2 CDKN2A TP53
27 aicardi-goutieres syndrome 10.2 CDKN2A TP53
28 glomangioma 10.2 CDKN2B TP53
29 congenital sucrase-isomaltase deficiency without sucrose intolerance 10.2 CCNA2 TP53
30 secondary hyperparathyroidism of renal origin 10.2 CDKN2A TP53
31 spinal cord oligodendroglioma 10.1 CDKN2A TP53
32 monckeberg arteriosclerosis 10.1 CDKN2A CDKN2B
33 plasmodium ovale malaria 10.1 CDKN2A TP53
34 pacinian tumor 10.1 CDKN2A TP53
35 vascular myelopathy 10.1 CDKN2A TP53
36 tamoxifen-related endometrial lesion 10.1 CDKN2A TP53
37 placental site trophoblastic tumor 10.1 CDKN2A TP53
38 extranodal nasal nk/t cell lymphoma 10.1 CDKN2A CDKN2B
39 myxedema 10.1 CDKN2A TP53
40 paroxysmal nocturnal hemoglobinuria 10.1 CDKN2A IL7 TP53
41 granulomatous myositis 10.1 CDKN2A TP53
42 thanatophoric dysplasia, type ii 10.1 CCNB1 CDKN2A TP53
43 adrenal cortical carcinoma 10.1 CCNB1 CDKN2A TP53
44 hypotrichosis 8 10.1 CCNB1 CDKN2A TP53
45 cryoglobulinemia 10.0 CDKN2A TP53
46 estrogen-receptor positive breast cancer 10.0 CDKN2A TP53
47 uterine disease 10.0 CDKN2A CDKN2B TP53
48 interstitial lung disease 10.0 CDKN2A CDKN2B TP53
49 lattice corneal dystrophy 10.0 CDKN2A CDKN2B TP53
50 thoracic outlet syndrome 10.0 CDKN2A CDKN2B TP53

Graphical network of the top 20 diseases related to Thyroid Lymphoma:



Diseases related to Thyroid Lymphoma

Symptoms & Phenotypes for Thyroid Lymphoma

Human phenotypes related to Thyroid Lymphoma:

56 32 (show all 14)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 pain 56 32 Occasional (29-5%) HP:0012531
2 respiratory distress 56 32 Very rare (<4-1%) HP:0002098
3 stridor 56 32 Frequent (79-30%) HP:0010307
4 hypothyroidism 56 32 Frequent (79-30%) HP:0000821
5 dysphagia 56 32 Frequent (79-30%) HP:0002015
6 hashimoto thyroiditis 56 32 Frequent (79-30%) HP:0000872
7 hyperthyroidism 56 32 Occasional (29-5%) HP:0000836
8 goiter 56 32 Obligate (100%) HP:0000853
9 lymphoma 56 32 Obligate (100%) HP:0002665
10 hoarse voice 56 32 Frequent (79-30%) HP:0001609
11 lymphadenopathy 56 32 Frequent (79-30%) HP:0002716
12 upper airway obstruction 56 32 Frequent (79-30%) HP:0002781
13 broad neck 56 32 Very frequent (99-80%) HP:0000475
14 dyspnea 56 Frequent (79-30%)

MGI Mouse Phenotypes related to Thyroid Lymphoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CCNA2 CDKN2A CDKN2B IL7 IL7R PICALM
2 immune system MP:0005387 9.17 CDKN2B IL7 IL7R PICALM TP53 CCNA2

Drugs & Therapeutics for Thyroid Lymphoma

Drugs for Thyroid Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 126)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
rituximab Approved Phase 4,Phase 3,Phase 2 174722-31-7 10201696
2
Methotrexate Approved Phase 4 1959-05-2, 59-05-2 126941
3
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
4
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
5
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
6
leucovorin Approved, Nutraceutical Phase 4 58-05-9 54575, 6560146 143
7 Antibodies Phase 4,Phase 3,Phase 2
8 Antiemetics Phase 4,Phase 2
9 Antimetabolites Phase 4,Phase 2,Phase 3,Phase 1
10 Antimetabolites, Antineoplastic Phase 4,Phase 2,Phase 1
11 Antirheumatic Agents Phase 4,Phase 3,Phase 2
12 Autonomic Agents Phase 4,Phase 2
13 Dermatologic Agents Phase 4,Phase 2
14 Gastrointestinal Agents Phase 4,Phase 2
15 Immunoglobulins Phase 4,Phase 3,Phase 2
16 Immunosuppressive Agents Phase 4,Phase 2,Phase 1
17 Peripheral Nervous System Agents Phase 4,Phase 2
18 Protective Agents Phase 4,Early Phase 1
19 Anti-Inflammatory Agents Phase 4
20 Antineoplastic Agents, Hormonal Phase 4
21 Folic Acid Antagonists Phase 4
22 glucocorticoids Phase 4
23 Hormone Antagonists Phase 4
24 Hormones Phase 4
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
26 Methylprednisolone acetate Phase 4
27 Methylprednisolone Hemisuccinate Phase 4
28 Neuroprotective Agents Phase 4
29 Nucleic Acid Synthesis Inhibitors Phase 4
30 Prednisolone acetate Phase 4
31 Prednisolone hemisuccinate Phase 4
32 Prednisolone phosphate Phase 4
33 Vitamin B Complex Phase 4
34 Folate Nutraceutical Phase 4
35 Vitamin B9 Nutraceutical Phase 4
36 Anti-Infective Agents Phase 3,Phase 2,Phase 1
37 Antiviral Agents Phase 2, Phase 3
38 Antibodies, Monoclonal Phase 3,Phase 2
39 Anti-Infective Agents, Local Phase 3,Phase 2
40 cadexomer iodine Phase 3,Phase 2,Early Phase 1
41
Iodine Phase 3,Phase 2,Early Phase 1 7553-56-2 807
42 Iodine-131 anti-B1 antibody Phase 3,Phase 2
43 Micronutrients Phase 3,Phase 2
44 Trace Elements Phase 3,Phase 2
45 Deoxyglucose Phase 2, Phase 3
46 Fluorodeoxyglucose F18 Phase 2, Phase 3
47 Radiopharmaceuticals Phase 2, Phase 3
48
Indinavir Approved Phase 2 150378-17-9 5362440
49
Ritonavir Approved, Investigational Phase 2 155213-67-5 392622
50
Bortezomib Approved, Investigational Phase 1, Phase 2 179324-69-7 387447 93860

Interventional clinical trials:

(show all 40)
id Name Status NCT ID Phase
1 Rituximab (RTX) Therapy in Patients With Active TAO Recruiting NCT02378298 Phase 4
2 Comparison Of Rituximab Versus Tositumomab and Iodine I 131 Tositumomab (BEXXAR® Therapeutic Regimen) For Patients With Relapsed Follicular Non-Hodgkins Lymphoma Completed NCT00268983 Phase 3
3 Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Cancer or Suspected Cancer Completed NCT00123760 Phase 2, Phase 3
4 Radiation Dose Optimization in Diffuse Large B- Cell Lymphoma. Recruiting NCT02964858 Phase 3
5 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2
6 Retreatment of Patients With Non-Hodgkin's Lymphoma Who Have Previously Responded to Iodine-131 Anti B1 Antibody Completed NCT00938041 Phase 2
7 Expanded Access Study Of BEXXAR® For Low Grade And Transformed Low-Grade Non-Hodgkin's Lymphoma Completed NCT00268203 Phase 2
8 A Randomized Study of Iodine-131 Anti-b1 Antibody Versus Anti-b1 Antibody in Chemotherapy-relapsed/Refractory Low-grade or Transformed Low-grade Non-Hodgkin's Lymphoma (NHL) Completed NCT01573000 Phase 2
9 Iodine-131 Anti-B1 Antibody Consolidation for Patients With Non-Hodgkin's Lymphoma Following First-line CHOP Completed NCT01868035 Phase 2
10 A Targeted Phase I/II Trial of ZD6474 (Vandetanib; ZACTIMA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults With Solid Tumors With a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Cancer (MTC) Completed NCT00923247 Phase 1, Phase 2
11 Study of Iodine-131 Anti-B1 Antibody for Patients With Non Hodgkin's Lymphoma Who Have Previously Received Rituximab Completed NCT00996593 Phase 2
12 Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody Plus CHOP For Untreated Mantle Cell Lymphoma Completed NCT00992992 Phase 2
13 A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H... Completed NCT00923481 Phase 2
14 Phase 2 Study of Bexxar in Relapsed/Refractory DLCL Completed NCT00490009 Phase 2
15 Iodine-131 Anti-B1 Antibody (Tositumomab and Iodine I 131 Tositumomab) for Previously Untreated, Advanced-stage, Low Grade Non-Hodgkin's Lymphoma Completed NCT00996996 Phase 2
16 Study of Safety and Efficacy of a Sequential Regimen Consisting of Three Cycles of Fludarabine Followed by Tositumomab and Iodine I 131 Tositumomab Completed NCT00933335 Phase 2
17 Study of Iodine 131 Anti B1 Antibody for 1st or 2nd Relapsed Indolent B-Cell Lymphomas or B-Cell Lymphomas That Have Transformed to a More Aggressive Histology Completed NCT00950755 Phase 2
18 Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium Completed NCT00896454 Phase 2
19 Zoledronic Acid in Preventing Osteoporosis in Patients Undergoing Donor Stem Cell Transplant Completed NCT00321932 Phase 2
20 Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions) Recruiting NCT02568267 Phase 2
21 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
22 Study of XL184 (Cabozantinib) in Adults With Advanced Malignancies Completed NCT00215605 Phase 1
23 Depsipeptide to Treat Thyroid and Other Advanced Cancers Completed NCT00048334 Phase 1
24 Study of Oral PXD101 in Patients With Advanced Solid Tumors or Lymphoma Completed NCT00413075 Phase 1
25 Spectroscopy With Surface Coils and Decoupling Completed NCT00581815 Phase 1
26 Rapamycin With Grapefruit Juice for Advanced Malignancies Completed NCT00375245 Phase 1
27 Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction Recruiting NCT01638533 Phase 1
28 Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies Recruiting NCT02223052 Phase 1
29 11C-Acetate PET/CT Non-FDG-Avid Tumors Unknown status NCT00687778
30 Association Between Hepatitis C Virus Infection and Hematologic and Thyroid Cancers Completed NCT00342641
31 A Pilot Clinical Trial for Poorly Differentiated Thyroid Cancer - Correlation to Retinoid and Peroxisome-proliferator-activated Receptor (PPARy) Expression Completed NCT00718770 Early Phase 1
32 B-Receptor Signaling in Cardiomyopathy Completed NCT01135849
33 Vegetable Garden Feasibility Trial to Promote Function in Older Cancer Survivors Completed NCT02150148
34 The Effect of Human Placental Explants and Pregnant Women Sera on Cancer Cells Recruiting NCT01879436
35 PET Imaging of Patients Using 124I-PU-AD Recruiting NCT02751554
36 10 Year Registry of Children (Ages 2-17 Years) With Eczema That Have Used Pimecrolimus Recruiting NCT00568997
37 Evaluation of Adverse Long-term Effects in Young Adult Survivors of Acute Leukemia Recruiting NCT02345915 Early Phase 1
38 Non-Invasive Cerenkov Luminescence Imaging of Lymphoma, Leukemia and Metastatic Lymph Nodes Active, not recruiting NCT01664936
39 Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy Active, not recruiting NCT02062632
40 Cardiometabolic Status in Childhood Acute Lymphoblastic Leukemia Withdrawn NCT01688752

Search NIH Clinical Center for Thyroid Lymphoma

Genetic Tests for Thyroid Lymphoma

Anatomical Context for Thyroid Lymphoma

MalaCards organs/tissues related to Thyroid Lymphoma:

39
Thyroid, B Cells, Colon, T Cells

Publications for Thyroid Lymphoma

Articles related to Thyroid Lymphoma:

(show top 50) (show all 182)
id Title Authors Year
1
Primary thyroid lymphoma: A case report and review of the literature. ( 28053701 )
2017
2
Pathology Verified Concomitant Papillary Thyroid Carcinoma in the Sonographically Suspected Thyroid Lymphoma: A Case Report. ( 28031089 )
2016
3
Residual FDG uptake of primary thyroid lymphoma after treatment may overestimate residual lymphoma. ( 27614754 )
2016
4
Primary thyroid lymphoma presenting as dermatomyositis: a first case and review of the literature. ( 27126096 )
2016
5
Wnt5a and Ror2 expression associate with the disease progress of primary thyroid lymphoma. ( 26614433 )
2016
6
Development of Primary Thyroid Lymphoma during an Ultrasonographic Follow-up of Hashimoto's Thyroiditis: A Report of 9 Cases. ( 27086809 )
2016
7
Efficacy of Fine-Needle Aspiration Cytology in the Diagnosis of Primary Thyroid Lymphoma for Elderly Adults. ( 27557116 )
2016
8
Primary thyroid lymphoma. ( 26985163 )
2016
9
Wnt5a and Ror2 expression associate with the disease progress of primary thyroid lymphoma. ( 26608372 )
2016
10
Clinical Presentation and Diagnostic Challenges of Thyroid Lymphoma: A Cohort Study. ( 27256107 )
2016
11
Complete resolution of autoimmune thyroiditis after R-CHOP in a patient with thyroid lymphoma. ( 26687264 )
2015
12
Evaluation of primary thyroid lymphoma by ultrasonography combined with contrast-enhanced ultrasonography: A pilot study. ( 26960472 )
2015
13
Core needle biopsy could reduce diagnostic surgery in patients with anaplastic thyroid cancer or thyroid lymphoma. ( 26201291 )
2015
14
12 cases of primary thyroid lymphoma in China. ( 25736543 )
2015
15
Primary thyroid lymphoma: multi-slice computed tomography findings. ( 25735344 )
2015
16
Hoarseness: an unusual presentation of primary thyroid lymphoma with laryngeal infiltration. ( 26411267 )
2015
17
Primary thyroid lymphoma: The two ends of the spectrum. ( 26416071 )
2015
18
Primary thyroid lymphoma has different sonographic and color Doppler features compared to nodular goiter. ( 25614405 )
2015
19
Clinicopathological characteristics and treatment outcomes of 38 cases of primary thyroid lymphoma: a multicenter study. ( 26665123 )
2015
20
Primary thyroid lymphoma: case series with review of literature. ( 25332615 )
2014
21
Thyroid lymphoma on a background of Hashimoto's thyroiditis: PET/CT appearances. ( 24679651 )
2014
22
Primary thyroid lymphoma. ( 24935697 )
2014
23
Rituximab-including combined modality treatment for primary thyroid lymphoma: an effective regimen for elderly patients. ( 24547778 )
2014
24
Sonographic appearance of primary thyroid lymphoma-preliminary experience. ( 25474402 )
2014
25
Aggressive primary thyroid lymphoma: imaging features of two elderly patients. ( 25060184 )
2014
26
Non-Hodgkin's thyroid lymphoma associated with Hashimoto's thyroiditis. ( 24864614 )
2014
27
Hypothyroidism after radiotherapy for primary thyroid lymphoma. ( 25075081 )
2014
28
Identification of primary thyroid lymphoma with medical imaging: A case report and review of the literature. ( 25364417 )
2014
29
Fine needle cytology and flow cytometry in hashimoto thyroiditis and primary thyroid lymphoma. ( 24642841 )
2014
30
Primary thyroid lymphoma: A rare disease. ( 25745292 )
2014
31
Diagnosing thyroid lymphoma: steroid administration may result in rapid improvement of dyspnea : a report of two cases. ( 24696693 )
2014
32
Thyroid lymphoma incidentally detected by 18F-fluorocholine (FCH) PET/CT. ( 23856826 )
2013
33
Thyroid lymphoma: recent advances in diagnosis and optimal management strategies. ( 23881987 )
2013
34
Tracheal invasion and perforation from advanced primary thyroid lymphoma: a case report and literature review. ( 23702317 )
2013
35
Thyroid lymphoma: diagnostic pitfalls on pre-operative ago-biopsy. ( 23134840 )
2013
36
Patterns of care and treatment outcomes for primary thyroid lymphoma: a single institution study. ( 24501704 )
2013
37
A rare coexistence of thyroid lymphoma with papillary thyroid carcinoma. ( 24005594 )
2013
38
Clinicopathologic study and outcome analysis of thyroid lymphomas: experience from a tertiary cancer center. ( 22368156 )
2013
39
Primary thyroid lymphoma: a series of two cases and review of literature. ( 24772759 )
2013
40
Is 18F-FDG PET/CT useful for distinguishing between primary thyroid lymphoma and chronic thyroiditis? ( 23816945 )
2013
41
Primary thyroid lymphoma: a clinical review. ( 23714679 )
2013
42
Ulcerative colitis associated with extranodal marginal zone B-cell thyroid lymphoma of mucosa-associated lymphoid tissue and Hashimoto thyroiditis: description of a case. ( 24714310 )
2013
43
Primary thyroid lymphoma: the 40 year experience of a UK lymphoma treatment centre. ( 22367111 )
2012
44
Thyroid carcinoma-associated genetic mutations also occur in thyroid lymphomas. ( 22575864 )
2012
45
Thyroid lymphoma: correlation of radiologic and pathologic features. ( 22441916 )
2012
46
Primary thyroid lymphoma arising from Hashimotos thyroiditis diagnosed by fine needle aspiration cytology. ( 22531543 )
2012
47
Cytodiagnosis of primary thyroid lymphoma with histologic correlation: A case report. ( 21681970 )
2012
48
Thyroid lymphoma. ( 23094430 )
2012
49
Importance of core biopsy in the diagnosis of thyroid lymphoma. ( 22507512 )
2012
50
Primary mucosa-associated lymphoid tissue thyroid lymphoma: a rare thyroid neoplasm of extrathyroid origin. ( 22532918 )
2012

Variations for Thyroid Lymphoma

Expression for Thyroid Lymphoma

Search GEO for disease gene expression data for Thyroid Lymphoma.

Pathways for Thyroid Lymphoma

Pathways related to Thyroid Lymphoma according to GeneCards Suite gene sharing:

(show all 32)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.15 CCNA2 CCNB1 CDKN2A CDKN2B TP53
2
Show member pathways
12.9 CCNA2 CDKN2A CDKN2B TP53
3
Show member pathways
12.71 CCNA2 CCNB1 CDKN2A TP53
4
Show member pathways
12.22 CCNA2 CCNB1 TP53
5 12.2 CDKN2A CDKN2B TP53
6 12.2 CCNA2 CCNB1 CDKN2A TP53
7
Show member pathways
12.14 CCNB1 CDKN2A TP53
8
Show member pathways
12.07 CCNA2 CCNB1 CDKN2A CDKN2B TP53
9
Show member pathways
11.97 CCNA2 CDKN2A CDKN2B
10 11.97 CCNA2 CDKN2A CDKN2B TP53
11
Show member pathways
11.84 CCNB1 CDKN2B IL7R
12 11.82 CCNB1 CDKN2A TP53
13 11.71 CCNA2 CCNB1 CDKN2A CDKN2B TP53
14
Show member pathways
11.68 CCNA2 CCNB1 TP53
15 11.6 CCNA2 CCNB1 TP53
16
Show member pathways
11.5 CCNA2 CDKN2A TP53
17 11.39 CCNA2 CCNB1
18 11.38 CDKN2A TP53
19
Show member pathways
11.37 CCNA2 CCNB1 CDKN2A CDKN2B TP53
20 11.3 CDKN2B TP53
21
Show member pathways
11.29 CCNB1 TP53
22 11.29 CCNA2 CDKN2A TP53
23 11.28 CCNA2 TP53
24
Show member pathways
11.27 IL7 IL7R
25
Show member pathways
11.16 CCNA2 CCNB1
26 11.12 CCNA2 CCNB1
27 11.02 IL7 IL7R
28 11 CCNA2 CCNB1 TP53
29 10.94 CDKN2A CDKN2B TP53
30 10.91 CDKN2A TP53
31
Show member pathways
10.9 CDKN2A TP53
32 10.82 CCNB1 TP53

GO Terms for Thyroid Lymphoma

Biological processes related to Thyroid Lymphoma according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.78 CCNA2 CDKN2A PICALM TP53
2 cell cycle arrest GO:0007050 9.61 CDKN2A CDKN2B TP53
3 G2/M transition of mitotic cell cycle GO:0000086 9.58 CCNA2 CCNB1 CDKN2B
4 positive regulation of fibroblast proliferation GO:0048146 9.51 CCNA2 CCNB1
5 protein complex assembly GO:0006461 9.5 CCNB1 PICALM TP53
6 regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079 9.49 CCNA2 CDKN2B
7 negative regulation of phosphorylation GO:0042326 9.46 CDKN2A CDKN2B
8 regulation of G2/M transition of mitotic cell cycle GO:0010389 9.37 CCNA2 CDKN2A
9 cellular response to hypoxia GO:0071456 9.33 CCNA2 CCNB1 TP53
10 replicative senescence GO:0090399 9.26 CDKN2A TP53
11 Ras protein signal transduction GO:0007265 9.13 CCNA2 CDKN2A TP53
12 cell cycle GO:0007049 9.02 CCNA2 CCNB1 CDKN2A CDKN2B TP53

Molecular functions related to Thyroid Lymphoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein kinase binding GO:0019901 9.02 CCNA2 CCNB1 CDKN2A CDKN2B TP53
2 cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861 8.96 CDKN2A CDKN2B

Sources for Thyroid Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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