MCID: THY009
MIFTS: 54

Thyroid Lymphoma malady

Blood diseases, Cancer diseases, Rare diseases, Immune diseases categories

Summaries for Thyroid Lymphoma

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66Wikipedia, 34MalaCards
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Wikipedia:66 Thyroid lymphoma is a rare malignant tumor constituting 1% to 2% of all thyroid malignancies and less... more...

MalaCards: Thyroid Lymphoma is related to colon cancer and thyroid cancer. An important gene associated with Thyroid Lymphoma is CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)), and among its related pathways are IL-7 Signaling and its Primary Biological Effects in Different Immune Cell Types and 14-3-3 and Regulation of BAD Activity. The compounds depsipeptide and noxa have been mentioned in the context of this disorder. Affiliated tissues include thyroid, b cells and colon, and related mouse phenotypes are pigmentation and vision/eye.

Aliases & Classifications for Thyroid Lymphoma

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9Disease Ontology, 11DISEASES, 50Orphanet, 63UMLS, 41NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Blood diseases, Immune diseases


Aliases & Descriptions:

thyroid lymphoma 9 11 50 63


External Ids:

Disease Ontology9 DOID:10011
NCIt41 C5265

Related Diseases for Thyroid Lymphoma

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18GeneCards, 19GeneDecks
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Diseases related to Thyroid Lymphoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1colon cancer30.1TP53, TP73, FAS, CCNA2, IL7, MAPK1
2thyroid cancer29.9MAPK1, TP73, TP53, CCNB1
3b-cell lymphomas29.7BCL2, CDKN2B, CDKN2A, CCNB1, CCNA2, FOXP1
4leukemia29.4TNF, TP53, PICALM, CDKN2A, CDKN2B, TP73
5thyroiditis11.0
6subacute thyroiditis10.1
7goiter10.1
8hyperthyroidism10.1
9actinic keratosis10.1TP53
10meningioma10.1CDKN2B, TP73
11lymphopenia10.1FAS, IL7R, IL7
12anaplastic oligodendroglioma10.1CDKN2A, CDKN2B
13gamma chain deficiency10.1IL7R, IL7
14neuroblastoma10.1TP53
15cutaneous t cell lymphoma10.1CDKN2B, IL7R, IL7, FAS
16oropharyngeal cancer, adult10.0CDKN2A, TP53
17burkitt's lymphoma10.0TP73, BCL2, CDKN2B
18acute leukemia10.0CDKN2B, CCNA2, IL7, CCNB1
19lymphoma, diffuse large cell10.0CDKN2B, BCL2, PICALM
20bladder transitional cell carcinoma10.0CDKN2B, TP53
21cervical intraepithelial neoplasia10.0CDKN2A, CDK1, TP73
22acute lymphoblastic leukemia, childhood10.0CDKN2A, IL7, CDKN2B, CCNA2
23leukemia, acute lymphoblastic 310.0CDKN2B, TP73, CDKN2A, IL7
24li-fraumeni syndrome10.0CDKN2A, TP53
25nasopharynx carcinoma10.0CDKN2A, TP53
26human immunodeficiency virus infectious disease10.0IL7, IL7R
27kidney cancer10.0CCNB1, IL7, TP73, FAS
28colon adenocarcinoma10.0CCNA2, FAS, BCL2
29hematologic cancer10.0TP73, PICALM, CCNA2, IL7, CDKN2B
30medulloblastoma10.0TP53, CDKN2B, TP73
31bladder carcinoma10.0CDKN2A, CCNA2, TP53
32brain cancer10.0TP53, CDKN2B, CCNB1, TP73
33glioblastoma multiforme10.0CCNA2, TP53, CDKN2A, CDKN2B
34oligodendroglioma10.0CDKN2A, CDKN2B, TP73, TP53
35esophageal cancer10.0CDKN2A, TP73, CDKN2B, TP53
36papilloma10.0CDKN2A, CDKN2B, TP53, TP73
37graft versus host disease10.0TNF, FAS, IL7
38basal cell carcinoma10.0BCL2, CCNB1, TP53
39chronic lymphocytic leukemia10.0CDKN2B, CDK1, BCL2, IL7, CCNA2
40endometrial carcinoma10.0CDKN2A, CCNB1, TP53, TP73
41lung cancer10.0TP53, BCL2, CDKN2A
42breast cancer, invasive ductal10.0TP53, BCL2
43non-hodgkin lymphoma10.0CDKN2B, CDK1, IL7, FAS, BCL2
44chronic myeloid leukemia10.0CDKN2B, MAPK1, BCL2, CCNA2
45gastric adenocarcinoma10.0CDKN2B, FAS, MAPK1, BCL2
46oral cancer10.0TP73, CDKN2A, CDK1, CCNA2, TP53
47pancreatic cancer10.0FAS, MAPK1, CDKN2A
48lung benign neoplasm10.0CDKN2A, MAPK1, TP53
49multinodular goiter10.0
50cerebritis10.0

Graphical network of the top 20 diseases related to Thyroid Lymphoma:



Diseases related to thyroid lymphoma

Symptoms for Thyroid Lymphoma

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Drugs & Therapeutics for Thyroid Lymphoma

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Thyroid Lymphoma

Drug clinical trials:

Search ClinicalTrials for Thyroid Lymphoma

Search NIH Clinical Center for Thyroid Lymphoma

Search CenterWatch for Thyroid Lymphoma

Genetic Tests for Thyroid Lymphoma

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Anatomical Context for Thyroid Lymphoma

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34MalaCards
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MalaCards organs/tissues related to Thyroid Lymphoma:

34
Thyroid, B cells, Colon, T cells

Animal Models for Thyroid Lymphoma or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Thyroid Lymphoma:

38 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.1TP53, FAS, BCL2, CDKN2A
2MP:00053918.7TNF, TP53, TP73, FAS, BCL2, CDKN2A
3MP:00053818.5TNF, TP53, TP73, FAS, FOXP1, BCL2
4MP:00053698.4TNF, TP53, FOXP1, MAPK1, BCL2, CDKN2A
5MP:00107718.4TNF, TP53, FAS, MAPK1, BCL2, CDKN2A
6MP:00053888.2TNF, TP53, TP73, FAS, FOXP1, MAPK1
7MP:00053828.2TNF, TP53, TP73, FAS, SSBP3, BCL2
8MP:00053708.2PICALM, TNF, TP53, FAS, MAPK1, CDK1
9MP:00053908.1CDKN2A, SSBP3, FAS, TP73, TP53, TNF
10MP:00053798.0TNF, TP53, TP73, FAS, BCL2, CDK1
11MP:00053857.9TNF, TP53, TP73, FAS, FOXP1, MAPK1
12MP:00020067.7TNF, TP53, TP73, FAS, MAPK1, BCL2
13MP:00053897.7TNF, TP53, TP73, FAS, MAPK1, BCL2
14MP:00053767.1PICALM, TNF, TP53, TP73, FAS, FOXP1
15MP:00036317.1EBF3, TNF, TP53, TP73, FAS, SSBP3
16MP:00053787.1PICALM, TNF, TP53, TP73, FAS, SSBP3
17MP:00053977.0CDKN2B, PICALM, TNF, TP53, TP73, FAS
18MP:00053877.0FOXP1, FAS, TP73, TP53, TNF, PICALM
19MP:00053806.9PICALM, TNF, TP53, TP73, SSBP3, FOXP1
20MP:00053846.6FOXP1, FAS, TP73, TP53, TNF, PICALM
21MP:00107685.1FAS, TP73, TP53, TNF, EBF3, PICALM

Publications for Thyroid Lymphoma

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53PubMed
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Articles related to Thyroid Lymphoma:

(show top 50)    (show all 146)
idTitleAuthorsYear
1
A rare coexistence of thyroid lymphoma with papillary thyroid carcinoma. (24005594)
2013
2
Is 18F-FDG PET/CT useful for distinguishing between primary thyroid lymphoma and chronic thyroiditis? (23816945)
2013
3
Thyroid lymphoma incidentally detected by 18F-fluorocholine (FCH) PET/CT. (23856826)
2013
4
Importance of core biopsy in the diagnosis of thyroid lymphoma. (22507512)
2012
5
Primary mucosa-associated lymphoid tissue thyroid lymphoma: a rare thyroid neoplasm of extrathyroid origin. (22532918)
2012
6
Thyroid lymphoma: acute presentation and long-term outcome. (21835073)
2011
7
Fluorodeoxyglucose positron emission tomography in primary thyroid lymphoma with coexisting lymphocytic thyroiditis. (21875367)
2011
8
Untreated primary thyroid lymphoma in an elderly woman. (21727773)
2011
9
Primary thyroid lymphoma with elevated free thyroxine level. (21947158)
2011
10
Primary thyroid lymphoma (correction of lympoma): diagnostic and therapeutic dilemmas. (20620043)
2010
11
Thyroid Lymphoma as a Cause of Dysphagia and Dyspnea in a Patient without Palpable Nodules or Goiter. (19841755)
2009
12
Surgical treatment of primitive thyroid lymphoma. (20210235)
2009
13
Thyroid lymphoma: a rare tumor requiring combined management. (19671521)
2009
14
Thyroid lymphoma: beyond antigen stimulation. (19128828)
2009
15
Surgical trends in the management of thyroid lymphoma. (17604588)
2008
16
Thyroid lymphoma: early clinical suspicion may be critical for cure. (18852536)
2008
17
An evidence-based approach to the treatment of thyroid lymphoma. (17235456)
2007
18
FDG PET/CT for assessing therapy response in primary thyroid lymphoma. (17242576)
2007
19
HLA associations, microsatellite instability and epigenetic changes in thyroid lymphoma in Chinese. (17454594)
2007
20
High incidence of mucosa-associated lymphoid tissue in primary thyroid lymphoma: a clinicopathologic study of 18 cases in the Korean population. (17071486)
2006
21
Primary thyroid lymphoma mimicking subacute thyroiditis. (17152291)
2006
22
Anaplastic thyroid carcinoma, thyroid lymphoma, and metastasis to thyroid. (16882503)
2006
23
Anaplastic thyroid cancer and primary thyroid lymphoma: a review of these rare thyroid malignancies. (17131397)
2006
24
Fine needle aspiration cytology of primary thyroid lymphoma: a report of ten cases. (16336672)
2005
25
The incidence of primary thyroid lymphoma in thyroid malignancies. (16010091)
2004
26
Mucosa-associated lymphoid tissue thyroid lymphoma: a rare and not aggressive tumour. (12666700)
2002
27
Primary thyroid lymphoma is a heterogeneous disease. (11788631)
2002
28
Two unusual sites of colon cancer metastases and a rare thyroid lymphoma. Case 2. Chemotherapy-responsive right artial metastasis from colon carcinoma. (11481366)
2001
29
Frequent mutations of Fas gene in thyroid lymphoma. (11245438)
2001
30
A reassessment of primary thyroid lymphoma: high-grade MALT-type lymphoma as a distinct subtype of diffuse large B-cell lymphoma. (10931213)
2000
31
Down's syndrome with mucosa-associated lymphoid tissue, thyroid lymphoma and cerebral infarction. (10746421)
2000
32
Expression of interleukin-7 and its receptor in thyroid lymphoma. (11045564)
2000
33
Primary thyroid lymphoma. (10375088)
1999
34
Acute airway obstruction due to primary thyroid lymphoma. (9102733)
1996
35
Lethal tracheal dissolution during treatment for thyroid lymphoma. (7491567)
1995
36
Immunohistochemical detection of p53 and Bcl-2 proteins in Hashimoto's thyroiditis and primary thyroid lymphomas. (7730485)
1995
37
Immunologic type of thyroid lymphoma in an adult T-cell leukemia endemic area in Japan. (8580806)
1995
38
Thyroid lymphoma. The case for combined modality therapy. (8275426)
1994
39
Primary thyroid lymphoma: clinical features, treatment and outcome: a report of 8 cases. (8052462)
1994
40
The significance of MALT histology in thyroid lymphoma: a review of patients from the BNLI and Royal Marsden Hospital. (7826922)
1994
41
Monoclonal gammopathy as a clue to the presence of thyroid lymphoma associated with auto-immune thyroiditis. (1445050)
1992
42
MR imaging in patients with primary thyroid lymphoma. (1636536)
1992
43
Hashimoto's thyroiditis as a risk factor of thyroid lymphoma. (2220394)
1990
44
Hashimoto's disease, thyroid lymphoma and splenic atrophy. (2484910)
1989
45
Thyroid lymphoma. (2804581)
1989
46
MR imaging of primary thyroid lymphoma. (2723189)
1989
47
Laryngeal oedema complicating thyroid lymphoma. (3199019)
1988
48
Ultrasonography in the diagnosis of thyroid lymphoma. (3910657)
1985
49
Radiotherapeutic management of primary thyroid lymphoma. (3918965)
1985
50
Thyroid lymphoma in a patient with hyperthyroidism. (6702880)
1984

Variations for Thyroid Lymphoma

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Expression for genes affiliated with Thyroid Lymphoma

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Thyroid Lymphoma

Search GEO for disease gene expression data for Thyroid Lymphoma.

Pathways for genes affiliated with Thyroid Lymphoma

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Sources:
51PathCards, 55R&D Systems, 54QIAGEN, 39NCBI BioSystems Database, 56Reactome, 61Thomson Reuters, 31KEGG, 58SinoBiological, 5Cell Signaling Technology
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Pathways related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 100)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7IL7R, IL7, BCL2
29.5TP73, BCL2, TNF
3
Show member pathways
9.5FAS, BCL2, TNF
49.4BCL2, MAPK1, TNF
59.3CCNA2, TP53, CCNB1
6
Show member pathways
ATM Signaling Pathway39
9.3CCNB1, TP53, TP73
79.2TP53, MAPK1, CDKN2B, CDKN2A
8
Show member pathways
9.2CDKN2A, TP73, TP53, BCL2
9
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation61
9.2CDKN2B, CDK1, CCNA2, CDKN2A
10
Show member pathways
Apoptosis and survival Apoptotic TNF family pathways61
9.1BCL2, FAS, TNF, TP53
119.1CDKN2A, TP53, MAPK1, BCL2
12
Show member pathways
9.1CCNB1, CCNA2, CDK1
139.1CCNA2, CCNB1, CDK1
14
Show member pathways
IL-9 Signaling Pathway39
Development Thrombopoietin regulated cell processes61
IL-7 Signaling Pathway39
Immune response IL 9 signaling pathway61
9.1TNF, CCNA2, IL7, IL7R, MAPK1
15
Show member pathways
Alzheimers Disease39
9.1TNF, TP53, FAS, MAPK1
16
Show member pathways
9.1IL7, CDK1, MAPK1, IL7R
17
Show member pathways
9.0CDKN2A, TP53, CCNA2, MAPK1, CDKN2B
189.0TP53, IL7, MAPK1, IL7R, BCL2
19
Show member pathways
8.9CDK1, TP53, CCNB1
20
Show member pathways
Signaling Pathways in Glioblastoma39
8.9BCL2, CDKN2A, MAPK1, TP53, CDKN2B
21
Show member pathways
8.8TP53, CCNA2, CCNB1, CDKN2A, CDKN2B
228.8BCL2, MAPK1, FOXP1, CDKN2A, TP53
23
Show member pathways
Prostate Cancer39
Integrated Cancer pathway39
Steroid Biosynthesis39
8.8BCL2, CDK1, TP53, MAPK1
24
Show member pathways
Apoptosis and survival TNFR1 signaling pathway61
TWEAK Signaling Pathway39
Apoptosis Modulation by HSP7039
HIV-1 Nef- Negative effector of Fas and TNF-alpha39
8.8FAS, MAPK1, TNF, TP53, BCL2
25
Show member pathways
8.8FAS, TNF, TP53, MAPK1, BCL2
26
Show member pathways
8.8MAPK1, FAS, TP53, TNF, BCL2
27
Show member pathways
Cell cycle ESR1 regulation of G1 S transition61
Immune response MIF JAB1 signaling61
Cell cycle Cell cycle generic schema 61
8.8CCNB1, MAPK1, CDK1, CCNA2
28
Show member pathways
8.8CCNA2, CCNB1, MAPK1, CDK1
29
Show member pathways
PLK2 and PLK4 events39
Polo-like kinase signaling events in the cell cycle39
8.8CCNG2, CDKN2B, MAPK1, IL7R, CCNB1
308.7TP53, TP73, CCNB1, FAS, BCL2
318.7MAPK1, CDK1, TNF, TP53
328.7TP53, CDK1, CCNB1, CCNA2
338.7TP53, MAPK1, FAS, CDKN2B, CDKN2A, BCL2
34
Show member pathways
8.6BCL2, MAPK1, IL7R, IL7, TP53, TNF
35
Show member pathways
Apoptosis Modulation and Signaling39
Apoptosis39
8.6BCL2, TNF, TP53, TP73, FAS, CDKN2A
36
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
8.6MAPK1, BCL2, CCNA2, TP53, TNF, FAS
37
Show member pathways
DNA damage response (only ATM dependent)39
Wnt Signaling Pathway and Pluripotency39
8.4TP53, TP73, MAPK1, BCL2, CCNG2, CDKN2A
388.4CDK1, MAPK1, CCNA2, CDKN2B, TP53, CDKN2A
398.4CDKN2B, FAS, BCL2, MAPK1, CCNA2, TNF
40
Show member pathways
8.3TP53, FAS, IL7, BCL2, MAPK1, TNF
41
Show member pathways
Development EGFR signaling via PIP361
Development PDGF signaling via MAPK cascades61
Apoptosis and survival Anti apoptotic action of membrane bound ESR161
Signaling of Hepatocyte Growth Factor Receptor39
Development EGFR signaling via small GTPases61
Development Neurotrophin family signaling61
Apoptosis and survival NGF signaling pathway61
Apoptosis and survival Role of CDK5 in neuronal death and survival61
8.3TP53, FAS, CDK1, TP73, BCL2, MAPK1
42
Show member pathways
8.2TP53, CDK1, MAPK1, FAS, TNF, TP73
43
Show member pathways
Cell cycle39
8.2CDKN2A, CDK1, CDKN2B, CCNB1, CCNA2, TP53
44
Show member pathways
8.2CCNA2, CCNB1, MAPK1, BCL2, CDKN2A, CDKN2B
45
Show member pathways
8.2CCNB1, CDK1, CCNA2, TP73, TP53, CDKN2A
46
Show member pathways
8.1BCL2, IL7, TNF, TP53, IL7R, CDKN2B
47
Show member pathways
7.9TP53, CDKN2B, CDKN2A, CCNB1, MAPK1, CCNA2
48
Show member pathways
7.8CDKN2B, TP53, CCNA2, CCNB1, CCNG2, CDK1
49
Show member pathways
Proteasome Degradation39
Immune response Antigen presentation by MHC class I61
7.8TNF, TP53, CCNB1, BCL2, CDK1, FAS
50
Show member pathways
DNA damage response39
7.7CCNG2, CDK1, CDKN2A, FAS, TP53, CCNB1

Compounds for genes affiliated with Thyroid Lymphoma

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Sources:
46Novoseek, 12DrugBank, 52PharmGKB, 62Tocris Bioscience, 25HMDB, 30IUPHAR, 3BitterDB
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Compounds related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 151)
idCompoundScoreTop Affiliating Genes
1depsipeptide469.3FAS, CCNA2, BCL2, CDKN2A, TP53
2noxa469.2BCL2, FAS, TP73, TP53
3o6-methylguanine469.2CDKN2B, TP73, TP53, CDKN2A
4sulforaphane469.1MAPK1, FAS, BCL2, CCNA2, CCNB1
5c2ceramide468.9TP53, TNF, BCL2, MAPK1, FAS
6flavopiridol46 129.9CDKN2A, CDK1, BCL2, CCNA2, TP53
7vincristine46 52 1210.8BCL2, TP53, CDKN2A, CCNA2, CCNB1, TP73
8egcg468.8TNF, CDKN2A, BCL2, MAPK1, FAS, TP53
9thymidylate468.7FAS, CCNA2, TP53, CDK1, BCL2, CDKN2A
10cytarabine46 52 1210.6TP53, BCL2, FAS, CDKN2B, CDKN2A, CCNA2
11ceramide468.5CDK1, MAPK1, CCNA2, FAS, TNF, BCL2
12hydroxyurea46 52 1210.5TP53, CCNB1, CDKN2A, CCNA2, CDK1
13vinblastine46 52 1210.5CCNB1, CDK1, BCL2, CCNA2, TP53
145fluorouracil468.5BCL2, TP53, TP73, FAS, CCNA2, CDK1
15actinomycin d468.5BCL2, TP53, MAPK1, CDKN2A, FAS, TNF
16docetaxel46 52 62 1211.4TP53, CCNA2, CCNB1, BCL2, CDK1, CDKN2A
17adriamycin468.2FAS, TP53, CCNB1, BCL2, CDK1, CDKN2A
18ly294002468.2BCL2, CDK1, TNF, FAS, MAPK1, TP53
19olomoucine46 129.2TP53, CCNB1, CCNA2, MAPK1, BCL2, CDK1
20n acetylcysteine468.2MAPK1, FAS, TNF, TP53, BCL2, CDK1
21roscovitine468.2CCNA2, MAPK1, TP53, CDKN2A, CDK1, BCL2
22resveratrol46 62 25 1211.2CCNA2, FAS, BCL2, TP53, CCNB1, MAPK1
23mg 13246 629.2TNF, CDKN2A, TP53, FAS, CCNA2, CCNB1
24lactacystin468.1BCL2, TP53, CCNA2, CCNB1, MAPK1, CDK1
25camptothecin46 62 1210.0TP73, CCNA2, TP53, FAS, BCL2, CCNB1
26pd 98,059468.0TNF, CDKN2B, CDK1, BCL2, MAPK1, CCNB1
27paraffin468.0CDK1, BCL2, CCNB1, CCNA2, TP73, TP53
28progesterone46 30 62 25 1211.9TP53, CCNB1, CDKN2A, TP73, CDK1, CCNA2
29paclitaxel46 52 129.9FAS, CDKN2A, CDK1, BCL2, MAPK1, CCNB1
30rapamycin467.9CDK1, BCL2, FAS, IL7, CCNA2, CCNG2
31adpribose467.9CDK1, BCL2, CCNA2, FAS, TP53, TNF
32sp 60012546 628.9CDK1, BCL2, MAPK1, CCNB1, CCNA2, FAS
33thymidine46 258.8CDK1, TNF, TP53, FAS, CCNA2, MAPK1
34etoposide46 52 62 1210.8CCNA2, FAS, TP53, BCL2, CDK1, CCNB1
35sb 20358046 628.8TNF, TP53, FAS, CCNA2, CCNB1, MAPK1
36cycloheximide467.8MAPK1, TP53, FAS, TNF, IL7, CDKN2A
37doxorubicin46 52 129.8CCNA2, TP73, CCNB1, IL7, TP53, BCL2
38arsenite46 258.8MAPK1, TP53, FAS, CCNA2, CDKN2B, CCNB1
39genistein46 30 62 3 25 1212.7IL7, FAS, BCL2, TNF, CDKN2A, CDK1
40oxygen46 258.6TNF, CCNB1, CDK1, BCL2, IL7, CCNA2
41butyrate467.6CCNB1, MAPK1, BCL2, CDK1, CDKN2A, CCNA2
42oligonucleotide467.5SSBP3, IL7, CCNA2, CCNB1, BCL2, TP53
43h2o2467.5MAPK1, CDKN2A, CDK1, BCL2, CCNB1, CCNA2
44tyrosine467.4CDKN2B, CDK1, RHOH, MAPK1, IL7R, CCNB1
45threonine467.3SSBP3, CDK1, MAPK1, CCNB1, CCNA2, TP73
46vegf467.1IL7, CCNB1, BCL2, CDK1, TP73, TP53
47cisplatin46 52 62 129.9CDKN2A, CDK1, BCL2, CCNB1, CCNA2, MAPK1
48serine466.3CCNA2, CCNB1, IL7, CDK1, TNF, MAPK1
49estrogen466.2IL7, MAPK1, CDKN2B, CDKN2A, CDK1, CCNG2
50retinoic acid46 257.1TNF, CDKN2B, CDKN2A, CDK1, TP53, TP73

GO Terms for genes affiliated with Thyroid Lymphoma

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Sources:
17Gene Ontology
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Cellular components related to Thyroid Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056548.1CCNA2, CCNB1, MAPK1, CDK1, CDKN2A, TP53
2cytosolGO:0058296.8TP53, TP73, FAS, CCNB1, MAPK1, BCL2
3cytoplasmGO:0057376.2CCNB1, CCNA2, FOXP1, FAS, TP53, CCNG2
4nucleusGO:0056345.1CDKN2B, PICALM, EBF3, TP53, TP73, FAS

Biological processes related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idNameGO IDScoreTop Affiliating Genes
1immunoglobulin productionGO:00237710.4FAS, IL7R
2regulation of G2/M transition of mitotic cell cycleGO:01038910.3CDKN2A, CCNA2
3renal system processGO:00301410.2BCL2, FAS
4negative regulation of phosphorylationGO:04232610.2RHOH, CDKN2A, CDKN2B
5T cell lineage commitmentGO:00236010.2IL7, TP53
6necroptotic signaling pathwayGO:09752710.2FAS, TNF
7transformed cell apoptotic processGO:00692710.2FAS, TNF
8spleen developmentGO:04853610.1FAS, BCL2, CDKN2B
9B cell lineage commitmentGO:00232610.1BCL2, TP53
10mitotic G1 DNA damage checkpointGO:03157110.1TP53, TP73
11replicative senescenceGO:09039910.0TP53, CDKN2A
12negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.0BCL2, IL7, TNF
13regulation of protein stabilityGO:0316479.9MAPK1, BCL2, CDKN2A
14release of cytochrome c from mitochondriaGO:0018369.9TP53, TP73, BCL2
15response to gamma radiationGO:0103329.9TP53, TP73, BCL2
16extrinsic apoptotic signaling pathway via death domain receptorsGO:0086259.9BCL2, FAS, TNF
17humoral immune responseGO:0069599.9TNF, IL7, BCL2
18intrinsic apoptotic signaling pathway in response to DNA damageGO:0086309.9TNF, TP73, BCL2
19regulation of cyclin-dependent protein serine/threonine kinase activityGO:0000799.9CDKN2B, CCNB1, CCNA2
20regulation of mitochondrial membrane permeabilityGO:0469029.9TP53, BCL2
21activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.9TNF, FAS, CDKN2A
22mitotic G2 DNA damage checkpointGO:0070959.9CCNA2, CDK1
23response to glucocorticoidGO:0513849.9BCL2, FAS, TNF
24cell cycle checkpointGO:0000759.9CDKN2A, CCNG2
25DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:0069789.8TP53, TP73
26organ morphogenesisGO:0098879.8MAPK1, IL7, TNF
27cell cycle arrestGO:0070509.8CDKN2B, CDKN2A, TP73, TP53
28response to salt stressGO:0096519.8TNF, TP53
29digestive tract morphogenesisGO:0485469.6BCL2, TP73
30cellular response to DNA damage stimulusGO:0069749.6TP53, TP73, MAPK1, BCL2
31cell agingGO:0075699.6CDK1, BCL2, TP53
32peptidyl-serine phosphorylationGO:0181059.5CDK1, BCL2, MAPK1
33ventricular cardiac muscle cell developmentGO:0550159.5CCNB1, CDK1
34cellular response to hypoxiaGO:0714569.5BCL2, CCNB1, TP53
35positive regulation of apoptotic processGO:0430659.5TNF, TP53, TP73, FAS
36MAPK cascadeGO:0001659.5TNF, MAPK1, CDK1
37negative regulation of cell growthGO:0303089.5CDKN2A, BCL2, TP53
38response to toxic substanceGO:0096369.4FAS, MAPK1, BCL2, CDK1
39activation of MAPK activityGO:0001879.3CDK1, MAPK1, TP73, TNF
40G2/M transition of mitotic cell cycleGO:0000869.3CCNA2, CCNB1, CDK1, CDKN2B
41negative regulation of cell proliferationGO:0082859.1TNF, TP53, CDKN2A, CDKN2B
42Ras protein signal transductionGO:0072659.0TP53, CCNA2, MAPK1, CDK1, CDKN2A
43mitotic cell cycleGO:0002789.0CDKN2B, CDKN2A, CDK1, CCNB1, CCNA2
44negative regulation of apoptotic processGO:0430669.0TP53, FAS, IL7, BCL2, CDK1
45response to drugGO:0424938.9TNF, CCNB1, BCL2, CDK1
46apoptotic processGO:0069158.6TNF, TP53, FAS, MAPK1, BCL2, CDK1
47positive regulation of transcription from RNA polymerase II promoterGO:0459448.6TNF, TP53, TP73, SSBP3, CDKN2A, CDKN2B
48positive regulation of transcription, DNA-templatedGO:0458938.3PICALM, EBF3, TNF, TP53, TP73, CCNA2
49transcription, DNA-templatedGO:0063518.1EBF3, TP73, SSBP3, FOXP1, MAPK1, CDKN2A
50protein complex assemblyGO:0064618.0CDK1, PICALM, TP53, FAS, SSBP3, CCNB1

Molecular functions related to Thyroid Lymphoma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.9CDKN2A, CDKN2B
2MDM2/MDM4 family protein bindingGO:0973719.9TP53, CDKN2A
3protein phosphatase 2A bindingGO:0517219.7BCL2, TP53
4p53 bindingGO:0020399.7CDKN2A, TP73, TP53
5protease bindingGO:0020209.4BCL2, TP53, TNF
6RNA polymerase II carboxy-terminal domain kinase activityGO:0083539.2CDK1, MAPK1
7transcription factor bindingGO:0081349.1TP53, TP73, MAPK1, BCL2, CDKN2A
8identical protein bindingGO:0428029.0TNF, TP53, TP73, FAS, BCL2
9protein kinase bindingGO:0199018.8TP53, TP73, CCNA2, CCNB1, CDKN2A, CDKN2B
10protein bindingGO:0055156.0CDKN2B, PICALM, TNF, TP53, TP73, FAS

Products for genes affiliated with Thyroid Lymphoma

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Sources for Thyroid Lymphoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet