Aliases & Classifications for Thyrotoxicosis

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Summaries for Thyrotoxicosis

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Wikipedia:63 Hyperthyroidism, also known as overactive thyroid and hyperthyreosis, is a condition in which the... more...

MalaCards based summary: Thyrotoxicosis is related to neonatal thyrotoxicosis and thyroiditis. An important gene associated with Thyrotoxicosis is TSHR (thyroid stimulating hormone receptor), and among its related pathways are G alpha (s) signalling events and Hormone ligand-binding receptors. The drugs potassium iodide and thyroglobulin and the compounds sodium iodide and asparagine have been mentioned in the context of this disorder. Affiliated tissues include thyroid, heart and pituitary, and related mouse phenotypes are hearing/vestibular/ear and reproductive system.

Disease Ontology:9 A thyroid gland disease that is characterized by excess thyroid hormone.

Related Diseases for Thyrotoxicosis

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Diseases related to Thyrotoxicosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 186)
idRelated DiseaseScoreTop Affiliating Genes
1neonatal thyrotoxicosis31.6LHX3, TSHR
2thyroiditis31.4TG, TSHR, CGA
3hypothyroidism31.0TG, TSHR
4myxedema30.8TSHR, TG
5subacute thyroiditis30.8TSHR, TG
6multinodular goiter30.7TSHR, TG
7endemic goiter30.6TG, TSHR
8graves' disease30.5CGA, TSHR, DIO2, TG
9hypopituitarism30.5LHX3, CGA
10nodular goiter30.5TG, TSHR
11thyroid cancer30.4TSHR, TG, TXNRD2
12goiter30.4DIO2, TSHR, TG, TXNRD2
13toxic diffuse goiter30.4TG, TSHR
14struma ovarii30.4TG, TSHR
15nontoxic goiter30.1TG, TSHR
16hyperthyroidism30.1TXNRD2, TG, TSHR, DIO2, CGA
17thyroid hormone resistance30.1TXNRD2, TG
18papillary carcinoma29.9TG, TSHR
19infertility29.8TXNRD2, CGA
20thyroid adenoma29.7TSHR, DIO2, TG, TXNRD2
21adenoma29.6TXNRD2, TG, TSHR, DIO2, CGA
22suppurative thyroiditis10.4
23pendred syndrome10.4TG
24exophthalmos10.3
25hepatitis10.3
26atrial fibrillation10.2
27thymic hyperplasia10.2
28hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia10.2TSHR, TG
29thyroid carcinoma, follicular10.2TG, TSHR
30pulmonary hypertension10.2
31cerebritis10.2
32thyroid carcinoma, papillary10.2TSHR, TG
33precocious puberty10.2TSHR, CGA
34congenital hypothyroidism10.2TG, TSHR
35gestational trophoblastic neoplasm10.2TSHR, CGA
36kallmann syndrome10.2CGA, LHX3
37thyroid cancer, anaplastic10.2TSHR, TG
38myocardial infarction10.2
39pituitary apoplexy10.2
40pernicious anemia10.2
41exophthalmic ophthalmoplegia10.2
42ophthalmoplegia10.2
43thyrotoxic periodic paralysis10.2
44turner syndrome10.1CGA, TG
45hashimoto thyroiditis10.1TG, TSHR
46congestive heart failure10.1
47myasthenia gravis10.1
48autoimmune thyroiditis10.1
49hepatitis c10.1
50periarthritis10.1

Graphical network of the top 20 diseases related to Thyrotoxicosis:



Diseases related to thyrotoxicosis

Symptoms for Thyrotoxicosis

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Drugs & Therapeutics for Thyrotoxicosis

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Genetic Tests for Thyrotoxicosis

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Anatomical Context for Thyrotoxicosis

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MalaCards organs/tissues related to Thyrotoxicosis:

31
Thyroid, Heart, Pituitary, Bone, Testes, Liver, Brain, Bone marrow, Temporal lobe

Animal Models for Thyrotoxicosis or affiliated genes

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MGI Mouse Phenotypes related to Thyrotoxicosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053778.6HCN2, LHX3, TSHR
2MP:00053898.3HCN2, LHX3, TSHR, CGA
3MP:00053798.1LHX3, TG, TSHR, DIO2, CGA
4MP:00036317.5HCN2, LHX3, TXNRD2, TG, CGA, TSHR
5MP:00053767.5LHX3, TXNRD2, TG, TSHR, DIO2, CGA
6MP:00053787.2HCN2, LHX3, TG, TSHR, DIO2, CGA

Publications for Thyrotoxicosis

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Articles related to Thyrotoxicosis:

(show top 50)    (show all 717)
idTitleAuthorsYear
1
A 27-year-old woman presenting with refractory hypoxaemic respiratory failure, haemoptysis and thyrotoxicosis: a rare manifestation of propylthiouracil therapy. (25150234)
2014
2
Management of severe amiodarone-induced thyrotoxicosis after failure of standard medical treatment. (23540613)
2013
3
Hypokalemic periodic paralysis as first sign of thyrotoxicosis. (23599824)
2013
4
Increased sex hormone-binding globulin levels in children and adolescents with thyrotoxicosis. (23548728)
2013
5
Body mass index and the development of amiodarone-induced thyrotoxicosis in adults with congenital heart disease--a cohort study. (22386642)
2013
6
Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis. (22837931)
2012
7
Gynaecomastia as the initial presentation of thyrotoxicosis. (23565425)
2012
8
Total thyroidectomy for amiodarone-associated thyrotoxicosis: should surgery always be delayed for pre-operative medical preparation? (22613770)
2012
9
Thyrotoxicosis presenting as acute bulbar palsy. (21751598)
2011
10
Takotsubo cardiomyopathy in association with endogenous and exogenous thyrotoxicosis. (20551140)
2011
11
The association of insulin resistance with subclinical thyrotoxicosis. (21834678)
2011
12
Resistant thyrotoxicosis in a patient with graves disease: a case report. (21845211)
2011
13
Thyrotoxicosis. (21819001)
2011
14
Takotsubo cardiomyopathy precipitated by thyrotoxicosis. (21054211)
2010
15
Repetitive monomorphic ventricular tachycardia as a manifestation of suboptimally treated thyrotoxicosis. (22022738)
2010
16
Thyrotoxicosis factitia induces Takotsubo cardiomyopathy in end-stage renal disease: a pathogenetic hypothesis. (20150943)
2010
17
The correlation between left ventricular failure and right ventricular systolic dysfunction occurring in thyrotoxicosis. (20589198)
2010
18
A case of Takotsubo cardiomyopathy in a patient with iatrogenic thyrotoxicosis. (19628289)
2010
19
Iodinated contrast prior to evaluation for thyrotoxicosis. (19263484)
2009
20
A Case of Amiodarone-Induced Thyrotoxicosis: A diagnostic and therapeutic dilemma. (21509317)
2009
21
High iodine (substrate) turnover Graves' disease: the intriguing 'rapid responder' variant of thyrotoxicosis. (18941129)
2008
22
Cerebral sinus venous thrombosis in a subject with thyrotoxicosis and MTHFR gene polymorphism. (18941937)
2008
23
Uterine choriocarcinoma accompanied by an extremely high human chorionic gonadotropin level and thyrotoxicosis. (18412797)
2008
24
Persistent neonatal thyrotoxicosis in a neonate secondary to a rare thyroid-stimulating hormone receptor activating mutation: case report and literature review. (18558604)
2008
25
Impact of thyroid metabolism on the course of INR levels in a patient with systemic anticoagulation suffering from amiodarone-induced thyrotoxicosis. (17943696)
2007
26
Tailor treatment to the patient in thyrotoxicosis. (17784663)
2007
27
Thyrotoxicosis with coronary spasm that required coronary artery bypass surgery. (18057764)
2007
28
Amiodarone-induced thyrotoxicosis: clinical course and predictors of outcome. (17572251)
2007
29
Management of amiodarone-induced thyrotoxicosis in Latin America: an electronic survey. (16984234)
2006
30
Cardiomyopathy and thyrotoxicosis: tachycardiomyopathy or thyrotoxic cardiomyopathy? (16485742)
2006
31
A cluster of thyrotoxicosis associated with consumption of a soy milk product. (16366059)
2005
32
Secondary osteoporosis: thyrotoxicosis, rheumatoid arthritis, and diabetes mellitus. (15221485)
2004
33
Contrast-induced thyrotoxicosis. (15332308)
2004
34
Recurrent gestational thyrotoxicosis presenting as recurrent hyperemesis gravidarum--report of two cases. (15763786)
2004
35
Fulminant hepatic failure in a patient with inactive HBsAg carrier state, acute hepatitis E and thyrotoxicosis. (14585402)
2003
36
Hypercalcemia in hyperthyroidism: patterns of serum calcium, parathyroid hormone, and 1,25-dihydroxyvitamin D3 levels during management of thyrotoxicosis. (14715479)
2003
37
Thyrotoxicosis--surgical management in the era of evidence-based medicine: experience in western India with 752 cases. (12471001)
2002
38
Association between diabetic ketoacidosis and thyrotoxicosis. (12486499)
2002
39
McCune-Albright syndrome with thyrotoxicosis. (11564936)
2001
40
Graves' hyperthyroidism following transient thyrotoxicosis during interferon therapy for chronic hepatitis type C. (7718983)
1995
41
Thyrotoxicosis and hungry bone syndrome--a cause of posttreatment hypocalcemia. (8200118)
1994
42
Thyrotoxicosis presenting as generalized pruritic exfoliative dermatitis and fever. (1386765)
1992
43
Choriogonadotropin-mediated thyrotoxicosis in a man. (2049833)
1991
44
Neonatal thyrotoxicosis treated with exchange transfusion and Lugol's iodine. (2859196)
1985
45
Effects of L-thyroxine treatment on pituitary GH content of adult rats with neonatal thyrotoxicosis. (6637335)
1983
46
Neonatal thyrotoxicosis in four siblings born to a previously thyrotoxic mother. (717342)
1978
47
Concomitant pernicious anemia and thyrotoxicosis. A case report and discussion. (5409998)
1970
48
Thyrotoxicosis and gigantism associated with "Klinefelter's syndrome". (5850468)
1965
49
Neonatal thyrotoxicosis. (13731873)
1960
50
Uropepsin excretion in neurocirculatory asthenia and thyrotoxicosis. (13381999)
1956

Variations for Thyrotoxicosis

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Expression for genes affiliated with Thyrotoxicosis

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Search GEO for disease gene expression data for Thyrotoxicosis.

Pathways for genes affiliated with Thyrotoxicosis

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Compounds for genes affiliated with Thyrotoxicosis

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Sources:
43Novoseek, 24HMDB, 28IUPHAR, 12DrugBank, 2BitterDB, 49PharmGKB
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Compounds related to Thyrotoxicosis according to GeneCards Suite gene sharing:

(show all 38)
idCompoundScoreTop Affiliating Genes
1sodium iodide439.9TG, TSHR
2asparagine439.8TXNRD2, TSHR
3cytosine43 2410.8TSHR, TXNRD2
4prednisolone43 28 1211.7TSHR, TG
5selenocysteine43 24 1211.7DIO2, TXNRD2
6carbohydrates439.6TSHR, TG
7guanine43 24 1211.5TSHR, TG, TXNRD2
8sialic acid439.4CGA, TG, TSHR
9thymidine43 2410.4TSHR, TXNRD2, TG
10paraffin439.4CGA, TSHR, TG
11propylthiouracil43 2 1211.4TSHR, DIO2, TG
12iodine43 2410.4TSHR, DIO2, TG
13125i439.4DIO2, TSHR, TG
14iodide43 2410.4TSHR, DIO2, TG
15methimazole43 2 1211.4TG, DIO2, TSHR
16adenine43 24 1211.3TSHR, TXNRD2
17carbachol43 28 1211.3CGA, TG
18adenylate439.3CGA, TSHR, TG
19forskolin43 49 1211.3TSHR, CGA, DIO2
20selenium43 2410.3TG, DIO2, TXNRD2
21h2o2439.2CGA, TG, TXNRD2
22vegf439.2CGA, TSHR, TG
23threonine439.1TXNRD2, TSHR, DIO2
24glutamate439.1TSHR, TG, CGA
25cycloheximide439.0CGA, DIO2, TG
26sodium43 2410.0HCN2, TG, TSHR
27cyclic amp43 2410.0HCN2, TSHR, CGA
28aspartate439.0TG, TSHR, TXNRD2, CGA
29arginine438.9TSHR, CGA, TXNRD2, TG
30retinoic acid43 249.8DIO2, TSHR, TXNRD2, TG
31ribonucleic acid438.8TG, TSHR, DIO2, CGA
32tyrosine438.4TSHR, TXNRD2, LHX3, DIO2, TG
33triiodothyronine438.4CGA, TXNRD2, TG, TSHR, DIO2
34thyroxine43 249.4CGA, TSHR, DIO2, TXNRD2, TG
35alanine438.4CGA, TSHR, TG, TXNRD2, DIO2
36estrogen438.4TXNRD2, TSHR, TG, DIO2, CGA
37serine438.3CGA, TXNRD2, TG, TSHR, DIO2
38cysteine437.7HCN2, LHX3, TXNRD2, TG, TSHR, DIO2

GO Terms for genes affiliated with Thyrotoxicosis

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Biological processes related to Thyrotoxicosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone biosynthetic processGO:00424469.2DIO2, TG
2thyroid gland developmentGO:00308789.1CGA, TG
3thyroid hormone generationGO:00065908.8CGA, DIO2, TG
4cell-cell signalingGO:00072678.8TSHR, CGA, HCN2

Molecular functions related to Thyrotoxicosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.4CGA, TG

Products for genes affiliated with Thyrotoxicosis

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  • Antibodies
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Sources for Thyrotoxicosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet