MCID: TCK001
MIFTS: 45

Tick-Borne Encephalitis malady

Rare diseases, Neuronal diseases, Infectious diseases, Skin diseases, Immune diseases categories

Aliases & Classifications for Tick-Borne Encephalitis

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Sources:
9Disease Ontology, 41NIH Rare Diseases, 11DISEASES, 43Novoseek, 47Orphanet, 60UMLS, 27ICD9CM, 55SNOMED-CT, 33MeSH, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet
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Tick-Borne Encephalitis, Aliases & Descriptions:

Name: Tick-Borne Encephalitis 9 41 11 47 60
Siberian Tick-Borne Encephalitis 9 60
Dermacentor-Borne Necrosis - Erythema - Lymphadenopathy 47
Western European Tick-Borne Encephalitis 9
Russian Spring-Summer Encephalitis 9
Encephalitis, Far Eastern Russian 60
 
Encephalitis, Central European 60
Central European Encephalitis 9
West-Siberian Encephalitis 9
Encephalitis Tick-Borne 43
Taiga Encephalitis 9
Far Eastern Tbe 9


Classifications:



Characteristics (Orphanet epidemiological data):

47
tick-borne encephalitis:
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age


External Ids:

Disease Ontology9 DOID:0050175
ICD9CM27 063.2
MeSH33 D004675
Orphanet47 297
MESH via Orphanet34 D004675
ICD10 via Orphanet26 A84.0, A84.1, A84.8 A84.9, more
UMLS via Orphanet61 C0014061

Summaries for Tick-Borne Encephalitis

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Disease Ontology:9 A viral infectious disease that results in inflammation located in brain, has material basis in tick-borne encephalitis virus, which is transmitted by ixodes ticks. the infection has symptom drowsiness, has symptom confusion, has symptom sensory disturbances, and has symptom paralysis.

MalaCards based summary: Tick-Borne Encephalitis, also known as siberian tick-borne encephalitis, is related to encephalitis and west nile virus, and has symptoms including drowsiness, confusion and sensory disturbances. An important gene associated with Tick-Borne Encephalitis is OAS1 (2'-5'-oligoadenylate synthetase 1, 40/46kDa), and among its related pathways are NOD-like Receptor Signaling Pathways and Interferon Signaling. The compounds rantes and 2,5-oligoadenylate have been mentioned in the context of this disorder. Affiliated tissues include brain, brain and testes.

Wikipedia:63 Tick-borne encephalitis (TBE) is a viral infectious disease involving the central nervous system. The... more...

Related Diseases for Tick-Borne Encephalitis

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Graphical network of the top 20 diseases related to Tick-Borne Encephalitis:



Diseases related to tick-borne encephalitis

Symptoms for Tick-Borne Encephalitis

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Symptoms:

 9
  • drowsiness
  • confusion
  • sensory disturbances
  • paralysis

Drugs & Therapeutics for Tick-Borne Encephalitis

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Drug clinical trials:

Search ClinicalTrials for Tick-Borne Encephalitis

Search NIH Clinical Center for Tick-Borne Encephalitis

Genetic Tests for Tick-Borne Encephalitis

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Anatomical Context for Tick-Borne Encephalitis

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MalaCards organs/tissues related to Tick-Borne Encephalitis:

31
Brain, Testes, T cells, Spleen, Spinal cord, Kidney, Liver, B cells, Neutrophil

FMA organs/tissues related to Tick-Borne Encephalitis:

14
Brain

Animal Models for Tick-Borne Encephalitis or affiliated genes

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Publications for Tick-Borne Encephalitis

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Articles related to Tick-Borne Encephalitis:

(show top 50)    (show all 548)
idTitleAuthorsYear
1
Influence of altitude on tick-borne encephalitis infection risk in the natural foci of the Altai Republic, Southern Siberia. (25748512)
2015
2
Anti-tick-borne encephalitis (TBE) virus neutralizing antibodies dynamics in natural infections versus vaccination. (25722483)
2015
3
Attenuation of tick-borne encephalitis virus using large-scale random codon re-encoding. (25734338)
2015
4
Cloning and Expression of Recombinant Tick-Borne Encephalitis Virus-like Particles in Pichia pastoris. (25389513)
2014
5
Variation of the specificity of the human antibody responses after tick-borne encephalitis virus infection and vaccination. (25253341)
2014
6
Tick-borne encephalitis virus habitats in North East Germany: reemergence of TBEV in ticks after 15 years of inactivity. (25110671)
2014
7
Tick-borne encephalitis virus, Zealand, Denmark, 2011. (23764123)
2013
8
Tick-borne encephalitis: a disease neglected by travel medicine. (23916617)
2013
9
Tick-borne encephalitis associated with consumption of raw goat milk, Slovenia, 2012. (23697658)
2013
10
Factors associated with seroimmunity against tick borne encephalitis virus 10 years after booster vaccination. (23306371)
2013
11
Low coverage and predictors of vaccination uptake against tick-borne encephalitis in Slovenia. (21398380)
2012
12
ssICAM-1, IL-21 and IL-23 in patients with tick borne encephalitis and neuroborreliosis. (22705151)
2012
13
Peripheral facial palsy in patients with tick-borne encephalitis. (22192120)
2012
14
Age affects quantity but not quality of antibody responses after vaccination with an inactivated flavivirus vaccine against tick-borne encephalitis. (22461903)
2012
15
Isolated meningomyeloradiculitis following infection with tick borne encephalitis virus. (22425461)
2012
16
Prevalence of tick borne encephalitis virus in tick nymphs in relation to climatic factors on the southern coast of Norway. (22913287)
2012
17
Prevalence and molecular characterization of tick-borne encephalitis virus in Ixodes ricinus ticks collected in Slovenia. (21028962)
2011
18
Tick-borne encephalitis in Poland in years 1993-2008--epidemiology and clinical presentation. A retrospective study of 687 patients. (21143706)
2011
19
Needle-free jet injection of DNA and protein vaccine of the far-eastern subtype of tick-borne encephalitis virus induces protective immunity in mice. (22004565)
2011
20
Transcriptional upregulation of SOCS 1 and suppressors of cytokine signaling 3 mRNA in the absence of suppressors of cytokine signaling 2 mRNA after infection with West Nile virus or tick-borne encephalitis virus. (20854017)
2010
21
What tick-borne encephalitis may look like: clinical signs and symptoms. (20970727)
2010
22
Highly specific detection of antibodies to tick-borne encephalitis (TBE) virus in humans using a domain III antigen and a sensitive immune complex (IC) ELISA. (19409841)
2009
23
Safety evaluation of chimeric Langat/Dengue 4 flavivirus, a live vaccine candidate against tick-borne encephalitis. (19697399)
2009
24
First identification of tick-borne encephalitis in Denmark outside of Bornholm, August 2009. (19758543)
2009
25
Alimentary transmission of tick-borne encephalitis in the Czech Republic (1997-2008). (19526924)
2009
26
Spatial and temporal organization of tick-borne encephalitis flavivirus replicated RNA in living cells. (18667221)
2008
27
A newly detected tick-borne encephalitis (TBE) focus in south-east Sweden: a follow-up study of TBE virus (TBEV) seroprevalence. (17852896)
2008
28
Evaluation of the Langat/dengue 4 chimeric virus as a live attenuated tick-borne encephalitis vaccine for safety and immunogenicity in healthy adult volunteers. (18207289)
2008
29
Variable spikes in tick-borne encephalitis incidence in 2006 independent of variable tick abundance but related to weather. (19068106)
2008
30
The prevalence of tick-borne encephalitis in the region of West Bohemia (Czech Republic) between 1960-2005. (18330525)
2008
31
Changes in the metabolic activity of macrophages under the influence of tick-borne encephalitis virus. (17367298)
2007
32
Setting an alert for tick-borne encephalitis. (18026017)
2007
33
Elevated concentration of the chemokine CCL3 (MIP-1alpha) in cerebrospinal fluid and serum of patients with tick borne encephalitis. (17357337)
2006
34
A simple spatial model to explain the distribution of human tick-borne encephalitis cases in hungary. (17187571)
2006
35
Prevalence and incidence of antibodies to Borrelia burgdorferi and to tick-borne encephalitis virus in agricultural and forestry workers from Tuscany, Italy. (15948001)
2005
36
Combined prime-boost vaccination against tick-borne encephalitis (TBE) using a recombinant vaccinia virus and a bacterial plasmid both expressing TBE virus non-structural NS1 protein. (16076390)
2005
37
Humoral and cellular immune response to RNA immunization with flavivirus replicons derived from tick-borne encephalitis virus. (16306582)
2005
38
Attempt to detect evidence for tick-borne encephalitis virus in ticks and mammalian wildlife in The Netherlands. (15815150)
2005
39
A synthetic peptide based on the NS1 non-structural protein of tick-borne encephalitis virus induces a protective immune response against fatal encephalitis in an experimental animal model. (16022903)
2005
40
Tick-borne encephalitis virus infections in Lithuanian domestic animals and ticks. (16191893)
2005
41
Activation of the RIG-I gene, coding for DEXH/D-protein in infection of RH cells by tick-borne encephalitis virus]. (15143669)
2004
42
Characterization of a membrane-associated trimeric low-pH-induced Form of the class II viral fusion protein E from tick-borne encephalitis virus and its crystallization. (14990739)
2004
43
Antibodies to DNA in the blood of patients with tick-borne encephalitis]. (15456145)
2004
44
Long-term immunity after vaccination against tick-borne encephalitis with Encepur using the rapid vaccination schedule. (15146994)
2004
45
Vaccinia virus recombinant expressing gene of tick-borne encephalitis virus non-structural NS1 protein elicits protective activity in mice. (14687719)
2003
46
Fluorescent probing of lymphocyte and erythrocyte plasma membranes in persistence of tick-borne encephalitis virus: monitoring of structural changes. (14631506)
2003
47
Characterisation of human tick-borne encephalitis virus from Sweden. (14556277)
2003
48
Shift of the tick Ixodes ricinus and tick-borne encephalitis to higher altitudes in central Europe. (12736793)
2003
49
Epidemiological, clinical and laboratory distinction between human granulocytic ehrlichiosis and the initial phase of tick-borne encephalitis. (12422617)
2002
50
Tick-borne encephalitis (TBE) in dogs. (12141763)
2002

Variations for Tick-Borne Encephalitis

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Expression for genes affiliated with Tick-Borne Encephalitis

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Search GEO for disease gene expression data for Tick-Borne Encephalitis.

Pathways for genes affiliated with Tick-Borne Encephalitis

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Compounds for genes affiliated with Tick-Borne Encephalitis

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Sources:
43Novoseek
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Compounds related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1rantes439.1CD209, TLR3
22,5-oligoadenylate438.0OAS3, OAS1, OAS2, TLR3

GO Terms for genes affiliated with Tick-Borne Encephalitis

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Cellular components related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1membraneGO:00160208.7CD209, OAS2, TLR3
2cytoplasmGO:00057377.4CD209, OAS3, OAS1, OAS2, TLR3

Biological processes related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1regulation of ribonuclease activityGO:00607009.7OAS3, OAS1
2purine nucleotide biosynthetic processGO:00061649.7OAS1, OAS2
3negative regulation of viral genome replicationGO:00450719.4OAS1, OAS3
4type I interferon signaling pathwayGO:00603379.3OAS2, OAS1, OAS3
5interferon-gamma-mediated signaling pathwayGO:00603339.2OAS2, OAS1, OAS3
6response to virusGO:00096159.2OAS2, OAS1, OAS3
7nucleobase-containing compound metabolic processGO:00061399.2OAS2, OAS3
8cytokine-mediated signaling pathwayGO:00192219.1OAS3, OAS1, OAS2
9positive regulation of apoptotic processGO:00430659.0SCRIB, TLR3
10defense response to virusGO:00516078.5OAS3, OAS1, OAS2, TLR3

Molecular functions related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
12-5-oligoadenylate synthetase activityGO:00017309.1OAS3, OAS1, OAS2
2ATP bindingGO:00055249.1OAS2, OAS1, OAS3
3metal ion bindingGO:00468728.3OAS1, OAS3, CD209, OAS2
4double-stranded RNA bindingGO:00037258.2TLR3, OAS2, OAS1, OAS3

Products for genes affiliated with Tick-Borne Encephalitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Tick-Borne Encephalitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet