MCID: TCK003
MIFTS: 30

Tick-Borne Relapsing Fever malady

Infectious category

Summaries for Tick-Borne Relapsing Fever

Sources:
8Disease Ontology, 3CDC, 33MalaCards
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Disease Ontology:8 A relapsing fever that is characterized by relapsing or recurring episodes of fever, has material basis in borrelia hermsii, has material basis in borrelia parkeri or has material basis in borrelia duttoni, which are transmitted by soft ticks (ornithodoros parkeri and ornithodoros hermsii). the infection has symptom tachypnea, has symptom tachycardia, has symptom hepatosplenomegaly and has symptom lymphadenopathy.

MalaCards: Tick-Borne Relapsing Fever, also known as tick-borne relapsing fever nos, is related to q fever and severe acute respiratory syndrome, and has symptoms including lymphadenopathy, tachypnea and tachycardia. An important gene associated with Tick-Borne Relapsing Fever is FHL1 (four and a half LIM domains 1).

CDC:3 Relapsing fever is bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea. It is caused by certain species of Borrelia spirochetes. There are two types of relapsing fever:

Aliases & Classifications for Tick-Borne Relapsing Fever

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 27ICD9CM, 40NCIt, 57SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Aliases & Descriptions:

tick-borne relapsing fever 8 10 61
tick-borne relapsing fever nos 8
relapsing fever, tick-borne 8


External Ids:

Disease Ontology8 DOID:13036
ICD9CM27 087.1
SNOMED-CT57 10301003, 186821005
NCIt40 C34976
ICD1025 A68.1

Related Diseases for Tick-Borne Relapsing Fever

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Tick-Borne Relapsing Fever via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1q fever10.5
2severe acute respiratory syndrome10.3
3radiculopathy10.3
4glanders10.3
5colorado tick fever10.3
6tick infestation10.3
7headache10.3
8lyme disease10.0ELK3

Graphical network of diseases related to Tick-Borne Relapsing Fever:



Diseases related to tick-borne relapsing fever

Clinical Features for Tick-Borne Relapsing Fever

Sources:
8Disease Ontology
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Symptoms:

8 (see all 4)
  • lymphadenopathy
  • tachypnea
  • tachycardia
  • hepatosplenomegaly

Drugs & Therapeutics for Tick-Borne Relapsing Fever

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Tick-Borne Relapsing Fever

Drug clinical trials:

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Search CenterWatch for Tick-Borne Relapsing Fever

Genetic Tests for Tick-Borne Relapsing Fever

Anatomical Context for Tick-Borne Relapsing Fever

Animal Models for Tick-Borne Relapsing Fever or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Tick-Borne Relapsing Fever

Sources:
51PubMed
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Articles related to Tick-Borne Relapsing Fever:

(show top 50)    (show all 95)
idTitleAuthorsYear
1
Tick-borne relapsing fever in pregnancy. (23939208)
2013
2
Postexposure prophylaxis of tick-borne relapsing fever: lessons learned from recent outbreaks in Israel. (24107216)
2013
3
Elevated troponin and jarisch-herxheimer reaction in tick-borne relapsing Fever: a case report. (22567483)
2011
4
Molecular characterization of Borrelia persica, the agent of tick borne relapsing fever in Israel and the Palestinian Authority. (21124792)
2010
5
The epidemiology of tick-borne relapsing fever in Iran during 1997-2006. (19411042)
2009
6
Tick-borne relapsing fever in a new highland endemic focus of western Iran. (19695158)
2009
7
Congenital tick-borne relapsing fever: report of a case with transplacental transmission in the Islamic Republic of Iran. (19731794)
2009
8
Absence of transovarial transmission of Borrelia duttonii, a tick-borne relapsing fever agent, by the vector tick Ornithodoros moubata. (18454593)
2008
9
Incidence of tick-borne relapsing fever in west Africa: longitudinal study. (16815378)
2006
10
Doxycycline for the prevention of tick-borne relapsing fever. (17035657)
2006
11
Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida. (16081922)
2005
12
Tick-borne relapsing fever. (16342834)
2005
13
Tick-borne relapsing fever during pregnancy: a case report. (16363764)
2005
14
Tick-borne relapsing fever in North America. (11982310)
2002
15
The epidemiology of tick-borne relapsing fever in the United States. (12224586)
2002
16
Tick-borne relapsing fever caused by Borrelia turicatae. (12237608)
2002
17
Outbreak of tick-borne relapsing fever at the north rim of the Grand Canyon: evidence for effectiveness of preventive measures. (12135272)
2002
18
Tick-borne relapsing fever imported from West Africa: diagnosis by quantitative buffy coat analysis and in vitro culture of Borrelia crocidurae. (10325370)
1999
19
Tick-borne relapsing fever in the northwestern United States and southwestern Canada. (9455520)
1998
20
An interstate outbreak of tick-borne relapsing fever among vacationers at a Rocky Mountain cabin. (9660457)
1998
21
Tick-borne relapsing fever and pregnancy outcome in rural Tanzania. (9351408)
1997
22
A focus of tick-borne relapsing fever in southern Zaire. (9243047)
1997
23
Late relapse of tick-borne relapsing fever following treatment with doxycycline. (8434483)
1993
24
Mortality in high risk patients with tick-borne relapsing fever analysed by the Borrelia-index. (1800081)
1991
25
Tick-borne relapsing fever in intravenous drug abusers. (2926174)
1989
26
Tick-borne relapsing fever in a premature infant. (2415056)
1985
27
Tick borne relapsing fever in Tanzanian children. (6498926)
1984
28
Myocarditis in tick-borne relapsing fever. (6736677)
1984
29
Possible prevention of tick-borne relapsing fever in patients infected with Borrelia recurrentis. (6491372)
1984
30
Tick-borne relapsing fever in children. (7454488)
1980
31
Tick-borne relapsing fever in Colorado. Historical review and report of cases. (374757)
1979
32
Tick-borne relapsing fever in the Eastern United States. (623062)
1978
33
Tick-borne relapsing fever: an interstate outbreak originating at Grand Canyon National Park. (871120)
1977
34
Outbreak of tick-borne relapsing fever in Spokane County, Washington. (5394422)
1969
35
Tick-borne relapsing fever in the Judean hills, including a case with massive haematuria. (5707919)
1968
36
Tick-borne relapsing fever in Kashmir: mice inoculation--a diagnostic method of choice. (4964791)
1967
37
Tick-borne relapsing fever. The present position in Kenya. (5849187)
1965
38
The prevention and treatment of tick-borne relapsing fever with special reference to aureomycin and terramycin. (13281925)
1955
39
Tick-borne relapsing fever in Cyprus. (13010108)
1952
40
Tick-borne relapsing fever in Somaliland with special reference to the blood sedimentation rate. (14832869)
1951
41
The treatment of tick-borne relapsing fever in East Africa with special reference to aureomycin. (14887602)
1951
42
Treatment of tick-borne relapsing fever. Neoarsphenamine and other remedies. (14805134)
1951
43
Tick-borne relapsing fever on the Witwatersrand gold mines; its treatment with aureomycin. (15442582)
1950
44
Prevention of tick-borne relapsing fever. (15411885)
1950
45
Streptomycin in tick-borne relapsing fever of Kashmir. (15428046)
1950
46
Clinical manifestations of tick-borne relapsing fever with special reference to the disease in Cyprus. (18138841)
1949
47
A brief survey of 25 cases of tick-borne relapsing fever. (18151300)
1949
48
Discussion of methods for differentiating tick- from louse-borne relapsing fever spirochaetes. (18915552)
1948
49
Tick-borne relapsing fever: a case report. (20265460)
1947
50
On tick-borne relapsing fever]. (21000989)
1945

Genetic Variations for Tick-Borne Relapsing Fever

Expression for genes affiliated with Tick-Borne Relapsing Fever

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tick-Borne Relapsing Fever

Search GEO for disease gene expression data for Tick-Borne Relapsing Fever.

Pathways for genes affiliated with Tick-Borne Relapsing Fever

Compounds for genes affiliated with Tick-Borne Relapsing Fever

GO Terms for genes affiliated with Tick-Borne Relapsing Fever

Sources:
16Gene Ontology
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Cellular components related to Tick-Borne Relapsing Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1DNA replication factor A complexGO:0056629.5PURA, PURB

Biological processes related to Tick-Borne Relapsing Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of transcription, DNA-dependentGO:0458928.7ELK3, PURA, PURB

Molecular functions related to Tick-Borne Relapsing Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription factor bindingGO:0081349.5PURA, PURB
2SMAD bindingGO:0463329.4PURA, PURB
3single-stranded DNA bindingGO:0036979.2PURA, PURB
4purine-rich negative regulatory element bindingGO:0324229.1ELK3, PURA

Products for genes affiliated with Tick-Borne Relapsing Fever

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  • Proteins
  • Lysates
  • Antibodies

Sources for Tick-Borne Relapsing Fever

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet