MCID: TCK003
MIFTS: 32

Tick-Borne Relapsing Fever malady

Infectious diseases category

Summaries for Tick-Borne Relapsing Fever

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8Disease Ontology, 3CDC, 32MalaCards
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Disease Ontology:8 A relapsing fever that is characterized by relapsing or recurring episodes of fever, has material basis in borrelia hermsii, has material basis in borrelia parkeri or has material basis in borrelia duttoni, which are transmitted by soft ticks (ornithodoros parkeri and ornithodoros hermsii). the infection has symptom tachypnea, has symptom tachycardia, has symptom hepatosplenomegaly and has symptom lymphadenopathy.

MalaCards: Tick-Borne Relapsing Fever, also known as tick-borne relapsing fever nos, is related to relapsing fever and severe acute respiratory syndrome, and has symptoms including lymphadenopathy, tachypnea and tachycardia. An important gene associated with Tick-Borne Relapsing Fever is FHL1 (four and a half LIM domains 1).

CDC:3 Relapsing fever is bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea. It is caused by certain species of Borrelia spirochetes. There are two types of relapsing fever:

Aliases & Classifications for Tick-Borne Relapsing Fever

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8Disease Ontology, 10DISEASES, 60UMLS, 27ICD9CM, 39NCIt, 56SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

tick-borne relapsing fever 8 10 60
tick-borne relapsing fever nos 8
relapsing fever, tick-borne 8


External Ids:

Disease Ontology8 DOID:13036
ICD9CM27 087.1
SNOMED-CT56 10301003, 186821005
NCIt39 C34976
ICD1025 A68.1

Related Diseases for Tick-Borne Relapsing Fever

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17GeneCards, 18GeneDecks
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Diseases related to Tick-Borne Relapsing Fever via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1relapsing fever11.3
2severe acute respiratory syndrome10.3
3radiculopathy10.3
4glanders10.3
5colorado tick fever10.3
6malaria10.3
7myocarditis10.3
8tick infestation10.3
9lyme disease10.0ELK3

Graphical network of diseases related to Tick-Borne Relapsing Fever:



Diseases related to tick-borne relapsing fever

Clinical Features for Tick-Borne Relapsing Fever

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8Disease Ontology
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Symptoms:

8
  • lymphadenopathy
  • tachypnea
  • tachycardia
  • hepatosplenomegaly

Drugs & Therapeutics for Tick-Borne Relapsing Fever

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Tick-Borne Relapsing Fever

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Anatomical Context for Tick-Borne Relapsing Fever

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Animal Models for Tick-Borne Relapsing Fever or affiliated genes

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Publications for Tick-Borne Relapsing Fever

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50PubMed
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Articles related to Tick-Borne Relapsing Fever:

(show top 50)    (show all 94)
idTitleAuthorsYear
1
Postexposure prophylaxis of tick-borne relapsing fever: lessons learned from recent outbreaks in Israel. (24107216)
2013
2
Endemic foci of the tick-borne relapsing fever spirochete Borrelia crocidurae in Mali, West Africa, and the potential for human infection. (23209863)
2012
3
Tick-borne relapsing fever with cutaneous eschar and radiculopathy, Ethiopia. (22776391)
2012
4
A 20-year-old man with fever, headache, and neck stiffness. Neuroborreliosis with tick-borne relapsing fever. (21288847)
2011
5
Post exposure prophylaxis of tick-borne relapsing fever. (20012878)
2010
6
Molecular characterization of Borrelia persica, the agent of tick borne relapsing fever in Israel and the Palestinian Authority. (21124792)
2010
7
Tick-borne relapsing fever in a new highland endemic focus of western Iran. (19695158)
2009
8
Absence of transovarial transmission of Borrelia duttonii, a tick-borne relapsing fever agent, by the vector tick Ornithodoros moubata. (18454593)
2008
9
Tick-borne relapsing fever polymerase chain reaction of tick-borne relapsing fever caused by Borrelia hermsii. (17484230)
2007
10
Does tick-borne relapsing fever have an animal reservoir in East Africa? (18021022)
2007
11
Immunodominant epitope in the C-terminus of a variable major protein in Borrelia duttonii, an agent of tick-borne relapsing fever. (16625051)
2006
12
Postexposure treatment with doxycycline for the prevention of tick-borne relapsing fever. (16837678)
2006
13
Killed in action: microbiologists and clinicians as victims of their occupation. Part 4: Tick-borne Relapsing Fever, Malta Fever, Glanders, SARS. (16423683)
2006
14
Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida. (16081922)
2005
15
Absence of focal neurological involvement in tick-borne relapsing fever in northern Tanzania. (15885049)
2005
16
Tick-borne relapsing fever during pregnancy: a case report. (16363764)
2005
17
Tick-borne relapsing fever caused by Borrelia hermsii, Montana. (14519254)
2003
18
A newly identified tick-borne Borrelia species and relapsing fever in Tanzania. (14575974)
2003
19
Jarisch-Herxheimer reaction associated with ciprofloxacin administration for tick-borne relapsing fever. (12182387)
2002
20
The epidemiology of tick-borne relapsing fever in the United States. (12224586)
2002
21
Tick-borne relapsing fever caused by Borrelia turicatae. (12237608)
2002
22
Tick-borne relapsing fever imported from West Africa: diagnosis by quantitative buffy coat analysis and in vitro culture of Borrelia crocidurae. (10325370)
1999
23
Tick-borne relapsing fever in the northwestern United States and southwestern Canada. (9455520)
1998
24
Tick-borne relapsing fever in British Columbia, Canada: first isolation of Borrelia hermsii. (9817862)
1998
25
An interstate outbreak of tick-borne relapsing fever among vacationers at a Rocky Mountain cabin. (9660457)
1998
26
A focus of tick-borne relapsing fever in southern Zaire. (9243047)
1997
27
Late relapse of tick-borne relapsing fever following treatment with doxycycline. (8434483)
1993
28
Tick-borne relapsing fever in intravenous drug abusers. (2926174)
1989
29
Tick-borne relapsing fever due to Borrelia hermsii in British Columbia. (3940604)
1986
30
Tick borne relapsing fever in Tanzanian children. (6498926)
1984
31
Myocarditis in tick-borne relapsing fever. (6736677)
1984
32
Tick-borne relapsing fever in children. (7454488)
1980
33
Tick-borne relapsing fever in Colorado. Historical review and report of cases. (374757)
1979
34
Tick-borne relapsing fever: an interstate outbreak originating at Grand Canyon National Park. (871120)
1977
35
Outbreak of tick-borne relapsing fever in Spokane County, Washington. (5394422)
1969
36
Tick-borne relapsing fever in Kashmir: mice inoculation--a diagnostic method of choice. (4964791)
1967
37
A STUDY ON INDIAN TICK-BORNE RELAPSING FEVER. (14154432)
1964
38
Eradication of tick-borne relapsing fever in the Somaliland Protectorate by a tick destruction programme. (13324923)
1956
39
Tick-borne relapsing fever in Cyprus. (13010108)
1952
40
Tick-borne relapsing fever in Somaliland with special reference to the blood sedimentation rate. (14832869)
1951
41
The treatment of tick-borne relapsing fever in East Africa with special reference to aureomycin. (14887602)
1951
42
Prevention of tick-borne relapsing fever. (15411885)
1950
43
Streptomycin in tick-borne relapsing fever of Kashmir. (15428046)
1950
44
Tick-borne relapsing fever in Somaliland with special reference to the blood sedimentation rate. (15404743)
1950
45
Clinical manifestations of tick-borne relapsing fever with special reference to the disease in Cyprus. (18138841)
1949
46
Tick-borne relapsing fever in Kashmir. (18135918)
1949
47
A brief survey of 25 cases of tick-borne relapsing fever. (18151300)
1949
48
Tick-borne relapsing fever: a case report. (20265460)
1947
49
On tick-borne relapsing fever]. (21000989)
1945
50
Tick-borne Relapsing Fever. (20786348)
1945

Genetic Variations for Tick-Borne Relapsing Fever

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Expression for genes affiliated with Tick-Borne Relapsing Fever

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tick-Borne Relapsing Fever

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Pathways for genes affiliated with Tick-Borne Relapsing Fever

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Compounds for genes affiliated with Tick-Borne Relapsing Fever

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GO Terms for genes affiliated with Tick-Borne Relapsing Fever

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16Gene Ontology
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Cellular components related to Tick-Borne Relapsing Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1DNA replication factor A complexGO:0056629.5PURA, PURB

Biological processes related to Tick-Borne Relapsing Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of transcription, DNA-dependentGO:0458928.7ELK3, PURA, PURB

Molecular functions related to Tick-Borne Relapsing Fever according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription factor bindingGO:0081349.5PURA, PURB
2SMAD bindingGO:0463329.4PURA, PURB
3single-stranded DNA bindingGO:0036979.2PURA, PURB
4purine-rich negative regulatory element bindingGO:0324229.1ELK3, PURA

Products for genes affiliated with Tick-Borne Relapsing Fever

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  • Antibodies
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Sources for Tick-Borne Relapsing Fever

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet