MCID: TNC002
MIFTS: 40

Tinea Capitis malady

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Capitis

Aliases & Descriptions for Tinea Capitis:

Name: Tinea Capitis 12 14 69
Tinea Capitis Due to Trichophyton Rubrum 12
Dermatophytosis of Scalp or Beard 12
Trichophyton Rubrum Tinea Capitis 12
Dermatophytosis of Scalp 12
Scalp Ringworm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4337
ICD9CM 35 110.0
NCIt 47 C34536
UMLS 69 C0011640

Summaries for Tinea Capitis

Disease Ontology : 12 A dermatophytosis that results_in contagious fungal infection located in scalp, located in hair of head, located in eyebrow or located in eyelash, has material basis in Ascomycota fungi that belong to a group called dermatophytes and has symptom itching of the scalp, has symptom pus filled lesions on the scalp, and has symptom patches of hair loss, sometimes with a 'black dot' pattern.

MalaCards based summary : Tinea Capitis, also known as tinea capitis due to trichophyton rubrum, is related to kerion celsi and tinea favosa, and has symptoms including itching of the scalp, pus filled lesions on the scalp and patches of hair loss. An important gene associated with Tinea Capitis is KATNAL2 (Katanin Catalytic Subunit A1 Like 2). The drugs Griseofulvin and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include thyroid, skin and brain.

Wikipedia : 71 Tinea capitis (also known as \"herpes tonsurans\", \"ringworm of the hair\", \"ringworm of the scalp\",... more...

Related Diseases for Tinea Capitis

Graphical network of the top 20 diseases related to Tinea Capitis:



Diseases related to Tinea Capitis

Symptoms & Phenotypes for Tinea Capitis

Symptoms:

12
  • itching of the scalp
  • pus filled lesions on the scalp
  • patches of hair loss

Drugs & Therapeutics for Tinea Capitis

Drugs for Tinea Capitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Griseofulvin Approved, Vet_approved Phase 3 126-07-8 441140
2
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
3
Terbinafine Approved, Investigational, Vet_approved Phase 3 91161-71-6 5402 1549008
4
Fluconazole Approved Phase 3 86386-73-4 3365
5
Albendazole Approved, Vet_approved Phase 2, Phase 3 54965-21-8 2082
6 Antifungal Agents Phase 3,Phase 2,Phase 1
7 Anti-Infective Agents Phase 3,Phase 2
8 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
9 Cytochrome P-450 Enzyme Inhibitors Phase 3
10 Hormone Antagonists Phase 3
11 Hormones Phase 3
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
13 Steroid Synthesis Inhibitors Phase 3
14 Anthelmintics Phase 2, Phase 3
15 Antimitotic Agents Phase 2, Phase 3
16 Antiparasitic Agents Phase 2, Phase 3
17 Antiprotozoal Agents Phase 2, Phase 3
18 Micronutrients Phase 2, Phase 3
19 Trace Elements Phase 2, Phase 3
20 Papaya Nutraceutical Phase 2, Phase 3
21
Glucosamine Approved, Nutraceutical Phase 1 3416-24-8 439213
22 Ginkgo Nutraceutical Phase 1
23
Ciclopirox Approved, Investigational 29342-05-0 2749
24
Ketoconazole Approved, Investigational 65277-42-1 47576 3823
25
Selenium Approved, Vet_approved 7782-49-2
26 Antioxidants
27 Cytochrome P-450 CYP3A Inhibitors
28 Protective Agents

Interventional clinical trials:

(show all 11)
id Name Status NCT ID Phase
1 Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117767 Phase 3
2 Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117754 Phase 3
3 A Study Of Diflucan In Children With Ringworm Of The Scalp Completed NCT00645242 Phase 3
4 Design and Clinical Evaluation of a School Meal With Deworming Properties Completed NCT02725255 Phase 2, Phase 3
5 Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis Recruiting NCT02550496 Phase 3
6 Evaluation of Preclinical Toxicity andTherapeutic Efficacy of Kandhaga Rasayanam in Padarthamarai Completed NCT02238912 Phase 2
7 Safety and Efficacy of NAFT900 in Children With Tinea Capitis Withdrawn NCT02658292 Phase 2
8 Glucosamine Sulphate and Ginkgo Biloba as Antifungal Activity for Treating Tinea Pedis Recruiting NCT02882438 Phase 1
9 Selenium Sulfide, Ketoconazole and Ciclopirox Shampoo as Additional Treatments for Tinea Capitis (Scalp Ringworm) Completed NCT00127868
10 The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation Completed NCT00224926
11 Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation Completed NCT00590421

Search NIH Clinical Center for Tinea Capitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Tinea Capitis

Anatomical Context for Tinea Capitis

MalaCards organs/tissues related to Tinea Capitis:

39
Thyroid, Skin, Brain, Testes, B Cells, Pituitary

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Capitis:

18
Scalp, Hair Of Head, Eyebrow Or

Publications for Tinea Capitis

Articles related to Tinea Capitis:

(show top 50) (show all 566)
id Title Authors Year
1
Systemic antifungal therapy for tinea capitis in children: An abridged Cochrane Review. ( 27816294 )
2017
2
Ultraviolet dermoscopy for the diagnosis of tinea capitis. ( 28087021 )
2017
3
TERT promoter mutations: a genetic signature of benign and malignant thyroid tumours occurring in the context of tinea capitis irradiation. ( 27760791 )
2017
4
Trichophyton rubrum tinea capitis in an HIV-positive patient with generalized dermatophytosis. ( 28050591 )
2017
5
Tinea in Tots: Cases and Literature Review of Oral Antifungal Treatment of Tinea Capitis in Children under 2 Years of Age. ( 28088394 )
2017
6
Increased circulating Th17 cell in a patient with tinea capitis caused by Microsporum canis. ( 26666478 )
2016
7
Tinea capitis: Erregerspektrum und Epidemiologie im zeitlichen Wandel. ( 27509418 )
2016
8
Antifungal activity of Cleome gynandra L. aerial parts for topical treatment of Tinea capitis: an in vitro evaluation. ( 27391957 )
2016
9
Continuous increase of Trichophyton tonsurans as a cause of tinea capitis in the urban area of Paris, France: a 5-year-long study. ( 27744309 )
2016
10
Control of tinea capitis. ( 26707860 )
2016
11
Aspergillus niger - a possible new etiopathogenic agent in Tinea capitis? Presentation of two cases. ( 26963152 )
2016
12
Tinea capitis: a retrospective epidemiological comparative study. ( 27510759 )
2016
13
Dermoscopy as a useful supportive tool for the diagnosis of pityriasis amiantacea-like tinea capitis. ( 27648387 )
2016
14
Cathelicidin (LL-37) level in the scalp hair of patients with tinea capitis. ( 27915299 )
2016
15
Squamous cell carcinomas of the scalp induced by ionizing radiation for tinea capitis. ( 27595208 )
2016
16
Tinea capitis outbreak among paediatric refugee population, an evolving healthcare challenge. ( 27061446 )
2016
17
IL6-174 G>C Polymorphism (rs1800795) Association with Late Effects of Low Dose Radiation Exposure in the Portuguese Tinea Capitis Cohort. ( 27662210 )
2016
18
Trichoscopy as a useful method to differentiate tinea capitis from alopecia areata in children at Zagazig University Hospitals. ( 27654953 )
2016
19
Trichoscopy as an additional tool for the differential diagnosis of tinea capitis. ( 26799530 )
2016
20
Factors in Etiology and Predisposition of Adult Tinea Capitis and Review of Published Literature. ( 27004946 )
2016
21
Tinea capitis in adults. ( 27136624 )
2016
22
Tinea capitis in adults in southern Spain. A 17-year epidemiological study. ( 26774593 )
2016
23
Prevalence of Tinea Capitis among School Children in Nok Community of Kaduna State, Nigeria. ( 27471603 )
2016
24
Caries Experience among Adults Exposed to Low to Moderate Doses of Ionizing Radiation in Childhood - The Tinea Capitis Cohort. ( 26942172 )
2016
25
Identification of the causative dermatophyte of tinea capitis in children attending Mbarara Regional Referral Hospital in Uganda by PCR-ELISA and comparison with conventional mycological diagnostic methods. ( 27760831 )
2016
26
Systemic antifungal therapy for tinea capitis in children. ( 27169520 )
2016
27
Tinea Capitis: Current Status. ( 27599708 )
2016
28
The kerion: an angry tinea capitis. ( 27696388 )
2016
29
Mycological profile of tinea capitis in schoolchildren in rural southern Ethiopia. ( 27555558 )
2016
30
In vitro antifungal susceptibility profile of 12 antifungal drugs against 55 Trichophyton schoenleinii isolated from tinea capitis favosa in Iran, Turkey and China. ( 27956429 )
2016
31
Tinea capitis: temporal shift in pathogens and epidemiology. ( 27509419 )
2016
32
Epidemiological changes in tinea capitis over the sixty years of economic growth in China. ( 26260745 )
2015
33
Barriers to Treatment of Tinea Capitis in Children Living in the Jane Finch Community of Toronto. ( 26271966 )
2015
34
An unusual case of tinea capitis caused by Trichophyton schoenleinii in an elderly female. ( 25657920 )
2015
35
Tinea capitis in Campania, Italy: a 9-year retrospective study. ( 26224230 )
2015
36
An ultrastructural study on corkscrew hairs and cigarette-ash-shaped hairs observed by dermoscopy of tinea capitis. ( 26301780 )
2015
37
Prevalence of Tinea capitis in school going children from Mathare, informal settlement in Nairobi, Kenya. ( 26116079 )
2015
38
Long-Term Effects of Exposure to Ionizing Irradiation on Periodontal Health Status - The Tinea capitis Cohort Study. ( 26539423 )
2015
39
Administration of Oral Itraconazole Capsule with Whole Milk Shows Enhanced Efficacy As Supported by Scanning Electron Microscopy in a Child with Tinea Capitis Due to Microsporum canis. ( 26447934 )
2015
40
Black dot tinea capitis caused by trichophyton rubrum in an adult female presenting with cicatricial alopecia. ( 25751361 )
2015
41
Griseofulvin and Fluconazole Reduce Transmission of Tinea Capitis in Schoolchildren. ( 26215468 )
2015
42
A Double-Blind Randomized Placebo-Controlled Clinical Trial of Squalamine Ointment for tinea capitis Treatment. ( 25515244 )
2015
43
In vitro antifungal susceptibility of Trichophyton violaceum isolated from tinea capitis patients. ( 25492394 )
2015
44
Tinea capitis caused by Microsporum canis infection in a 75-year-old woman. ( 25876151 )
2015
45
Newly described features resulting from high-magnification dermoscopy of tinea capitis. ( 25471133 )
2015
46
Tinea Capitis: Mixed or Consecutive Infection with White and Violet Strains of Trichophyton violaceum: A Diagnostic or Therapeutic Challenge. ( 26814801 )
2015
47
Epidemiology of tinea capitis in northeast Iran: a retrospective analysis from 1998 to 2012. ( 26440755 )
2015
48
Bar code-like hair: dermoscopic marker of tinea capitis and tinea of the eyebrow. ( 25500038 )
2015
49
Tinea capitis caused by Trichophyton tonsurans presenting as an obscure patchy hair loss due to daily antifungal shampoo use. ( 26114071 )
2015
50
Dermatoscopic fi ndings as a complementary tool in the differential diagnosis of the etiological agent of tinea capitis. ( 26312662 )
2015

Variations for Tinea Capitis

Expression for Tinea Capitis

Search GEO for disease gene expression data for Tinea Capitis.

Pathways for Tinea Capitis

GO Terms for Tinea Capitis

Molecular functions related to Tinea Capitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.23 ARSI CTNNA3 DLGAP3 FLNC KATNAL2 PTCH1
2 actin filament binding GO:0051015 8.96 CTNNA3 FLNC

Sources for Tinea Capitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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