MCID: TNF001
MIFTS: 30

Tinea Favosa

Categories: Infectious diseases

Aliases & Classifications for Tinea Favosa

MalaCards integrated aliases for Tinea Favosa:

Name: Tinea Favosa 12 42 14 69
Favus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4336
ICD10 33 B35
MeSH 42 D014007
NCIt 47 C35072
SNOMED-CT 64 85375000
UMLS 69 C0040254

Summaries for Tinea Favosa

Disease Ontology : 12 A tinea capitis that results_in fungal infection located in scalp, located in glabrous skin or located in nail, has material basis in Ascomycota fungi that belong to a group called dermatophytes and results_in_formation_of scutula, yellowish cup-shaped crusts of dense masses of mycelium and epithelial debris, which develop at the surface of a hair follicle with the shaft in the center of the raised lesion. Removal of these crusts reveals an oozing, moist, red base. Later, atrophy of the skin occurs leaving a cicatricial alopecia and scarring.

MalaCards based summary : Tinea Favosa, also known as favus, is related to duodenal atresia and cardiomyopathy, dilated, 2b. An important gene associated with Tinea Favosa is RDH11 (Retinol Dehydrogenase 11 (All-Trans/9-Cis/11-Cis)), and among its related pathways/superpathways are Toll-Like receptor Signaling Pathways and Influenza A. The drugs Estradiol and Estradiol valerate have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Related Diseases for Tinea Favosa

Diseases related to Tinea Favosa via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
id Related Disease Score Top Affiliating Genes
1 duodenal atresia 10.3 CHD7 FOXE1
2 cardiomyopathy, dilated, 2b 10.2 CHD7 FOXE1
3 axillary adenitis 10.2 IL1B NLRP3
4 walker dyson syndrome 10.2 IL1B NLRP3
5 milk allergy 10.1 IL1B NLRP3
6 senile reticular retinal degeneration 10.1 IL1B NLRP3
7 yao syndrome 10.1 IL1B NLRP3
8 whistling face syndrome, recessive form 10.1 IL1B NLRP3
9 noma 10.1 IL1B NLRP3
10 gliosarcoma 10.0 CASP1 IL1B
11 sinusitis 10.0 IL1B NLRP3
12 tinea capitis 10.0
13 asbestosis 10.0 IL1B NLRP3
14 rift valley fever 10.0 CASP1 IL1B
15 isolated growth hormone deficiency 9.9 CASP1 IL1B
16 dermatophytosis 9.8
17 pleomorphic lipoma 9.8 CASP1 IL1B
18 histoplasmosis retinitis 9.8 CTSB IL1B
19 congenital nystagmus 9.8 IL1B NLRP3
20 kaposi sarcoma 9.8 IL1B NLRP3
21 keratomalacia 9.8 CASP1 IL1B
22 lingual goiter 9.7 IL1B NLRP3
23 alopecia 9.7
24 tinea cruris 9.7
25 coccidioidomycosis 9.7
26 histoplasmosis 9.7
27 lichen planus 9.7
28 mycetoma 9.7
29 familial cold-induced inflammatory syndrome 1 9.6 CASP1 IL1B NLRP3
30 dystonia 17, torsion, autosomal recessive 9.6 CASP1 IL1B NLRP3
31 cinca syndrome 9.6 CASP1 IL1B NLRP3
32 muckle-wells syndrome 9.5 CASP1 IL1B NLRP3
33 familial mediterranean fever, ad 9.5 CASP1 IL1B NLRP3
34 giant axonal neuropathy 2 9.5 CASP1 IL1B NLRP3
35 pulmonary embolism 9.5 IL1B NLRP3
36 ciliary body cancer 7.5 CASP1 CHD7 CTSB FOXE1 IL1B NLRP3

Graphical network of the top 20 diseases related to Tinea Favosa:



Diseases related to Tinea Favosa

Symptoms & Phenotypes for Tinea Favosa

MGI Mouse Phenotypes related to Tinea Favosa:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.55 CASP1 CHD7 CTSB FOXE1 NLRP3
2 homeostasis/metabolism MP:0005376 9.43 CASP1 CHD7 CTSB FOXE1 IL1B NLRP3
3 integument MP:0010771 9.02 CASP1 CTSB FOXE1 IL1B NLRP3

Drugs & Therapeutics for Tinea Favosa

Drugs for Tinea Favosa (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
2 Estradiol valerate Phase 2 979-32-8
3 Contraceptive Agents Phase 2
4 Hormone Antagonists Phase 2
5 Hormones Phase 2
6 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
7 Estradiol 17 beta-cypionate Phase 2
8 Estradiol 3-benzoate Phase 2
9 Estrogens Phase 2
10 Polyestradiol phosphate Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass Unknown status NCT01928082 Phase 2 Transdermal estradiol

Search NIH Clinical Center for Tinea Favosa

Cochrane evidence based reviews: tinea favosa

Genetic Tests for Tinea Favosa

Anatomical Context for Tinea Favosa

MalaCards organs/tissues related to Tinea Favosa:

39
Skin, Bone

Publications for Tinea Favosa

Articles related to Tinea Favosa:

id Title Authors Year
1
Generalized Favus: The Story of a Legendary Case of Tinea Favosa. ( 25583289 )
2015
2
Goya and tinea favosa. ( 25387510 )
2014
3
Study of 73 cases of tinea capitis and tinea favosa in adults and adolescents. ( 5697378 )
1968
4
DEHYDROEMETINE IN FUNGUS INFECTION (TINEA FAVOSA). ( 14201655 )
1964
5
Treatment Op Tinea Favosa. ( 21379048 )
1843

Variations for Tinea Favosa

Expression for Tinea Favosa

Search GEO for disease gene expression data for Tinea Favosa.

Pathways for Tinea Favosa

GO Terms for Tinea Favosa

Cellular components related to Tinea Favosa according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 NLRP3 inflammasome complex GO:0072559 8.62 CASP1 NLRP3

Biological processes related to Tinea Favosa according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 palate development GO:0060021 9.46 CHD7 FOXE1
2 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.43 CASP1 NLRP3
3 cellular response to mechanical stimulus GO:0071260 9.4 CASP1 IL1B
4 regulation of inflammatory response GO:0050727 9.37 CASP1 NLRP3
5 cellular response to organic substance GO:0071310 9.26 CASP1 IL1B
6 positive regulation of interleukin-1 beta secretion GO:0050718 9.16 CASP1 NLRP3
7 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 9.02 NLRP3
8 response to ATP GO:0033198 8.96 CASP1 IL1B
9 interleukin-1 beta production GO:0032611 8.8 CASP1 IL1B NLRP3

Molecular functions related to Tinea Favosa according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cysteine-type endopeptidase activity GO:0004197 8.62 CASP1 CTSB

Sources for Tinea Favosa

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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