MCID: TNF001
MIFTS: 34

Tinea Favosa

Categories: Infectious diseases

Aliases & Classifications for Tinea Favosa

MalaCards integrated aliases for Tinea Favosa:

Name: Tinea Favosa 12 41 14 69
Favus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4336
ICD10 32 B35
MeSH 41 D014007
NCIt 46 C35072
SNOMED-CT 64 85375000
UMLS 69 C0040254

Summaries for Tinea Favosa

Disease Ontology : 12 A tinea capitis that results_in fungal infection located in scalp, located in glabrous skin or located in nail, has material basis in Ascomycota fungi that belong to a group called dermatophytes and results_in_formation_of scutula, yellowish cup-shaped crusts of dense masses of mycelium and epithelial debris, which develop at the surface of a hair follicle with the shaft in the center of the raised lesion. Removal of these crusts reveals an oozing, moist, red base. Later, atrophy of the skin occurs leaving a cicatricial alopecia and scarring.

MalaCards based summary : Tinea Favosa, also known as favus, is related to choanal atresia, posterior and charge syndrome. An important gene associated with Tinea Favosa is RDH11 (Retinol Dehydrogenase 11 (All-Trans/9-Cis/11-Cis)), and among its related pathways/superpathways are Toll-Like receptor Signaling Pathways and Influenza A. The drugs Estradiol and Estradiol valerate have been mentioned in the context of this disorder. Affiliated tissues include scalp, glabrous skin or and skin, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Related Diseases for Tinea Favosa

Graphical network of the top 20 diseases related to Tinea Favosa:



Diseases related to Tinea Favosa

Symptoms & Phenotypes for Tinea Favosa

MGI Mouse Phenotypes related to Tinea Favosa:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.55 CASP1 CHD7 CTSB FOXE1 NLRP3
2 homeostasis/metabolism MP:0005376 9.43 CASP1 CHD7 CTSB FOXE1 IL1B NLRP3
3 integument MP:0010771 9.02 CASP1 CTSB FOXE1 IL1B NLRP3

Drugs & Therapeutics for Tinea Favosa

Drugs for Tinea Favosa (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
2 Estradiol valerate Phase 2 979-32-8
3 Contraceptive Agents Phase 2
4 Hormone Antagonists Phase 2
5 Hormones Phase 2
6 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
7 Estradiol 17 beta-cypionate Phase 2
8 Estradiol 3-benzoate Phase 2
9 Estrogens Phase 2
10 Polyestradiol phosphate Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass Unknown status NCT01928082 Phase 2 Transdermal estradiol

Search NIH Clinical Center for Tinea Favosa

Cochrane evidence based reviews: tinea favosa

Genetic Tests for Tinea Favosa

Anatomical Context for Tinea Favosa

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Favosa:

18
Scalp, Glabrous Skin Or

MalaCards organs/tissues related to Tinea Favosa:

38
Skin, Bone

Publications for Tinea Favosa

Articles related to Tinea Favosa:

# Title Authors Year
1
Generalized Favus: The Story of a Legendary Case of Tinea Favosa. ( 25583289 )
2015
2
Goya and tinea favosa. ( 25387510 )
2014
3
Study of 73 cases of tinea capitis and tinea favosa in adults and adolescents. ( 5697378 )
1968
4
DEHYDROEMETINE IN FUNGUS INFECTION (TINEA FAVOSA). ( 14201655 )
1964
5
Treatment Op Tinea Favosa. ( 21379048 )
1843

Variations for Tinea Favosa

Expression for Tinea Favosa

Search GEO for disease gene expression data for Tinea Favosa.

Pathways for Tinea Favosa

GO Terms for Tinea Favosa

Cellular components related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NLRP3 inflammasome complex GO:0072559 8.62 CASP1 NLRP3

Biological processes related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 palate development GO:0060021 9.46 CHD7 FOXE1
2 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.43 CASP1 NLRP3
3 cellular response to mechanical stimulus GO:0071260 9.4 CASP1 IL1B
4 regulation of inflammatory response GO:0050727 9.37 CASP1 NLRP3
5 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 9.32 CASP1 NLRP3
6 cellular response to organic substance GO:0071310 9.26 CASP1 IL1B
7 positive regulation of interleukin-1 beta secretion GO:0050718 9.16 CASP1 NLRP3
8 response to ATP GO:0033198 8.96 CASP1 IL1B
9 interleukin-1 beta production GO:0032611 8.8 CASP1 IL1B NLRP3

Molecular functions related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cysteine-type endopeptidase activity GO:0004197 8.62 CASP1 CTSB

Sources for Tinea Favosa

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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