MCID: TTH006
MIFTS: 52

Tooth Disease malady

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Tooth Disease

Aliases & Descriptions for Tooth Disease:

Name: Tooth Disease 12 14
Dental Disorder 12 52
Tooth Diseases 42 69
Tooth Disorders 41
Dental Diseases 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1091
MeSH 42 D014076
ICD10 33 K02.9
UMLS 69 C0040435

Summaries for Tooth Disease

MedlinePlus : 41 your teeth are made of a hard, bonelike material. inside the tooth are nerves and blood vessels. you need your teeth for many activities you may take for granted. these include eating, speaking and even smiling. but tooth disorders are nothing to smile about. they include problems such as cavities (also known as tooth decay), infections, and injuries. the most familiar symptom of a tooth problem is a toothache. others include worn-down or loose teeth. it's important that you see a dentist if you have any problems with your teeth. fortunately, you can prevent many tooth disorders by taking care of your teeth and keeping them clean.

MalaCards based summary : Tooth Disease, also known as dental disorder, is related to charcot-marie-tooth disease, type 1e and charcot-marie-tooth disease, type 2a1, and has symptoms including halitosis, snoring and toothache. An important gene associated with Tooth Disease is GJB1 (Gap Junction Protein Beta 1), and among its related pathways/superpathways is Neural Crest Differentiation. The drugs Acetylcholine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and bone, and related phenotypes are behavior/neurological and cellular

Related Diseases for Tooth Disease

Diseases related to Tooth Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 270)
id Related Disease Score Top Affiliating Genes
1 charcot-marie-tooth disease, type 1e 33.7 EGR2 GJB1 KIF1B MPZ PMP22
2 charcot-marie-tooth disease, type 2a1 33.7 KIF1B MFN2
3 charcot-marie-tooth disease, type 2i 33.7 KIF1B MPZ
4 charcot-marie-tooth disease, dominant intermediate d 33.6 KIF1B MPZ
5 charcot-marie-tooth disease, axonal, type 2k 33.6 GDAP1 MTMR2
6 dejerine-sottas disease 32.9 GDAP1 GJB1 KIF1B MFN2 MPZ PMP22
7 hereditary motor and sensory neuropathy via 32.7 MFN2 PMP22
8 charcot-marie-tooth disease, type 2j 32.7 EGR2 FGD4 FIG4 GARS GDAP1 GJB1
9 neuropathy, congenital hypomyelinating 32.3 EGR2 FGD4 GDAP1 GJB1 KIF1B LITAF
10 charcot-marie-tooth disease 12.3
11 charcot-marie-tooth disease, type 2e 12.3
12 charcot-marie-tooth disease, type 1a 12.3
13 charcot-marie-tooth disease, type 1b 12.3
14 charcot-marie-tooth disease, type 4a 12.2
15 charcot-marie-tooth disease, type 4h 12.2
16 charcot-marie-tooth disease, type 4b2 12.2
17 charcot-marie-tooth disease, type 2b 12.2
18 charcot-marie-tooth disease, type 4c 12.2
19 charcot-marie-tooth disease, type 2d 12.2
20 charcot-marie-tooth disease, type 4b1 12.2
21 charcot-marie-tooth disease, type 2a2 12.2
22 charcot-marie-tooth disease, type 4j 12.2
23 charcot-marie-tooth disease, type 1c 12.2
24 charcot-marie-tooth disease, type 4f 12.2
25 charcot-marie-tooth disease, type 1d 12.2
26 charcot-marie-tooth disease, type 4b3 12.2
27 charcot-marie-tooth disease, type 2b1 12.2
28 charcot-marie-tooth disease, type 2b2 12.1
29 charcot-marie-tooth disease, dominant intermediate b 12.1
30 charcot-marie-toothe disease, axonal, type 2p 12.1
31 charcot-marie-tooth disease, axonal, type 2s 12.1
32 charcot-marie-tooth disease, type 4d 12.1
33 charcot-marie-tooth disease, axonal, type 2l 12.1
34 charcot-marie-tooth disease, type 2r 12.1
35 charcot-marie-tooth disease, dominant intermediate e 12.1
36 charcot-marie-tooth disease, recessive intermediate, a 12.1
37 charcot-marie-tooth disease, type 1f 12.1
38 charcot-marie-tooth disease, axonal, type 2q 12.1
39 charcot-marie-tooth disease, axonal, type 2u 12.1
40 charcot-marie-tooth disease type 4k 12.1
41 charcot-marie-tooth disease, axonal, type 20 12.1
42 charcot-marie-tooth disease, axonal, type 2n 12.1
43 charcot-marie-tooth disease, x-linked recessive, 5 12.1
44 charcot-marie-tooth disease, axonal, type 2f 12.1
45 charcot-marie-tooth disease, recessive intermediate, b 12.1
46 charcot-marie-tooth disease, axonal, type 2v 12.1
47 charcot-marie-tooth disease, dominant intermediate c 12.1
48 charcot-marie-tooth disease, axonal, type 2h 12.1
49 charcot-marie-tooth disease, recessive intermediate d 12.1
50 charcot-marie-tooth disease, x-linked dominant, 6 12.1

Graphical network of the top 20 diseases related to Tooth Disease:



Diseases related to Tooth Disease

Symptoms & Phenotypes for Tooth Disease

UMLS symptoms related to Tooth Disease:


halitosis, snoring, toothache, poor dentition, orofacial pain

MGI Mouse Phenotypes related to Tooth Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.27 LMNA LRSAM1 MED25 MFN2 MPZ MTMR2
2 cellular MP:0005384 10.02 MPZ PMP22 SBF1 EGR2 GDAP1 GJB1
3 mortality/aging MP:0010768 10 KIF1B LMNA MED25 MFN2 MPZ MTMR2
4 limbs/digits/tail MP:0005371 9.8 EGR2 FIG4 GDAP1 LMNA MED25 MTMR2
5 nervous system MP:0003631 9.53 EGR2 FGD4 FIG4 GARS GDAP1 GJB1
6 muscle MP:0005369 9.5 LMNA MFN2 PMP22 SH3TC2 FIG4 GARS

Drugs & Therapeutics for Tooth Disease

Drugs for Tooth Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 961)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 4,Phase 2,Phase 1 51-84-3 187
2
Benzocaine Approved Phase 4,Phase 3,Phase 1,Phase 2 1994-09-7, 94-09-7 2337
3
Ephedrine Approved Phase 4 299-42-3 9294
4
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 137-58-6 3676
5
Oxymetazoline Approved Phase 4,Phase 1 1491-59-4 4636
6
Phenylephrine Approved Phase 4,Phase 1 59-42-7 6041
7
Pseudoephedrine Approved Phase 4 90-82-4 7028
8
Tetracaine Approved, Vet_approved Phase 4 94-24-6 5411
9
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
10 sodium fluoride Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7681-49-4
11
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-43-4 5816
12
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 55-56-1 9552079 2713
13
Hexetidine Approved Phase 4 141-94-6
14
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
15
Silver sulfadiazine Approved, Vet_approved Phase 4 22199-08-2 441244
16
Lopinavir Approved Phase 4,Phase 3,Phase 2 192725-17-0 92727
17
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 2 155213-67-5 392622
18
Lamivudine Approved, Investigational Phase 4,Phase 3 134678-17-4 60825
19
Nevirapine Approved Phase 4 129618-40-2 4463
20
Zidovudine Approved Phase 4,Phase 3 30516-87-1 35370
21
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 26787-78-0 33613 2171
22
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
23
Sorbitol Approved Phase 4,Phase 2,Phase 3 50-70-4 5780
24
Salicylic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 69-72-7 338
25
Ibuprofen Approved Phase 4,Phase 3,Phase 2 15687-27-1 3672
26
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
27
Methamphetamine Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1 537-46-2 10836
28
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3 59467-70-8 4192
29
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
30
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
31
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2216-51-5 16666
32
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2 2180-92-9, 38396-39-3 2474
33
Zinc Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 7440-66-6 32051 23994
34
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 443-48-1 4173
35
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
36
Efavirenz Approved, Investigational Phase 4,Phase 2 154598-52-4 64139
37
Emtricitabine Approved, Investigational Phase 4,Phase 2 143491-57-0 60877
38
Tenofovir Approved, Investigational Phase 4,Phase 2 147127-20-6 464205
39
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2 216974-75-3
40
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
41
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 85721-33-1 2764
42
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
43
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
44
Codeine Approved, Illicit Phase 4,Phase 3 76-57-3 5284371
45
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2 15307-86-5 3033
46
Guaifenesin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
47
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 161796-78-7, 119141-88-7 4594 9579578
48
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 22204-53-1 1302 156391
49
Piroxicam Approved, Investigational Phase 4,Phase 3 36322-90-4 5280452 54676228
50
Glycerol Approved, Experimental Phase 4 56-81-5 753

Interventional clinical trials:

(show top 50) (show all 2494)
id Name Status NCT ID Phase
1 Success Rate Evaluation of Miniature Pulpotomy With MTA in Primary Molars Unknown status NCT02286648 Phase 4
2 Study of the Safety and Efficacy of Botox in Bruxism Unknown status NCT00908050 Phase 4
3 Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel Unknown status NCT01142440 Phase 4
4 Clinical Comparison of RPDs Retained by Conical and Galvanoformed Double Crowns. Unknown status NCT00176215 Phase 4
5 Elmex Gel Efficacy in Preventing White Spot Lesions Unknown status NCT00268138 Phase 4
6 Manually Versus Digitally Fabricated Removable Partial Dentures Unknown status NCT01191073 Phase 4
7 Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins Unknown status NCT02449707 Phase 4
8 Effects of Botulinum Toxin Type A(Meditoxin®) on Sleep Bruxism Unknown status NCT01336439 Phase 4
9 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
10 Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel Unknown status NCT00846690 Phase 4
11 Periodontal Therapy in Coronary Artery Patients Unknown status NCT01609725 Phase 4
12 Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care Unknown status NCT01195493 Phase 4
13 Evaluation of Photodynamic Treatment FOTOSAN® Efficacy in Periodontology Unknown status NCT02030470 Phase 4
14 Bone Quality and Quantity Following Guided Bone Regeneration Prior to Dental Implant Placement Unknown status NCT01603693 Phase 4
15 Clinical, Microbiological and Biochemical Effects of the Antimicrobial Photodynamic Therapy Unknown status NCT01532674 Phase 4
16 Methodology Antiseptic Application, Influence on Oral Biofilm. Unknown status NCT02267239 Phase 4
17 Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite") Unknown status NCT01933386 Phase 4
18 Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects Unknown status NCT01440426 Phase 4
19 PREVENT-HF: Prevention of Heart Failure Events With Impedance Cardiography Testing Unknown status NCT00409916 Phase 4
20 RAltegravir Switch STudy: Effects on Endothelial Recovery Unknown status NCT01453933 Phase 4
21 Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity. Unknown status NCT00156741 Phase 4
22 MEDICLAS Study (Metabolic Effects of Different Classes of AntiretroviralS) Unknown status NCT00122226 Phase 4
23 Ketamine on Acute Pain in Females and Males Completed NCT00232492 Phase 4
24 Efficacy of a Whitening Dentifrice on Tooth Discoloration Completed NCT02741427 Phase 4
25 Clinical Effectiveness of In-office Bleaching Activated With a LED/Laser Device Completed NCT01231243 Phase 4
26 Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners Completed NCT01962012 Phase 4
27 An Efficacy Study of Stain Control of a 67% Sodium Bicarbonate Containing Toothpaste on Chlorhexidine Tooth Staining Completed NCT01962493 Phase 4
28 Effectiveness of Diclofenac and Its Association to Codeine After Lower Third Molar Extraction. Completed NCT02547896 Phase 4
29 Lower Third Molar Removal With 2% and 4% Articaine Completed NCT02457325 Phase 4
30 Comparison of the Clinical Efficacy of Naproxen, Associated or Not With Esomeprazol, in Lower Third Molar Removal Completed NCT02494856 Phase 4
31 Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery Completed NCT02450487 Phase 4
32 Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients Completed NCT02017873 Phase 4
33 AUGMENTIN™ in Dental Infections Completed NCT02141217 Phase 4
34 Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier Completed NCT00638677 Phase 4
35 Clinical Study of the Whitening Dentifrices on Tooth Color and Sensitivity Completed NCT02483013 Phase 4
36 Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars Completed NCT01496846 Phase 4
37 Impact of Fluoride Vanish Application in Dental Prevention for Elderly Completed NCT01038817 Phase 4
38 An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity Completed NCT02476032 Phase 4
39 Use of Fissure Sealants on Primary Molars Completed NCT01438866 Phase 4
40 Anesthetic Efficacy of Articaine and Lidocaine in Lower Molars With Irreversible Pulpits Completed NCT01912755 Phase 4
41 Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients Completed NCT01329731 Phase 4
42 The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions Completed NCT02953886 Phase 4
43 Nano-hydroxyapatite With Potassium Nitrate in the Therapy of the Dental Sensitivity Completed NCT02895321 Phase 4
44 Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity Completed NCT02773758 Phase 4
45 Comparison of the Effect of Fluoride Remineralizer Gel and Foam Completed NCT02490592 Phase 4
46 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study Completed NCT02424097 Phase 4
47 Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients Completed NCT01768390 Phase 4
48 Dexketoprofen Trometamol in Postoperative Endodontic Pain Completed NCT02086097 Phase 4
49 Preventive and Therapeutic Proximal Sealants Completed NCT02338180 Phase 4
50 Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study Completed NCT00723515 Phase 4

Search NIH Clinical Center for Tooth Disease

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: tooth diseases

Genetic Tests for Tooth Disease

Anatomical Context for Tooth Disease

MalaCards organs/tissues related to Tooth Disease:

39
Testes, Brain, Bone, Skin, Skeletal Muscle, Spinal Cord

Publications for Tooth Disease

Articles related to Tooth Disease:

(show top 50) (show all 981)
id Title Authors Year
1
Rapid Identification of Pathogenic Variants in Two Cases of Charcot-Marie-Tooth Disease by Gene-Panel Sequencing. ( 28379183 )
2017
2
Gait patterns of children and adolescents with Charcot-Marie-Tooth disease. ( 28527386 )
2017
3
Unilateral oculomotor palsy in Charcot-Marie-Tooth disease 1A (CMT 1A). ( 28214652 )
2017
4
Charcot-Marie-Tooth disease: genetic subtypes in the Sardinian population. ( 28286897 )
2017
5
Confirmation of the GNB4 gene as causal for Charcot-Marie-Tooth disease by a novel de novo mutation in a Czech patient. ( 27908631 )
2017
6
Intermediate Charcot-Marie-Tooth disease: an electrophysiological reappraisal and systematic review. ( 28364294 )
2017
7
LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P. ( 28335037 )
2017
8
Erratum: Plasma neurofilament heavy chain is not a useful biomarker in Charcot-Marie-Tooth disease. ( 27995668 )
2017
9
Whole-Exome Sequencing Identifies a Novel Homozygous Frameshift Mutation in the MTMR2 Gene as a Causative Mutation in a Patient with Charcot-Marie-Tooth Disease Type 4B1. ( 28509084 )
2017
10
Targeted exomes reveal simultaneous MFN2 and GDAP1 mutations in a severe Charcot-Marie-Tooth disease type 2 phenotype. ( 28211244 )
2017
11
Phenotypical features of a new dominant GDAP1 pathogenic variant (p.R226del) in axonal Charcot-Marie-Tooth disease. ( 28236508 )
2017
12
Similar clinical, pathological, and genetic features in Chinese patients with autosomal recessive and dominant Charcot-Marie-Tooth disease type 2K. ( 28495047 )
2017
13
Anatomical distributional defects in mutant genes associated with dominant intermediate Charcot-Marie-Tooth disease type C in an adenovirus-mediated mouse model. ( 28469666 )
2017
14
Long-Term Effective Thalamic Deep Brain Stimulation for Neuropathic Tremor in Two Patients with Charcot-Marie-Tooth Disease. ( 28297702 )
2017
15
Clinical and mutational spectrum of Japanese patients with Charcot-Marie-Tooth disease caused by GDAP1 variants. ( 28244113 )
2017
16
New mutation in a patient with Charcot-Marie-Tooth disease. ( 28318735 )
2017
17
Genetic and clinical characteristics of NEFL-related Charcot-Marie-Tooth disease. ( 28501821 )
2017
18
Severe vincristine-induced polyneuropathy in a teenager with anaplastic medulloblastoma and undiagnosed Charcot-Marie-Tooth disease. ( 28438772 )
2017
19
Mitochondrial trifunctional protein deficiency: an adult patient with similar progress to Charcot-Marie-Tooth disease. ( 28132977 )
2017
20
Deterioration in gait and functional ambulation in children and adolescents with Charcot-Marie-Tooth disease over 12 months. ( 28495045 )
2017
21
Clinical characterization and genetic analysis of Korean patients with X-linked Charcot-Marie-Tooth disease type 1. ( 28448691 )
2017
22
Erratum to: Charcot-Marie-Tooth disease: genetic subtypes in the Sardinian population. ( 28389936 )
2017
23
Rigid spine syndrome associated with sensory-motor axonal neuropathy resembling Charcot-Marie-Tooth disease is characteristic of Bcl-2-associated athanogene-3 gene mutations even without cardiac involvement. ( 28224639 )
2017
24
A Novel Asp121Asn Mutation of Myelin Protein Zero Is Associated with Late-Onset Axonal Charcot-Marie-Tooth Disease, Hearing Loss and Pupil Abnormalities. ( 27774063 )
2016
25
Severe axonal Charcot-Marie-Tooth disease with proximal weakness caused by de novo mutation in the MORC2 gene. ( 26912637 )
2016
26
Reasons Charcot-Marie-Tooth disease due to mutations in the MME gene should not be named AR-CMT2T. ( 27458975 )
2016
27
Successful Treatment of Amyloid Light-chain Amyloidosis in a Charcot-Marie-Tooth Disease Patient with Lenalidomide, Cyclophosphamide, and Dexamethasone. ( 27629972 )
2016
28
X-linked Charcot-Marie-Tooth disease type 6 (CMTX6) patients with a p.R158H mutation in the pyruvate dehydrogenase kinase isoenzyme 3 gene. ( 26801680 )
2016
29
Precision Medicine for Charcot-Marie-Tooth Disease. ( 27042938 )
2016
30
Exclusive expression of the Rab11 effector SH3TC2 in Schwann cells links integrin-I+6 and myelin maintenance to Charcot-Marie-Tooth disease type 4C. ( 27068304 )
2016
31
Phenotypic Variability of Childhood Charcot-Marie-Tooth Disease. ( 27043305 )
2016
32
The Role of Rehabilitation in the Management of Patients with Charcot-Marie-Tooth Disease: Report of Two Cases. ( 27703571 )
2016
33
De novo PMP2 mutations in families with type 1 Charcot-Marie-Tooth disease. ( 27009151 )
2016
34
Effective cauda equina decompression in two siblings with Charcot-Marie-Tooth disease type 1B. ( 27614573 )
2016
35
Narcolepsy with cataplexy in a child with Charcot-Marie-Tooth disease. Case Report. ( 27857041 )
2016
36
MFN2 transcripts escaping from nonsense-mediated mRNA decay pathway cause Charcot-Marie-Tooth disease type 2A2. ( 27154191 )
2016
37
[Analysis of heterozygous duplication of PMP22 gene in a pedigree affected with Charcot Marie Tooth disease]. ( 27577214 )
2016
38
Sport activity in Charcot-Marie-Tooth disease: A case study of a Paralympic swimmer. ( 27460291 )
2016
39
Progression of motor axon dysfunction and ectopic Nav1.8 expression in a mouse model of Charcot-Marie-Tooth disease 1B. ( 27215377 )
2016
40
IGHMBP2-related clinical and genetic features in a cohort of Chinese Charcot-Marie-Tooth disease type 2 patients. ( 28065684 )
2016
41
Handwriting difficulties of children with Charcot-Marie-Tooth disease type 1A. ( 27917570 )
2016
42
Anesthetic Management of a Patient With Charcot-Marie-Tooth Disease. ( 27269665 )
2016
43
Whole-body MR neurography: Prospective feasibility study in polyneuropathy and Charcot-Marie-Tooth disease. ( 27126998 )
2016
44
A New Next-Generation Sequencing-Based Assay for Concurrent Preimplantation Genetic Diagnosis of Charcot-Marie-Tooth Disease Type 1A and Aneuploidy Screening. ( 27020035 )
2016
45
Clinico-genetics in Korean Charcot-Marie-Tooth disease type 2Z with MORC2 mutations. ( 27105897 )
2016
46
Charcot-Marie-Tooth disease type 2G redefined by a novel mutation in LRSAM1. ( 27686364 )
2016
47
Clinical and genetic spectra of Charcot-Marie-Tooth disease in Chinese Han patients. ( 27862672 )
2016
48
Novel outcome measures for Charcot-Marie-Tooth disease: validation and reliability of the 6-min walk test and StepWatch(a8c) Activity Monitor and identification of the walking features related to higher quality of life. ( 27160471 )
2016
49
Mutation Analysis of Gap Junction Protein Beta 1 and Genotype-Phenotype Correlation in X-linked Charcot-Marie-Tooth Disease in Chinese Patients. ( 27098783 )
2016
50
Aberrant trafficking of a Leu89Pro connexin32 mutant associated with X-linked dominant Charcot-Marie-Tooth disease. ( 27367520 )
2016

Variations for Tooth Disease

Expression for Tooth Disease

Search GEO for disease gene expression data for Tooth Disease.

Pathways for Tooth Disease

Pathways related to Tooth Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.81 GJB1 MPZ PMP22

GO Terms for Tooth Disease

Cellular components related to Tooth Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.73 FGD4 GARS GDAP1 HSPB1 LITAF LMNA
2 axon cytoplasm GO:1904115 8.8 HSPB1 KIF1B NEFL

Biological processes related to Tooth Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peripheral nervous system development GO:0007422 9.43 EGR2 PMP22
2 phosphatidylinositol biosynthetic process GO:0006661 9.43 FIG4 MTMR2 SBF1
3 phosphatidylinositol metabolic process GO:0046488 9.4 FIG4 MTMR2
4 mitochondrial fusion GO:0008053 9.37 GDAP1 MFN2
5 negative regulation of endocytosis GO:0045806 9.32 LRSAM1 MTMR2
6 negative regulation of myelination GO:0031642 9.16 FIG4 MTMR2
7 myelin assembly GO:0032288 8.96 FIG4 MTMR2
8 myelination GO:0042552 8.8 EGR2 MPZ PMP22

Molecular functions related to Tooth Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol-3-phosphatase activity GO:0004438 8.62 FIG4 MTMR2

Sources for Tooth Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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