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MCID: TRT004
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Tourette Syndrome malady |
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16 drugs, 83 genes, 4 tissues, 982 related diseases, 18 phenotypes, 115 articles, clinical trials, genetic tests.
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Sources: 17Genetics Home Reference, 23MedlinePlus, 31NINDS, 15GeneReviews, 22MalaCards See all sources Export this MalaCard |
NINDS: Tourette syndrome (TS) is a neurological disorder characterized by repetitive, stereotyped, involuntary movements and vocalizations
called tics. The first symptoms of TS are almost always noticed in childhood. Some of the more common tics include eye blinking and other vision irregularities, facial grimacing, shoulder shrugging,
and head or shoulder jerking. Perhaps the most dramatic and disabling tics are those that result in self-harm such as punching oneself in the face, or
vocal tics including coprolalia (uttering swear words) or echolalia (repeating the words or phrases of others). Many with TS experience additional neurobehavioral problems including inattention, hyperactivity and impulsivity, and obsessive-compulsive
symptoms such as intrusive thoughts/worries and repetitive behaviors.31
MalaCards: Tourette Syndrome, also known as gilles de la tourette syndrome, is related to gilles de la tourette syndrome and attention deficit hyperactivity disorder. An important gene associated with Tourette Syndrome is CNTNAP2 (contactin associated protein-like 2), and among its related pathways are Tyrosine metabolism p.1 (dopamine) and Tyrosine metabolism p.1 (dopamine). The drugs clonidine and perphenazine and the compounds nicotine and Methotrimeprazine have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and prefrontal cortex, and related mouse phenotypes are taste/olfaction and endocrine/exocrine gland. Genetics Home Reference: Tourette syndrome is a complex disorder characterized by repetitive, sudden, and involuntary movements or noises called tics. Tics usually appear in childhood, and their severity varies over time. In most cases, tics become milder and less frequent in late adolescence and adulthood.17 MedlinePlus: If you have tourette syndrome, you make unusual movements or sounds, called tics. you have little or no control over them. common tics are throat-clearing and blinking. you may repeat words, spin, or, rarely, blurt out swear words. about one of every 100 people has tourette syndrome. it often occurs with other problems, such as attention deficit hyperactivity disorder (adhd) obsessive-compulsive disorder (ocd) anxiety depression the cause of tourette syndrome is unknown. it is more common in boys than girls. the tics usually start in childhood and may be worst in the early teens. many people eventually outgrow them. no treatment is needed unless the tics interfere with everyday life. excitement or worry can make tics worse. calm, focused activities may make them better. medicines and talk therapy may also help. nih: national institute of neurological disorders and stroke23 Wikipedia: Tourette syndrome (also called Tourette\'s syndrome, Tourette\'s disorder, Gilles de la Tourette...44 more... GeneReviews summary for tourette |
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Sources: 2CDC, 15GeneReviews, 16GeneTests, 17Genetics Home Reference, 43UMLS, 7diseasecard, 31NINDS, 33OMIM, 32Novoseek , 23MedlinePlus See all sources |
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for tourette syndrome Drug clinical trials:Search ClinicalTrials for tourette syndrome Search NIH Clinical Center for tourette syndrome Search CenterWatch for tourette syndrome Inferred drug relations via UMLS/NDF-RT:43 28 clonidine, clonidine hcl pwdr [va product], clonidine hydrochloride, haloperidol, haloperidol decanoate, haloperidol lactate, mecamylamine, mecamylamine hydrochloride, pergolide, pergolide mesylate, perphenazine, pimozide, risperidone, ziprasidone, ziprasidone hydrochloride, ziprasidone mesylate |
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Sources: 16GeneTests See all sources |
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to tourette syndrome:22Brain, Cortex, Prefrontal cortex, Caudate nucleus
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to tourette syndrome:25 (show all 18)
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Sources: 35PubMed See all sources |
Articles related to tourette syndrome:(show top 50) (show all 115)
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Sources: 1BioGPS See all sources |
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Sources: 41Thomson Reuters, 10EMD Millipore, 20KEGG, 34PharmGKB, 36QIAGEN, 38Reactome, 3Cell Signaling Technology See all sources |
Pathways related to tourette syndrome according to GeneDecks:(show all 45)
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Sources: 32Novoseek , 34PharmGKB, 9DrugBank, 18HMDB, 42Tocris Bioscience See all sources |
Compounds related to tourette syndrome according to GeneDecks:(show top 50) (show all 357)
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Sources: 12Gene Ontology See all sources |
Cellular components related to tourette syndrome according to GeneDecks:
Biological processes related to tourette syndrome according to GeneDecks:(show top 50) (show all 61)
Molecular functions related to tourette syndrome according to GeneDecks:(show all 11)
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