MCID: TXC001
MIFTS: 30

Toxic Megacolon malady

Gastrointestinal diseases category
Download this MalaCard

Summaries for Toxic Megacolon

About this section


Fully expand this MalaCard
Wikipedia:65 Toxic megacolon (megacolon toxicum) is an acute form of colonic distension. It is characterized by a... more...

MalaCards based summary: Toxic Megacolon, also known as megacolon, toxic, is related to megacolon and colitis. An important gene associated with Toxic Megacolon is TMC1 (transmembrane channel-like 1). Affiliated tissues include colon, bone marrow and bone, and related mouse phenotype behavior/neurological.

Aliases & Classifications for Toxic Megacolon

About this section

Toxic Megacolon, Aliases & Descriptions:

Name: Toxic Megacolon 8 10
 
Megacolon, Toxic 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology8 DOID:1770
SNOMED-CT57 28536002
MeSH34 D008532

Related Diseases for Toxic Megacolon

About this section

Graphical network of the top 20 diseases related to Toxic Megacolon:



Diseases related to toxic megacolon

Symptoms for Toxic Megacolon

About this section

Drugs & Therapeutics for Toxic Megacolon

About this section

Drug clinical trials:

Search ClinicalTrials for Toxic Megacolon

Search NIH Clinical Center for Toxic Megacolon

Genetic Tests for Toxic Megacolon

About this section

Anatomical Context for Toxic Megacolon

About this section

MalaCards organs/tissues related to Toxic Megacolon:

32
Colon, Bone marrow, Bone, Spinal cord, Heart, Smooth muscle, Myeloid

Animal Models for Toxic Megacolon or affiliated genes

About this section

MGI Mouse Phenotypes related to Toxic Megacolon:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053869.1FLOT2, TMC1

Publications for Toxic Megacolon

About this section

Articles related to Toxic Megacolon:

(show top 50)    (show all 222)
idTitleAuthorsYear
1
Unusual Complication of Toxic Megacolon in Typhoid Colitis. (23900751)
2013
2
Toxic megacolon. (22009735)
2012
3
Conservative surgical treatment for toxic megacolon due to Clostridium difficile infection in a transplanted pediatric patient. (22726419)
2012
4
Toxic megacolon due to fulminant Clostridium Difficile colitis. (21861326)
2011
5
Toxic megacolon from hypervirulent Clostridium difficile infection (ribotype 027) following elective total knee replacement: an emerging challenge in modern health care. (22242068)
2010
6
Ulcerative colitis presenting as toxic megacolon. (21189707)
2010
7
Colonic stricture and fistula following haemolytic uraemic syndrome with toxic megacolon. (19899041)
2010
8
Toxic megacolon secondary to Clostridium difficile colitis. Case report. (20423791)
2010
9
Management of acute colitis and toxic megacolon. (22131898)
2010
10
CMV infection in a pregnant woman complicated by toxic megacolon and mesenteric vein thrombosis. (19821211)
2009
11
Toxic megacolon in children with inflammatory bowel disease: clinical and radiographic characteristics. (18510624)
2008
12
Invasive aspergillosis localised to the colon presenting as toxic megacolon. (17328784)
2007
13
A case of toxic megacolon secondary to Clostridium difficile-associated diarrhea worsened after administration of an antimotility agent and molecular analysis of recovered isolates. (17671768)
2007
14
Advances in the diagnosis and management of toxic megacolon. (15776138)
2005
15
Early surgery for the treatment of toxic megacolon. (16172551)
2005
16
Inflammatory pseudopolyposis in a patient with toxic megacolon due to pseudomembranous colitis. (11757676)
2001
17
Factors associated with intestinal perforation in children's non-typhi Salmonella toxic megacolon. (11144376)
2000
18
Campylobacter jejuni-induced severe colitis--a rare cause of toxic megacolon. (10820863)
2000
19
Sub-total colectomy for perforated toxic megacolon in pregnancy. (15512196)
1998
20
Antibiotic-associated fulminant pseudomembranous colitis without toxic megacolon. (1449149)
1992
21
Toxic megacolon and perforation caused by Salmonella. (2302504)
1990
22
Toxic megacolon and perforation caused by Shigella. (2688808)
1989
23
Toxic megacolon and perforation caused by Salmonella. (2765830)
1989
24
Toxic megacolon presenting in the leukocyte scan as distended transverse bowel. (3130613)
1988
25
Toxic megacolon complicating Campylobacter enterocolitis. (3734370)
1986
26
Toxic megacolon due to Campylobacter colitis. (3598315)
1986
27
Toxic megacolon in typhoid fever. (4062466)
1985
28
Toxic megacolon: survival without colectomy (a case report). (6481659)
1984
29
Computerized tomographic demonstration of toxic megacolon: report of a case. (6641190)
1983
30
Toxic megacolon. (6842036)
1983
31
Clostridium difficile in toxic megacolon. (6814650)
1982
32
Clostridium difficile in toxic megacolon complicating acute inflammatory bowel disease. (6809132)
1982
33
Filiform polyposis in Crohn's colitis mimicking toxic megacolon. (7297374)
1981
34
Surgical treatment of toxic megacolon and proposal for a program of therapy. (7425218)
1980
35
Antibiotic-associated pseudomembranous colitis with toxic megacolon: two case reports in children. (7236136)
1980
36
Toxic megacolon in inflammatory bowel disease: a new perspective. (279946)
1978
37
Toxic megacolon--unusual complication of pseudomembranous colitis. (589788)
1977
38
Diagnosis, surgical management and prognosis of toxic megacolon, a complication of ulcerative colitis. (866982)
1977
39
Surgical management of toxic megacolon. (920716)
1977
40
Clindamycin associated pseudomembranous enterocolitis and toxic megacolon. (1245777)
1976
41
Treatment of toxic megacolon. (1251308)
1976
42
Toxic megacolon with perforation. Case report. (4746805)
1973
43
Radiographic evaluation of toxic megacolon in acute ulcerative colitis. (4484006)
1972
44
Toxic megacolon. A surgical disease. (5546331)
1971
45
Surgical treatment of toxic megacolon. Ileostomy and colostomy to prepare patients for colectomy. (5570601)
1971
46
Toxic megacolon. (5774994)
1969
47
Chronic ulcerative colitis complicated by toxic megacolon. (5922036)
1966
48
TOXIC MEGACOLON IN FULMINATING DISEASE. (14250072)
1965
49
Toxic megacolon syndrome of ulcerative colitis. (14007124)
1962
50
Toxic megacolon in ulcerative colitis. (14439404)
1959

Variations for Toxic Megacolon

About this section

Expression for genes affiliated with Toxic Megacolon

About this section
Expression patterns in normal tissues for genes affiliated with Toxic Megacolon

Search GEO for disease gene expression data for Toxic Megacolon.

Pathways for genes affiliated with Toxic Megacolon

About this section

Compounds for genes affiliated with Toxic Megacolon

About this section

GO Terms for genes affiliated with Toxic Megacolon

About this section

Products for genes affiliated with Toxic Megacolon

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Toxic Megacolon

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet