TSS
MCID: TXC005
MIFTS: 63

Toxic Shock Syndrome (TSS) malady

Infectious diseases category

Summaries for Toxic Shock Syndrome

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A commensal bacterial infectious disease that results in infection, has material basis in streptococcus pyogenes or has material basis in staphylococcus aureus , which produce toxins that are absorbed systemically and produce the systemic manifestations. the infection has symptom fever, has symptom rash, has symptom hypotension, has symptom multiorgan failure, has symptom desquamation, has symptom vomiting, has symptom diarrhea, has symptom headache, and has symptom nonfocal neurologic abnormalities.

MalaCards: Toxic Shock Syndrome, also known as shock, toxic, is related to arthritis and peritonitis, and has symptoms including nonfocal neurologic abnormalities, headache and diarrhea. An important gene associated with Toxic Shock Syndrome is IL1B (interleukin 1, beta), and among its related pathways are Leishmaniasis and Senescence and Autophagy. The compounds cycloheximide and indomethacin have been mentioned in the context of this disorder. Affiliated tissues include t cells, monocytes and breast, and related mouse phenotypes are skeleton and hematopoietic system.

Wikipedia:63 Toxic shock syndrome (TSS) is a potentially fatal illness caused by a bacterial toxin. Different... more...

Aliases & Classifications for Toxic Shock Syndrome

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 27ICD9CM, 34MeSH, 56SNOMED-CT, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

toxic shock syndrome 8 10 44
shock, toxic 60
toxic shock 8
tss 8


External Ids:

Disease Ontology8 DOID:14115
ICD9CM27 040.82
MeSH34 D012772
SNOMED-CT56 18504008, 240450004
NCIt39 C35498
ICD1025 A48.3

Related Diseases for Toxic Shock Syndrome

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Toxic Shock Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 287)
idRelated DiseaseScoreTop Affiliating Genes
1arthritis30.8IL1B, IL8, TNF
2peritonitis30.6LACTB, IL1B, CD69, TNF
3rheumatoid arthritis30.6HMGB1, IL1B, IL8, IL1RN, CD69, LTA
4kawasaki disease30.5CIITA
5pneumonia30.5LACTB, HMGB1, IL1B, IL8, KNG1, EDNRA
6down syndrome30.4CCL4
7myositis30.4IL1RN, CIITA
8eosinophilia30.4IL8, CD69, IGHE, IFNG
9mastitis30.3IL1B, IL8
10dermatitis30.3IGHE, IFNG
11pancreatitis30.3IL1B, KNG1, C1S
12meningitis30.3LACTB, IL1B, IL8, CCL4
13influenza30.3LACTB, CD69, LTA, KNG1, CIITA, LBR
14atopic dermatitis30.3IL8, CD69, LTA, IGHE, LBR, TNF
15psoriasis30.3IL1B, IL8, CD69, LTA, CIITA, TNF
16lupus erythematosus30.1C1S
17multiple myeloma30.1CCL3
18wegener's granulomatosis30.1CIITA
19hepatitis30.1LTA, EDNRA
20hepatitis b30.1CIITA, IFNG
21aspergillosis30.1IFNG, CCL3
22measles30.1CIITA, LBR, CCL4
23acute pancreatitis30.1IL8, IL1RN, C1S
24gastritis30.1IL1B, IL8, IL1RN, CCL3
25colorectal cancer30.1HMGB1, EDNRA, LBR
26ischemia30.1CD69, KNG1, CIITA, EDNRA, C1S
27lymphopenia30.1IL1RN, CIITA, LBR, IFNG
28breast cancer30.1HMGB1, CD69, CIITA, CCL3, CCL4
29myeloma30.1IL1B, LTA, MYOM2, IGHE, CIITA, CCL3
30lung cancer30.1HMGB1, KNG1, CIITA, EDNRA, LBR, C1S
31systemic lupus erythematosus30.1IL1RN, CD69, LTA, CIITA, LBR, TNF
32malaria29.9HMGB1, KNG1, TNF, IFNG
33encephalitis29.9HMGB1, IL1B, CIITA, CCL3, CCL4
34adenoma29.9EDNRA
35burns10.7
36fasciitis10.7
37necrotizing fasciitis10.7
38adult syndrome10.6
39vaginitis10.5
40staphylococcal toxic shock syndrome10.5
41exfoliation syndrome10.5
42pyomyositis10.4
43scarlet fever10.4
44tracheitis10.4
45streptococcal toxic-shock syndrome10.4
46breast reconstruction10.3
47pharyngitis10.3
48coronary artery disease10.2
49sudden infant death syndrome10.2
50splenic infarction10.2

Graphical network of the top 20 diseases related to Toxic Shock Syndrome:



Diseases related to toxic shock syndrome

Clinical Features for Toxic Shock Syndrome

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Sources:
8Disease Ontology
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Symptoms:

8 (show all 9)
  • nonfocal neurologic abnormalities
  • headache
  • diarrhea
  • vomiting
  • desquamation
  • multiorgan failure
  • hypotension
  • rash
  • fever

Drugs & Therapeutics for Toxic Shock Syndrome

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Toxic Shock Syndrome

Drug clinical trials:

Search ClinicalTrials for Toxic Shock Syndrome

Search NIH Clinical Center for Toxic Shock Syndrome

Search CenterWatch for Toxic Shock Syndrome

Genetic Tests for Toxic Shock Syndrome

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Anatomical Context for Toxic Shock Syndrome

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32MalaCards
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MalaCards organs/tissues related to Toxic Shock Syndrome:

32
T cells, Monocytes, Breast, Skin, B cells, Testes, Lung, Colon, Bone

Animal Models for Toxic Shock Syndrome or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Toxic Shock Syndrome:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000539010.3IL1B, LTA, EDNRA
2MP:00053979.6CCL3, IFNG, TNF, LBR, EDNRA, CIITA
3MP:00053879.6IL1B, KLRD1, CCL3, IFNG, TNF, LBR
4MP:00053769.4EDNRA, LBR, TNF, IFNG, CCL3, CIITA

Publications for Toxic Shock Syndrome

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Sources:
50PubMed
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Articles related to Toxic Shock Syndrome:

(show top 50)    (show all 604)
idTitleAuthorsYear
1
Recurrent menstrual toxic shock syndrome despite discontinuation of tampon use: is menstrual toxic shock syndrome really caused by tampons? (22897229)
2013
2
Kawasaki shock syndrome presenting as toxic shock syndrome. (23992273)
2013
3
Streptococcal Toxic Shock Syndrome. (24297338)
2013
4
Dye labelled monoclonal antibody assay for detection of Toxic Shock Syndrome Toxin -1 from Staphylococcus aureus. (22530084)
2011
5
Human leukocyte antigen class II transgenic mouse model unmasks the significant extrahepatic pathology in toxic shock syndrome. (21641398)
2011
6
Delayed development of toxic shock syndrome following abdominal tissue expansion in a pediatric reconstruction patient: case report. (20098117)
2010
7
Toxic shock syndrome caused by hospital-acquired methicillin-resistant Staphylococcus aureus in a patient with pancytopenia. (20196714)
2010
8
Group A Streptococcus virulence and host factors in two toddlers with rheumatic fever following toxic shock syndrome. (19828348)
2010
9
Neonatal streptococcal toxic shock syndrome caused by Streptococcus dysgalactiae subsp. equisimilis. (20879096)
2010
10
A fatal case of streptococcal toxic shock syndrome. (18453517)
2008
11
An Australian case of Streptococcus suis toxic shock syndrome associated with occupational exposure to animal carcasses. (18459929)
2008
12
Contamination of reconstituted multidose measles vaccine vial and toxic shock syndrome in Tamilnadu. (18695289)
2008
13
Staphylococcal toxic shock syndrome. (18697637)
2008
14
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. (17505275)
2007
15
A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates. (17375201)
2007
16
Toxic shock syndrome. (18019301)
2007
17
Fulminant fatal toxic shock syndrome with Staphylococcus aureus. (17276828)
2007
18
Streptococcal necrotizing fasciitis with toxic shock syndrome following cervical adenitis. (15302155)
2004
19
Expansion of TcRalphabeta+CD3+CD4-CD8- (CD4/CD8 double-negative) T lymphocytes in a case of staphylococcal toxic shock syndrome. (15034239)
2004
20
Diversity of toxic shock syndrome toxin 1-positive Staphylococcus aureus isolates. (15528567)
2004
21
Severe eosinophilia during the course of toxic shock syndrome. (12940337)
2003
22
Axillary hydroadenitis; an unusual cause of toxic shock syndrome. (15449785)
2003
23
Detection of antibodies to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 using a competitive agglutination inhibition assay. (12753244)
2003
24
Molecular epidemiology of methicillin-resistant Staphylococcus aureus strains causing neonatal toxic shock syndrome-like exanthematous disease in neonatal and perinatal wards. (12843033)
2003
25
Temporal sequence and functional implications of V beta-specific T cell receptor down-regulation and costimulatory molecule expression following in vitro stimulation with the staphylococcal superantigen Toxic shock syndrome toxin-1. (11865410)
2002
26
Double mutant and formaldehyde inactivated TSST-1 as vaccine candidates for TSST-1-induced toxic shock syndrome. (11818153)
2002
27
Multiple splenic infarcts associated with toxic shock syndrome. (11862136)
2002
28
Role of T cells and gamma interferon during induction of hypersensitivity to lipopolysaccharide by toxic shock syndrome toxin 1 in mice. (11179286)
2001
29
Recurrent nonmenstrual toxic shock syndrome: clinical manifestations, diagnosis, and treatment. (11317249)
2001
30
A survey into toxic shock syndrome (TSS) in UK burns units. (10751699)
2000
31
Invasive group A streptococcus infection of the scrotum and streptococcal toxic shock syndrome. (11018632)
2000
32
Cortisol levels and control of inflammatory responses to toxic shock syndrome toxin-1 (TSST-1): the prevalence of night-time deaths in sudden infant death syndrome (SIDS). (10443509)
1999
33
Correlation of temperature and toxicity in murine studies of staphylococcal enterotoxins and toxic shock syndrome toxin 1. (10024605)
1999
34
Exanthematous disease induced by toxic shock syndrome toxin 1 in the early neonatal period. (9620715)
1998
35
Localization of a T-cell epitope of superantigen toxic shock syndrome toxin 1 to residues 125 to 158. (9746605)
1998
36
Novel therapies in streptococcal toxic shock syndrome: attenuation of virulence factor expression and modulation of the host response. (17033393)
1998
37
Induction of selective anergy by toxic shock syndrome toxin-1 in CD8+ T cells. (9415025)
1997
38
Update on canine streptococcal toxic shock syndrome and necrotizing fasciitis. (9105725)
1997
39
Differential induction of Th1 versus Th2 cytokines by group A streptococcal toxic shock syndrome isolates. (9393817)
1997
40
Toxic shock syndrome and necrotizing fasciitis complicating neglected sacrococcygeal pilonidal sinus disease: report of a case. (9369118)
1997
41
Adjunctive treatment of streptococcal toxic shock syndrome using intravenous immunoglobulin: case report and review. (9209207)
1997
42
Toxic shock syndrome and burns. (8774547)
1996
43
Crystal structure of a biologically inactive mutant of toxic shock syndrome toxin-1 at 2.5 A resolution. (8844860)
1996
44
Streptococcal toxic-shock syndrome: spectrum of disease, pathogenesis, and new concepts in treatment. (8903167)
1995
45
Staphylococcal toxic shock syndrome in a paediatric burn unit. (7880413)
1994
46
Case report: streptococcal toxic shock syndrome presenting as septic thrombophlebitis in a child with varicella. (8108215)
1993
47
Defining the group A streptococcal toxic shock syndrome. Rationale and consensus definition. The Working Group on Severe Streptococcal Infections. (8418347)
1993
48
Pyomyositis and probable toxic shock syndrome caused by a toxin-1 producing strain of Staphylococcus aureus. (2495959)
1989
49
Affinity purification of staphylococcal toxic shock syndrome toxin 1 and its pathologic effects in rabbits. (3943896)
1986
50
Clearance of endotoxin from blood of rabbits injected with staphylococcal toxic shock syndrome toxin-1. (3957424)
1986

Genetic Variations for Toxic Shock Syndrome

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Expression for genes affiliated with Toxic Shock Syndrome

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Toxic Shock Syndrome

Search GEO for disease gene expression data for Toxic Shock Syndrome.

Pathways for genes affiliated with Toxic Shock Syndrome

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Sources:
29KEGG, 37NCBI BioSystems Database, 12EMD Millipore, 51QIAGEN, 53Reactome, 52R&D Systems
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Pathways related to Toxic Shock Syndrome according to GeneCards/GeneDecks:

(show all 40)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.4CIITA
210.4IL8
3
Transcription Role of VDR in regulation of genes involved in osteoporosis
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10.4IFNG
410.4IL1B, TNF
5
Hide members
10.3LTA, CCL4
6
Hide members
10.3EDNRA, CCL3
7
Hide members
10.3IL1B, IL8, TNF
810.3TNF, IL8, IL1B
910.3IL1B, TNF, IFNG
1010.3IFNG, TNF, IL1B
1110.3IFNG, TNF, IL1B
12
Hide members
10.3LTA, TNF, IFNG
1310.3IFNG, CIITA, IL1B
1410.3IL1B, TNF, CCL3
1510.3IL8, TNF, IFNG
16
Hide members
10.3IL8, TNF, IFNG
1710.3HMGB1, KNG1, TNF
18
Hide members
10.3CCL4, CCL3, LTA
19
Hide members
10.2IFNG, TNF, LTA, IL1B
2010.2C1S, TNF, IL8, IL1B
2110.2IFNG, TNF, CIITA, IL1B
2210.2IL1B, IL8, IL1RN, TNF
2310.2IL8, CCL3, CCL4
24
Hide members
10.2IFNG, TNF, IL8, IL1B
2510.2IL1B, IL8, TNF, IFNG
26
Hide members
10.2IL1B, IL1RN, CIITA, IFNG
27
Hide members
10.2IL1B, IFNG, CCL3, CCL4
2810.2KLRD1, KLRC1, IFNG, IL8
29
Hide members
10.2CCL4, CCL3, IFNG, TNF
3010.2IFNG, TNF, LTA, IL8, IL1B
31
Hide members
10.2C1S, KLRD1, KLRC1, IGHE
32
Immune response Bacterial infections in normal airways
Hide members
10.2IL1B, IL8, IL1RN, TNF, IFNG
3310.2CCL4, TNF, LTA, IL8, IL1B
34
Hide members
10.1IFNG, TNF, CIITA, LTA, IL8, IL1B
3510.1IL1B, IL8, IFNG, CCL3, CCL4
36
Hide members
10.1KLRD1, KLRC1, IFNG, TNF, IGHE
37
Hide members
10.1CCL4, CCL3, TNF, LTA, IL8, IL1B
38
Hide members
10.1CCL4, CCL3, IFNG, TNF, IL8, IL1B
39
Hide members
10.0IL1B, LTA, CIITA, TNF, IFNG, KLRC1
40
Hide members
9.9C1S, KLRD1, KLRC1, IFNG, CIITA, IGHE

Compounds for genes affiliated with Toxic Shock Syndrome

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Sources:
44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 2BitterDB, 49PharmGKB, 24HMDB
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Compounds related to Toxic Shock Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 151)
idCompoundScoreTop Affiliating Genes
1cycloheximide4410.9LTA
2indomethacin44 59 28 1113.8EDNRA, KNG1
3endotoxin4410.7CIITA, EDNRA, HMGB1
4pentoxifylline44 1111.7IL1RN, LTA, LBR
5hydrocortisone44 2 59 1113.7IL8, IGHE
6gm-csf44 2811.6IFNG, TNF
7prednisolone44 28 1112.6CCL4, LTA, IGHE, EDNRA
8dexamethasone44 49 28 1113.6IGHE, LTA, LBR, EDNRA, CIITA
9fmlp4410.5CCL3, CD69, IL1RN
10gold sodium thiomalate4410.5IL8, IL1B, IFNG, TNF, IL1RN
11mip 1alpha4410.5TNF, CCL4, CCL3, IL8, IL1B
12lipoteichoic acid4410.5CCL3, IL1RN, TNF, LTA, IL8, IL1B
13etanercept44 49 1112.5LTA, C1S, IL8, IFNG, IL1RN, IL1B
14polyinosinic-polycytidylic acid4410.5CIITA, IFNG, TNF, IL8, IL1B, CCL3
15triptolide4410.5IFNG, CCL4, IL1B, CCL3, IL8, TNF
16polymyxin b4410.4IFNG, TNF, IL1RN, IL8, IL1B
17infliximab44 49 1112.4LBR, IL1RN, IFNG, TNF, IGHE, LTA
18poly(i-c)4410.4IFNG, CCL3, CD69, TNF, IL8, IL1B
19peptidoglycan44 2811.4CIITA, IL1B, IL8, IL1RN, CCL4, TNF
20ivig4410.4IL1B, LTA, TNF, IL1RN, CCL4, IGHE
21allergens4410.4CCL4, IFNG, CIITA, IGHE, CD69
22groalpha4410.4IL1B, IL8, CCL4, CCL3, TNF
23ccl344 2811.4IL1B, TNF, CCL4, IFNG, IL8, CCL3
24neopterin4410.4IFNG, IL8, IL1B, CCL3, LBR, LTA
25il 104410.4CCL3, IFNG, TNF, LTA, IL1RN, IL8
26rantes4410.4IFNG, CCL3, CCL4, TNF, LBR, LTA
27budesonide44 49 1112.4TNF, IGHE, IL8, IL1B, IFNG
28tarc4410.4IL8, IGHE, IFNG, CCL4, CCL3, TNF
29l-nmma4410.4CCL3, IFNG, IL1B, TNF, EDNRA, KNG1
30taurine chloramine4410.3IL1B, TNF, IFNG, IL8
31fluticasone propionate44 49 59 1113.3IL1B, IL8, IGHE, TNF, IFNG
32ionomycin4410.3IFNG, CD69, TNF, LBR, KNG1, CCL3
33simvastatin44 49 59 28 11 2415.3IFNG, CCL3, TNF, CIITA, IL1RN, IL8
34leukotriene b444 59 2412.3CCL3, TNF, KNG1, IL1RN, IL8, IL1B
35cyclosporin a44 28 5912.3CCL3, IFNG, LBR, EDNRA, CIITA, IGHE
36oxygen44 2411.2IL8, HMGB1, CIITA, CCL3, EDNRA, TNF
37sb 20358044 5911.2CCL4, IL1RN, HMGB1, IL1B, IL8, TNF
38actinomycin d4410.2IL8, CD69, IL1B, IGHE, KNG1, CIITA
39heparin44 28 11 2413.2C1S, CCL3, HMGB1, IL8, IL1RN, CD69
40toxin-14410.2IL8, IL1B, IL1RN, LTA, KLRC1, CCL4
41histamine44 28 2412.2IL8, IL1B, IL1RN, CCL4, CCL3, IFNG
42herbimycin a44 5911.1IL8, LTA, TNF, IFNG, IL1B, CD69
43prostaglandin4410.1TNF, IL1B, IL1RN, KNG1, CCL4, EDNRA
44vegf4410.1IL1RN, CCL4, CCL3, TNF, EDNRA, IGHE
45serine4410.1CCL3, TNF, CIITA, KNG1, CCL4, IL1RN
46thymidine44 2411.0IFNG, CD69, CIITA, EDNRA, LBR, TNF
47mannose4410.0C1S, CIITA, LTA, CD69, IL1RN, CCL4
48retinoic acid44 2410.9TNF, IL1B, IL1RN, HMGB1, LTA, CCL4
49nitric oxide44 11 2411.9EDNRA, LBR, TNF, IFNG, CCL3, CCL4
50pd 98,059449.7TNF, CCL3, CD69, IL8, IL1B, HMGB1

GO Terms for genes affiliated with Toxic Shock Syndrome

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Sources:
16Gene Ontology
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Cellular components related to Toxic Shock Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00989710.2CD69, TNF, IFNG, KLRD1
2extracellular spaceGO:0056159.7HMGB1, CCL4, CCL3, IFNG, TNF, KNG1
3extracellular regionGO:0055769.5C1S, CCL4, CCL3, IFNG, TNF, KNG1

Biological processes related to Toxic Shock Syndrome according to GeneCards/GeneDecks:

(show all 33)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chronic inflammatory response to antigenic stimulusGO:00287610.7TNF, LTA
2positive regulation of vitamin D biosynthetic processGO:06055710.7IFNG, TNF
3chronic inflammatory response to antigenic stimulusGO:00243910.7TNF, IL1RN
4positive regulation of calcidiol 1-monooxygenase activityGO:06055910.7IL1B, TNF, IFNG
5positive regulation of chemokine biosynthetic processGO:04508010.7IL1B, TNF, IFNG
6sequestering of triglycerideGO:03073010.7IL1B, TNF
7positive regulation of membrane protein ectodomain proteolysisGO:05104410.7IFNG, TNF, IL1B
8negative regulation of growth of symbiont in hostGO:04413010.7LTA, TNF, IFNG
9positive regulation of heterotypic cell-cell adhesionGO:03411610.7IL1B, TNF
10lipopolysaccharide-mediated signaling pathwayGO:03166310.7CCL3, TNF, IL1B
11positive regulation of interferon-gamma productionGO:03272910.6TNF, LTA, IL1B
12positive regulation of fever generationGO:03162210.6TNF, IL1B
13positive regulation of nitric oxide biosynthetic processGO:04542910.6IL1B, TNF, IFNG
14cellular response to organic cyclic compoundGO:07140710.6IL1B, TNF, CCL3
15protein kinase B signaling cascadeGO:04349110.6CCL3, TNF, IL1B
16positive regulation of humoral immune response mediated by circulating immunoglobulinGO:00292510.6LTA, TNF
17humoral immune responseGO:00695910.6LTA, TNF, IFNG
18neutrophil chemotaxisGO:03059310.6CCL3, IFNG, IL8, IL1B
19positive regulation of natural killer cell chemotaxisGO:200050310.6CCL4, CCL3
20positive regulation of interleukin-6 biosynthetic processGO:04541010.6IFNG, IL1B
21calcium-mediated signalingGO:01972210.6CCL3, TNF, IL8
22positive regulation of MHC class II biosynthetic processGO:04534810.6IFNG, CIITA
23MAPK cascadeGO:00016510.5CCL3, TNF, IL1B
24cell activationGO:00177510.5CCL3, TNF
25inflammatory responseGO:00695410.5CCL4, CCL3, TNF, KNG1, IL8, IL1B
26immune responseGO:00695510.4CCL4, CIITA, IGHE, IL1RN, IL8, IL1B
27regulation of I-kappaB kinase/NF-kappaB cascadeGO:04312210.4IL1B, TNF
28regulation of insulin secretionGO:05079610.4IFNG, TNF, IL1B
29cell-cell signalingGO:00726710.3IL1B, LTA, CCL3, CCL4
30negative regulation by host of viral transcriptionGO:04392210.3CCL3, CCL4
31positive regulation of apoptotic processGO:04306510.2TNF, KNG1, LTA, HMGB1
32positive regulation of protein phosphorylationGO:00193410.2IL1B, EDNRA, TNF
33response to drugGO:0424939.9IFNG, TNF, LTA, IL1RN

Molecular functions related to Toxic Shock Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1CCR1 chemokine receptor bindingGO:03172610.3CCL3, CCL4
2CCR5 chemokine receptor bindingGO:03173010.2CCL4, CCL3
3cytokine activityGO:00512510.1HMGB1, IL1B, LTA, TNF, IFNG, CCL4
4chemokine activityGO:0080099.9IL8, CCL3, CCL4

Products for genes affiliated with Toxic Shock Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Toxic Shock Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet