MCID: TRC005
MIFTS: 40

Tracheal Stenosis malady

Summaries for Tracheal Stenosis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Laryngotracheal stenosis refers to abnormal narrowing of the central air passageways. This can occur at... more...

MalaCards: Tracheal Stenosis, also known as stenosis of trachea, is related to thyroiditis and congenital tracheal stenosis. An important gene associated with Tracheal Stenosis is ARSE (arylsulfatase E (chondrodysplasia punctata 1)). The compounds 22-oxacalcitriol and calcium carbonate have been mentioned in the context of this disorder. Affiliated tissues include lymph node, cortex and heart, and related mouse phenotype limbs/digits/tail.

Aliases & Classifications for Tracheal Stenosis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 40NCIt, 57SNOMED-CT, 35MeSH
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Aliases & Descriptions:

tracheal stenosis 8 10 61
stenosis of trachea 8


External Ids:

Disease Ontology8 DOID:3227
NCIt40 C78646
SNOMED-CT57 11296007
MeSH35 D014135

Related Diseases for Tracheal Stenosis

Sources:
17GeneCards, 18GeneDecks
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Diseases in the congenital tracheal stenosis family:

tracheal stenosis

Diseases related to Tracheal Stenosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 66)
idRelated DiseaseScoreTop Affiliating Genes
1thyroiditis30.0TPO
2congenital tracheal stenosis11.1
3tracheal disease10.5
4asthma10.4
5tracheal cancer10.4
6wegener's granulomatosis10.4
7tracheoesophageal fistula10.4
8idiopathic subglottic tracheal stenosis10.4
9congenital tracheomalacia10.3
10relapsing polychondritis10.3
11esophageal atresia10.3
12down syndrome10.3
13tracheal agenesis10.3
14tracheal lymphoma10.2
15trachea carcinoma10.2
16tuberculosis10.2
17lung agenesis10.2
18fibrosing mediastinitis10.2
19burns10.0
20jaccoud's syndrome10.0
21substernal goiter10.0
22carotid stenosis10.0
23subclavian artery aneurysm10.0
24autoimmune thyroiditis10.0
25rubinstein-taybi syndrome10.0
26papillary carcinoma10.0
27systemic lupus erythematosus10.0
28adult t-cell leukemia10.0
29tracheitis10.0
30status asthmaticus10.0
31dextrocardia10.0
32orbital granuloma10.0
33hypercalcemia10.0
34adult syndrome10.0
35adult lymphoma10.0
36patent ductus arteriosus10.0
37adenocarcinoma10.0
38arthritis10.0
39arthropathy10.0
40t-cell leukemia10.0
41thyroid cancer10.0
42urticaria10.0
43vasculitis10.0
44mowat-wilson syndrome10.0
45esophageal atresia/tracheoesophageal fistula10.0
46jung wolff back stahl syndrome10.0
47toriello carey syndrome10.0
48frontometaphyseal dysplasia10.0
49hansen's disease10.0
50hypocomplementemic urticarial vasculitis syndrome10.0

Graphical network of the top 20 diseases related to Tracheal Stenosis:



Diseases related to tracheal stenosis

Clinical Features for Tracheal Stenosis

Drugs & Therapeutics for Tracheal Stenosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Tracheal Stenosis

Drug clinical trials:

Search ClinicalTrials for Tracheal Stenosis

Search NIH Clinical Center for Tracheal Stenosis

Search CenterWatch for Tracheal Stenosis

Genetic Tests for Tracheal Stenosis

Anatomical Context for Tracheal Stenosis

Sources:
33MalaCards
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MalaCards organs/tissues related to Tracheal Stenosis:

33
Lymph node, Cortex, Heart, Liver, Lung, Thyroid, T cells, B cells, Fetal liver, Fetal lung, Trachea, Fetal thyroid

Animal Models for Tracheal Stenosis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Tracheal Stenosis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537110.0ERCC6, IDS

Publications for Tracheal Stenosis

Sources:
51PubMed
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Articles related to Tracheal Stenosis:

(show top 50)    (show all 512)
idTitleAuthorsYear
1
Laryngeal release with slide tracheoplasty for long-segment congenital tracheal stenosis. (24113995)
2013
2
In response to Late complications of nickel-titanium alloy stent in tracheal stenosis. (22965668)
2013
3
Multidetector CT evaluation for the diagnosis of tracheal stenosis occurring shortly after intubation. (23239774)
2012
4
Successful repair of tubercular tracheal stenosis: a rare case report. (21693079)
2011
5
Surgical management of benign tracheal stenosis. (24413853)
2011
6
Unilateral sclerocornea and tracheal stenosis: unusual findings in a patient with Goldenhar anomaly. (22059460)
2011
7
Use of nasopharyngeal airway for interim dilatation of lower tracheal stenosis. (22144942)
2011
8
Tracheal stenosis and adenocarcinoma in an olive baboon (Papio cynocephalus anubis). (22330583)
2011
9
Perioperative management of a patient with a massive lipomatous mediastinal mass, severe cardiomyopathy, and tracheal stenosis for urgent laser bronchoscopy and stent placement. (22137525)
2011
10
Successful treatment of tracheal stenosis by rigid bronchoscopy and topical mitomycin C: a case report. (20150982)
2010
11
Anesthesia for the patient with tracheal stenosis. (20400046)
2010
12
Successful decannulation of T-tubes according to type of tracheal stenosis. (20433025)
2010
13
Flexible bronchoscopic management of benign tracheal stenosis: long term follow-up of 115 patients. (20078894)
2010
14
Congenital tracheal stenosis masquerading as asthma in an adolescent: the value of spirometry. (19224867)
2009
15
When parents opted not to perform surgery for a long-segment congenital tracheal stenosis child: flexible bronchoscopic balloon tracheoplasty as the primary treatment. (19442532)
2009
16
Circumferential calcified tracheal stenosis. (23168602)
2009
17
Modified sliding tracheal plasty using the bridging bronchus for repair of long-segment tracheal stenosis. (18291223)
2008
18
Model of extensive and severe tracheal stenosis in dogs. (19030747)
2008
19
Suction catheter as a low-diameter emergency airway conduit in the setting of severe tracheal stenosis. (18564816)
2008
20
Surgical treatment of benign tracheal stenosis in adults. (20085040)
2008
21
The current state of congenital tracheal stenosis. (17712567)
2007
22
The use of rigid bronchoscopy for bronchial stenting in patients with tracheal stenosis. (17418761)
2007
23
The role of conservative management in congenital tracheal stenosis: an evidence-based long-term follow-up study. (16818049)
2006
24
Bilateral independent high-frequency jet ventilation for intra-operative airway management of repair of congenital tracheal stenosis. (17063577)
2006
25
Is tracheal stenosis caused by percutaneous tracheostomy different from that by surgical tracheostomy? (15764771)
2005
26
A new technique for T-tube insertion in tracheal stenosis located above the tracheal stoma. (16305925)
2005
27
Subglottic tracheal stenosis as primary manifestation of a marginal zone B-cell lymphoma of the larynx. (15875774)
2005
28
Tracheal stenosis aftertracheostomy or intubation: review with special regard to cause and management. (16107105)
2005
29
Diagnosis and management of tracheal stenosis. (16432969)
2004
30
Tracheal resection with end-to-end anastomosis for benign tracheal stenosis. (15330139)
2004
31
Successful treatment of long-segmental tuberculous tracheal stenosis with combined Mongomery T-stent and Hood stent. (17670257)
2004
32
Slide tracheoplasty for congenital tracheal stenosis. (14694365)
2004
33
Vascular-pedicled costal cartilage graft for the treatment of subglottic and upper tracheal stenosis. (15616924)
2004
34
Chronic subglottic and tracheal stenosis: endoscopic management vs. surgical reconstruction. (12682844)
2003
35
Subglottic tracheal stenosis in pregnancy: anaesthetic implications. (14601284)
2003
36
Successful use of laryngeal mask airway for a patient with tracheal stenosis with tracheobronchopathia osteochondroplastica. (12198074)
2002
37
Congenital tracheal stenosis treated with dilatation. (11428283)
2001
38
Tracheal stenosis and congenital heart disease in patients with Down syndrome: diagnostic approach and surgical options. (10967384)
2000
39
Recurrent psychogenic coma following tracheal stenosis repair. (10555701)
1999
40
Management of distal tracheal stenosis. (10190806)
1999
41
Congenital tracheal stenosis in a patient with Down's syndrome. (9220530)
1997
42
Experience in tracheobronchial reconstruction with a costal cartilage graft for congenital tracheal stenosis. (9021569)
1997
43
Severe tracheal stenosis and operative delivery. (7702139)
1995
44
Imaging of laryngeal and tracheal stenosis. (8525829)
1995
45
Late recurrence of Wegener's granulomatosis presenting as tracheal stenosis in a renal transplant patient. (8136569)
1994
46
Unexpected congenital tracheal stenosis in infants with congenital heart disease. (8317737)
1993
47
Postintubation tracheal stenosis: diagnosis and management. (8256133)
1993
48
Resection of tracheal stenosis with end-to-end anastomosis. (8373088)
1993
49
Aberrant left pulmonary artery with tracheal stenosis without vascular sling. (1997984)
1991
50
Tracheoplasty for congenital long-segment intrathoracic tracheal stenosis. (2003703)
1991

Genetic Variations for Tracheal Stenosis

Expression for genes affiliated with Tracheal Stenosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Tracheal Stenosis

Search GEO for disease gene expression data for Tracheal Stenosis.

Pathways for genes affiliated with Tracheal Stenosis

Compounds for genes affiliated with Tracheal Stenosis

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 24HMDB, 2BitterDB, 60Tocris Bioscience
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Compounds related to Tracheal Stenosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
122-oxacalcitriol4510.1PTHLH, CD36
2calcium carbonate4510.1CD36, PTHLH
3tartrate4510.0PTHLH, CD36
4pamidronate45 50 1111.9PTHLH, CD36
5hydroxyproline45 11 2411.8PTHLH, CD36, FBN1
6sodium dodecylsulfate459.8TPO, PTHLH, FBN1
7clodronate45 50 1111.6PTHLH, CD36
8tgf beta1459.6PTHLH, CD36, FBN1
9hydrocortisone45 2 60 1112.6CD36, PTHLH, TPO
10steroid459.5IDS, ARSE, PGRMC1, PTHLH, TPO

GO Terms for genes affiliated with Tracheal Stenosis

Sources:
16Gene Ontology
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Cellular components related to Tracheal Stenosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1microfibrilGO:0015279.9ADAMTS10, FBN1

Biological processes related to Tracheal Stenosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1skeletal system developmentGO:0015019.7PTHLH, FBN1, ARSE

Products for genes affiliated with Tracheal Stenosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Tracheal Stenosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet