MCID: TRC005
MIFTS: 33

Tracheal Stenosis malady

Respiratory diseases, Rare diseases, Fetal diseases categories

Aliases & Classifications for Tracheal Stenosis

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Aliases & Descriptions for Tracheal Stenosis:

Name: Tracheal Stenosis 10 12 65 36
 
Stenosis of Trachea 10


Classifications:



External Ids:

Disease Ontology10 DOID:3227
MeSH36 D014135
SNOMED-CT59 11296007
NCIt42 C78646

Summaries for Tracheal Stenosis

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MalaCards based summary: Tracheal Stenosis, also known as stenosis of trachea, is related to congenital tracheal stenosis and laryngitis. An important gene associated with Tracheal Stenosis is ADAMTSL2 (ADAMTS-Like 2), and among its related pathways is O-linked glycosylation. Affiliated tissues include trachea, heart and lung.

Related Diseases for Tracheal Stenosis

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Diseases in the Tracheal Stenosis family:

Congenital Tracheal Stenosis

Diseases related to Tracheal Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 106)
idRelated DiseaseScoreTop Affiliating Genes
1congenital tracheal stenosis11.1
2laryngitis10.7
3esophagitis10.6
4tracheomalacia10.5
5congenital heart disease10.4
6mediastinitis10.4
7idiopathic subglottic tracheal stenosis10.4
8tracheoesophageal fistula10.4
9asthma10.4
10cervicitis10.4
11burns10.4
12relapsing polychondritis10.4
13aneurysm10.4
14esophageal cancer10.3
15tetralogy of fallot10.3
16geleophysic dysplasia 110.3
17esophageal atresia10.3
18down syndrome10.3
19goiter10.3
20thyroiditis10.3
21tuberculosis10.3
22jung wolff back stahl syndrome10.3
23lung cancer10.2
24hydrolethalus syndrome10.2
25frontometaphyseal dysplasia10.2
26laryngotracheitis10.2
27thyroid cancer10.2
28fibrosing mediastinitis10.2
29lung agenesis10.2
30genetic prion diseases10.1ADAMTSL2, FBN1
31rheumatoid arthritis10.1
32systemic lupus erythematosus10.1
33mowat-wilson syndrome10.1
34larsen syndrome10.1
35mucopolysaccharidosis ih/s10.1
36fraser syndrome10.1
37chops syndrome10.1
38pendred syndrome10.1
39pfeiffer syndrome10.1
40cartilage-hair hypoplasia10.1
41smith-lemli-opitz syndrome10.1
42keutel syndrome10.1
43kniest dysplasia10.1
44geleophysic dysplasia 210.1
45rubinstein-taybi syndrome10.1
46tetra-amelia syndrome10.1
47microcephalic osteodysplastic primordial dwarfism, type ii10.1
48chondrodysplasia punctata, x-linked dominant10.1
49craniofacioskeletal syndrome10.1
50mucopolysaccharidosis ii10.1

Graphical network of the top 20 diseases related to Tracheal Stenosis:



Diseases related to tracheal stenosis

Symptoms for Tracheal Stenosis

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Drugs & Therapeutics for Tracheal Stenosis

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Drugs for Tracheal Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1cadexomer iodinePhase 2425
2
IodinePhase 24597553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
3Mitomycins208
4CalamusNutraceutical312

Interventional clinical trials:

(show all 16)
idNameStatusNCT IDPhase
1Clinical Trial of Stem Cell Based Tissue Engineered Laryngeal ImplantsRecruitingNCT01977911Phase 1, Phase 2
2Airway and/or Pulmonary Vessels TransplantationRecruitingNCT01331863Phase 1, Phase 2
3A Trail of a Novel Tracheal Radioactive Stent for the Malignant Airway ObstructionRecruitingNCT02565927Phase 2
4Matrix Biology of Tracheobronchomalacia and Tracheal StenosisCompletedNCT00705848
5Factors to Obstructive Granulation Tissue Formation After Ultraflex Stenting in Benign Tracheal NarrowingCompletedNCT01006200
6"Cuffed Versus Uncuffed Tracheal Tubes in Small Children"CompletedNCT00221377
7Study of Mitomycin-C Application in Laryngotracheal StenosisRecruitingNCT01523275
8trūFreeze® Spray Cryotherapy Patient RegistryRecruitingNCT01802203
9Treatment Alternatives in iSGS (NoAAC PR-02 Study)RecruitingNCT02481817
10Endoscopic Evaluation of the Paediatric Airway After Prior Prolonged (>24 h) Tracheal IntubationRecruitingNCT02350933
11Efficacy and Safety Evaluation of HCPA-1 Silicone Stent in the Treatment of Central Airway ObstructionsRecruitingNCT01389531
12Biodegradable Stents in the Management of Stenoses of the Large AirwaysActive, not recruitingNCT02620319
13Comparison of Intubation Conditions Between the Gliderite and the S-GuideNot yet recruitingNCT02519647
14MRI Review of Tracheal DimensionsTerminatedNCT00277953
15Ventilator Associated Pneumonia and Late Complications of Percutaneous TracheostomyTerminatedNCT00184925
16Office-based Radial Expansion Balloon Dilation of the Esophagus and TracheaWithdrawnNCT00583960

Search NIH Clinical Center for Tracheal Stenosis


Cochrane evidence based reviews: Tracheal Stenosis

Genetic Tests for Tracheal Stenosis

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Anatomical Context for Tracheal Stenosis

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MalaCards organs/tissues related to Tracheal Stenosis:

33
Trachea, Heart, Lung, Thyroid, B cells, Cortex, T cells

Animal Models for Tracheal Stenosis or affiliated genes

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Publications for Tracheal Stenosis

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Articles related to Tracheal Stenosis:

(show top 50)    (show all 551)
idTitleAuthorsYear
1
Modified end-to-end anastomosis for the treatment of congenital tracheal stenosis with a bridging bronchus. (25555968)
2015
2
Palliation of Post-intubation Tracheal Stenosis Using Insulation-Tipped Diathermic Knife 2: A Case Report. (26390388)
2015
3
Pulmonary Artery Sling Causing Tracheal Stenosis in a Neonate. (26504454)
2015
4
Successful excision of a giant mediastinal vagal schwannoma causing severe tracheal stenosis through a median sternotomy. (24996720)
2014
5
Severe tracheal stenosis with tracheopathia osteoplastica-like changes due to traumatic blunt injury. (25530868)
2014
6
Metallic expandable stents in the management of malignant tracheal stenosis due to esophageal cancer with lymph node metastasis. (24179541)
2013
7
Circumferential tracheal resection with primary anastomosis for post-intubation tracheal stenosis: study of 24 cases. (23397061)
2013
8
Using Proseal LMA and I-gel for difficult airway management in patient with diffuse tracheal stenosis and pulmonary artery sling. (23822629)
2013
9
An unusual cause of tracheal stenosis: diagnosis and management? Tracheopathia osteochondroplastica. (22445497)
2012
10
A model of canine tracheal stenosis induced by radiofrequency cauterization. (22136742)
2012
11
Severe tracheal stenosis secondary to advanced esophageal cancer. (21354759)
2012
12
Utility of rigid bronchoscopic dilatation and mitomycin C application in the management of postintubation tracheal stenosis: case series and systematic review of literature. (23207530)
2012
13
Induction of tracheal stenosis in a rabbit model-endoscopic versus open technique. (21344426)
2011
14
An Unusual Presentation of a Case of Tracheal stenosis. (21804720)
2011
15
Emergency airway management of a patient with tracheal stenosis. (21381592)
2010
16
Successful treatment of tracheal stenosis by rigid bronchoscopy and topical mitomycin C: a case report. (20150982)
2010
17
Multimodal imaging guidance for laser ablation in tracheal stenosis. (20593421)
2010
18
Case report: respiratory inductance plethysmography as a monitor of ventilation during laser ablation and balloon dilatation of subglottic tracheal stenosis. (19907193)
2009
19
Aortopexy for tracheomalacia with dextrocardia, pulmonary artery sling, and congenital tracheal stenosis. (19766841)
2009
20
Congenital tracheal stenosis masquerading as asthma in an adolescent: the value of spirometry. (19224867)
2009
21
Benign tracheal stenosis: a case series analysis. (23168589)
2009
22
Expandable metal stents as an alternative treatment of cuff-related tracheal stenosis in tracheostomy-dependent ventilated patients: a prospective study of nine cases and description of the complications. (17089175)
2007
23
Prognostic factors in the surgical treatment of congenital tracheal stenosis: a multicenter analysis of the literature. (16410137)
2006
24
Is tracheal stenosis caused by percutaneous tracheostomy different from that by surgical tracheostomy? (15764771)
2005
25
Long-term management of extensive tracheal stenosis due to formic acid chemical burn. (15942303)
2005
26
Stents and sensibility--use of the Montgomery T-tube in tracheal stenosis. (15519218)
2004
27
Chronic subglottic and tracheal stenosis: endoscopic management vs. surgical reconstruction. (12682844)
2003
28
Endoscopically placed expandable metal tracheal stents for the management of complicated tracheal stenosis. (12579481)
2003
29
Esophageal atresia associated with tracheal stenosis and right lung agenesis: report of one case. (12632790)
2002
30
Patterns of cartilage structural protein loss in human tracheal stenosis. (12160268)
2002
31
Congenital tracheal stenosis treated with dilatation. (11428283)
2001
32
Mask induction with sevoflurane in a parturient with severe tracheal stenosis. (11506134)
2001
33
Surgical management of idiopathic subglottic tracheal stenosis. (10773576)
2000
34
Perioperative extracorporeal membrane oxygenation for tracheal reconstruction in congenital tracheal stenosis. (10663850)
2000
35
Congenital Heart Surgery Nomenclature and Database Project: vascular rings, tracheal stenosis, pectus excavatum. (10798437)
2000
36
Systemic lupus erythematosus and tracheal stenosis. (10084030)
1999
37
A case of follicular thyroid cancer with tracheal stenosis responded to external radiation therapy. (10378657)
1999
38
Tracheoplasty in congenital tracheal stenosis. (9720677)
1998
39
Congenital tracheal stenosis in a patient with Down's syndrome. (9220530)
1997
40
Anterior pericardial tracheoplasty for congenital tracheal stenosis: intermediate to long-term outcomes. (8823076)
1996
41
Correlation between functional, radiological and anatomical abnormalities in upper airway obstruction (UAO) due to tracheal stenosis. (8525830)
1995
42
Failure of the laryngeal mask airway (LMA) to ventilate patients with severe tracheal stenosis. (7481098)
1995
43
Slide tracheoplasty for long-segment congenital tracheal stenosis. (7944680)
1994
44
Tracheal stenosis and autoimmune thyroiditis]. (8079247)
1994
45
Congenital tracheal stenosis. The otolaryngologist's perspective. (8166979)
1994
46
Factors that influence successful decannulation after surgery for laryngo-tracheal stenosis in children. (7836031)
1994
47
Congenital tracheal stenosis: a report of two cases. (8364781)
1993
48
Tracheal stenosis in feedlot cattle. (8373863)
1993
49
Resection for congenital tracheal stenosis. (1929986)
1991
50
MRI in tracheal stenosis by innominate artery in children. (2027731)
1991

Variations for Tracheal Stenosis

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Expression for genes affiliated with Tracheal Stenosis

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Search GEO for disease gene expression data for Tracheal Stenosis.

Pathways for genes affiliated with Tracheal Stenosis

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Pathways related to Tracheal Stenosis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
8.9ADAMTS10, ADAMTS17, ADAMTSL2

GO Terms for genes affiliated with Tracheal Stenosis

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Cellular components related to Tracheal Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1microfibrilGO:000152710.2ADAMTS10, FBN1
2extracellular matrixGO:00310128.5ADAMTS10, ADAMTS17, ADAMTSL2, FBN1
3proteinaceous extracellular matrixGO:00055788.4ADAMTS10, ADAMTS17, ADAMTSL2, FBN1

Biological processes related to Tracheal Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1proteolysisGO:00065088.9ADAMTS10, ADAMTS17, ADAMTSL2

Molecular functions related to Tracheal Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1metalloendopeptidase activityGO:00042229.1ADAMTS10, ADAMTS17, ADAMTSL2
2peptidase activityGO:00082338.9ADAMTS10, ADAMTS17, ADAMTSL2

Sources for Tracheal Stenosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet