MCID: TRC040
MIFTS: 41

Tracheoesophageal Fistula malady

Category: Rare diseases

Aliases & Classifications for Tracheoesophageal Fistula

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Aliases & Descriptions for Tracheoesophageal Fistula:

Name: Tracheoesophageal Fistula 47 26 49
Tracheoesophageal Fistula with or Without Esophageal Atresia 47
 
Te Fistula 47
Tef 47

Classifications:



Summaries for Tracheoesophageal Fistula

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Wikipedia:70 A tracheoesophageal fistula (TEF, or TOF; see spelling differences) is an abnormal connection (fistula)... more...

MalaCards based summary: Tracheoesophageal Fistula, also known as tracheoesophageal fistula with or without esophageal atresia, is related to imperforate anus and esophageal atresia/tracheoesophageal fistula. An important gene associated with Tracheoesophageal Fistula is SHH (Sonic Hedgehog). Affiliated tissues include trachea, lung and thyroid, and related mouse phenotypes are taste/olfaction and craniofacial.

Related Diseases for Tracheoesophageal Fistula

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Diseases related to Tracheoesophageal Fistula via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1imperforate anus29.0CHD7, NOG, SHH
2esophageal atresia/tracheoesophageal fistula12.5
3pancreatic hypoplasia, intestinal atresia, and gallbladder aplasia or hypoplasia, with or without tracheoesophageal fistula12.0
4tracheoesophageal fistula with or without esophageal atresia12.0
5tracheoesophageal fistula symphalangism12.0
6feingold syndrome11.3
7vater/vacterl association11.3
8vater association with macrocephaly and ventriculomegaly11.2
9vacterl association, x-linked11.2
10mitchell-riley syndrome11.0
11fanconi anemia, complementation group b11.0
12feingold syndrome 211.0
13esophagitis10.9
14esophageal atresia10.8
15laryngitis10.1
16duodenitis10.1
17melanotic medulloblastoma10.1PTEN, SHH
18duodenal atresia10.1
19lymphoma10.1
20tracheomalacia10.1
21tracheal stenosis10.1
22esophageal cancer10.1
23epithelioid leiomyosarcoma10.0PTEN, ZIC3
24cervicitis10.0
25congenital diaphragmatic hernia10.0
26tracheal agenesis10.0
27tsc1-related lymphangioleiomyomatosis10.0HOXD13, SHH
28lung cancer10.0
29hypertrophic pyloric stenosis10.0
30pyloric stenosis10.0
31mediastinitis10.0
32right aortic arch10.0
33behcet syndrome9.9HOXD13, ZIC3
34gastroesophageal reflux9.9
35respiratory failure9.9
36thyroiditis9.9
37laryngeal cleft9.9
38ischemic bone disease9.9HOXD13, NOG
39aspergillosis9.8
40tricuspid atresia9.8
41aspiration pneumonia9.8
42dermatomyositis9.8
43microcephaly9.8
44heart disease9.8
45pneumonia9.8
46achalasia9.8
47congenital tracheal stenosis9.8
48dysphagia9.8
49ichthyosis lamellar 19.8PTEN, ZIC3
50serous conjunctivitis except viral9.8HOXD13, NOG

Graphical network of the top 20 diseases related to Tracheoesophageal Fistula:



Diseases related to tracheoesophageal fistula

Symptoms for Tracheoesophageal Fistula

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Drugs & Therapeutics for Tracheoesophageal Fistula

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Drugs for Tracheoesophageal Fistula (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1threonineNutraceutical20

Interventional clinical trials:

idNameStatusNCT IDPhase
1Endoscopic Closure of Tracheoesophageal Fistulas With Occluder DeviceTerminatedNCT01153061Phase 4
2Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood GasesUnknown statusNCT01467245
3Trichloroacetic Acid for Endoscopic Tracho-esophageal Fistula RepairUnknown statusNCT01287312
4National Register of Oesophageal AtresiaRecruitingNCT02883725
5Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic SurgeryEnrolling by invitationNCT02033772
6A Physiological Study to Determine the Enteral Threonine Requirements in Infants Aged 1 to 6 MonthsEnrolling by invitationNCT02364843
7Chewing in Children With Repaired Esophageal Atresia-tracheoesophageal FistulaNot yet recruitingNCT03026491

Search NIH Clinical Center for Tracheoesophageal Fistula

Genetic Tests for Tracheoesophageal Fistula

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Genetic tests related to Tracheoesophageal Fistula:

id Genetic test Affiliating Genes
1 Tracheoesophageal Fistula26

Anatomical Context for Tracheoesophageal Fistula

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MalaCards organs/tissues related to Tracheoesophageal Fistula:

35
Trachea, Lung, Thyroid, Colon, Bone, Heart, Testes

Animal Models for Tracheoesophageal Fistula or affiliated genes

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MGI Mouse Phenotypes related to Tracheoesophageal Fistula:

40 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.8NOG, PTEN, SHH
2MP:00053829.3CHD7, NOG, SHH, ZIC3
3MP:00053779.3CHD7, NOG, SHH, ZIC3
4MP:00107719.1HOXD13, NOG, PTEN, SHH
5MP:00053679.1HOXD13, NOG, PTEN, SHH
6MP:00053858.8CHD7, NOG, PTEN, SHH, ZIC3
7MP:00053848.8CHD7, NOG, PTEN, SHH, ZIC3
8MP:00036318.8CHD7, NOG, PTEN, SHH, ZIC3
9MP:00053888.7CHD7, NOG, PTEN, SHH, ZIC3
10MP:00053798.6CHD7, HOXD13, NOG, PTEN, SHH
11MP:00053698.6CHD7, HOXD13, NOG, PTEN, SHH
12MP:00053818.0CHD7, HOXD13, NOG, PTEN, SHH, ZIC3
13MP:00053808.0CHD7, HOXD13, NOG, PTEN, SHH, ZIC3
14MP:00053788.0CHD7, HOXD13, NOG, PTEN, SHH, ZIC3
15MP:00053718.0CHD7, HOXD13, NOG, PTEN, SHH, ZIC3
16MP:00107688.0CHD7, HOXD13, NOG, PTEN, SHH, ZIC3
17MP:00053897.9CHD7, HOXD13, NOG, PTEN, SHH, ZIC3
18MP:00053907.9CHD7, HOXD13, NOG, PTEN, SHH, ZIC3
19MP:00053917.1CHD7, HOXD13, NOG, PTEN, SHH, ZIC3

Publications for Tracheoesophageal Fistula

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Articles related to Tracheoesophageal Fistula:

(show top 50)    (show all 621)
idTitleAuthorsYear
1
Preliminary Study of Video-Based Pediatric Endoscopic Surgical Skill Assessment Using a Neonatal Esophageal Atresia/Tracheoesophageal Fistula Model. (27858521)
2017
2
Tracheoesophageal fistula induced by invasive pulmonary aspergillosis. (27761449)
2016
3
Late presenting iatrogenic tracheoesophageal fistula. (26936836)
2016
4
Thoracoscopic Esophageal Atresia with Tracheoesophageal Fistula Repair: The First Iranian Group Report, Passing the Learning Curve. (27471677)
2016
5
Endoscopic closure of tracheoesophageal fistula with submucosal dissection and a biosynthetic mesh. (26115391)
2015
6
Long-term esophageal and respiratory outcomes in children with esophageal atresia and tracheoesophageal fistula. (26475129)
2015
7
Thoracoscopic repair of esophageal atresia with tracheoesophageal fistula: overcoming the learning curve. (25475795)
2014
8
Recurrent tracheoesophageal fistula. (23720208)
2013
9
Thoracoscopic treatment of congenital esophageal stenosis in combination with H-type tracheoesophageal fistula. (22901927)
2012
10
Comparison of neonatal tolerance to thoracoscopic and open repair of esophageal atresia with tracheoesophageal fistula. (23044311)
2012
11
Congenital tracheoesophageal fistula. (22272674)
2012
12
Congenital pulmonary airway malformation (CPAM) [congenital cystic adenomatoid malformation] associated with tracheoesophageal fistula and agensesis of the corpus callosum. (22414029)
2012
13
Slide tracheoplasty in an infant with congenital tracheal stenosis and oesophageal atresia with tracheoesophageal fistula. (22689186)
2012
14
Usefulness of dextranomer/hyaluronic acid copolymer in bronchoscopic treatment of recurrent tracheoesophageal fistula in children. (21782257)
2011
15
Tracheoesophageal fistula closed by chemoradiotherapy in lung cancer. (21769294)
2011
16
Difficult airway caused by remnant tracheal cleft after tracheoesophageal fistula repair. (21441791)
2011
17
Incidence, diagnosis, and outcomes of vocal fold immobility after esophageal atresia (EA) and/or tracheoesophageal fistula (TEF) repair. (22169990)
2011
18
Esophageal atresia/tracheoesophageal fistula complicated by hypertrophic pyloric stenosis: a case report. (20113643)
2010
19
An 18-year experience of tracheoesophageal fistula and esophageal atresia. (21189942)
2010
20
Congenital tracheoesophageal fistula in an elderly patient with thoracic empyema. (19908119)
2009
21
Feingold syndome: a rare but important cause of syndromic tracheoesophageal fistula. (17848225)
2007
22
Endoscopic management of recurrent congenital tracheoesophageal fistula: a review of techniques and results. (17408757)
2007
23
Anesthetic management of tracheoesophageal fistula repair in a newborn with hypoplastic left heart syndrome. (16677272)
2006
24
Faulty bone morphogenetic protein signaling in esophageal atresia with tracheoesophageal fistula. (16818050)
2006
25
Bone morphogenetic protein expression patterns in human esophageal atresia with tracheoesophageal fistula. (16315037)
2006
26
Preoperative catheterization of H-type tracheoesophageal fistula to facilitate its localization and surgical correction. (16544220)
2006
27
Esophageal atresia with double tracheoesophageal fistula--a case report and review of the literature. (16254849)
2005
28
Appendiceal mass in a neonate after surgery for esophageal atresia and tracheoesophageal fistula: report of a case. (15622470)
2005
29
Thoracoscopic repair of H-type tracheoesophageal fistula in the newborn: a technical case report. (15486907)
2004
30
A bifurcated tracheal tube for a neonate with tracheoesophageal fistula. (15108992)
2004
31
Tracheoesophageal fistula caused by ingestion of a caustic substance. (12789756)
2003
32
Recurrent tracheoesophageal fistula after foreign body impaction. (12811481)
2003
33
Management of a difficult malignant tracheoesophageal fistula. (17670152)
2003
34
Management of an acquired tracheoesophageal fistula with a fascial free flap. (12112560)
2002
35
Tracheoesophageal fistula after blunt chest trauma: successful diagnosis by computed tomography. (11028712)
2000
36
Tracheoesophageal fistula caused by a self-expanding esophageal stent. (10215238)
1999
37
Simplifying the Waterston's stratification of infants with tracheoesophageal fistula. (10515532)
1999
38
Esophageal patching for an unsuturable tracheoesophageal fistula. (9845151)
1998
39
Esophageal atresia and tracheoesophageal fistula: success and failure rates in the United Arab Emirates. (9880753)
1998
40
Split pectoralis major flap for massive tracheoesophageal fistula. (9419118)
1997
41
Elective, postoperative ventilation in the management of esophageal atresia and tracheoesophageal fistula. (9099641)
1997
42
Prognostic classification for esophageal atresia and tracheoesophageal fistula: Waterston versus Montreal. (9247237)
1997
43
Esophageal duplication cyst with esophageal web and tracheoesophageal fistula. (8811570)
1996
44
Coexisting left congenital diaphragmatic hernia and esophageal atresia with tracheoesophageal fistula: successful management in a premature neonate. (8811578)
1996
45
Use of an intratracheal silicone prosthesis (Dumon type) for the treatment of tracheoesophageal fistula due to advanced lung cancer. (8931224)
1996
46
Bronchoscopy and occlusion of tracheoesophageal fistula. (8638821)
1996
47
Radiology rounds. Tracheoesophageal fistula. (7787487)
1995
48
Recurrent tracheoesophageal fistula treated with fibrin glue. (7877030)
1994
49
Tracheoesophageal fistula caused by mycobacterial tuberculosis adenopathy. (8512414)
1993
50
Ectopic unilateral multicystic kidney in infant. Associated anomalies of tracheoesophageal fistula and annular pancreas. (14423160)
1960

Variations for Tracheoesophageal Fistula

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Expression for genes affiliated with Tracheoesophageal Fistula

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Search GEO for disease gene expression data for Tracheoesophageal Fistula.

Pathways for genes affiliated with Tracheoesophageal Fistula

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GO Terms for genes affiliated with Tracheoesophageal Fistula

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Biological processes related to Tracheoesophageal Fistula according to GeneCards Suite gene sharing:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1somite developmentGO:006105310.3NOG, SHH
2lung morphogenesisGO:006042510.2NOG, SHH
3negative regulation of cardiac muscle cell proliferationGO:006004410.2NOG, PTEN
4dorsal/ventral pattern formationGO:000995310.1NOG, SHH
5embryonic hindlimb morphogenesisGO:003511610.0CHD7, SHH
6camera-type eye developmentGO:004301010.0CHD7, SHH
7anatomical structure formation involved in morphogenesisGO:004864610.0NOG, SHH
8canonical Wnt signaling pathwayGO:006007010.0PTEN, SHH
9embryonic skeletal system developmentGO:004870610.0NOG, SHH
10palate developmentGO:00600219.9CHD7, SHH
11lung developmentGO:00303249.8SHH, ZIC3
12heart loopingGO:00019479.8SHH, ZIC3
13male genitalia developmentGO:00305399.7HOXD13, SHH
14determination of left/right symmetryGO:00073689.6SHH, ZIC3
15embryonic limb morphogenesisGO:00303269.6HOXD13, SHH
16somatic stem cell population maintenanceGO:00350199.6NOG, ZIC3
17limb developmentGO:00601739.6CHD7, NOG, SHH
18locomotory behaviorGO:00076269.4CHD7, PTEN
19embryonic digit morphogenesisGO:00427339.3HOXD13, NOG, SHH
20negative regulation of cell migrationGO:00303369.2NOG, PTEN, SHH
21anterior/posterior pattern specificationGO:00099529.1HOXD13, SHH, ZIC3
22skeletal system developmentGO:00015019.0CHD7, HOXD13, NOG
23central nervous system developmentGO:00074178.7CHD7, NOG, PTEN, SHH
24pattern specification processGO:00073898.6HOXD13, NOG, SHH, ZIC3
25positive regulation of transcription from RNA polymerase II promoterGO:00459447.3CHD7, HOXD13, NOG, SHH, ZIC3

Molecular functions related to Tracheoesophageal Fistula according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:00009788.5CHD7, HOXD13, ZIC3

Sources for Tracheoesophageal Fistula

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet