MCID: TRN030
MIFTS: 36

Transient Erythroblastopenia of Childhood malady

Genetic diseases, Rare diseases, Immune diseases, Blood diseases categories

Aliases & Classifications for Transient Erythroblastopenia of Childhood

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Sources:
49OMIM, 11diseasecard, 45NIH Rare Diseases, 51Orphanet, 65UMLS, 47Novoseek, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Transient Erythroblastopenia of Childhood:

Name: Transient Erythroblastopenia of Childhood 49 11 45 51 65
Transient Acquired Pure Red Cell Aplasia 51 65
Erythroblastopenia, Transient 45 47
 
Familial Transient Erythroblastopenia of Childhood 45
Tec 45


Classifications:



External Ids:

OMIM49 227050
Orphanet51 98871
ICD10 via Orphanet28 D60.1
MESH via Orphanet37 C536980
UMLS via Orphanet66 C0238478
ICD1027 D60.1

Summaries for Transient Erythroblastopenia of Childhood

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OMIM:49 Transient erythroblastopenia of childhood is a pure red cell aplasia that occurs in a previously healthy child, most... (227050) more...

MalaCards based summary: Transient Erythroblastopenia of Childhood, also known as transient acquired pure red cell aplasia, is related to aplastic anemia and chondrosarcoma, and has symptoms including autosomal recessive inheritanceand transient erythroblastopenia. An important gene associated with Transient Erythroblastopenia of Childhood is TEC (Tec Protein Tyrosine Kinase), and among its related pathways are FCERI mediated Ca+2 mobilization and Osteoclast differentiation. Affiliated tissues include bone, bone marrow and neutrophil, and related mouse phenotype hematopoietic system.

Wikipedia:68 Transient erythroblastopenia of childhood (TEC) is a slowly developing anemia of early childhood... more...

Related Diseases for Transient Erythroblastopenia of Childhood

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Diseases related to Transient Erythroblastopenia of Childhood via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 68)
idRelated DiseaseScoreTop Affiliating Genes
1aplastic anemia30.0EPO, KITLG, RPS19
2chondrosarcoma10.4
3myxoid chondrosarcoma10.3
4hemolytic anemia10.3
5hepatitis10.3
6metabolic acidosis10.3
7congenital hypoplastic anemia10.3
8papilledema10.3
9transient hypogammaglobulinemia10.3
10asthma10.1
11behcet's disease10.1
12b cell deficiency10.1
13respiratory system disease10.1
14macular degeneration, age-related, 110.0
15hiv-110.0
16pulmonary hypertension, neonatal10.0
17obesity10.0
18anemia, sideroblastic, pyridoxine-refractory, autosomal recessive10.0
19major depressive disorder and accelerated response to antidepressant drug treatment10.0
20asthma 210.0
21microvascular complications of diabetes 510.0
22fanconi anemia, complementation group c10.0
23macular degeneration, age-related, 810.0
24multiple myeloma10.0
25pulmonary hypertension, primary, 210.0
26asthma 110.0
27pulmonary disease, chronic obstructive10.0
28pulmonary hypertension10.0
29cataract10.0
30neutropenia10.0
31foster-kennedy syndrome10.0
32diabetic cataract10.0
33ocular hypertension10.0
34allergic asthma10.0
35vascular skin disease10.0
36cork-handlers' disease10.0
37spiradenoma10.0
38autoimmune hemolytic anemia10.0
39candidiasis10.0
40carbohydrate metabolic disorder10.0
41corneal degeneration10.0
42corneal disease10.0
43eye degenerative disease10.0
44eye disease10.0
45facial nerve disease10.0
46globe disease10.0
47myeloma10.0
48neonatal diabetes mellitus10.0
49non-suppurative otitis media10.0
50obstructive lung disease10.0

Graphical network of the top 20 diseases related to Transient Erythroblastopenia of Childhood:



Diseases related to transient erythroblastopenia of childhood

Symptoms for Transient Erythroblastopenia of Childhood

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Symptoms by clinical synopsis from OMIM:

227050

Clinical features from OMIM:

227050

HPO human phenotypes related to Transient Erythroblastopenia of Childhood:

id Description Frequency HPO Source Accession
1 autosomal recessive inheritance HP:0000007
2 transient erythroblastopenia HP:0005510

Drugs & Therapeutics for Transient Erythroblastopenia of Childhood

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Transient Erythroblastopenia of Childhood

Genetic Tests for Transient Erythroblastopenia of Childhood

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Anatomical Context for Transient Erythroblastopenia of Childhood

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MalaCards organs/tissues related to Transient Erythroblastopenia of Childhood:

33
Bone, Bone marrow, Neutrophil, T cells

Animal Models for Transient Erythroblastopenia of Childhood or affiliated genes

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MGI Mouse Phenotypes related to Transient Erythroblastopenia of Childhood:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.1EPO, KITLG, RPS19, TEC

Publications for Transient Erythroblastopenia of Childhood

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Articles related to Transient Erythroblastopenia of Childhood:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Transient erythroblastopenia of childhood is an underdiagnosed and self-limiting disease. (24635829)
2014
2
Concomitant transient erythroblastopenia of childhood with neonatal hepatitis. (22335327)
2012
3
Ectopic atrial tachycardia in an infant with transient erythroblastopenia of childhood. (21730806)
2011
4
Transient erythroblastopenia of childhood in siblings: case report and review of the literature. (17805047)
2007
5
Classic transient erythroblastopenia of childhood with human parvovirus B19 genome detection in the blood and bone marrow. (15956889)
2005
6
Transient erythroblastopenia of childhood: prospective study of 10 patients with special reference to viral infections. (11972099)
2002
7
Case of transient erythroblastopenia of childhood with transient hypogammaglobulinemia. (10804733)
2000
8
Transient erythroblastopenia of childhood associated with transient neurologic deficit: report of a case and review of the literature. (9633983)
1998
9
Bone marrow biopsy findings in childhood anemia: prevalence of transient erythroblastopenia of childhood. (9674545)
1998
10
Transient erythroblastopenia of childhood associated with human herpesvirus type 6, variant B. (9260752)
1997
11
Breath-holding spells in a patient with transient erythroblastopenia of childhood. (9108866)
1997
12
Transient erythroblastopenia of childhood (TEC) presenting as leukoerythroblastic anemia. (9149751)
1997
13
Glycosylated haemoglobin and transient erythroblastopenia of childhood. (8551925)
1996
14
Polymerase chain reaction amplification of archival material for parvovirus B19 in children with transient erythroblastopenia of childhood. (9025846)
1996
15
Transient erythroblastopenia of childhood in infants < 6 months of age. (8037344)
1994
16
Transient erythroblastopenia of childhood presenting with shock and metabolic acidosis. (7845854)
1994
17
Transient erythroblastopenia of childhood. Prospective study of fifty patients. (7978049)
1994
18
Transient erythroblastopenia of childhood presenting with echovirus 11 infection. (8518530)
1993
19
Transient erythroblastopenia of childhood. Evidence for cell-mediated suppression of erythropoiesis. (8214360)
1993
20
Parvovirus B19 and transient erythroblastopenia of childhood. (8518188)
1993
21
Age dependency of red blood cell deformability and density: studies in transient erythroblastopenia of childhood. (8435319)
1993
22
Transient erythroblastopenia of childhood in Sweden: incidence and findings at the time of diagnosis. (8338993)
1993
23
Human parvovirus infection and transient erythroblastopenia of childhood. (1327065)
1992
24
Immature lymphocytes in transient erythroblastopenia of childhood. (1907620)
1991
25
Increase of CALLA-positive stimulated lymphoid cells in transient erythroblastopenia of childhood. (2140775)
1990
26
Transient erythroblastopenia of childhood with CD10, TdT, and cytoplasmic mu lymphocyte positivity in bone marrow. (2146287)
1990
27
AMP deaminase as a cell-age marker in transient erythroblastopenia of childhood and its role in the adenylate economy of erythrocytes. (2804355)
1989
28
Transient erythroblastopenia of childhood: implications for nurse practitioners. (2754596)
1989
29
Transient erythroblastopenia of childhood. A review of 26 cases and reassessment of indications for bone marrow aspiration. (2718996)
1989
30
Transient erythroblastopenia of childhood due to human parvovirus B19 infection. (2553096)
1989
31
Reduced neutrophil counts in children with transient erythroblastopenia of childhood. (2809908)
1989
32
Seasonal clustering of transient erythroblastopenia of childhood. (2829620)
1988
33
Transient erythroblastopenia of childhood. (18750483)
1988
34
Transient neurological disorder associated with transient erythroblastopenia of childhood. (3592128)
1987
35
Transient erythroblastopenia of childhood not associated with human parvovirus infection. (2869252)
1986
36
Transient erythroblastopenia of childhood presenting with papilledema. (3698450)
1986
37
Age-related red cell enzymes in children with transient erythroblastopenia of childhood and with hemolytic anemia. (2982125)
1985
38
T-cell mediated inhibition of erythropoiesis in transient erythroblastopenia of childhood. (3871630)
1985
39
Variable in vitro erythropoiesis in patients with transient erythroblastopenia of childhood. (4013369)
1985
40
Transient erythroblastopenia of childhood. A review of 22 cases. (6593224)
1984
41
Transient erythroblastopenia of childhood: varied pathogenesis. (6846328)
1983
42
Transient erythroblastopenia of childhood. Review of 17 cases, including a pair of identical twins. (7293995)
1981
43
Fetal-like erythropoiesis during recovery from transient erythroblastopenia of childhood (TEC). (7254949)
1981
44
Transient erythroblastopenia of childhood. (7271473)
1981
45
Transient erythroblastopenia of childhood presenting with reticulocytosis and erythroid hyperplasia in the bone marrow. (7254979)
1981
46
Nursing care study: transient erythroblastopenia of childhood. (6907956)
1981
47
Absence of inhibitory cells from patients with aplastic anemia or transient erythroblastopenia of childhood on the in vitro growth of erythroid colonies. (6968143)
1980
48
Immune suppression of erythropoiesis in transient erythroblastopenia of childhood. (465738)
1979
49
Idiopathic transient erythroblastopenia of childhood. (546244)
1979
50
Differentiation of transient erythroblastopenia of childhood from congenital hypoplastic anemia. (131849)
1976

Variations for Transient Erythroblastopenia of Childhood

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Expression for genes affiliated with Transient Erythroblastopenia of Childhood

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Search GEO for disease gene expression data for Transient Erythroblastopenia of Childhood.

Pathways for genes affiliated with Transient Erythroblastopenia of Childhood

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GO Terms for genes affiliated with Transient Erythroblastopenia of Childhood

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Biological processes related to Transient Erythroblastopenia of Childhood according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1erythrocyte differentiationGO:00302189.3EPO, RPS19
2positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.2KITLG, TEC
3positive regulation of DNA replicationGO:00457409.1EPO, KITLG
4positive regulation of Ras protein signal transductionGO:00465799.0EPO, KITLG

Sources for Transient Erythroblastopenia of Childhood

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet