TEC
MCID: TRN030
MIFTS: 34

Transient Erythroblastopenia of Childhood (TEC) malady

Categories: Rare diseases, Immune diseases, Blood diseases, Genetic diseases

Aliases & Classifications for Transient Erythroblastopenia of Childhood

Aliases & Descriptions for Transient Erythroblastopenia of Childhood:

Name: Transient Erythroblastopenia of Childhood 54 50 56 13
Transient Acquired Pure Red Cell Aplasia 56 69
Erythroblastopenia, Transient 50 52
Familial Transient Erythroblastopenia of Childhood 50
Tec 50

Characteristics:

HPO:

32
transient erythroblastopenia of childhood:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 54 227050
Orphanet 56 ORPHA98871
MESH via Orphanet 43 C536980
ICD10 via Orphanet 34 D60.1
UMLS via Orphanet 70 C0238478
ICD10 33 D60.1

Summaries for Transient Erythroblastopenia of Childhood

OMIM : 54 Transient erythroblastopenia of childhood is a pure red cell aplasia that occurs in a previously healthy child, most... (227050) more...

MalaCards based summary : Transient Erythroblastopenia of Childhood, also known as transient acquired pure red cell aplasia, is related to chondrosarcoma and myxoid chondrosarcoma, and has symptoms including transient erythroblastopenia An important gene associated with Transient Erythroblastopenia of Childhood is TEC (Tec Protein Tyrosine Kinase), and among its related pathways/superpathways are Tyrosine Kinases / Adaptors and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include bone, bone marrow and t cells, and related phenotype is limbs/digits/tail.

Wikipedia : 71 Transient erythroblastopenia of childhood (TEC) is a slowly developing anemia of early childhood... more...

Related Diseases for Transient Erythroblastopenia of Childhood

Graphical network of the top 20 diseases related to Transient Erythroblastopenia of Childhood:



Diseases related to Transient Erythroblastopenia of Childhood

Symptoms & Phenotypes for Transient Erythroblastopenia of Childhood

Symptoms by clinical synopsis from OMIM:

227050

Clinical features from OMIM:

227050

Human phenotypes related to Transient Erythroblastopenia of Childhood:

32
id Description HPO Frequency HPO Source Accession
1 transient erythroblastopenia 32 HP:0005510

MGI Mouse Phenotypes related to Transient Erythroblastopenia of Childhood:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 limbs/digits/tail MP:0005371 8.8 EPO KITLG RPS19

Drugs & Therapeutics for Transient Erythroblastopenia of Childhood

Search Clinical Trials , NIH Clinical Center for Transient Erythroblastopenia of Childhood

Genetic Tests for Transient Erythroblastopenia of Childhood

Anatomical Context for Transient Erythroblastopenia of Childhood

MalaCards organs/tissues related to Transient Erythroblastopenia of Childhood:

39
Bone, Bone Marrow, T Cells, Neutrophil

Publications for Transient Erythroblastopenia of Childhood

Articles related to Transient Erythroblastopenia of Childhood:

(show top 50) (show all 53)
id Title Authors Year
1
Deformation of erythroblasts in transient erythroblastopenia of childhood caused by HHV-6. ( 28092892 )
2016
2
Transient erythroblastopenia of childhood is an underdiagnosed and self-limiting disease. ( 24635829 )
2014
3
Concomitant transient erythroblastopenia of childhood with neonatal hepatitis. ( 22335327 )
2012
4
Ectopic atrial tachycardia in an infant with transient erythroblastopenia of childhood. ( 21730806 )
2011
5
Transient erythroblastopenia of childhood in siblings: case report and review of the literature. ( 17805047 )
2007
6
Classic transient erythroblastopenia of childhood with human parvovirus B19 genome detection in the blood and bone marrow. ( 15956889 )
2005
7
Familial transient erythroblastopenia of childhood is associated with the chromosome 19q13.2 region but not caused by mutations in coding sequences of the ribosomal protein S19 (RPS19) gene. ( 12358933 )
2002
8
Transient erythroblastopenia of childhood: prospective study of 10 patients with special reference to viral infections. ( 11972099 )
2002
9
Case of transient erythroblastopenia of childhood with transient hypogammaglobulinemia. ( 10804733 )
2000
10
Bone marrow biopsy findings in childhood anemia: prevalence of transient erythroblastopenia of childhood. ( 9674545 )
1998
11
Transient erythroblastopenia of childhood associated with transient neurologic deficit: report of a case and review of the literature. ( 9633983 )
1998
12
Breath-holding spells in a patient with transient erythroblastopenia of childhood. ( 9108866 )
1997
13
Transient erythroblastopenia of childhood (TEC) presenting as leukoerythroblastic anemia. ( 9149751 )
1997
14
Transient erythroblastopenia of childhood associated with human herpesvirus type 6, variant B. ( 9260752 )
1997
15
Glycosylated haemoglobin and transient erythroblastopenia of childhood. ( 8551925 )
1996
16
Polymerase chain reaction amplification of archival material for parvovirus B19 in children with transient erythroblastopenia of childhood. ( 9025846 )
1996
17
Transient erythroblastopenia of childhood. Prospective study of fifty patients. ( 7978049 )
1994
18
Transient erythroblastopenia of childhood in infants < 6 months of age. ( 8037344 )
1994
19
Transient erythroblastopenia of childhood presenting with shock and metabolic acidosis. ( 7845854 )
1994
20
Transient erythroblastopenia of childhood presenting with echovirus 11 infection. ( 8518530 )
1993
21
Transient erythroblastopenia of childhood. Evidence for cell-mediated suppression of erythropoiesis. ( 8214360 )
1993
22
Age dependency of red blood cell deformability and density: studies in transient erythroblastopenia of childhood. ( 8435319 )
1993
23
Parvovirus B19 and transient erythroblastopenia of childhood. ( 8518188 )
1993
24
Transient erythroblastopenia of childhood in Sweden: incidence and findings at the time of diagnosis. ( 8338993 )
1993
25
Transient erythroblastopenia of childhood with megakaryocytopenia associated with human parvovirus B19 infection. ( 1536802 )
1992
26
Human parvovirus infection and transient erythroblastopenia of childhood. ( 1327065 )
1992
27
Immature lymphocytes in transient erythroblastopenia of childhood. ( 1907620 )
1991
28
Increase of CALLA-positive stimulated lymphoid cells in transient erythroblastopenia of childhood. ( 2140775 )
1990
29
Transient erythroblastopenia of childhood with CD10, TdT, and cytoplasmic mu lymphocyte positivity in bone marrow. ( 2146287 )
1990
30
Transient erythroblastopenia of childhood due to human parvovirus B19 infection. ( 2553096 )
1989
31
Reduced neutrophil counts in children with transient erythroblastopenia of childhood. ( 2809908 )
1989
32
Transient erythroblastopenia of childhood. A review of 26 cases and reassessment of indications for bone marrow aspiration. ( 2718996 )
1989
33
AMP deaminase as a cell-age marker in transient erythroblastopenia of childhood and its role in the adenylate economy of erythrocytes. ( 2804355 )
1989
34
Transient erythroblastopenia of childhood: implications for nurse practitioners. ( 2754596 )
1989
35
Transient erythroblastopenia of childhood. ( 18750483 )
1988
36
Seasonal clustering of transient erythroblastopenia of childhood. ( 2829620 )
1988
37
Transient neurological disorder associated with transient erythroblastopenia of childhood. ( 3592128 )
1987
38
Transient erythroblastopenia of childhood not associated with human parvovirus infection. ( 2869252 )
1986
39
Transient erythroblastopenia of childhood presenting with papilledema. ( 3698450 )
1986
40
Age-related red cell enzymes in children with transient erythroblastopenia of childhood and with hemolytic anemia. ( 2982125 )
1985
41
Variable in vitro erythropoiesis in patients with transient erythroblastopenia of childhood. ( 4013369 )
1985
42
T-cell mediated inhibition of erythropoiesis in transient erythroblastopenia of childhood. ( 3871630 )
1985
43
Transient erythroblastopenia of childhood. A review of 22 cases. ( 6593224 )
1984
44
Transient erythroblastopenia of childhood: varied pathogenesis. ( 6846328 )
1983
45
Nursing care study: transient erythroblastopenia of childhood. ( 6907956 )
1981
46
Transient erythroblastopenia of childhood. Review of 17 cases, including a pair of identical twins. ( 7293995 )
1981
47
Fetal-like erythropoiesis during recovery from transient erythroblastopenia of childhood (TEC). ( 7254949 )
1981
48
Transient erythroblastopenia of childhood. ( 7271473 )
1981
49
Transient erythroblastopenia of childhood presenting with reticulocytosis and erythroid hyperplasia in the bone marrow. ( 7254979 )
1981
50
Absence of inhibitory cells from patients with aplastic anemia or transient erythroblastopenia of childhood on the in vitro growth of erythroid colonies. ( 6968143 )
1980

Variations for Transient Erythroblastopenia of Childhood

Expression for Transient Erythroblastopenia of Childhood

Search GEO for disease gene expression data for Transient Erythroblastopenia of Childhood.

Pathways for Transient Erythroblastopenia of Childhood

GO Terms for Transient Erythroblastopenia of Childhood

Biological processes related to Transient Erythroblastopenia of Childhood according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.26 KITLG TEC
2 erythrocyte differentiation GO:0030218 9.16 EPO RPS19
3 positive regulation of DNA replication GO:0045740 8.96 EPO KITLG
4 positive regulation of Ras protein signal transduction GO:0046579 8.62 EPO KITLG

Sources for Transient Erythroblastopenia of Childhood

3 CDC
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10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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