MCID: TRN030
MIFTS: 37

Transient Erythroblastopenia of Childhood malady

Categories: Genetic diseases, Rare diseases, Immune diseases, Blood diseases

Aliases & Classifications for Transient Erythroblastopenia of Childhood

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Sources:
49OMIM, 11diseasecard, 45NIH Rare Diseases, 51Orphanet, 47Novoseek, 65UMLS, 66UMLS via Orphanet, 28ICD10 via Orphanet, 37MESH via Orphanet, 27ICD10, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Transient Erythroblastopenia of Childhood:

Name: Transient Erythroblastopenia of Childhood 49 11 45 51
Transient Acquired Pure Red Cell Aplasia 51 65
Erythroblastopenia, Transient 45 47
 
Familial Transient Erythroblastopenia of Childhood 45
Tec 45

Characteristics:

HPO:

61
transient erythroblastopenia of childhood:
Inheritance: autosomal recessive inheritance


Classifications:



External Ids:

OMIM49 227050
Orphanet51 98871
UMLS via Orphanet66 C0238478
ICD10 via Orphanet28 D60.1
MESH via Orphanet37 C536980
ICD1027 D60.1
UMLS65 C0451688

Summaries for Transient Erythroblastopenia of Childhood

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OMIM:49 Transient erythroblastopenia of childhood is a pure red cell aplasia that occurs in a previously healthy child, most... (227050) more...

MalaCards based summary: Transient Erythroblastopenia of Childhood, also known as transient acquired pure red cell aplasia, is related to agammaglobulinemia and cervicitis, and has symptoms including transient erythroblastopenia An important gene associated with Transient Erythroblastopenia of Childhood is TEC (Tec Protein Tyrosine Kinase), and among its related pathways are Osteoclast differentiation and G12-G13 in Cellular Signaling. Affiliated tissues include lung, prostate and neutrophil.

Wikipedia:68 Transient erythroblastopenia of childhood (TEC) is a slowly developing anemia of early childhood... more...

Related Diseases for Transient Erythroblastopenia of Childhood

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Graphical network of the top 20 diseases related to Transient Erythroblastopenia of Childhood:



Diseases related to transient erythroblastopenia of childhood

Symptoms for Transient Erythroblastopenia of Childhood

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Symptoms by clinical synopsis from OMIM:

227050

Clinical features from OMIM:

227050

HPO human phenotypes related to Transient Erythroblastopenia of Childhood:

id Description Frequency HPO Source Accession
1 transient erythroblastopenia HP:0005510

Drugs & Therapeutics for Transient Erythroblastopenia of Childhood

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Transient Erythroblastopenia of Childhood

Genetic Tests for Transient Erythroblastopenia of Childhood

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Anatomical Context for Transient Erythroblastopenia of Childhood

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MalaCards organs/tissues related to Transient Erythroblastopenia of Childhood:

33
Lung, Prostate, Neutrophil, Pituitary, Breast, Placenta, Monocytes

Animal Models for Transient Erythroblastopenia of Childhood or affiliated genes

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Publications for Transient Erythroblastopenia of Childhood

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Articles related to Transient Erythroblastopenia of Childhood:

(show top 50)    (show all 52)
idTitleAuthorsYear
1
Intraneuronal accumulation of misfolded tau protein induces overexpression of Hsp27 in activated astrocytes. (25772164)
2015
2
Ear gel to treat otitis externa in dogs. (26475907)
2015
3
282: SIGNIFICANCE OF LACTIC ACIDOSIS AND GLUCOSE LEVELS IN DIABETIC KETOACIDOSIS. (26569943)
2015
4
Clinical evaluation of chinese patients with primary distal renal tubular acidosis. (25832932)
2015
5
The impact of concomitant allergic rhinitis on asthma control: a cross-sectional nationwide survey in China. (24000784)
2014
6
Salivary alkaline phosphatase and calcium in caries-active type II diabetes mellitus patients: An in vivo study. (25395756)
2014
7
Efficacy and safety of open-label ixekizumab treatment in Japanese patients with moderate-to-severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis. (25355284)
2014
8
FDG PET/CT imaging in prostate adenocarcinoma presenting as isolated brain metastases of unknown origin. (25052407)
2014
9
Quantitative proteomics analysis of varicose veins: identification of a set of differentially expressed proteins related to ATP generation and utilization. (24183353)
2013
10
Down-regulation of MTA1 protein leads to the inhibition of migration, invasion, and angiogenesis of non-small-cell lung cancer cell line. (23343746)
2013
11
Rethinking nephrolithiasis in military aviation. (22462375)
2012
12
Comparison of two shampoos as sole treatment for canine bacterial overgrowth syndrome. (22678617)
2012
13
PAMUS: placenta accreta management across the United States. (21843108)
2012
14
2012 ISBRA (International Society for Biomedical Research on Alcoholism) World Congress. September 8-12, 2012. Sapporo, Japan. (22946536)
2012
15
Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients. (22270930)
2012
16
In silico study on the substrate binding manner in human myo-inositol monophosphatase 2. (21213002)
2011
17
The fibroblast growth factor receptor-4 Arg388 allele is associated with gastric cancer progression. (20844967)
2010
18
Absence of ligand-independent transcriptional activation of the estrogen receptor via the estrogen response element in pituitary lactotrophs in primary culture. (19883758)
2010
19
Local protease signaling contributes to neural tube closure in the mouse embryo. (20152175)
2010
20
Human pituitary contains dual cathepsin L and prohormone convertase processing pathway components involved in converting POMC into the peptide hormones ACTH, alpha-MSH, and beta-endorphin. (19343278)
2009
21
Crystalluric and tubular epithelial parameters during the onset of intratubular nephrocalcinosis: illustration of the 'fixed particle' theory in vivo. (19717825)
2009
22
Association of the gene polymorphisms IFN-gamma +874, IL-13 -1055 and IL-4 -590 with patterns of reinfection with Schistosoma mansoni. (19190772)
2009
23
Enhancement of immunotherapeutic effects of HPV16E7 on cervical cancer by fusion with CTLA4 extracellular region. (19107404)
2008
24
Polyamines are required for expression of Toll-like receptor 2 modulating intestinal epithelial barrier integrity. (17600044)
2007
25
NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility. (17229887)
2007
26
Correlation of polymorphisms of UDP-glucuronosyltransferase 1A7 gene to genetic susceptibility of lung cancer]. (16159430)
2005
27
Modification of motor cortical excitability by an acetylcholinesterase inhibitor. (15991031)
2005
28
Hypophosphataemic osteomalacia due to de Toni-Debre-Fanconi syndrome in a 19-year old girl. (16613828)
2005
29
The importance of diagnostic work-up in the management of candidal vulvovaginitis. A prospective study. (15266763)
2004
30
Xanthogranulomatous cholecystitis: 15 years' experience. (14961199)
2004
31
Leukocyte CD11b and CD62l expression in response to interstitial inflammation in CAPD patients. (15104334)
2004
32
Length-dependent structure formation in Friedreich ataxia (GAA)n*(TTC)n repeats at neutral pH. (14978261)
2004
33
Dapsone hypersensitivity or viral exanthem? (15339092)
2004
34
From acute to chronic pancreatitis: the role of mutations in the pancreatic secretory trypsin inhibitor gene. (12629264)
2003
35
Regulation of Vav localization in membrane rafts by adaptor molecules Grb2 and BLNK. (12818159)
2003
36
Stachybotrys chartarum: cause of human disease or media darling? (12964721)
2003
37
Preserving the superior rectal artery in laparoscopic [correction of laparoscopis] anterior resection for complete rectal prolapse. (12587465)
2002
38
Cell-adhesion molecules and fibroblast growth factor signalling in Hirschsprung's disease. (11409166)
2001
39
Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils. (11449371)
2001
40
NCX4016 (NO-aspirin) inhibits thromboxane biosynthesis and tissue factor expression and activity in human monocytes. (11433179)
2001
41
Pathological study of the pleomorphic carcinoma of the lung]. (11866944)
2000
42
Prostatic adenocarcinoma diagnosed by prostate-specific antigen analysis of pleural fluid. (9644796)
1998
43
Qualitative platelet 12-lipoxygenase abnormality in a patient with essential thrombocythemia. (9157584)
1997
44
Acute adrenal insufficiency. (8325289)
1993
45
A red cell band 3 variant with altered stilbene disulphonate binding is associated with the Diego (Dia) blood group antigen. (1471983)
1992
46
Endothelin-1--marker or mediator of vascular disease? (2268791)
1990
47
Giant axonal neuropathy (GAN): an immunohistochemical and ultrastructural study report of a Latin American case. (1703388)
1990
48
Gallium uptake in Erdheim-Chester disease. (7140108)
1982
49
Mooren's ulcer. Treatment by conjunctival excision. (1106759)
1975
50
Male pseudohermaphroditism. (4616022)
1974

Variations for Transient Erythroblastopenia of Childhood

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Expression for genes affiliated with Transient Erythroblastopenia of Childhood

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Search GEO for disease gene expression data for Transient Erythroblastopenia of Childhood.

Pathways for genes affiliated with Transient Erythroblastopenia of Childhood

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GO Terms for genes affiliated with Transient Erythroblastopenia of Childhood

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Biological processes related to Transient Erythroblastopenia of Childhood according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.4KITLG, TEC
2positive regulation of Ras protein signal transductionGO:00465799.2EPO, KITLG
3erythrocyte differentiationGO:00302189.0EPO, RPS19
4positive regulation of DNA replicationGO:00457408.8EPO, KITLG

Sources for Transient Erythroblastopenia of Childhood

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet