MCID: TRN030
MIFTS: 35

Transient Erythroblastopenia of Childhood malady

Categories: Genetic diseases, Rare diseases, Immune diseases, Blood diseases

Aliases & Classifications for Transient Erythroblastopenia of Childhood

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Sources:
50OMIM, 46NIH Rare Diseases, 52Orphanet, 12diseasecard, 48Novoseek, 67UMLS via Orphanet, 29ICD10 via Orphanet, 38MESH via Orphanet, 28ICD10, 62The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Transient Erythroblastopenia of Childhood:

Name: Transient Erythroblastopenia of Childhood 50 46 52 12
Erythroblastopenia, Transient 46 48
Familial Transient Erythroblastopenia of Childhood 46
 
Transient Acquired Pure Red Cell Aplasia 52
Tec 46

Characteristics:

HPO:

62
transient erythroblastopenia of childhood:
Inheritance: autosomal recessive inheritance


Classifications:



External Ids:

OMIM50 227050
Orphanet52 ORPHA98871
UMLS via Orphanet67 C0238478
ICD10 via Orphanet29 D60.1
MESH via Orphanet38 C536980
ICD1028 D60.1

Summaries for Transient Erythroblastopenia of Childhood

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OMIM:50 Transient erythroblastopenia of childhood is a pure red cell aplasia that occurs in a previously healthy child, most... (227050) more...

MalaCards based summary: Transient Erythroblastopenia of Childhood, also known as erythroblastopenia, transient, is related to chondrosarcoma and myxoid chondrosarcoma, and has symptoms including transient erythroblastopenia An important gene associated with Transient Erythroblastopenia of Childhood is TEC (Tec Protein Tyrosine Kinase), and among its related pathways are Tyrosine Kinases / Adaptors and Development EPO-induced Jak-STAT pathway. Affiliated tissues include bone marrow, bone and neutrophil.

Wikipedia:69 Transient erythroblastopenia of childhood (TEC) is a slowly developing anemia of early childhood... more...

Related Diseases for Transient Erythroblastopenia of Childhood

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Graphical network of the top 20 diseases related to Transient Erythroblastopenia of Childhood:



Diseases related to transient erythroblastopenia of childhood

Symptoms for Transient Erythroblastopenia of Childhood

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Symptoms by clinical synopsis from OMIM:

227050

Clinical features from OMIM:

227050

HPO human phenotypes related to Transient Erythroblastopenia of Childhood:

id Description Frequency HPO Source Accession
1 transient erythroblastopenia HP:0005510

Drugs & Therapeutics for Transient Erythroblastopenia of Childhood

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Transient Erythroblastopenia of Childhood

Genetic Tests for Transient Erythroblastopenia of Childhood

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Anatomical Context for Transient Erythroblastopenia of Childhood

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MalaCards organs/tissues related to Transient Erythroblastopenia of Childhood:

34
Bone marrow, Bone, Neutrophil, T cells

Animal Models for Transient Erythroblastopenia of Childhood or affiliated genes

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Publications for Transient Erythroblastopenia of Childhood

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Articles related to Transient Erythroblastopenia of Childhood:

(show top 50)    (show all 52)
idTitleAuthorsYear
1
Transient erythroblastopenia of childhood is an underdiagnosed and self-limiting disease. (24635829)
2014
2
Concomitant transient erythroblastopenia of childhood with neonatal hepatitis. (22335327)
2012
3
Ectopic atrial tachycardia in an infant with transient erythroblastopenia of childhood. (21730806)
2011
4
Transient erythroblastopenia of childhood in siblings: case report and review of the literature. (17805047)
2007
5
Classic transient erythroblastopenia of childhood with human parvovirus B19 genome detection in the blood and bone marrow. (15956889)
2005
6
Transient erythroblastopenia of childhood: prospective study of 10 patients with special reference to viral infections. (11972099)
2002
7
Case of transient erythroblastopenia of childhood with transient hypogammaglobulinemia. (10804733)
2000
8
Bone marrow biopsy findings in childhood anemia: prevalence of transient erythroblastopenia of childhood. (9674545)
1998
9
Transient erythroblastopenia of childhood associated with transient neurologic deficit: report of a case and review of the literature. (9633983)
1998
10
Breath-holding spells in a patient with transient erythroblastopenia of childhood. (9108866)
1997
11
Transient erythroblastopenia of childhood (TEC) presenting as leukoerythroblastic anemia. (9149751)
1997
12
Transient erythroblastopenia of childhood associated with human herpesvirus type 6, variant B. (9260752)
1997
13
Glycosylated haemoglobin and transient erythroblastopenia of childhood. (8551925)
1996
14
Polymerase chain reaction amplification of archival material for parvovirus B19 in children with transient erythroblastopenia of childhood. (9025846)
1996
15
Transient erythroblastopenia of childhood presenting with shock and metabolic acidosis. (7845854)
1994
16
Transient erythroblastopenia of childhood. Prospective study of fifty patients. (7978049)
1994
17
Transient erythroblastopenia of childhood in infants < 6 months of age. (8037344)
1994
18
Transient erythroblastopenia of childhood presenting with echovirus 11 infection. (8518530)
1993
19
Transient erythroblastopenia of childhood. Evidence for cell-mediated suppression of erythropoiesis. (8214360)
1993
20
Age dependency of red blood cell deformability and density: studies in transient erythroblastopenia of childhood. (8435319)
1993
21
Parvovirus B19 and transient erythroblastopenia of childhood. (8518188)
1993
22
Transient erythroblastopenia of childhood in Sweden: incidence and findings at the time of diagnosis. (8338993)
1993
23
Human parvovirus infection and transient erythroblastopenia of childhood. (1327065)
1992
24
Transient erythroblastopenia of childhood with megakaryocytopenia associated with human parvovirus B19 infection. (1536802)
1992
25
Immature lymphocytes in transient erythroblastopenia of childhood. (1907620)
1991
26
Increase of CALLA-positive stimulated lymphoid cells in transient erythroblastopenia of childhood. (2140775)
1990
27
Transient erythroblastopenia of childhood with CD10, TdT, and cytoplasmic mu lymphocyte positivity in bone marrow. (2146287)
1990
28
AMP deaminase as a cell-age marker in transient erythroblastopenia of childhood and its role in the adenylate economy of erythrocytes. (2804355)
1989
29
Transient erythroblastopenia of childhood: implications for nurse practitioners. (2754596)
1989
30
Transient erythroblastopenia of childhood. A review of 26 cases and reassessment of indications for bone marrow aspiration. (2718996)
1989
31
Transient erythroblastopenia of childhood due to human parvovirus B19 infection. (2553096)
1989
32
Seasonal clustering of transient erythroblastopenia of childhood. (2829620)
1988
33
Transient erythroblastopenia of childhood. (18750483)
1988
34
Transient neurological disorder associated with transient erythroblastopenia of childhood. (3592128)
1987
35
Transient erythroblastopenia of childhood not associated with human parvovirus infection. (2869252)
1986
36
Transient erythroblastopenia of childhood presenting with papilledema. (3698450)
1986
37
Variable in vitro erythropoiesis in patients with transient erythroblastopenia of childhood. (4013369)
1985
38
Age-related red cell enzymes in children with transient erythroblastopenia of childhood and with hemolytic anemia. (2982125)
1985
39
T-cell mediated inhibition of erythropoiesis in transient erythroblastopenia of childhood. (3871630)
1985
40
Transient erythroblastopenia of childhood. A review of 22 cases. (6593224)
1984
41
Transient erythroblastopenia of childhood: varied pathogenesis. (6846328)
1983
42
Transient erythroblastopenia of childhood. Review of 17 cases, including a pair of identical twins. (7293995)
1981
43
Fetal-like erythropoiesis during recovery from transient erythroblastopenia of childhood (TEC). (7254949)
1981
44
Transient erythroblastopenia of childhood. (7271473)
1981
45
Transient erythroblastopenia of childhood presenting with reticulocytosis and erythroid hyperplasia in the bone marrow. (7254979)
1981
46
Nursing care study: transient erythroblastopenia of childhood. (6907956)
1981
47
Absence of inhibitory cells from patients with aplastic anemia or transient erythroblastopenia of childhood on the in vitro growth of erythroid colonies. (6968143)
1980
48
Immune suppression of erythropoiesis in transient erythroblastopenia of childhood. (465738)
1979
49
Idiopathic transient erythroblastopenia of childhood. (546244)
1979
50
Differentiation of transient erythroblastopenia of childhood from congenital hypoplastic anemia. (131849)
1976

Variations for Transient Erythroblastopenia of Childhood

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Expression for genes affiliated with Transient Erythroblastopenia of Childhood

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Search GEO for disease gene expression data for Transient Erythroblastopenia of Childhood.

Pathways for genes affiliated with Transient Erythroblastopenia of Childhood

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GO Terms for genes affiliated with Transient Erythroblastopenia of Childhood

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Biological processes related to Transient Erythroblastopenia of Childhood according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.5KITLG, TEC
2positive regulation of Ras protein signal transductionGO:00465799.0EPO, KITLG
3erythrocyte differentiationGO:00302189.0EPO, RPS19
4positive regulation of DNA replicationGO:00457408.8EPO, KITLG

Sources for Transient Erythroblastopenia of Childhood

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet