TGA
MCID: TRN012
MIFTS: 42

Transient Global Amnesia (TGA) malady

Neuronal diseases category

Summaries for Transient Global Amnesia

About this section
Sources:
8Disease Ontology, 42NIH Rare Diseases, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
NIH Rare Diseases:42 Transient global amnesia (tga) is a condition characterized by sudden onset of memory loss and confusion. affected individuals are often disoriented in regard to time and place but usually remember their identity and can recognize family members. tga typically lasts for hours, although its duration may range from minutes to days. individuals usually have only one episode of tga during their life, although the condition reoccurs in about 5-25 percent of people. affected individuals do not experience symptoms after the episode of amnesia has resolved. last updated: 6/2/2009

MalaCards: Transient Global Amnesia, also known as amnesia, transient global, is related to migraine and ischemia. An important gene associated with Transient Global Amnesia is CRLF1 (cytokine receptor-like factor 1). The compounds cyclothiazide and chlorpromazine have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe, brain and cortex.

Disease Ontology:8 An amnestic disorder that is characterized by temporary but almost total disruption of short-term memory with a range of problems accessing older memories.

Wikipedia:63 Transient global amnesia (TGA) is a neurological disorder whose key defining characteristic is a... more...

Aliases & Classifications for Transient Global Amnesia

About this section
Sources:
8Disease Ontology, 42NIH Rare Diseases, 60UMLS, 56SNOMED-CT, 39NCIt, 27ICD9CM, 34MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

transient global amnesia 8 42
amnesia, transient global 60
tga 42


External Ids:

Disease Ontology8 DOID:13027
NCIt39 C85198
ICD9CM27 437.7
MeSH34 D020236
ICD1025 G45.4

Related Diseases for Transient Global Amnesia

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Transient Global Amnesia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 64)
idRelated DiseaseScoreTop Affiliating Genes
1migraine31.3PDE5A, APOH
2ischemia30.9PDE5A, BDNF
3cerebritis10.9
4meningioma10.6
5retrograde amnesia10.4
6encephalitis10.4
7stroke, ischemic10.4
8neuronitis10.4
9acute myocardial infarction10.4
10aphasia10.4
11herpes simplex10.4
12hydrocephalus10.4
13myocardial infarction10.4
14thrombocytopenia10.4
15transient cerebral ischemia10.4
16transposition of the great arteries, dextro-looped 210.2
17transposition of the great arteries, dextro-looped 110.2
18transposition of great arteries, dextro-looped 310.2
19arteriovenous fistula10.2
20sneddon syndrome10.2
21parametritis10.2
22antiphospholipid syndrome10.2
23patent foramen ovale10.2
24temporal lobe epilepsy10.2
25dissociative amnesia10.2
26arachnoiditis10.2
27hyperhomocysteinemia10.2
28dissecting aortic aneurysm10.2
29viral encephalitis10.2
30cortical blindness10.2
31anterograde amnesia10.2
32carotid artery occlusion10.2
33obstructive hydrocephalus10.2
34adenoma10.2
35aortic aneurysm10.2
36dementia10.2
37diabetes mellitus10.2
38hypertension10.2
39pituitary adenoma10.2
40scleroderma10.2
41congenitally corrected transposition of the great arteries10.2
42transposition of the great arteries10.2
43situs inversus10.1
44thalassemia10.1
45hemophilia10.1
46labyrinthitis10.0CRLF1
47sjogren's syndrome10.0APOH
48breast cancer10.0KLF6, FUT3
49pulmonary embolism10.0APOH
50ischemic optic neuropathy10.0PDE5A

Graphical network of the top 20 diseases related to Transient Global Amnesia:



Diseases related to transient global amnesia

Clinical Features for Transient Global Amnesia

About this section

Drugs & Therapeutics for Transient Global Amnesia

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Transient Global Amnesia

Drug clinical trials:

Search ClinicalTrials for Transient Global Amnesia

Search NIH Clinical Center for Transient Global Amnesia

Search CenterWatch for Transient Global Amnesia

Genetic Tests for Transient Global Amnesia

About this section

Anatomical Context for Transient Global Amnesia

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Transient Global Amnesia:

32
Temporal lobe, Brain, Cortex, Heart, Testes, Prefrontal cortex, Thalamus, Caudate nucleus, Pituitary

Animal Models for Transient Global Amnesia or affiliated genes

About this section

Publications for Transient Global Amnesia

About this section
Sources:
50PubMed
See all sources

Articles related to Transient Global Amnesia:

(show top 50)    (show all 479)
idTitleAuthorsYear
1
Neuroimaging in transient global amnesia. (23315465)
2013
2
Mere exposure effect can be elicited in transient global amnesia. (24131047)
2013
3
Different Risk Factor Profiles between Transient Global Amnesia and Transient Ischemic Attack: A Large Case-Control Study. (24281363)
2013
4
Neurological picture. Transient global amnesia associated with bilateral restricted diffusion in the lateral hippocampus. (23385845)
2013
5
Lost memories can break your heart: a case report of transient global amnesia followed by takotsubo cardiomyopathy. (23771740)
2013
6
Transient global amnesia, cerebral veins, and the need to find the 'smoking gun'. (22821610)
2012
7
Transient global amnesia after prolonged and abnormal head posture. (21227571)
2011
8
Transient global amnesia as the presenting feature of heparin-induced thrombocytopenia. (20202039)
2010
9
Tadalafil-induced transient global amnesia. (20686164)
2010
10
Transient global amnesia: a genetic disorder? (20203515)
2010
11
Transient global amnesia associated with statin intake. (21686951)
2009
12
Optimal diffusion-weighted imaging protocol for lesion detection in transient global amnesia. (18451087)
2008
13
Selective affection of hippocampal CA-1 neurons in patients with transient global amnesia without long-term sequelae. (17003071)
2006
14
Transient global amnesia after intake of tadalafil, a PDE-5 inhibitor: a possible association? (15674402)
2005
15
Transient global amnesia secondary to herpes simplex viral encephalitis. (15671476)
2005
16
Transient global amnesia and migraine. (16324175)
2005
17
A puzzling case of transient global amnesia. (15302202)
2004
18
Sildenafil and transient global amnesia. (14598059)
2003
19
Transient Global Amnesia. Evidence against vascular ischemic etiology from diffusion weighted imaging. (12420091)
2002
20
Transient global amnesia (TGA) in an MEG study. (11545155)
2001
21
Clinical features, vascular risk factors, and prognosis for transient global amnesia in Chinese patients. (17895178)
1999
22
Diffusion-weighted MRI characterizes the ischemic lesion in transient global amnesia. (9748056)
1998
23
Transient global amnesia and migraine in young people. (9107472)
1997
24
Transient global amnesia and thalamic hemorrhage. (8930421)
1996
25
Long-term perceptual priming in transient global amnesia. (8790935)
1996
26
Transient global amnesia. (8299284)
1993
27
Technetium-99m HM-PAO single photon emission computed tomography imaging in transient global amnesia. (1580818)
1992
28
Scopolamine intoxication as a model of transient global amnesia. (2043366)
1991
29
Persistent memory impairment following transient global amnesia. (2286654)
1990
30
Transient global amnesia. (2199958)
1990
31
Ethmoidal meningioma revealed by transient global amnesia. (2737865)
1989
32
Observations during transient global amnesia. A behavioural and neuropsychological study of five cases. (2731023)
1989
33
Transient global amnesia and left frontal haemorrhage. (3174526)
1988
34
Transient global amnesia: a personal series of 60 cases. (3170164)
1988
35
Transient global amnesia: case-reports. (3170163)
1988
36
Transient global amnesia after mild head injury in childhood. (3381647)
1988
37
Transient global amnesia: complication of arterial DSA. (3082139)
1986
38
Transient global amnesia: a report of three cases and review of the literature. (3823949)
1986
39
Transient global amnesia following general anesthesia. (4003806)
1985
40
Transient global amnesia: diagnosis in the emergency department. (4005009)
1985
41
Transient global amnesia: a presentation of subarachnoid haemorrhage. (6520626)
1984
42
Transient global amnesia. (6516786)
1984
43
Transient global amnesia. Precipitating activities and other observations. (7125972)
1982
44
Transient global amnesia as an epileptic manifestation. (6169809)
1981
45
Transient global amnesia and temporary memory loss. (7393049)
1980
46
Transient global amnesia syndrome. (5109090)
1971
47
Transient global amnesia. (5347005)
1969
48
Transient global amnesia. (5706979)
1968
49
Cerebral infarction with transient global amnesia. (6062254)
1967
50
The transient global amnesia syndrome. (5953341)
1966

Genetic Variations for Transient Global Amnesia

About this section

Expression for genes affiliated with Transient Global Amnesia

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Transient Global Amnesia

Search GEO for disease gene expression data for Transient Global Amnesia.

Pathways for genes affiliated with Transient Global Amnesia

About this section

Compounds for genes affiliated with Transient Global Amnesia

About this section
Sources:
28IUPHAR, 44Novoseek, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 24HMDB
See all sources

Compounds related to Transient Global Amnesia according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1cyclothiazide28 44 1111.7BDNF, CA1
2chlorpromazine44 28 49 1112.4BDNF, APOH
3cocaine44 1110.1RABEP2, APOH, BDNF
4gold448.9APOH, PDE5A, BDNF
5indomethacin44 59 28 1111.7PDE5A, CA1, BDNF
6norepinephrine44 11 2410.7PDE5A, CA1, BDNF
7dopamine44 28 11 2411.5RABEP2, PDE5A, BDNF
8arginine448.4HNRNPC, CA1, PDE5A, APOH
9hydrogen44 249.4PDE5A, CA1, BDNF
10zinc44 249.2APOH, PDE5A, CA1, BDNF, KLF6
11estrogen448.0KLF6, BDNF, PDE5A, APOH, RABEP2

GO Terms for genes affiliated with Transient Global Amnesia

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Transient Global Amnesia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ureteric bud developmentGO:0016579.6CRLF1, BDNF

Products for genes affiliated with Transient Global Amnesia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Transient Global Amnesia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet