MCID: TRN012
MIFTS: 38

Transient Global Amnesia malady

Categories: Rare diseases, Neuronal diseases, Mental diseases

Aliases & Classifications for Transient Global Amnesia

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Aliases & Descriptions for Transient Global Amnesia:

Name: Transient Global Amnesia 11 46 13
Amnesia, Transient Global 37 66
 
Tga 46

Classifications:



External Ids:

Disease Ontology11 DOID:13027
ICD1028 G45.4
ICD9CM30 437.7
MeSH37 D020236
NCIt43 C85198

Summaries for Transient Global Amnesia

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NIH Rare Diseases:46 Transient global amnesia (tga) is a condition characterized by sudden onset of memory loss and confusion. affected people are often disoriented in regard to time and place, but usually remember their identity and can recognize family members. tga typically lasts for several hours, and rarely for up to 24 hours. while most people have only one episode of tga during their lifetime, 5-25% of people have a recurrence. the underlying cause of tga is unclear. there is no specific treatment for tga. it resolves on it's own, but memory for events during the episode may be lost. last updated: 2/3/2016

MalaCards based summary: Transient Global Amnesia, also known as amnesia, transient global, is related to transposition of the great arteries and transposition of the great arteries, dextro-looped 1, and has symptoms including amaurosis fugax An important gene associated with Transient Global Amnesia is PDE5A (Phosphodiesterase 5A), and among its related pathways are FOXM1 transcription factor network and cAMP signaling pathway. Affiliated tissues include temporal lobe, brain and heart.

Disease Ontology:11 An amnestic disorder that is characterized by temporary but almost total disruption of short-term memory with a range of problems accessing older memories.

Wikipedia:69 Transient global amnesia (TGA) is a neurological disorder whose key defining characteristic is a... more...

Related Diseases for Transient Global Amnesia

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Diseases related to Transient Global Amnesia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1transposition of the great arteries11.5
2transposition of the great arteries, dextro-looped 111.3
3conotruncal heart malformations10.9
4congenitally uncorrected transposition of the great arteries with cardiac malformation10.9
5congenitally uncorrected transposition of the great arteries with coarctation10.9
6congenitally corrected transposition of the great arteries10.7
7cerebritis10.6
8embryoma10.4ALDH7A1, PDE5A
9ischemia10.3
10congenital epulis10.3BDNF, KANTR
11color agnosia10.3EP300, KANTR
12cerebral degeneration10.3CRLF1, KANTR
13benign familial infantile epilepsy10.3BDNF, KANTR
14sick sinus syndrome10.2EP300, PDE5A
15purulent labyrinthitis10.2CRLF1, KANTR
16epilepsy10.2
17munchausen by proxy10.2ALDH7A1, PDE5A
18olfactory neuroblastoma10.2CRLF1, KANTR
19congenital hypoplastic anemia10.2KANTR, PSEN1
20diffuse alopecia areata10.2KANTR, PSEN1
21subclavian artery aneurysm10.2CRLF1, KANTR
22transposition of the great arteries, dextro-looped 210.2
23transposition of great arteries, dextro-looped 310.2
24vaginal tubular adenoma10.2BDNF, EP300, PSEN1
25peritoneal benign neoplasm10.2CRLF1, KANTR
26hepatitis c10.1ALDH7A1, PDE5A
27bile duct cystadenoma10.1KANTR, PSEN1
28retrograde amnesia10.1
29neuronitis10.1
30encephalitis10.1
31elephantiasis10.0EP300, PSEN1
32myocardial infarction10.0
33acute myocardial infarction10.0
34hydrocephalus10.0
35thrombocytopenia10.0
36aphasia10.0
37herpes simplex10.0
38hyperhomocysteinemia10.0
39heparin-induced thrombocytopenia10.0
40head injury10.0
41kidney osteogenic sarcoma10.0CA1, FOS
42med13l syndrome10.0
43acrofrontofacionasal dysostosis10.0KANTR, PSEN1
44angiomyolipoma10.0BDNF, KANTR, PSEN1
45chronic intestinal vascular insufficiency10.0BDNF, KANTR, PSEN1
46nasal cavity inverting papilloma10.0EP300, PSEN1
47thalassemia9.9
48ventricular septal defect9.9
49situs inversus9.9
50hemophilia9.9

Comorbidity relations with Transient Global Amnesia via Phenotypic Disease Network (PDN):


Hypertension, EssentialTransient Cerebral Ischemia

Graphical network of the top 20 diseases related to Transient Global Amnesia:



Diseases related to transient global amnesia

Symptoms for Transient Global Amnesia

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UMLS symptoms related to Transient Global Amnesia:


amaurosis fugax

Drugs & Therapeutics for Transient Global Amnesia

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Drugs for Transient Global Amnesia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MidazolamPhase 4, Phase 166159467-70-84192
Synonyms:
4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate
59467-70-8
8-Chlor-6-(2-fluorphenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepin
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride
8-Chloro-6-(O-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]-benzodiazepine
8-Chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine
AC-18749
AC1L1HMA
BIDD:GT0647
BRN 0625572
Buccolam
C07524
C18H13ClFN3
CHEMBL655
CID4192
D00550
DB00683
DEA No. 2884
Dazolam
Dea No. 2884
 
Dormicum
Dormicum (TN)
EINECS 261-774-5
LS-77780
Midanium
Midazolam
Midazolam (JAN/INN)
Midazolam Base
Midazolam Hcl
Midazolam [INN:BAN:JAN]
Midazolamum
Midazolamum [INN-Latin]
Midosed
MolPort-003-849-219
NCGC00168254-01
Ro 21-3981
TL8003787
UC429_SIGMA
UNII-R60L0SM5BC
Versed
ZINC00001732
midazolam
nchembio747-comp32
2
PropofolPhase 4, Phase 19852078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
3
ThiopentalPhase 13376-75-53000715
Synonyms:
()Thiopental solution
(+-)-Thiopental
(+/-)-THIOPENTAL
(+/-)Thiopental solution
2-Thio-5-ethyl-5-sec-pentylbarbituric acid
4,6,(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (9CI)
5-24-09-00172 (Beilstein Handbook Reference)
5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dione
5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid
5-ethyl-2-mercapto-5-(1-methylbutyl)pyrimidine-4,6(1H,5H)-dione
5-ethyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione
59709-53-4
76-75-5
AC-16029
AC1MHDBY
AC1Q2UJN
BRD-A72603112-236-02-4
BRN 0209361
BSPBio_003301
Bitaryl
C07521
C11H18N2O2S
CHEBI:102166
CHEMBL441
CID3000715
DB00599
DivK1c_000993
EINECS 200-984-3
I14-14129
IDI1_000993
Intraval
KBio1_000993
KBio2_002272
KBio2_004840
 
KBio2_007408
KBio3_002803
KBioGR_001010
KBioSS_002273
LS-24395
NCGC00159524-01
NINDS_000993
Omexolon
Penthiobarbital
Pentothal
Pentothiobarbital
SPBio_002215
Sodium Pentothal
Spectrum2_001998
Spectrum3_001781
Spectrum4_000575
Spectrum5_001692
Spectrum_001786
T1019_SIGMA
T1022_FLUKA
T1022_SIGMA
Thiomebumal
Thiomebumalum
Thionembutal
Thiopental
Thiopental [BAN]
Thiopentobarbital
Thiopentobarbitone
Thiopentobarbituric acid
Thiopentone
Thiothal
Tiopentale
Tiopentale [Italian]
Trapanal
UNII-JI8Z5M7NA3
thiopental
4
DexmedetomidinePhase 151576631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy of Propofol or Midazolam Compare to Placebo for Preoperative MedicationCompletedNCT01976845Phase 4
2Effect of Affective Content on Drug Induced Amnesia of Episodic MemoryCompletedNCT00142493Phase 1
3Pilot Study of Spinal Manipulation for Chronic Neck PainTerminatedNCT00030004Phase 1
4Perioperative Changes of Cognitive Function According to Jugular Vein Insufficiency in Robot-assisted ProstatectomyCompletedNCT01905488
5Propofol's Hypnotic and Memory EffectsCompletedNCT00576615
6Transient Global Amnesia (TGA). Exploratory Study of the Default Mode Network During the Acute PhaseRecruitingNCT02010853
7Longitudinal Monitoring of Cerebral Connectivity 3T MRI in Patients With a Transcient Global AmnesiaRecruitingNCT02796287
8Neuropsycholgy and Neuroimaging in Transient Global AmnesiaTerminatedNCT02562560

Search NIH Clinical Center for Transient Global Amnesia


Cochrane evidence based reviews: amnesia, transient global

Genetic Tests for Transient Global Amnesia

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Anatomical Context for Transient Global Amnesia

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MalaCards organs/tissues related to Transient Global Amnesia:

34
Temporal lobe, Brain, Heart, Cortex, Testes, Caudate nucleus, Pituitary

Animal Models for Transient Global Amnesia or affiliated genes

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Publications for Transient Global Amnesia

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Articles related to Transient Global Amnesia:

(show top 50)    (show all 544)
idTitleAuthorsYear
1
Hyperhomocysteinemia Association With Transient Global Amnesia: A Rare Case Report. (26417562)
2015
2
Teaching NeuroImages: Hippocampal foci of restricted diffusion in transient global amnesia. (26574541)
2015
3
Transient global amnesia like syndrome associated with acute infarction of the corpus callosum: a case report. (26643084)
2015
4
Longitudinal Cerebral Perfusion Change in Transient Global Amnesia Related to Left Posterior Medial Network Disruption. (26690067)
2015
5
Transient global amnesia associated with a unilateral infarction of the fornix: case report and review of the literature. (25628601)
2014
6
Reversible functional connectivity disturbances during transient global amnesia. (24623317)
2014
7
Stress-related factors in the emergence of transient global amnesia with hippocampal lesions. (25221484)
2014
8
Transient global amnesia and neurological events: the framingham heart study. (23675365)
2013
9
Transient global amnesia: a case report. (22949910)
2012
10
Letter by Griebe et al regarding article, "Jugular veins in transient global amnesia: innocent bystanders". (22989502)
2012
11
Jugular veins in transient global amnesia: innocent bystanders. (22811457)
2012
12
Transient global amnesia in a collegiate baseball player with type I diabetes mellitus: a case report. (21669103)
2011
13
Transient global amnesia as the presenting feature of heparin-induced thrombocytopenia. (20202039)
2010
14
Transient global amnesia - not so rare after all. (19452291)
2009
15
Recurrent transient global amnesia at high altitude. (18800962)
2008
16
Transient global amnesia after dobutamine--atropine stress echocardiography. (17698416)
2008
17
Transient global amnesia and brain lesions: new hints into clinical criteria. (18637952)
2008
18
Diffusion-weighted imaging in transient global amnesia exposes the CA1 region of the hippocampus. (17522744)
2007
19
The relationship between working memory and episodic memory disorders in transient global amnesia. (16697428)
2006
20
Transient global amnesia may be caused by cerebral vein thrombosis. (16061328)
2005
21
Transient global amnesia triggered by the intracarotid amobarbital procedure. (15710318)
2005
22
Hippocampal magnetic resonance imaging abnormalities in transient global amnesia. (16157757)
2005
23
Diffusion MRI in pure transient global amnesia associated with bilateral vertebral artery dissection. (14981348)
2004
24
Motor cortex excitability in transient global amnesia. (14999488)
2004
25
Transient global amnesia -- not always a benign process. (15242413)
2004
26
What causes transient global amnesia? New insights from DWI. (15210872)
2004
27
Time course of focal slow wave activity in transient ischemic attacks and transient global amnesia as measured by magnetoencephalography. (11059893)
2000
28
A SPECT study of the anatomy of transient global amnesia. (10847653)
2000
29
Clinical features, vascular risk factors, and prognosis for transient global amnesia in Chinese patients. (17895178)
1999
30
Transient global amnesia triggered by mild head injury. (9653523)
1998
31
Resting and acetazolamide-challenged technetium-99m-ECD SPECT in transient global amnesia. (9708507)
1998
32
Transient global amnesia and thalamic hemorrhage. (8930421)
1996
33
Acute confusional migraine: variant of transient global amnesia. (7779209)
1995
34
Sexual intercourse as a precipitating factor of transient global amnesia. (8411784)
1993
35
Neuropsychological and SPECT scan findings during and after transient global amnesia: evidence for the differential impairment of remote episodic memory. (8229038)
1993
36
Technetium-99m HM-PAO single photon emission computed tomography imaging in transient global amnesia. (1580818)
1992
37
Transient global amnesia and left frontal haemorrhage. (3174526)
1988
38
Transient global amnesia: a personal series of 60 cases. (3170164)
1988
39
Transient global amnesia: an analysis of 19 cases. (3623877)
1987
40
Transient global amnesia. When memory temporarily disappears. (3601846)
1987
41
Extracranial carotid artery in patients with transient global amnesia: evaluation by real-time B-mode ultrasonography with duplex Doppler flow. (2957822)
1987
42
Transient global amnesia: complication of arterial DSA. (3082139)
1986
43
Transient global amnesia after whiplash trauma. (4045494)
1985
44
Computer tomography in transient global amnesia. (7094948)
1982
45
Musical performance during transient global amnesia. (7188638)
1980
46
Transient global amnesia: manifestation of medial temporal lobe epilepsy. (455733)
1979
47
Transient global amnesia: clinical and electroencephalographic findings in 10 cases. (572010)
1979
48
Transient global amnesia. (448817)
1979
49
Transient global amnesia. Report of a case secondary to bilateral middle cerebral artery involvement. (722148)
1978
50
Transient global amnesia. (5347005)
1969

Variations for Transient Global Amnesia

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Expression for genes affiliated with Transient Global Amnesia

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Search GEO for disease gene expression data for Transient Global Amnesia.

Pathways for genes affiliated with Transient Global Amnesia

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GO Terms for genes affiliated with Transient Global Amnesia

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Biological processes related to Transient Global Amnesia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron apoptotic processGO:00435249.4BDNF, CRLF1, PSEN1

Sources for Transient Global Amnesia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet