TGA
MCID: TRN012
MIFTS: 43

Transient Global Amnesia (TGA) malady

Rare diseases, Neuronal diseases, Mental diseases categories
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Summaries for Transient Global Amnesia

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Sources:
8Disease Ontology, 43NIH Rare Diseases, 65Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Transient global amnesia (tga) is a condition characterized by sudden onset of memory loss and confusion. affected individuals are often disoriented in regard to time and place but usually remember their identity and can recognize family members. tga typically lasts for hours, although its duration may range from minutes to days. individuals usually have only one episode of tga during their life, although the condition reoccurs in about 5-25 percent of people. affected individuals do not experience symptoms after the episode of amnesia has resolved. last updated: 6/2/2009

MalaCards: Transient Global Amnesia, also known as amnesia, transient global, is related to migraine and ischemia. An important gene associated with Transient Global Amnesia is KLF6 (Kruppel-like factor 6). The compounds pge1 and folate have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe, brain and cortex.

Disease Ontology:8 An amnestic disorder that is characterized by temporary but almost total disruption of short-term memory with a range of problems accessing older memories.

Wikipedia:65 Transient global amnesia (TGA) is a neurological disorder whose key defining characteristic is a... more...

Aliases & Classifications for Transient Global Amnesia

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Sources:
8Disease Ontology, 43NIH Rare Diseases, 62UMLS, 27ICD9CM, 58SNOMED-CT, 35MeSH, 40NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases, Mental diseases


Aliases & Descriptions:

transient global amnesia 8 43
amnesia, transient global 62
tga 43


External Ids:

Disease Ontology8 DOID:13027
ICD9CM27 437.7
MeSH35 D020236
NCIt40 C85198
ICD1025 G45.4

Related Diseases for Transient Global Amnesia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Transient Global Amnesia:



Diseases related to transient global amnesia

Symptoms for Transient Global Amnesia

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Drugs & Therapeutics for Transient Global Amnesia

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Transient Global Amnesia

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Anatomical Context for Transient Global Amnesia

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33MalaCards
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MalaCards organs/tissues related to Transient Global Amnesia:

33
Temporal lobe, Brain, Cortex, Heart, Testes, Prefrontal cortex, Thalamus, Caudate nucleus, Pituitary

Animal Models for Transient Global Amnesia or affiliated genes

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Publications for Transient Global Amnesia

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52PubMed
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Articles related to Transient Global Amnesia:

(show top 50)    (show all 470)
idTitleAuthorsYear
1
Transient global amnesia and neurological events: the framingham heart study. (23675365)
2013
2
Clinical Experience of Modified Diffusion-Weighted Imaging Protocol for Lesion Detection in Transient Global Amnesia: An 8-Year Large-Scale Clinical Study. (23551898)
2013
3
Transient global amnesia and hippocampal foci of restricted diffusion. (23761513)
2013
4
Transient global amnesia, cerebral veins, and the need to find the 'smoking gun'. (22821610)
2012
5
Transient global amnesia: a case report. (22949910)
2012
6
Transient global amnesia as a revealing sign of giant transtentorial meningioma: case report and review of the literature. (21629022)
2011
7
Unmasking aortic dissection in patients of transient global amnesia: case report and diagnostic algorithm for the emergency department. (22715266)
2011
8
Transient global amnesia in a collegiate baseball player with type I diabetes mellitus: a case report. (21669103)
2011
9
What doctors should not forget about transient global amnesia. (20715896)
2010
10
Aortic dissection as a possible cause of pure transient global amnesia: a case report and literature review. (19294333)
2009
11
Transient global amnesia - not so rare after all. (19452291)
2009
12
Recurrent transient global amnesia at high altitude. (18800962)
2008
13
Transient global amnesia after dobutamine--atropine stress echocardiography. (17698416)
2008
14
Transient global amnesia associated with the infusion of DMSO-cryopreserved autologous peripheral blood stem cells. (18310533)
2008
15
Classical diseases revisited: transient global amnesia. (17403949)
2007
16
Diffusion-weighted imaging in transient global amnesia exposes the CA1 region of the hippocampus. (17522744)
2007
17
The relationship between working memory and episodic memory disorders in transient global amnesia. (16697428)
2006
18
Transient global amnesia: look at mechanisms not causes. (16966521)
2006
19
Evidence of acute ischemic tissue change in transient global amnesia in magnetic resonance imaging: case report and literature review. (15746236)
2005
20
Diffusion MRI in pure transient global amnesia associated with bilateral vertebral artery dissection. (14981348)
2004
21
Motor cortex excitability in transient global amnesia. (14999488)
2004
22
Time course of focal slow wave activity in transient ischemic attacks and transient global amnesia as measured by magnetoencephalography. (11059893)
2000
23
Transient global amnesia, migraine, thalamic infarct, dihydroergotamine, and sumatriptan. (10759939)
2000
24
Clinical features, vascular risk factors, and prognosis for transient global amnesia in Chinese patients. (17895178)
1999
25
Perfusion- and diffusion-weighted magnetic resonance imaging in transient global amnesia. (10408577)
1999
26
Transient global amnesia triggered by mild head injury. (9653523)
1998
27
Aetiology of transient global amnesia. (9717945)
1998
28
Resting and acetazolamide-challenged technetium-99m-ECD SPECT in transient global amnesia. (9708507)
1998
29
Transient global amnesia and migraine. A case control study. (9693225)
1998
30
Transient global amnesia and thalamic hemorrhage. (8930421)
1996
31
Acute confusional migraine: variant of transient global amnesia. (7779209)
1995
32
Sexual intercourse as a precipitating factor of transient global amnesia. (8411784)
1993
33
Neuropsychological and SPECT scan findings during and after transient global amnesia: evidence for the differential impairment of remote episodic memory. (8229038)
1993
34
Emotional arousal-induced transient global amnesia. A clue to the neural transcription of emotion? (1311457)
1992
35
Transient global amnesia associated with a right sphenoid ridge meningioma: a case report. (2177363)
1990
36
Transient global amnesia, epilepsy, and migraine: diagnostic comparisons and distinctions. (2505176)
1989
37
Transient global amnesia and left frontal haemorrhage. (3174526)
1988
38
Transient global amnesia precipitated by emotion in an adolescent. (3209845)
1988
39
Transient global amnesia: characterization of anterograde and retrograde amnesia. (3340282)
1988
40
Transient global amnesia: an analysis of 19 cases. (3623877)
1987
41
Transient global amnesia. (3683891)
1987
42
Transient global amnesia after coronary angiography. (3720046)
1986
43
Transient global amnesia. (6487093)
1984
44
Computer tomography in transient global amnesia. (7094948)
1982
45
Transient global amnesia due to glioma in the dominant hemisphere. (7188641)
1980
46
Transient global amnesia and temporary memory loss. (7393049)
1980
47
Transient global amnesia. (424819)
1979
48
Transient global amnesia: manifestation of medial temporal lobe epilepsy. (455733)
1979
49
Transient global amnesia. Report of a case secondary to bilateral middle cerebral artery involvement. (722148)
1978
50
The electroencephalogram in transient global amnesia. (4183235)
1969

Variations for Transient Global Amnesia

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Expression for genes affiliated with Transient Global Amnesia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Transient Global Amnesia

Search GEO for disease gene expression data for Transient Global Amnesia.

Pathways for genes affiliated with Transient Global Amnesia

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Compounds for genes affiliated with Transient Global Amnesia

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Sources:
45Novoseek, 61Tocris Bioscience, 29IUPHAR, 11DrugBank, 51PharmGKB, 24HMDB
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Compounds related to Transient Global Amnesia according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1pge1459.7APOH, PDE5A
2folate459.6APOH, PDE5A
3prostacyclin459.6APOH, PDE5A
4fibrinogen459.6APOH, KLF6
5lead459.5BDNF, PDE5A
6ibmx45 61 2911.5BDNF, PDE5A
7indomethacin45 29 61 1112.4PDE5A, BDNF
8chlorpromazine29 45 51 1112.4APOH, BDNF
9norepinephrine45 24 1111.4BDNF, PDE5A
10cocaine45 1110.4BDNF, APOH
11histamine45 29 2411.4BDNF, PDE5A
12acetylcholine45 51 29 24 1113.3BDNF, PDE5A
13valine459.3BDNF, APOH
14forskolin45 51 1111.3BDNF, PDE5A
15ethanol45 51 24 1112.3APOH, BDNF
16hydrogen45 2410.2PDE5A, BDNF
17iron45 2410.2APOH, BDNF
18nitric oxide45 24 1111.2APOH, PDE5A, KLF6
19sodium45 2410.1BDNF, PDE5A
20lysine459.1BDNF, APOH
21lactate459.0BDNF, APOH
22dopamine45 29 24 1112.0PDE5A, BDNF
23cyclic amp45 2410.0PDE5A, KLF6, BDNF
24gold458.9APOH, BDNF, PDE5A
25vegf458.9BDNF, APOH, PDE5A
26oxygen45 249.8PDE5A, BDNF, APOH
27zinc45 249.4APOH, PDE5A, KLF6, BDNF
28estrogen458.4PDE5A, APOH, KLF6, BDNF
29calcium45 51 24 1111.2BDNF, APOH, PDE5A

GO Terms for genes affiliated with Transient Global Amnesia

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Products for genes affiliated with Transient Global Amnesia

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  • Antibodies
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Sources for Transient Global Amnesia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet