TGA
MCID: TRN012
MIFTS: 43

Transient Global Amnesia (TGA) malady

Rare diseases, Neuronal diseases, Mental diseases categories

Summaries for Transient Global Amnesia

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Sources:
9Disease Ontology, 44NIH Rare Diseases, 66Wikipedia, 34MalaCards
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NIH Rare Diseases:44 Transient global amnesia (tga) is a condition characterized by sudden onset of memory loss and confusion. affected individuals are often disoriented in regard to time and place but usually remember their identity and can recognize family members. tga typically lasts for hours, although its duration may range from minutes to days. individuals usually have only one episode of tga during their life, although the condition reoccurs in about 5-25 percent of people. affected individuals do not experience symptoms after the episode of amnesia has resolved. last updated: 6/2/2009

MalaCards: Transient Global Amnesia, also known as amnesia, transient global, is related to migraine and ischemia. An important gene associated with Transient Global Amnesia is KLF6 (Kruppel-like factor 6). The compounds pge1 and folate have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe, brain and cortex.

Disease Ontology:9 An amnestic disorder that is characterized by temporary but almost total disruption of short-term memory with a range of problems accessing older memories.

Wikipedia:66 Transient global amnesia (TGA) is a neurological disorder whose key defining characteristic is a... more...

Aliases & Classifications for Transient Global Amnesia

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Sources:
9Disease Ontology, 44NIH Rare Diseases, 63UMLS, 28ICD9CM, 59SNOMED-CT, 36MeSH, 41NCIt, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases, Mental diseases


Aliases & Descriptions:

transient global amnesia 9 44
amnesia, transient global 63
tga 44


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Disease Ontology9 DOID:13027
ICD9CM28 437.7
MeSH36 D020236
NCIt41 C85198
ICD1026 G45.4

Related Diseases for Transient Global Amnesia

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Transient Global Amnesia:



Diseases related to transient global amnesia

Symptoms for Transient Global Amnesia

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Drugs & Therapeutics for Transient Global Amnesia

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Transient Global Amnesia

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Anatomical Context for Transient Global Amnesia

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Sources:
34MalaCards
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MalaCards organs/tissues related to Transient Global Amnesia:

34
Temporal lobe, Brain, Cortex, Heart, Testes, Prefrontal cortex, Thalamus, Caudate nucleus, Pituitary

Animal Models for Transient Global Amnesia or affiliated genes

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Publications for Transient Global Amnesia

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53PubMed
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Articles related to Transient Global Amnesia:

(show top 50)    (show all 470)
idTitleAuthorsYear
1
Transient global amnesia and neurological events: the framingham heart study. (23675365)
2013
2
Clinical Experience of Modified Diffusion-Weighted Imaging Protocol for Lesion Detection in Transient Global Amnesia: An 8-Year Large-Scale Clinical Study. (23551898)
2013
3
Transient global amnesia and hippocampal foci of restricted diffusion. (23761513)
2013
4
Transient global amnesia, cerebral veins, and the need to find the 'smoking gun'. (22821610)
2012
5
Transient global amnesia: a case report. (22949910)
2012
6
Transient global amnesia as a revealing sign of giant transtentorial meningioma: case report and review of the literature. (21629022)
2011
7
Unmasking aortic dissection in patients of transient global amnesia: case report and diagnostic algorithm for the emergency department. (22715266)
2011
8
Transient global amnesia in a collegiate baseball player with type I diabetes mellitus: a case report. (21669103)
2011
9
What doctors should not forget about transient global amnesia. (20715896)
2010
10
Aortic dissection as a possible cause of pure transient global amnesia: a case report and literature review. (19294333)
2009
11
Transient global amnesia - not so rare after all. (19452291)
2009
12
Recurrent transient global amnesia at high altitude. (18800962)
2008
13
Transient global amnesia after dobutamine--atropine stress echocardiography. (17698416)
2008
14
Transient global amnesia associated with the infusion of DMSO-cryopreserved autologous peripheral blood stem cells. (18310533)
2008
15
Classical diseases revisited: transient global amnesia. (17403949)
2007
16
Diffusion-weighted imaging in transient global amnesia exposes the CA1 region of the hippocampus. (17522744)
2007
17
The relationship between working memory and episodic memory disorders in transient global amnesia. (16697428)
2006
18
Transient global amnesia: look at mechanisms not causes. (16966521)
2006
19
Evidence of acute ischemic tissue change in transient global amnesia in magnetic resonance imaging: case report and literature review. (15746236)
2005
20
Diffusion MRI in pure transient global amnesia associated with bilateral vertebral artery dissection. (14981348)
2004
21
Motor cortex excitability in transient global amnesia. (14999488)
2004
22
Time course of focal slow wave activity in transient ischemic attacks and transient global amnesia as measured by magnetoencephalography. (11059893)
2000
23
Transient global amnesia, migraine, thalamic infarct, dihydroergotamine, and sumatriptan. (10759939)
2000
24
Clinical features, vascular risk factors, and prognosis for transient global amnesia in Chinese patients. (17895178)
1999
25
Perfusion- and diffusion-weighted magnetic resonance imaging in transient global amnesia. (10408577)
1999
26
Transient global amnesia triggered by mild head injury. (9653523)
1998
27
Aetiology of transient global amnesia. (9717945)
1998
28
Resting and acetazolamide-challenged technetium-99m-ECD SPECT in transient global amnesia. (9708507)
1998
29
Transient global amnesia and migraine. A case control study. (9693225)
1998
30
Transient global amnesia and thalamic hemorrhage. (8930421)
1996
31
Acute confusional migraine: variant of transient global amnesia. (7779209)
1995
32
Sexual intercourse as a precipitating factor of transient global amnesia. (8411784)
1993
33
Neuropsychological and SPECT scan findings during and after transient global amnesia: evidence for the differential impairment of remote episodic memory. (8229038)
1993
34
Emotional arousal-induced transient global amnesia. A clue to the neural transcription of emotion? (1311457)
1992
35
Transient global amnesia associated with a right sphenoid ridge meningioma: a case report. (2177363)
1990
36
Transient global amnesia, epilepsy, and migraine: diagnostic comparisons and distinctions. (2505176)
1989
37
Transient global amnesia and left frontal haemorrhage. (3174526)
1988
38
Transient global amnesia precipitated by emotion in an adolescent. (3209845)
1988
39
Transient global amnesia: characterization of anterograde and retrograde amnesia. (3340282)
1988
40
Transient global amnesia: an analysis of 19 cases. (3623877)
1987
41
Transient global amnesia. (3683891)
1987
42
Transient global amnesia after coronary angiography. (3720046)
1986
43
Transient global amnesia. (6487093)
1984
44
Computer tomography in transient global amnesia. (7094948)
1982
45
Transient global amnesia due to glioma in the dominant hemisphere. (7188641)
1980
46
Transient global amnesia and temporary memory loss. (7393049)
1980
47
Transient global amnesia. (424819)
1979
48
Transient global amnesia: manifestation of medial temporal lobe epilepsy. (455733)
1979
49
Transient global amnesia. Report of a case secondary to bilateral middle cerebral artery involvement. (722148)
1978
50
The electroencephalogram in transient global amnesia. (4183235)
1969

Variations for Transient Global Amnesia

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Expression for genes affiliated with Transient Global Amnesia

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Transient Global Amnesia

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Pathways for genes affiliated with Transient Global Amnesia

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Compounds for genes affiliated with Transient Global Amnesia

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Sources:
46Novoseek, 62Tocris Bioscience, 30IUPHAR, 12DrugBank, 52PharmGKB, 25HMDB
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Compounds related to Transient Global Amnesia according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1pge1469.7APOH, PDE5A
2folate469.6APOH, PDE5A
3prostacyclin469.6APOH, PDE5A
4fibrinogen469.6APOH, KLF6
5lead469.5BDNF, PDE5A
6ibmx46 62 3011.5BDNF, PDE5A
7indomethacin46 30 62 1212.4PDE5A, BDNF
8chlorpromazine30 46 52 1212.4APOH, BDNF
9norepinephrine46 25 1211.4BDNF, PDE5A
10cocaine46 1210.4BDNF, APOH
11histamine46 30 2511.4BDNF, PDE5A
12acetylcholine46 52 30 25 1213.3BDNF, PDE5A
13valine469.3BDNF, APOH
14forskolin46 52 1211.3BDNF, PDE5A
15ethanol46 52 25 1212.3APOH, BDNF
16hydrogen46 2510.2PDE5A, BDNF
17iron46 2510.2APOH, BDNF
18nitric oxide46 25 1211.2APOH, PDE5A, KLF6
19sodium46 2510.1BDNF, PDE5A
20lysine469.1BDNF, APOH
21lactate469.0BDNF, APOH
22dopamine46 30 25 1212.0PDE5A, BDNF
23cyclic amp46 2510.0PDE5A, KLF6, BDNF
24gold468.9APOH, BDNF, PDE5A
25vegf468.9BDNF, APOH, PDE5A
26oxygen46 259.8PDE5A, BDNF, APOH
27zinc46 259.4APOH, PDE5A, KLF6, BDNF
28estrogen468.4PDE5A, APOH, KLF6, BDNF
29calcium46 52 25 1211.2BDNF, APOH, PDE5A

GO Terms for genes affiliated with Transient Global Amnesia

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Products for genes affiliated with Transient Global Amnesia

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  • Antibodies
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Sources for Transient Global Amnesia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet