MCID: TRN002
MIFTS: 26

Transitional Meningioma malady

Summaries for Transitional Meningioma

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32MalaCards
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MalaCards: Transitional Meningioma, also known as transitional meningioma, is related to meningioma and glioblastoma multiforme. An important gene associated with Transitional Meningioma is NF2 (neurofibromin 2 (merlin)), and among its related pathways are Adhesion and Cell adhesion Cell-matrix glycoconjugates. The compounds dexamethasone and hematoxylin have been mentioned in the context of this disorder. Related mouse phenotype vision/eye.

Aliases & Classifications for Transitional Meningioma

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8Disease Ontology, 44Novoseek, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

transitional meningioma 8 44 60
transitional meningioma 8


External Ids:

Disease Ontology8 DOID:7213
MeSH34 D008579
SNOMED-CT56 64967004
NCIt39 C4333

Related Diseases for Transitional Meningioma

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17GeneCards, 18GeneDecks
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Diseases related to Transitional Meningioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 47)
idRelated DiseaseScoreTop Affiliating Genes
1meningioma30.6NCAM1, NF2, MUC1
2glioblastoma multiforme30.2HIF1A, NCAM1
3gastrointestinal stromal tumor10.0NF2
4perineurioma10.0MUC1
5benign meningioma10.0NF2
6hemangiopericytoma10.0MUC1
7secretory meningioma10.0MUC1
8hepatocellular carcinoma10.0HIF1A
9cystadenocarcinoma10.0MUC1
10von hippel-lindau disease10.0HIF1A
11wilms tumor10.0NCAM1
12rhabdoid tumor10.0MUC1
13medulloblastoma10.0NCAM1
14angiosarcoma10.0MUC1
15acute leukemia10.0NCAM1
16cystic fibrosis10.0NF2
17interstitial lung disease10.0MUC1
18fibrous meningioma10.0MUC1, NF2
19anaplastic ependymoma10.0MUC1, NF2
20melanoma10.0NF2, HIF1A
21malignant mesothelioma10.0NF2, MUC1
22malignant peripheral nerve sheath tumor10.0MUC1, NF2
23hemangioblastoma10.0MUC1, HIF1A
24sarcoma10.0MUC1, NF2
25neurilemmoma10.0MUC1, NF2
26benign mesothelioma10.0MUC1, NF2
27neurofibroma10.0MUC1, NF2
28chordoma10.0MUC1, NCAM1
29merkel cell carcinoma10.0MUC1, NCAM1
30tubular adenocarcinoma10.0NCAM1, MUC1
31adenoid cystic carcinoma10.0MUC1, NCAM1
32neuroendocrine carcinoma10.0MUC1, NCAM1
33renal clear cell carcinoma10.0HIF1A, MUC1
34carcinoid syndrome10.0MUC1, NCAM1
35paraganglioma10.0NCAM1, HIF1A
36cholangiocarcinoma10.0MUC1, NCAM1
37ependymoma10.0MUC1, NF2, NCAM1
38ischemia10.0HIF1A, NF2, NCAM1
39ovarian cancer10.0MUC1, HIF1A, NF2
40breast cancer10.0NF2, HIF1A, MUC1
41osteosarcoma10.0HIF1A, NF2
42colorectal cancer10.0MUC1, HIF1A, NF2
43malignant glioma10.0HIF1A, NF2, NCAM1
44pancreatic cancer10.0HIF1A, MUC1, GLRX
45astrocytoma10.0NCAM1, NF2, HIF1A
46adenocarcinoma10.0MUC1, HIF1A, NF2, NCAM1
47squamous cell carcinoma10.0HIF1A, MUC1, GLRX

Graphical network of the top 20 diseases related to Transitional Meningioma:



Diseases related to transitional meningioma

Clinical Features for Transitional Meningioma

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Drugs & Therapeutics for Transitional Meningioma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Transitional Meningioma

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Anatomical Context for Transitional Meningioma

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Animal Models for Transitional Meningioma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Transitional Meningioma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053917.5GLRX, MUC1, HIF1A, NF2, NCAM1

Publications for Transitional Meningioma

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50PubMed
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Articles related to Transitional Meningioma:

idTitleAuthorsYear
1
Histone deacetylase inhibitor AR-42 differentially affects cell-cycle transit in meningeal and meningioma cells, potently inhibiting NF2-deficient meningioma growth. (23151902)
2013
2
F-18 fluorodeoxyglucose positron emission tomography in a transitional meningioma. (19542958)
2009
3
Fronto-orbital intradiploic transitional meningioma. (18688153)
2008
4
Expression of hypoxia inducible factor-1alpha in tumors of patients with glioblastoma multiforme and transitional meningioma. (18621534)
2008
5
Relationship between DNA damage and total antioxidant capacity in patients with transitional meningioma. (17555871)
2007
6
Glutathione peroxidase, glutathione reductase and protein oxidation in patients with glioblastoma multiforme and transitional meningioma. (17457608)
2007
7
Cranioplasty of an extremely large cranial defect caused by transitional meningioma with a knitted polypropylen-polyester prothesis "Codubix". (1776518)
1991
8
Pathologic quiz case 1. Transitional (psammomatous) meningioma of the ethmoidal sinus. (2363928)
1990

Genetic Variations for Transitional Meningioma

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Expression for genes affiliated with Transitional Meningioma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Transitional Meningioma

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Pathways for genes affiliated with Transitional Meningioma

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4Cell Signaling Technology, 12EMD Millipore
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Pathways related to Transitional Meningioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3MUC1, NCAM1
2
Cell adhesion Cell-matrix glycoconjugates
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9.3MUC1, NCAM1

Compounds for genes affiliated with Transitional Meningioma

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44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB, 59Tocris Bioscience
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Compounds related to Transitional Meningioma according to GeneCards/GeneDecks:

(show all 24)
idCompoundScoreTop Affiliating Genes
1dexamethasone44 49 28 1112.6HIF1A
2hematoxylin449.5NCAM1, MUC1
3crcs449.4HIF1A, MUC1
4gsno449.4GLRX, HIF1A
5galactose449.4NCAM1, MUC1
6trastuzumab44 49 1111.4MUC1, HIF1A
7purine44 2410.3MUC1, NCAM1
8gemcitabine44 49 1111.2HIF1A, MUC1
9progesterone44 59 28 11 2413.1MUC1, NF2, NCAM1
10agar449.0MUC1, HIF1A, NF2
11adriamycin448.9GLRX, MUC1, HIF1A
12cisplatin44 49 59 1111.8GLRX, MUC1, HIF1A
13matrigel448.8MUC1, HIF1A, NCAM1
14dopamine44 28 11 2411.8NCAM1, HIF1A, GLRX
15vincristine44 49 1110.7NCAM1, HIF1A
16testosterone44 59 11 2411.7MUC1, HIF1A, NCAM1
17vegf448.5MUC1, HIF1A, NCAM1
18paraffin448.4NCAM1, NF2, HIF1A, MUC1
19threonine448.4NCAM1, NF2, HIF1A, MUC1
20nitric oxide44 11 2410.3NCAM1, HIF1A, MUC1, GLRX
21estrogen448.3NCAM1, HIF1A, MUC1, GLRX
22cysteine447.9GLRX, MUC1, HIF1A, NF2, NCAM1
23serine447.9GLRX, MUC1, HIF1A, NF2, NCAM1
24tyrosine447.9NCAM1, NF2, HIF1A, MUC1, GLRX

GO Terms for genes affiliated with Transitional Meningioma

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Products for genes affiliated with Transitional Meningioma

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  • Antibodies
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Sources for Transitional Meningioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet